|
|
establishment or maintenance of actin cytoskeleton polarity
|
GO:0030950 |
1 |
0.991
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.979
|
|
|
|
positive regulation of tor signaling
|
GO:0032008 |
3 |
0.978
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.974
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.967
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.944
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.941
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.938
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.928
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.902
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.886
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.884
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.875
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.862
|
|
|
|
membrane lipid biosynthetic process
|
GO:0046467 |
32 |
0.821
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.794
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
17 |
0.791
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.788
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.781
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.779
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.777
|
Human |
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.771
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.746
|
Human |
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.724
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.720
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.694
|
|
|
|
regulation of rac gtpase activity
|
GO:0032314 |
13 |
0.674
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.661
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.656
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.650
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.646
|
|
|
|
negative regulation of nfat protein import into nucleus
|
GO:0051534 |
3 |
0.644
|
|
|
|
histone h3 k4 trimethylation
|
GO:0080182 |
5 |
0.636
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.618
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.611
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.606
|
|
|
|
regulation of rac protein signal transduction
|
GO:0035020 |
19 |
0.605
|
|
|
|
histone methylation
|
GO:0016571 |
71 |
0.590
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.576
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.572
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.563
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.557
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.556
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.554
|
Fly |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.544
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.534
|
Worm |
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.508
|
|
|
|
regulation of sphingolipid biosynthetic process
|
GO:0090153 |
1 |
0.499
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.497
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.497
|
|
|
|
sphingolipid biosynthetic process
|
GO:0030148 |
26 |
0.495
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.485
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.463
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.450
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.449
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.447
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.443
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.443
|
Fly |
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.433
|
|
|
|
tor signaling
|
GO:0031929 |
21 |
0.430
|
Human |
|
|
syncytium formation
|
GO:0006949 |
43 |
0.429
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.423
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.422
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.413
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.407
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.391
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.388
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.385
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.383
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.382
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.378
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.373
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.370
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.366
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.364
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.359
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.352
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.350
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.350
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.339
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.338
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.329
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.324
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.321
|
|
|
|
transcription from rna polymerase iii promoter
|
GO:0006383 |
3 |
0.311
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.311
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.307
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.303
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.296
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.284
|
|
|
|
macroautophagy
|
GO:0016236 |
21 |
0.280
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.274
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.273
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.272
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.270
|
|
|
|
lipid phosphorylation
|
GO:0046834 |
25 |
0.266
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.253
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.252
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.249
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.249
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.247
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.247
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.243
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.236
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.232
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.231
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.222
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.216
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.216
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.215
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.214
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.214
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.213
|
Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.212
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.212
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.210
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.206
|
|
|
|
positive regulation of transcription from rna polymerase iii promoter
|
GO:0045945 |
1 |
0.206
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.206
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.205
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.204
|
|
|
|
negative regulation of macroautophagy
|
GO:0016242 |
5 |
0.202
|
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.199
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.197
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.197
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.193
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.191
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.189
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.189
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.189
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.188
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.188
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.181
|
Worm |
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.179
|
|
|
|
insulin like growth factor receptor signaling pathway
|
GO:0048009 |
21 |
0.177
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.173
|
|
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
13 |
0.171
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.170
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.168
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.165
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.163
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.160
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.160
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.160
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.159
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.159
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.158
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.155
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.155
|
|
|
|
negative regulation of fibroblast migration
|
GO:0010764 |
2 |
0.155
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.154
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.152
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.152
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.149
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.148
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.147
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.146
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.146
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.143
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.142
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.142
|
Worm |
|
|
oogenesis
|
GO:0048477 |
56 |
0.141
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.140
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.140
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.139
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.139
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.138
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.137
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.137
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.137
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.136
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.134
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.133
|
Fly |
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.132
|
|
|
|
peptidyl lysine methylation
|
GO:0018022 |
29 |
0.131
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.130
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.130
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.129
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.129
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.128
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.127
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.126
|
|
|
|
transcription from rna polymerase i promoter
|
GO:0006360 |
13 |
0.126
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.125
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.125
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.124
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.124
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.124
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.123
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.123
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.123
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.122
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.122
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.120
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.120
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.117
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.116
|
|
|
|
regulation of transcription from rna polymerase iii promoter
|
GO:0006359 |
2 |
0.116
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.116
|
|
|
|
peptidyl lysine trimethylation
|
GO:0018023 |
12 |
0.115
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.115
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.115
|
Fly |
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
11 |
0.114
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.114
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.113
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.113
|
Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.113
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
6 |
0.112
|
Fly |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.112
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.111
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.111
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.109
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.109
|
|
|
|
negative regulation of synaptic vesicle exocytosis
|
GO:2000301 |
3 |
0.109
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.108
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.106
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.106
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.106
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.105
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.103
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.103
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.102
|
|
|
|
histone h3 k4 methylation
|
GO:0051568 |
23 |
0.102
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.102
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.102
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.101
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.099
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.099
|
|
|
|
negative regulation of synaptic vesicle transport
|
GO:1902804 |
3 |
0.099
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.097
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.096
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
18 |
0.096
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.095
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.093
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.093
|
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.093
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.093
|
Fly |
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.091
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.091
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.091
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.091
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.090
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.089
|
|
|
|
midbrain development
|
GO:0030901 |
35 |
0.089
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.088
|
|
|
|
phosphatidylinositol phosphorylation
|
GO:0046854 |
23 |
0.087
|
|
|
|
negative regulation of autophagy
|
GO:0010507 |
9 |
0.087
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.086
|
|
|
|
regulation of macroautophagy
|
GO:0016241 |
12 |
0.086
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.085
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.085
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.083
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.083
|
|
|
|
regulation of histone methylation
|
GO:0031060 |
30 |
0.082
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.082
|
|
|
|
histone h3 k9 trimethylation
|
GO:0036124 |
6 |
0.081
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.080
|
Worm |
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.080
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.080
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.079
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.079
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.078
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.077
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.077
|
Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.076
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.076
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.075
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.074
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.073
|
Fly |
|
|
pancreas development
|
GO:0031016 |
57 |
0.073
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.073
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.073
|
Fly |
|
|
histone h4 k20 methylation
|
GO:0034770 |
8 |
0.073
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.072
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.072
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.072
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
24 |
0.071
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.071
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.070
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.070
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
15 |
0.070
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.069
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.069
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.069
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.068
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.068
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.067
|
|
|
|
ventricular septum development
|
GO:0003281 |
42 |
0.066
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.066
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.066
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.065
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.065
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.065
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.064
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.064
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.062
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.062
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.061
|
|
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
26 |
0.061
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.061
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.060
|
|
|
|
intermediate filament based process
|
GO:0045103 |
27 |
0.060
|
|
|
|
translation
|
GO:0006412 |
93 |
0.060
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.059
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.059
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.058
|
|
|
|
regulation of myelination
|
GO:0031641 |
20 |
0.057
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.057
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.056
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.056
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.056
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.056
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.055
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.055
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.055
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.055
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.055
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
25 |
0.055
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.055
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.054
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.054
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.054
|
|
|
|
positive regulation of transcription by galactose
|
GO:0000411 |
1 |
0.054
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.054
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.053
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.053
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.052
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.052
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.051
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.051
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.051
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.051
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.051
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.051
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.051
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
18 |
0.050
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.049
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.049
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.049
|
|
|
|
positive regulation of stress fiber assembly
|
GO:0051496 |
9 |
0.049
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.048
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.048
|
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
35 |
0.048
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.048
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.047
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.047
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.047
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.046
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.046
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.046
|
Fly |
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.046
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.046
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.046
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.046
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.046
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.045
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.045
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.045
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.045
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.045
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
3 |
0.045
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.045
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.045
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.044
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.044
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.044
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.044
|
|
|
|
substantia nigra development
|
GO:0021762 |
2 |
0.043
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.043
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.043
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
5 |
0.043
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.043
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.042
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.042
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.042
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.042
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.042
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.041
|
Fly |
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.041
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.041
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
23 |
0.041
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.041
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.041
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.041
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.041
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.041
|
|
|
|
translational initiation
|
GO:0006413 |
24 |
0.040
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.040
|
|
|
|
regulation of nfat protein import into nucleus
|
GO:0051532 |
4 |
0.040
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.040
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
39 |
0.040
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.040
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.040
|
|
|
|
regulation of autophagic vacuole assembly
|
GO:2000785 |
4 |
0.039
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.039
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.039
|
|
|
|
sensory system development
|
GO:0048880 |
3 |
0.039
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.039
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.038
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.038
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.038
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.038
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
11 |
0.038
|
Worm |
|
|
carbon catabolite activation of transcription from rna polymerase ii promoter
|
GO:0000436 |
4 |
0.038
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.038
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.038
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.037
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.037
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.037
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.037
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.037
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.037
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.037
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.037
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.036
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.036
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.036
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.036
|
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
7 |
0.036
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.035
|
|
|
|
neural nucleus development
|
GO:0048857 |
22 |
0.035
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.035
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.035
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.035
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.035
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.034
|
|
|
|
regulation of vacuole organization
|
GO:0044088 |
4 |
0.034
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.034
|
|
|
|
positive regulation of lamellipodium assembly
|
GO:0010592 |
2 |
0.034
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.034
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.034
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.034
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.034
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
8 |
0.034
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.034
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.033
|
|
|
|
dna dealkylation
|
GO:0035510 |
11 |
0.033
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.033
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.033
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.033
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
54 |
0.033
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.033
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.033
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.033
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.033
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.033
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.033
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.033
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.032
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.032
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.032
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
27 |
0.032
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.032
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.032
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.032
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.032
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.032
|
|
|
|
positive regulation of lamellipodium organization
|
GO:1902745 |
3 |
0.031
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.031
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.031
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.031
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.031
|
|
|
|
ruffle organization
|
GO:0031529 |
16 |
0.031
|
|
|
|
regulation of peptidyl threonine phosphorylation
|
GO:0010799 |
12 |
0.031
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.031
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.031
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.031
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.031
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.031
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.031
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.030
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.030
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.030
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.030
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.030
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.030
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.030
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.030
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.030
|
|
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
61 |
0.030
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.030
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.030
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.030
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.029
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.029
|
|
|
|
dna modification
|
GO:0006304 |
50 |
0.029
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.029
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.029
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.029
|
|
|
|
regulation of mitosis
|
GO:0007088 |
29 |
0.029
|
|
|
|
cell differentiation involved in embryonic placenta development
|
GO:0060706 |
26 |
0.029
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.029
|
|
