Mus musculus

212 known processes

Rap1a

RAS-related protein-1a

(Aliases: AI848598,G-22K,Rap1,Krev-1,MGC102329)

Rap1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
guanosine containing compound metabolic process GO:1901068 144 0.423
organelle localization GO:0051640 179 0.381
guanosine containing compound catabolic process GO:1901069 144 0.360
nucleoside phosphate metabolic process GO:0006753 338 0.321
purine ribonucleoside metabolic process GO:0046128 241 0.281
gtp metabolic process GO:0046039 144 0.245
nucleoside metabolic process GO:0009116 246 0.227
organophosphate catabolic process GO:0046434 232 0.208
organic cyclic compound catabolic process GO:1901361 295 0.201
purine ribonucleoside catabolic process GO:0046130 205 0.198
nucleoside triphosphate metabolic process GO:0009141 230 0.194
ribonucleotide catabolic process GO:0009261 208 0.192
nucleotide catabolic process GO:0009166 217 0.171
nucleoside triphosphate catabolic process GO:0009143 205 0.168
regulation of kinase activity GO:0043549 249 0.147
Mouse Rat
membrane fusion GO:0061025 38 0.146
nucleobase containing small molecule metabolic process GO:0055086 352 0.142
small gtpase mediated signal transduction GO:0007264 97 0.141
gtp catabolic process GO:0006184 143 0.135
ribose phosphate metabolic process GO:0019693 291 0.133
purine nucleotide catabolic process GO:0006195 211 0.129
aromatic compound catabolic process GO:0019439 286 0.127
glycosyl compound metabolic process GO:1901657 246 0.126
glycosyl compound catabolic process GO:1901658 206 0.121
cellular nitrogen compound catabolic process GO:0044270 280 0.113
purine nucleoside triphosphate catabolic process GO:0009146 203 0.110
regulation of vesicle mediated transport GO:0060627 139 0.107
establishment of vesicle localization GO:0051650 81 0.101
establishment of synaptic vesicle localization GO:0097480 57 0.099
synaptic transmission GO:0007268 329 0.099
exocytosis GO:0006887 121 0.095
negative regulation of synaptic vesicle transport GO:1902804 3 0.094
establishment of organelle localization GO:0051656 122 0.094
purine containing compound catabolic process GO:0072523 213 0.091
regulation of protein kinase activity GO:0045859 232 0.085
Mouse Rat
regulation of protein localization GO:0032880 231 0.084
regulation of cellular component size GO:0032535 121 0.081
positive regulation of protein phosphorylation GO:0001934 242 0.080
Mouse Rat
nucleoside phosphate catabolic process GO:1901292 222 0.079
purine ribonucleotide catabolic process GO:0009154 208 0.076
organonitrogen compound catabolic process GO:1901565 264 0.075
organelle fission GO:0048285 170 0.075
purine containing compound metabolic process GO:0072521 311 0.071
wnt signaling pathway GO:0016055 188 0.070
heterocycle catabolic process GO:0046700 280 0.068
microtubule based process GO:0007017 236 0.067
nucleoside catabolic process GO:0009164 206 0.067
regulation of establishment of protein localization GO:0070201 181 0.066
synaptic vesicle localization GO:0097479 59 0.066
regulation of cellular catabolic process GO:0031329 242 0.066
Rat
immune effector process GO:0002252 321 0.064
purine nucleoside metabolic process GO:0042278 241 0.063
ribonucleoside metabolic process GO:0009119 245 0.063
purine ribonucleotide metabolic process GO:0009150 290 0.062
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.062
vesicle organization GO:0016050 60 0.058
negative regulation of protein metabolic process GO:0051248 282 0.058
regulation of cellular component biogenesis GO:0044087 181 0.058
Human
regulation of transferase activity GO:0051338 263 0.057
Mouse Rat
regulation of secretion by cell GO:1903530 249 0.057
regulation of organelle organization GO:0033043 289 0.057
ras protein signal transduction GO:0007265 77 0.057
Human Mouse Fly
positive regulation of protein modification process GO:0031401 299 0.057
Mouse Rat
cellular amine metabolic process GO:0044106 44 0.056
regulation of cellular amino acid metabolic process GO:0006521 5 0.055
actin cytoskeleton organization GO:0030036 220 0.055
regulation of secretion GO:0051046 274 0.055
protein autophosphorylation GO:0046777 61 0.055
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.054
positive regulation of cell death GO:0010942 224 0.054
cellular protein complex assembly GO:0043623 116 0.054
endocytosis GO:0006897 168 0.053
regulation of cellular amine metabolic process GO:0033238 20 0.052
mitotic cell cycle process GO:1903047 159 0.052
cellular lipid metabolic process GO:0044255 323 0.052
organelle fusion GO:0048284 28 0.052
membrane organization GO:0061024 245 0.051
regulation of mapk cascade GO:0043408 248 0.051
regulation of cell migration GO:0030334 219 0.048
Mouse
negative regulation of cellular component organization GO:0051129 194 0.048
meiotic cell cycle GO:0051321 122 0.047
regulation of intracellular transport GO:0032386 159 0.044
positive regulation of apoptotic process GO:0043065 217 0.043
protein localization to organelle GO:0033365 185 0.043
positive regulation of mapk cascade GO:0043410 170 0.042
cellular ketone metabolic process GO:0042180 84 0.042
cellular amino acid metabolic process GO:0006520 103 0.042
regulation of nucleotide catabolic process GO:0030811 122 0.041
Rat
nitrogen compound transport GO:0071705 271 0.040
negative regulation of molecular function GO:0044092 258 0.040
regulation of vasculature development GO:1901342 88 0.039
neurotransmitter transport GO:0006836 76 0.038
amine metabolic process GO:0009308 45 0.038
mitotic cell cycle GO:0000278 195 0.037
peptidyl tyrosine modification GO:0018212 145 0.036
Mouse
regulation of gtp catabolic process GO:0033124 113 0.036
Rat
ribonucleotide metabolic process GO:0009259 291 0.035
nuclear division GO:0000280 158 0.035
purine nucleoside catabolic process GO:0006152 205 0.035
negative regulation of exocytosis GO:0045920 12 0.035
vesicle fusion GO:0006906 16 0.035
carbohydrate derivative catabolic process GO:1901136 231 0.034
regulation of anatomical structure size GO:0090066 178 0.034
vesicle localization GO:0051648 86 0.034
regulation of hydrolase activity GO:0051336 246 0.034
Rat
negative regulation of neuron death GO:1901215 98 0.033
meiotic cell cycle process GO:1903046 77 0.033
circulatory system process GO:0003013 197 0.032
regulation of neuron differentiation GO:0045664 281 0.032
macromolecule catabolic process GO:0009057 281 0.032
actin filament organization GO:0007015 113 0.032
rho protein signal transduction GO:0007266 32 0.031
regulation of protein autophosphorylation GO:0031952 8 0.031
Mouse
cellular component assembly involved in morphogenesis GO:0010927 139 0.030
meiotic nuclear division GO:0007126 115 0.030
striated muscle tissue development GO:0014706 293 0.030
nucleotide metabolic process GO:0009117 332 0.030
regulation of cell division GO:0051302 76 0.030
neurotransmitter secretion GO:0007269 62 0.030
protein maturation GO:0051604 176 0.030
negative regulation of protein processing GO:0010955 79 0.029
organelle assembly GO:0070925 177 0.029
muscle tissue development GO:0060537 308 0.029
cellular chemical homeostasis GO:0055082 215 0.029
regulation of neurotransmitter levels GO:0001505 87 0.029
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
regulation of cell projection organization GO:0031344 206 0.028
negative regulation of secretion GO:0051048 61 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
regulation of jnk cascade GO:0046328 62 0.027
regulation of lymphocyte activation GO:0051249 240 0.027
cell cell junction organization GO:0045216 72 0.027
Fly
cell junction organization GO:0034330 77 0.027
Human Fly
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.027
Mouse
positive regulation of programmed cell death GO:0043068 218 0.027
cell adhesion GO:0007155 329 0.027
Fly
dna metabolic process GO:0006259 303 0.027
cytoplasmic transport GO:0016482 234 0.027
regulation of exocytosis GO:0017157 61 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.026
glycerolipid metabolic process GO:0046486 122 0.026
synaptic vesicle transport GO:0048489 57 0.025
protein localization to membrane GO:0072657 108 0.025
phospholipid metabolic process GO:0006644 87 0.025
carbohydrate metabolic process GO:0005975 230 0.025
regulation of cell cycle process GO:0010564 160 0.025
intracellular protein transport GO:0006886 204 0.024
activation of immune response GO:0002253 138 0.024
amide transport GO:0042886 138 0.024
regulation of membrane potential GO:0042391 192 0.024
spermatogenesis GO:0007283 284 0.024
protein localization to plasma membrane GO:0072659 57 0.024
regulation of protein transport GO:0051223 163 0.024
regulation of cytoskeleton organization GO:0051493 122 0.024
carbohydrate homeostasis GO:0033500 128 0.024
regulation of hormone levels GO:0010817 211 0.023
positive regulation of cellular component biogenesis GO:0044089 94 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
cell substrate adhesion GO:0031589 130 0.023
chromosome segregation GO:0007059 48 0.023
endomembrane system organization GO:0010256 147 0.023
regulation of synaptic vesicle transport GO:1902803 13 0.023
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.022
regulation of cytoplasmic transport GO:1903649 112 0.022
regulation of cell cycle GO:0051726 281 0.022
hematopoietic progenitor cell differentiation GO:0002244 143 0.022
negative regulation of cytoskeleton organization GO:0051494 36 0.022
stem cell development GO:0048864 219 0.022
Fly
regulation of synaptic vesicle exocytosis GO:2000300 11 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
establishment of protein localization to organelle GO:0072594 118 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
cell maturation GO:0048469 127 0.021
long term synaptic potentiation GO:0060291 25 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.021
Mouse
cell division GO:0051301 120 0.021
insulin secretion GO:0030073 89 0.021
male gamete generation GO:0048232 285 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
protein polymerization GO:0051258 57 0.021
blood vessel morphogenesis GO:0048514 285 0.020
regulation of cell activation GO:0050865 289 0.020
vacuole organization GO:0007033 38 0.020
myosin filament organization GO:0031033 3 0.020
nucleus localization GO:0051647 20 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
regulation of proteolysis GO:0030162 164 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
mapk cascade GO:0000165 281 0.020
regulation of protein maturation GO:1903317 96 0.020
oocyte construction GO:0007308 2 0.020
leukocyte mediated immunity GO:0002443 174 0.020
glycerophospholipid metabolic process GO:0006650 71 0.020
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.019
mitotic cytokinesis GO:0000281 4 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
negative regulation of cell motility GO:2000146 61 0.019
Mouse
hormone secretion GO:0046879 128 0.019
regulation of synapse structural plasticity GO:0051823 4 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
macromolecular complex disassembly GO:0032984 43 0.019
protein processing GO:0016485 163 0.019
regulation of protein complex assembly GO:0043254 83 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
Rat
cellular homeostasis GO:0019725 240 0.019
regionalization GO:0003002 337 0.018
Zebrafish
peptidyl tyrosine phosphorylation GO:0018108 143 0.018
Mouse
positive regulation of secretion GO:0051047 130 0.018
jnk cascade GO:0007254 72 0.018
establishment of protein localization to membrane GO:0090150 54 0.018
transmembrane transport GO:0055085 412 0.018
mitochondrion organization GO:0007005 134 0.018
neuron death GO:0070997 154 0.018
chemotaxis GO:0006935 247 0.017
stem cell differentiation GO:0048863 268 0.017
Fly
leukocyte differentiation GO:0002521 342 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
stress activated protein kinase signaling cascade GO:0031098 81 0.017
regulation of neurotransmitter transport GO:0051588 35 0.017
autophagy GO:0006914 45 0.017
positive regulation of cell adhesion GO:0045785 80 0.017
Fly
regulation of intracellular protein transport GO:0033157 82 0.017
positive regulation of gtp catabolic process GO:0033126 85 0.017
Rat
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.017
regulation of actin filament based process GO:0032970 99 0.017
regulation of response to wounding GO:1903034 189 0.017
regulation of protein catabolic process GO:0042176 108 0.016
multi organism behavior GO:0051705 62 0.016
muscle adaptation GO:0043500 39 0.016
cell cycle g1 s phase transition GO:0044843 57 0.016
response to light stimulus GO:0009416 135 0.016
regulation of neuron projection development GO:0010975 169 0.016
negative regulation of secretion by cell GO:1903531 54 0.016
protein targeting GO:0006605 143 0.016
cation transport GO:0006812 399 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
cell type specific apoptotic process GO:0097285 268 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.015
metal ion homeostasis GO:0055065 189 0.015
cytokinesis GO:0000910 17 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
Rat
plasma membrane organization GO:0007009 90 0.015
cytokine production GO:0001816 319 0.015
dna repair GO:0006281 107 0.015
negative regulation of protein maturation GO:1903318 79 0.015
regulation of cellular response to stress GO:0080135 159 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
regulation of actin polymerization or depolymerization GO:0008064 45 0.015
negative regulation of proteolysis GO:0045861 74 0.014
response to radiation GO:0009314 165 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
golgi vesicle transport GO:0048193 30 0.014
cellular ion homeostasis GO:0006873 165 0.014
dephosphorylation GO:0016311 129 0.014
spindle assembly involved in meiosis GO:0090306 4 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
positive regulation of intracellular transport GO:0032388 70 0.014
developmental maturation GO:0021700 193 0.014
histone modification GO:0016570 159 0.014
positive regulation of response to wounding GO:1903036 66 0.014
glucose homeostasis GO:0042593 128 0.014
actin filament depolymerization GO:0030042 15 0.014
cell junction assembly GO:0034329 52 0.014
Human Fly
memory GO:0007613 58 0.014
glycoprotein metabolic process GO:0009100 116 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
actin filament polymerization GO:0030041 44 0.013
establishment of protein localization to vacuole GO:0072666 4 0.013
positive regulation of transferase activity GO:0051347 167 0.013
Rat
apoptotic signaling pathway GO:0097190 306 0.013
axonogenesis GO:0007409 274 0.013
ossification GO:0001503 216 0.013
regulation of protein processing GO:0070613 96 0.013
regulation of vacuole organization GO:0044088 4 0.013
cation homeostasis GO:0055080 212 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
Rat
regulation of nucleotide metabolic process GO:0006140 169 0.013
Rat
lymphocyte differentiation GO:0030098 242 0.013
lymphocyte proliferation GO:0046651 164 0.013
positive regulation of neuron projection development GO:0010976 79 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
positive regulation of dna templated transcription elongation GO:0032786 2 0.012
adaptive immune response GO:0002250 155 0.012
peptide hormone secretion GO:0030072 109 0.012
receptor mediated endocytosis GO:0006898 51 0.012
blood circulation GO:0008015 195 0.012
regulation of protein depolymerization GO:1901879 26 0.012
regulation of actin cytoskeleton organization GO:0032956 84 0.012
meiotic chromosome segregation GO:0045132 19 0.012
negative regulation of protein depolymerization GO:1901880 21 0.012
wound healing GO:0042060 157 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
Rat
protein targeting to vacuole GO:0006623 3 0.012
retrograde transport endosome to golgi GO:0042147 2 0.012
epithelium migration GO:0090132 63 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
forebrain development GO:0030900 302 0.012
neural tube closure GO:0001843 90 0.012
cellular response to glucose stimulus GO:0071333 45 0.012
somitogenesis GO:0001756 69 0.012
Zebrafish
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.012
calcium ion dependent exocytosis GO:0017156 35 0.012
Mouse
positive regulation of hormone secretion GO:0046887 38 0.012
neuron apoptotic process GO:0051402 142 0.012
actin filament bundle assembly GO:0051017 40 0.012
regulation of adaptive immune response GO:0002819 90 0.011
regulation of cell shape GO:0008360 39 0.011
Fly
muscle system process GO:0003012 141 0.011
sequestering of metal ion GO:0051238 19 0.011
regulation of cell substrate adhesion GO:0010810 73 0.011
spermatid development GO:0007286 108 0.011
cellular protein catabolic process GO:0044257 155 0.011
adult behavior GO:0030534 135 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
skin development GO:0043588 220 0.011
Worm
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
receptor internalization GO:0031623 16 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
Rat
cellular metal ion homeostasis GO:0006875 151 0.011
protein localization to vacuole GO:0072665 4 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
single organism cell adhesion GO:0098602 156 0.011
Fly
cellular response to insulin stimulus GO:0032869 78 0.011
t cell activation GO:0042110 289 0.011
synaptic vesicle exocytosis GO:0016079 26 0.011
regulation of hormone secretion GO:0046883 88 0.011
mitochondrion distribution GO:0048311 4 0.011
divalent metal ion transport GO:0070838 172 0.011
leukocyte proliferation GO:0070661 172 0.011
neuromuscular process controlling balance GO:0050885 59 0.011
lipid homeostasis GO:0055088 63 0.011
heart process GO:0003015 94 0.011
regulation of transmembrane transport GO:0034762 128 0.011
positive regulation of cell cycle GO:0045787 92 0.011
striated muscle cell development GO:0055002 125 0.011
negative regulation of mapk cascade GO:0043409 65 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
positive regulation of nervous system development GO:0051962 221 0.011
positive regulation of cell development GO:0010720 237 0.011
positive regulation of protein autophosphorylation GO:0031954 4 0.010
Mouse
muscle cell development GO:0055001 133 0.010
calcium ion transport GO:0006816 159 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
germ cell development GO:0007281 185 0.010
peptide secretion GO:0002790 114 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
Rat
muscle cell differentiation GO:0042692 261 0.010
response to inorganic substance GO:0010035 96 0.010
synaptic vesicle recycling GO:0036465 19 0.010
divalent inorganic cation transport GO:0072511 178 0.010
regulation of lymphocyte mediated immunity GO:0002706 84 0.010
spindle assembly involved in female meiosis GO:0007056 3 0.010
metaphase plate congression GO:0051310 2 0.010
regulation of cell motility GO:2000145 236 0.010
Mouse
attachment of spindle microtubules to kinetochore GO:0008608 4 0.010
regulation of peptide hormone secretion GO:0090276 75 0.010
positive regulation of protein transport GO:0051222 93 0.010
negative regulation of cell migration GO:0030336 59 0.010
Mouse

Rap1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
eye and adnexa disease DOID:1492 0 0.025
eye disease DOID:5614 0 0.025
nervous system disease DOID:863 0 0.025
retinal degeneration DOID:8466 0 0.025
disease of anatomical entity DOID:7 0 0.025
retinal disease DOID:5679 0 0.025
sensory system disease DOID:0050155 0 0.025
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.010