Mus musculus

0 known processes

Sap18

Sin3-associated polypeptide 18

(Aliases: C530046K05Rik,EMegR4,D11Ertd539e,Sinbp1)

Sap18 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ubiquitin dependent protein catabolic process GO:0006511 129 0.629
modification dependent protein catabolic process GO:0019941 133 0.389
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.370
modification dependent macromolecule catabolic process GO:0043632 133 0.366
cellular macromolecule catabolic process GO:0044265 206 0.366
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.345
regulation of cellular protein catabolic process GO:1903362 61 0.244
protein catabolic process GO:0030163 221 0.222
cytoplasmic transport GO:0016482 234 0.220
negative regulation of molecular function GO:0044092 258 0.209
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.170
regulation of protein sumoylation GO:0033233 4 0.161
cellular protein catabolic process GO:0044257 155 0.154
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.148
protein modification by small protein conjugation or removal GO:0070647 207 0.145
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.141
protein localization to organelle GO:0033365 185 0.141
macromolecule catabolic process GO:0009057 281 0.138
regionalization GO:0003002 337 0.135
regulation of cellular catabolic process GO:0031329 242 0.128
cellular response to dna damage stimulus GO:0006974 207 0.122
negative regulation of cellular protein catabolic process GO:1903363 22 0.121
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.120
protein modification by small protein conjugation GO:0032446 187 0.119
negative regulation of protein catabolic process GO:0042177 36 0.115
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.105
innate immune response GO:0045087 157 0.103
establishment of protein localization to organelle GO:0072594 118 0.099
regulation of protein localization GO:0032880 231 0.093
intrinsic apoptotic signaling pathway GO:0097193 132 0.092
positive regulation of apoptotic signaling pathway GO:2001235 95 0.091
appendage development GO:0048736 166 0.091
regulation of cell cycle GO:0051726 281 0.085
negative regulation of transcription factor import into nucleus GO:0042992 13 0.083
apoptotic signaling pathway GO:0097190 306 0.082
regulation of protein catabolic process GO:0042176 108 0.080
nucleocytoplasmic transport GO:0006913 139 0.079
positive regulation of innate immune response GO:0045089 80 0.077
negative regulation of cell cycle GO:0045786 123 0.075
protein localization to nucleus GO:0034504 121 0.074
smoothened signaling pathway GO:0007224 105 0.074
positive regulation of proteolysis GO:0045862 85 0.074
regulation of cellular response to stress GO:0080135 159 0.073
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.072
ventral spinal cord interneuron differentiation GO:0021514 16 0.069
defense response to other organism GO:0098542 197 0.067
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 12 0.066
camera type eye development GO:0043010 266 0.065
regulation of apoptotic signaling pathway GO:2001233 197 0.063
embryonic epithelial tube formation GO:0001838 130 0.062
compound eye development GO:0048749 1 0.060
protein targeting GO:0006605 143 0.060
cell fate specification involved in pattern specification GO:0060573 11 0.059
regulation of mitotic cell cycle phase transition GO:1901990 73 0.059
regulation of binding GO:0051098 111 0.059
single organism nuclear import GO:1902593 95 0.058
multicellular organism growth GO:0035264 161 0.058
negative regulation of nervous system development GO:0051961 156 0.058
positive regulation of protein sumoylation GO:0033235 3 0.058
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 14 0.058
intracellular protein transport GO:0006886 204 0.057
protein maturation GO:0051604 176 0.057
skin development GO:0043588 220 0.056
regulation of proteasomal protein catabolic process GO:0061136 46 0.056
regulation of intracellular transport GO:0032386 159 0.055
protein import GO:0017038 101 0.055
regulation of innate immune response GO:0045088 91 0.055
protein import into nucleus GO:0006606 95 0.054
central nervous system neuron differentiation GO:0021953 162 0.054
nuclear transport GO:0051169 139 0.053
defense response to bacterium GO:0042742 119 0.052
regulation of protein processing GO:0070613 96 0.051
epithelial tube morphogenesis GO:0060562 303 0.051
cellular amine metabolic process GO:0044106 44 0.050
tube formation GO:0035148 140 0.050
gonad development GO:0008406 141 0.050
regulation of transcription from rna polymerase ii promoter by galactose GO:0000431 1 0.050
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.049
regulation of response to drug GO:2001023 2 0.049
defense response to gram negative bacterium GO:0050829 28 0.046
regulation of embryonic development GO:0045995 71 0.046
regulation of cytoplasmic transport GO:1903649 112 0.046
dorsal ventral neural tube patterning GO:0021904 28 0.046
positive regulation of programmed cell death GO:0043068 218 0.045
regulation of protein binding GO:0043393 60 0.044
negative regulation of protein import into nucleus GO:0042308 21 0.044
spinal cord development GO:0021510 81 0.044
maintenance of location GO:0051235 89 0.044
amine metabolic process GO:0009308 45 0.044
regulation of protein transport GO:0051223 163 0.043
dna packaging GO:0006323 30 0.043
neural tube closure GO:0001843 90 0.042
regulation of establishment of protein localization GO:0070201 181 0.042
protein sumoylation GO:0016925 14 0.041
negative regulation of protein modification process GO:0031400 163 0.041
embryonic organ morphogenesis GO:0048562 276 0.040
dna conformation change GO:0071103 37 0.040
ventral spinal cord interneuron fate commitment GO:0060579 14 0.040
negative regulation of cell cycle process GO:0010948 69 0.039
regulation of protein ubiquitination GO:0031396 52 0.039
digestive tract development GO:0048565 190 0.037
cytoplasmic sequestering of transcription factor GO:0042994 5 0.037
regulation of protein targeting GO:1903533 61 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.037
ventral spinal cord development GO:0021517 48 0.037
negative regulation of protein maturation GO:1903318 79 0.036
regulation of cell cycle phase transition GO:1901987 77 0.036
nuclear import GO:0051170 95 0.036
regulation of nucleocytoplasmic transport GO:0046822 73 0.036
histone modification GO:0016570 159 0.036
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.036
cell differentiation in spinal cord GO:0021515 53 0.035
ventral spinal cord interneuron specification GO:0021521 11 0.035
transmembrane transport GO:0055085 412 0.035
negative regulation of cellular catabolic process GO:0031330 47 0.035
epithelial tube formation GO:0072175 130 0.035
negative regulation of intracellular protein transport GO:0090317 27 0.034
spinal cord motor neuron differentiation GO:0021522 35 0.034
regulation of protein import into nucleus GO:0042306 52 0.034
neural tube development GO:0021915 160 0.033
positive regulation of defense response GO:0031349 124 0.033
negative regulation of protein metabolic process GO:0051248 282 0.033
regulation of transmembrane transport GO:0034762 128 0.033
positive regulation of apoptotic process GO:0043065 217 0.032
positive regulation of transcription from rna polymerase ii promoter by galactose GO:0000435 1 0.032
positive regulation of growth GO:0045927 104 0.032
determination of left right symmetry GO:0007368 80 0.032
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.032
regulation of transcription factor import into nucleus GO:0042990 24 0.032
negative regulation of proteolysis GO:0045861 74 0.031
negative regulation of binding GO:0051100 39 0.031
negative regulation of intracellular transport GO:0032387 38 0.030
peptidyl amino acid modification GO:0018193 336 0.030
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 6 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
negative regulation of protein localization to nucleus GO:1900181 23 0.029
positive regulation of cellular protein catabolic process GO:1903364 34 0.029
development of primary sexual characteristics GO:0045137 143 0.029
pharynx development GO:0060465 1 0.028
negative regulation of smoothened signaling pathway GO:0045879 25 0.027
lens development in camera type eye GO:0002088 62 0.027
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.027
negative regulation of cytoplasmic transport GO:1903650 29 0.027
regulation of cell cycle process GO:0010564 160 0.027
protein acylation GO:0043543 64 0.026
embryonic heart tube morphogenesis GO:0003143 51 0.026
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.026
small gtpase mediated signal transduction GO:0007264 97 0.025
organelle fission GO:0048285 170 0.025
regulation of osteoblast differentiation GO:0045667 67 0.025
protein processing GO:0016485 163 0.025
tube closure GO:0060606 91 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
cell fate commitment involved in pattern specification GO:0060581 14 0.025
primary neural tube formation GO:0014020 95 0.025
wnt signaling pathway GO:0016055 188 0.024
organophosphate biosynthetic process GO:0090407 122 0.024
regulation of protein localization to nucleus GO:1900180 60 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
regulation of smoothened signaling pathway GO:0008589 58 0.024
limb development GO:0060173 166 0.024
regulation of protein maturation GO:1903317 96 0.024
regulation of intracellular protein transport GO:0033157 82 0.023
muscle cell differentiation GO:0042692 261 0.023
embryonic heart tube development GO:0035050 65 0.023
neural tube patterning GO:0021532 43 0.023
morphogenesis of embryonic epithelium GO:0016331 159 0.023
neuron fate specification GO:0048665 30 0.023
nuclear division GO:0000280 158 0.023
ion transmembrane transport GO:0034220 361 0.022
spinal cord dorsal ventral patterning GO:0021513 23 0.022
negative regulation of protein processing GO:0010955 79 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
carbon catabolite activation of transcription GO:0045991 4 0.022
determination of heart left right asymmetry GO:0061371 48 0.022
cellular amino acid metabolic process GO:0006520 103 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
neural precursor cell proliferation GO:0061351 121 0.022
oxidation reduction process GO:0055114 342 0.021
chromatin organization GO:0006325 206 0.021
negative regulation of protein ubiquitination GO:0031397 19 0.021
negative regulation of mitotic cell cycle GO:0045930 58 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902229 14 0.021
connective tissue development GO:0061448 179 0.021
cell type specific apoptotic process GO:0097285 268 0.020
spinal cord patterning GO:0021511 25 0.020
nitrogen compound transport GO:0071705 271 0.020
regulation of cell migration GO:0030334 219 0.020
regulation of secretion by cell GO:1903530 249 0.020
heterocycle catabolic process GO:0046700 280 0.020
mapk cascade GO:0000165 281 0.020
regulation of proteolysis GO:0030162 164 0.019
regulation of membrane potential GO:0042391 192 0.019
positive regulation of protein modification process GO:0031401 299 0.019
chromatin modification GO:0016568 187 0.019
negative regulation of nf kappab transcription factor activity GO:0032088 15 0.019
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.019
protein ubiquitination GO:0016567 171 0.019
leukocyte mediated cytotoxicity GO:0001909 62 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
lymphocyte proliferation GO:0046651 164 0.019
dna repair GO:0006281 107 0.019
transcription factor import into nucleus GO:0042991 26 0.018
regulation of ion transmembrane transport GO:0034765 119 0.018
ras protein signal transduction GO:0007265 77 0.018
regulation of response to dna damage stimulus GO:2001020 34 0.018
cation transmembrane transport GO:0098655 266 0.018
membrane organization GO:0061024 245 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
epidermis development GO:0008544 187 0.017
regulation of neuron differentiation GO:0045664 281 0.017
calcium ion transport GO:0006816 159 0.017
regulation of protein serine threonine kinase activity GO:0071900 157 0.017
nucleotide metabolic process GO:0009117 332 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
positive regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902231 6 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
spermatogenesis GO:0007283 284 0.016
cell fate commitment GO:0045165 210 0.016
limb morphogenesis GO:0035108 149 0.016
negative regulation of protein binding GO:0032091 17 0.016
divalent metal ion transport GO:0070838 172 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
forebrain development GO:0030900 302 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
lipid biosynthetic process GO:0008610 179 0.016
striated muscle tissue development GO:0014706 293 0.016
skeletal system development GO:0001501 356 0.016
immune response activating signal transduction GO:0002757 116 0.016
asymmetric stem cell division GO:0098722 3 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
circulatory system process GO:0003013 197 0.015
cation transport GO:0006812 399 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
chemotaxis GO:0006935 247 0.015
spinal cord motor neuron cell fate specification GO:0021520 13 0.015
positive regulation of transcription by galactose GO:0000411 1 0.015
gland development GO:0048732 330 0.015
cell cycle checkpoint GO:0000075 47 0.015
appendage morphogenesis GO:0035107 149 0.015
cartilage development GO:0051216 140 0.014
negative regulation of cell development GO:0010721 169 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
keratinocyte differentiation GO:0030216 48 0.014
histone lysine methylation GO:0034968 50 0.014
urogenital system development GO:0001655 261 0.014
regulation of defense response GO:0031347 233 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
regulation of hormone levels GO:0010817 211 0.014
immune effector process GO:0002252 321 0.014
renal system development GO:0072001 225 0.014
cellular homeostasis GO:0019725 240 0.014
myeloid cell differentiation GO:0030099 233 0.014
sequestering of metal ion GO:0051238 19 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 23 0.013
rna processing GO:0006396 105 0.013
translation GO:0006412 93 0.013
regulation of secretion GO:0051046 274 0.013
mrna metabolic process GO:0016071 84 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
endocytosis GO:0006897 168 0.013
macromolecule methylation GO:0043414 120 0.013
cellular chemical homeostasis GO:0055082 215 0.013
regulation of organelle organization GO:0033043 289 0.013
digestive system development GO:0055123 200 0.013
respiratory system development GO:0060541 190 0.013
response to nutrient levels GO:0031667 109 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
smoothened signaling pathway involved in ventral spinal cord patterning GO:0021910 7 0.013
regulation of calcium ion transport GO:0051924 69 0.013
mitochondrion organization GO:0007005 134 0.013
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.013
ossification GO:0001503 216 0.013
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.013
muscle tissue development GO:0060537 308 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
epithelial cell proliferation GO:0050673 174 0.013
genitalia development GO:0048806 37 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
nucleoside metabolic process GO:0009116 246 0.012
male gamete generation GO:0048232 285 0.012
response to oxidative stress GO:0006979 123 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
covalent chromatin modification GO:0016569 163 0.012
regulation of nuclear division GO:0051783 56 0.012
t cell proliferation GO:0042098 120 0.012
protein polyubiquitination GO:0000209 33 0.012
regulation of cellular amino acid metabolic process GO:0006521 5 0.012
amide transport GO:0042886 138 0.012
purine containing compound catabolic process GO:0072523 213 0.012
regulation of cellular ketone metabolic process GO:0010565 66 0.012
regulation of meiotic cell cycle GO:0051445 34 0.012
rho protein signal transduction GO:0007266 32 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
cellular response to cadmium ion GO:0071276 3 0.012
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.012
bone development GO:0060348 120 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
respiratory tube development GO:0030323 167 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
meiotic nuclear division GO:0007126 115 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
intracellular mrna localization GO:0008298 4 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
regulation of mapk cascade GO:0043408 248 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of cell migration GO:0030335 109 0.011
negative regulation of immune system process GO:0002683 209 0.011
regulation of translation GO:0006417 71 0.011
epithelial cell development GO:0002064 159 0.011
substantia nigra development GO:0021762 2 0.011
positive regulation of transferase activity GO:0051347 167 0.011
cellular ketone metabolic process GO:0042180 84 0.011
gene silencing GO:0016458 38 0.011
mitotic cell cycle GO:0000278 195 0.011
fat cell differentiation GO:0045444 160 0.011
myeloid cell homeostasis GO:0002262 114 0.010
lung development GO:0030324 164 0.010
blood circulation GO:0008015 195 0.010
lipid localization GO:0010876 126 0.010
mitotic cell cycle checkpoint GO:0007093 31 0.010
leukocyte differentiation GO:0002521 342 0.010
regulation of cell growth GO:0001558 91 0.010
regulation of cell activation GO:0050865 289 0.010
glycoprotein metabolic process GO:0009100 116 0.010
metal ion homeostasis GO:0055065 189 0.010
meiotic cell cycle GO:0051321 122 0.010

Sap18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.214
cancer DOID:162 0 0.205
organ system cancer DOID:0050686 0 0.205
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.020