|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.552
|
Fly |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.551
|
Fly |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.513
|
Fly |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.485
|
Fly |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.439
|
Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.397
|
Fly |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.327
|
Fly |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.316
|
Fly |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.307
|
Fly |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.242
|
Fly |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.238
|
Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.237
|
Fly |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.237
|
Fly |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.236
|
Fly |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.236
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.233
|
Fly |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.211
|
Fly |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.198
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.193
|
Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.193
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.191
|
Fly |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.188
|
Fly |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.188
|
Fly |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.187
|
Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.187
|
Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.186
|
Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.179
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.175
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.174
|
Fly |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.172
|
Fly |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.170
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.168
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.166
|
Fly |
|
|
epidermal growth factor receptor signaling pathway via i kappab kinase nf kappab cascade
|
GO:0038168 |
1 |
0.161
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.160
|
Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.158
|
Fly |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.157
|
Fly |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.152
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.152
|
Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.150
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.149
|
Fly |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.145
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.144
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.138
|
Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.129
|
Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.128
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.127
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.127
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.126
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.118
|
Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.117
|
Fly |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.115
|
Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.112
|
Fly |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.108
|
Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.108
|
Fly |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.107
|
Fly |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.106
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.106
|
Fly |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.098
|
Fly |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.098
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.098
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.097
|
Fly |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.096
|
Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.095
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.093
|
Fly |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.091
|
Fly |
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.091
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.088
|
Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.088
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.085
|
Fly |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.084
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.082
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.079
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.078
|
Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.078
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.075
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.075
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.073
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.073
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.072
|
|
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
4 |
0.070
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.069
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.068
|
Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.068
|
Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.067
|
Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.066
|
Fly |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.066
|
|
|
|
lipid phosphorylation
|
GO:0046834 |
25 |
0.064
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.064
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.063
|
Fly |
|
|
regulation of clathrin mediated endocytosis
|
GO:2000369 |
4 |
0.060
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.059
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.059
|
|
|
|
post embryonic retina morphogenesis in camera type eye
|
GO:0060060 |
3 |
0.059
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.059
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.059
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.058
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.058
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.057
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.057
|
Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.057
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.057
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.057
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.056
|
|
|
|
positive regulation of cardiac muscle contraction
|
GO:0060452 |
2 |
0.056
|
|
|
|
negative regulation of phospholipase activity
|
GO:0010519 |
4 |
0.056
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.056
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.055
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.055
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.055
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.054
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.053
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.052
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.052
|
Fly |
|
|
t cell activation
|
GO:0042110 |
289 |
0.052
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.051
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.051
|
|
|
|
negative regulation of nik nf kappab signaling
|
GO:1901223 |
2 |
0.051
|
|
|
|
negative regulation of t cell mediated cytotoxicity
|
GO:0001915 |
3 |
0.048
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.047
|
|
|
|
negative regulation of camp mediated signaling
|
GO:0043951 |
3 |
0.047
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.047
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.047
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.047
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.047
|
|
|
|
negative regulation of g protein coupled receptor protein signaling pathway
|
GO:0045744 |
12 |
0.046
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.046
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.045
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.043
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.043
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.043
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.043
|
Fly |
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.042
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.042
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.042
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.041
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.039
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.039
|
Fly |
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.039
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.039
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.039
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.038
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.038
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.038
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.038
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.038
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.038
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.037
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.037
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.037
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.037
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.037
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.036
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.035
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.035
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.034
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.034
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.034
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.034
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.034
|
|
|
|
relaxation of muscle
|
GO:0090075 |
18 |
0.033
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.033
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.033
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.033
|
|
|
|
phototransduction
|
GO:0007602 |
17 |
0.032
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.032
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.032
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.032
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.032
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.032
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.032
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.031
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.031
|
Human |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.031
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.031
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.031
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.030
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.030
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.030
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.030
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.029
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.029
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.028
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.028
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.028
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.028
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.028
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.028
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.028
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.028
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.028
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.027
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.027
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.027
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.027
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.026
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.026
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.026
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.026
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.026
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.026
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.026
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.026
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.026
|
|
|
|
photoreceptor cell morphogenesis
|
GO:0008594 |
3 |
0.025
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.025
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.025
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.025
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.024
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.024
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.024
|
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.024
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.024
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.024
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.024
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.024
|
Human |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.024
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.024
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.024
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.023
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.023
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.023
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.023
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
12 |
0.023
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.023
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.023
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.023
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.023
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.023
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.023
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.023
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.023
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.023
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.023
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.023
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.022
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.022
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.022
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.022
|
|
|
|
regulation of adrenergic receptor signaling pathway
|
GO:0071877 |
4 |
0.022
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.022
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.022
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.022
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.022
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.022
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.021
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.021
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.021
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.021
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.021
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.021
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.021
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.021
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.021
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.021
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.021
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.021
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.021
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.020
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.020
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.020
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.020
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.020
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.020
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.020
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.020
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.020
|
Fly |
|
|
intra golgi vesicle mediated transport
|
GO:0006891 |
1 |
0.020
|
|
|
|
epidermal growth factor receptor signaling pathway via positive regulation of nf kappab transcription factor activity
|
GO:0038167 |
1 |
0.020
|
|
|
|
gonad morphogenesis
|
GO:0035262 |
1 |
0.020
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.019
|
|
|
|
positive regulation of striated muscle contraction
|
GO:0045989 |
3 |
0.019
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.019
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.019
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.019
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.019
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.019
|
Fly |
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.019
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.019
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.019
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.019
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.019
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.018
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.018
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.018
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.018
|
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.018
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.018
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.018
|
Human |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.018
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.018
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.018
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.018
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.018
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
2 |
0.018
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.018
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.018
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.017
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.017
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.017
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.017
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.017
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.017
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.017
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.017
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.017
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.017
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.017
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.017
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.017
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.017
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.017
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.017
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.017
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.017
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.017
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.017
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.017
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.017
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.016
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.016
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.016
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.016
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.016
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.016
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.016
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.016
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.016
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.016
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.016
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.016
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.016
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.016
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.016
|
Human |
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.016
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.016
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.016
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.016
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.016
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
1 |
0.016
|
|
|
|
relaxation of smooth muscle
|
GO:0044557 |
8 |
0.016
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.016
|
|
|
|
regulation of lamellipodium assembly
|
GO:0010591 |
3 |
0.016
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.016
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.016
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.016
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.016
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.015
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.015
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.015
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.015
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.015
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.015
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.015
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.015
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.015
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.015
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.015
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.015
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.015
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
33 |
0.015
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.015
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.015
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.015
|
|
|
|
cellular response to ethanol
|
GO:0071361 |
3 |
0.015
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.015
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.015
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.015
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.015
|
Fly |
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.015
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.015
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.015
|
|
|
|
platelet derived growth factor receptor beta signaling pathway
|
GO:0035791 |
4 |
0.015
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.015
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
81 |
0.015
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.015
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.015
|
Fly |
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
1 |
0.015
|
|
|
|
norepinephrine secretion
|
GO:0048243 |
2 |
0.014
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.014
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.014
|
Human |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.014
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.014
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.014
|
|
|
|
dorsal ventral axon guidance
|
GO:0033563 |
3 |
0.014
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.014
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.014
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.014
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.014
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.014
|
|
|
|
negative regulation of lipase activity
|
GO:0060192 |
7 |
0.014
|
|
|
|
nuclear export
|
GO:0051168 |
34 |
0.014
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.014
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.014
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.014
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.014
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.014
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.014
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.014
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.014
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.014
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.014
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.014
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.014
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.014
|
Human |
|
|
relaxation of cardiac muscle
|
GO:0055119 |
9 |
0.014
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.014
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.014
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.014
|
|
|
|
detection of light stimulus
|
GO:0009583 |
25 |
0.014
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.014
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.014
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.014
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.013
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.013
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.013
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.013
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.013
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.013
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.013
|
|
|
|
negative regulation of protein autophosphorylation
|
GO:0031953 |
2 |
0.013
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.013
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
30 |
0.013
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.013
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.013
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.013
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.013
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.013
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.013
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.013
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.013
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.013
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.013
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.013
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.013
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.013
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.013
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.013
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.013
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.013
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.013
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.013
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.013
|
|
|
|
sensory system development
|
GO:0048880 |
3 |
0.013
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.012
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.012
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.012
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.012
|
Fly |
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.012
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
52 |
0.012
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.012
|
Fly |
|
|
positive regulation of oocyte development
|
GO:0060282 |
4 |
0.012
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.012
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.012
|
Fly |
|
|
cytokine production
|
GO:0001816 |
319 |
0.012
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.012
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.012
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
30 |
0.012
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.012
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.012
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
15 |
0.012
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.012
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.012
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.012
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.012
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.012
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.012
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.012
|
Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.012
|
Human |
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.012
|
Fly |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.012
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.012
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.012
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.012
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.012
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.012
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.012
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.012
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.012
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
47 |
0.012
|
|
|
|
cell proliferation involved in outflow tract morphogenesis
|
GO:0061325 |
4 |
0.012
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.012
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.012
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.012
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.012
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.012
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.012
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.012
|
|
|
|
camp mediated signaling
|
GO:0019933 |
15 |
0.012
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.012
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.012
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.012
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.012
|
|
