Mus musculus

30 known processes

Scmh1

sex comb on midleg homolog 1

(Aliases: AI315320,Scml3,Scml1,AI851618)

Scmh1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium assembly GO:0042384 81 0.830
cilium morphogenesis GO:0060271 102 0.758
cell cycle comprising mitosis without cytokinesis GO:0033301 1 0.368
protein modification by small protein conjugation or removal GO:0070647 207 0.235
chromatin modification GO:0016568 187 0.183
response to organic cyclic compound GO:0014070 198 0.176
protein ubiquitination GO:0016567 171 0.168
cellular component assembly involved in morphogenesis GO:0010927 139 0.160
leukocyte differentiation GO:0002521 342 0.146
histone modification GO:0016570 159 0.137
regionalization GO:0003002 337 0.116
embryonic organ morphogenesis GO:0048562 276 0.116
male gamete generation GO:0048232 285 0.113
central nervous system neuron differentiation GO:0021953 162 0.112
skeletal system development GO:0001501 356 0.101
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.093
mitotic cell cycle GO:0000278 195 0.087
gland development GO:0048732 330 0.078
regulation of cell cycle GO:0051726 281 0.074
cellular response to lipid GO:0071396 145 0.074
epithelial cell proliferation GO:0050673 174 0.071
response to sterol GO:0036314 4 0.068
embryonic skeletal system development GO:0048706 120 0.067
nucleotide metabolic process GO:0009117 332 0.067
macromolecule catabolic process GO:0009057 281 0.066
spermatogenesis GO:0007283 284 0.065
regulation of cellular amino acid metabolic process GO:0006521 5 0.064
proteasomal protein catabolic process GO:0010498 98 0.064
transmembrane transport GO:0055085 412 0.063
positive regulation of immature t cell proliferation GO:0033091 4 0.063
neural tube development GO:0021915 160 0.062
ion transmembrane transport GO:0034220 361 0.060
ribonucleotide metabolic process GO:0009259 291 0.060
cellular response to acid chemical GO:0071229 68 0.060
purine containing compound metabolic process GO:0072521 311 0.060
nucleobase containing small molecule metabolic process GO:0055086 352 0.060
ribose phosphate metabolic process GO:0019693 291 0.057
cellular response to retinoic acid GO:0071300 25 0.056
nucleoside phosphate metabolic process GO:0006753 338 0.056
small gtpase mediated signal transduction GO:0007264 97 0.055
protein catabolic process GO:0030163 221 0.055
covalent chromatin modification GO:0016569 163 0.054
response to acid chemical GO:0001101 111 0.052
renal system development GO:0072001 225 0.051
organelle assembly GO:0070925 177 0.051
response to retinoic acid GO:0032526 56 0.050
circadian rhythm GO:0007623 114 0.050
blood vessel morphogenesis GO:0048514 285 0.048
muscle tissue development GO:0060537 308 0.048
negative regulation of nervous system development GO:0051961 156 0.047
developmental maturation GO:0021700 193 0.047
central nervous system neuron development GO:0021954 67 0.045
spinal cord development GO:0021510 81 0.045
gene silencing GO:0016458 38 0.044
Fly
regulation of cellular ketone metabolic process GO:0010565 66 0.044
homeostasis of number of cells GO:0048872 210 0.042
hepaticobiliary system development GO:0061008 67 0.041
urogenital system development GO:0001655 261 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.040
regulation of ion transmembrane transport GO:0034765 119 0.040
sensory perception GO:0007600 245 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.039
carbohydrate metabolic process GO:0005975 230 0.039
ribonucleoside triphosphate metabolic process GO:0009199 220 0.039
nucleotide catabolic process GO:0009166 217 0.039
ras protein signal transduction GO:0007265 77 0.038
liver development GO:0001889 66 0.038
carbohydrate homeostasis GO:0033500 128 0.038
axonogenesis GO:0007409 274 0.038
Fly
angiogenesis GO:0001525 201 0.037
carbohydrate derivative catabolic process GO:1901136 231 0.037
mitotic cell cycle embryonic GO:0045448 5 0.037
modification dependent protein catabolic process GO:0019941 133 0.037
divalent inorganic cation transport GO:0072511 178 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.037
stem cell development GO:0048864 219 0.036
regulation of organelle organization GO:0033043 289 0.036
regulation of neuron differentiation GO:0045664 281 0.036
purine nucleoside triphosphate metabolic process GO:0009144 226 0.036
cellular ketone metabolic process GO:0042180 84 0.035
epidermis development GO:0008544 187 0.035
cation transmembrane transport GO:0098655 266 0.035
chromatin organization GO:0006325 206 0.035
morphogenesis of a branching epithelium GO:0061138 193 0.035
regulation of wnt signaling pathway GO:0030111 123 0.035
neural tube closure GO:0001843 90 0.034
embryonic skeletal system morphogenesis GO:0048704 91 0.034
lung development GO:0030324 164 0.034
protein modification by small protein conjugation GO:0032446 187 0.033
smoothened signaling pathway GO:0007224 105 0.033
inorganic cation transmembrane transport GO:0098662 207 0.033
gtp catabolic process GO:0006184 143 0.032
ribonucleoside catabolic process GO:0042454 206 0.032
cellular protein catabolic process GO:0044257 155 0.032
organic cyclic compound catabolic process GO:1901361 295 0.032
aromatic compound catabolic process GO:0019439 286 0.032
exocytosis GO:0006887 121 0.032
cellular nitrogen compound catabolic process GO:0044270 280 0.032
primary neural tube formation GO:0014020 95 0.032
modification dependent macromolecule catabolic process GO:0043632 133 0.031
regulation of protein stability GO:0031647 52 0.031
action potential GO:0001508 78 0.031
inorganic ion transmembrane transport GO:0098660 234 0.031
protein targeting GO:0006605 143 0.031
cytoplasmic transport GO:0016482 234 0.031
skin development GO:0043588 220 0.030
wnt signaling pathway GO:0016055 188 0.029
neural tube formation GO:0001841 108 0.029
regulation of secretion GO:0051046 274 0.029
cellular macromolecule catabolic process GO:0044265 206 0.029
myeloid cell differentiation GO:0030099 233 0.029
regulation of exocytosis GO:0017157 61 0.029
regulation of intracellular transport GO:0032386 159 0.029
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.029
glycosyl compound catabolic process GO:1901658 206 0.028
ubiquitin dependent protein catabolic process GO:0006511 129 0.028
carbohydrate biosynthetic process GO:0016051 74 0.028
intracellular protein transport GO:0006886 204 0.028
cation transport GO:0006812 399 0.028
morphogenesis of embryonic epithelium GO:0016331 159 0.027
organophosphate catabolic process GO:0046434 232 0.027
dna repair GO:0006281 107 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.026
nitrogen compound transport GO:0071705 271 0.026
t cell activation GO:0042110 289 0.026
positive regulation of cell activation GO:0050867 158 0.025
skeletal system morphogenesis GO:0048705 203 0.025
regulation of cellular catabolic process GO:0031329 242 0.025
cellular amine metabolic process GO:0044106 44 0.025
locomotory behavior GO:0007626 195 0.025
regulation of membrane potential GO:0042391 192 0.024
negative regulation of protein modification process GO:0031400 163 0.024
cellular amino acid metabolic process GO:0006520 103 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
calcium ion transport GO:0006816 159 0.024
microtubule organizing center organization GO:0031023 28 0.024
dna alkylation GO:0006305 43 0.024
trunk segmentation GO:0035290 4 0.023
rhythmic process GO:0048511 174 0.023
forebrain development GO:0030900 302 0.023
histone ubiquitination GO:0016574 10 0.023
kidney development GO:0001822 213 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
cellular homeostasis GO:0019725 240 0.023
determination of heart left right asymmetry GO:0061371 48 0.023
regulation of cell adhesion GO:0030155 154 0.023
regulation of ion transport GO:0043269 215 0.023
regulation of epithelial cell proliferation GO:0050678 141 0.023
regulation of protein transport GO:0051223 163 0.023
protein import GO:0017038 101 0.022
cellular carbohydrate metabolic process GO:0044262 119 0.022
response to alcohol GO:0097305 48 0.022
negative regulation of protein metabolic process GO:0051248 282 0.022
peptidyl amino acid modification GO:0018193 336 0.022
determination of left right symmetry GO:0007368 80 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
lymphocyte proliferation GO:0046651 164 0.022
regulation of transferase activity GO:0051338 263 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
ossification GO:0001503 216 0.021
regulation of cell activation GO:0050865 289 0.021
regulation of transmembrane transport GO:0034762 128 0.021
heterochromatin organization GO:0070828 4 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
compound eye development GO:0048749 1 0.021
cell division GO:0051301 120 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
maintenance of location GO:0051235 89 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
protein localization to organelle GO:0033365 185 0.020
glucose homeostasis GO:0042593 128 0.020
rho protein signal transduction GO:0007266 32 0.020
cell type specific apoptotic process GO:0097285 268 0.020
multicellular organismal signaling GO:0035637 91 0.020
sensory perception of mechanical stimulus GO:0050954 107 0.020
membrane organization GO:0061024 245 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
regulation of cell motility GO:2000145 236 0.019
single organismal cell cell adhesion GO:0016337 131 0.019
negative regulation of cell development GO:0010721 169 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.019
respiratory tube development GO:0030323 167 0.019
camera type eye development GO:0043010 266 0.019
regulation of embryonic development GO:0045995 71 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
stem cell differentiation GO:0048863 268 0.019
nuclear import GO:0051170 95 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
bone development GO:0060348 120 0.019
neuron migration GO:0001764 122 0.019
microtubule based process GO:0007017 236 0.019
cell adhesion GO:0007155 329 0.019
single organism cell adhesion GO:0098602 156 0.019
chemotaxis GO:0006935 247 0.019
digestive system development GO:0055123 200 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
nucleoside metabolic process GO:0009116 246 0.018
tube formation GO:0035148 140 0.018
monosaccharide metabolic process GO:0005996 106 0.018
amine metabolic process GO:0009308 45 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
regulation of secretion by cell GO:1903530 249 0.018
branching morphogenesis of an epithelial tube GO:0048754 159 0.018
multicellular organism growth GO:0035264 161 0.018
cellular chemical homeostasis GO:0055082 215 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
divalent metal ion transport GO:0070838 172 0.018
dna methylation GO:0006306 43 0.018
neuron projection guidance GO:0097485 141 0.018
tissue migration GO:0090130 68 0.018
internal protein amino acid acetylation GO:0006475 42 0.018
morphogenesis of a branching structure GO:0001763 203 0.018
heterocycle catabolic process GO:0046700 280 0.018
germ cell development GO:0007281 185 0.018
Fly
protein autophosphorylation GO:0046777 61 0.018
nucleoside catabolic process GO:0009164 206 0.017
muscle system process GO:0003012 141 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
single fertilization GO:0007338 82 0.017
protein methylation GO:0006479 81 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
protein maturation GO:0051604 176 0.017
histone methylation GO:0016571 71 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
endomembrane system organization GO:0010256 147 0.017
methylation GO:0032259 134 0.017
negative regulation of dna replication GO:0008156 4 0.017
respiratory system development GO:0060541 190 0.017
regulation of circadian sleep wake cycle GO:0042749 3 0.017
regulation of cellular component biogenesis GO:0044087 181 0.016
response to radiation GO:0009314 165 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
purine containing compound catabolic process GO:0072523 213 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
response to reactive oxygen species GO:0000302 56 0.016
mapk cascade GO:0000165 281 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
regulation of cell cycle process GO:0010564 160 0.016
intracellular mrna localization GO:0008298 4 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
cellular response to monosaccharide stimulus GO:0071326 47 0.016
guanosine containing compound metabolic process GO:1901068 144 0.016
transmission of nerve impulse GO:0019226 76 0.016
regulation of cell migration GO:0030334 219 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
cellular glucose homeostasis GO:0001678 52 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
cation homeostasis GO:0055080 212 0.015
calcium ion transmembrane transport GO:0070588 85 0.015
immune effector process GO:0002252 321 0.015
spermatid development GO:0007286 108 0.015
hindbrain development GO:0030902 128 0.015
negative regulation of cell cycle GO:0045786 123 0.015
regulation of cytokine production GO:0001817 266 0.015
negative regulation of cell projection organization GO:0031345 56 0.015
response to organonitrogen compound GO:0010243 246 0.015
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.015
regulation of organ morphogenesis GO:2000027 144 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
cellular response to carbohydrate stimulus GO:0071322 50 0.014
tissue homeostasis GO:0001894 115 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
negative regulation of neuron differentiation GO:0045665 101 0.014
cellular response to oxidative stress GO:0034599 76 0.014
regulation of cell projection organization GO:0031344 206 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
cell fate commitment GO:0045165 210 0.014
establishment or maintenance of cell polarity GO:0007163 86 0.014
histone acetylation GO:0016573 41 0.014
apoptotic signaling pathway GO:0097190 306 0.014
gtp metabolic process GO:0046039 144 0.014
cyclic nucleotide metabolic process GO:0009187 59 0.014
retina development in camera type eye GO:0060041 119 0.014
cellular lipid metabolic process GO:0044255 323 0.014
peptide transport GO:0015833 133 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
regulation of ion transmembrane transporter activity GO:0032412 54 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
regulation of muscle system process GO:0090257 80 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.014
endocrine system development GO:0035270 98 0.014
response to light stimulus GO:0009416 135 0.014
epithelial cell development GO:0002064 159 0.014
Fly
nephron epithelium development GO:0072009 92 0.014
regulation of homeostatic process GO:0032844 182 0.014
negative regulation of synapse assembly GO:0051964 3 0.014
potassium ion transmembrane transport GO:0071805 43 0.014
cellular ion homeostasis GO:0006873 165 0.014
dna metabolic process GO:0006259 303 0.014
negative regulation of epithelial cell proliferation GO:0050680 64 0.014
organic anion transport GO:0015711 137 0.014
regulation of proteolysis GO:0030162 164 0.014
protein acylation GO:0043543 64 0.014
regulation of circadian rhythm GO:0042752 58 0.014
sequestering of calcium ion GO:0051208 18 0.014
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.014
gliogenesis GO:0042063 141 0.014
muscle cell differentiation GO:0042692 261 0.014
plasma membrane organization GO:0007009 90 0.013
limbic system development GO:0021761 72 0.013
negative regulation of neuron projection development GO:0010977 50 0.013
spermatid differentiation GO:0048515 115 0.013
regulation of hydrolase activity GO:0051336 246 0.013
adaptive immune response GO:0002250 155 0.013
regulation of kinase activity GO:0043549 249 0.013
epithelium migration GO:0090132 63 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
neuromuscular process controlling balance GO:0050885 59 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
protein processing GO:0016485 163 0.013
regulation of metal ion transport GO:0010959 106 0.013
positive regulation of nervous system development GO:0051962 221 0.013
peptidyl lysine modification GO:0018205 77 0.013
metal ion homeostasis GO:0055065 189 0.013
neuron neuron synaptic transmission GO:0007270 69 0.013
dna modification GO:0006304 50 0.013
calcium mediated signaling using intracellular calcium source GO:0035584 3 0.013
endothelial cell migration GO:0043542 44 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
cardiac chamber development GO:0003205 108 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
ventral spinal cord development GO:0021517 48 0.013
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.013
cardiac chamber morphogenesis GO:0003206 93 0.013
oocyte differentiation GO:0009994 35 0.013
heart morphogenesis GO:0003007 178 0.012
epithelial cell migration GO:0010631 63 0.012
positive regulation of t cell activation GO:0050870 101 0.012
cellular potassium ion transport GO:0071804 43 0.012
regulation of system process GO:0044057 200 0.012
biomineral tissue development GO:0031214 64 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
circulatory system process GO:0003013 197 0.012
skeletal muscle organ development GO:0060538 163 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
b cell activation GO:0042113 161 0.012
regulation of stem cell proliferation GO:0072091 78 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
epithelial tube formation GO:0072175 130 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
protein localization to membrane GO:0072657 108 0.012
regulation of hormone levels GO:0010817 211 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
learning or memory GO:0007611 148 0.012
neuronal action potential GO:0019228 54 0.012
epidermal growth factor receptor signaling pathway GO:0007173 28 0.012
cellular response to glucose stimulus GO:0071333 45 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
sequestering of metal ion GO:0051238 19 0.012
positive regulation of cell migration GO:0030335 109 0.012
negative regulation of molecular function GO:0044092 258 0.012
positive regulation of ion transport GO:0043270 65 0.012
regulation of carbohydrate metabolic process GO:0006109 75 0.012
positive regulation of dna templated transcription elongation GO:0032786 2 0.012
ear morphogenesis GO:0042471 118 0.012
sensory organ morphogenesis GO:0090596 242 0.011
protein localization to nucleus GO:0034504 121 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
regulation of smoothened signaling pathway GO:0008589 58 0.011
regulation of mapk cascade GO:0043408 248 0.011
peptidyl lysine acetylation GO:0018394 45 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
glial cell differentiation GO:0010001 131 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
heart process GO:0003015 94 0.011
nuclear transport GO:0051169 139 0.011
positive regulation of protein modification process GO:0031401 299 0.011
blood circulation GO:0008015 195 0.011
regulation of chromatin organization GO:1902275 57 0.011
camp metabolic process GO:0046058 40 0.011
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.011
peptide secretion GO:0002790 114 0.011
response to growth factor GO:0070848 198 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
nuclear dna replication GO:0033260 3 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
regulation of neuron projection development GO:0010975 169 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
connective tissue development GO:0061448 179 0.011
cellular response to peptide GO:1901653 92 0.011
cell maturation GO:0048469 127 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
neural tube patterning GO:0021532 43 0.010
multi multicellular organism process GO:0044706 109 0.010
regulation of cellular response to growth factor stimulus GO:0090287 82 0.010
response to inorganic substance GO:0010035 96 0.010
pharynx development GO:0060465 1 0.010
cardiac ventricle development GO:0003231 83 0.010
humoral immune response GO:0006959 57 0.010
tube closure GO:0060606 91 0.010
amide transport GO:0042886 138 0.010
regulation of multi organism process GO:0043900 111 0.010
regulation of gtp catabolic process GO:0033124 113 0.010
regulation of protein complex assembly GO:0043254 83 0.010
wound healing GO:0042060 157 0.010
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
telencephalon development GO:0021537 186 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
regulation of purine nucleotide catabolic process GO:0033121 122 0.010
anatomical structure homeostasis GO:0060249 145 0.010
peptide hormone secretion GO:0030072 109 0.010
cell growth GO:0016049 130 0.010
myotube differentiation GO:0014902 105 0.010
generation of precursor metabolites and energy GO:0006091 103 0.010
protein alkylation GO:0008213 81 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
regulation of protein kinase activity GO:0045859 232 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
response to insulin GO:0032868 100 0.010
sensory perception of sound GO:0007605 97 0.010
stress activated mapk cascade GO:0051403 80 0.010

Scmh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
central nervous system disease DOID:331 0 0.028
neurodegenerative disease DOID:1289 0 0.013