Mus musculus

26 known processes

Rbbp8

retinoblastoma binding protein 8

(Aliases: 9930104E21Rik,CtIP)

Rbbp8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear division GO:0000280 158 0.211
microtubule cytoskeleton organization GO:0000226 157 0.206
organelle fission GO:0048285 170 0.199
cellular response to dna damage stimulus GO:0006974 207 0.197
Human
microtubule based process GO:0007017 236 0.170
meiotic cell cycle GO:0051321 122 0.105
cellular amino acid metabolic process GO:0006520 103 0.099
response to radiation GO:0009314 165 0.098
purine ribonucleotide metabolic process GO:0009150 290 0.097
mitotic cell cycle GO:0000278 195 0.090
cellular ketone metabolic process GO:0042180 84 0.082
dna metabolic process GO:0006259 303 0.079
Human
negative regulation of cellular component organization GO:0051129 194 0.078
regulation of cell cycle process GO:0010564 160 0.073
cellular nitrogen compound catabolic process GO:0044270 280 0.073
Human
glycosyl compound metabolic process GO:1901657 246 0.072
regulation of cellular amine metabolic process GO:0033238 20 0.071
meiotic cell cycle process GO:1903046 77 0.070
cellular macromolecule catabolic process GO:0044265 206 0.069
Human
glycosyl compound catabolic process GO:1901658 206 0.069
regulation of cell cycle GO:0051726 281 0.068
amine metabolic process GO:0009308 45 0.066
male gamete generation GO:0048232 285 0.064
ribose phosphate metabolic process GO:0019693 291 0.064
regulation of microtubule based process GO:0032886 52 0.062
nucleobase containing small molecule metabolic process GO:0055086 352 0.061
chromatin modification GO:0016568 187 0.059
methylation GO:0032259 134 0.056
regulation of organelle organization GO:0033043 289 0.055
cellular amine metabolic process GO:0044106 44 0.053
male meiosis GO:0007140 37 0.053
regulation of cellular ketone metabolic process GO:0010565 66 0.052
nucleotide metabolic process GO:0009117 332 0.052
ribonucleoside triphosphate metabolic process GO:0009199 220 0.051
purine nucleotide metabolic process GO:0006163 302 0.050
nucleoside metabolic process GO:0009116 246 0.050
nucleoside phosphate metabolic process GO:0006753 338 0.050
organic cyclic compound catabolic process GO:1901361 295 0.050
Human
regulation of cytoskeleton organization GO:0051493 122 0.049
purine nucleoside triphosphate metabolic process GO:0009144 226 0.048
nucleoside catabolic process GO:0009164 206 0.048
purine nucleoside metabolic process GO:0042278 241 0.047
carbohydrate derivative catabolic process GO:1901136 231 0.047
aromatic compound catabolic process GO:0019439 286 0.046
Human
chromatin organization GO:0006325 206 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
regulation of cellular component biogenesis GO:0044087 181 0.044
negative regulation of cellular protein metabolic process GO:0032269 247 0.044
response to light stimulus GO:0009416 135 0.043
meiotic nuclear division GO:0007126 115 0.042
spermatogenesis GO:0007283 284 0.041
nucleoside monophosphate metabolic process GO:0009123 85 0.040
germ cell development GO:0007281 185 0.040
organophosphate catabolic process GO:0046434 232 0.040
ribonucleoside metabolic process GO:0009119 245 0.039
purine ribonucleoside metabolic process GO:0046128 241 0.039
purine ribonucleotide catabolic process GO:0009154 208 0.039
purine nucleoside catabolic process GO:0006152 205 0.039
nucleoside triphosphate metabolic process GO:0009141 230 0.039
posttranscriptional regulation of gene expression GO:0010608 155 0.039
purine nucleoside triphosphate catabolic process GO:0009146 203 0.038
ribonucleotide metabolic process GO:0009259 291 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.037
nucleoside triphosphate catabolic process GO:0009143 205 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
cell type specific apoptotic process GO:0097285 268 0.036
mitotic cell cycle process GO:1903047 159 0.036
organonitrogen compound catabolic process GO:1901565 264 0.035
anion transport GO:0006820 177 0.035
ribonucleoside triphosphate catabolic process GO:0009203 199 0.035
development of primary sexual characteristics GO:0045137 143 0.034
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.033
ribonucleotide catabolic process GO:0009261 208 0.033
purine containing compound metabolic process GO:0072521 311 0.033
regulation of nucleotide metabolic process GO:0006140 169 0.033
regulation of transferase activity GO:0051338 263 0.031
negative regulation of organelle organization GO:0010639 90 0.031
regulation of centriole replication GO:0046599 1 0.030
regulation of kinase activity GO:0043549 249 0.030
nucleotide catabolic process GO:0009166 217 0.029
gonad development GO:0008406 141 0.029
purine containing compound catabolic process GO:0072523 213 0.029
dna replication independent nucleosome assembly GO:0006336 1 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
ribonucleoside catabolic process GO:0042454 206 0.028
protein maturation GO:0051604 176 0.028
cell division GO:0051301 120 0.028
macromolecule catabolic process GO:0009057 281 0.027
Human
nucleoside phosphate catabolic process GO:1901292 222 0.027
regulation of purine nucleotide metabolic process GO:1900542 169 0.027
negative regulation of cell cycle GO:0045786 123 0.027
response to uv GO:0009411 44 0.026
macromolecule methylation GO:0043414 120 0.026
nucleoside monophosphate catabolic process GO:0009125 59 0.026
ubiquitin dependent protein catabolic process GO:0006511 129 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
purine nucleotide catabolic process GO:0006195 211 0.026
regulation of mitotic cell cycle GO:0007346 126 0.025
chromosome segregation GO:0007059 48 0.025
organelle assembly GO:0070925 177 0.025
apoptotic signaling pathway GO:0097190 306 0.025
regulation of cell division GO:0051302 76 0.025
mitotic nuclear division GO:0007067 48 0.025
cellular lipid metabolic process GO:0044255 323 0.025
meiosis i GO:0007127 60 0.025
regulation of protein kinase activity GO:0045859 232 0.025
dna repair GO:0006281 107 0.025
Human
peptidyl amino acid modification GO:0018193 336 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
regulation of hydrolase activity GO:0051336 246 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
leukocyte differentiation GO:0002521 342 0.024
cellular protein catabolic process GO:0044257 155 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
cellular response to abiotic stimulus GO:0071214 56 0.024
lipid biosynthetic process GO:0008610 179 0.023
positive regulation of kinase activity GO:0033674 155 0.023
cation transport GO:0006812 399 0.023
atp metabolic process GO:0046034 75 0.023
heterocycle catabolic process GO:0046700 280 0.023
Human
response to organonitrogen compound GO:0010243 246 0.023
positive regulation of apoptotic process GO:0043065 217 0.022
maintenance of location GO:0051235 89 0.022
chromosome organization involved in meiosis GO:0070192 39 0.022
regulation of nucleoside metabolic process GO:0009118 130 0.022
cellular response to organic cyclic compound GO:0071407 87 0.022
spermatid differentiation GO:0048515 115 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
microtubule organizing center organization GO:0031023 28 0.021
regulation of cell activation GO:0050865 289 0.021
protein catabolic process GO:0030163 221 0.021
regulation of cellular response to stress GO:0080135 159 0.021
homeostasis of number of cells GO:0048872 210 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
positive regulation of cytoskeleton organization GO:0051495 49 0.021
transmembrane transport GO:0055085 412 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
ion transmembrane transport GO:0034220 361 0.021
cellular response to radiation GO:0071478 28 0.020
regulation of membrane potential GO:0042391 192 0.020
cellular response to lipid GO:0071396 145 0.020
spindle organization GO:0007051 28 0.020
response to ionizing radiation GO:0010212 42 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
atp catabolic process GO:0006200 55 0.020
synapsis GO:0007129 34 0.019
cilium assembly GO:0042384 81 0.019
negative regulation of nuclear division GO:0051784 19 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
positive regulation of protein modification process GO:0031401 299 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
oxidation reduction process GO:0055114 342 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
regulation of response to wounding GO:1903034 189 0.019
ras protein signal transduction GO:0007265 77 0.019
rho protein signal transduction GO:0007266 32 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
response to inorganic substance GO:0010035 96 0.018
leukocyte proliferation GO:0070661 172 0.018
inflammatory response GO:0006954 244 0.018
myeloid cell differentiation GO:0030099 233 0.018
regulation of chromosome organization GO:0033044 83 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
ribonucleoside monophosphate metabolic process GO:0009161 80 0.018
compound eye development GO:0048749 1 0.018
cell adhesion GO:0007155 329 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.018
negative regulation of molecular function GO:0044092 258 0.017
lymphocyte differentiation GO:0030098 242 0.017
protein methylation GO:0006479 81 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
lateral inhibition GO:0046331 1 0.017
immune effector process GO:0002252 321 0.017
regulation of protein processing GO:0070613 96 0.017
protein ubiquitination GO:0016567 171 0.016
regulation of homeostatic process GO:0032844 182 0.016
regulation of protein maturation GO:1903317 96 0.016
heterochromatin organization GO:0070828 4 0.016
actin cytoskeleton organization GO:0030036 220 0.016
positive regulation of cell death GO:0010942 224 0.016
cytokine production GO:0001816 319 0.016
ossification GO:0001503 216 0.016
centrosome cycle GO:0007098 23 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
regulation of protein localization GO:0032880 231 0.016
negative regulation of cell cycle process GO:0010948 69 0.016
regulation of t cell activation GO:0050863 170 0.016
action potential GO:0001508 78 0.016
regulation of mapk cascade GO:0043408 248 0.015
cytoplasmic transport GO:0016482 234 0.015
peptidyl lysine modification GO:0018205 77 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
sister chromatid segregation GO:0000819 20 0.015
mapk cascade GO:0000165 281 0.015
regulation of cell cycle phase transition GO:1901987 77 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
centrosome separation GO:0051299 4 0.015
negative regulation of transferase activity GO:0051348 85 0.015
positive regulation of cell development GO:0010720 237 0.015
protein processing GO:0016485 163 0.015
regulation of protein catabolic process GO:0042176 108 0.015
t cell activation GO:0042110 289 0.015
regulation of cellular protein catabolic process GO:1903362 61 0.015
regulation of secretion GO:0051046 274 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
protein localization to organelle GO:0033365 185 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
lymphocyte proliferation GO:0046651 164 0.015
sensory perception GO:0007600 245 0.015
positive regulation of organelle organization GO:0010638 128 0.015
small molecule biosynthetic process GO:0044283 132 0.014
response to oxidative stress GO:0006979 123 0.014
regulation of neuron differentiation GO:0045664 281 0.014
protein autophosphorylation GO:0046777 61 0.014
regulation of cytokine production GO:0001817 266 0.014
spermatid development GO:0007286 108 0.014
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.014
blood vessel morphogenesis GO:0048514 285 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
regulation of body fluid levels GO:0050878 162 0.014
attachment of spindle microtubules to kinetochore GO:0008608 4 0.014
protein acylation GO:0043543 64 0.014
neural precursor cell proliferation GO:0061351 121 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
response to growth factor GO:0070848 198 0.014
dna packaging GO:0006323 30 0.014
negative regulation of protein modification process GO:0031400 163 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
mitotic sister chromatid segregation GO:0000070 14 0.014
alpha beta t cell activation GO:0046631 91 0.014
muscle tissue development GO:0060537 308 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
stem cell proliferation GO:0072089 117 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
organic anion transport GO:0015711 137 0.013
regulation of secretion by cell GO:1903530 249 0.013
multicellular organismal signaling GO:0035637 91 0.013
transmission of nerve impulse GO:0019226 76 0.013
cellular homeostasis GO:0019725 240 0.013
wnt signaling pathway GO:0016055 188 0.013
membrane organization GO:0061024 245 0.013
response to acid chemical GO:0001101 111 0.013
purine nucleoside monophosphate catabolic process GO:0009128 58 0.013
nitrogen compound transport GO:0071705 271 0.013
skeletal system development GO:0001501 356 0.013
leukocyte apoptotic process GO:0071887 71 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
neural tube formation GO:0001841 108 0.012
muscle cell differentiation GO:0042692 261 0.012
protein secretion GO:0009306 111 0.012
regulation of binding GO:0051098 111 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
cellular response to gamma radiation GO:0071480 4 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
histone modification GO:0016570 159 0.012
protein localization to nucleus GO:0034504 121 0.012
positive regulation of transferase activity GO:0051347 167 0.012
developmental maturation GO:0021700 193 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
intracellular protein transport GO:0006886 204 0.012
carbohydrate metabolic process GO:0005975 230 0.012
stem cell differentiation GO:0048863 268 0.012
divalent metal ion transport GO:0070838 172 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
regulation of microtubule cytoskeleton organization GO:0070507 37 0.012
dendrite development GO:0016358 115 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
female meiosis chromosome segregation GO:0016321 1 0.012
dna endoreduplication GO:0042023 4 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
cellular chemical homeostasis GO:0055082 215 0.012
locomotory behavior GO:0007626 195 0.012
b cell activation GO:0042113 161 0.012
spindle assembly involved in mitosis GO:0090307 4 0.012
positive regulation of gtpase activity GO:0043547 85 0.011
anatomical structure homeostasis GO:0060249 145 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
cilium morphogenesis GO:0060271 102 0.011
forebrain development GO:0030900 302 0.011
sequestering of calcium ion GO:0051208 18 0.011
translation GO:0006412 93 0.011
placenta development GO:0001890 140 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.011
Human
regulation of cell motility GO:2000145 236 0.011
cellularization GO:0007349 1 0.011
rna interference GO:0016246 2 0.011
covalent chromatin modification GO:0016569 163 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
striated muscle tissue development GO:0014706 293 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
regulation of system process GO:0044057 200 0.011
negative regulation of protein maturation GO:1903318 79 0.011
regulation of inflammatory response GO:0050727 147 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
negative regulation of cellular catabolic process GO:0031330 47 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
organelle localization GO:0051640 179 0.011
protein oligomerization GO:0051259 67 0.011
positive regulation of nervous system development GO:0051962 221 0.011
positive regulation of t cell activation GO:0050870 101 0.011
response to organic cyclic compound GO:0014070 198 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
wound healing GO:0042060 157 0.011
skin development GO:0043588 220 0.011
cell maturation GO:0048469 127 0.011
trophoblast giant cell differentiation GO:0060707 15 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of protein complex assembly GO:0043254 83 0.011
t cell differentiation GO:0030217 174 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
centromere complex assembly GO:0034508 3 0.011
dna recombination GO:0006310 92 0.011
Human
response to oxygen levels GO:0070482 62 0.011
regulation of intracellular transport GO:0032386 159 0.010
embryonic epithelial tube formation GO:0001838 130 0.010
negative regulation of protein catabolic process GO:0042177 36 0.010
axoneme assembly GO:0035082 15 0.010
urogenital system development GO:0001655 261 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
regulation of chromatin modification GO:1903308 57 0.010
alpha amino acid metabolic process GO:1901605 59 0.010
positive regulation of protein catabolic process GO:0045732 60 0.010
negative regulation of proteolysis GO:0045861 74 0.010
lipid localization GO:0010876 126 0.010
embryonic placenta development GO:0001892 98 0.010
regulation of hormone levels GO:0010817 211 0.010
neural tube development GO:0021915 160 0.010
mitotic spindle organization GO:0007052 10 0.010
negative regulation of phosphorylation GO:0042326 166 0.010
digestive system development GO:0055123 200 0.010

Rbbp8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.021
cancer DOID:162 0 0.017
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
immune system disease DOID:2914 0 0.015
hematopoietic system disease DOID:74 0 0.015
sensory system disease DOID:0050155 0 0.012
organ system cancer DOID:0050686 0 0.012
thoracic cancer DOID:5093 0 0.011
breast cancer DOID:1612 0 0.010
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010