Mus musculus

74 known processes

Robo2

roundabout homolog 2 (Drosophila)

(Aliases: D230004I22Rik,mKIAA1568,9430089E08Rik,2600013A04Rik,BB097918)

Robo2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dorsal ventral axon guidance GO:0033563 3 1.000
Worm
formation of organ boundary GO:0010160 1 0.998
Fly
regulation of negative chemotaxis GO:0050923 1 0.988
Human
negative chemotaxis GO:0050919 14 0.976
Human Mouse
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.958
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.957
negative regulation of behavior GO:0048521 14 0.946
Human Zebrafish
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.940
chemokine mediated signaling pathway GO:0070098 17 0.925
roundabout signaling pathway GO:0035385 0 0.916
Fly
mammary duct terminal end bud growth GO:0060763 5 0.889
Mouse
cardioblast migration GO:0003260 1 0.874
negative regulation of chemotaxis GO:0050922 11 0.785
Human Zebrafish
cell migration to the midline involved in heart development GO:0003318 1 0.779
negative regulation of osteoclast differentiation GO:0045671 12 0.712
mesodermal cell migration GO:0008078 4 0.693
negative regulation of axon extension GO:0030517 19 0.630
Zebrafish
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.621
Zebrafish
central nervous system projection neuron axonogenesis GO:0021952 21 0.617
Zebrafish
central nervous system neuron axonogenesis GO:0021955 28 0.549
Zebrafish
leukocyte differentiation GO:0002521 342 0.539
negative regulation of axon guidance GO:1902668 8 0.525
Zebrafish
negative regulation of leukocyte differentiation GO:1902106 51 0.517
cell migration involved in heart formation GO:0060974 1 0.475
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.472
neuron projection extension GO:1990138 64 0.454
Zebrafish
renal system development GO:0072001 225 0.439
olfactory bulb interneuron development GO:0021891 7 0.426
negative regulation of response to cytokine stimulus GO:0060761 9 0.417
epithelial tube morphogenesis GO:0060562 303 0.416
Mouse
substrate dependent cell migration GO:0006929 18 0.406
negative regulation of endothelial cell migration GO:0010596 4 0.399
regulation of cellular component size GO:0032535 121 0.395
Zebrafish
cell cell adhesion GO:0098609 41 0.390
Human
negative regulation of neuron projection development GO:0010977 50 0.385
Zebrafish
urogenital system development GO:0001655 261 0.373
nucleus localization GO:0051647 20 0.369
negative regulation of cell proliferation GO:0008285 296 0.366
Mouse
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.365
Human
regulation of cell size GO:0008361 72 0.358
Zebrafish
regulation of anatomical structure size GO:0090066 178 0.345
Zebrafish
negative regulation of cell growth GO:0030308 44 0.333
Zebrafish
kidney development GO:0001822 213 0.328
regulation of axon extension GO:0030516 43 0.322
Zebrafish
negative regulation of protein metabolic process GO:0051248 282 0.321
myeloid leukocyte differentiation GO:0002573 119 0.313
cell recognition GO:0008037 83 0.301
telencephalon development GO:0021537 186 0.300
developmental cell growth GO:0048588 84 0.298
Zebrafish
motor neuron axon guidance GO:0008045 26 0.298
Fly
central nervous system neuron development GO:0021954 67 0.294
forebrain development GO:0030900 302 0.292
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.288
Human Zebrafish
skeletal system development GO:0001501 356 0.285
mammary gland epithelium development GO:0061180 65 0.284
Mouse
regulation of monocyte chemotaxis GO:0090025 3 0.276
axon extension involved in axon guidance GO:0048846 14 0.275
Zebrafish
establishment of organelle localization GO:0051656 122 0.273
bone marrow development GO:0048539 3 0.273
regulation of leukocyte differentiation GO:1902105 159 0.272
olfactory bulb interneuron differentiation GO:0021889 12 0.272
cytokine mediated signaling pathway GO:0019221 115 0.265
telencephalon cell migration GO:0022029 55 0.264
forebrain cell migration GO:0021885 58 0.264
actin polymerization or depolymerization GO:0008154 54 0.255
gonad development GO:0008406 141 0.253
Human Fly
cell adhesion GO:0007155 329 0.252
Human Fly
cerebral cortex cell migration GO:0021795 44 0.251
actin filament organization GO:0007015 113 0.251
cell migration involved in gastrulation GO:0042074 13 0.246
mesonephros development GO:0001823 97 0.244
heart morphogenesis GO:0003007 178 0.242
Fly
actin filament polymerization GO:0030041 44 0.238
regulation of myeloid leukocyte differentiation GO:0002761 58 0.237
cerebral cortex tangential migration GO:0021800 7 0.235
ureteric bud development GO:0001657 94 0.233
positive regulation of cell adhesion GO:0045785 80 0.222
Fly
female gonad development GO:0008585 71 0.222
Human
regulation of cell adhesion GO:0030155 154 0.218
Fly
regulation of axon guidance GO:1902667 13 0.216
Zebrafish
regulation of osteoclast differentiation GO:0045670 36 0.215
regulation of inflammatory response GO:0050727 147 0.211
axonogenesis GO:0007409 274 0.210
central nervous system neuron differentiation GO:0021953 162 0.209
axon guidance GO:0007411 141 0.207
embryonic heart tube development GO:0035050 65 0.206
Fly
neuron migration GO:0001764 122 0.205
Mouse Worm Fly
dendrite development GO:0016358 115 0.205
Fly
convergent extension involved in organogenesis GO:0060029 7 0.202
regulation of hydrolase activity GO:0051336 246 0.198
olfactory lobe development GO:0021988 32 0.196
gland development GO:0048732 330 0.194
Mouse Fly
regulation of actin polymerization or depolymerization GO:0008064 45 0.194
mammary gland morphogenesis GO:0060443 54 0.193
Mouse
commissural neuron axon guidance GO:0071679 8 0.192
Mouse
regulation of extent of cell growth GO:0061387 52 0.190
Zebrafish
lateral inhibition GO:0046331 1 0.187
regulation of chemotaxis GO:0050920 53 0.186
Human Zebrafish
negative regulation of immune system process GO:0002683 209 0.186
heart formation GO:0060914 16 0.184
olfactory bulb development GO:0021772 30 0.182
cell cell signaling involved in cell fate commitment GO:0045168 35 0.181
mesonephric epithelium development GO:0072163 94 0.180
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.179
Human
kidney epithelium development GO:0072073 121 0.179
regulation of response to cytokine stimulus GO:0060759 23 0.178
cellular response to cytokine stimulus GO:0071345 189 0.177
developmental growth involved in morphogenesis GO:0060560 138 0.176
Zebrafish Mouse
single organismal cell cell adhesion GO:0016337 131 0.175
Fly
positive regulation of cell projection organization GO:0031346 95 0.174
Human
osteoclast differentiation GO:0030316 62 0.171
actin cytoskeleton organization GO:0030036 220 0.167
cellular amino acid metabolic process GO:0006520 103 0.166
development of primary sexual characteristics GO:0045137 143 0.164
Human Fly
regulation of actin filament polymerization GO:0030833 38 0.163
branching morphogenesis of an epithelial tube GO:0048754 159 0.161
cerebral cortex development GO:0021987 86 0.158
negative regulation of mammary gland epithelial cell proliferation GO:0033600 3 0.157
amine metabolic process GO:0009308 45 0.155
digestive tract morphogenesis GO:0048546 147 0.154
regulation of cellular amine metabolic process GO:0033238 20 0.153
mammary gland duct morphogenesis GO:0060603 38 0.152
Mouse
positive regulation of apoptotic process GO:0043065 217 0.152
rhythmic process GO:0048511 174 0.151
Human Fly
cell fate commitment GO:0045165 210 0.151
Fly
salivary gland development GO:0007431 37 0.149
Fly
regulation of neuron differentiation GO:0045664 281 0.149
Human Zebrafish Fly
cell growth GO:0016049 130 0.148
Zebrafish
regulation of cell projection organization GO:0031344 206 0.147
Human Zebrafish Fly
ameboidal type cell migration GO:0001667 128 0.146
Fly
positive regulation of behavior GO:0048520 40 0.146
smooth muscle cell chemotaxis GO:0071670 2 0.142
neuromuscular process GO:0050905 99 0.141
Fly
mesoderm morphogenesis GO:0048332 64 0.140
negative regulation of cell projection organization GO:0031345 56 0.140
Zebrafish
mesoderm development GO:0007498 100 0.139
regulation of actin filament length GO:0030832 45 0.139
protein maturation GO:0051604 176 0.138
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.138
Human
bone development GO:0060348 120 0.135
negative regulation of molecular function GO:0044092 258 0.132
retinal ganglion cell axon guidance GO:0031290 18 0.130
positive regulation of programmed cell death GO:0043068 218 0.130
gliogenesis GO:0042063 141 0.130
outflow tract morphogenesis GO:0003151 53 0.129
Fly
single organism cell adhesion GO:0098602 156 0.129
Fly
negative regulation of growth GO:0045926 99 0.128
Zebrafish
epithelium migration GO:0090132 63 0.128
Fly
regulation of protein complex assembly GO:0043254 83 0.128
forebrain generation of neurons GO:0021872 63 0.127
chemotaxis GO:0006935 247 0.127
neuron recognition GO:0008038 25 0.126
regulation of cell migration GO:0030334 219 0.123
Mouse Fly
digestive tract development GO:0048565 190 0.123
positive regulation of chemotaxis GO:0050921 38 0.121
regulation of cellular component biogenesis GO:0044087 181 0.119
Zebrafish
positive regulation of neuron projection development GO:0010976 79 0.118
Human
tissue migration GO:0090130 68 0.118
Fly
regulation of lamellipodium assembly GO:0010591 3 0.118
leukocyte migration GO:0050900 124 0.117
regulation of cellular amino acid metabolic process GO:0006521 5 0.112
response to alcohol GO:0097305 48 0.109
positive regulation of cell development GO:0010720 237 0.109
Human
formation of anatomical boundary GO:0048859 6 0.109
Fly
regulation of cell growth GO:0001558 91 0.106
Zebrafish
regulation of neuron projection development GO:0010975 169 0.106
Human Zebrafish Fly
negative regulation of cellular amine metabolic process GO:0033239 1 0.105
spinal cord development GO:0021510 81 0.105
negative regulation of cell motility GO:2000146 61 0.103
Mouse
regulation of endopeptidase activity GO:0052548 89 0.103
glial cell migration GO:0008347 7 0.103
exocrine system development GO:0035272 45 0.102
Fly
gastrulation GO:0007369 116 0.101
negative regulation of myeloid cell differentiation GO:0045638 38 0.101
positive regulation of neuron differentiation GO:0045666 141 0.100
Human
response to organic cyclic compound GO:0014070 198 0.098
metanephros development GO:0001656 79 0.097
negative regulation of neuron differentiation GO:0045665 101 0.097
Zebrafish
regionalization GO:0003002 337 0.095
Fly
forebrain neuron differentiation GO:0021879 52 0.094
negative regulation of smooth muscle cell migration GO:0014912 2 0.092
regulation of cell motility GO:2000145 236 0.090
Mouse Fly
convergent extension GO:0060026 14 0.088
positive regulation of nervous system development GO:0051962 221 0.087
Human
positive regulation of cell death GO:0010942 224 0.086
digestive system development GO:0055123 200 0.085
myeloid cell differentiation GO:0030099 233 0.083
response to steroid hormone GO:0048545 56 0.082
negative regulation of cytoskeleton organization GO:0051494 36 0.082
blood vessel endothelial cell migration GO:0043534 23 0.082
stem cell differentiation GO:0048863 268 0.082
Fly
neuron projection guidance GO:0097485 141 0.082
epithelial cell migration GO:0010631 63 0.080
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.079
cardiac cell fate specification GO:0060912 2 0.078
Fly
cellular response to hormone stimulus GO:0032870 150 0.078
Human
formation of primary germ layer GO:0001704 77 0.076
anatomical structure homeostasis GO:0060249 145 0.073
Fly
ovulation cycle GO:0042698 59 0.073
Human
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.073
negative regulation of cellular protein metabolic process GO:0032269 247 0.073
organelle localization GO:0051640 179 0.071
pallium development GO:0021543 120 0.070
angiogenesis GO:0001525 201 0.070
vascular process in circulatory system GO:0003018 62 0.070
apoptotic signaling pathway GO:0097190 306 0.070
regulation of epithelial cell migration GO:0010632 35 0.068
Fly
negative regulation of organelle organization GO:0010639 90 0.067
negative regulation of phosphorylation GO:0042326 166 0.067
regulation of proteolysis GO:0030162 164 0.066
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.066
anterior posterior axon guidance GO:0033564 5 0.065
Zebrafish
cell chemotaxis GO:0060326 81 0.065
granulocyte migration GO:0097530 43 0.065
regulation of cytoskeleton organization GO:0051493 122 0.064
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.064
cell migration involved in sprouting angiogenesis GO:0002042 9 0.063
smooth muscle cell migration GO:0014909 10 0.063
blood circulation GO:0008015 195 0.063
positive regulation of axon extension GO:0045773 20 0.063
negative regulation of cell migration GO:0030336 59 0.062
Mouse
multicellular organismal signaling GO:0035637 91 0.060
renin angiotensin regulation of aldosterone production GO:0002018 3 0.059
regulation of myeloid cell differentiation GO:0045637 96 0.059
negative regulation of phosphorus metabolic process GO:0010563 184 0.058
positive regulation of cellular amine metabolic process GO:0033240 5 0.058
forebrain neuron development GO:0021884 30 0.056
blood vessel morphogenesis GO:0048514 285 0.056
regulation of cysteine type endopeptidase activity GO:2000116 65 0.055
protein processing GO:0016485 163 0.055
regulation of retinal ganglion cell axon guidance GO:0090259 2 0.054
development of primary female sexual characteristics GO:0046545 73 0.054
Human
negative regulation of actin filament polymerization GO:0030837 11 0.054
apoptotic process involved in development GO:1902742 28 0.053
Human
neutrophil chemotaxis GO:0030593 36 0.053
cellular amine metabolic process GO:0044106 44 0.052
granulocyte chemotaxis GO:0071621 39 0.051
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.051
positive chemotaxis GO:0050918 18 0.051
Mouse
regulation of response to wounding GO:1903034 189 0.050
negative regulation of protein modification process GO:0031400 163 0.049
regulation of actin filament based process GO:0032970 99 0.047
cellular homeostasis GO:0019725 240 0.047
Fly
positive regulation of proteolysis GO:0045862 85 0.046
positive regulation of cell growth GO:0030307 33 0.046
negative regulation of nervous system development GO:0051961 156 0.046
Zebrafish
lamellipodium organization GO:0097581 29 0.045
mononuclear cell migration GO:0071674 8 0.045
cytokine production GO:0001816 319 0.045
female sex differentiation GO:0046660 84 0.045
Human
myeloid leukocyte migration GO:0097529 57 0.045
neutrophil migration GO:1990266 37 0.044
negative regulation of cell development GO:0010721 169 0.044
Zebrafish
regulation of protein transport GO:0051223 163 0.043
response to growth factor GO:0070848 198 0.043
heart contraction GO:0060047 93 0.042
negative regulation of epithelial cell proliferation GO:0050680 64 0.041
sprouting angiogenesis GO:0002040 26 0.041
regulation of cytokine production GO:0001817 266 0.041
regulation of epithelial cell proliferation GO:0050678 141 0.040
locomotory behavior GO:0007626 195 0.040
Fly
activation of cysteine type endopeptidase activity GO:0097202 27 0.039
regulation of neutrophil migration GO:1902622 14 0.039
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress GO:1902218 1 0.038
cell migration involved in heart development GO:0060973 8 0.038
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.038
smoothened signaling pathway GO:0007224 105 0.038
inorganic cation transmembrane transport GO:0098662 207 0.037
regulation of organelle organization GO:0033043 289 0.037
negative regulation of cellular component organization GO:0051129 194 0.037
Zebrafish
embryonic organ morphogenesis GO:0048562 276 0.036
regulation of neurotrophin trk receptor signaling pathway GO:0051386 4 0.036
small gtpase mediated signal transduction GO:0007264 97 0.035
regulation of renal output by angiotensin GO:0002019 2 0.035
dna metabolic process GO:0006259 303 0.035
morphogenesis of a branching epithelium GO:0061138 193 0.034
positive regulation of hydrolase activity GO:0051345 148 0.033
cellular response to heparin GO:0071504 1 0.033
cellular component assembly involved in morphogenesis GO:0010927 139 0.033
muscle cell cellular homeostasis GO:0046716 12 0.033
Fly
g protein coupled receptor signaling pathway GO:0007186 243 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.033
negative regulation of intracellular signal transduction GO:1902532 167 0.033
cation transmembrane transport GO:0098655 266 0.031
regulation of organ morphogenesis GO:2000027 144 0.031
oxidation reduction process GO:0055114 342 0.031
locomotion involved in locomotory behavior GO:0031987 8 0.031
Fly
regulation of neutrophil chemotaxis GO:0090022 14 0.031
purine nucleotide metabolic process GO:0006163 302 0.031
regulation of establishment of protein localization GO:0070201 181 0.031
endomembrane system organization GO:0010256 147 0.031
membrane organization GO:0061024 245 0.031
response to organonitrogen compound GO:0010243 246 0.030
inorganic ion transmembrane transport GO:0098660 234 0.030
epithelial cell proliferation GO:0050673 174 0.030
extrinsic apoptotic signaling pathway GO:0097191 126 0.030
morphogenesis of a branching structure GO:0001763 203 0.030
mesoderm formation GO:0001707 62 0.030
cellular ketone metabolic process GO:0042180 84 0.030
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.030
regulation of lymphocyte activation GO:0051249 240 0.030
regulation of peptidase activity GO:0052547 96 0.030
negative regulation of response to wounding GO:1903035 77 0.029
ras protein signal transduction GO:0007265 77 0.029
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902238 1 0.029
sensory organ morphogenesis GO:0090596 242 0.029
organonitrogen compound catabolic process GO:1901565 264 0.029
negative regulation of protein phosphorylation GO:0001933 126 0.029
response to nutrient levels GO:0031667 109 0.029
transmembrane transport GO:0055085 412 0.029
negative regulation of heart rate GO:0010459 4 0.029
cell fate specification GO:0001708 72 0.028
Fly
palate development GO:0060021 76 0.028
response to heparin GO:0071503 1 0.028
t cell proliferation GO:0042098 120 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
negative regulation of epithelial cell migration GO:0010633 9 0.027
cellular response to growth factor stimulus GO:0071363 197 0.027
action potential GO:0001508 78 0.026
positive regulation of organelle organization GO:0010638 128 0.026
t cell activation GO:0042110 289 0.026
peptidyl amino acid modification GO:0018193 336 0.026
regulation of actin cytoskeleton organization GO:0032956 84 0.026
aromatic compound catabolic process GO:0019439 286 0.026
response to molecule of bacterial origin GO:0002237 143 0.026
regulation of granulocyte chemotaxis GO:0071622 17 0.025
cation transport GO:0006812 399 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
regulation of peptidyl serine phosphorylation GO:0033135 39 0.025
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.025
Zebrafish
inflammatory response GO:0006954 244 0.025
mesonephric tubule development GO:0072164 94 0.024
positive regulation of protein transport GO:0051222 93 0.024
regulation of endothelial cell migration GO:0010594 22 0.024
mammary gland epithelial cell proliferation GO:0033598 24 0.024
compound eye development GO:0048749 1 0.024
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1990127 1 0.024
positive regulation of apoptotic signaling pathway GO:2001235 95 0.024
peptidyl serine phosphorylation GO:0018105 74 0.024
regulation of system process GO:0044057 200 0.024
neuron apoptotic process GO:0051402 142 0.024
regulation of smooth muscle cell migration GO:0014910 6 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
regulation of protein localization GO:0032880 231 0.023
circadian rhythm GO:0007623 114 0.023
Fly
organelle assembly GO:0070925 177 0.023
alpha beta t cell activation GO:0046631 91 0.022
endothelial cell migration GO:0043542 44 0.022
maintenance of location GO:0051235 89 0.022
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.022
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.022
negative regulation of synapse assembly GO:0051964 3 0.022
Zebrafish
bmp signaling pathway GO:0030509 93 0.022
metal ion homeostasis GO:0055065 189 0.022
nucleotide metabolic process GO:0009117 332 0.021
negative regulation of apoptotic signaling pathway GO:2001234 104 0.021
positive regulation of endopeptidase activity GO:0010950 43 0.021
glomerulus development GO:0032835 40 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
transmission of nerve impulse GO:0019226 76 0.021
heterocycle catabolic process GO:0046700 280 0.021
circulatory system process GO:0003013 197 0.021
negative regulation of protein complex assembly GO:0031333 25 0.021
regulation of membrane potential GO:0042391 192 0.021
immune effector process GO:0002252 321 0.020
response to lipopolysaccharide GO:0032496 128 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
divalent inorganic cation homeostasis GO:0072507 138 0.020
purine containing compound metabolic process GO:0072521 311 0.020
epidermis development GO:0008544 187 0.020
leukocyte proliferation GO:0070661 172 0.019
neuronal action potential GO:0019228 54 0.019
endocytosis GO:0006897 168 0.019
neural tube closure GO:0001843 90 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
ion transmembrane transport GO:0034220 361 0.019
midgut development GO:0007494 4 0.019
lymphocyte differentiation GO:0030098 242 0.019
regulation of cellular response to stress GO:0080135 159 0.019
leukocyte chemotaxis GO:0030595 69 0.019
response to peptide GO:1901652 136 0.019
positive regulation of cellular component biogenesis GO:0044089 94 0.019
neuron death GO:0070997 154 0.019
rho protein signal transduction GO:0007266 32 0.019
positive regulation of cell activation GO:0050867 158 0.018
regulation of defense response GO:0031347 233 0.018
cation homeostasis GO:0055080 212 0.018
regulation of secretion by cell GO:1903530 249 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
regulation of cellular response to growth factor stimulus GO:0090287 82 0.018
leukocyte activation involved in immune response GO:0002366 126 0.018
primary neural tube formation GO:0014020 95 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902239 1 0.018
positive regulation of vasodilation GO:0045909 3 0.017
positive regulation of peptidase activity GO:0010952 49 0.017
positive regulation of cytokine production GO:0001819 174 0.017
phospholipase c activating angiotensin activated signaling pathway GO:0086097 1 0.017
regulation of homeostatic process GO:0032844 182 0.017
cellular divalent inorganic cation homeostasis GO:0072503 127 0.017
ensheathment of neurons GO:0007272 76 0.017
tube closure GO:0060606 91 0.017
cellular chemical homeostasis GO:0055082 215 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
mapk cascade GO:0000165 281 0.017
negative regulation of smooth muscle cell apoptotic process GO:0034392 1 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
regulation of intracellular transport GO:0032386 159 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress GO:1902219 1 0.017
regulation of cell substrate adhesion GO:0010810 73 0.017
anion transport GO:0006820 177 0.017
nitrogen compound transport GO:0071705 271 0.017
retina homeostasis GO:0001895 23 0.017
microtubule based process GO:0007017 236 0.017
neural tube development GO:0021915 160 0.016
monocyte chemotaxis GO:0002548 5 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
protein polymerization GO:0051258 57 0.016
nephron epithelium development GO:0072009 92 0.016
developmental maturation GO:0021700 193 0.016
divalent metal ion transport GO:0070838 172 0.016
g protein coupled receptor signaling pathway coupled to cgmp nucleotide second messenger GO:0007199 1 0.016
appendage development GO:0048736 166 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.016
regulation of ion transport GO:0043269 215 0.016
multi multicellular organism process GO:0044706 109 0.016
rac protein signal transduction GO:0016601 13 0.016
purine containing compound catabolic process GO:0072523 213 0.016
cognition GO:0050890 149 0.016
muscle tissue development GO:0060537 308 0.016
t cell differentiation GO:0030217 174 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
positive regulation of growth GO:0045927 104 0.016
angiotensin activated signaling pathway GO:0038166 4 0.016
regulation of endocytosis GO:0030100 69 0.016
cell type specific apoptotic process GO:0097285 268 0.016
cytokine secretion GO:0050663 72 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.015
muscle cell differentiation GO:0042692 261 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
cilium assembly GO:0042384 81 0.015
zymogen activation GO:0031638 41 0.015
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.015
regulation of mapk cascade GO:0043408 248 0.015
nucleoside metabolic process GO:0009116 246 0.015
ossification GO:0001503 216 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
regulation of smoothened signaling pathway GO:0008589 58 0.015
response to inorganic substance GO:0010035 96 0.015
negative regulation of lymphocyte activation GO:0051250 91 0.015
wound healing GO:0042060 157 0.015
synapse assembly GO:0007416 56 0.015
Zebrafish
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.015
organophosphate catabolic process GO:0046434 232 0.015
positive regulation of t cell activation GO:0050870 101 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
hemostasis GO:0007599 78 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
covalent chromatin modification GO:0016569 163 0.015
branching involved in ureteric bud morphogenesis GO:0001658 56 0.015
fatty acid metabolic process GO:0006631 121 0.015
sensory perception of sound GO:0007605 97 0.015
kidney morphogenesis GO:0060993 83 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
divalent inorganic cation transport GO:0072511 178 0.014
chromatin organization GO:0006325 206 0.014
tube formation GO:0035148 140 0.014
regulation of body fluid levels GO:0050878 162 0.014
hormone secretion GO:0046879 128 0.014
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.014
cellular response to molecule of bacterial origin GO:0071219 83 0.014
organic anion transport GO:0015711 137 0.014
regulation of transferase activity GO:0051338 263 0.014
cell substrate adhesion GO:0031589 130 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
negative regulation of neuron projection regeneration GO:0070571 3 0.014
cytoplasmic transport GO:0016482 234 0.014
positive regulation of protein complex assembly GO:0031334 45 0.014
striated muscle tissue development GO:0014706 293 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
regulation of hormone levels GO:0010817 211 0.014
negative regulation of defense response GO:0031348 77 0.014
tissue homeostasis GO:0001894 115 0.014
mesonephric tubule morphogenesis GO:0072171 63 0.014
sensory perception of mechanical stimulus GO:0050954 107 0.014
regulation of t cell activation GO:0050863 170 0.014

Robo2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.052
congenital nervous system abnormality DOID:2490 0 0.052
disease of anatomical entity DOID:7 0 0.016
Human
nervous system disease DOID:863 0 0.016