Mus musculus

52 known processes

Rrm1

ribonucleotide reductase M1

(Aliases: RnrM1)

Rrm1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic cell cycle GO:0051321 122 0.882
meiotic nuclear division GO:0007126 115 0.876
microtubule cytoskeleton organization GO:0000226 157 0.825
synapsis GO:0007129 34 0.796
meiotic cell cycle process GO:1903046 77 0.775
meiosis i GO:0007127 60 0.771
organelle fission GO:0048285 170 0.697
cellular response to dna damage stimulus GO:0006974 207 0.640
chromosome organization involved in meiosis GO:0070192 39 0.559
reciprocal dna recombination GO:0035825 16 0.524
recombinational repair GO:0000725 21 0.486
mitotic cell cycle GO:0000278 195 0.460
regulation of cell cycle process GO:0010564 160 0.426
regulation of cell cycle GO:0051726 281 0.422
microtubule based process GO:0007017 236 0.409
double strand break repair GO:0006302 48 0.360
dna metabolic process GO:0006259 303 0.358
mitotic spindle organization GO:0007052 10 0.346
double strand break repair via homologous recombination GO:0000724 21 0.345
protein heterotetramerization GO:0051290 4 0.263
dna unwinding involved in dna replication GO:0006268 5 0.249
dna geometric change GO:0032392 7 0.247
deoxyribonucleotide metabolic process GO:0009262 14 0.236
nucleobase containing small molecule metabolic process GO:0055086 352 0.234
dna duplex unwinding GO:0032508 7 0.215
mitotic cell cycle process GO:1903047 159 0.213
lateral inhibition GO:0046331 1 0.199
dna repair GO:0006281 107 0.196
endocytosis GO:0006897 168 0.192
ribose phosphate metabolic process GO:0019693 291 0.188
protein modification by small protein conjugation or removal GO:0070647 207 0.188
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.175
nuclear dna replication GO:0033260 3 0.149
mitotic nuclear division GO:0007067 48 0.147
nucleotide metabolic process GO:0009117 332 0.143
nuclear division GO:0000280 158 0.142
gonad development GO:0008406 141 0.137
Worm
dna replication GO:0006260 52 0.136
nucleoside phosphate biosynthetic process GO:1901293 79 0.135
regulation of mitotic cell cycle GO:0007346 126 0.129
organic cyclic compound catabolic process GO:1901361 295 0.128
regulation of mitotic cell cycle phase transition GO:1901990 73 0.123
negative regulation of cell cycle GO:0045786 123 0.119
positive regulation of cellular catabolic process GO:0031331 148 0.115
deoxyribonucleotide biosynthetic process GO:0009263 6 0.115
spermatogenesis GO:0007283 284 0.114
ribonucleoside triphosphate catabolic process GO:0009203 199 0.113
dna dependent dna replication GO:0006261 24 0.113
rna dependent dna replication GO:0006278 3 0.111
cofactor metabolic process GO:0051186 80 0.110
chromosome segregation GO:0007059 48 0.109
dna recombination GO:0006310 92 0.102
spindle organization GO:0007051 28 0.101
positive regulation of cell cycle GO:0045787 92 0.101
carbohydrate derivative biosynthetic process GO:1901137 183 0.099
organonitrogen compound catabolic process GO:1901565 264 0.097
oxidation reduction process GO:0055114 342 0.094
germ cell development GO:0007281 185 0.089
purine ribonucleotide metabolic process GO:0009150 290 0.088
inner cell mass cell proliferation GO:0001833 15 0.083
receptor mediated endocytosis GO:0006898 51 0.083
protein dna complex subunit organization GO:0071824 28 0.079
nucleoside phosphate metabolic process GO:0006753 338 0.079
negative regulation of organelle organization GO:0010639 90 0.079
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.078
reciprocal meiotic recombination GO:0007131 16 0.077
male gamete generation GO:0048232 285 0.075
dna conformation change GO:0071103 37 0.075
mitotic sister chromatid segregation GO:0000070 14 0.074
negative regulation of cellular component organization GO:0051129 194 0.073
development of primary sexual characteristics GO:0045137 143 0.071
Worm
negative regulation of cell cycle process GO:0010948 69 0.070
response to oxidative stress GO:0006979 123 0.069
microtubule polymerization or depolymerization GO:0031109 26 0.069
heterocycle catabolic process GO:0046700 280 0.068
ribonucleotide catabolic process GO:0009261 208 0.068
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.068
response to inorganic substance GO:0010035 96 0.068
modification dependent macromolecule catabolic process GO:0043632 133 0.067
gene silencing GO:0016458 38 0.067
regulation of cell division GO:0051302 76 0.065
regulation of spindle organization GO:0090224 2 0.065
purine nucleoside triphosphate metabolic process GO:0009144 226 0.064
intracellular protein transport GO:0006886 204 0.064
telomere maintenance via telomerase GO:0007004 1 0.064
organophosphate biosynthetic process GO:0090407 122 0.064
nucleotide biosynthetic process GO:0009165 78 0.062
nucleoside catabolic process GO:0009164 206 0.057
regulation of microtubule based process GO:0032886 52 0.056
nucleoside phosphate catabolic process GO:1901292 222 0.056
translesion synthesis GO:0019985 1 0.054
purine nucleotide metabolic process GO:0006163 302 0.051
nucleocytoplasmic transport GO:0006913 139 0.050
purine nucleotide catabolic process GO:0006195 211 0.050
regulation of cellular protein catabolic process GO:1903362 61 0.050
chromatin silencing GO:0006342 15 0.049
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.049
purine nucleoside triphosphate catabolic process GO:0009146 203 0.049
female meiotic division GO:0007143 21 0.047
protein localization to organelle GO:0033365 185 0.047
aromatic compound catabolic process GO:0019439 286 0.046
regulation of cellular catabolic process GO:0031329 242 0.046
purine ribonucleoside metabolic process GO:0046128 241 0.045
apoptotic signaling pathway GO:0097190 306 0.045
regulation of mitosis GO:0007088 29 0.045
regulation of transcription by chromatin organization GO:0034401 0 0.043
dna damage checkpoint GO:0000077 26 0.043
negative regulation of gene expression epigenetic GO:0045814 15 0.043
ubiquitin dependent protein catabolic process GO:0006511 129 0.042
nucleotide catabolic process GO:0009166 217 0.042
ribonucleoside triphosphate metabolic process GO:0009199 220 0.041
ribonucleoside metabolic process GO:0009119 245 0.041
negative regulation of chromatin silencing GO:0031936 1 0.041
purine nucleoside catabolic process GO:0006152 205 0.041
organelle assembly GO:0070925 177 0.040
blastocyst development GO:0001824 80 0.040
regulation of cellular response to stress GO:0080135 159 0.040
intracellular mrna localization GO:0008298 4 0.037
organophosphate catabolic process GO:0046434 232 0.037
protein maturation GO:0051604 176 0.037
regulation of meiotic cell cycle GO:0051445 34 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
blastocyst growth GO:0001832 23 0.036
regulation of organelle organization GO:0033043 289 0.036
nucleotide excision repair GO:0006289 13 0.036
nucleoside monophosphate metabolic process GO:0009123 85 0.035
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.035
regulation of nuclear division GO:0051783 56 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.035
chromatin organization GO:0006325 206 0.034
cellular amino acid metabolic process GO:0006520 103 0.034
engulfment of apoptotic cell GO:0043652 3 0.034
regulation of protein catabolic process GO:0042176 108 0.034
regulation of hydrolase activity GO:0051336 246 0.033
negative regulation of mitotic cell cycle GO:0045930 58 0.033
macromolecule catabolic process GO:0009057 281 0.033
response to radiation GO:0009314 165 0.032
protein ubiquitination GO:0016567 171 0.032
female gamete generation GO:0007292 74 0.032
cellular protein complex assembly GO:0043623 116 0.031
response to organic cyclic compound GO:0014070 198 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
response to ionizing radiation GO:0010212 42 0.031
regulation of microtubule cytoskeleton organization GO:0070507 37 0.031
synaptonemal complex assembly GO:0007130 13 0.030
microtubule organizing center organization GO:0031023 28 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.029
regulation of cytoskeleton organization GO:0051493 122 0.029
microtubule nucleation GO:0007020 2 0.029
regulation of ras gtpase activity GO:0032318 88 0.028
genitalia development GO:0048806 37 0.028
Worm
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.028
dna endoreduplication GO:0042023 4 0.028
cell type specific apoptotic process GO:0097285 268 0.027
maintenance of location GO:0051235 89 0.027
purine containing compound catabolic process GO:0072523 213 0.027
cellular ketone metabolic process GO:0042180 84 0.026
mitotic recombination GO:0006312 3 0.026
intra s dna damage checkpoint GO:0031573 4 0.026
purine ribonucleotide catabolic process GO:0009154 208 0.026
regulation of transferase activity GO:0051338 263 0.025
mitotic centrosome separation GO:0007100 4 0.025
nuclear envelope organization GO:0006998 11 0.025
regulation of chromatin silencing GO:0031935 2 0.025
purine containing compound metabolic process GO:0072521 311 0.025
carbohydrate derivative catabolic process GO:1901136 231 0.025
ras protein signal transduction GO:0007265 77 0.025
homeostasis of number of cells GO:0048872 210 0.024
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
cofactor biosynthetic process GO:0051188 41 0.023
cytoplasmic transport GO:0016482 234 0.023
peptidyl amino acid modification GO:0018193 336 0.023
microtubule based movement GO:0007018 84 0.023
regulation of circadian rhythm GO:0042752 58 0.023
chromosome separation GO:0051304 14 0.022
anatomical structure homeostasis GO:0060249 145 0.022
non recombinational repair GO:0000726 10 0.022
atp catabolic process GO:0006200 55 0.022
cellular response to lipid GO:0071396 145 0.022
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.022
protein heterooligomerization GO:0051291 14 0.022
cellular response to hormone stimulus GO:0032870 150 0.021
ribonucleoside monophosphate metabolic process GO:0009161 80 0.021
double strand break repair via nonhomologous end joining GO:0006303 10 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
protein localization to nucleus GO:0034504 121 0.021
dendrite development GO:0016358 115 0.020
meiotic chromosome condensation GO:0010032 3 0.020
negative regulation of gene silencing GO:0060969 2 0.020
cell fate commitment GO:0045165 210 0.020
regulation of gtp catabolic process GO:0033124 113 0.020
neural precursor cell proliferation GO:0061351 121 0.020
response to steroid hormone GO:0048545 56 0.020
membrane organization GO:0061024 245 0.020
response to lipopolysaccharide GO:0032496 128 0.019
response to uv GO:0009411 44 0.019
nuclear import GO:0051170 95 0.019
cellular amine metabolic process GO:0044106 44 0.019
amine metabolic process GO:0009308 45 0.019
nucleus organization GO:0006997 45 0.019
protein catabolic process GO:0030163 221 0.019
protein polymerization GO:0051258 57 0.019
positive regulation of organelle organization GO:0010638 128 0.019
methylation GO:0032259 134 0.019
cellular lipid metabolic process GO:0044255 323 0.019
positive regulation of hydrolase activity GO:0051345 148 0.018
regulation of cytoplasmic transport GO:1903649 112 0.018
nucleoside monophosphate catabolic process GO:0009125 59 0.018
positive regulation of nfat protein import into nucleus GO:0051533 1 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
protein targeting GO:0006605 143 0.018
ovulation GO:0030728 15 0.018
protein modification by small protein conjugation GO:0032446 187 0.017
establishment of protein localization to organelle GO:0072594 118 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
negative regulation of proteolysis GO:0045861 74 0.017
negative regulation of cellular protein catabolic process GO:1903363 22 0.017
leukocyte proliferation GO:0070661 172 0.017
cellular response to oxidative stress GO:0034599 76 0.017
regulation of protein localization GO:0032880 231 0.017
sister chromatid cohesion GO:0007062 12 0.017
response to light stimulus GO:0009416 135 0.017
asymmetric stem cell division GO:0098722 3 0.017
mitotic cell cycle checkpoint GO:0007093 31 0.016
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.016
regulation of interleukin 1 alpha secretion GO:0050705 3 0.016
telomere maintenance GO:0000723 19 0.016
regulation of double strand break repair via nonhomologous end joining GO:2001032 2 0.016
cellular response to radiation GO:0071478 28 0.016
response to oxygen levels GO:0070482 62 0.016
positive regulation of protein modification process GO:0031401 299 0.016
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 9 0.016
spindle assembly involved in female meiosis GO:0007056 3 0.016
protein methylation GO:0006479 81 0.016
negative regulation of protein maturation GO:1903318 79 0.016
protein import into nucleus GO:0006606 95 0.016
protein complex disassembly GO:0043241 40 0.016
mitotic cytokinesis GO:0000281 4 0.015
regulation of double strand break repair via homologous recombination GO:0010569 2 0.015
regulation of dna dependent dna replication GO:0090329 8 0.015
dna integrity checkpoint GO:0031570 28 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
sister chromatid segregation GO:0000819 20 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
lipid biosynthetic process GO:0008610 179 0.015
regulation of intracellular transport GO:0032386 159 0.015
regulation of mitotic sister chromatid segregation GO:0033047 12 0.014
regulation of protein transport GO:0051223 163 0.014
negative regulation of meiotic cell cycle GO:0051447 14 0.014
mitotic g1 dna damage checkpoint GO:0031571 4 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
positive regulation of intracellular transport GO:0032388 70 0.014
regulation of intracellular protein transport GO:0033157 82 0.014
response to acid chemical GO:0001101 111 0.014
regulation of cell cycle phase transition GO:1901987 77 0.014
centrosome organization GO:0051297 26 0.014
protein processing GO:0016485 163 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
negative regulation of nuclear division GO:0051784 19 0.013
response to organonitrogen compound GO:0010243 246 0.013
hatching GO:0035188 4 0.013
establishment or maintenance of cell polarity GO:0007163 86 0.013
regulation of cell activation GO:0050865 289 0.013
meiotic chromosome segregation GO:0045132 19 0.013
nucleic acid transport GO:0050657 18 0.013
positive regulation of protein catabolic process GO:0045732 60 0.013
regulation of kinase activity GO:0043549 249 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
regulation of chromosome segregation GO:0051983 21 0.013
organism emergence from protective structure GO:0071684 4 0.013
regulation of meiosis i GO:0060631 7 0.013
negative regulation of cell division GO:0051782 24 0.013
regulation of interleukin 1 alpha production GO:0032650 4 0.013
camera type eye development GO:0043010 266 0.013
negative regulation of immune system process GO:0002683 209 0.013
microtubule polymerization GO:0046785 12 0.012
protein desumoylation GO:0016926 2 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
negative regulation of cell cycle phase transition GO:1901988 48 0.012
positive regulation of chromosome organization GO:2001252 33 0.012
male meiosis GO:0007140 37 0.012
neuron death GO:0070997 154 0.012
dna replication initiation GO:0006270 5 0.012
oogenesis GO:0048477 56 0.012
striated muscle myosin thick filament assembly GO:0071688 1 0.012
telomere maintenance via telomere lengthening GO:0010833 4 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
developmental maturation GO:0021700 193 0.012
nucleoside metabolic process GO:0009116 246 0.012
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.012
dna replication independent nucleosome assembly GO:0006336 1 0.012
response to reactive oxygen species GO:0000302 56 0.011
positive regulation of gtpase activity GO:0043547 85 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
stem cell differentiation GO:0048863 268 0.011
lymphocyte proliferation GO:0046651 164 0.011
protein import GO:0017038 101 0.011
synaptonemal complex organization GO:0070193 15 0.011
covalent chromatin modification GO:0016569 163 0.011
fertilization GO:0009566 127 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
neuron apoptotic process GO:0051402 142 0.011
coenzyme metabolic process GO:0006732 52 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
adult behavior GO:0030534 135 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
response to temperature stimulus GO:0009266 55 0.011
positive regulation of nervous system development GO:0051962 221 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.011
regulation of centriole replication GO:0046599 1 0.011
spindle assembly involved in mitosis GO:0090307 4 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
regulation of cellular amine metabolic process GO:0033238 20 0.011
carbohydrate metabolic process GO:0005975 230 0.011
dna ligation GO:0006266 3 0.010
molting cycle GO:0042303 90 0.010
mismatch repair GO:0006298 8 0.010
body morphogenesis GO:0010171 45 0.010
negative regulation of cell development GO:0010721 169 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
nitrogen compound transport GO:0071705 271 0.010
axonogenesis GO:0007409 274 0.010

Rrm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
organ system cancer DOID:0050686 0 0.012