Mus musculus

18 known processes

S1pr4

sphingosine-1-phosphate receptor 4

(Aliases: Edg6,Lpc1,MGC129298,S1p4)

S1pr4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lymphocyte differentiation GO:0030098 242 0.820
t cell differentiation GO:0030217 174 0.736
positive regulation of t cell activation GO:0050870 101 0.675
leukocyte differentiation GO:0002521 342 0.580
negative regulation of eosinophil degranulation GO:0043310 1 0.481
regulation of cell activation GO:0050865 289 0.478
antigen receptor mediated signaling pathway GO:0050851 64 0.453
amine metabolic process GO:0009308 45 0.427
leukocyte mediated immunity GO:0002443 174 0.408
positive regulation of protein modification process GO:0031401 299 0.368
Mouse
regulation of lymphocyte activation GO:0051249 240 0.363
regulation of cellular ketone metabolic process GO:0010565 66 0.352
myeloid cell activation involved in immune response GO:0002275 34 0.352
cellular amine metabolic process GO:0044106 44 0.352
cell chemotaxis GO:0060326 81 0.348
positive regulation of lymphocyte activation GO:0051251 140 0.347
g protein coupled receptor signaling pathway GO:0007186 243 0.334
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.331
wnt signaling pathway GO:0016055 188 0.330
t cell activation GO:0042110 289 0.326
regulation of adaptive immune response GO:0002819 90 0.326
regulation of cellular amine metabolic process GO:0033238 20 0.321
granulocyte chemotaxis GO:0071621 39 0.300
neuron projection guidance GO:0097485 141 0.299
leukocyte degranulation GO:0043299 27 0.293
regulation of t cell activation GO:0050863 170 0.284
positive regulation of transferase activity GO:0051347 167 0.282
Mouse
regulation of cytokine production GO:0001817 266 0.279
Mouse
regionalization GO:0003002 337 0.271
immune effector process GO:0002252 321 0.263
cellular extravasation GO:0045123 17 0.252
positive regulation of cellular amine metabolic process GO:0033240 5 0.249
cytokine production GO:0001816 319 0.248
Mouse
positive regulation of monocyte extravasation GO:2000439 1 0.244
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.244
positive regulation of kinase activity GO:0033674 155 0.241
Mouse
myeloid leukocyte activation GO:0002274 83 0.234
cardiac muscle tissue development GO:0048738 130 0.231
Mouse
thymic t cell selection GO:0045061 22 0.230
positive regulation of protein phosphorylation GO:0001934 242 0.216
Mouse
endomembrane system organization GO:0010256 147 0.216
peptidyl amino acid modification GO:0018193 336 0.215
hematopoietic stem cell migration GO:0035701 1 0.215
angiogenesis GO:0001525 201 0.213
Mouse
cell activation involved in immune response GO:0002263 126 0.210
regulation of immunological synapse formation GO:2000520 2 0.209
alpha beta t cell activation GO:0046631 91 0.204
neuronal action potential GO:0019228 54 0.204
telencephalon cell migration GO:0022029 55 0.203
positive regulation of cell activation GO:0050867 158 0.200
regulation of map kinase activity GO:0043405 120 0.195
Mouse
b cell activation GO:0042113 161 0.193
adaptive immune response GO:0002250 155 0.191
regulation of eosinophil degranulation GO:0043309 1 0.188
positive regulation of cell migration GO:0030335 109 0.187
cellular amino acid metabolic process GO:0006520 103 0.184
telencephalon development GO:0021537 186 0.184
regulation of secretion by cell GO:1903530 249 0.183
regulation of anatomical structure size GO:0090066 178 0.183
Mouse
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.181
regulation of cellular amino acid metabolic process GO:0006521 5 0.181
gamma delta t cell lineage commitment GO:0002365 1 0.180
leukocyte proliferation GO:0070661 172 0.179
forebrain development GO:0030900 302 0.179
lymphocyte proliferation GO:0046651 164 0.177
leukocyte activation involved in immune response GO:0002366 126 0.174
axonogenesis GO:0007409 274 0.172
Mouse
b cell proliferation GO:0042100 53 0.169
eosinophil activation GO:0043307 1 0.167
muscle tissue development GO:0060537 308 0.166
Mouse
leukocyte migration GO:0050900 124 0.165
Mouse
cytokine biosynthetic process GO:0042089 68 0.161
protein localization to organelle GO:0033365 185 0.161
negative regulation of immune system process GO:0002683 209 0.160
glial cell differentiation GO:0010001 131 0.160
microglial cell activation involved in immune response GO:0002282 1 0.157
helper t cell chemotaxis GO:0035704 1 0.156
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.155
blood vessel morphogenesis GO:0048514 285 0.155
Mouse
positive regulation of cytokine production GO:0001819 174 0.153
apoptotic signaling pathway GO:0097190 306 0.153
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.150
cellular ketone metabolic process GO:0042180 84 0.150
chemotaxis GO:0006935 247 0.148
Mouse
cerebral cortex cell migration GO:0021795 44 0.147
organelle localization GO:0051640 179 0.146
cell adhesion GO:0007155 329 0.145
Mouse
actin cytoskeleton organization GO:0030036 220 0.144
Mouse
leukocyte chemotaxis GO:0030595 69 0.143
positive regulation of leukocyte differentiation GO:1902107 86 0.142
myeloid leukocyte mediated immunity GO:0002444 42 0.141
positive regulation of mapk cascade GO:0043410 170 0.140
Mouse
regulated secretory pathway GO:0045055 32 0.138
negative regulation of protein metabolic process GO:0051248 282 0.138
cellular homeostasis GO:0019725 240 0.137
Mouse
defense response to bacterium GO:0042742 119 0.137
regulation of cell adhesion GO:0030155 154 0.136
Mouse
regulation of monocyte extravasation GO:2000437 2 0.134
eosinophil mediated immunity GO:0002447 1 0.133
interferon gamma production GO:0032609 67 0.132
formation of radial glial scaffolds GO:0021943 4 0.131
regulation of neuron projection development GO:0010975 169 0.128
Mouse
neuron migration GO:0001764 122 0.127
regulation of leukocyte differentiation GO:1902105 159 0.127
sensory organ morphogenesis GO:0090596 242 0.125
single organismal cell cell adhesion GO:0016337 131 0.125
regulation of leukocyte proliferation GO:0070663 121 0.125
t cell proliferation GO:0042098 120 0.125
macrophage activation GO:0042116 27 0.125
immune complex clearance GO:0002434 2 0.124
positive regulation of cell development GO:0010720 237 0.123
Mouse
cerebral cortex development GO:0021987 86 0.121
regulation of response to wounding GO:1903034 189 0.120
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.120
gliogenesis GO:0042063 141 0.120
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.116
regulation of mast cell degranulation GO:0043304 16 0.116
epithelial tube morphogenesis GO:0060562 303 0.114
mapk cascade GO:0000165 281 0.114
Mouse
negative regulation of cell activation GO:0050866 111 0.114
positive regulation of immunological synapse formation GO:2000522 1 0.113
endocytosis GO:0006897 168 0.113
regulation of apoptotic signaling pathway GO:2001233 197 0.113
lymphocyte mediated immunity GO:0002449 139 0.112
t cell differentiation in thymus GO:0033077 77 0.112
negative regulation of cell proliferation GO:0008285 296 0.112
regulation of leukocyte degranulation GO:0043300 20 0.111
negative regulation of immune effector process GO:0002698 55 0.109
single organism cell adhesion GO:0098602 156 0.109
positive regulation of secretion by cell GO:1903532 114 0.107
t cell selection GO:0045058 34 0.107
positive regulation of t cell costimulation GO:2000525 2 0.105
sequestering of calcium ion GO:0051208 18 0.105
mesodermal cell migration GO:0008078 4 0.104
morphogenesis of a branching structure GO:0001763 203 0.103
chemokine mediated signaling pathway GO:0070098 17 0.103
cell fate commitment GO:0045165 210 0.102
action potential GO:0001508 78 0.100
regulation of organ morphogenesis GO:2000027 144 0.100
regulation of cellular component size GO:0032535 121 0.099
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.099
Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.098
alpha beta t cell differentiation GO:0046632 69 0.098
inflammatory response GO:0006954 244 0.098
Mouse
regulation of phospholipase c activity GO:1900274 3 0.097
regulation of regulated secretory pathway GO:1903305 20 0.095
positive regulation of inflammatory response GO:0050729 47 0.095
positive regulation of chemotaxis GO:0050921 38 0.095
negative regulation of intracellular signal transduction GO:1902532 167 0.095
somite development GO:0061053 81 0.095
t cell extravasation GO:0072683 4 0.095
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.095
maintenance of location GO:0051235 89 0.094
substrate adhesion dependent cell spreading GO:0034446 30 0.094
sensory perception GO:0007600 245 0.094
protein catabolic process GO:0030163 221 0.094
cation transport GO:0006812 399 0.093
leukocyte cell cell adhesion GO:0007159 14 0.093
regulation of blood coagulation GO:0030193 28 0.092
regulation of kinase activity GO:0043549 249 0.092
Mouse
antigen processing and presentation GO:0019882 47 0.092
aromatic compound catabolic process GO:0019439 286 0.091
response to transforming growth factor beta GO:0071559 88 0.091
regulation of protein kinase activity GO:0045859 232 0.091
Mouse
regulation of t cell costimulation GO:2000523 2 0.091
negative regulation of apoptotic signaling pathway GO:2001234 104 0.091
positive regulation of cytokine biosynthetic process GO:0042108 40 0.091
monocyte extravasation GO:0035696 2 0.090
positive regulation of cell motility GO:2000147 116 0.090
small gtpase mediated signal transduction GO:0007264 97 0.090
Mouse
regulation of mast cell activation involved in immune response GO:0033006 17 0.089
regulation of dendritic cell chemotaxis GO:2000508 1 0.089
regulation of t cell extravasation GO:2000407 3 0.087
organelle fission GO:0048285 170 0.087
Mouse
synaptic transmission GO:0007268 329 0.087
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.087
cellular protein complex assembly GO:0043623 116 0.086
eosinophil activation involved in immune response GO:0002278 1 0.084
neutrophil migration GO:1990266 37 0.084
exocytosis GO:0006887 121 0.084
calcium mediated signaling GO:0019722 46 0.083
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.082
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.082
stress activated protein kinase signaling cascade GO:0031098 81 0.082
immune complex clearance by monocytes and macrophages GO:0002436 2 0.081
defense response to other organism GO:0098542 197 0.081
regulation of transferase activity GO:0051338 263 0.081
Mouse
embryonic placenta development GO:0001892 98 0.081
regulation of tumor necrosis factor production GO:0032680 49 0.081
positive regulation of lymphocyte proliferation GO:0050671 70 0.080
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.080
cognition GO:0050890 149 0.080
lymphocyte migration GO:0072676 26 0.080
Mouse
regulation of cytokine biosynthetic process GO:0042035 59 0.079
sequestering of metal ion GO:0051238 19 0.079
myeloid leukocyte differentiation GO:0002573 119 0.079
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.078
muscle cell differentiation GO:0042692 261 0.078
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.077
striated muscle tissue development GO:0014706 293 0.077
Mouse
embryonic organ morphogenesis GO:0048562 276 0.077
cytokine mediated signaling pathway GO:0019221 115 0.076
neutrophil chemotaxis GO:0030593 36 0.076
digestive tract morphogenesis GO:0048546 147 0.075
lamellipodium organization GO:0097581 29 0.075
Mouse
fatty acid biosynthetic process GO:0006633 41 0.074
regulation of cell projection organization GO:0031344 206 0.074
Mouse
positive regulation of organelle organization GO:0010638 128 0.074
germ cell development GO:0007281 185 0.074
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.074
mast cell activation GO:0045576 27 0.074
positive regulation of nervous system development GO:0051962 221 0.073
Mouse
macromolecule catabolic process GO:0009057 281 0.073
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.073
segmentation GO:0035282 93 0.072
regulation of body fluid levels GO:0050878 162 0.072
cardiac chamber development GO:0003205 108 0.072
regulation of leukocyte mediated immunity GO:0002703 104 0.072
membrane organization GO:0061024 245 0.072
stem cell maintenance GO:0019827 130 0.072
myeloid leukocyte migration GO:0097529 57 0.071
positive regulation of t cell extravasation GO:2000409 2 0.071
innate immune response GO:0045087 157 0.071
regulation of binding GO:0051098 111 0.071
microglial cell activation GO:0001774 3 0.070
cation homeostasis GO:0055080 212 0.070
Mouse
positive regulation of response to wounding GO:1903036 66 0.070
positive regulation of cellular catabolic process GO:0031331 148 0.070
ear development GO:0043583 200 0.070
regulation of alpha beta t cell activation GO:0046634 53 0.070
homeostasis of number of cells GO:0048872 210 0.069
negative regulation of adaptive immune response GO:0002820 25 0.068
regulation of interleukin 8 production GO:0032677 3 0.068
positive regulation of neutrophil chemotaxis GO:0090023 12 0.067
interleukin 12 secretion GO:0072610 3 0.067
eosinophil degranulation GO:0043308 1 0.067
negative regulation of macrophage apoptotic process GO:2000110 3 0.067
canonical wnt signaling pathway GO:0060070 130 0.066
endodermal cell fate specification GO:0001714 4 0.066
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.066
dendrite development GO:0016358 115 0.065
cellular lipid metabolic process GO:0044255 323 0.065
protein localization to nucleus GO:0034504 121 0.065
response to acid chemical GO:0001101 111 0.064
placenta development GO:0001890 140 0.064
positive regulation of cell adhesion GO:0045785 80 0.063
negative thymic t cell selection GO:0045060 12 0.063
actin filament organization GO:0007015 113 0.062
ameboidal type cell migration GO:0001667 128 0.062
regulation of endocytosis GO:0030100 69 0.062
t helper 17 cell chemotaxis GO:0035705 1 0.061
t cell receptor signaling pathway GO:0050852 46 0.061
regulation of hematopoietic stem cell migration GO:2000471 1 0.061
mast cell activation involved in immune response GO:0002279 20 0.061
negative regulation of protein phosphorylation GO:0001933 126 0.061
glycoprotein biosynthetic process GO:0009101 89 0.060
cell cell junction organization GO:0045216 72 0.060
interleukin 8 secretion GO:0072606 3 0.060
cell substrate adhesion GO:0031589 130 0.059
cytokine metabolic process GO:0042107 71 0.059
positive regulation of protein kinase activity GO:0045860 144 0.058
Mouse
digestive system development GO:0055123 200 0.058
divalent inorganic cation transport GO:0072511 178 0.058
associative learning GO:0008306 61 0.057
epithelial cell proliferation GO:0050673 174 0.057
positive regulation of monocyte chemotaxis GO:0090026 2 0.056
locomotory behavior GO:0007626 195 0.056
positive regulation of leukocyte proliferation GO:0070665 73 0.056
organelle assembly GO:0070925 177 0.055
positive regulation of secretion GO:0051047 130 0.055
guanosine containing compound metabolic process GO:1901068 144 0.055
acute inflammatory response GO:0002526 41 0.055
positive regulation of interleukin 8 secretion GO:2000484 1 0.055
nucleoside catabolic process GO:0009164 206 0.055
peptidyl tyrosine phosphorylation GO:0018108 143 0.054
establishment of protein localization to organelle GO:0072594 118 0.054
neural precursor cell proliferation GO:0061351 121 0.053
negative regulation of defense response GO:0031348 77 0.053
digestive tract development GO:0048565 190 0.053
b cell differentiation GO:0030183 78 0.053
exocrine system development GO:0035272 45 0.053
regulation of establishment of protein localization GO:0070201 181 0.053
multicellular organismal signaling GO:0035637 91 0.053
regulation of vesicle mediated transport GO:0060627 139 0.052
negative regulation of cytokine production GO:0001818 84 0.052
positive regulation of cell cycle GO:0045787 92 0.051
cardiac chamber morphogenesis GO:0003206 93 0.051
phospholipid metabolic process GO:0006644 87 0.051
divalent inorganic cation homeostasis GO:0072507 138 0.051
Mouse
positive regulation of interferon gamma production GO:0032729 39 0.051
cell growth GO:0016049 130 0.051
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.051
epithelial cell morphogenesis GO:0003382 41 0.051
ras protein signal transduction GO:0007265 77 0.050
Mouse
regulation of interleukin 8 secretion GO:2000482 2 0.050
rho protein signal transduction GO:0007266 32 0.050
Mouse
learning or memory GO:0007611 148 0.050
regulation of cell motility GO:2000145 236 0.050
learning GO:0007612 98 0.050
tumor necrosis factor biosynthetic process GO:0042533 10 0.050
regulation of b cell proliferation GO:0030888 39 0.050
nucleobase containing small molecule metabolic process GO:0055086 352 0.050
regulation of cellular component biogenesis GO:0044087 181 0.049
regulation of hemostasis GO:1900046 28 0.049
interleukin 8 production GO:0032637 4 0.049
positive regulation of nucleotide catabolic process GO:0030813 88 0.049
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.049
microtubule based process GO:0007017 236 0.049
regulation of mast cell activation GO:0033003 21 0.049
regulation of cell division GO:0051302 76 0.049
Mouse
gland development GO:0048732 330 0.049
ensheathment of neurons GO:0007272 76 0.048
positive regulation of t cell differentiation GO:0045582 52 0.048
morphogenesis of a branching epithelium GO:0061138 193 0.048
forebrain cell migration GO:0021885 58 0.048
morphogenesis of embryonic epithelium GO:0016331 159 0.048
monocarboxylic acid metabolic process GO:0032787 191 0.048
ossification GO:0001503 216 0.048
Mouse
t cell migration GO:0072678 19 0.048
Mouse
production of molecular mediator of immune response GO:0002440 103 0.047
response to extracellular stimulus GO:0009991 127 0.047
heart morphogenesis GO:0003007 178 0.047
Mouse
regulation of protein transport GO:0051223 163 0.047
regulation of t cell differentiation GO:0045580 83 0.047
tumor necrosis factor production GO:0032640 50 0.047
regulation of cellular response to stress GO:0080135 159 0.047
tolerance induction to self antigen GO:0002513 4 0.047
regulation of cell cycle GO:0051726 281 0.047
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.047
interleukin 2 production GO:0032623 33 0.046
t helper 1 type immune response GO:0042088 25 0.046
negative t cell selection GO:0043383 13 0.046
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.046
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.046
cellular nitrogen compound catabolic process GO:0044270 280 0.046
regulation of mapk cascade GO:0043408 248 0.046
Mouse
negative regulation of leukocyte mediated immunity GO:0002704 29 0.046
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.046
jnk cascade GO:0007254 72 0.045
nitrogen compound transport GO:0071705 271 0.045
cytoplasmic transport GO:0016482 234 0.045
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.045
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.045
stem cell development GO:0048864 219 0.045
regulation of homeostatic process GO:0032844 182 0.045
Mouse
regulation of embryonic development GO:0045995 71 0.045
regulation of actin filament polymerization GO:0030833 38 0.045
regulation of protein secretion GO:0050708 82 0.045
response to molecule of bacterial origin GO:0002237 143 0.044
regulation of acute inflammatory response GO:0002673 27 0.044
respiratory tube development GO:0030323 167 0.044
central nervous system neuron differentiation GO:0021953 162 0.044
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.044
regulation of hypersensitivity GO:0002883 10 0.044
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.044
regulation of voltage gated calcium channel activity GO:1901385 4 0.044
cellular divalent inorganic cation homeostasis GO:0072503 127 0.043
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.043
epithelial cell development GO:0002064 159 0.043
regulation of cell size GO:0008361 72 0.043
Mouse
cell junction organization GO:0034330 77 0.043
regulation of wound healing GO:0061041 40 0.043
regulation of protein complex assembly GO:0043254 83 0.043
immune response regulating signaling pathway GO:0002764 125 0.043
regulation of defense response GO:0031347 233 0.043
smoothened signaling pathway GO:0007224 105 0.043
cardiac septum development GO:0003279 59 0.042
t cell differentiation involved in immune response GO:0002292 30 0.042
myeloid cell homeostasis GO:0002262 114 0.042
mast cell degranulation GO:0043303 19 0.042
gastrulation GO:0007369 116 0.042
muscle cell proliferation GO:0033002 52 0.042
regulation of cell migration GO:0030334 219 0.042
positive regulation of cellular component biogenesis GO:0044089 94 0.042
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.041
negative regulation of cellular component organization GO:0051129 194 0.041
regulation of intracellular transport GO:0032386 159 0.041
regulation of b cell activation GO:0050864 81 0.041
regulation of wnt signaling pathway GO:0030111 123 0.041
labyrinthine layer development GO:0060711 49 0.041
granulocyte migration GO:0097530 43 0.040
positive regulation of behavior GO:0048520 40 0.040
bone resorption GO:0045453 38 0.040
Mouse
cell junction assembly GO:0034329 52 0.040
positive regulation of t cell proliferation GO:0042102 52 0.040
regulation of acute inflammatory response to antigenic stimulus GO:0002864 10 0.040
axon guidance GO:0007411 141 0.040
regulation of protein serine threonine kinase activity GO:0071900 157 0.040
Mouse
mature dendritic cell differentiation GO:0097029 3 0.039
homotypic cell cell adhesion GO:0034109 28 0.039
hypersensitivity GO:0002524 10 0.039
blood coagulation GO:0007596 76 0.039
regulation of neutrophil chemotaxis GO:0090022 14 0.039
viral gene expression GO:0019080 3 0.039
regulation of epithelial cell proliferation GO:0050678 141 0.039
positive regulation of nucleotide metabolic process GO:0045981 114 0.039
ear morphogenesis GO:0042471 118 0.039
cell maturation GO:0048469 127 0.039
cellular metal ion homeostasis GO:0006875 151 0.039
Mouse
wound healing GO:0042060 157 0.038
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.038
divalent metal ion transport GO:0070838 172 0.038
regulation of secretion GO:0051046 274 0.038
negative regulation of cell development GO:0010721 169 0.038
signal transduction in absence of ligand GO:0038034 55 0.038
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.038
response to lipopolysaccharide GO:0032496 128 0.037
protein polymerization GO:0051258 57 0.037
activation of immune response GO:0002253 138 0.037
antigen processing and presentation of exogenous antigen GO:0019884 26 0.037
regulation of angiogenesis GO:0045765 81 0.037
pallium development GO:0021543 120 0.037
erythrocyte differentiation GO:0030218 88 0.037
positive regulation of exocytosis GO:0045921 20 0.037
cochlea morphogenesis GO:0090103 22 0.037
skeletal muscle organ development GO:0060538 163 0.037
cell type specific apoptotic process GO:0097285 268 0.037
regulation of cytokine secretion GO:0050707 61 0.037
nucleotide metabolic process GO:0009117 332 0.037
single organism nuclear import GO:1902593 95 0.037
oocyte construction GO:0007308 2 0.037
positive regulation of neuron differentiation GO:0045666 141 0.036
Mouse
nephric duct formation GO:0072179 4 0.036
cerebral cortex radially oriented cell migration GO:0021799 31 0.036
actin polymerization or depolymerization GO:0008154 54 0.036
developmental maturation GO:0021700 193 0.036
Mouse
glucose homeostasis GO:0042593 128 0.036
Mouse
regulation of actin cytoskeleton organization GO:0032956 84 0.036
nuclear transport GO:0051169 139 0.036
regulation of interferon gamma production GO:0032649 57 0.036
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.036
circulatory system process GO:0003013 197 0.036
ribonucleotide metabolic process GO:0009259 291 0.035
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.035
regulation of exocytosis GO:0017157 61 0.035
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.035
positive regulation of map kinase activity GO:0043406 84 0.035
Mouse
regulation of jnk cascade GO:0046328 62 0.035
alpha beta t cell proliferation GO:0046633 21 0.035
regulation of ion homeostasis GO:2000021 64 0.035
cardiac ventricle development GO:0003231 83 0.035
regulation of neutrophil migration GO:1902622 14 0.035
cd4 positive alpha beta t cell activation GO:0035710 45 0.034
response to alcohol GO:0097305 48 0.034
regulation of chemotaxis GO:0050920 53 0.034
regulation of lymphocyte differentiation GO:0045619 107 0.034
positive regulation of alpha beta t cell activation GO:0046635 39 0.034
sensory perception of pain GO:0019233 47 0.034
positive regulation of granulocyte chemotaxis GO:0071624 12 0.034
peptidyl tyrosine modification GO:0018212 145 0.034
germ cell migration GO:0008354 8 0.034
response to organonitrogen compound GO:0010243 246 0.033
mitotic cell cycle GO:0000278 195 0.033
cellular defense response GO:0006968 6 0.033
acute inflammatory response to antigenic stimulus GO:0002438 12 0.033
anatomical structure homeostasis GO:0060249 145 0.033
Mouse
positive regulation of phospholipase c activity GO:0010863 2 0.033
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.033
jak stat cascade GO:0007259 42 0.033
nuclear division GO:0000280 158 0.033
Mouse
positive regulation of camp mediated signaling GO:0043950 3 0.033
regulation of calcium mediated signaling GO:0050848 19 0.032
regulation of protein binding GO:0043393 60 0.032
negative regulation of cellular amine metabolic process GO:0033239 1 0.032
positive regulation of neutrophil migration GO:1902624 12 0.032
microglia development GO:0014005 2 0.032
amide transport GO:0042886 138 0.032
ribonucleoside triphosphate metabolic process GO:0009199 220 0.032
ribose phosphate metabolic process GO:0019693 291 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
extrinsic apoptotic signaling pathway GO:0097191 126 0.032
regulation of neuron differentiation GO:0045664 281 0.032
Mouse
regulation of asymmetric cell division GO:0009786 4 0.032
second messenger mediated signaling GO:0019932 73 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
cellular chemical homeostasis GO:0055082 215 0.031
Mouse
release of sequestered calcium ion into cytosol GO:0051209 42 0.031
negative regulation of homeostatic process GO:0032845 71 0.031
lymphocyte activation involved in immune response GO:0002285 93 0.031
regulation of t helper 1 type immune response GO:0002825 17 0.031
interleukin 4 production GO:0032633 24 0.031
negative regulation of phosphorus metabolic process GO:0010563 184 0.031
hemostasis GO:0007599 78 0.031
glycosyl compound catabolic process GO:1901658 206 0.031
b cell activation involved in immune response GO:0002312 50 0.031
engulfment of apoptotic cell GO:0043652 3 0.031
response to nutrient levels GO:0031667 109 0.031
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.031
response to growth factor GO:0070848 198 0.030
positive regulation of adaptive immune response GO:0002821 61 0.030
protein secretion GO:0009306 111 0.030
negative regulation of response to wounding GO:1903035 77 0.030

S1pr4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.054
disease of anatomical entity DOID:7 0 0.054
hematopoietic system disease DOID:74 0 0.042
hemorrhagic disease DOID:2213 0 0.035
blood coagulation disease DOID:1247 0 0.035