Mus musculus

13 known processes

Refbp2

RNA and export factor binding protein 2

(Aliases: C130042O11Rik,REF2,MGC117570)

Refbp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleic acid transport GO:0050657 18 0.682
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.385
Yeast
positive regulation of dna templated transcription elongation GO:0032786 2 0.385
poly a mrna export from nucleus GO:0016973 4 0.336
Mouse
mrna transport GO:0051028 13 0.280
regulation of dna recombination GO:0000018 34 0.269
establishment of rna localization GO:0051236 18 0.262
purine nucleotide catabolic process GO:0006195 211 0.245
Yeast
regulation of nucleoside metabolic process GO:0009118 130 0.219
Yeast
aromatic compound catabolic process GO:0019439 286 0.213
Yeast
regulation of nucleotide metabolic process GO:0006140 169 0.190
Yeast
nucleoside catabolic process GO:0009164 206 0.182
Yeast
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.174
nucleotide catabolic process GO:0009166 217 0.162
Yeast
cellular response to dna damage stimulus GO:0006974 207 0.161
Yeast
purine ribonucleoside catabolic process GO:0046130 205 0.150
Yeast
nitrogen compound transport GO:0071705 271 0.138
purine ribonucleoside metabolic process GO:0046128 241 0.130
Yeast
nucleoside triphosphate catabolic process GO:0009143 205 0.129
Yeast
negative regulation of molecular function GO:0044092 258 0.127
Yeast
purine nucleoside metabolic process GO:0042278 241 0.119
Yeast
regulation of hydrolase activity GO:0051336 246 0.114
Yeast
regulation of cellular catabolic process GO:0031329 242 0.112
Yeast
atp catabolic process GO:0006200 55 0.107
Yeast
nucleoside monophosphate catabolic process GO:0009125 59 0.104
Yeast
regulation of purine nucleotide catabolic process GO:0033121 122 0.101
Yeast
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.101
Yeast
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.097
Yeast
negative regulation of nucleotide catabolic process GO:0030812 9 0.097
Yeast
cellular nitrogen compound catabolic process GO:0044270 280 0.094
Yeast
dna repair GO:0006281 107 0.094
Yeast
negative regulation of nucleotide metabolic process GO:0045980 16 0.093
Yeast
rna transport GO:0050658 18 0.092
negative regulation of nucleoside metabolic process GO:0045978 11 0.091
Yeast
atp metabolic process GO:0046034 75 0.091
Yeast
microtubule cytoskeleton organization GO:0000226 157 0.090
negative regulation of dna templated transcription termination GO:0060567 1 0.090
negative regulation of atpase activity GO:0032780 2 0.088
Yeast
organophosphate catabolic process GO:0046434 232 0.088
Yeast
mitotic cell cycle process GO:1903047 159 0.086
purine ribonucleotide metabolic process GO:0009150 290 0.085
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 220 0.083
Yeast
myeloid cell differentiation GO:0030099 233 0.080
ribonucleoside catabolic process GO:0042454 206 0.079
Yeast
ribonucleotide metabolic process GO:0009259 291 0.079
Yeast
glycosyl compound catabolic process GO:1901658 206 0.075
Yeast
microtubule based process GO:0007017 236 0.072
purine nucleoside monophosphate catabolic process GO:0009128 58 0.071
Yeast
regulation of purine nucleotide metabolic process GO:1900542 169 0.070
Yeast
regulation of atp metabolic process GO:1903578 17 0.069
Yeast
purine containing compound metabolic process GO:0072521 311 0.069
Yeast
negative regulation of phosphate metabolic process GO:0045936 184 0.068
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 199 0.067
Yeast
ossification GO:0001503 216 0.067
regulation of nucleotide catabolic process GO:0030811 122 0.065
Yeast
nucleoside triphosphate metabolic process GO:0009141 230 0.064
Yeast
cellular amino acid metabolic process GO:0006520 103 0.064
regulation of cell cycle process GO:0010564 160 0.061
nucleocytoplasmic transport GO:0006913 139 0.061
Yeast Mouse
organic cyclic compound catabolic process GO:1901361 295 0.060
Yeast
nucleoside phosphate metabolic process GO:0006753 338 0.060
Yeast
nucleobase containing small molecule metabolic process GO:0055086 352 0.058
Yeast
guanosine containing compound metabolic process GO:1901068 144 0.056
regulation of mitotic cell cycle GO:0007346 126 0.056
rna processing GO:0006396 105 0.055
response to organonitrogen compound GO:0010243 246 0.054
negative regulation of cellular component organization GO:0051129 194 0.053
myosin filament assembly GO:0031034 2 0.052
cytoplasmic transport GO:0016482 234 0.051
Yeast Mouse
macromolecule catabolic process GO:0009057 281 0.050
nucleoside metabolic process GO:0009116 246 0.050
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.050
Yeast
mitotic cell cycle GO:0000278 195 0.049
spermatogenesis GO:0007283 284 0.048
regulation of cell division GO:0051302 76 0.048
regulation of mrna processing GO:0050684 41 0.048
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.047
apoptotic signaling pathway GO:0097190 306 0.047
carbohydrate metabolic process GO:0005975 230 0.047
organelle fission GO:0048285 170 0.045
nuclear transport GO:0051169 139 0.045
Yeast Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.045
Yeast
organonitrogen compound catabolic process GO:1901565 264 0.044
Yeast
dna recombination GO:0006310 92 0.044
purine nucleoside triphosphate metabolic process GO:0009144 226 0.043
Yeast
regulation of cell cycle GO:0051726 281 0.043
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.043
Yeast
cellular homeostasis GO:0019725 240 0.043
negative regulation of immune system process GO:0002683 209 0.042
purine nucleotide metabolic process GO:0006163 302 0.042
Yeast
oocyte construction GO:0007308 2 0.041
glycosyl compound metabolic process GO:1901657 246 0.041
Yeast
carbohydrate derivative catabolic process GO:1901136 231 0.041
Yeast
cell division GO:0051301 120 0.041
nucleobase containing compound transport GO:0015931 27 0.041
ribose phosphate metabolic process GO:0019693 291 0.040
Yeast
negative regulation of protein complex disassembly GO:0043242 22 0.038
endocytosis GO:0006897 168 0.038
purine nucleoside monophosphate metabolic process GO:0009126 81 0.038
Yeast
heterocycle catabolic process GO:0046700 280 0.038
Yeast
dna metabolic process GO:0006259 303 0.037
Yeast
mitotic nuclear division GO:0007067 48 0.037
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.036
regulation of organelle organization GO:0033043 289 0.035
ras protein signal transduction GO:0007265 77 0.035
male gamete generation GO:0048232 285 0.034
dna dependent dna replication GO:0006261 24 0.034
regulation of protein complex disassembly GO:0043244 28 0.033
nucleotide metabolic process GO:0009117 332 0.033
Yeast
dephosphorylation GO:0016311 129 0.032
oxidation reduction process GO:0055114 342 0.032
regulation of myeloid cell differentiation GO:0045637 96 0.032
transcription coupled nucleotide excision repair GO:0006283 2 0.032
Yeast
regulation of homeostatic process GO:0032844 182 0.032
rna splicing via transesterification reactions GO:0000375 43 0.032
response to organic cyclic compound GO:0014070 198 0.031
regulation of cellular component biogenesis GO:0044087 181 0.031
ribonucleoside monophosphate catabolic process GO:0009158 57 0.031
Yeast
muscle cell differentiation GO:0042692 261 0.031
positive regulation of cellular catabolic process GO:0031331 148 0.030
amine metabolic process GO:0009308 45 0.030
ribonucleoside metabolic process GO:0009119 245 0.030
Yeast
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.030
germ cell development GO:0007281 185 0.029
negative regulation of atp metabolic process GO:1903579 4 0.029
Yeast
cellular lipid metabolic process GO:0044255 323 0.028
purine nucleoside catabolic process GO:0006152 205 0.028
Yeast
regulation of dna damage checkpoint GO:2000001 3 0.027
protein alkylation GO:0008213 81 0.027
lymphocyte differentiation GO:0030098 242 0.027
cellular amine metabolic process GO:0044106 44 0.027
ribonucleotide catabolic process GO:0009261 208 0.027
Yeast
regionalization GO:0003002 337 0.026
meiotic nuclear division GO:0007126 115 0.026
rna localization GO:0006403 23 0.026
oocyte anterior posterior axis specification GO:0007314 2 0.026
cellular macromolecule catabolic process GO:0044265 206 0.026
positive regulation of cell death GO:0010942 224 0.026
response to acid chemical GO:0001101 111 0.025
regulation of glycogen catabolic process GO:0005981 2 0.025
glucose metabolic process GO:0006006 92 0.025
spermatid differentiation GO:0048515 115 0.025
sensory perception GO:0007600 245 0.025
negative regulation of phagocytosis GO:0050765 4 0.024
regulation of double strand break repair via homologous recombination GO:0010569 2 0.024
nuclear division GO:0000280 158 0.024
viral process GO:0016032 41 0.024
spermatid development GO:0007286 108 0.024
regulation of dna templated transcription termination GO:0031554 1 0.024
intracellular protein transport GO:0006886 204 0.024
cellular chemical homeostasis GO:0055082 215 0.023
regulation of cell projection organization GO:0031344 206 0.023
dna templated transcription elongation GO:0006354 13 0.023
regulation of cellular ketone metabolic process GO:0010565 66 0.023
lipid biosynthetic process GO:0008610 179 0.023
regulation of cellular response to stress GO:0080135 159 0.023
oocyte axis specification GO:0007309 2 0.022
positive regulation of mitotic cell cycle GO:0045931 41 0.022
cellular response to glucose stimulus GO:0071333 45 0.022
dna templated transcription termination GO:0006353 4 0.022
multicellular organism growth GO:0035264 161 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
regulation of cellular amino acid metabolic process GO:0006521 5 0.022
negative regulation of cell projection organization GO:0031345 56 0.022
regulation of mrna splicing via spliceosome GO:0048024 32 0.022
development of primary sexual characteristics GO:0045137 143 0.021
small molecule biosynthetic process GO:0044283 132 0.021
myosin filament organization GO:0031033 3 0.021
regulation of cell cycle phase transition GO:1901987 77 0.021
intracellular transport of virus GO:0075733 1 0.021
organelle localization GO:0051640 179 0.021
monosaccharide metabolic process GO:0005996 106 0.021
inflammatory response GO:0006954 244 0.021
regulation of mrna metabolic process GO:1903311 43 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
Yeast
regulation of translation GO:0006417 71 0.021
negative regulation of hydrolase activity GO:0051346 71 0.020
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
translation GO:0006412 93 0.020
regulation of carbohydrate metabolic process GO:0006109 75 0.020
compound eye development GO:0048749 1 0.020
cellular protein complex assembly GO:0043623 116 0.020
hexose metabolic process GO:0019318 98 0.020
cation transport GO:0006812 399 0.020
regulation of dna templated transcription elongation GO:0032784 10 0.020
cation transmembrane transport GO:0098655 266 0.020
regulation of cell motility GO:2000145 236 0.019
interspecies interaction between organisms GO:0044419 83 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
mrna splicing via spliceosome GO:0000398 43 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
leukocyte differentiation GO:0002521 342 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
dna replication GO:0006260 52 0.019
cellular response to hexose stimulus GO:0071331 47 0.019
cellular response to lipid GO:0071396 145 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
Yeast
regulation of apoptotic signaling pathway GO:2001233 197 0.019
chromatin organization GO:0006325 206 0.018
nuclear export GO:0051168 34 0.018
Yeast Mouse
striated muscle myosin thick filament assembly GO:0071688 1 0.018
response to lipopolysaccharide GO:0032496 128 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.017
striated muscle tissue development GO:0014706 293 0.017
cell type specific apoptotic process GO:0097285 268 0.017
negative regulation of cell cycle GO:0045786 123 0.017
establishment of organelle localization GO:0051656 122 0.017
positive regulation of protein modification process GO:0031401 299 0.017
glucose homeostasis GO:0042593 128 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
skeletal system development GO:0001501 356 0.017
b cell activation GO:0042113 161 0.017
negative regulation of apoptotic cell clearance GO:2000426 1 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.016
macromolecule methylation GO:0043414 120 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
nucleotide excision repair GO:0006289 13 0.016
Yeast
carbohydrate homeostasis GO:0033500 128 0.016
positive regulation of cell development GO:0010720 237 0.016
rna export from nucleus GO:0006405 15 0.016
Yeast Mouse
viral life cycle GO:0019058 36 0.016
response to starvation GO:0042594 65 0.016
regulation of gtp catabolic process GO:0033124 113 0.016
peptidyl amino acid modification GO:0018193 336 0.016
regulation of transferase activity GO:0051338 263 0.016
synaptic transmission GO:0007268 329 0.016
muscle tissue development GO:0060537 308 0.016
intracellular mrna localization GO:0008298 4 0.015
actin cytoskeleton organization GO:0030036 220 0.015
respiratory system development GO:0060541 190 0.015
response to nutrient levels GO:0031667 109 0.015
multi multicellular organism process GO:0044706 109 0.015
purine containing compound catabolic process GO:0072523 213 0.015
Yeast
lung development GO:0030324 164 0.015
histone modification GO:0016570 159 0.015
cardiac muscle contraction GO:0060048 32 0.015
peptidyl arginine omega n methylation GO:0035247 2 0.015
regulation of multi organism process GO:0043900 111 0.015
nucleoside phosphate biosynthetic process GO:1901293 79 0.015
cellular response to monosaccharide stimulus GO:0071326 47 0.015
regulation of cell migration GO:0030334 219 0.014
regulation of glucose metabolic process GO:0010906 60 0.014
protein ubiquitination GO:0016567 171 0.014
respiratory tube development GO:0030323 167 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
cellular protein catabolic process GO:0044257 155 0.014
protein localization to organelle GO:0033365 185 0.014
positive regulation of cell cycle GO:0045787 92 0.014
negative regulation of myeloid cell differentiation GO:0045638 38 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
muscle cell development GO:0055001 133 0.014
mrna export from nucleus GO:0006406 11 0.014
Yeast Mouse
cell adhesion GO:0007155 329 0.014
cellular ketone metabolic process GO:0042180 84 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
energy derivation by oxidation of organic compounds GO:0015980 77 0.013
spindle organization GO:0007051 28 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
macromolecular complex disassembly GO:0032984 43 0.013
response to extracellular stimulus GO:0009991 127 0.013
regulation of secretion GO:0051046 274 0.013
gtp metabolic process GO:0046039 144 0.013
adult locomotory behavior GO:0008344 91 0.013
maintenance of location GO:0051235 89 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
rna splicing GO:0008380 54 0.013
homeostasis of number of cells GO:0048872 210 0.013
ion transmembrane transport GO:0034220 361 0.013
organism emergence from protective structure GO:0071684 4 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
regulation of defense response GO:0031347 233 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
regulation of proteolysis GO:0030162 164 0.012
cellularization GO:0007349 1 0.012
regulation of membrane potential GO:0042391 192 0.012
digestive system development GO:0055123 200 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
cell cycle checkpoint GO:0000075 47 0.012
circulatory system process GO:0003013 197 0.012
blood circulation GO:0008015 195 0.012
chromatin modification GO:0016568 187 0.012
positive regulation of cell cycle process GO:0090068 61 0.012
blastocyst development GO:0001824 80 0.012
meiotic cell cycle GO:0051321 122 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
cellular response to carbohydrate stimulus GO:0071322 50 0.012
membrane organization GO:0061024 245 0.012
protein maturation GO:0051604 176 0.012
negative regulation of translation GO:0017148 22 0.011
regulation of secretion by cell GO:1903530 249 0.011
mitochondrion organization GO:0007005 134 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
locomotory behavior GO:0007626 195 0.011
lipid localization GO:0010876 126 0.011
extracellular matrix organization GO:0030198 147 0.011
positive regulation of cytoskeleton organization GO:0051495 49 0.011
mrna processing GO:0006397 63 0.011
glycerolipid metabolic process GO:0046486 122 0.011
protein complex disassembly GO:0043241 40 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
positive regulation of cellular amine metabolic process GO:0033240 5 0.011
oogenesis GO:0048477 56 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
endomembrane system organization GO:0010256 147 0.011
regulation of meiotic cell cycle GO:0051445 34 0.011
striated muscle contraction GO:0006941 45 0.011
male sex differentiation GO:0046661 109 0.011
negative regulation of response to wounding GO:1903035 77 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
positive regulation of nuclear division GO:0051785 27 0.011
connective tissue development GO:0061448 179 0.011
regulation of rna splicing GO:0043484 37 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
Yeast
positive regulation of apoptotic process GO:0043065 217 0.011
response to steroid hormone GO:0048545 56 0.011
positive regulation of cell division GO:0051781 31 0.011
phospholipid metabolic process GO:0006644 87 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.010
generation of precursor metabolites and energy GO:0006091 103 0.010
heart contraction GO:0060047 93 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
covalent chromatin modification GO:0016569 163 0.010
fertilization GO:0009566 127 0.010
regulation of protein localization GO:0032880 231 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
energy reserve metabolic process GO:0006112 39 0.010
regulation of neuron differentiation GO:0045664 281 0.010
negative regulation of response to dna damage stimulus GO:2001021 10 0.010
epithelial tube morphogenesis GO:0060562 303 0.010

Refbp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
nervous system disease DOID:863 0 0.050
central nervous system disease DOID:331 0 0.040
neurodegenerative disease DOID:1289 0 0.015