|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.819
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.814
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.807
|
Mouse |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.802
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.762
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.757
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.738
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.729
|
Mouse |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.706
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.692
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.680
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.656
|
Mouse |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.653
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.649
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.630
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.620
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.601
|
Mouse |
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.568
|
Mouse |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.561
|
Mouse |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.534
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.513
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.502
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.490
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.488
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.483
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.481
|
Mouse |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.469
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
111 |
0.443
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.416
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.415
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.415
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.405
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.396
|
Mouse |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.395
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.394
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.371
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.369
|
Mouse |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.365
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.362
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.362
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.359
|
Mouse |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.351
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.347
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.347
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.344
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.343
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.343
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.342
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.331
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.331
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.324
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.317
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.315
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.314
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.313
|
Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.309
|
Mouse |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.301
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.290
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.286
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.286
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.283
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.282
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.279
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.277
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.271
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.269
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.266
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.265
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.264
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.262
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.255
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.253
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.252
|
Mouse |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.250
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.238
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.236
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.236
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.231
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.229
|
Mouse |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.227
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.226
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.222
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.220
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.216
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.216
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.215
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.212
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.209
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.209
|
Mouse |
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.205
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.204
|
Mouse |
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.203
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.203
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.201
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.200
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.196
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.195
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.194
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.193
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.192
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.192
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.187
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.187
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.178
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.176
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.176
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.174
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.173
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.170
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.170
|
Mouse |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.166
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.165
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.164
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.162
|
Mouse |
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.162
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.162
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.161
|
|
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.158
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.157
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.157
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.155
|
Mouse |
|
|
regulation of interleukin 4 biosynthetic process
|
GO:0045402 |
3 |
0.155
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.153
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.151
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.151
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.149
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.149
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.149
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.148
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.146
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.146
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.145
|
Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.145
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.143
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.143
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.142
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.141
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.141
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.141
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.140
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.138
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.138
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.137
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.137
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.137
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.136
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.135
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.133
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.132
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.131
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.130
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.130
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.129
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.126
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.126
|
Mouse |
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.123
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.123
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.123
|
Mouse |
|
|
chemokine production
|
GO:0032602 |
34 |
0.121
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.121
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.120
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.119
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.119
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.119
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.118
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.118
|
Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.117
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.116
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.116
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.115
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.115
|
Human Mouse |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.115
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.114
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.114
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.113
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.112
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.112
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.109
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.109
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.108
|
Mouse |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.108
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.107
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.106
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.106
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.105
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.105
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.104
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.104
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.103
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.103
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.102
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.102
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.101
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.100
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.099
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.097
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.096
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.096
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.096
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.095
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.095
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.094
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.094
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.093
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.093
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.092
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.092
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.092
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.092
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.091
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.091
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.090
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.090
|
Mouse |
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.089
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.089
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.089
|
Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.088
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.087
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.086
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.086
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.085
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.085
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.085
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.085
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.084
|
Mouse |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.084
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.084
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.083
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.082
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.082
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.082
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.081
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.081
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.081
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.081
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.080
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.080
|
Mouse |
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.079
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.079
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.078
|
|
|
|
negative regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031665 |
3 |
0.078
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.078
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.076
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.076
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.076
|
Mouse |
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.075
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.075
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.075
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.075
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.074
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.074
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.074
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.074
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.074
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.074
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.072
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.072
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.071
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.070
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.070
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.068
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.068
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.068
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.068
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.067
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.067
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.066
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.066
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.066
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.066
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.065
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.065
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.065
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.065
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.064
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.064
|
Mouse |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.063
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.063
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.063
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.063
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.062
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.062
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.062
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.062
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.061
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.061
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.061
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.061
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.061
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.060
|
Mouse |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.060
|
Mouse |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.060
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.059
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.059
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.059
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.058
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.058
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.057
|
Mouse |
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.057
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.057
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.057
|
Mouse |
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.057
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.057
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.056
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.056
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.056
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.056
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.056
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.056
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.056
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.056
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.055
|
Mouse |
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.054
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.054
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.054
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.054
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.053
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.053
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.053
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.053
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.053
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.053
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.053
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.053
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.053
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.053
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.052
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.052
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.052
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.052
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.052
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.052
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.051
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.051
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.051
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.051
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.051
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.050
|
Mouse |
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.050
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.050
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.050
|
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
35 |
0.049
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.049
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.049
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.049
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.049
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.049
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.049
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.049
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.049
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.048
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.048
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.048
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.048
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.048
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.048
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.047
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.047
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.047
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.046
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.046
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.046
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.046
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.046
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.046
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.046
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.045
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.045
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.045
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.045
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.045
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.045
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.045
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.045
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.044
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.044
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.044
|
|
|
|
natural killer cell proliferation
|
GO:0001787 |
3 |
0.044
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.044
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.044
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.044
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.044
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.044
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.044
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.044
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.043
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.043
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.043
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.043
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.043
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.043
|
|
|
|
regulation of action potential
|
GO:0098900 |
4 |
0.043
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.043
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.043
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.043
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.043
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.043
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.043
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.043
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.042
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.042
|
Mouse |
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.042
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.042
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.042
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.042
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.041
|
Mouse |
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.041
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
26 |
0.041
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.041
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.041
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.041
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.041
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.041
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.041
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.040
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.040
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.040
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.040
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.040
|
|
|
|
type i interferon production
|
GO:0032606 |
29 |
0.040
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.040
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.040
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.040
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.040
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.040
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.040
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.040
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.039
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
20 |
0.039
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.039
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.039
|
|
|
|
translation
|
GO:0006412 |
93 |
0.039
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.039
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.039
|
|
|
|
interleukin 33 mediated signaling pathway
|
GO:0038172 |
1 |
0.039
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.039
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.039
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.039
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.039
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.039
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.039
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.038
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.038
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.038
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.038
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.038
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.038
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.038
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.038
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.037
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.037
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.037
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.037
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.037
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.037
|
|
|
|
epithalamus development
|
GO:0021538 |
2 |
0.037
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.037
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.037
|
Mouse |
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.037
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.037
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.037
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.036
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.036
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.036
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.036
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.036
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.036
|
|
|
|
negative regulation of chemokine production
|
GO:0032682 |
4 |
0.036
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.036
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.036
|
|
|
|
positive regulation of macrophage activation
|
GO:0043032 |
10 |
0.036
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.036
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.036
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.036
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.036
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.035
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.035
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.035
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.035
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.035
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.035
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.035
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.035
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.035
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.035
|
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.035
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.035
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.035
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.035
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
14 |
0.034
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.034
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.034
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.034
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.034
|
|
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
9 |
0.034
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.034
|
|
