Mus musculus

0 known processes

Sae1

SUMO1 activating enzyme subunit 1

(Aliases: Uble1a,D7Ertd177e,2610044L12Rik,2400010M20Rik,AW743391,AL033372,AOS1,HSPC140,Sua1)

Sae1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 115 0.789
meiotic cell cycle GO:0051321 122 0.461
recombinational repair GO:0000725 21 0.449
microtubule cytoskeleton organization GO:0000226 157 0.424
regulation of cell cycle GO:0051726 281 0.379
mitotic cell cycle GO:0000278 195 0.364
negative regulation of cell cycle process GO:0010948 69 0.311
nuclear division GO:0000280 158 0.298
meiotic cell cycle process GO:1903046 77 0.290
regulation of mitotic cell cycle phase transition GO:1901990 73 0.251
microtubule based process GO:0007017 236 0.235
mitotic cell cycle process GO:1903047 159 0.230
dna recombination GO:0006310 92 0.216
cellular nitrogen compound catabolic process GO:0044270 280 0.201
dna metabolic process GO:0006259 303 0.199
meiosis i GO:0007127 60 0.199
negative regulation of cell cycle GO:0045786 123 0.186
cellular response to dna damage stimulus GO:0006974 207 0.176
protein modification by small protein conjugation or removal GO:0070647 207 0.171
Human Zebrafish
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.169
organelle fission GO:0048285 170 0.166
protein complex disassembly GO:0043241 40 0.163
double strand break repair via homologous recombination GO:0000724 21 0.157
cell cycle checkpoint GO:0000075 47 0.149
mrna metabolic process GO:0016071 84 0.143
negative regulation of cellular component organization GO:0051129 194 0.138
regulation of protein localization GO:0032880 231 0.128
heterocycle catabolic process GO:0046700 280 0.127
regulation of mitotic cell cycle GO:0007346 126 0.124
cellular ketone metabolic process GO:0042180 84 0.121
cellular macromolecule catabolic process GO:0044265 206 0.120
regulation of intracellular transport GO:0032386 159 0.111
macromolecule catabolic process GO:0009057 281 0.111
positive regulation of dna templated transcription elongation GO:0032786 2 0.105
aromatic compound catabolic process GO:0019439 286 0.104
protein modification by small protein conjugation GO:0032446 187 0.103
Human Zebrafish
double strand break repair GO:0006302 48 0.095
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.095
regulation of cellular catabolic process GO:0031329 242 0.087
gtp catabolic process GO:0006184 143 0.086
regulation of cellular amine metabolic process GO:0033238 20 0.083
protein methylation GO:0006479 81 0.082
positive regulation of hydrolase activity GO:0051345 148 0.079
positive regulation of chromatin modification GO:1903310 28 0.079
organic cyclic compound catabolic process GO:1901361 295 0.078
regulation of organelle organization GO:0033043 289 0.074
methylation GO:0032259 134 0.073
regulation of cellular ketone metabolic process GO:0010565 66 0.073
chromatin organization GO:0006325 206 0.073
regulation of cell cycle process GO:0010564 160 0.071
cellular amine metabolic process GO:0044106 44 0.070
guanosine containing compound catabolic process GO:1901069 144 0.069
regulation of intracellular protein transport GO:0033157 82 0.069
regulation of chromatin modification GO:1903308 57 0.069
receptor mediated endocytosis GO:0006898 51 0.069
regulation of hydrolase activity GO:0051336 246 0.069
regulation of cytoplasmic transport GO:1903649 112 0.068
negative regulation of nuclear division GO:0051784 19 0.067
amine metabolic process GO:0009308 45 0.067
positive regulation of gtp catabolic process GO:0033126 85 0.066
cytoplasmic transport GO:0016482 234 0.065
peptidyl amino acid modification GO:0018193 336 0.065
spindle organization GO:0007051 28 0.064
endocytosis GO:0006897 168 0.063
mitotic cell cycle checkpoint GO:0007093 31 0.063
negative regulation of mitotic cell cycle GO:0045930 58 0.062
positive regulation of protein modification process GO:0031401 299 0.062
regulation of protein complex disassembly GO:0043244 28 0.061
positive regulation of cellular catabolic process GO:0031331 148 0.060
regulation of protein transport GO:0051223 163 0.059
regulation of nucleocytoplasmic transport GO:0046822 73 0.059
regulation of spindle organization GO:0090224 2 0.059
protein localization to nucleus GO:0034504 121 0.058
microtubule polymerization or depolymerization GO:0031109 26 0.057
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.056
gene silencing GO:0016458 38 0.056
regulation of transcription by chromatin organization GO:0034401 0 0.054
small gtpase mediated signal transduction GO:0007264 97 0.052
covalent chromatin modification GO:0016569 163 0.051
regulation of nucleotide catabolic process GO:0030811 122 0.051
positive regulation of cellular amine metabolic process GO:0033240 5 0.051
negative regulation of cell cycle phase transition GO:1901988 48 0.050
macromolecule methylation GO:0043414 120 0.050
negative regulation of cellular protein metabolic process GO:0032269 247 0.050
ras protein signal transduction GO:0007265 77 0.050
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.049
regulation of cell cycle phase transition GO:1901987 77 0.049
nucleocytoplasmic transport GO:0006913 139 0.049
synapsis GO:0007129 34 0.049
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
protein import GO:0017038 101 0.047
posttranscriptional regulation of gene expression GO:0010608 155 0.047
dna repair GO:0006281 107 0.047
development of primary sexual characteristics GO:0045137 143 0.046
microtubule nucleation GO:0007020 2 0.046
chromatin modification GO:0016568 187 0.045
nuclear transport GO:0051169 139 0.045
ribonucleoside triphosphate catabolic process GO:0009203 199 0.045
viral process GO:0016032 41 0.044
regulation of gtp catabolic process GO:0033124 113 0.044
guanosine containing compound metabolic process GO:1901068 144 0.043
regulation of ras gtpase activity GO:0032318 88 0.042
negative regulation of gene expression epigenetic GO:0045814 15 0.042
negative regulation of organelle organization GO:0010639 90 0.041
regulation of purine nucleotide catabolic process GO:0033121 122 0.041
reciprocal dna recombination GO:0035825 16 0.041
regulation of cellular protein catabolic process GO:1903362 61 0.040
gonad development GO:0008406 141 0.040
histone methylation GO:0016571 71 0.039
regulation of chromosome organization GO:0033044 83 0.039
organonitrogen compound catabolic process GO:1901565 264 0.038
regulation of meiotic cell cycle GO:0051445 34 0.038
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.038
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.036
negative regulation of cytoskeleton organization GO:0051494 36 0.036
organophosphate biosynthetic process GO:0090407 122 0.035
regulation of ras protein signal transduction GO:0046578 114 0.035
interspecies interaction between organisms GO:0044419 83 0.034
intracellular protein transport GO:0006886 204 0.034
protein ubiquitination GO:0016567 171 0.034
mitotic sister chromatid segregation GO:0000070 14 0.034
microtubule polymerization GO:0046785 12 0.033
protein localization to organelle GO:0033365 185 0.033
poly a mrna export from nucleus GO:0016973 4 0.033
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.033
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.032
positive regulation of nucleotide catabolic process GO:0030813 88 0.032
protein catabolic process GO:0030163 221 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
mitotic spindle organization GO:0007052 10 0.032
viral life cycle GO:0019058 36 0.032
rna splicing GO:0008380 54 0.032
macromolecular complex disassembly GO:0032984 43 0.031
dna templated transcription termination GO:0006353 4 0.030
purine nucleotide catabolic process GO:0006195 211 0.030
mitotic nuclear division GO:0007067 48 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.030
spindle assembly involved in female meiosis GO:0007056 3 0.029
regulation of multi organism process GO:0043900 111 0.029
chromosome organization involved in meiosis GO:0070192 39 0.029
telomere maintenance via telomerase GO:0007004 1 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
regulation of cytoskeleton organization GO:0051493 122 0.029
cellular protein complex assembly GO:0043623 116 0.028
rna dependent dna replication GO:0006278 3 0.028
telomere maintenance GO:0000723 19 0.028
regulation of microtubule based process GO:0032886 52 0.028
positive regulation of gtpase activity GO:0043547 85 0.027
spermatogenesis GO:0007283 284 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
negative regulation of protein complex disassembly GO:0043242 22 0.027
organelle assembly GO:0070925 177 0.027
stem cell differentiation GO:0048863 268 0.027
cell cycle g1 s phase transition GO:0044843 57 0.026
mrna splicing via spliceosome GO:0000398 43 0.026
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.026
dephosphorylation GO:0016311 129 0.026
cellular protein complex disassembly GO:0043624 36 0.026
positive regulation of histone modification GO:0031058 28 0.025
regulation of nuclear division GO:0051783 56 0.025
gtp metabolic process GO:0046039 144 0.025
rna processing GO:0006396 105 0.025
mrna processing GO:0006397 63 0.024
axonogenesis GO:0007409 274 0.024
chromosome segregation GO:0007059 48 0.024
deoxyribonucleotide biosynthetic process GO:0009263 6 0.024
regulation of protein import into nucleus GO:0042306 52 0.024
ribonucleoside metabolic process GO:0009119 245 0.023
dna damage checkpoint GO:0000077 26 0.023
negative regulation of multi organism process GO:0043901 68 0.023
nucleotide excision repair GO:0006289 13 0.023
positive regulation of nervous system development GO:0051962 221 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
microtubule based movement GO:0007018 84 0.023
maintenance of location GO:0051235 89 0.023
regulation of nucleoside metabolic process GO:0009118 130 0.022
chromatin silencing GO:0006342 15 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
negative regulation of viral process GO:0048525 23 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
nitrogen compound transport GO:0071705 271 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.022
regulation of histone modification GO:0031056 56 0.021
pore complex assembly GO:0046931 3 0.021
leukocyte proliferation GO:0070661 172 0.021
protein palmitoylation GO:0018345 14 0.021
cellular carbohydrate metabolic process GO:0044262 119 0.021
nucleotide catabolic process GO:0009166 217 0.021
dendrite development GO:0016358 115 0.021
cellular amino acid metabolic process GO:0006520 103 0.021
snorna metabolic process GO:0016074 1 0.021
rho protein signal transduction GO:0007266 32 0.020
cytokine mediated signaling pathway GO:0019221 115 0.020
chemotaxis GO:0006935 247 0.020
regulation of nuclear cell cycle dna replication GO:0033262 2 0.020
nucleoside catabolic process GO:0009164 206 0.020
germ cell development GO:0007281 185 0.020
carbohydrate metabolic process GO:0005975 230 0.020
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.019
negative regulation of immune system process GO:0002683 209 0.019
regulation of cell division GO:0051302 76 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
primary mirna processing GO:0031053 1 0.019
response to organic cyclic compound GO:0014070 198 0.019
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
regulation of protein catabolic process GO:0042176 108 0.019
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.019
molting cycle GO:0042303 90 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.018
reciprocal meiotic recombination GO:0007131 16 0.018
genitalia development GO:0048806 37 0.018
protein alkylation GO:0008213 81 0.018
mrna transport GO:0051028 13 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
nuclear export GO:0051168 34 0.017
positive regulation of ras gtpase activity GO:0032320 65 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
peptidyl lysine trimethylation GO:0018023 12 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
positive regulation of cell cycle GO:0045787 92 0.017
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.017
cellular lipid metabolic process GO:0044255 323 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
metaphase plate congression GO:0051310 2 0.017
protein targeting GO:0006605 143 0.017
regulation of rho gtpase activity GO:0032319 58 0.017
regulation of proteasomal protein catabolic process GO:0061136 46 0.016
cellular protein catabolic process GO:0044257 155 0.016
cellular response to organic cyclic compound GO:0071407 87 0.016
axon guidance GO:0007411 141 0.016
positive regulation of protein catabolic process GO:0045732 60 0.016
dna catabolic process endonucleolytic GO:0000737 15 0.016
homeostasis of number of cells GO:0048872 210 0.016
Zebrafish
response to inorganic substance GO:0010035 96 0.015
regulation of translation GO:0006417 71 0.015
trna wobble uridine modification GO:0002098 2 0.015
cation transport GO:0006812 399 0.015
muscle system process GO:0003012 141 0.015
dna conformation change GO:0071103 37 0.015
neuron migration GO:0001764 122 0.015
regulation of ran gtpase activity GO:0032316 3 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
histone modification GO:0016570 159 0.015
regulation of protein depolymerization GO:1901879 26 0.015
response to oxygen levels GO:0070482 62 0.015
microtubule depolymerization GO:0007019 15 0.014
mitotic recombination GO:0006312 3 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
nucleobase containing small molecule metabolic process GO:0055086 352 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
gene silencing by mirna GO:0035195 10 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
response to radiation GO:0009314 165 0.014
cell division GO:0051301 120 0.014
fertilization GO:0009566 127 0.014
meiotic cell cycle checkpoint GO:0033313 2 0.014
regulation of neuron projection development GO:0010975 169 0.014
dna integrity checkpoint GO:0031570 28 0.014
oogenesis GO:0048477 56 0.014
negative regulation of cell development GO:0010721 169 0.013
viral genome replication GO:0019079 17 0.013
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
single organism nuclear import GO:1902593 95 0.013
regulation of protein processing GO:0070613 96 0.013
negative regulation of cellular catabolic process GO:0031330 47 0.013
organophosphate catabolic process GO:0046434 232 0.013
non recombinational repair GO:0000726 10 0.013
dna replication GO:0006260 52 0.013
regulation of microtubule cytoskeleton organization GO:0070507 37 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
nuclear import GO:0051170 95 0.013
regulation of cellular response to stress GO:0080135 159 0.013
nucleus organization GO:0006997 45 0.013
regulation of cell motility GO:2000145 236 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
positive regulation of transferase activity GO:0051347 167 0.013
oxidation reduction process GO:0055114 342 0.013
protein import into nucleus GO:0006606 95 0.013
camera type eye development GO:0043010 266 0.013
lymphocyte proliferation GO:0046651 164 0.013
positive regulation of protein transport GO:0051222 93 0.013
regulation of glucose metabolic process GO:0010906 60 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
negative regulation of protein maturation GO:1903318 79 0.012
negative regulation of chromosome organization GO:2001251 30 0.012
rna splicing via transesterification reactions GO:0000375 43 0.012
sensory perception GO:0007600 245 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
centrosome organization GO:0051297 26 0.012
striated muscle contraction GO:0006941 45 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
regulation of secretion GO:0051046 274 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
neural precursor cell proliferation GO:0061351 121 0.012
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.012
regulation of hormone levels GO:0010817 211 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
single fertilization GO:0007338 82 0.012
mitotic centrosome separation GO:0007100 4 0.012
cell type specific apoptotic process GO:0097285 268 0.012
positive regulation of chromosome organization GO:2001252 33 0.012
negative regulation of protein processing GO:0010955 79 0.011
positive regulation of dna repair GO:0045739 3 0.011
mitotic cytokinesis GO:0000281 4 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
regulation of smad protein import into nucleus GO:0060390 3 0.011
response to iron ion GO:0010039 4 0.011
striated muscle tissue development GO:0014706 293 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
negative regulation of proteolysis GO:0045861 74 0.011
ribose phosphate metabolic process GO:0019693 291 0.011
skin development GO:0043588 220 0.011
nucleotide metabolic process GO:0009117 332 0.011
regulation of cell projection organization GO:0031344 206 0.011
negative regulation of viral genome replication GO:0045071 10 0.011
protein maturation GO:0051604 176 0.011
sequestering of calcium ion GO:0051208 18 0.011
cellular chemical homeostasis GO:0055082 215 0.011
regulation of proteolysis GO:0030162 164 0.011
muscle tissue development GO:0060537 308 0.011
cell adhesion GO:0007155 329 0.011
dna modification GO:0006304 50 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
negative regulation of intracellular transport GO:0032387 38 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
female meiosis i GO:0007144 7 0.011
divalent metal ion transport GO:0070838 172 0.010
negative regulation of molecular function GO:0044092 258 0.010
cellular response to lipid GO:0071396 145 0.010
multi multicellular organism process GO:0044706 109 0.010
cellularization GO:0007349 1 0.010
transmembrane transport GO:0055085 412 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
hormone secretion GO:0046879 128 0.010
cellular homeostasis GO:0019725 240 0.010
negative regulation of dna templated transcription termination GO:0060567 1 0.010
regulation of mrna splicing via spliceosome GO:0048024 32 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010

Sae1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.011
eye and adnexa disease DOID:1492 0 0.011
sensory system disease DOID:0050155 0 0.011
nervous system disease DOID:863 0 0.011
eye disease DOID:5614 0 0.011
disease of anatomical entity DOID:7 0 0.011
colon cancer DOID:219 0 0.010
large intestine cancer DOID:5672 0 0.010
cancer DOID:162 0 0.010
gastrointestinal system cancer DOID:3119 0 0.010
intestinal cancer DOID:10155 0 0.010
colorectal cancer DOID:9256 0 0.010
organ system cancer DOID:0050686 0 0.010
disease of cellular proliferation DOID:14566 0 0.010