Mus musculus

17 known processes

Rdx

radixin

(Aliases: AA516625)

Rdx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organophosphate catabolic process GO:0046434 232 0.466
cell adhesion GO:0007155 329 0.270
regulation of cell cycle GO:0051726 281 0.218
Fly
establishment of rna localization GO:0051236 18 0.216
axonogenesis GO:0007409 274 0.206
Fly
endomembrane system organization GO:0010256 147 0.189
Worm
dephosphorylation GO:0016311 129 0.175
nucleotide catabolic process GO:0009166 217 0.174
purine ribonucleoside catabolic process GO:0046130 205 0.171
regulation of cell substrate adhesion GO:0010810 73 0.168
cell division GO:0051301 120 0.166
Fly
wnt signaling pathway GO:0016055 188 0.137
purine nucleoside metabolic process GO:0042278 241 0.126
regulation of cell adhesion GO:0030155 154 0.119
mitotic cell cycle GO:0000278 195 0.116
Fly
nucleoside phosphate catabolic process GO:1901292 222 0.112
membrane organization GO:0061024 245 0.106
Worm
negative regulation of protein metabolic process GO:0051248 282 0.105
Mouse
purine nucleotide catabolic process GO:0006195 211 0.105
purine nucleoside catabolic process GO:0006152 205 0.103
nucleobase containing small molecule metabolic process GO:0055086 352 0.101
nucleoside triphosphate metabolic process GO:0009141 230 0.099
purine ribonucleotide catabolic process GO:0009154 208 0.098
nucleoside catabolic process GO:0009164 206 0.090
organelle localization GO:0051640 179 0.090
Fly
nucleoside triphosphate catabolic process GO:0009143 205 0.087
organonitrogen compound catabolic process GO:1901565 264 0.086
neuron projection guidance GO:0097485 141 0.086
Fly
ras protein signal transduction GO:0007265 77 0.086
purine ribonucleotide metabolic process GO:0009150 290 0.086
gtp catabolic process GO:0006184 143 0.085
glycosyl compound catabolic process GO:1901658 206 0.083
hematopoietic progenitor cell differentiation GO:0002244 143 0.083
purine ribonucleoside metabolic process GO:0046128 241 0.082
regulation of cell motility GO:2000145 236 0.081
multicellular organism growth GO:0035264 161 0.081
sensory organ morphogenesis GO:0090596 242 0.079
Fly
cell matrix adhesion GO:0007160 68 0.078
establishment of organelle localization GO:0051656 122 0.077
Fly
blood vessel morphogenesis GO:0048514 285 0.076
positive regulation of cell cycle process GO:0090068 61 0.073
negative regulation of phosphorus metabolic process GO:0010563 184 0.073
Mouse
mitochondrion transport along microtubule GO:0047497 3 0.072
nitrogen compound transport GO:0071705 271 0.070
posttranscriptional gene silencing GO:0016441 10 0.068
purine nucleoside triphosphate catabolic process GO:0009146 203 0.067
rna interference GO:0016246 2 0.066
purine nucleotide metabolic process GO:0006163 302 0.066
cell junction assembly GO:0034329 52 0.065
carbohydrate derivative catabolic process GO:1901136 231 0.064
chemotaxis GO:0006935 247 0.062
Fly
embryonic organ morphogenesis GO:0048562 276 0.062
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.061
synaptic transmission GO:0007268 329 0.060
rna splicing GO:0008380 54 0.059
purine nucleoside triphosphate metabolic process GO:0009144 226 0.059
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.058
cellular nitrogen compound catabolic process GO:0044270 280 0.058
glial cell differentiation GO:0010001 131 0.058
regulation of cell cycle phase transition GO:1901987 77 0.057
regulation of actin cytoskeleton organization GO:0032956 84 0.056
Fly
cytoplasmic transport GO:0016482 234 0.056
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 7 0.056
small gtpase mediated signal transduction GO:0007264 97 0.054
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.053
regulation of mitotic cell cycle GO:0007346 126 0.053
Fly
chromosome segregation GO:0007059 48 0.053
Fly
regulation of membrane potential GO:0042391 192 0.052
Fly
regulation of cell activation GO:0050865 289 0.050
homeostasis of number of cells GO:0048872 210 0.049
negative regulation of protein modification process GO:0031400 163 0.049
Mouse
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.049
negative regulation of cell cycle process GO:0010948 69 0.048
negative regulation of protein phosphorylation GO:0001933 126 0.048
Mouse
establishment of mitochondrion localization GO:0051654 4 0.047
positive regulation of cell activation GO:0050867 158 0.045
negative regulation of molecular function GO:0044092 258 0.045
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.043
Mouse
negative regulation of immune system process GO:0002683 209 0.043
positive regulation of cell substrate adhesion GO:0010811 47 0.042
ribonucleotide catabolic process GO:0009261 208 0.042
stem cell development GO:0048864 219 0.042
nucleotide metabolic process GO:0009117 332 0.041
negative regulation of cell cycle GO:0045786 123 0.041
spermatid development GO:0007286 108 0.040
organic cyclic compound catabolic process GO:1901361 295 0.040
multicellular organismal homeostasis GO:0048871 164 0.040
regulation of cell cycle process GO:0010564 160 0.040
Fly
skin development GO:0043588 220 0.039
learning or memory GO:0007611 148 0.039
ribose phosphate metabolic process GO:0019693 291 0.038
negative regulation of mitotic cell cycle GO:0045930 58 0.038
rho protein signal transduction GO:0007266 32 0.038
single organismal cell cell adhesion GO:0016337 131 0.037
activation of immune response GO:0002253 138 0.037
g1 s transition of mitotic cell cycle GO:0000082 57 0.037
negative regulation of cell motility GO:2000146 61 0.037
cell substrate adhesion GO:0031589 130 0.037
negative regulation of phosphorylation GO:0042326 166 0.037
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.037
regulation of cell migration GO:0030334 219 0.036
sensory perception GO:0007600 245 0.036
endocytosis GO:0006897 168 0.035
Mouse Worm Fly
detection of abiotic stimulus GO:0009582 60 0.035
guanosine containing compound metabolic process GO:1901068 144 0.034
circulatory system process GO:0003013 197 0.034
ribonucleoside triphosphate metabolic process GO:0009199 220 0.034
positive regulation of cell adhesion GO:0045785 80 0.033
regulation of wnt signaling pathway GO:0030111 123 0.033
purine containing compound catabolic process GO:0072523 213 0.033
translation GO:0006412 93 0.032
mitotic cell cycle process GO:1903047 159 0.032
Fly
neuromuscular process controlling balance GO:0050885 59 0.032
spermatid differentiation GO:0048515 115 0.031
detection of external stimulus GO:0009581 61 0.031
t cell receptor signaling pathway GO:0050852 46 0.031
regulation of receptor biosynthetic process GO:0010869 2 0.031
regulation of organelle organization GO:0033043 289 0.030
Fly
ribonucleotide metabolic process GO:0009259 291 0.030
regulation of mapk cascade GO:0043408 248 0.029
Mouse
3 utr mediated mrna stabilization GO:0070935 2 0.029
detection of mechanical stimulus GO:0050982 27 0.029
angiogenesis GO:0001525 201 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
gene silencing GO:0016458 38 0.029
positive regulation of cell migration GO:0030335 109 0.028
cell cell junction organization GO:0045216 72 0.028
Mouse
aromatic compound catabolic process GO:0019439 286 0.028
ribonucleoside catabolic process GO:0042454 206 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
Mouse
cellular component assembly involved in morphogenesis GO:0010927 139 0.027
Worm
ribonucleoprotein complex subunit organization GO:0071826 28 0.027
regulation of mitotic cell cycle phase transition GO:1901990 73 0.027
mitotic cytokinesis GO:0000281 4 0.026
dna metabolic process GO:0006259 303 0.026
blood circulation GO:0008015 195 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
regulation of ras gtpase activity GO:0032318 88 0.026
cellularization GO:0007349 1 0.025
alcohol metabolic process GO:0006066 116 0.025
regulation of response to wounding GO:1903034 189 0.025
transmission of nerve impulse GO:0019226 76 0.025
negative regulation of intracellular signal transduction GO:1902532 167 0.025
Mouse
negative regulation of kinase activity GO:0033673 81 0.025
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.025
Fly
male gamete generation GO:0048232 285 0.025
rna transport GO:0050658 18 0.025
stem cell maintenance GO:0019827 130 0.024
positive regulation of gtpase activity GO:0043547 85 0.024
lymphocyte differentiation GO:0030098 242 0.024
regulation of purine nucleotide catabolic process GO:0033121 122 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
myeloid leukocyte differentiation GO:0002573 119 0.024
positive regulation of cell cycle GO:0045787 92 0.024
immune response activating signal transduction GO:0002757 116 0.024
purine containing compound metabolic process GO:0072521 311 0.023
gliogenesis GO:0042063 141 0.023
protein localization to membrane GO:0072657 108 0.023
Worm
protein localization to plasma membrane GO:0072659 57 0.023
Worm
cognition GO:0050890 149 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.023
heterocycle catabolic process GO:0046700 280 0.023
cellular polysaccharide catabolic process GO:0044247 5 0.023
posttranscriptional gene silencing by rna GO:0035194 10 0.023
wound healing GO:0042060 157 0.022
dna repair GO:0006281 107 0.022
cellular lipid metabolic process GO:0044255 323 0.022
sister chromatid segregation GO:0000819 20 0.022
Fly
positive regulation of mitotic cell cycle GO:0045931 41 0.022
translational initiation GO:0006413 24 0.022
ribonucleoside monophosphate metabolic process GO:0009161 80 0.022
cell cycle g1 s phase transition GO:0044843 57 0.021
establishment of vesicle localization GO:0051650 81 0.021
regulation of translation GO:0006417 71 0.021
regulation of receptor activity GO:0010469 41 0.021
epidermis development GO:0008544 187 0.021
forebrain development GO:0030900 302 0.021
Mouse
positive regulation of gtp catabolic process GO:0033126 85 0.021
fertilization GO:0009566 127 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
limb morphogenesis GO:0035108 149 0.021
negative regulation of wnt signaling pathway GO:0030178 73 0.021
negative regulation of cell migration GO:0030336 59 0.021
mapk cascade GO:0000165 281 0.020
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.020
cell junction organization GO:0034330 77 0.020
Mouse
negative regulation of cell cycle phase transition GO:1901988 48 0.020
ribonucleoside monophosphate catabolic process GO:0009158 57 0.020
negative regulation of chromatin silencing GO:0031936 1 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
single organism cell adhesion GO:0098602 156 0.020
photoreceptor cell maintenance GO:0045494 19 0.020
leukocyte migration GO:0050900 124 0.020
germ cell development GO:0007281 185 0.020
Fly
renal system development GO:0072001 225 0.020
regulation of protein kinase activity GO:0045859 232 0.020
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.019
inner ear receptor cell differentiation GO:0060113 61 0.019
neuromuscular process GO:0050905 99 0.019
positive regulation of secretion by cell GO:1903532 114 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.019
organelle fission GO:0048285 170 0.019
Fly
actin cytoskeleton organization GO:0030036 220 0.019
Worm Fly
positive regulation of cell motility GO:2000147 116 0.019
positive regulation of cell cycle g1 s phase transition GO:1902808 9 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
actin filament organization GO:0007015 113 0.018
Worm
nucleobase containing compound transport GO:0015931 27 0.018
intracellular distribution of mitochondria GO:0048312 1 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
Fly
multi multicellular organism process GO:0044706 109 0.018
Fly
negative regulation of mapk cascade GO:0043409 65 0.018
Mouse
male anatomical structure morphogenesis GO:0090598 4 0.018
gene silencing by rna GO:0031047 19 0.018
meiotic nuclear division GO:0007126 115 0.018
memory GO:0007613 58 0.018
lung development GO:0030324 164 0.018
gonad development GO:0008406 141 0.017
mitochondrion distribution GO:0048311 4 0.017
plasma membrane organization GO:0007009 90 0.017
Worm
rna localization GO:0006403 23 0.017
plus end directed vesicle transport along microtubule GO:0072383 2 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
positive regulation of potassium ion transport GO:0043268 3 0.017
positive regulation of secretion GO:0051047 130 0.017
maintenance of location in cell GO:0051651 24 0.017
myeloid cell homeostasis GO:0002262 114 0.017
negative regulation of translation GO:0017148 22 0.016
maintenance of location GO:0051235 89 0.016
mitotic nuclear division GO:0007067 48 0.016
Fly
cytoskeleton dependent intracellular transport GO:0030705 50 0.016
sensory perception of sound GO:0007605 97 0.016
nucleoside metabolic process GO:0009116 246 0.016
meiotic cell cycle GO:0051321 122 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
cytokinetic process GO:0032506 2 0.016
Fly
proteasomal protein catabolic process GO:0010498 98 0.016
Fly
microtubule based transport GO:0010970 50 0.016
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.016
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.015
rab protein signal transduction GO:0032482 1 0.015
actomyosin structure organization GO:0031032 56 0.015
Worm
intracellular protein transport GO:0006886 204 0.015
regulation of cellular component size GO:0032535 121 0.015
atp metabolic process GO:0046034 75 0.015
regulation of kinase activity GO:0043549 249 0.015
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.015
meiotic cell cycle process GO:1903046 77 0.015
immune response regulating signaling pathway GO:0002764 125 0.015
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.015
atp catabolic process GO:0006200 55 0.015
cellular amino acid metabolic process GO:0006520 103 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.014
early endosome to late endosome transport GO:0045022 2 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
Mouse
mrna metabolic process GO:0016071 84 0.014
b cell activation GO:0042113 161 0.014
regulation of neuron differentiation GO:0045664 281 0.014
small molecule biosynthetic process GO:0044283 132 0.014
positive regulation of g1 s transition of mitotic cell cycle GO:1900087 9 0.014
regulation of transferase activity GO:0051338 263 0.014
Mouse
regulation of blood pressure GO:0008217 93 0.014
tissue homeostasis GO:0001894 115 0.014
amino acid transport GO:0006865 61 0.014
positive regulation of growth GO:0045927 104 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
Fly
sperm individualization GO:0007291 1 0.013
epithelial cell development GO:0002064 159 0.013
Human
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.013
gtp metabolic process GO:0046039 144 0.013
cell chemotaxis GO:0060326 81 0.013
regulation of cell cycle g1 s phase transition GO:1902806 35 0.013
protein maturation GO:0051604 176 0.013
inositol phosphate catabolic process GO:0071545 4 0.013
regulation of hydrolase activity GO:0051336 246 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
nuclear export GO:0051168 34 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
Fly
respiratory tube development GO:0030323 167 0.013
regulation of protein localization GO:0032880 231 0.013
Mouse
leukocyte differentiation GO:0002521 342 0.013
renal system process involved in regulation of blood volume GO:0001977 4 0.013
embryonic limb morphogenesis GO:0030326 126 0.013
regulation of actin filament based process GO:0032970 99 0.013
Fly
actin filament bundle assembly GO:0051017 40 0.013
exocytosis GO:0006887 121 0.013
apoptotic signaling pathway GO:0097190 306 0.013
nucleus localization GO:0051647 20 0.013
t cell differentiation GO:0030217 174 0.013
vesicle organization GO:0016050 60 0.013
regulation of gtp catabolic process GO:0033124 113 0.013
regulation of multi organism process GO:0043900 111 0.012
respiratory system development GO:0060541 190 0.012
detection of stimulus involved in sensory perception GO:0050906 44 0.012
blastocyst development GO:0001824 80 0.012
hemostasis GO:0007599 78 0.012
sensory perception of light stimulus GO:0050953 54 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
transmembrane transport GO:0055085 412 0.012
granulocyte migration GO:0097530 43 0.012
cell recognition GO:0008037 83 0.012
response to organonitrogen compound GO:0010243 246 0.012
cell cycle switching GO:0060184 1 0.012
inner ear morphogenesis GO:0042472 101 0.012
stem cell differentiation GO:0048863 268 0.012
regulation of glomerular filtration GO:0003093 3 0.012
positive regulation of ras gtpase activity GO:0032320 65 0.012
neural precursor cell proliferation GO:0061351 121 0.012
Mouse
macromolecule catabolic process GO:0009057 281 0.012
Fly
oligodendrocyte differentiation GO:0048709 53 0.012
ameboidal type cell migration GO:0001667 128 0.012
mitotic g2 dna damage checkpoint GO:0007095 8 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
protein localization to organelle GO:0033365 185 0.012
Mouse
nuclear division GO:0000280 158 0.011
Fly
detection of stimulus GO:0051606 84 0.011
ear morphogenesis GO:0042471 118 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
glycerolipid metabolic process GO:0046486 122 0.011
positive regulation of rab gtpase activity GO:0032851 7 0.011
cellular protein catabolic process GO:0044257 155 0.011
Fly
axon guidance GO:0007411 141 0.011
Fly
organelle transport along microtubule GO:0072384 14 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
regulation of secretion GO:0051046 274 0.011
establishment of synaptic vesicle localization GO:0097480 57 0.011
positive regulation of cell development GO:0010720 237 0.011
ear development GO:0043583 200 0.011
response to growth factor GO:0070848 198 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
positive regulation of cell cycle phase transition GO:1901989 17 0.010
mitotic chromosome condensation GO:0007076 1 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
muscle cell differentiation GO:0042692 261 0.010
Worm
regulation of innate immune response GO:0045088 91 0.010

Rdx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.225
Human
nervous system disease DOID:863 0 0.225
Human
sensory system disease DOID:0050155 0 0.205
Human
auditory system disease DOID:2742 0 0.068
Human
nonsyndromic deafness DOID:0050563 0 0.068
Human
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
retinal disease DOID:5679 0 0.014
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
central nervous system disease DOID:331 0 0.013
neurodegenerative disease DOID:1289 0 0.013
retinal degeneration DOID:8466 0 0.012