Mus musculus

133 known processes

Ryr1

ryanodine receptor 1, skeletal muscle

(Aliases: skrr,Ryr,AI528790)

Ryr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle cell differentiation GO:0042692 261 0.791
synaptic transmission GO:0007268 329 0.756
regulation of transmembrane transport GO:0034762 128 0.700
regulation of neuron differentiation GO:0045664 281 0.677
skeletal system development GO:0001501 356 0.664
urinary bladder smooth muscle contraction GO:0014832 5 0.660
neuromuscular synaptic transmission GO:0007274 16 0.657
regulation of ion transmembrane transport GO:0034765 119 0.631
metal ion homeostasis GO:0055065 189 0.592
regulation of ion transport GO:0043269 215 0.555
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.550
inorganic ion transmembrane transport GO:0098660 234 0.535
regulation of muscle system process GO:0090257 80 0.529
Mouse
skeletal muscle adaptation GO:0043501 16 0.529
acetylcholine secretion neurotransmission GO:0014055 2 0.500
muscle cell development GO:0055001 133 0.489
cellular potassium ion transport GO:0071804 43 0.487
calcium ion transport GO:0006816 159 0.485
urinary tract smooth muscle contraction GO:0014848 6 0.479
regulation of vesicle mediated transport GO:0060627 139 0.438
cellular modified amino acid metabolic process GO:0006575 63 0.425
muscle tissue development GO:0060537 308 0.423
positive regulation of cell death GO:0010942 224 0.417
Worm
regulation of feeding behavior GO:0060259 3 0.416
skeletal muscle organ development GO:0060538 163 0.404
calcium ion transmembrane transport GO:0070588 85 0.403
cation homeostasis GO:0055080 212 0.394
striated muscle adaptation GO:0014888 26 0.391
cellular chemical homeostasis GO:0055082 215 0.379
skeletal muscle fiber development GO:0048741 58 0.378
sperm motility GO:0030317 47 0.374
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.363
cellular amino acid metabolic process GO:0006520 103 0.355
membrane depolarization during sa node cell action potential GO:0086046 2 0.354
organic acid transport GO:0015849 101 0.353
sa node cell action potential GO:0086015 4 0.342
acetylcholine transport GO:0015870 2 0.340
muscle system process GO:0003012 141 0.335
transition between fast and slow fiber GO:0014883 9 0.335
neuron apoptotic process GO:0051402 142 0.328
hindbrain maturation GO:0021578 6 0.323
determination of left right asymmetry in nervous system GO:0035545 1 0.320
cation transport GO:0006812 399 0.310
calcium ion homeostasis GO:0055074 127 0.309
vestibular nucleus development GO:0021750 2 0.305
regulation of membrane potential GO:0042391 192 0.303
Mouse
striated muscle cell development GO:0055002 125 0.297
transmembrane transport GO:0055085 412 0.295
central nervous system maturation GO:0021626 6 0.294
renal system process GO:0003014 48 0.293
regulation of neurotransmitter levels GO:0001505 87 0.292
nucleobase containing small molecule metabolic process GO:0055086 352 0.289
cognition GO:0050890 149 0.283
smooth muscle contraction involved in micturition GO:0060083 3 0.281
adult behavior GO:0030534 135 0.279
regulation of skeletal muscle adaptation GO:0014733 12 0.279
cytosolic calcium ion homeostasis GO:0051480 70 0.273
regulation of neuron death GO:1901214 134 0.269
organic hydroxy compound metabolic process GO:1901615 203 0.269
neuron death GO:0070997 154 0.262
cellular divalent inorganic cation homeostasis GO:0072503 127 0.259
locomotory behavior GO:0007626 195 0.259
Zebrafish
muscle adaptation GO:0043500 39 0.257
regulation of neuron apoptotic process GO:0043523 122 0.241
skeletal myofibril assembly GO:0014866 4 0.241
myotube cell development GO:0014904 60 0.240
axonogenesis GO:0007409 274 0.238
cerebellum development GO:0021549 77 0.237
regulation of cell projection organization GO:0031344 206 0.233
spinal cord motor neuron differentiation GO:0021522 35 0.224
learning or memory GO:0007611 148 0.221
learning GO:0007612 98 0.215
blood circulation GO:0008015 195 0.215
Mouse Fly
muscle contraction GO:0006936 101 0.212
neural nucleus development GO:0048857 22 0.211
regulation of neuron projection development GO:0010975 169 0.211
negative regulation of neuron death GO:1901215 98 0.210
amino acid transport GO:0006865 61 0.210
nucleoside phosphate metabolic process GO:0006753 338 0.204
striated muscle contraction GO:0006941 45 0.203
Zebrafish Mouse
cation transmembrane transport GO:0098655 266 0.202
adult locomotory behavior GO:0008344 91 0.202
metencephalon development GO:0022037 89 0.200
cell type specific apoptotic process GO:0097285 268 0.198
Mouse
myotube differentiation GO:0014902 105 0.193
adult walking behavior GO:0007628 41 0.191
pons development GO:0021548 13 0.190
negative regulation of neuron apoptotic process GO:0043524 92 0.190
glial cell differentiation GO:0010001 131 0.189
negative regulation of hormone biosynthetic process GO:0032353 4 0.187
cellular component assembly involved in morphogenesis GO:0010927 139 0.186
visual behavior GO:0007632 45 0.186
regulation of nucleotide metabolic process GO:0006140 169 0.184
regulation of system process GO:0044057 200 0.184
Mouse
cerebellar purkinje cell layer development GO:0021680 26 0.182
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.181
carbohydrate metabolic process GO:0005975 230 0.181
divalent metal ion transport GO:0070838 172 0.177
inorganic cation transmembrane transport GO:0098662 207 0.177
connective tissue development GO:0061448 179 0.176
organic anion transport GO:0015711 137 0.175
determination of left right symmetry GO:0007368 80 0.174
regulation of potassium ion transmembrane transporter activity GO:1901016 7 0.173
anion transport GO:0006820 177 0.171
potassium ion transport GO:0006813 52 0.171
monocarboxylic acid metabolic process GO:0032787 191 0.169
smooth muscle contraction GO:0006939 44 0.168
negative regulation of hormone metabolic process GO:0032351 4 0.167
regulation of metal ion transport GO:0010959 106 0.166
Mouse
extraocular skeletal muscle development GO:0002074 2 0.165
organelle assembly GO:0070925 177 0.165
actin cytoskeleton organization GO:0030036 220 0.164
striated muscle tissue development GO:0014706 293 0.164
sensory organ morphogenesis GO:0090596 242 0.163
central nervous system neuron differentiation GO:0021953 162 0.163
acetate ester transport GO:1901374 2 0.162
neurotransmitter transport GO:0006836 76 0.159
regulation of cellular catabolic process GO:0031329 242 0.156
endomembrane system organization GO:0010256 147 0.155
tube formation GO:0035148 140 0.155
multicellular organismal response to stress GO:0033555 62 0.152
associative learning GO:0008306 61 0.151
developmental maturation GO:0021700 193 0.150
axon guidance GO:0007411 141 0.148
ribose phosphate metabolic process GO:0019693 291 0.145
regulation of homeostatic process GO:0032844 182 0.144
regulation of potassium ion transport GO:0043266 16 0.143
organelle fission GO:0048285 170 0.138
visual learning GO:0008542 44 0.137
ribonucleoside triphosphate catabolic process GO:0009203 199 0.137
wnt signaling pathway GO:0016055 188 0.136
Mouse
cerebellar cortex formation GO:0021697 22 0.136
cerebellar purkinje cell differentiation GO:0021702 13 0.135
excretion GO:0007588 22 0.135
myosin filament assembly GO:0031034 2 0.133
carboxylic acid transport GO:0046942 100 0.132
dendrite development GO:0016358 115 0.131
cerebellar cortex development GO:0021695 48 0.130
axonal fasciculation GO:0007413 15 0.128
mitochondrion organization GO:0007005 134 0.127
cartilage development GO:0051216 140 0.126
regulation of muscle adaptation GO:0043502 31 0.126
cerebellum morphogenesis GO:0021587 42 0.123
purine nucleoside triphosphate metabolic process GO:0009144 226 0.123
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.123
regulation of calcium ion transport GO:0051924 69 0.122
Mouse
embryonic organ morphogenesis GO:0048562 276 0.122
Mouse
glucose homeostasis GO:0042593 128 0.120
divalent inorganic cation homeostasis GO:0072507 138 0.119
purine containing compound metabolic process GO:0072521 311 0.119
nucleotide metabolic process GO:0009117 332 0.118
medulla oblongata development GO:0021550 3 0.116
nuclear division GO:0000280 158 0.116
hindbrain development GO:0030902 128 0.115
positive regulation of apoptotic process GO:0043065 217 0.115
regulation of cell cycle process GO:0010564 160 0.113
morphogenesis of a branching structure GO:0001763 203 0.112
regulation of transporter activity GO:0032409 57 0.112
Mouse
regulation of potassium ion transmembrane transport GO:1901379 11 0.110
endoplasmic reticulum organization GO:0007029 10 0.110
regulation of hormone levels GO:0010817 211 0.108
ribonucleotide metabolic process GO:0009259 291 0.108
calcium ion dependent exocytosis of neurotransmitter GO:0048791 7 0.107
nucleoside triphosphate metabolic process GO:0009141 230 0.106
cell communication involved in cardiac conduction GO:0086065 9 0.104
Mouse
regulation of synaptic plasticity GO:0048167 87 0.103
striated muscle myosin thick filament assembly GO:0071688 1 0.101
purine ribonucleotide metabolic process GO:0009150 290 0.100
carboxylic acid biosynthetic process GO:0046394 86 0.100
membrane organization GO:0061024 245 0.099
regulation of defense response GO:0031347 233 0.099
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.099
spinal cord development GO:0021510 81 0.098
cell differentiation in spinal cord GO:0021515 53 0.097
development of primary sexual characteristics GO:0045137 143 0.096
sensory perception GO:0007600 245 0.096
cellular metal ion homeostasis GO:0006875 151 0.095
hindbrain morphogenesis GO:0021575 46 0.095
regulation of neurotransmitter secretion GO:0046928 29 0.095
ear development GO:0043583 200 0.093
regulation of blood pressure GO:0008217 93 0.093
divalent inorganic cation transport GO:0072511 178 0.093
dna metabolic process GO:0006259 303 0.093
ribonucleoside monophosphate catabolic process GO:0009158 57 0.092
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.092
sensory perception of pain GO:0019233 47 0.092
ribonucleoside catabolic process GO:0042454 206 0.091
carbohydrate homeostasis GO:0033500 128 0.090
ion transmembrane transport GO:0034220 361 0.090
ear morphogenesis GO:0042471 118 0.089
regulation of anatomical structure size GO:0090066 178 0.089
cellular calcium ion homeostasis GO:0006874 119 0.089
heterocycle catabolic process GO:0046700 280 0.088
sulfur amino acid metabolic process GO:0000096 9 0.088
glycosyl compound metabolic process GO:1901657 246 0.088
regulation of purine nucleotide metabolic process GO:1900542 169 0.087
multicellular organismal signaling GO:0035637 91 0.085
Mouse
regulation of neurotransmitter transport GO:0051588 35 0.084
stem cell development GO:0048864 219 0.083
regulation of nucleoside metabolic process GO:0009118 130 0.082
cellular ion homeostasis GO:0006873 165 0.082
skeletal muscle cell differentiation GO:0035914 66 0.082
nucleoside phosphate catabolic process GO:1901292 222 0.082
purine nucleoside triphosphate catabolic process GO:0009146 203 0.081
potassium ion transmembrane transport GO:0071805 43 0.080
ventral spinal cord development GO:0021517 48 0.079
sulfur compound metabolic process GO:0006790 100 0.077
regulation of hydrolase activity GO:0051336 246 0.077
sensory perception of sound GO:0007605 97 0.077
neuron projection guidance GO:0097485 141 0.075
regionalization GO:0003002 337 0.075
atp metabolic process GO:0046034 75 0.074
sensory perception of mechanical stimulus GO:0050954 107 0.074
purine containing compound catabolic process GO:0072523 213 0.074
germ cell development GO:0007281 185 0.073
multi multicellular organism process GO:0044706 109 0.073
amide transport GO:0042886 138 0.072
glucose metabolic process GO:0006006 92 0.072
regulation of organelle organization GO:0033043 289 0.071
regulation of secretion by cell GO:1903530 249 0.071
heart contraction GO:0060047 93 0.071
Mouse Fly
purine nucleotide metabolic process GO:0006163 302 0.071
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.070
gland development GO:0048732 330 0.070
response to radiation GO:0009314 165 0.069
organ growth GO:0035265 117 0.069
meiotic nuclear division GO:0007126 115 0.069
cellular homeostasis GO:0019725 240 0.069
regulation of intracellular transport GO:0032386 159 0.069
Mouse
action potential GO:0001508 78 0.068
Mouse
myeloid cell differentiation GO:0030099 233 0.068
gliogenesis GO:0042063 141 0.068
monocarboxylic acid transport GO:0015718 44 0.068
regulation of ion transmembrane transporter activity GO:0032412 54 0.068
Mouse
regulation of exocytosis GO:0017157 61 0.067
regulation of muscle contraction GO:0006937 49 0.067
Mouse
monosaccharide metabolic process GO:0005996 106 0.067
nucleoside catabolic process GO:0009164 206 0.067
regulation of protein kinase activity GO:0045859 232 0.066
morphogenesis of a branching epithelium GO:0061138 193 0.065
regulation of body fluid levels GO:0050878 162 0.065
gamma aminobutyric acid signaling pathway GO:0007214 8 0.065
hexose metabolic process GO:0019318 98 0.064
organic acid biosynthetic process GO:0016053 86 0.064
carbohydrate derivative catabolic process GO:1901136 231 0.064
cerebellar cortex morphogenesis GO:0021696 32 0.064
organonitrogen compound catabolic process GO:1901565 264 0.063
purine nucleoside metabolic process GO:0042278 241 0.063
purine ribonucleotide catabolic process GO:0009154 208 0.063
cell differentiation in hindbrain GO:0021533 24 0.063
cellular response to hexose stimulus GO:0071331 47 0.063
membrane depolarization GO:0051899 64 0.062
heart morphogenesis GO:0003007 178 0.062
organic cyclic compound catabolic process GO:1901361 295 0.062
retina development in camera type eye GO:0060041 119 0.062
purine ribonucleoside catabolic process GO:0046130 205 0.062
purine nucleoside catabolic process GO:0006152 205 0.062
eating behavior GO:0042755 15 0.062
cellular nitrogen compound catabolic process GO:0044270 280 0.062
aromatic compound catabolic process GO:0019439 286 0.062
meiotic cell cycle GO:0051321 122 0.061
citrulline metabolic process GO:0000052 3 0.061
cell adhesion GO:0007155 329 0.060
glycosyl compound catabolic process GO:1901658 206 0.059
cell division GO:0051301 120 0.058
gamma aminobutyric acid secretion GO:0014051 6 0.058
digestive tract development GO:0048565 190 0.058
ossification GO:0001503 216 0.058
mesenchymal cell differentiation GO:0048762 107 0.058
inflammatory response GO:0006954 244 0.057
syncytium formation by plasma membrane fusion GO:0000768 42 0.057
insulin secretion GO:0030073 89 0.057
regulation of blood vessel size GO:0050880 56 0.056
cytoplasmic transport GO:0016482 234 0.056
cerebellum maturation GO:0021590 3 0.055
positive regulation of ion transport GO:0043270 65 0.055
Mouse
cellular ketone metabolic process GO:0042180 84 0.054
somitogenesis GO:0001756 69 0.054
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.054
Mouse
protein catabolic process GO:0030163 221 0.054
regulation of purine nucleotide catabolic process GO:0033121 122 0.054
musculoskeletal movement spinal reflex action GO:0050883 3 0.054
blood vessel morphogenesis GO:0048514 285 0.053
angiogenesis GO:0001525 201 0.053
organonitrogen compound biosynthetic process GO:1901566 192 0.053
positive regulation of ion transmembrane transport GO:0034767 24 0.053
Mouse
positive regulation of cell cycle process GO:0090068 61 0.053
embryonic skeletal system development GO:0048706 120 0.053
gonad development GO:0008406 141 0.052
protein localization to membrane GO:0072657 108 0.052
reproductive behavior GO:0019098 32 0.052
protein modification by small protein conjugation GO:0032446 187 0.052
positive regulation of cell development GO:0010720 237 0.051
peptide secretion GO:0002790 114 0.051
ribonucleoside monophosphate metabolic process GO:0009161 80 0.050
fatty acid biosynthetic process GO:0006633 41 0.050
muscle fiber development GO:0048747 76 0.050
regulation of cellular component biogenesis GO:0044087 181 0.050
response to light stimulus GO:0009416 135 0.050
histone modification GO:0016570 159 0.050
peptidyl amino acid modification GO:0018193 336 0.049
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.049
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.049
regulation of secretion GO:0051046 274 0.049
negative regulation of organelle organization GO:0010639 90 0.049
hormone secretion GO:0046879 128 0.049
neural precursor cell proliferation GO:0061351 121 0.049
regulation of proteolysis GO:0030162 164 0.048
cell recognition GO:0008037 83 0.048
olfactory learning GO:0008355 2 0.048
nucleoside triphosphate catabolic process GO:0009143 205 0.047
cytoskeleton dependent intracellular transport GO:0030705 50 0.047
cellular chloride ion homeostasis GO:0030644 1 0.047
myofibril assembly GO:0030239 34 0.047
neural tube development GO:0021915 160 0.047
camera type eye development GO:0043010 266 0.046
defense response to bacterium GO:0042742 119 0.046
multicellular organismal reproductive behavior GO:0033057 23 0.046
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.046
regulation of calcium ion dependent exocytosis GO:0017158 16 0.046
actin filament organization GO:0007015 113 0.046
mrna processing GO:0006397 63 0.046
nucleoside metabolic process GO:0009116 246 0.046
circulatory system process GO:0003013 197 0.046
Mouse Fly
phenol containing compound metabolic process GO:0018958 60 0.046
small molecule biosynthetic process GO:0044283 132 0.046
regulation of nucleotide catabolic process GO:0030811 122 0.046
regulation of actin cytoskeleton organization GO:0032956 84 0.045
cellular response to lipid GO:0071396 145 0.045
skeletal muscle myosin thick filament assembly GO:0030241 1 0.045
synapse assembly GO:0007416 56 0.045
hormone metabolic process GO:0042445 86 0.045
cellular response to dna damage stimulus GO:0006974 207 0.045
neural tube closure GO:0001843 90 0.044
cardiac muscle cell differentiation GO:0055007 69 0.044
gamma aminobutyric acid transport GO:0015812 7 0.044
multi organism behavior GO:0051705 62 0.044
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
sarcomere organization GO:0045214 24 0.043
macromolecule catabolic process GO:0009057 281 0.043
response to oxygen levels GO:0070482 62 0.043
Human Mouse
rna processing GO:0006396 105 0.043
protein modification by small protein conjugation or removal GO:0070647 207 0.043
cardiocyte differentiation GO:0035051 87 0.043
protein ubiquitination GO:0016567 171 0.043
regulation of protein localization GO:0032880 231 0.042
syncytium formation GO:0006949 43 0.042
neuromuscular process GO:0050905 99 0.042
sequestering of calcium ion GO:0051208 18 0.042
regulation of heart rate GO:0002027 36 0.042
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.042
negative regulation of cellular component organization GO:0051129 194 0.041
leukocyte mediated immunity GO:0002443 174 0.041
somite development GO:0061053 81 0.041
thyroid hormone metabolic process GO:0042403 16 0.041
telencephalon development GO:0021537 186 0.041
atp catabolic process GO:0006200 55 0.040
positive regulation of organelle organization GO:0010638 128 0.040
cell growth GO:0016049 130 0.040
regulation of organ growth GO:0046620 61 0.040
skeletal system morphogenesis GO:0048705 203 0.040
purine nucleoside monophosphate catabolic process GO:0009128 58 0.040
mesenchymal cell development GO:0014031 93 0.039
mitotic cell cycle GO:0000278 195 0.039
single organism cell adhesion GO:0098602 156 0.039
unsaturated fatty acid biosynthetic process GO:0006636 15 0.039
covalent chromatin modification GO:0016569 163 0.039
regulation of cellular ketone metabolic process GO:0010565 66 0.038
regulation of heart contraction GO:0008016 77 0.038
Mouse
regulation of cell cycle GO:0051726 281 0.038
regulation of cell adhesion GO:0030155 154 0.038
purine ribonucleoside metabolic process GO:0046128 241 0.038
adaptive immune response GO:0002250 155 0.037
regulation of wnt signaling pathway GO:0030111 123 0.037
regulation of sarcomere organization GO:0060297 4 0.037
mesenchyme development GO:0060485 152 0.036
regulation of retina development in camera type eye GO:1902866 3 0.036
cell cell signaling involved in cardiac conduction GO:0086019 6 0.036
Mouse
calcium ion dependent exocytosis GO:0017156 35 0.036
axon cargo transport GO:0008088 33 0.036
peptide transport GO:0015833 133 0.035
cerebellar purkinje cell layer formation GO:0021694 13 0.035
cellular lipid metabolic process GO:0044255 323 0.035
response to hypoxia GO:0001666 58 0.035
Human Mouse
protein oligomerization GO:0051259 67 0.035
stem cell differentiation GO:0048863 268 0.035
synapse organization GO:0050808 125 0.034
regulation of peptide transport GO:0090087 91 0.034
lymphocyte differentiation GO:0030098 242 0.034
microtubule based movement GO:0007018 84 0.034
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.034
positive regulation of kinase activity GO:0033674 155 0.034
nitrogen compound transport GO:0071705 271 0.033
skeletal muscle thin filament assembly GO:0030240 2 0.033
mitotic cell cycle process GO:1903047 159 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.033
regulation of peptide hormone secretion GO:0090276 75 0.033
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.033
female gamete generation GO:0007292 74 0.033
negative regulation of cell cycle GO:0045786 123 0.033
cardiac muscle fiber development GO:0048739 4 0.033
regulation of kinase activity GO:0043549 249 0.033
regulation of atp metabolic process GO:1903578 17 0.033
regulation of membrane repolarization GO:0060306 7 0.033
neuromuscular process controlling balance GO:0050885 59 0.033
myoblast differentiation GO:0045445 52 0.033
protein targeting GO:0006605 143 0.032
nucleotide catabolic process GO:0009166 217 0.032
anion homeostasis GO:0055081 16 0.032
negative regulation of molecular function GO:0044092 258 0.032
fear response GO:0042596 33 0.032
cardiac ventricle morphogenesis GO:0003208 50 0.032
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.032
mitochondrion distribution GO:0048311 4 0.032
rna splicing via transesterification reactions GO:0000375 43 0.032
cellular response to carbohydrate stimulus GO:0071322 50 0.032
neural tube formation GO:0001841 108 0.032
muscle filament sliding GO:0030049 1 0.032
positive regulation of apoptotic signaling pathway GO:2001235 95 0.031
regulation of peptide secretion GO:0002791 77 0.031
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.031
nucleotide biosynthetic process GO:0009165 78 0.031
leukocyte differentiation GO:0002521 342 0.031
positive regulation of proteolysis GO:0045862 85 0.031
spermatogenesis GO:0007283 284 0.031
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.031
conditioned taste aversion GO:0001661 4 0.031
regulation of multi organism process GO:0043900 111 0.031
lymphocyte mediated immunity GO:0002449 139 0.031
developmental cell growth GO:0048588 84 0.031
lipid biosynthetic process GO:0008610 179 0.030
cell fate commitment GO:0045165 210 0.030
positive regulation of neuron projection development GO:0010976 79 0.030
nucleoside monophosphate catabolic process GO:0009125 59 0.030
genitalia development GO:0048806 37 0.030
pallium development GO:0021543 120 0.030
monocarboxylic acid biosynthetic process GO:0072330 61 0.030
regulation of cytoskeleton organization GO:0051493 122 0.030
membrane repolarization GO:0086009 7 0.030
regulation of response to wounding GO:1903034 189 0.030
positive regulation of cell cycle GO:0045787 92 0.030
actin filament based movement GO:0030048 23 0.029
response to growth factor GO:0070848 198 0.029
positive regulation of nervous system development GO:0051962 221 0.029
neuron projection extension GO:1990138 64 0.029
visual perception GO:0007601 52 0.029
cellular monovalent inorganic anion homeostasis GO:0030320 4 0.029
oogenesis GO:0048477 56 0.029
regulation of hormone secretion GO:0046883 88 0.029
sequestering of metal ion GO:0051238 19 0.028
fluid transport GO:0042044 14 0.028
alpha amino acid metabolic process GO:1901605 59 0.028
positive regulation of transferase activity GO:0051347 167 0.028
hematopoietic progenitor cell differentiation GO:0002244 143 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
regulation of mrna processing GO:0050684 41 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
positive regulation of programmed cell death GO:0043068 218 0.027
Worm
reactive oxygen species metabolic process GO:0072593 84 0.027
sa node cell to atrial cardiac muscle cell communication GO:0086070 5 0.027
regulation of mapk cascade GO:0043408 248 0.027
chromatin organization GO:0006325 206 0.027
regulation of skeletal muscle contraction GO:0014819 3 0.027
positive regulation of epithelial cell proliferation GO:0050679 68 0.027
myeloid leukocyte differentiation GO:0002573 119 0.027
feeding behavior GO:0007631 62 0.026
regulation of protein serine threonine kinase activity GO:0071900 157 0.026
small gtpase mediated signal transduction GO:0007264 97 0.026
micturition GO:0060073 6 0.026
respiratory gaseous exchange GO:0007585 43 0.026
ceramide biosynthetic process GO:0046513 20 0.026
tube closure GO:0060606 91 0.026
neuron neuron synaptic transmission GO:0007270 69 0.026
protein import GO:0017038 101 0.026
oxidation reduction process GO:0055114 342 0.026
homeostasis of number of cells GO:0048872 210 0.026
exocytosis GO:0006887 121 0.026
heart process GO:0003015 94 0.025
Mouse Fly
regulation of lymphocyte mediated immunity GO:0002706 84 0.025
intrinsic apoptotic signaling pathway GO:0097193 132 0.025
regulation of adaptive immune response GO:0002819 90 0.025
regulation of striated muscle cell differentiation GO:0051153 81 0.025
cell matrix adhesion GO:0007160 68 0.025
rna splicing GO:0008380 54 0.025
microtubule based process GO:0007017 236 0.025
fatty acid derivative biosynthetic process GO:1901570 15 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025

Ryr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.953
Human
disease of anatomical entity DOID:7 0 0.953
Human
musculoskeletal system disease DOID:17 0 0.953
Human
muscle tissue disease DOID:66 0 0.953
Human
nervous system disease DOID:863 0 0.110
myopathy DOID:423 0 0.064
Human
distal arthrogryposis DOID:0050646 0 0.053
muscular dystrophy DOID:9884 0 0.034