|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.881
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.747
|
Fly |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.738
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.707
|
Mouse |
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.669
|
Mouse |
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.653
|
Mouse |
|
|
regulation of engulfment of apoptotic cell
|
GO:1901074 |
2 |
0.621
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.610
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.601
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.590
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.582
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.580
|
Fly |
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.579
|
Mouse Worm Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.571
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.562
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.553
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.545
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.544
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.526
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.524
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.504
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.502
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.495
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.471
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.467
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.464
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.448
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.437
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.433
|
Mouse |
|
|
appendage development
|
GO:0048736 |
166 |
0.431
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.429
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.398
|
|
|
|
mitotic sister chromatid cohesion
|
GO:0007064 |
1 |
0.377
|
Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.376
|
Mouse |
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.367
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.366
|
Mouse |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.342
|
Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.337
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.336
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.334
|
Mouse |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.331
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.329
|
Mouse |
|
|
limb development
|
GO:0060173 |
166 |
0.328
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.316
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.310
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.305
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.299
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.299
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.295
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.293
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.284
|
Fly |
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.282
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.279
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.269
|
Fly |
|
|
histone modification
|
GO:0016570 |
159 |
0.268
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.268
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.262
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.261
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.255
|
|
|
|
cohesin localization to chromatin
|
GO:0071921 |
1 |
0.255
|
Fly |
|
|
regulation of cohesin localization to chromatin
|
GO:0071922 |
1 |
0.255
|
Fly |
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.254
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.253
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.251
|
Worm |
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.251
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.232
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
1 |
0.231
|
Mouse |
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.228
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.227
|
Mouse |
|
|
rhythmic process
|
GO:0048511 |
174 |
0.226
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.224
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.215
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.214
|
Mouse Fly |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.212
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.210
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.209
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.208
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.208
|
Mouse |
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.207
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.206
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.204
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.202
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.202
|
Mouse |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.200
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.199
|
Mouse Fly |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.199
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.198
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.197
|
Mouse Fly |
|
|
gland development
|
GO:0048732 |
330 |
0.197
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.195
|
|
|
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.190
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.189
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.188
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.186
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.183
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.182
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.182
|
Mouse |
|
|
cellular glucan metabolic process
|
GO:0006073 |
32 |
0.180
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.180
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.180
|
Mouse |
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.180
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.178
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.177
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.177
|
Mouse |
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.177
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.173
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.172
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.171
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.170
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.170
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
44 |
0.165
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.162
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.159
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.155
|
Mouse Fly |
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.155
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.155
|
|
|
|
hexose biosynthetic process
|
GO:0019319 |
39 |
0.155
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.154
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.153
|
Mouse Fly |
|
|
positive regulation of macrophage differentiation
|
GO:0045651 |
5 |
0.152
|
Mouse |
|
|
regionalization
|
GO:0003002 |
337 |
0.152
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.152
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.151
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.151
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.150
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.150
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.149
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.148
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.148
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.147
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.147
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.147
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.144
|
Mouse Fly |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.143
|
|
|
|
growth plate cartilage chondrocyte development
|
GO:0003431 |
3 |
0.140
|
|
|
|
cartilage condensation
|
GO:0001502 |
18 |
0.140
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.140
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.140
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.138
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.136
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.135
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.135
|
Worm |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.133
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.132
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.132
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.131
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.131
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.130
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.129
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.128
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.127
|
|
|
|
cholesterol homeostasis
|
GO:0042632 |
44 |
0.126
|
|
|
|
histone methylation
|
GO:0016571 |
71 |
0.125
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.125
|
Mouse |
|
|
cerebellum development
|
GO:0021549 |
77 |
0.124
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.122
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.122
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.122
|
Mouse Fly |
|
|
harderian gland development
|
GO:0070384 |
2 |
0.122
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.121
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.119
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.119
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.117
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.117
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.117
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.116
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.115
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.115
|
|
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.115
|
Worm |
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.114
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.114
|
|
|
|
glucocorticoid mediated signaling pathway
|
GO:0043402 |
3 |
0.113
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.112
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.111
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.111
|
|
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.111
|
Mouse |
|
|
neural tube development
|
GO:0021915 |
160 |
0.109
|
|
|
|
gluconeogenesis
|
GO:0006094 |
39 |
0.109
|
|
|
|
regulation of dna binding
|
GO:0051101 |
39 |
0.109
|
Fly |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.109
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.108
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.106
|
Fly |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.106
|
|
|
|
chromatin silencing
|
GO:0006342 |
15 |
0.105
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.105
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.105
|
|
|
|
dna modification
|
GO:0006304 |
50 |
0.104
|
|
|
|
bone mineralization
|
GO:0030282 |
54 |
0.104
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.103
|
|
|
|
memory
|
GO:0007613 |
58 |
0.102
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.102
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.101
|
|
|
|
chondrocyte hypertrophy
|
GO:0003415 |
4 |
0.101
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.101
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.101
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.100
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.100
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.099
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.099
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.097
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.096
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.096
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.095
|
Fly |
|
|
response to insulin
|
GO:0032868 |
100 |
0.095
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.094
|
Worm |
|
|
germ cell development
|
GO:0007281 |
185 |
0.094
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.092
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.091
|
Mouse Fly |
|
|
peptidyl lysine methylation
|
GO:0018022 |
29 |
0.091
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.090
|
Mouse |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.089
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.089
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.089
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.089
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.089
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.089
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.088
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.088
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.087
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.087
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.087
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.086
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.086
|
Mouse Fly |
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.086
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.086
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.085
|
Fly |
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
35 |
0.085
|
Mouse Fly |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.084
|
Fly |
|
|
monosaccharide biosynthetic process
|
GO:0046364 |
44 |
0.084
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.084
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.083
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.083
|
|
|
|
lysosome organization
|
GO:0007040 |
21 |
0.083
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.083
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.082
|
|
|
|
positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway
|
GO:1902237 |
3 |
0.082
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.082
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.082
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.081
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.081
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.081
|
|
|
|
regulation of gluconeogenesis
|
GO:0006111 |
30 |
0.081
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.081
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.080
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.079
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.078
|
Fly |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.078
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.078
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.078
|
|
|
|
protein localization to chromatin
|
GO:0071168 |
3 |
0.077
|
Fly |
|
|
germ line stem cell division
|
GO:0042078 |
2 |
0.077
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.077
|
|
|
|
positive regulation of mitotic sister chromatid separation
|
GO:1901970 |
2 |
0.076
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.076
|
|
|
|
germinal center formation
|
GO:0002467 |
16 |
0.076
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.076
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.076
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.076
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.076
|
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.075
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.075
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.075
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.074
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.074
|
Worm |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.074
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.074
|
|
|
|
alcohol catabolic process
|
GO:0046164 |
16 |
0.073
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.072
|
|
|
|
apoptotic cell clearance
|
GO:0043277 |
17 |
0.072
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.072
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.071
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.071
|
Mouse Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.071
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.071
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.070
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.069
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.069
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.068
|
Fly |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.068
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.068
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
71 |
0.068
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.068
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.067
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.067
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.067
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.067
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.067
|
|
|
|
telomere maintenance
|
GO:0000723 |
19 |
0.066
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.065
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.065
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
31 |
0.065
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.065
|
Mouse |
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.065
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.064
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.064
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.064
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
42 |
0.064
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.063
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.063
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.063
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.063
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.062
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
33 |
0.062
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.061
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.061
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.061
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.061
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.061
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.060
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.060
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.060
|
|
|
|
positive regulation of engulfment of apoptotic cell
|
GO:1901076 |
1 |
0.060
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.060
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
12 |
0.060
|
Fly |
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.059
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.059
|
Mouse Fly |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.059
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
17 |
0.059
|
Worm |
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.059
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.058
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.058
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
46 |
0.058
|
|
|
|
artery development
|
GO:0060840 |
53 |
0.058
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.058
|
|
|
|
regulation of histone methylation
|
GO:0031060 |
30 |
0.057
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.057
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.057
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
34 |
0.056
|
|
|
|
sterol homeostasis
|
GO:0055092 |
45 |
0.056
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.056
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.055
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.055
|
|
|
|
negative regulation of chondrocyte differentiation
|
GO:0032331 |
13 |
0.055
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.055
|
Fly |
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.054
|
Mouse Worm |
|
|
mitochondrion localization
|
GO:0051646 |
9 |
0.054
|
|
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.054
|
|
|
|
negative regulation of type b pancreatic cell apoptotic process
|
GO:2000675 |
3 |
0.054
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.054
|
Mouse Worm |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.053
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.052
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.052
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.052
|
Human |
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.052
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.052
|
Fly |
|
|
cartilage development
|
GO:0051216 |
140 |
0.052
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.052
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.052
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.051
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.051
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.051
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.051
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.051
|
|
|
|
organic hydroxy compound catabolic process
|
GO:1901616 |
25 |
0.050
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
18 |
0.050
|
Mouse Fly |
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.050
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.050
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.050
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
47 |
0.050
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.049
|
|
|
|
hepatocyte apoptotic process
|
GO:0097284 |
11 |
0.049
|
Mouse |
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.049
|
|
|
|
cell aging
|
GO:0007569 |
35 |
0.049
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
9 |
0.049
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.049
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.049
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
18 |
0.048
|
Mouse Fly |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.048
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.048
|
|
|
|
organic acid catabolic process
|
GO:0016054 |
51 |
0.048
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.048
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.047
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.047
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.047
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.047
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.047
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.046
|
|
|
|
cellular response to retinoic acid
|
GO:0071300 |
25 |
0.046
|
|
|
|
intracellular distribution of mitochondria
|
GO:0048312 |
1 |
0.046
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.046
|
|
|
|
negative regulation of cell aging
|
GO:0090344 |
5 |
0.046
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.046
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.046
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.046
|
|
|
|
positive regulation of histone methylation
|
GO:0031062 |
16 |
0.046
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.046
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.045
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.045
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.045
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.045
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.045
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.045
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.045
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.045
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.045
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.045
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.044
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.044
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
34 |
0.044
|
|
|
|
enucleate erythrocyte differentiation
|
GO:0043353 |
8 |
0.044
|
Mouse |
|
|
respiratory system development
|
GO:0060541 |
190 |
0.044
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.044
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.044
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.044
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.043
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.043
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.043
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.043
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.042
|
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
32 |
0.042
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.042
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.042
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.042
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.042
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.041
|
|
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
32 |
0.041
|
|
|
|
cerebellum morphogenesis
|
GO:0021587 |
42 |
0.041
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.041
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.041
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.041
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.041
|
Mouse |
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.041
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.041
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.041
|
|
|
|
regulation of cell growth involved in cardiac muscle cell development
|
GO:0061050 |
3 |
0.041
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.040
|
|
|
|
endochondral bone growth
|
GO:0003416 |
19 |
0.040
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.040
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.040
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.040
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.040
|
|
|
|
histone h4 k16 acetylation
|
GO:0043984 |
3 |
0.040
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.040
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.040
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.040
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.039
|
|
|
|
positive regulation of phagocytosis engulfment
|
GO:0060100 |
3 |
0.039
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.039
|
Mouse Fly |
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
13 |
0.039
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.039
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.039
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.038
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.038
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.038
|
|
|
|
intestinal epithelial structure maintenance
|
GO:0060729 |
4 |
0.038
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.038
|
|
|
|
mitochondrion transport along microtubule
|
GO:0047497 |
3 |
0.038
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.037
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
14 |
0.037
|
Human |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.037
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.037
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.037
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.037
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.036
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.036
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.036
|
|
|
|
cellular response to glucose stimulus
|
GO:0071333 |
45 |
0.036
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.036
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.036
|
Fly |
|
|
cellular response to nitric oxide
|
GO:0071732 |
4 |
0.036
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.036
|
Human |
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.035
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.035
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.035
|
Worm |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.035
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.035
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.035
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.035
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.035
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.035
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.035
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
4 |
0.035
|
|
|
|
cell proliferation in hindbrain
|
GO:0021534 |
10 |
0.035
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.035
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.034
|
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
53 |
0.034
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.034
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.034
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.034
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.034
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.034
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.034
|
|
|
|
steroid hormone mediated signaling pathway
|
GO:0043401 |
6 |
0.034
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.034
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
23 |
0.034
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.034
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.034
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.034
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.034
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.034
|
|
|
|
phospholipid transfer to membrane
|
GO:0006649 |
2 |
0.033
|
|
