Mus musculus

0 known processes

Rexo2

REX2, RNA exonuclease 2 homolog (S. cerevisiae)

(Aliases: 1810038D15Rik,Sfn,Smfn,AW107347)

Rexo2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.164
amine metabolic process GO:0009308 45 0.144
negative regulation of protein metabolic process GO:0051248 282 0.131
cellular amine metabolic process GO:0044106 44 0.122
regulation of cellular amino acid metabolic process GO:0006521 5 0.084
regulation of cellular ketone metabolic process GO:0010565 66 0.082
negative regulation of cellular protein metabolic process GO:0032269 247 0.077
regulation of cellular amine metabolic process GO:0033238 20 0.076
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.069
modification dependent protein catabolic process GO:0019941 133 0.069
oxidation reduction process GO:0055114 342 0.068
macromolecule catabolic process GO:0009057 281 0.068
apoptotic signaling pathway GO:0097190 306 0.066
protein catabolic process GO:0030163 221 0.063
nucleobase containing small molecule metabolic process GO:0055086 352 0.060
cell type specific apoptotic process GO:0097285 268 0.059
positive regulation of cellular amine metabolic process GO:0033240 5 0.059
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.054
ubiquitin dependent protein catabolic process GO:0006511 129 0.052
cellular ketone metabolic process GO:0042180 84 0.050
regulation of cellular catabolic process GO:0031329 242 0.049
spermatogenesis GO:0007283 284 0.049
cellular modified amino acid metabolic process GO:0006575 63 0.048
carboxylic acid biosynthetic process GO:0046394 86 0.047
regulation of apoptotic signaling pathway GO:2001233 197 0.046
organic acid biosynthetic process GO:0016053 86 0.045
peptidyl amino acid modification GO:0018193 336 0.044
regulation of protein catabolic process GO:0042176 108 0.043
neuron apoptotic process GO:0051402 142 0.041
cation transport GO:0006812 399 0.041
response to reactive oxygen species GO:0000302 56 0.040
negative regulation of phosphate metabolic process GO:0045936 184 0.040
negative regulation of phosphorus metabolic process GO:0010563 184 0.040
response to oxidative stress GO:0006979 123 0.040
negative regulation of molecular function GO:0044092 258 0.040
gland development GO:0048732 330 0.038
organic cyclic compound catabolic process GO:1901361 295 0.038
regulation of transmembrane transport GO:0034762 128 0.038
ribonucleoside metabolic process GO:0009119 245 0.038
cellular response to dna damage stimulus GO:0006974 207 0.038
neuron death GO:0070997 154 0.037
negative regulation of protein modification process GO:0031400 163 0.036
heterocycle catabolic process GO:0046700 280 0.036
regulation of endopeptidase activity GO:0052548 89 0.036
regulation of ion transport GO:0043269 215 0.035
mitochondrion organization GO:0007005 134 0.035
ion transmembrane transport GO:0034220 361 0.034
cellular lipid metabolic process GO:0044255 323 0.034
positive regulation of cell death GO:0010942 224 0.033
male gamete generation GO:0048232 285 0.033
aldehyde catabolic process GO:0046185 4 0.032
organic hydroxy compound metabolic process GO:1901615 203 0.032
aromatic compound catabolic process GO:0019439 286 0.032
negative regulation of phosphorylation GO:0042326 166 0.032
reactive oxygen species metabolic process GO:0072593 84 0.032
positive regulation of protein phosphorylation GO:0001934 242 0.032
nitrogen compound transport GO:0071705 271 0.031
transmembrane transport GO:0055085 412 0.031
cellular macromolecule catabolic process GO:0044265 206 0.031
cellular modified amino acid biosynthetic process GO:0042398 12 0.030
organophosphate catabolic process GO:0046434 232 0.030
muscle cell differentiation GO:0042692 261 0.030
mitotic cell cycle GO:0000278 195 0.030
regulation of membrane potential GO:0042391 192 0.029
ketone catabolic process GO:0042182 3 0.029
regulation of cell cycle GO:0051726 281 0.029
nucleotide metabolic process GO:0009117 332 0.029
purine containing compound metabolic process GO:0072521 311 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
carbohydrate metabolic process GO:0005975 230 0.029
positive regulation of apoptotic process GO:0043065 217 0.028
regulation of kinase activity GO:0043549 249 0.028
regulation of reactive oxygen species metabolic process GO:2000377 40 0.027
positive regulation of apoptotic signaling pathway GO:2001235 95 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.027
positive regulation of programmed cell death GO:0043068 218 0.027
membrane organization GO:0061024 245 0.027
negative regulation of protein phosphorylation GO:0001933 126 0.027
regulation of secretion GO:0051046 274 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.026
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
response to organonitrogen compound GO:0010243 246 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
peptidyl serine modification GO:0018209 83 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
regulation of cytokine production GO:0001817 266 0.024
organelle fission GO:0048285 170 0.024
leukocyte differentiation GO:0002521 342 0.024
alpha amino acid metabolic process GO:1901605 59 0.024
blood circulation GO:0008015 195 0.024
cytokine production GO:0001816 319 0.024
proteasomal protein catabolic process GO:0010498 98 0.023
regulation of removal of superoxide radicals GO:2000121 4 0.023
regulation of hydrolase activity GO:0051336 246 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
regulation of receptor activity GO:0010469 41 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
negative regulation of transferase activity GO:0051348 85 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
positive regulation of protein modification process GO:0031401 299 0.022
regulation of organelle organization GO:0033043 289 0.021
protein localization to organelle GO:0033365 185 0.021
hormone secretion GO:0046879 128 0.021
regulation of leukocyte differentiation GO:1902105 159 0.021
golgi vesicle transport GO:0048193 30 0.021
lipid biosynthetic process GO:0008610 179 0.021
cellular aldehyde metabolic process GO:0006081 12 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
glycoprotein metabolic process GO:0009100 116 0.021
negative regulation of kinase activity GO:0033673 81 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
regulation of hormone levels GO:0010817 211 0.020
regulation of cellular response to stress GO:0080135 159 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
monocarboxylic acid biosynthetic process GO:0072330 61 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
phospholipid metabolic process GO:0006644 87 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
mitotic cell cycle process GO:1903047 159 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
lateral inhibition GO:0046331 1 0.020
response to radiation GO:0009314 165 0.020
cellular protein catabolic process GO:0044257 155 0.020
intracellular protein transport GO:0006886 204 0.020
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
regulation of proteolysis GO:0030162 164 0.019
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
regulation of binding GO:0051098 111 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
cytoplasmic transport GO:0016482 234 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
t cell activation GO:0042110 289 0.019
regulation of neuron death GO:1901214 134 0.019
regulation of neuron apoptotic process GO:0043523 122 0.019
glycosyl compound metabolic process GO:1901657 246 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
actin cytoskeleton organization GO:0030036 220 0.018
negative regulation of neuron death GO:1901215 98 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
regulation of t cell activation GO:0050863 170 0.018
membrane depolarization GO:0051899 64 0.018
renal system development GO:0072001 225 0.018
interleukin 8 production GO:0032637 4 0.018
protein processing GO:0016485 163 0.018
response to inorganic substance GO:0010035 96 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
regulation of translation GO:0006417 71 0.017
response to acid chemical GO:0001101 111 0.017
circulatory system process GO:0003013 197 0.017
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.017
regulation of protein localization GO:0032880 231 0.017
regulation of cell activation GO:0050865 289 0.017
telencephalon development GO:0021537 186 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.016
membrane lipid biosynthetic process GO:0046467 32 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.016
regulation of protein kinase activity GO:0045859 232 0.016
peptide hormone secretion GO:0030072 109 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
mapk cascade GO:0000165 281 0.016
peptide transport GO:0015833 133 0.016
alcohol metabolic process GO:0006066 116 0.016
peptidyl serine phosphorylation GO:0018105 74 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
glycoprotein biosynthetic process GO:0009101 89 0.016
superoxide metabolic process GO:0006801 27 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
striated muscle tissue development GO:0014706 293 0.015
positive regulation of cell development GO:0010720 237 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.015
organelle assembly GO:0070925 177 0.015
regulation of transporter activity GO:0032409 57 0.015
membrane lipid metabolic process GO:0006643 53 0.015
myeloid cell differentiation GO:0030099 233 0.015
inflammatory response GO:0006954 244 0.015
nucleotide catabolic process GO:0009166 217 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
regulation of secretion by cell GO:1903530 249 0.015
cell division GO:0051301 120 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.015
protein localization to membrane GO:0072657 108 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
regulation of anatomical structure size GO:0090066 178 0.014
nuclear division GO:0000280 158 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
regulation of body fluid levels GO:0050878 162 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
muscle tissue development GO:0060537 308 0.014
lymphocyte proliferation GO:0046651 164 0.014
pyridine containing compound catabolic process GO:0072526 4 0.014
alpha amino acid biosynthetic process GO:1901607 15 0.014
wnt signaling pathway GO:0016055 188 0.014
small molecule biosynthetic process GO:0044283 132 0.014
positive regulation of interleukin 8 production GO:0032757 2 0.014
homeostasis of number of cells GO:0048872 210 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
regulation of interleukin 8 production GO:0032677 3 0.014
t cell differentiation GO:0030217 174 0.014
kidney development GO:0001822 213 0.014
regulation of vesicle mediated transport GO:0060627 139 0.013
response to organic cyclic compound GO:0014070 198 0.013
regulation of protein transport GO:0051223 163 0.013
cellular protein complex assembly GO:0043623 116 0.013
forebrain development GO:0030900 302 0.013
camera type eye development GO:0043010 266 0.013
negative regulation of protein transport GO:0051224 46 0.013
amide transport GO:0042886 138 0.013
cellular homeostasis GO:0019725 240 0.013
carbohydrate homeostasis GO:0033500 128 0.013
nucleoside diphosphate catabolic process GO:0009134 4 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
cytokinetic process GO:0032506 2 0.013
trna metabolic process GO:0006399 11 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
urogenital system development GO:0001655 261 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
regulation of map kinase activity GO:0043405 120 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
peptide secretion GO:0002790 114 0.012
microtubule based process GO:0007017 236 0.012
cell adhesion GO:0007155 329 0.012
skin development GO:0043588 220 0.012
glucose homeostasis GO:0042593 128 0.012
cation transmembrane transport GO:0098655 266 0.012
negative regulation of protein catabolic process GO:0042177 36 0.012
protein oxidation GO:0018158 2 0.012
response to monosaccharide GO:0034284 67 0.012
regulation of homeostatic process GO:0032844 182 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
lymphocyte differentiation GO:0030098 242 0.012
protein polymerization GO:0051258 57 0.012
catecholamine uptake involved in synaptic transmission GO:0051934 4 0.012
synaptic transmission GO:0007268 329 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
spermatid differentiation GO:0048515 115 0.012
regulation of actin cytoskeleton organization GO:0032956 84 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
regulation of transferase activity GO:0051338 263 0.012
divalent metal ion transport GO:0070838 172 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
cell substrate adhesion GO:0031589 130 0.012
macromolecule methylation GO:0043414 120 0.012
negative regulation of immune system process GO:0002683 209 0.012
organ growth GO:0035265 117 0.012
cellular response to peptide GO:1901653 92 0.012
nucleoside catabolic process GO:0009164 206 0.012
dephosphorylation GO:0016311 129 0.012
sensory organ morphogenesis GO:0090596 242 0.012
respiratory system development GO:0060541 190 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.012
glycerolipid metabolic process GO:0046486 122 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
insulin secretion GO:0030073 89 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.011
glycosylation GO:0070085 62 0.011
neural precursor cell proliferation GO:0061351 121 0.011
methylation GO:0032259 134 0.011
response to peptide GO:1901652 136 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of cell projection organization GO:0031344 206 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
positive regulation of secretion GO:0051047 130 0.011
regulation of t cell differentiation GO:0045580 83 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
leukocyte proliferation GO:0070661 172 0.011
cellular response to lipid GO:0071396 145 0.011
phagocytosis GO:0006909 66 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
protein ubiquitination GO:0016567 171 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
extracellular matrix organization GO:0030198 147 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
regulation of glutamate receptor signaling pathway GO:1900449 16 0.011
protein secretion GO:0009306 111 0.011
myotube differentiation GO:0014902 105 0.011
response to nutrient levels GO:0031667 109 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
response to testosterone GO:0033574 3 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
cellular chemical homeostasis GO:0055082 215 0.011
positive regulation of proteolysis GO:0045862 85 0.011
protein dna complex subunit organization GO:0071824 28 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
regulation of multi organism process GO:0043900 111 0.011
regulation of peptidyl serine phosphorylation GO:0033135 39 0.011
response to extracellular stimulus GO:0009991 127 0.011
regulation of cell motility GO:2000145 236 0.010
positive regulation of cellular respiration GO:1901857 3 0.010
localization within membrane GO:0051668 4 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
regulation of intracellular transport GO:0032386 159 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
stress activated mapk cascade GO:0051403 80 0.010
protein modification by small protein conjugation GO:0032446 187 0.010
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.010
response to hydrogen peroxide GO:0042542 32 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
learning or memory GO:0007611 148 0.010
regulation of neuron differentiation GO:0045664 281 0.010
regulation of feeding behavior GO:0060259 3 0.010
regulation of inflammatory response GO:0050727 147 0.010
regulation of protein secretion GO:0050708 82 0.010
immune effector process GO:0002252 321 0.010

Rexo2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.027
disease of anatomical entity DOID:7 0 0.027
central nervous system disease DOID:331 0 0.020
neurodegenerative disease DOID:1289 0 0.019
immune system disease DOID:2914 0 0.016
musculoskeletal system disease DOID:17 0 0.011