Mus musculus

28 known processes

Scn4a

sodium channel, voltage-gated, type IV, alpha

(Aliases: mH2,Nav1.4)

Scn4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
divalent inorganic cation transport GO:0072511 178 0.615
divalent metal ion transport GO:0070838 172 0.566
regulation of system process GO:0044057 200 0.525
Mouse
calcium ion transport GO:0006816 159 0.465
regulation of ion transport GO:0043269 215 0.426
cation transmembrane transport GO:0098655 266 0.412
cation homeostasis GO:0055080 212 0.338
Mouse
cation transport GO:0006812 399 0.304
blood circulation GO:0008015 195 0.267
Mouse
sequestering of metal ion GO:0051238 19 0.219
transmembrane transport GO:0055085 412 0.213
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.199
cellular ion homeostasis GO:0006873 165 0.197
synaptic transmission GO:0007268 329 0.190
sequestering of calcium ion GO:0051208 18 0.175
nucleobase containing small molecule metabolic process GO:0055086 352 0.171
regulation of circadian sleep wake cycle GO:0042749 3 0.156
nucleoside phosphate metabolic process GO:0006753 338 0.147
cellular metal ion homeostasis GO:0006875 151 0.139
ribonucleoside metabolic process GO:0009119 245 0.139
g protein coupled receptor signaling pathway GO:0007186 243 0.133
mating behavior sex discrimination GO:0048047 1 0.129
purine nucleotide metabolic process GO:0006163 302 0.124
ion transmembrane transport GO:0034220 361 0.120
striated muscle tissue development GO:0014706 293 0.119
cellular divalent inorganic cation homeostasis GO:0072503 127 0.117
metal ion homeostasis GO:0055065 189 0.114
Mouse
ribose phosphate metabolic process GO:0019693 291 0.111
calcium ion transmembrane transport GO:0070588 85 0.110
regulation of ion homeostasis GO:2000021 64 0.107
Mouse
cellular amine metabolic process GO:0044106 44 0.104
regulation of secretion by cell GO:1903530 249 0.103
muscle system process GO:0003012 141 0.098
Mouse
muscle tissue development GO:0060537 308 0.097
cellular nitrogen compound catabolic process GO:0044270 280 0.095
regulation of metal ion transport GO:0010959 106 0.094
nitrogen compound transport GO:0071705 271 0.094
Rat
cellular amino acid metabolic process GO:0006520 103 0.091
heterocycle catabolic process GO:0046700 280 0.087
aromatic compound catabolic process GO:0019439 286 0.086
peptidyl amino acid modification GO:0018193 336 0.085
regulation of response to wounding GO:1903034 189 0.084
response to inactivity GO:0014854 4 0.082
action potential GO:0001508 78 0.079
Mouse
cellular chemical homeostasis GO:0055082 215 0.075
organophosphate catabolic process GO:0046434 232 0.071
regulation of cellular amine metabolic process GO:0033238 20 0.070
atp metabolic process GO:0046034 75 0.070
detection of stimulus GO:0051606 84 0.070
ossification GO:0001503 216 0.068
ribonucleotide metabolic process GO:0009259 291 0.068
camera type eye development GO:0043010 266 0.068
glycosyl compound metabolic process GO:1901657 246 0.067
purine containing compound metabolic process GO:0072521 311 0.066
purine ribonucleotide metabolic process GO:0009150 290 0.065
learning or memory GO:0007611 148 0.064
bone development GO:0060348 120 0.064
organ growth GO:0035265 117 0.063
sensory perception GO:0007600 245 0.061
Mouse
purine nucleoside metabolic process GO:0042278 241 0.061
gland development GO:0048732 330 0.060
regulation of protein localization GO:0032880 231 0.060
muscle cell differentiation GO:0042692 261 0.060
nucleoside metabolic process GO:0009116 246 0.060
multicellular organismal signaling GO:0035637 91 0.059
Mouse
negative regulation of cell proliferation GO:0008285 296 0.059
regulation of membrane potential GO:0042391 192 0.058
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.058
heart morphogenesis GO:0003007 178 0.057
skeletal muscle organ development GO:0060538 163 0.057
regulation of nucleotide metabolic process GO:0006140 169 0.057
regulation of secretion GO:0051046 274 0.056
nucleotide metabolic process GO:0009117 332 0.056
epithelial tube morphogenesis GO:0060562 303 0.056
gene silencing GO:0016458 38 0.055
calcium mediated signaling GO:0019722 46 0.055
cellular homeostasis GO:0019725 240 0.054
cardiac ventricle development GO:0003231 83 0.054
Mouse
developmental maturation GO:0021700 193 0.053
ribonucleoside catabolic process GO:0042454 206 0.053
circulatory system process GO:0003013 197 0.053
Mouse
regulation of calcium ion transport GO:0051924 69 0.053
maintenance of location GO:0051235 89 0.053
regulation of cellular catabolic process GO:0031329 242 0.053
muscle cell development GO:0055001 133 0.051
regionalization GO:0003002 337 0.051
divalent inorganic cation homeostasis GO:0072507 138 0.050
epithelial cell proliferation GO:0050673 174 0.049
muscle fiber development GO:0048747 76 0.049
purine ribonucleoside metabolic process GO:0046128 241 0.049
organonitrogen compound catabolic process GO:1901565 264 0.049
cytosolic calcium ion homeostasis GO:0051480 70 0.048
inorganic ion transmembrane transport GO:0098660 234 0.047
skeletal muscle fiber development GO:0048741 58 0.047
calcium ion homeostasis GO:0055074 127 0.046
purine nucleoside triphosphate metabolic process GO:0009144 226 0.046
regulation of epithelial cell proliferation GO:0050678 141 0.046
negative regulation of homeostatic process GO:0032845 71 0.046
organic cyclic compound catabolic process GO:1901361 295 0.046
endomembrane system organization GO:0010256 147 0.046
negative regulation of cell development GO:0010721 169 0.046
regulation of transmembrane transport GO:0034762 128 0.045
skeletal system development GO:0001501 356 0.044
regulation of purine nucleotide metabolic process GO:1900542 169 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.044
muscle contraction GO:0006936 101 0.044
Mouse
cellular ketone metabolic process GO:0042180 84 0.044
cytosolic calcium ion transport GO:0060401 48 0.044
cell type specific apoptotic process GO:0097285 268 0.044
Mouse
tube formation GO:0035148 140 0.044
regulation of cellular ketone metabolic process GO:0010565 66 0.043
response to nutrient levels GO:0031667 109 0.043
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.043
regulation of defense response GO:0031347 233 0.042
regulation of neuron death GO:1901214 134 0.042
purine ribonucleotide catabolic process GO:0009154 208 0.041
positive regulation of protein modification process GO:0031401 299 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.041
synapse organization GO:0050808 125 0.040
neuromuscular process GO:0050905 99 0.040
Mouse
regulation of protein kinase activity GO:0045859 232 0.039
apoptotic signaling pathway GO:0097190 306 0.039
Mouse
inflammatory response GO:0006954 244 0.039
Mouse
axonogenesis GO:0007409 274 0.039
stem cell differentiation GO:0048863 268 0.039
positive regulation of vasoconstriction GO:0045907 4 0.039
circadian rhythm GO:0007623 114 0.038
cellular response to abiotic stimulus GO:0071214 56 0.038
Mouse
release of sequestered calcium ion into cytosol GO:0051209 42 0.038
associative learning GO:0008306 61 0.038
ribonucleotide catabolic process GO:0009261 208 0.037
regulation of homeostatic process GO:0032844 182 0.037
Mouse
neurotransmitter transport GO:0006836 76 0.037
amine metabolic process GO:0009308 45 0.036
regulation of intracellular transport GO:0032386 159 0.036
embryonic epithelial tube formation GO:0001838 130 0.035
neuron migration GO:0001764 122 0.035
nucleotide catabolic process GO:0009166 217 0.035
rhythmic process GO:0048511 174 0.035
organonitrogen compound biosynthetic process GO:1901566 192 0.035
multicellular organismal homeostasis GO:0048871 164 0.035
positive regulation of apoptotic process GO:0043065 217 0.035
germ cell development GO:0007281 185 0.034
epidermis development GO:0008544 187 0.034
posttranscriptional regulation of gene expression GO:0010608 155 0.034
male gamete generation GO:0048232 285 0.034
positive regulation of ion transport GO:0043270 65 0.034
negative regulation of nervous system development GO:0051961 156 0.034
calcium ion transport into cytosol GO:0060402 48 0.034
amino acid transport GO:0006865 61 0.034
hemangioblast cell differentiation GO:0060217 1 0.034
extracellular matrix organization GO:0030198 147 0.034
cytoplasmic transport GO:0016482 234 0.034
regulation of apoptotic signaling pathway GO:2001233 197 0.034
multicellular organism growth GO:0035264 161 0.033
cognition GO:0050890 149 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
nucleoside monophosphate metabolic process GO:0009123 85 0.033
striated muscle cell development GO:0055002 125 0.033
membrane organization GO:0061024 245 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
exocytosis GO:0006887 121 0.032
negative regulation of inflammatory response GO:0050728 61 0.032
purine containing compound catabolic process GO:0072523 213 0.032
rna interference GO:0016246 2 0.032
detection of light stimulus GO:0009583 25 0.031
regulation of cellular component biogenesis GO:0044087 181 0.031
macromolecule methylation GO:0043414 120 0.031
ribonucleoside triphosphate metabolic process GO:0009199 220 0.031
detection of abiotic stimulus GO:0009582 60 0.031
purine nucleoside catabolic process GO:0006152 205 0.031
carbohydrate derivative catabolic process GO:1901136 231 0.031
positive regulation of atpase activity GO:0032781 3 0.031
regulation of cell activation GO:0050865 289 0.031
negative regulation of defense response GO:0031348 77 0.030
regulation of tumor necrosis factor production GO:0032680 49 0.030
cell growth GO:0016049 130 0.030
cellular response to hormone stimulus GO:0032870 150 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
spermatogenesis GO:0007283 284 0.029
myeloid leukocyte differentiation GO:0002573 119 0.029
small gtpase mediated signal transduction GO:0007264 97 0.029
ribonucleoside monophosphate metabolic process GO:0009161 80 0.029
stem cell development GO:0048864 219 0.029
chemotaxis GO:0006935 247 0.029
leukocyte differentiation GO:0002521 342 0.029
regulation of circadian rhythm GO:0042752 58 0.029
segmentation GO:0035282 93 0.029
lymphocyte differentiation GO:0030098 242 0.028
gene silencing by rna GO:0031047 19 0.028
regulation of renal sodium excretion GO:0035813 3 0.028
intermediate filament cytoskeleton organization GO:0045104 26 0.028
conditioned taste aversion GO:0001661 4 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
hormone metabolic process GO:0042445 86 0.028
molting cycle GO:0042303 90 0.027
striated muscle contraction GO:0006941 45 0.027
Mouse
negative regulation of osteoblast differentiation GO:0045668 30 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.027
regulation of reproductive process GO:2000241 66 0.027
positive regulation of cellular catabolic process GO:0031331 148 0.027
positive regulation of synaptic plasticity GO:0031915 4 0.027
positive regulation of nucleotide catabolic process GO:0030813 88 0.026
hair follicle development GO:0001942 85 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
immune effector process GO:0002252 321 0.026
anion transport GO:0006820 177 0.026
cardiac muscle cell contraction GO:0086003 7 0.026
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.026
regulation of inflammatory response GO:0050727 147 0.026
renal sodium excretion GO:0035812 3 0.026
learning GO:0007612 98 0.026
oviduct development GO:0060066 3 0.026
multicellular organismal response to stress GO:0033555 62 0.025
Mouse
cellular response to lipid GO:0071396 145 0.025
central nervous system neuron development GO:0021954 67 0.025
purine nucleotide catabolic process GO:0006195 211 0.025
regulation of purine nucleotide catabolic process GO:0033121 122 0.025
regulation of synaptic plasticity GO:0048167 87 0.025
neuron apoptotic process GO:0051402 142 0.025
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
ras protein signal transduction GO:0007265 77 0.025
extrinsic apoptotic signaling pathway GO:0097191 126 0.025
response to radiation GO:0009314 165 0.025
cytokine production GO:0001816 319 0.024
retina development in camera type eye GO:0060041 119 0.024
protein secretion GO:0009306 111 0.024
neural tube development GO:0021915 160 0.024
regulation of heart contraction GO:0008016 77 0.024
Mouse
rho protein signal transduction GO:0007266 32 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
detection of external stimulus GO:0009581 61 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
response to molecule of bacterial origin GO:0002237 143 0.024
regulation of calcium ion transport into cytosol GO:0010522 31 0.023
neural tube formation GO:0001841 108 0.023
regulation of neurotransmitter levels GO:0001505 87 0.023
myotube cell development GO:0014904 60 0.023
epithelial cell morphogenesis GO:0003382 41 0.023
response to organonitrogen compound GO:0010243 246 0.023
positive regulation of epithelial cell proliferation GO:0050679 68 0.023
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.023
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.023
regulation of nucleotide catabolic process GO:0030811 122 0.023
negative regulation of protein modification process GO:0031400 163 0.023
cardiac muscle contraction GO:0060048 32 0.023
Mouse
ventricular cardiac muscle tissue development GO:0003229 38 0.023
neuron projection extension GO:1990138 64 0.023
regulation of heart rate GO:0002027 36 0.023
Mouse
purine nucleoside monophosphate metabolic process GO:0009126 81 0.023
mesoderm development GO:0007498 100 0.022
sensory perception of pain GO:0019233 47 0.022
Mouse
glycosyl compound catabolic process GO:1901658 206 0.022
transmission of nerve impulse GO:0019226 76 0.022
Mouse
organic hydroxy compound transport GO:0015850 93 0.022
Rat
cellular lipid metabolic process GO:0044255 323 0.022
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.022
negative regulation of apoptotic signaling pathway GO:2001234 104 0.022
adult behavior GO:0030534 135 0.022
Mouse
tumor necrosis factor production GO:0032640 50 0.022
response to oxygen levels GO:0070482 62 0.022
sulfur compound metabolic process GO:0006790 100 0.022
hematopoietic progenitor cell differentiation GO:0002244 143 0.022
astrocyte fate commitment GO:0060018 4 0.022
neural crest cell migration GO:0001755 32 0.021
mitochondrion distribution GO:0048311 4 0.021
detection of molecule of bacterial origin GO:0032490 2 0.021
positive regulation of growth GO:0045927 104 0.021
regulation of organelle organization GO:0033043 289 0.021
developmental growth involved in morphogenesis GO:0060560 138 0.021
visual perception GO:0007601 52 0.021
regulation of hormone levels GO:0010817 211 0.021
response to extracellular stimulus GO:0009991 127 0.021
regulation of leukocyte proliferation GO:0070663 121 0.021
mesenchymal cell differentiation GO:0048762 107 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.020
extracellular structure organization GO:0043062 148 0.020
polarity specification of proximal distal axis GO:0010085 2 0.020
sensory organ morphogenesis GO:0090596 242 0.020
intracellular distribution of mitochondria GO:0048312 1 0.020
regulation of blood pressure GO:0008217 93 0.020
sleep GO:0030431 7 0.020
response to metal ion GO:0010038 47 0.020
regulation of ion transmembrane transport GO:0034765 119 0.020
second messenger mediated signaling GO:0019932 73 0.020
sclerotome development GO:0061056 4 0.020
gtp catabolic process GO:0006184 143 0.020
tube closure GO:0060606 91 0.020
cellular response to inorganic substance GO:0071241 37 0.020
myotube differentiation GO:0014902 105 0.020
neurotransmitter secretion GO:0007269 62 0.020
regulation of blood circulation GO:1903522 93 0.020
Mouse
covalent chromatin modification GO:0016569 163 0.020
cell cycle switching GO:0060184 1 0.020
auditory receptor cell fate specification GO:0042667 1 0.020
angiogenesis GO:0001525 201 0.020
positive regulation of nucleotide metabolic process GO:0045981 114 0.020
positive regulation of cell development GO:0010720 237 0.019
posttranscriptional gene silencing GO:0016441 10 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
regulation of exit from mitosis GO:0007096 1 0.019
regulation of chromosome organization GO:0033044 83 0.019
negative regulation of ossification GO:0030279 49 0.019
negative regulation of molecular function GO:0044092 258 0.019
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.019
dendrite development GO:0016358 115 0.019
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
ensheathment of neurons GO:0007272 76 0.019
response to lipopolysaccharide GO:0032496 128 0.019
lipid biosynthetic process GO:0008610 179 0.019
skin development GO:0043588 220 0.019
sperm motility GO:0030317 47 0.019
regulation of kinase activity GO:0043549 249 0.018
glycoprotein metabolic process GO:0009100 116 0.018
positive regulation of cell growth GO:0030307 33 0.018
retina morphogenesis in camera type eye GO:0060042 45 0.018
posttranscriptional gene silencing by rna GO:0035194 10 0.018
oxidation reduction process GO:0055114 342 0.018
regulation of hydrolase activity GO:0051336 246 0.018
multi multicellular organism process GO:0044706 109 0.018
sensory system development GO:0048880 3 0.018
histone modification GO:0016570 159 0.018
negative regulation of neuron apoptotic process GO:0043524 92 0.018
positive regulation of cell death GO:0010942 224 0.018
cellular response to metal ion GO:0071248 31 0.018
nucleoside catabolic process GO:0009164 206 0.018
organelle localization GO:0051640 179 0.017
determination of left right symmetry GO:0007368 80 0.017
regulation of thyroid hormone generation GO:2000609 4 0.017
heart process GO:0003015 94 0.017
Mouse
cerebellum development GO:0021549 77 0.017
regulation of striated muscle cell differentiation GO:0051153 81 0.017
neural retina development GO:0003407 41 0.017
cell maturation GO:0048469 127 0.017
peptidyl serine modification GO:0018209 83 0.017
developmental cell growth GO:0048588 84 0.017
feeding behavior GO:0007631 62 0.017
water homeostasis GO:0030104 27 0.017
regulation of interleukin 8 secretion GO:2000482 2 0.017
epithelial tube formation GO:0072175 130 0.017
positive regulation of kinase activity GO:0033674 155 0.017
regulation of exocytosis GO:0017157 61 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
forebrain development GO:0030900 302 0.017
inner ear morphogenesis GO:0042472 101 0.017
dephosphorylation GO:0016311 129 0.017
atp catabolic process GO:0006200 55 0.017
monoamine transport GO:0015844 33 0.017
cell adhesion GO:0007155 329 0.017
chromatin modification GO:0016568 187 0.017
organelle fission GO:0048285 170 0.017
mapk cascade GO:0000165 281 0.017
notch signaling pathway GO:0007219 71 0.017
exocrine system development GO:0035272 45 0.017
positive regulation of atp catabolic process GO:1903291 3 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.016
regulation of transferase activity GO:0051338 263 0.016
digestive system development GO:0055123 200 0.016
methylation GO:0032259 134 0.016
cellular response to calcium ion GO:0071277 14 0.016
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
morphogenesis of a branching epithelium GO:0061138 193 0.016
hair cycle GO:0042633 90 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
regulation of neurotransmitter secretion GO:0046928 29 0.016
negative regulation of immune system process GO:0002683 209 0.016
myoblast differentiation GO:0045445 52 0.016
negative regulation of wnt signaling pathway GO:0030178 73 0.016
regulation of cell size GO:0008361 72 0.016
guanosine containing compound metabolic process GO:1901068 144 0.016
rac protein signal transduction GO:0016601 13 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
regulation of systemic arterial blood pressure GO:0003073 61 0.016
gliogenesis GO:0042063 141 0.016
heart contraction GO:0060047 93 0.016
Mouse
regulation of feeding behavior GO:0060259 3 0.016
cardiac chamber morphogenesis GO:0003206 93 0.015
oocyte construction GO:0007308 2 0.015
visceral serous pericardium development GO:0061032 2 0.015
neuronal action potential GO:0019228 54 0.015
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
regulation of atp metabolic process GO:1903578 17 0.015
mitochondrion organization GO:0007005 134 0.015
type b pancreatic cell proliferation GO:0044342 10 0.015
mitotic cytokinesis GO:0000281 4 0.015
response to light stimulus GO:0009416 135 0.015
olfactory learning GO:0008355 2 0.015
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.015
regulation of cell growth GO:0001558 91 0.015
memory GO:0007613 58 0.015
cervix development GO:0060067 2 0.015
cellular protein complex assembly GO:0043623 116 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
regulation of muscle contraction GO:0006937 49 0.015
Mouse
pancreatic a cell fate commitment GO:0003326 2 0.015
cellular response to nutrient levels GO:0031669 64 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
peptidyl lysine modification GO:0018205 77 0.015
placenta development GO:0001890 140 0.015
regulation of lymphocyte proliferation GO:0050670 117 0.014
chromatin organization GO:0006325 206 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
response to growth factor GO:0070848 198 0.014
neural tube closure GO:0001843 90 0.014
positive regulation of cell activation GO:0050867 158 0.014
response to hypoxia GO:0001666 58 0.014
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.014
regulation of anatomical structure size GO:0090066 178 0.014
cardiac muscle tissue development GO:0048738 130 0.014
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.014
acetate ester transport GO:1901374 2 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
blastocyst development GO:0001824 80 0.014
male courtship behavior GO:0008049 2 0.014
cellular response to steroid hormone stimulus GO:0071383 33 0.014
ribonucleoside monophosphate catabolic process GO:0009158 57 0.014
regulation of muscle system process GO:0090257 80 0.014
Mouse
cellular response to external stimulus GO:0071496 88 0.014
response to muscle inactivity GO:0014870 4 0.014
cell chemotaxis GO:0060326 81 0.014
regulation of cell motility GO:2000145 236 0.014
regulation of retina development in camera type eye GO:1902866 3 0.014
salivary gland development GO:0007431 37 0.014
regulation of interleukin 1 alpha production GO:0032650 4 0.014
ear development GO:0043583 200 0.014
regulation of rho protein signal transduction GO:0035023 71 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
mrna metabolic process GO:0016071 84 0.014
cardiac muscle tissue morphogenesis GO:0055008 44 0.014
regulation of neuron differentiation GO:0045664 281 0.014
purine nucleoside monophosphate catabolic process GO:0009128 58 0.014
glucose homeostasis GO:0042593 128 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
homeostasis of number of cells GO:0048872 210 0.014
regulation of keratinocyte proliferation GO:0010837 15 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
digestive tract development GO:0048565 190 0.014
renal system process GO:0003014 48 0.013
embryonic placenta development GO:0001892 98 0.013
negative regulation of neuron projection development GO:0010977 50 0.013
rna processing GO:0006396 105 0.013
lymphocyte proliferation GO:0046651 164 0.013
regulation of cellular response to stress GO:0080135 159 0.013
cerebral cortex development GO:0021987 86 0.013
regulation of cytokine production GO:0001817 266 0.013
regulation of actin filament based process GO:0032970 99 0.013
Mouse
paramesonephric duct development GO:0061205 3 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
dna metabolic process GO:0006259 303 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
tachykinin receptor signaling pathway GO:0007217 1 0.013
regulation of proteolysis GO:0030162 164 0.013
tendon formation GO:0035992 4 0.013
norepinephrine transport GO:0015874 2 0.013
regulation of multi organism process GO:0043900 111 0.013
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
somite development GO:0061053 81 0.013
neuron death GO:0070997 154 0.013
Mouse
defense response to other organism GO:0098542 197 0.013
stem cell maintenance GO:0019827 130 0.013
skeletal system morphogenesis GO:0048705 203 0.013
regulation of transporter activity GO:0032409 57 0.013
regulation of neural retina development GO:0061074 3 0.013
regulation of neuron projection development GO:0010975 169 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
specification of organ identity GO:0010092 30 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
central nervous system morphogenesis GO:0021551 2 0.013
positive regulation of heart rate GO:0010460 10 0.013
determination of heart left right asymmetry GO:0061371 48 0.013
regulation of translation GO:0006417 71 0.013
amide transport GO:0042886 138 0.013
sensory perception of light stimulus GO:0050953 54 0.012
positive regulation of blood circulation GO:1903524 22 0.012
artery development GO:0060840 53 0.012
regulation of ion transmembrane transporter activity GO:0032412 54 0.012
regulation of mrna metabolic process GO:1903311 43 0.012
spermatid differentiation GO:0048515 115 0.012
regulation of chromatin organization GO:1902275 57 0.012
myelination GO:0042552 74 0.012
protein localization to membrane GO:0072657 108 0.012
negative regulation of gene silencing GO:0060969 2 0.012
response to organic cyclic compound GO:0014070 198 0.012
Mouse
positive regulation of organelle organization GO:0010638 128 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
pancreatic pp cell differentiation GO:0003312 2 0.012

Scn4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.105
disease of anatomical entity DOID:7 0 0.105
nervous system disease DOID:863 0 0.105
eye and adnexa disease DOID:1492 0 0.045
eye disease DOID:5614 0 0.040
disease of metabolism DOID:0014667 0 0.026
acquired metabolic disease DOID:0060158 0 0.026