Mus musculus

0 known processes

Rusc1

RUN and SH3 domain containing 1

(Aliases: 2210403N08Rik,AA408288,NESCA)

Rusc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic vesicle docking involved in exocytosis GO:0016081 4 0.260
ion transmembrane transport GO:0034220 361 0.197
regulation of synaptic vesicle priming GO:0010807 4 0.172
cation transmembrane transport GO:0098655 266 0.146
synaptic vesicle fusion to presynaptic membrane GO:0031629 3 0.141
regulation of ion transport GO:0043269 215 0.125
synaptic vesicle priming GO:0016082 8 0.121
membrane organization GO:0061024 245 0.111
synaptic vesicle transport GO:0048489 57 0.104
synaptic vesicle localization GO:0097479 59 0.094
vesicle docking involved in exocytosis GO:0006904 7 0.094
axonogenesis GO:0007409 274 0.091
regulation of vesicle mediated transport GO:0060627 139 0.077
inorganic cation transmembrane transport GO:0098662 207 0.075
regulation of membrane potential GO:0042391 192 0.069
positive regulation of cell death GO:0010942 224 0.068
vesicle localization GO:0051648 86 0.065
cation transport GO:0006812 399 0.062
regulation of synaptic vesicle exocytosis GO:2000300 11 0.061
regulation of synaptic vesicle transport GO:1902803 13 0.060
ras protein signal transduction GO:0007265 77 0.059
vesicle organization GO:0016050 60 0.059
establishment of synaptic vesicle localization GO:0097480 57 0.059
cellular amino acid metabolic process GO:0006520 103 0.057
cellular metal ion homeostasis GO:0006875 151 0.057
sodium ion transmembrane transport GO:0035725 49 0.054
amine metabolic process GO:0009308 45 0.052
blood circulation GO:0008015 195 0.052
regionalization GO:0003002 337 0.052
transmembrane transport GO:0055085 412 0.052
establishment of vesicle localization GO:0051650 81 0.050
anion transport GO:0006820 177 0.050
intracellular mrna localization GO:0008298 4 0.048
nucleobase containing small molecule metabolic process GO:0055086 352 0.048
regulation of secretion by cell GO:1903530 249 0.047
organelle localization GO:0051640 179 0.047
nitrogen compound transport GO:0071705 271 0.047
protein ubiquitination GO:0016567 171 0.046
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.045
cellular chemical homeostasis GO:0055082 215 0.045
carbohydrate derivative catabolic process GO:1901136 231 0.044
vesicle docking GO:0048278 7 0.044
cellular ketone metabolic process GO:0042180 84 0.044
axon cargo transport GO:0008088 33 0.044
positive regulation of protein modification process GO:0031401 299 0.044
endocytosis GO:0006897 168 0.044
vesicle fusion GO:0006906 16 0.044
regulation of cellular ketone metabolic process GO:0010565 66 0.044
establishment of organelle localization GO:0051656 122 0.044
developmental maturation GO:0021700 193 0.044
purine nucleoside triphosphate catabolic process GO:0009146 203 0.044
regulation of nucleoside metabolic process GO:0009118 130 0.043
neurotransmitter secretion GO:0007269 62 0.041
cation homeostasis GO:0055080 212 0.041
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
regulation of neuron differentiation GO:0045664 281 0.040
cellular lipid metabolic process GO:0044255 323 0.039
microtubule based process GO:0007017 236 0.038
regulation of secretion GO:0051046 274 0.038
protein modification by small protein conjugation or removal GO:0070647 207 0.038
Human
muscle tissue development GO:0060537 308 0.038
cellular homeostasis GO:0019725 240 0.038
purine nucleotide metabolic process GO:0006163 302 0.037
cellular response to peptide GO:1901653 92 0.037
positive regulation of secretion by cell GO:1903532 114 0.037
regulation of feeding behavior GO:0060259 3 0.037
organelle fusion GO:0048284 28 0.037
inorganic ion transmembrane transport GO:0098660 234 0.037
nucleoside metabolic process GO:0009116 246 0.037
cellular amine metabolic process GO:0044106 44 0.036
defecation GO:0030421 1 0.036
nucleoside triphosphate catabolic process GO:0009143 205 0.035
ribonucleotide catabolic process GO:0009261 208 0.035
ribonucleoside metabolic process GO:0009119 245 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.034
divalent inorganic cation homeostasis GO:0072507 138 0.034
protein catabolic process GO:0030163 221 0.034
macromolecule catabolic process GO:0009057 281 0.032
mitochondrion organization GO:0007005 134 0.032
membrane fusion GO:0061025 38 0.032
mitotic cytokinesis GO:0000281 4 0.032
cellular nitrogen compound catabolic process GO:0044270 280 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
microtubule cytoskeleton organization GO:0000226 157 0.031
regulation of neurotransmitter secretion GO:0046928 29 0.031
heterocycle catabolic process GO:0046700 280 0.031
organelle disassembly GO:1903008 2 0.031
organic anion transport GO:0015711 137 0.031
cellular protein complex assembly GO:0043623 116 0.031
response to radiation GO:0009314 165 0.030
glycoprotein biosynthetic process GO:0009101 89 0.030
engulfment of apoptotic cell GO:0043652 3 0.030
regulation of metal ion transport GO:0010959 106 0.029
cell division GO:0051301 120 0.029
exocytosis GO:0006887 121 0.029
microtubule based movement GO:0007018 84 0.029
protein modification by small protein conjugation GO:0032446 187 0.028
Human
positive regulation of necrotic cell death GO:0010940 1 0.028
purine containing compound metabolic process GO:0072521 311 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
aromatic compound catabolic process GO:0019439 286 0.028
cell type specific apoptotic process GO:0097285 268 0.027
muscle cell differentiation GO:0042692 261 0.027
chemotaxis GO:0006935 247 0.026
oocyte anterior posterior axis specification GO:0007314 2 0.026
intracellular protein transport GO:0006886 204 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
detection of abiotic stimulus GO:0009582 60 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
lateral line system development GO:0048925 1 0.026
cellular response to hormone stimulus GO:0032870 150 0.026
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.026
amide transport GO:0042886 138 0.026
sulfur compound metabolic process GO:0006790 100 0.026
response to peptide GO:1901652 136 0.026
regulation of establishment of protein localization GO:0070201 181 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
insulin receptor signaling pathway GO:0008286 49 0.025
maternal determination of anterior posterior axis embryo GO:0008358 2 0.025
response to insulin GO:0032868 100 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
mitotic cell cycle GO:0000278 195 0.025
cell growth GO:0016049 130 0.025
ribose phosphate metabolic process GO:0019693 291 0.024
fertilization GO:0009566 127 0.024
rho protein signal transduction GO:0007266 32 0.024
positive regulation of secretion GO:0051047 130 0.024
asymmetric neuroblast division GO:0055059 1 0.024
positive regulation of cell development GO:0010720 237 0.024
cellular response to insulin stimulus GO:0032869 78 0.024
nuclear division GO:0000280 158 0.023
endomembrane system organization GO:0010256 147 0.023
actin cytoskeleton organization GO:0030036 220 0.023
multicellular organism growth GO:0035264 161 0.023
regulation of intracellular transport GO:0032386 159 0.023
positive regulation of exocytosis GO:0045921 20 0.023
regulation of defense response GO:0031347 233 0.023
oocyte construction GO:0007308 2 0.023
negative regulation of neuron death GO:1901215 98 0.023
cellular response to organonitrogen compound GO:0071417 145 0.023
regulation of cell activation GO:0050865 289 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.023
regulation of neuron projection development GO:0010975 169 0.023
skeletal system development GO:0001501 356 0.023
nucleotide catabolic process GO:0009166 217 0.023
mapk cascade GO:0000165 281 0.023
response to light stimulus GO:0009416 135 0.022
striated muscle tissue development GO:0014706 293 0.022
ribonucleoprotein complex disassembly GO:0032988 3 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.022
regulation of lymphocyte activation GO:0051249 240 0.022
peptide secretion GO:0002790 114 0.022
regulation of organelle organization GO:0033043 289 0.022
respiratory tube development GO:0030323 167 0.022
regulation of neurotransmitter transport GO:0051588 35 0.022
camera type eye development GO:0043010 266 0.022
regulation of cell cycle GO:0051726 281 0.022
detection of stimulus GO:0051606 84 0.022
regulation of kinase activity GO:0043549 249 0.021
divalent inorganic cation transport GO:0072511 178 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
developmental cell growth GO:0048588 84 0.021
epidermis development GO:0008544 187 0.021
carboxylic acid transport GO:0046942 100 0.021
innate immune response GO:0045087 157 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
lipid biosynthetic process GO:0008610 179 0.021
extracellular matrix organization GO:0030198 147 0.021
glycoprotein metabolic process GO:0009100 116 0.020
phospholipid metabolic process GO:0006644 87 0.020
synaptic vesicle exocytosis GO:0016079 26 0.020
nucleoside catabolic process GO:0009164 206 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
lipid modification GO:0030258 65 0.020
negative regulation of immune system process GO:0002683 209 0.020
neurotransmitter transport GO:0006836 76 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
lung development GO:0030324 164 0.020
peptidyl amino acid modification GO:0018193 336 0.019
mitotic cell cycle process GO:1903047 159 0.019
axon guidance GO:0007411 141 0.019
positive regulation of ion transport GO:0043270 65 0.019
regulation of protein localization GO:0032880 231 0.019
organelle fission GO:0048285 170 0.019
sensory perception GO:0007600 245 0.019
regulation of cell motility GO:2000145 236 0.019
calcium ion dependent exocytosis GO:0017156 35 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
positive regulation of neuron differentiation GO:0045666 141 0.018
response to organonitrogen compound GO:0010243 246 0.018
pole plasm assembly GO:0007315 2 0.018
notch signaling pathway GO:0007219 71 0.018
compound eye development GO:0048749 1 0.018
neuron projection guidance GO:0097485 141 0.018
cell maturation GO:0048469 127 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
establishment of protein localization to membrane GO:0090150 54 0.018
positive regulation of membrane potential GO:0045838 15 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
nucleotide metabolic process GO:0009117 332 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
retina development in camera type eye GO:0060041 119 0.018
regulation of vesicle fusion GO:0031338 6 0.018
cartilage development GO:0051216 140 0.018
sensory system development GO:0048880 3 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
muscle system process GO:0003012 141 0.017
cellular calcium ion homeostasis GO:0006874 119 0.017
negative regulation of organelle organization GO:0010639 90 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
purine nucleoside monophosphate metabolic process GO:0009126 81 0.017
chromatin modification GO:0016568 187 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
metal ion homeostasis GO:0055065 189 0.017
regulation of embryonic development GO:0045995 71 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
organic acid transport GO:0015849 101 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
snare complex assembly GO:0035493 6 0.017
sulfur compound biosynthetic process GO:0044272 37 0.016
plasma membrane organization GO:0007009 90 0.016
cellular protein catabolic process GO:0044257 155 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
neural tube development GO:0021915 160 0.016
microtubule based transport GO:0010970 50 0.016
calcium ion homeostasis GO:0055074 127 0.016
organophosphate catabolic process GO:0046434 232 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
guanosine containing compound catabolic process GO:1901069 144 0.016
positive regulation of cell activation GO:0050867 158 0.016
regulation of postsynaptic membrane potential GO:0060078 48 0.016
cellular ion homeostasis GO:0006873 165 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
synaptic transmission GO:0007268 329 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
intracellular receptor signaling pathway GO:0030522 74 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
oxidation reduction process GO:0055114 342 0.016
detection of external stimulus GO:0009581 61 0.016
connective tissue development GO:0061448 179 0.016
lipid localization GO:0010876 126 0.016
meiotic cell cycle GO:0051321 122 0.016
regulation of transferase activity GO:0051338 263 0.015
oocyte axis specification GO:0007309 2 0.015
apoptotic signaling pathway GO:0097190 306 0.015
meiotic nuclear division GO:0007126 115 0.015
positive regulation of neurotransmitter transport GO:0051590 9 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
production of molecular mediator of immune response GO:0002440 103 0.015
fat cell differentiation GO:0045444 160 0.015
myeloid cell differentiation GO:0030099 233 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
skin development GO:0043588 220 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
respiratory system development GO:0060541 190 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
regulation of peptide transport GO:0090087 91 0.015
maintenance of location GO:0051235 89 0.015
bone development GO:0060348 120 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
aminoglycan metabolic process GO:0006022 34 0.014
adult locomotory behavior GO:0008344 91 0.014
leukocyte proliferation GO:0070661 172 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
regulation of t cell activation GO:0050863 170 0.014
segmentation GO:0035282 93 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
cardiac muscle cell contraction GO:0086003 7 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
regulation of reproductive process GO:2000241 66 0.014
carbohydrate metabolic process GO:0005975 230 0.014
transition metal ion transport GO:0000041 38 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
maintenance of presynaptic active zone structure GO:0048790 1 0.014
proteoglycan metabolic process GO:0006029 38 0.014
skeletal muscle organ development GO:0060538 163 0.014
divalent metal ion transport GO:0070838 172 0.014
stress granule disassembly GO:0035617 2 0.014
ribonucleoside monophosphate catabolic process GO:0009158 57 0.014
single fertilization GO:0007338 82 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
response to lipopolysaccharide GO:0032496 128 0.014
sequestering of metal ion GO:0051238 19 0.014
leukocyte differentiation GO:0002521 342 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
positive regulation of programmed cell death GO:0043068 218 0.013
response to extracellular stimulus GO:0009991 127 0.013
protein localization to plasma membrane GO:0072659 57 0.013
membrane depolarization GO:0051899 64 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
negative regulation of nervous system development GO:0051961 156 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
protein localization to membrane GO:0072657 108 0.013
regulation of cell projection organization GO:0031344 206 0.013
organic hydroxy compound transport GO:0015850 93 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
leukocyte migration GO:0050900 124 0.013
regulation of myeloid cell differentiation GO:0045637 96 0.013
regulation of cytokine production GO:0001817 266 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
positive regulation of notch signaling pathway GO:0045747 18 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
regulation of exocytosis GO:0017157 61 0.012
negative regulation of molecular function GO:0044092 258 0.012
lateral inhibition GO:0046331 1 0.012
protein palmitoylation GO:0018345 14 0.012
cholesterol metabolic process GO:0008203 56 0.012
synaptic vesicle recycling GO:0036465 19 0.012
cellular response to lipid GO:0071396 145 0.012
hormone secretion GO:0046879 128 0.012
retrograde transport endosome to golgi GO:0042147 2 0.012
asymmetric stem cell division GO:0098722 3 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
response to inorganic substance GO:0010035 96 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
rab protein signal transduction GO:0032482 1 0.012
response to peptide hormone GO:0043434 127 0.012
monosaccharide transport GO:0015749 58 0.012
cellular response to acid chemical GO:0071229 68 0.012
oocyte development GO:0048599 33 0.012
purine containing compound biosynthetic process GO:0072522 70 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
golgi vesicle transport GO:0048193 30 0.012
peptide transport GO:0015833 133 0.012
response to acid chemical GO:0001101 111 0.012
cardiac muscle tissue development GO:0048738 130 0.012
regulation of transporter activity GO:0032409 57 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
cell chemotaxis GO:0060326 81 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
myotube differentiation GO:0014902 105 0.012
skeletal system morphogenesis GO:0048705 203 0.012
germ cell development GO:0007281 185 0.012
neuron neuron synaptic transmission GO:0007270 69 0.012
lipid transport GO:0006869 98 0.012
regulation of chromosome organization GO:0033044 83 0.011
carbohydrate transport GO:0008643 62 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
peptidyl serine phosphorylation GO:0018105 74 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
monosaccharide metabolic process GO:0005996 106 0.011
positive regulation of transferase activity GO:0051347 167 0.011
homeostasis of number of cells GO:0048872 210 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
response to nutrient levels GO:0031667 109 0.011
negative regulation of mapk cascade GO:0043409 65 0.011
cytoplasmic transport GO:0016482 234 0.011
establishment of protein localization to plasma membrane GO:0090002 34 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
regulation of glutamate secretion GO:0014048 3 0.011
regulation of cell migration GO:0030334 219 0.011
sensory organ morphogenesis GO:0090596 242 0.011
protein localization to organelle GO:0033365 185 0.011
regulation of protein binding GO:0043393 60 0.011
glycerolipid biosynthetic process GO:0045017 50 0.011
steroid metabolic process GO:0008202 119 0.011
glucose homeostasis GO:0042593 128 0.011
cytoskeleton dependent intracellular transport GO:0030705 50 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
membrane tubulation GO:0097320 4 0.011
anatomical structure homeostasis GO:0060249 145 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
cellular response to monosaccharide stimulus GO:0071326 47 0.011
sodium ion transport GO:0006814 73 0.011
cellular glucose homeostasis GO:0001678 52 0.011
peptide hormone secretion GO:0030072 109 0.011
positive regulation of atpase activity GO:0032781 3 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
limb morphogenesis GO:0035108 149 0.010
negative regulation of protein metabolic process GO:0051248 282 0.010
calcium ion transport GO:0006816 159 0.010
regulation of anion transport GO:0044070 27 0.010
muscle cell development GO:0055001 133 0.010
adherens junction maintenance GO:0034334 1 0.010
defense response to other organism GO:0098542 197 0.010
atp metabolic process GO:0046034 75 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.010
t cell differentiation GO:0030217 174 0.010

Rusc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
central nervous system disease DOID:331 0 0.020
neurodegenerative disease DOID:1289 0 0.020
disease of metabolism DOID:0014667 0 0.019
neuromuscular disease DOID:440 0 0.013
neuropathy DOID:870 0 0.013