|
|
marginal zone b cell differentiation
|
GO:0002315 |
2 |
1.000
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
1.000
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
1.000
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
1.000
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
1.000
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
1.000
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
1.000
|
|
|
|
negative regulation of tumor necrosis factor biosynthetic process
|
GO:0042536 |
1 |
1.000
|
|
|
|
follicular dendritic cell differentiation
|
GO:0002268 |
2 |
1.000
|
Mouse |
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
6 |
1.000
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.999
|
|
|
|
nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070427 |
5 |
0.999
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.999
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.999
|
|
|
|
regulation of defense response to fungus
|
GO:1900150 |
1 |
0.999
|
|
|
|
interleukin 12 biosynthetic process
|
GO:0042090 |
8 |
0.999
|
Mouse |
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.998
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.998
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.998
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.998
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.997
|
|
|
|
follicular dendritic cell activation
|
GO:0002266 |
2 |
0.997
|
Mouse |
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.997
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.996
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.996
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.996
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.996
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.996
|
|
|
|
germinal center formation
|
GO:0002467 |
16 |
0.996
|
Mouse |
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.995
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.994
|
Mouse |
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.994
|
|
|
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
13 |
0.992
|
Mouse |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.992
|
|
|
|
defense response to fungus
|
GO:0050832 |
12 |
0.992
|
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.992
|
|
|
|
regulation of interleukin 10 biosynthetic process
|
GO:0045074 |
1 |
0.992
|
|
|
|
peptide biosynthetic process
|
GO:0043043 |
11 |
0.991
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.991
|
Mouse |
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.990
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.989
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.988
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.987
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.987
|
|
|
|
positive regulation of interleukin 10 biosynthetic process
|
GO:0045082 |
1 |
0.985
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.985
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.985
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.984
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.982
|
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
9 |
0.982
|
Mouse |
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.982
|
|
|
|
interleukin 10 biosynthetic process
|
GO:0042091 |
1 |
0.981
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.980
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.979
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.979
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.978
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.978
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.978
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.977
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.977
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.977
|
Mouse |
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.973
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.973
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.972
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.972
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.972
|
|
|
|
protein import into nucleus translocation
|
GO:0000060 |
12 |
0.966
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.966
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.964
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.964
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.963
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.962
|
Mouse |
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.957
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.954
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.951
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.950
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.947
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.947
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.947
|
Mouse |
|
|
spleen development
|
GO:0048536 |
39 |
0.945
|
Mouse |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.943
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.943
|
Mouse |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.941
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.937
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.931
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.929
|
Mouse |
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.925
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.925
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.918
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.918
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.915
|
Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.912
|
Mouse |
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.908
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.907
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.906
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.901
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.897
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.892
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.886
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.886
|
|
|
|
negative regulation of t helper 1 cell differentiation
|
GO:0045626 |
3 |
0.885
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.876
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.876
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.876
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.875
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.872
|
|
|
|
vitamin d biosynthetic process
|
GO:0042368 |
3 |
0.868
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.867
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.865
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.862
|
Mouse |
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
6 |
0.862
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.861
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.857
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.857
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.855
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.852
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.840
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.836
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.836
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.833
|
Mouse |
|
|
t cell activation
|
GO:0042110 |
289 |
0.822
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.816
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.809
|
|
|
|
response to dsrna
|
GO:0043331 |
30 |
0.804
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.803
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.800
|
Mouse |
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.800
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.799
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.796
|
Mouse |
|
|
regulation of vitamin d biosynthetic process
|
GO:0060556 |
1 |
0.793
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.790
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.781
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.778
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.773
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.769
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.764
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.763
|
|
|
|
positive regulation of mirna metabolic process
|
GO:2000630 |
1 |
0.757
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.757
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.753
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.750
|
Mouse |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.749
|
|
|
|
regulation of interleukin 12 biosynthetic process
|
GO:0045075 |
8 |
0.749
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.742
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.737
|
Mouse |
|
|
nucleotide binding domain leucine rich repeat containing receptor signaling pathway
|
GO:0035872 |
6 |
0.729
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.723
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.722
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.720
|
Mouse |
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.720
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
25 |
0.717
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.717
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.715
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.714
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.713
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.710
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.703
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.702
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.700
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.690
|
Mouse |
|
|
positive regulation of interleukin 10 production
|
GO:0032733 |
12 |
0.689
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.688
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.683
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.682
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.679
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.676
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.674
|
Mouse |
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.667
|
|
|
|
regulation of cellular amide metabolic process
|
GO:0034248 |
10 |
0.663
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.657
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.650
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.640
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.640
|
Mouse |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.639
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.636
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.633
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.629
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.628
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.613
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.611
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.609
|
|
|
|
interleukin 10 production
|
GO:0032613 |
23 |
0.606
|
|
|
|
positive regulation of interleukin 12 biosynthetic process
|
GO:0045084 |
6 |
0.602
|
Mouse |
|
|
regulation of polysaccharide metabolic process
|
GO:0032881 |
13 |
0.601
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.599
|
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.596
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.592
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.591
|
Mouse |
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.588
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.584
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.576
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.575
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.573
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.573
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.572
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.572
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.569
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.569
|
|
|
|
fat soluble vitamin biosynthetic process
|
GO:0042362 |
4 |
0.564
|
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
18 |
0.564
|
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.551
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.546
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.546
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.544
|
Mouse |
|
|
regulation of vitamin metabolic process
|
GO:0030656 |
3 |
0.539
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.539
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.526
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.520
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.517
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.516
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.508
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.504
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.491
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.489
|
Mouse |
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.482
|
|
|
|
negative regulation of tumor necrosis factor production
|
GO:0032720 |
17 |
0.481
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.480
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.479
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.477
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.476
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.472
|
Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.468
|
|
|
|
hyaluronan biosynthetic process
|
GO:0030213 |
3 |
0.466
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.466
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.453
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.452
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.451
|
|
|
|
negative regulation of monooxygenase activity
|
GO:0032769 |
3 |
0.445
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.445
|
Mouse |
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.444
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.444
|
Mouse |
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.436
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.435
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.434
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.428
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.428
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.426
|
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.426
|
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
3 |
0.423
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.422
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.422
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.418
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.412
|
Mouse |
|
|
positive regulation of response to biotic stimulus
|
GO:0002833 |
15 |
0.409
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.404
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.402
|
|
|
|
negative regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903556 |
17 |
0.396
|
|
|
|
positive regulation of antibacterial peptide production
|
GO:0002803 |
1 |
0.393
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.393
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.389
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.388
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.388
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.385
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.383
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.382
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.380
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
2 |
0.379
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.377
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.374
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.374
|
|
|
|
mirna metabolic process
|
GO:0010586 |
10 |
0.374
|
|
|
|
interleukin 13 secretion
|
GO:0072611 |
2 |
0.371
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.366
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.364
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.362
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.361
|
|
|
|
negative regulation of alpha beta t cell differentiation
|
GO:0046639 |
12 |
0.357
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.356
|
|
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.351
|
|
|
|
regulation of mirna metabolic process
|
GO:2000628 |
4 |
0.349
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.349
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.349
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.345
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.340
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.336
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.336
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.336
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
36 |
0.336
|
Mouse |
|
|
nuclear import
|
GO:0051170 |
95 |
0.335
|
|
|
|
regulation of t helper 2 cell differentiation
|
GO:0045628 |
8 |
0.335
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.334
|
Mouse |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.333
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.328
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.318
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.311
|
|
|
|
myd88 dependent toll like receptor signaling pathway
|
GO:0002755 |
7 |
0.309
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.306
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.305
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.304
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.304
|
|
|
|
aminoglycan metabolic process
|
GO:0006022 |
34 |
0.301
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.300
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.298
|
|
|
|
negative regulation of cd4 positive alpha beta t cell activation
|
GO:2000515 |
10 |
0.298
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.296
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.292
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.291
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.291
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.289
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
40 |
0.289
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.288
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.284
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.284
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.283
|
|
|
|
fat soluble vitamin metabolic process
|
GO:0006775 |
11 |
0.283
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.283
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.278
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.278
|
|
|
|
mature b cell differentiation
|
GO:0002335 |
13 |
0.277
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.275
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.272
|
|
|
|
mature b cell differentiation involved in immune response
|
GO:0002313 |
9 |
0.271
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.269
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.268
|
|
|
|
response to nicotine
|
GO:0035094 |
6 |
0.265
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.265
|
|
|
|
positive regulation of macrophage activation
|
GO:0043032 |
10 |
0.264
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.264
|
Mouse |
|
|
temperature homeostasis
|
GO:0001659 |
26 |
0.264
|
|
|
|
positive regulation of cholesterol transport
|
GO:0032376 |
9 |
0.263
|
|
|
|
negative regulation of oxidoreductase activity
|
GO:0051354 |
4 |
0.261
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.261
|
|
|
|
negative regulation of t helper cell differentiation
|
GO:0045623 |
9 |
0.260
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.260
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.258
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.257
|
|
|
|
response to interleukin 6
|
GO:0070741 |
10 |
0.256
|
|
|
|
regulation of activation of jak2 kinase activity
|
GO:0010534 |
1 |
0.256
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.253
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.251
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.250
|
Mouse |
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.245
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.243
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.242
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.240
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.237
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.236
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.236
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.235
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.235
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.235
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.235
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.234
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
10 |
0.231
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.229
|
|
|
|
positive regulation of cellular amide metabolic process
|
GO:0034250 |
5 |
0.229
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.228
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.227
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.226
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.226
|
Mouse |
|
|
regulation of interleukin 5 secretion
|
GO:2000662 |
2 |
0.225
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.225
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.218
|
|
|
|
glycosaminoglycan metabolic process
|
GO:0030203 |
34 |
0.217
|
|
|
|
positive regulation of sterol transport
|
GO:0032373 |
9 |
0.217
|
|
|
|
activation induced cell death of t cells
|
GO:0006924 |
10 |
0.217
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.213
|
Mouse |
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.212
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.211
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.211
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.210
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.209
|
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
7 |
0.207
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.206
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.205
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
26 |
0.204
|
|
|
|
regulation of myd88 dependent toll like receptor signaling pathway
|
GO:0034124 |
2 |
0.201
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.199
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.198
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
5 |
0.196
|
|
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
4 |
0.195
|
|
|
|
positive regulation of cd4 positive alpha beta t cell activation
|
GO:2000516 |
16 |
0.195
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
28 |
0.194
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.194
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.194
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.193
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.192
|
|
|
|
regulation of calcidiol 1 monooxygenase activity
|
GO:0060558 |
1 |
0.191
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
8 |
0.191
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.190
|
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.189
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
14 |
0.186
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.184
|
|
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.182
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.182
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.181
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.181
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.179
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.178
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.177
|
|
|
|
type i interferon production
|
GO:0032606 |
29 |
0.176
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.176
|
|
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
7 |
0.176
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.175
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.175
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.173
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.172
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.172
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.170
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.170
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.169
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.168
|
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
5 |
0.167
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.166
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.165
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.163
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.163
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.161
|
|
|
|
regulation of cholesterol efflux
|
GO:0010874 |
13 |
0.161
|
|
|
|
cholesterol efflux
|
GO:0033344 |
24 |
0.160
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.159
|
|
|
|
negative regulation of t helper 1 type immune response
|
GO:0002826 |
5 |
0.159
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.158
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.158
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.155
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.155
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.154
|
Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.154
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.153
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.150
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.149
|
|
|
|
negative regulation of glycolytic process
|
GO:0045820 |
4 |
0.149
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.148
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.147
|
Mouse |
|
|
regulation of cytokine secretion involved in immune response
|
GO:0002739 |
4 |
0.147
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.147
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.147
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.143
|
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.141
|
|
|
|
regulation of interleukin 13 secretion
|
GO:2000665 |
2 |
0.140
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.140
|
|
|
|
negative regulation of alcohol biosynthetic process
|
GO:1902931 |
4 |
0.139
|
|
|
|
negative regulation of stem cell proliferation
|
GO:2000647 |
12 |
0.138
|
|
|
|
negative regulation of interleukin 13 production
|
GO:0032696 |
2 |
0.137
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.136
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.135
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.134
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.134
|
|
|
|
negative regulation of interferon gamma mediated signaling pathway
|
GO:0060336 |
1 |
0.134
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.133
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.131
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.130
|
|
|
|
negative regulation of b cell mediated immunity
|
GO:0002713 |
7 |
0.129
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.129
|
|
|
|
regulation of lipid storage
|
GO:0010883 |
20 |
0.128
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.128
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.128
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.127
|
|
|
|
negative regulation of steroid metabolic process
|
GO:0045939 |
8 |
0.127
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.127
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
30 |
0.125
|
|
|
|
positive regulation of type 2 immune response
|
GO:0002830 |
9 |
0.125
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.124
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.124
|
Mouse |
|
|
cellular response to interleukin 6
|
GO:0071354 |
9 |
0.123
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.123
|
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
14 |
0.123
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.121
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.121
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.120
|
Mouse |
|
|
response to copper ion
|
GO:0046688 |
3 |
0.120
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.120
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.119
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.119
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.118
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.117
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
29 |
0.117
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.115
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.115
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.115
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.115
|
|
|
|
response to uv b
|
GO:0010224 |
5 |
0.114
|
|
|
|
macrophage derived foam cell differentiation
|
GO:0010742 |
6 |
0.114
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
11 |
0.114
|
|
|
|
positive regulation of growth hormone receptor signaling pathway
|
GO:0060399 |
3 |
0.114
|
|
|
|
hyaluronan metabolic process
|
GO:0030212 |
4 |
0.114
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.113
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.112
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.112
|
|
|
|
vitamin metabolic process
|
GO:0006766 |
23 |
0.112
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.111
|
|
|
|
t helper 17 type immune response
|
GO:0072538 |
9 |
0.110
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.109
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.109
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.108
|
|
|
|
positive regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043372 |
14 |
0.108
|
|
|
|
negative regulation of lipid storage
|
GO:0010888 |
6 |
0.108
|
|
