Mus musculus

0 known processes

Rassf1

Ras association (RalGDS/AF-6) domain family member 1

(Aliases: AU044980,NORE2A,Rassf1A,Rassf1C,Rassf1B,REH3P21,123F2,AA536941,RDA32)

Rassf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transferase activity GO:0051338 263 0.184
positive regulation of apoptotic process GO:0043065 217 0.175
dna metabolic process GO:0006259 303 0.170
endothelial cell apoptotic process GO:0072577 9 0.147
positive regulation of apoptotic signaling pathway GO:2001235 95 0.135
regulation of protein kinase activity GO:0045859 232 0.133
mitotic cell cycle process GO:1903047 159 0.129
cellular response to dna damage stimulus GO:0006974 207 0.127
Human
positive regulation of protein phosphorylation GO:0001934 242 0.113
mitotic cell cycle GO:0000278 195 0.108
cell type specific apoptotic process GO:0097285 268 0.107
protein modification by small protein conjugation GO:0032446 187 0.099
Human Mouse
macromolecule catabolic process GO:0009057 281 0.097
neuron death GO:0070997 154 0.095
modification dependent macromolecule catabolic process GO:0043632 133 0.094
regulation of neuron death GO:1901214 134 0.091
positive regulation of transferase activity GO:0051347 167 0.090
regulation of apoptotic signaling pathway GO:2001233 197 0.090
positive regulation of kinase activity GO:0033674 155 0.085
mitotic cytokinesis GO:0000281 4 0.078
modification dependent protein catabolic process GO:0019941 133 0.078
regulation of cellular catabolic process GO:0031329 242 0.077
negative regulation of molecular function GO:0044092 258 0.077
positive regulation of cell death GO:0010942 224 0.076
response to growth factor GO:0070848 198 0.073
regulation of defense response GO:0031347 233 0.071
cellular amino acid metabolic process GO:0006520 103 0.071
signal transduction by p53 class mediator GO:0072331 51 0.067
ubiquitin dependent protein catabolic process GO:0006511 129 0.064
negative regulation of phosphate metabolic process GO:0045936 184 0.063
regulation of protein maturation GO:1903317 96 0.061
proteasomal protein catabolic process GO:0010498 98 0.060
regulation of cellular response to stress GO:0080135 159 0.059
negative regulation of phosphorylation GO:0042326 166 0.059
negative regulation of phosphorus metabolic process GO:0010563 184 0.057
cellular amine metabolic process GO:0044106 44 0.057
mapk cascade GO:0000165 281 0.054
leukocyte differentiation GO:0002521 342 0.053
Mouse
skeletal muscle organ development GO:0060538 163 0.051
ion transmembrane transport GO:0034220 361 0.051
cellular response to growth factor stimulus GO:0071363 197 0.051
positive regulation of protein modification process GO:0031401 299 0.050
Human Mouse
positive regulation of programmed cell death GO:0043068 218 0.050
protein localization to organelle GO:0033365 185 0.048
Mouse
protein catabolic process GO:0030163 221 0.046
chromatin modification GO:0016568 187 0.046
negative regulation of intracellular signal transduction GO:1902532 167 0.045
Mouse
protein processing GO:0016485 163 0.044
negative regulation of transferase activity GO:0051348 85 0.044
apoptotic signaling pathway GO:0097190 306 0.043
transmembrane transport GO:0055085 412 0.042
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.042
protein ubiquitination GO:0016567 171 0.040
Human Mouse
t cell activation GO:0042110 289 0.040
negative regulation of protein phosphorylation GO:0001933 126 0.039
intrinsic apoptotic signaling pathway GO:0097193 132 0.039
cell division GO:0051301 120 0.038
amine metabolic process GO:0009308 45 0.038
negative regulation of cellular amine metabolic process GO:0033239 1 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
cellular protein catabolic process GO:0044257 155 0.036
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.036
cellular macromolecule catabolic process GO:0044265 206 0.036
negative regulation of kinase activity GO:0033673 81 0.036
striated muscle tissue development GO:0014706 293 0.036
regulation of kinase activity GO:0043549 249 0.036
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.034
muscle tissue development GO:0060537 308 0.034
protein maturation GO:0051604 176 0.034
negative regulation of response to wounding GO:1903035 77 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.032
inflammatory response GO:0006954 244 0.032
cation transport GO:0006812 399 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
response to transforming growth factor beta GO:0071559 88 0.031
organic cyclic compound catabolic process GO:1901361 295 0.031
negative regulation of lymphocyte activation GO:0051250 91 0.031
negative regulation of protein maturation GO:1903318 79 0.031
negative regulation of proteolysis GO:0045861 74 0.031
adult behavior GO:0030534 135 0.031
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.030
negative regulation of cell cycle arrest GO:0071157 1 0.030
Human
response to reactive oxygen species GO:0000302 56 0.030
purine nucleotide metabolic process GO:0006163 302 0.029
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.029
negative regulation of protein modification process GO:0031400 163 0.028
muscle system process GO:0003012 141 0.028
regionalization GO:0003002 337 0.028
anion transmembrane transport GO:0098656 71 0.028
lens morphogenesis in camera type eye GO:0002089 24 0.027
cell adhesion GO:0007155 329 0.027
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.027
stem cell differentiation GO:0048863 268 0.027
posttranscriptional regulation of gene expression GO:0010608 155 0.027
Human
regulation of mapk cascade GO:0043408 248 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
Mouse
neuron apoptotic process GO:0051402 142 0.026
negative regulation of cell activation GO:0050866 111 0.026
aromatic compound catabolic process GO:0019439 286 0.026
cell cycle g1 s phase transition GO:0044843 57 0.026
regulation of reactive oxygen species metabolic process GO:2000377 40 0.025
negative regulation of immune system process GO:0002683 209 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.025
cellular response to cytokine stimulus GO:0071345 189 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
regulation of protein ubiquitination GO:0031396 52 0.025
Human Mouse
regulation of response to dna damage stimulus GO:2001020 34 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
regulation of protein stability GO:0031647 52 0.025
Human
homeostasis of number of cells GO:0048872 210 0.024
Mouse
striated muscle cell development GO:0055002 125 0.024
b cell activation GO:0042113 161 0.024
regulation of inflammatory response GO:0050727 147 0.024
intracellular receptor signaling pathway GO:0030522 74 0.024
synaptic transmission GO:0007268 329 0.024
g1 s transition of mitotic cell cycle GO:0000082 57 0.023
cellular response to biotic stimulus GO:0071216 92 0.023
camera type eye development GO:0043010 266 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.022
Human Mouse
reactive oxygen species metabolic process GO:0072593 84 0.022
traversing start control point of mitotic cell cycle GO:0007089 2 0.022
embryonic organ morphogenesis GO:0048562 276 0.022
jnk cascade GO:0007254 72 0.022
fat cell differentiation GO:0045444 160 0.022
regulation of mitotic cell cycle GO:0007346 126 0.021
chromatin assembly GO:0031497 13 0.021
angiogenesis GO:0001525 201 0.021
regulation of cell migration GO:0030334 219 0.021
positive regulation of cellular catabolic process GO:0031331 148 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
cellular response to lipopolysaccharide GO:0071222 77 0.021
forebrain development GO:0030900 302 0.020
carboxylic acid transport GO:0046942 100 0.020
anion transport GO:0006820 177 0.020
regulation of protein catabolic process GO:0042176 108 0.020
gland development GO:0048732 330 0.020
myeloid leukocyte activation GO:0002274 83 0.020
regulation of protein processing GO:0070613 96 0.020
cytokine production GO:0001816 319 0.020
regulation of cell cycle g1 s phase transition GO:1902806 35 0.020
extracellular matrix organization GO:0030198 147 0.020
circulatory system process GO:0003013 197 0.020
methylation GO:0032259 134 0.019
dendrite development GO:0016358 115 0.019
protein localization to nucleus GO:0034504 121 0.019
Mouse
mitotic cell cycle checkpoint GO:0007093 31 0.019
regulation of cytokine production GO:0001817 266 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
peptidyl amino acid modification GO:0018193 336 0.019
response to drug GO:0042493 75 0.019
response to extracellular stimulus GO:0009991 127 0.019
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.019
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 3 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
skeletal system development GO:0001501 356 0.018
Mouse
negative regulation of protein catabolic process GO:0042177 36 0.018
response to light stimulus GO:0009416 135 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
response to lipopolysaccharide GO:0032496 128 0.018
positive regulation of chromatin modification GO:1903310 28 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
t cell differentiation in thymus GO:0033077 77 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.018
cell activation involved in immune response GO:0002263 126 0.018
response to oxidative stress GO:0006979 123 0.018
organic anion transport GO:0015711 137 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
fertilization GO:0009566 127 0.017
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.017
regulation of cell cycle GO:0051726 281 0.017
Human
regulation of fat cell differentiation GO:0045598 81 0.017
positive regulation of neuron death GO:1901216 28 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017
regulation of cell activation GO:0050865 289 0.017
sensory organ morphogenesis GO:0090596 242 0.017
retina development in camera type eye GO:0060041 119 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
Human
response to radiation GO:0009314 165 0.016
muscle contraction GO:0006936 101 0.016
response to acid chemical GO:0001101 111 0.016
purine containing compound metabolic process GO:0072521 311 0.016
cellular ketone metabolic process GO:0042180 84 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
nuclear division GO:0000280 158 0.016
peptidyl lysine modification GO:0018205 77 0.016
lymphocyte differentiation GO:0030098 242 0.016
leukocyte proliferation GO:0070661 172 0.016
negative regulation of cell cycle GO:0045786 123 0.016
Human
nucleotide metabolic process GO:0009117 332 0.016
response to nutrient levels GO:0031667 109 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
Mouse
cation transmembrane transport GO:0098655 266 0.016
skeletal muscle cell differentiation GO:0035914 66 0.015
negative regulation of cellular catabolic process GO:0031330 47 0.015
mrna metabolic process GO:0016071 84 0.015
negative regulation of mapk cascade GO:0043409 65 0.015
lymphocyte proliferation GO:0046651 164 0.015
peptidyl serine modification GO:0018209 83 0.015
regulation of stress activated mapk cascade GO:0032872 69 0.015
immune response regulating signaling pathway GO:0002764 125 0.015
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
negative regulation of chemotaxis GO:0050922 11 0.015
ras protein signal transduction GO:0007265 77 0.015
Human
respiratory tube development GO:0030323 167 0.015
positive regulation of cell activation GO:0050867 158 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.015
heart morphogenesis GO:0003007 178 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
regulation of response to wounding GO:1903034 189 0.015
regulation of lymphocyte mediated immunity GO:0002706 84 0.015
negative regulation of cellular protein catabolic process GO:1903363 22 0.015
regulation of hormone levels GO:0010817 211 0.015
heterocycle catabolic process GO:0046700 280 0.015
compound eye development GO:0048749 1 0.015
regulation of mitotic cell cycle phase transition GO:1901990 73 0.015
renal system development GO:0072001 225 0.014
skin development GO:0043588 220 0.014
cytokine mediated signaling pathway GO:0019221 115 0.014
nucleoside metabolic process GO:0009116 246 0.014
locomotory behavior GO:0007626 195 0.014
cellular homeostasis GO:0019725 240 0.014
extracellular structure organization GO:0043062 148 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
carbohydrate metabolic process GO:0005975 230 0.014
cellular chemical homeostasis GO:0055082 215 0.014
activation of immune response GO:0002253 138 0.014
anatomical structure homeostasis GO:0060249 145 0.014
blood vessel morphogenesis GO:0048514 285 0.014
single organismal cell cell adhesion GO:0016337 131 0.014
positive regulation of cell cycle g1 s phase transition GO:1902808 9 0.014
regulation of notch signaling pathway GO:0008593 35 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
digestive tract development GO:0048565 190 0.014
nucleotide catabolic process GO:0009166 217 0.014
interleukin 8 production GO:0032637 4 0.014
leukocyte migration GO:0050900 124 0.014
positive regulation of cellular protein catabolic process GO:1903364 34 0.014
organic acid transport GO:0015849 101 0.014
regulation of secretion by cell GO:1903530 249 0.014
response to inorganic substance GO:0010035 96 0.014
response to molecule of bacterial origin GO:0002237 143 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
blood circulation GO:0008015 195 0.013
histone modification GO:0016570 159 0.013
purine containing compound catabolic process GO:0072523 213 0.013
cellularization GO:0007349 1 0.013
germ cell development GO:0007281 185 0.013
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.013
positive regulation of immune effector process GO:0002699 107 0.013
positive regulation of defense response GO:0031349 124 0.013
positive regulation of cell motility GO:2000147 116 0.013
cellular response to inorganic substance GO:0071241 37 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
chromatin assembly or disassembly GO:0006333 16 0.013
leukocyte mediated immunity GO:0002443 174 0.013
regulation of cellular amino acid metabolic process GO:0006521 5 0.013
positive regulation of cell cycle GO:0045787 92 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
regulation of t cell activation GO:0050863 170 0.013
positive regulation of cell cycle phase transition GO:1901989 17 0.013
regulation of ion transport GO:0043269 215 0.013
adaptive immune response GO:0002250 155 0.013
positive regulation of innate immune response GO:0045089 80 0.013
endomembrane system organization GO:0010256 147 0.013
dna conformation change GO:0071103 37 0.013
regulation of hydrolase activity GO:0051336 246 0.013
regulation of circadian sleep wake cycle GO:0042749 3 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
nitrogen compound transport GO:0071705 271 0.013
regulation of innate immune response GO:0045088 91 0.012
regulation of translation GO:0006417 71 0.012
myeloid cell homeostasis GO:0002262 114 0.012
meiotic cell cycle GO:0051321 122 0.012
tube formation GO:0035148 140 0.012
developmental maturation GO:0021700 193 0.012
t cell differentiation GO:0030217 174 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
notch signaling pathway GO:0007219 71 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
lens development in camera type eye GO:0002088 62 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
regulation of cell adhesion GO:0030155 154 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
dephosphorylation GO:0016311 129 0.012
cellular response to external stimulus GO:0071496 88 0.012
immune effector process GO:0002252 321 0.012
regulation of map kinase activity GO:0043405 120 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
positive regulation of nervous system development GO:0051962 221 0.012
negative regulation of inflammatory response GO:0050728 61 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
cellular response to lipid GO:0071396 145 0.012
telencephalon development GO:0021537 186 0.012
regulation of proteasomal protein catabolic process GO:0061136 46 0.012
dna packaging GO:0006323 30 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
divalent inorganic cation transport GO:0072511 178 0.012
endocytosis GO:0006897 168 0.012
lung development GO:0030324 164 0.012
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.011
organelle assembly GO:0070925 177 0.011
regulation of membrane potential GO:0042391 192 0.011
regulation of blood pressure GO:0008217 93 0.011
negative regulation of cell growth GO:0030308 44 0.011
pallium development GO:0021543 120 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
sensory perception GO:0007600 245 0.011
protein oligomerization GO:0051259 67 0.011
ossification GO:0001503 216 0.011
Mouse
rna processing GO:0006396 105 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
gtp catabolic process GO:0006184 143 0.011
ear development GO:0043583 200 0.011
regulation of cell motility GO:2000145 236 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
glucose homeostasis GO:0042593 128 0.011
dna replication GO:0006260 52 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
neural tube development GO:0021915 160 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
cell fate commitment GO:0045165 210 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
regulation of organelle organization GO:0033043 289 0.011
muscle fiber development GO:0048747 76 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
glycosyl compound metabolic process GO:1901657 246 0.010
cell growth GO:0016049 130 0.010
exocytosis GO:0006887 121 0.010
organophosphate catabolic process GO:0046434 232 0.010
adult walking behavior GO:0007628 41 0.010
negative regulation of endothelial cell migration GO:0010596 4 0.010
response to organic cyclic compound GO:0014070 198 0.010
maintenance of location GO:0051235 89 0.010
cellular response to nitric oxide GO:0071732 4 0.010
regulation of interleukin 8 production GO:0032677 3 0.010
male gamete generation GO:0048232 285 0.010
gtp metabolic process GO:0046039 144 0.010
cytokine metabolic process GO:0042107 71 0.010
sperm individualization GO:0007291 1 0.010
response to endoplasmic reticulum stress GO:0034976 53 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
positive regulation of map kinase activity GO:0043406 84 0.010
rho protein signal transduction GO:0007266 32 0.010
chromosome segregation GO:0007059 48 0.010
muscle cell development GO:0055001 133 0.010
epithelial cell proliferation GO:0050673 174 0.010
spermatid differentiation GO:0048515 115 0.010
regulation of muscle tissue development GO:1901861 97 0.010

Rassf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.029
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
immune system disease DOID:2914 0 0.016
sensory system disease DOID:0050155 0 0.014
connective tissue disease DOID:65 0 0.010
musculoskeletal system disease DOID:17 0 0.010
bone disease DOID:0080001 0 0.010