|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
1.000
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
1.000
|
|
|
|
germinal center formation
|
GO:0002467 |
16 |
1.000
|
Mouse |
|
|
marginal zone b cell differentiation
|
GO:0002315 |
2 |
1.000
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
1.000
|
Mouse |
|
|
follicular dendritic cell differentiation
|
GO:0002268 |
2 |
1.000
|
Mouse |
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
1.000
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.999
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.998
|
Mouse |
|
|
regulation of defense response to fungus
|
GO:1900150 |
1 |
0.998
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.998
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.997
|
Human |
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.997
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.997
|
Human |
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.996
|
|
|
|
negative regulation of tumor necrosis factor biosynthetic process
|
GO:0042536 |
1 |
0.996
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.996
|
Mouse |
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.995
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.994
|
Mouse |
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.993
|
Mouse |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.993
|
Mouse |
|
|
nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070427 |
5 |
0.990
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.989
|
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.989
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.987
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.986
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.985
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.985
|
Human |
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.983
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.981
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.980
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.980
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.980
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.978
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.978
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.976
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.973
|
Human |
|
|
follicular dendritic cell activation
|
GO:0002266 |
2 |
0.972
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.972
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.972
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.970
|
Human |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.968
|
Mouse |
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.967
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.964
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.961
|
Mouse |
|
|
defense response to fungus
|
GO:0050832 |
12 |
0.961
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.960
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.960
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
319 |
0.959
|
|
|
|
protein import into nucleus translocation
|
GO:0000060 |
12 |
0.958
|
|
|
|
peptide biosynthetic process
|
GO:0043043 |
11 |
0.957
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.954
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.954
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.952
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.949
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.949
|
Mouse |
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.946
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.945
|
|
|
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
13 |
0.936
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.934
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.931
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.931
|
Human |
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.927
|
|
|
|
regulation of interleukin 10 biosynthetic process
|
GO:0045074 |
1 |
0.923
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.922
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.914
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.913
|
Mouse |
|
|
humoral immune response
|
GO:0006959 |
57 |
0.912
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.904
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.904
|
Human |
|
|
positive regulation of interleukin 10 biosynthetic process
|
GO:0045082 |
1 |
0.903
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.902
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.901
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.900
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.891
|
Human |
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.885
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.884
|
Human |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.883
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.880
|
Human |
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.880
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.874
|
|
|
|
interleukin 10 biosynthetic process
|
GO:0042091 |
1 |
0.867
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.864
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.862
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.860
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.856
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
10 |
0.854
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.853
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.852
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.851
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.849
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.839
|
Mouse |
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.830
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.828
|
Mouse |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.826
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.824
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.823
|
Human |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.818
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.816
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.814
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.811
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.810
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.806
|
Mouse |
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.805
|
Mouse |
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.784
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.782
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.778
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.778
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.777
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.776
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.771
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.769
|
Mouse |
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
6 |
0.758
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.756
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.751
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.747
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.735
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.726
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.719
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.716
|
Human |
|
|
histone modification
|
GO:0016570 |
159 |
0.716
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.710
|
Mouse |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.707
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.699
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.697
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.697
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.697
|
|
|
|
response to interleukin 6
|
GO:0070741 |
10 |
0.692
|
Human |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.691
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.682
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.679
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.675
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.671
|
Mouse |
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.669
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.667
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.662
|
Human |
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.660
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.658
|
Mouse |
|
|
liver development
|
GO:0001889 |
66 |
0.652
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.642
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.634
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
21 |
0.627
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.623
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.619
|
|
|
|
negative regulation of interleukin 12 biosynthetic process
|
GO:0045083 |
1 |
0.618
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.616
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.615
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.609
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.607
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.602
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.599
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.595
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.589
|
|
|
|
interleukin 12 biosynthetic process
|
GO:0042090 |
8 |
0.589
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.588
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.588
|
Zebrafish |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.587
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.582
|
Human |
|
|
cytoplasmic sequestering of transcription factor
|
GO:0042994 |
5 |
0.581
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.580
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.569
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.568
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.561
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.560
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.560
|
Mouse |
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.556
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.554
|
Human |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.544
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.543
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.539
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.537
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.535
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.534
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.533
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.530
|
Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.526
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.526
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
29 |
0.520
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.516
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.516
|
Mouse |
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.514
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
24 |
0.513
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.513
|
Mouse |
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.509
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.499
|
|
|
|
positive regulation of cholesterol efflux
|
GO:0010875 |
9 |
0.488
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.483
|
|
|
|
response to dsrna
|
GO:0043331 |
30 |
0.483
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.480
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.476
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.475
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.472
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.471
|
Mouse |
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.470
|
|
|
|
regulation of cellular amide metabolic process
|
GO:0034248 |
10 |
0.470
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.465
|
|
|
|
natural killer cell proliferation
|
GO:0001787 |
3 |
0.455
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.455
|
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
9 |
0.454
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.450
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
20 |
0.448
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
11 |
0.444
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.441
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.428
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.427
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.426
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.413
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.410
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.398
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.398
|
|
|
|
response to type i interferon
|
GO:0034340 |
12 |
0.397
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
9 |
0.396
|
Human |
|
|
regulation of interleukin 12 biosynthetic process
|
GO:0045075 |
8 |
0.390
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.389
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.385
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.382
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.378
|
Human |
|
|
regulation of vitamin metabolic process
|
GO:0030656 |
3 |
0.377
|
|
|
|
hyaluronan biosynthetic process
|
GO:0030213 |
3 |
0.377
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.376
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.374
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.371
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.370
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.367
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.359
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.357
|
Mouse |
|
|
positive regulation of response to biotic stimulus
|
GO:0002833 |
15 |
0.347
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.344
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.339
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.338
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.337
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.336
|
|
|
|
positive regulation of antibacterial peptide production
|
GO:0002803 |
1 |
0.331
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.326
|
Mouse |
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.326
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.325
|
Human |
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
40 |
0.325
|
|
|
|
mature b cell differentiation involved in immune response
|
GO:0002313 |
9 |
0.325
|
|
|
|
regulation of vitamin d biosynthetic process
|
GO:0060556 |
1 |
0.325
|
|
|
|
amide biosynthetic process
|
GO:0043604 |
16 |
0.324
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.322
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.320
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.319
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.316
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
38 |
0.313
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.312
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
5 |
0.312
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.311
|
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.308
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.305
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
54 |
0.300
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.300
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
2 |
0.299
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
23 |
0.295
|
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
5 |
0.294
|
|
|
|
regulation of lipid storage
|
GO:0010883 |
20 |
0.294
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.291
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.290
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.289
|
Mouse |
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.288
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.287
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.284
|
Mouse |
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
7 |
0.284
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.284
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.283
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.280
|
|
|
|
negative regulation of tumor necrosis factor production
|
GO:0032720 |
17 |
0.272
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.270
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.269
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.268
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.267
|
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
2 |
0.264
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.263
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.258
|
|
|
|
interleukin 10 production
|
GO:0032613 |
23 |
0.257
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.255
|
Human |
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.254
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.254
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.253
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.248
|
Mouse |
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.247
|
Mouse |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.247
|
|
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.246
|
|
|
|
regulation of lamellipodium assembly
|
GO:0010591 |
3 |
0.244
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.241
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.241
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.240
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.238
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.233
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.233
|
|
|
|
myd88 dependent toll like receptor signaling pathway
|
GO:0002755 |
7 |
0.227
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.226
|
|
|
|
negative regulation of transcription factor import into nucleus
|
GO:0042992 |
13 |
0.225
|
|
|
|
type i interferon production
|
GO:0032606 |
29 |
0.223
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.223
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.222
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.221
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.215
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.215
|
|
|
|
progesterone metabolic process
|
GO:0042448 |
4 |
0.214
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.213
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.212
|
Human |
|
|
response to peptide
|
GO:1901652 |
136 |
0.210
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.209
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.205
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.204
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.203
|
Mouse |
|
|
negative regulation of platelet derived growth factor receptor beta signaling pathway
|
GO:2000587 |
2 |
0.203
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.202
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.201
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.201
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.200
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.199
|
Mouse |
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.198
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.197
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.195
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.195
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.191
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.189
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.188
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.187
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.185
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.185
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.183
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.179
|
Human |
|
|
transformed cell apoptotic process
|
GO:0006927 |
3 |
0.179
|
|
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
2 |
0.178
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.177
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.176
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.176
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.175
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.174
|
|
|
|
positive regulation of mast cell differentiation
|
GO:0060376 |
1 |
0.173
|
|
|
|
positive regulation of cellular amide metabolic process
|
GO:0034250 |
5 |
0.173
|
|
|
|
positive regulation of growth hormone receptor signaling pathway
|
GO:0060399 |
3 |
0.172
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.172
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.171
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
11 |
0.171
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.168
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
63 |
0.167
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.165
|
|
|
|
aminoglycan metabolic process
|
GO:0006022 |
34 |
0.163
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.159
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.158
|
|
|
|
positive regulation of cholesterol transport
|
GO:0032376 |
9 |
0.157
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.156
|
|
|
|
isoleucine metabolic process
|
GO:0006549 |
4 |
0.156
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.154
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.154
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.152
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.151
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.151
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.150
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.150
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.150
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.147
|
|
|
|
response to exogenous dsrna
|
GO:0043330 |
22 |
0.146
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.146
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.145
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
30 |
0.145
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.144
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.144
|
Zebrafish |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.144
|
|
|
|
regulation of dna binding
|
GO:0051101 |
39 |
0.143
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.143
|
|
|
|
negative regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042524 |
2 |
0.143
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.142
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.142
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.142
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.141
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.140
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.140
|
|
|
|
regulation of interleukin 13 secretion
|
GO:2000665 |
2 |
0.139
|
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.137
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.137
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.135
|
|
|
|
t helper 1 cell lineage commitment
|
GO:0002296 |
2 |
0.134
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.131
|
Mouse |
|
|
amide transport
|
GO:0042886 |
138 |
0.131
|
|
|
|
negative regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903556 |
17 |
0.131
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.130
|
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
18 |
0.129
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.129
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.128
|
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
3 |
0.128
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.127
|
|
|
|
cholesterol efflux
|
GO:0033344 |
24 |
0.127
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.127
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.127
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.126
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.125
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.124
|
|
|
|
positive regulation of interleukin 10 production
|
GO:0032733 |
12 |
0.124
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.124
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.123
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.123
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.122
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.122
|
|
|
|
positive regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042511 |
1 |
0.121
|
|
|
|
negative regulation of interferon gamma mediated signaling pathway
|
GO:0060336 |
1 |
0.120
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.119
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.118
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.118
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.118
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.118
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.117
|
|
|
|
interleukin 13 secretion
|
GO:0072611 |
2 |
0.117
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.117
|
|
|
|
positive regulation of natural killer cell activation
|
GO:0032816 |
15 |
0.116
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.115
|
Mouse |
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.113
|
|
|
|
negative regulation of t helper 1 cell differentiation
|
GO:0045626 |
3 |
0.113
|
|
|
|
macrophage fusion
|
GO:0034238 |
3 |
0.112
|
|
|
|
prolactin signaling pathway
|
GO:0038161 |
5 |
0.111
|
|
|
|
negative regulation of interleukin 12 production
|
GO:0032695 |
10 |
0.110
|
Mouse |
|
|
positive regulation of sterol transport
|
GO:0032373 |
9 |
0.109
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.109
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.109
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.108
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.108
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.107
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.106
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.106
|
|
|
|
protein deacylation
|
GO:0035601 |
36 |
0.106
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.106
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.106
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
0.105
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.105
|
|
|
|
mature b cell differentiation
|
GO:0002335 |
13 |
0.105
|
|
|
|
inner ear receptor cell development
|
GO:0060119 |
39 |
0.103
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.103
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.103
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.100
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.100
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
26 |
0.099
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.099
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.098
|
|
|
|
transforming growth factor beta2 production
|
GO:0032906 |
2 |
0.097
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.096
|
Mouse |
|
|
nuclear transcribed mrna catabolic process deadenylation dependent decay
|
GO:0000288 |
12 |
0.096
|
|
|
|
protein complex localization
|
GO:0031503 |
19 |
0.096
|
|
|
|
dna modification
|
GO:0006304 |
50 |
0.095
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.095
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.094
|
|
|
|
positive regulation of mirna metabolic process
|
GO:2000630 |
1 |
0.093
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.093
|
|
|
|
regulation of polysaccharide metabolic process
|
GO:0032881 |
13 |
0.092
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.092
|
Human |
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.092
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.091
|
|
|
|
somatic stem cell division
|
GO:0048103 |
19 |
0.091
|
|
|
|
regulation of interleukin 5 secretion
|
GO:2000662 |
2 |
0.091
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.090
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
28 |
0.090
|
|
|
|
positive regulation of receptor biosynthetic process
|
GO:0010870 |
1 |
0.089
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.089
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.089
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.088
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.087
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.087
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.086
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.085
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.085
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.085
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.085
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.085
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.084
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.084
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.084
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.084
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.084
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.084
|
|
|
|
development of secondary male sexual characteristics
|
GO:0046544 |
3 |
0.084
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.083
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.083
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.083
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.082
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.082
|
|
|
|
negative regulation of fat cell differentiation
|
GO:0045599 |
36 |
0.081
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.081
|
|
|
|
creatinine metabolic process
|
GO:0046449 |
3 |
0.081
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.080
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.080
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.080
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.080
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.080
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.080
|
|
|
|
hyaluronan metabolic process
|
GO:0030212 |
4 |
0.079
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.079
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.079
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.078
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
34 |
0.078
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
14 |
0.078
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.078
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.077
|
|
|
|
negative regulation of interleukin 8 production
|
GO:0032717 |
1 |
0.077
|
|
|
|
positive regulation of isotype switching to ige isotypes
|
GO:0048295 |
4 |
0.077
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.077
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.076
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
2 |
0.076
|
|
