|
|
dna metabolic process
|
GO:0006259 |
303 |
0.944
|
Fly |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.903
|
Mouse Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.900
|
Fly |
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.883
|
Mouse Worm Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.877
|
Mouse Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.851
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.834
|
Mouse Fly |
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.798
|
Mouse |
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.786
|
Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.783
|
Fly |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.734
|
Mouse Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.715
|
Mouse Fly |
|
|
organelle fission
|
GO:0048285 |
170 |
0.686
|
Fly |
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.678
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.673
|
Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.618
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.612
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.578
|
Human |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.570
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.561
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.555
|
Mouse Fly |
|
|
digestive system development
|
GO:0055123 |
200 |
0.541
|
Mouse Worm |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.537
|
Fly |
|
|
nuclear division
|
GO:0000280 |
158 |
0.514
|
Fly |
|
|
dna endoreduplication
|
GO:0042023 |
4 |
0.501
|
Fly |
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.489
|
Fly |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.486
|
Mouse |
|
|
response to radiation
|
GO:0009314 |
165 |
0.481
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.471
|
|
|
|
regulation of dna replication
|
GO:0006275 |
17 |
0.461
|
Fly |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.450
|
Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.439
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.427
|
Mouse |
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
31 |
0.415
|
Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.412
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.407
|
Mouse |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.399
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
1 |
0.396
|
Mouse |
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.396
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.390
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.389
|
Mouse |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.389
|
Fly |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.381
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.372
|
Mouse |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.370
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.366
|
Mouse Worm |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.363
|
Mouse Worm Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.363
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.351
|
Mouse Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.336
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.331
|
|
|
|
regulation of cell cycle g2 m phase transition
|
GO:1902749 |
10 |
0.330
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.327
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.322
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.321
|
Mouse Fly |
|
|
cellular response to gamma radiation
|
GO:0071480 |
4 |
0.319
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.315
|
Fly |
|
|
regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0000083 |
3 |
0.309
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.305
|
|
|
|
dna replication
|
GO:0006260 |
52 |
0.304
|
Fly |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.301
|
Mouse Fly |
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.297
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.297
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.296
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.280
|
|
|
|
double strand break repair
|
GO:0006302 |
48 |
0.278
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.275
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.273
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.273
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.259
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.257
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.253
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.248
|
Mouse Fly |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.247
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.246
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.244
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.243
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.242
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.238
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.238
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.234
|
Mouse |
|
|
limb development
|
GO:0060173 |
166 |
0.231
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.230
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.227
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.226
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.224
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
14 |
0.223
|
Fly |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.222
|
Worm |
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.221
|
Fly |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.219
|
Fly |
|
|
dna packaging
|
GO:0006323 |
30 |
0.218
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.217
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.216
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.216
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.216
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.213
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.213
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.213
|
Mouse |
|
|
appendage development
|
GO:0048736 |
166 |
0.211
|
|
|
|
embryonic digestive tract development
|
GO:0048566 |
27 |
0.211
|
Worm |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.209
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.208
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.205
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.198
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.197
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.197
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.196
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.193
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.193
|
Fly |
|
|
epidermis development
|
GO:0008544 |
187 |
0.193
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.192
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.190
|
Fly |
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.189
|
Fly |
|
|
regulation of cohesin localization to chromatin
|
GO:0071922 |
1 |
0.189
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.189
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.188
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.187
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.187
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.186
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.186
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.183
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.181
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.178
|
|
|
|
cohesin localization to chromatin
|
GO:0071921 |
1 |
0.178
|
Fly |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.177
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.175
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.173
|
Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.173
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.171
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.166
|
Mouse |
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
49 |
0.165
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.164
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.164
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.160
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.158
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.158
|
Worm |
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.157
|
Mouse |
|
|
meiosis i
|
GO:0007127 |
60 |
0.156
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.155
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.155
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
22 |
0.154
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.152
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.149
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.148
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.148
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.147
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.147
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.146
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.145
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.144
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.144
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.143
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.142
|
|
|
|
spindle localization
|
GO:0051653 |
22 |
0.141
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.141
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.140
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.139
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.139
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.138
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.137
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.137
|
|
|
|
hepatocyte apoptotic process
|
GO:0097284 |
11 |
0.136
|
Mouse |
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.135
|
Mouse Worm |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.134
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.134
|
Worm |
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.134
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.132
|
|
|
|
enucleate erythrocyte differentiation
|
GO:0043353 |
8 |
0.132
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.132
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.130
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.129
|
Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.128
|
Mouse |
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.127
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.127
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.125
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.125
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.124
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.124
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.122
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.122
|
|
|
|
positive regulation of macrophage differentiation
|
GO:0045651 |
5 |
0.122
|
Mouse |
|
|
neural tube development
|
GO:0021915 |
160 |
0.121
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.120
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.119
|
|
|
|
dna conformation change
|
GO:0071103 |
37 |
0.119
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.118
|
|
|
|
regulation of dna binding
|
GO:0051101 |
39 |
0.118
|
Fly |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.118
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.118
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.117
|
Human |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.116
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.116
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
41 |
0.114
|
|
|
|
regulation of mitosis
|
GO:0007088 |
29 |
0.114
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.114
|
|
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
8 |
0.112
|
Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.112
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.112
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.111
|
Mouse |
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.111
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.111
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.110
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.110
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.108
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.108
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.107
|
Mouse |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.107
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.105
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.105
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.104
|
Mouse Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.103
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
19 |
0.103
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.103
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.103
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.102
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.102
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.102
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.102
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.102
|
Mouse |
|
|
ear development
|
GO:0043583 |
200 |
0.101
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.101
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.100
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
19 |
0.098
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.098
|
Mouse |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.097
|
Mouse |
|
|
t cell activation
|
GO:0042110 |
289 |
0.097
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.096
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.096
|
Mouse |
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.096
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
3 |
0.096
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.095
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.094
|
|
|
|
neuron maturation
|
GO:0042551 |
29 |
0.094
|
Mouse |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.094
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.093
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.093
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.093
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.093
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.093
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.092
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.091
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.091
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.091
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.091
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.090
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.090
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.089
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.089
|
|
|
|
protein localization to chromatin
|
GO:0071168 |
3 |
0.089
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.088
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.088
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.087
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.087
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.087
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.086
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.086
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.085
|
Mouse |
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.085
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.085
|
Mouse Fly |
|
|
neural tube formation
|
GO:0001841 |
108 |
0.084
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.084
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.084
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.084
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.083
|
Mouse |
|
|
spermatid development
|
GO:0007286 |
108 |
0.083
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.083
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.082
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.082
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.082
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.082
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.081
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.081
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.081
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.081
|
|
|
|
mitotic cell cycle arrest
|
GO:0071850 |
4 |
0.081
|
Worm |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.081
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.080
|
|
|
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.080
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
11 |
0.080
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.079
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.079
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.078
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.078
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.078
|
|
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.078
|
Mouse |
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.077
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.077
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.077
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.076
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.076
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
19 |
0.076
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.075
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.075
|
|
|
|
chromosome organization involved in meiosis
|
GO:0070192 |
39 |
0.075
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.074
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.074
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.074
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.073
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.072
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.072
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.071
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.071
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.071
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.071
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.071
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.070
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.070
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.070
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.070
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.069
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.069
|
Worm |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.069
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.069
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.069
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.068
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.068
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.067
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.067
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.066
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.066
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.066
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.066
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.066
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.066
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.066
|
|
|
|
base excision repair
|
GO:0006284 |
9 |
0.065
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.065
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.065
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.064
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.064
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.064
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.064
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.064
|
|
|
|
histone methylation
|
GO:0016571 |
71 |
0.064
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.064
|
Mouse Fly |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.064
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.064
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.063
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.063
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.063
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.063
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.063
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.062
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
35 |
0.062
|
Mouse Fly |
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.061
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.061
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.061
|
Mouse |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.061
|
|
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.060
|
Worm |
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.060
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.060
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.060
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.059
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
18 |
0.059
|
Mouse Fly |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.059
|
Fly |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.059
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.059
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.058
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.058
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.058
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.058
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.057
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.057
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.057
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
3 |
0.057
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.057
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.057
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.056
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.056
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.056
|
|
|
|
dna catabolic process
|
GO:0006308 |
19 |
0.055
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.055
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.054
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.054
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.054
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.054
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.054
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.054
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.053
|
|
|
|
metaphase plate congression
|
GO:0051310 |
2 |
0.053
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.053
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.053
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.053
|
|
|
|
apoptotic dna fragmentation
|
GO:0006309 |
7 |
0.053
|
|
|
|
intestinal epithelial structure maintenance
|
GO:0060729 |
4 |
0.053
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.052
|
Worm |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.052
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.052
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.052
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.052
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.051
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.050
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.050
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.050
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.050
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.050
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.050
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.050
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.050
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
3 |
0.050
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.049
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.049
|
|
|
|
negative regulation of nuclear division
|
GO:0051784 |
19 |
0.049
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.049
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.049
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.049
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.048
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
21 |
0.048
|
Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.048
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.047
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.047
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.047
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.047
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
12 |
0.047
|
Fly |
|
|
cartilage development
|
GO:0051216 |
140 |
0.047
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.047
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.046
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.046
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.046
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.046
|
|
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
9 |
0.046
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.046
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.046
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.046
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.045
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.045
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
31 |
0.045
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.045
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.045
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.045
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.044
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.044
|
|
|
|
apoptotic nuclear changes
|
GO:0030262 |
9 |
0.044
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.044
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
19 |
0.044
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.044
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.043
|
|
|
|
cell aging
|
GO:0007569 |
35 |
0.043
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
18 |
0.043
|
Mouse Fly |
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
15 |
0.043
|
|
|
|
microtubule cytoskeleton organization involved in mitosis
|
GO:1902850 |
4 |
0.042
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.042
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.042
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.042
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.042
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.042
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.041
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.041
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.041
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.041
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.041
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.041
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.041
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.041
|
Human |
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.040
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.040
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.040
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.040
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.040
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.040
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.039
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.039
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.039
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.039
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.039
|
|
|
|
genitalia development
|
GO:0048806 |
37 |
0.039
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.039
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.039
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.039
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.039
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.039
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.039
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.039
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.039
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.039
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
4 |
0.038
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.038
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.038
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.038
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.038
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
3 |
0.038
|
|
|
|
protein localization to chromosome centromeric region
|
GO:0071459 |
1 |
0.038
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.038
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.038
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.038
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.037
|
|
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
9 |
0.037
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.037
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.037
|
|
|
|
toxin transport
|
GO:1901998 |
38 |
0.037
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.037
|
Mouse |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.037
|
|
