Mus musculus

26 known processes

Rnaseh2a

ribonuclease H2, large subunit

(Aliases: 2400006P09Rik,RNHL,RNASEHI,RNHIA)

Rnaseh2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleoside phosphate metabolic process GO:0006753 338 0.109
dna metabolic process GO:0006259 303 0.107
heterocycle catabolic process GO:0046700 280 0.106
nucleobase containing small molecule metabolic process GO:0055086 352 0.092
nucleotide metabolic process GO:0009117 332 0.091
cellular response to dna damage stimulus GO:0006974 207 0.083
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.081
aromatic compound catabolic process GO:0019439 286 0.075
nucleoside triphosphate metabolic process GO:0009141 230 0.075
cellular amino acid metabolic process GO:0006520 103 0.063
purine ribonucleoside metabolic process GO:0046128 241 0.062
purine containing compound metabolic process GO:0072521 311 0.060
organic cyclic compound catabolic process GO:1901361 295 0.059
purine ribonucleotide metabolic process GO:0009150 290 0.056
iron sulfur cluster assembly GO:0016226 3 0.055
cellular ketone metabolic process GO:0042180 84 0.054
regulation of cellular ketone metabolic process GO:0010565 66 0.052
purine nucleoside triphosphate metabolic process GO:0009144 226 0.051
nucleoside monophosphate metabolic process GO:0009123 85 0.051
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
positive regulation of cellular amine metabolic process GO:0033240 5 0.046
nucleoside metabolic process GO:0009116 246 0.046
cellular amine metabolic process GO:0044106 44 0.046
cellular nitrogen compound catabolic process GO:0044270 280 0.046
ribonucleotide metabolic process GO:0009259 291 0.045
ribonucleoside metabolic process GO:0009119 245 0.044
dna dependent dna replication GO:0006261 24 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
chromatin organization GO:0006325 206 0.041
ribonucleotide catabolic process GO:0009261 208 0.040
microtubule based process GO:0007017 236 0.040
ribose phosphate metabolic process GO:0019693 291 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.038
cellular macromolecule catabolic process GO:0044265 206 0.036
protein maturation GO:0051604 176 0.035
purine nucleotide metabolic process GO:0006163 302 0.035
amine metabolic process GO:0009308 45 0.035
purine ribonucleoside catabolic process GO:0046130 205 0.034
nucleoside phosphate biosynthetic process GO:1901293 79 0.034
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
purine nucleoside monophosphate metabolic process GO:0009126 81 0.032
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.030
organelle fission GO:0048285 170 0.030
protein processing GO:0016485 163 0.030
glycosyl compound metabolic process GO:1901657 246 0.030
cation transport GO:0006812 399 0.029
cellular homeostasis GO:0019725 240 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.029
regulation of transferase activity GO:0051338 263 0.029
meiotic cell cycle process GO:1903046 77 0.029
organonitrogen compound catabolic process GO:1901565 264 0.029
purine containing compound catabolic process GO:0072523 213 0.029
protein modification by small protein conjugation GO:0032446 187 0.029
transmembrane transport GO:0055085 412 0.028
negative regulation of molecular function GO:0044092 258 0.028
telomere maintenance via telomerase GO:0007004 1 0.028
organelle assembly GO:0070925 177 0.027
macromolecule catabolic process GO:0009057 281 0.027
negative regulation of phosphorylation GO:0042326 166 0.027
organic hydroxy compound metabolic process GO:1901615 203 0.026
mitotic cell cycle process GO:1903047 159 0.026
protein localization to organelle GO:0033365 185 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
regulation of membrane potential GO:0042391 192 0.024
meiotic nuclear division GO:0007126 115 0.024
regulation of cell cycle phase transition GO:1901987 77 0.024
oxidation reduction process GO:0055114 342 0.023
positive regulation of protein modification process GO:0031401 299 0.023
response to oxidative stress GO:0006979 123 0.023
organophosphate catabolic process GO:0046434 232 0.023
regulation of protein localization GO:0032880 231 0.023
cellular lipid metabolic process GO:0044255 323 0.022
regulation of organelle organization GO:0033043 289 0.022
spermatogenesis GO:0007283 284 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
t cell activation GO:0042110 289 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.021
peptidyl amino acid modification GO:0018193 336 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
nucleotide biosynthetic process GO:0009165 78 0.021
ribonucleoside monophosphate metabolic process GO:0009161 80 0.021
negative regulation of cell cycle process GO:0010948 69 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
dna repair GO:0006281 107 0.020
nitrogen compound transport GO:0071705 271 0.020
histone modification GO:0016570 159 0.019
nucleotide catabolic process GO:0009166 217 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
regulation of cell cycle process GO:0010564 160 0.019
inflammatory response GO:0006954 244 0.019
purine nucleotide biosynthetic process GO:0006164 65 0.019
leukocyte proliferation GO:0070661 172 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
response to inorganic substance GO:0010035 96 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
ion transmembrane transport GO:0034220 361 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
nucleoside catabolic process GO:0009164 206 0.018
purine containing compound biosynthetic process GO:0072522 70 0.018
regulation of cellular response to stress GO:0080135 159 0.018
cellular protein complex assembly GO:0043623 116 0.018
regulation of hydrolase activity GO:0051336 246 0.018
mitochondrion organization GO:0007005 134 0.018
dephosphorylation GO:0016311 129 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
negative regulation of cell cycle GO:0045786 123 0.017
germ cell development GO:0007281 185 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
nuclear division GO:0000280 158 0.017
leukocyte differentiation GO:0002521 342 0.016
blastocyst development GO:0001824 80 0.016
deoxyribonucleotide catabolic process GO:0009264 5 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
regulation of intracellular transport GO:0032386 159 0.016
response to oxygen levels GO:0070482 62 0.016
nuclear transport GO:0051169 139 0.015
lymphocyte proliferation GO:0046651 164 0.015
microtubule nucleation GO:0007020 2 0.015
male gamete generation GO:0048232 285 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
negative regulation of protein maturation GO:1903318 79 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
meiosis i GO:0007127 60 0.015
mitotic cell cycle GO:0000278 195 0.015
anatomical structure homeostasis GO:0060249 145 0.015
positive regulation of cell death GO:0010942 224 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
protein ubiquitination GO:0016567 171 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
covalent chromatin modification GO:0016569 163 0.014
cell division GO:0051301 120 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
cytokine production GO:0001816 319 0.014
positive regulation of transferase activity GO:0051347 167 0.014
sister chromatid segregation GO:0000819 20 0.014
adult behavior GO:0030534 135 0.014
regulation of cell cycle GO:0051726 281 0.014
regulation of protein transport GO:0051223 163 0.013
apoptotic signaling pathway GO:0097190 306 0.013
immune effector process GO:0002252 321 0.013
gtp catabolic process GO:0006184 143 0.013
meiotic cell cycle GO:0051321 122 0.013
apoptotic mitochondrial changes GO:0008637 48 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
response to organic cyclic compound GO:0014070 198 0.012
male gonad development GO:0008584 88 0.012
alcohol metabolic process GO:0006066 116 0.012
t cell proliferation GO:0042098 120 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
metal ion homeostasis GO:0055065 189 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
regulation of dna damage checkpoint GO:2000001 3 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
t cell differentiation GO:0030217 174 0.012
cell type specific apoptotic process GO:0097285 268 0.012
trna wobble uridine modification GO:0002098 2 0.012
cellular chemical homeostasis GO:0055082 215 0.012
histone threonine phosphorylation GO:0035405 1 0.012
atp metabolic process GO:0046034 75 0.012
regulation of defense response GO:0031347 233 0.012
ribose phosphate biosynthetic process GO:0046390 59 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
cytoplasmic transport GO:0016482 234 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
wnt signaling pathway GO:0016055 188 0.011
cation transmembrane transport GO:0098655 266 0.011
dna replication GO:0006260 52 0.011
response to reactive oxygen species GO:0000302 56 0.011
lymphocyte differentiation GO:0030098 242 0.011
mitotic nuclear division GO:0007067 48 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
regulation of proteolysis GO:0030162 164 0.011
negative regulation of protein processing GO:0010955 79 0.011
regulation of cell cycle checkpoint GO:1901976 9 0.011
hindbrain development GO:0030902 128 0.011
multicellular organism growth GO:0035264 161 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
regulation of kinase activity GO:0043549 249 0.011
inner cell mass cell proliferation GO:0001833 15 0.011
dna catabolic process endonucleolytic GO:0000737 15 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
intracellular protein transport GO:0006886 204 0.011
cellular modified amino acid metabolic process GO:0006575 63 0.011
regulation of protein processing GO:0070613 96 0.011
synaptic transmission GO:0007268 329 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
regulation of cell migration GO:0030334 219 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
embryonic organ morphogenesis GO:0048562 276 0.010
regulation of response to wounding GO:1903034 189 0.010
regulation of cell motility GO:2000145 236 0.010
regulation of ion transport GO:0043269 215 0.010
sensory perception GO:0007600 245 0.010
regulation of protein complex assembly GO:0043254 83 0.010
protein localization to nucleus GO:0034504 121 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
regulation of multi organism process GO:0043900 111 0.010

Rnaseh2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.032
inherited metabolic disorder DOID:655 0 0.032
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
central nervous system disease DOID:331 0 0.015
neurodegenerative disease DOID:1289 0 0.015