Mus musculus

29 known processes

Scn7a

sodium channel, voltage-gated, type VII, alpha

(Aliases: NaG,Scn6a,AI642000,Nav2,Nav2.3,Nax,1110034K09Rik)

Scn7a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
circulatory system process GO:0003013 197 0.677
Mouse
regulation of ion transport GO:0043269 215 0.594
Zebrafish Mouse
blood circulation GO:0008015 195 0.497
Mouse
vascular process in circulatory system GO:0003018 62 0.453
muscle system process GO:0003012 141 0.368
Mouse
cation transport GO:0006812 399 0.358
regulation of system process GO:0044057 200 0.316
Mouse
ion transmembrane transport GO:0034220 361 0.306
regulation of muscle system process GO:0090257 80 0.265
Mouse
regulation of secretion by cell GO:1903530 249 0.255
regulation of tube size GO:0035150 57 0.248
cell adhesion GO:0007155 329 0.239
rhodopsin mediated signaling pathway GO:0016056 4 0.235
regulation of cellular amine metabolic process GO:0033238 20 0.234
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.219
regulation of blood vessel size GO:0050880 56 0.184
muscle cell differentiation GO:0042692 261 0.170
regulation of blood pressure GO:0008217 93 0.169
sensory perception GO:0007600 245 0.167
Mouse
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.163
muscle contraction GO:0006936 101 0.160
Mouse
regulation of blood circulation GO:1903522 93 0.158
Mouse
regulation of anatomical structure size GO:0090066 178 0.157
cell cell signaling involved in lung development GO:0060495 1 0.156
axonogenesis GO:0007409 274 0.148
acetylcholine transport GO:0015870 2 0.147
g protein coupled receptor signaling pathway GO:0007186 243 0.144
regulation of secretion GO:0051046 274 0.140
angiogenesis GO:0001525 201 0.140
response to lipopolysaccharide GO:0032496 128 0.139
cellular response to cytokine stimulus GO:0071345 189 0.128
anatomical structure homeostasis GO:0060249 145 0.127
regulation of cellular amino acid metabolic process GO:0006521 5 0.124
blood vessel morphogenesis GO:0048514 285 0.119
regulation of body fluid levels GO:0050878 162 0.117
kidney development GO:0001822 213 0.116
axon guidance GO:0007411 141 0.116
neuron migration GO:0001764 122 0.115
sensory perception of sound GO:0007605 97 0.112
Mouse
divalent metal ion transport GO:0070838 172 0.110
regulation of defense response GO:0031347 233 0.109
regulation of cell activation GO:0050865 289 0.109
synapse organization GO:0050808 125 0.109
amine metabolic process GO:0009308 45 0.108
cellular amine metabolic process GO:0044106 44 0.108
regulation of protein kinase activity GO:0045859 232 0.108
branching morphogenesis of an epithelial tube GO:0048754 159 0.108
regulation of cell adhesion GO:0030155 154 0.105
transmembrane transport GO:0055085 412 0.103
muscle cell development GO:0055001 133 0.102
positive regulation of secretion by cell GO:1903532 114 0.101
cation transmembrane transport GO:0098655 266 0.100
striated muscle cell development GO:0055002 125 0.100
regulation of angiogenesis GO:0045765 81 0.099
morphogenesis of embryonic epithelium GO:0016331 159 0.097
developmental maturation GO:0021700 193 0.096
immune effector process GO:0002252 321 0.095
heart process GO:0003015 94 0.095
Mouse
regulation of lymphocyte activation GO:0051249 240 0.094
regulation of apoptotic signaling pathway GO:2001233 197 0.093
apoptotic signaling pathway GO:0097190 306 0.092
Mouse
response to radiation GO:0009314 165 0.092
cellular ketone metabolic process GO:0042180 84 0.091
physiological cardiac muscle hypertrophy GO:0003301 3 0.088
negative regulation of phosphate metabolic process GO:0045936 184 0.088
branching involved in salivary gland morphogenesis GO:0060445 26 0.088
cellular homeostasis GO:0019725 240 0.088
positive regulation of protein phosphorylation GO:0001934 242 0.087
small gtpase mediated signal transduction GO:0007264 97 0.086
renal system development GO:0072001 225 0.086
smooth muscle contraction GO:0006939 44 0.086
detection of stimulus GO:0051606 84 0.084
sensory perception of mechanical stimulus GO:0050954 107 0.082
Mouse
adaptive immune response GO:0002250 155 0.081
regulation of vasculature development GO:1901342 88 0.081
regulation of homeostatic process GO:0032844 182 0.080
Mouse
regulation of protein secretion GO:0050708 82 0.078
regulation of membrane potential GO:0042391 192 0.077
Zebrafish Mouse
regulation of protein localization GO:0032880 231 0.077
sympathetic neuron projection guidance GO:0097491 4 0.076
negative regulation of intracellular signal transduction GO:1902532 167 0.075
trunk neural crest cell migration GO:0036484 4 0.075
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.073
camera type eye development GO:0043010 266 0.072
acetate ester transport GO:1901374 2 0.072
regulation of cellular ketone metabolic process GO:0010565 66 0.071
activation of immune response GO:0002253 138 0.069
leukocyte proliferation GO:0070661 172 0.069
inflammatory response GO:0006954 244 0.069
Mouse
lymphocyte differentiation GO:0030098 242 0.069
regulation of cytokine secretion GO:0050707 61 0.068
protein kinase b signaling GO:0043491 74 0.068
regulation of cell projection organization GO:0031344 206 0.068
muscle adaptation GO:0043500 39 0.067
regulation of cell growth involved in cardiac muscle cell development GO:0061050 3 0.067
gland development GO:0048732 330 0.066
ventral trunk neural crest cell migration GO:0036486 4 0.065
negative regulation of immune system process GO:0002683 209 0.065
cellular metal ion homeostasis GO:0006875 151 0.065
macromolecule catabolic process GO:0009057 281 0.064
production of molecular mediator of immune response GO:0002440 103 0.063
actin cytoskeleton organization GO:0030036 220 0.063
second messenger mediated signaling GO:0019932 73 0.062
cytoplasmic transport GO:0016482 234 0.062
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.062
endocytosis GO:0006897 168 0.062
ear morphogenesis GO:0042471 118 0.062
endocrine process GO:0050886 39 0.061
immune response activating signal transduction GO:0002757 116 0.060
actomyosin structure organization GO:0031032 56 0.060
organic cyclic compound catabolic process GO:1901361 295 0.059
negative regulation of cellular component organization GO:0051129 194 0.059
stem cell differentiation GO:0048863 268 0.059
cell growth involved in cardiac muscle cell development GO:0061049 3 0.059
sympathetic neuron projection extension GO:0097490 4 0.058
cellular chemical homeostasis GO:0055082 215 0.058
epithelial tube morphogenesis GO:0060562 303 0.058
positive regulation of secretion GO:0051047 130 0.057
regulation of hydrolase activity GO:0051336 246 0.057
vasoconstriction GO:0042310 27 0.057
t cell activation GO:0042110 289 0.056
response to organic cyclic compound GO:0014070 198 0.056
Mouse
negative regulation of molecular function GO:0044092 258 0.055
inner ear morphogenesis GO:0042472 101 0.055
leukocyte differentiation GO:0002521 342 0.055
cellular response to oxidative stress GO:0034599 76 0.055
morphogenesis of a branching structure GO:0001763 203 0.055
cell substrate adhesion GO:0031589 130 0.054
regulation of neuron differentiation GO:0045664 281 0.054
blood coagulation GO:0007596 76 0.054
positive regulation of nervous system development GO:0051962 221 0.053
adult behavior GO:0030534 135 0.053
Mouse
cellular amino acid metabolic process GO:0006520 103 0.052
regulation of neuron death GO:1901214 134 0.052
metal ion homeostasis GO:0055065 189 0.052
ameboidal type cell migration GO:0001667 128 0.052
regulation of voltage gated calcium channel activity GO:1901385 4 0.051
regulation of neuron apoptotic process GO:0043523 122 0.051
dendrite development GO:0016358 115 0.050
fat cell differentiation GO:0045444 160 0.050
cytokine production GO:0001816 319 0.050
regulation of inflammatory response GO:0050727 147 0.050
morphogenesis of a branching epithelium GO:0061138 193 0.049
innate immune response GO:0045087 157 0.049
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.049
regulation of mapk cascade GO:0043408 248 0.049
nephron development GO:0072006 109 0.049
negative regulation of cell proliferation GO:0008285 296 0.048
carbohydrate derivative biosynthetic process GO:1901137 183 0.048
protein oligomerization GO:0051259 67 0.048
regulation of establishment of protein localization GO:0070201 181 0.048
regulation of kinase activity GO:0043549 249 0.048
rhythmic process GO:0048511 174 0.048
organ regeneration GO:0031100 2 0.047
striated muscle tissue development GO:0014706 293 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
regulation of response to wounding GO:1903034 189 0.046
positive regulation of phospholipase c activity GO:0010863 2 0.046
negative regulation of cellular amine metabolic process GO:0033239 1 0.046
ras protein signal transduction GO:0007265 77 0.046
positive regulation of protein modification process GO:0031401 299 0.045
heterocycle catabolic process GO:0046700 280 0.045
regulation of systemic arterial blood pressure GO:0003073 61 0.045
renal system process GO:0003014 48 0.044
germ cell development GO:0007281 185 0.044
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.044
muscle hypertrophy GO:0014896 24 0.044
synaptic transmission GO:0007268 329 0.044
stem cell development GO:0048864 219 0.044
chorionic trophoblast cell proliferation GO:0097360 1 0.044
positive regulation of mapk cascade GO:0043410 170 0.044
regulation of leukocyte proliferation GO:0070663 121 0.043
regulation of ion transmembrane transporter activity GO:0032412 54 0.043
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.043
cytosolic calcium ion homeostasis GO:0051480 70 0.043
response to organonitrogen compound GO:0010243 246 0.042
regulation of nucleotide catabolic process GO:0030811 122 0.042
regulation of cellular component biogenesis GO:0044087 181 0.042
cellular nitrogen compound catabolic process GO:0044270 280 0.042
cellular response to lipid GO:0071396 145 0.042
regulation of cell growth GO:0001558 91 0.042
regulation of organelle organization GO:0033043 289 0.041
relaxation of vascular smooth muscle GO:0060087 7 0.041
chemotaxis GO:0006935 247 0.041
negative regulation of cell development GO:0010721 169 0.041
peptidyl tyrosine modification GO:0018212 145 0.041
ear development GO:0043583 200 0.041
regulation of transferase activity GO:0051338 263 0.041
cellular response to external stimulus GO:0071496 88 0.041
peptidyl amino acid modification GO:0018193 336 0.040
spermatid development GO:0007286 108 0.039
regulation of lymphocyte proliferation GO:0050670 117 0.039
regionalization GO:0003002 337 0.039
negative regulation of cell adhesion GO:0007162 45 0.039
detection of abiotic stimulus GO:0009582 60 0.039
regulation of ion transmembrane transport GO:0034765 119 0.039
Zebrafish Mouse
muscle tissue development GO:0060537 308 0.038
protein catabolic process GO:0030163 221 0.038
response to alcohol GO:0097305 48 0.038
cytokine mediated signaling pathway GO:0019221 115 0.038
lung development GO:0030324 164 0.038
response to molecule of bacterial origin GO:0002237 143 0.038
sensory perception of pain GO:0019233 47 0.038
Mouse
cation homeostasis GO:0055080 212 0.038
regulation of transmembrane transport GO:0034762 128 0.037
Zebrafish Mouse
alpha beta t cell activation GO:0046631 91 0.037
t cell differentiation GO:0030217 174 0.037
lymphocyte proliferation GO:0046651 164 0.037
rho protein signal transduction GO:0007266 32 0.037
cell maturation GO:0048469 127 0.037
regulation of protein transport GO:0051223 163 0.037
respiratory system development GO:0060541 190 0.037
negative regulation of phosphorus metabolic process GO:0010563 184 0.037
cellular response to growth factor stimulus GO:0071363 197 0.037
neuronal action potential GO:0019228 54 0.036
Zebrafish Mouse
physiological muscle hypertrophy GO:0003298 3 0.036
positive regulation of cell adhesion GO:0045785 80 0.036
wound healing GO:0042060 157 0.036
cellular ion homeostasis GO:0006873 165 0.036
calcium ion transport GO:0006816 159 0.036
maintenance of location GO:0051235 89 0.036
semicircular canal fusion GO:0060879 1 0.036
regulation of purine nucleotide metabolic process GO:1900542 169 0.036
cell growth GO:0016049 130 0.036
regulation of smooth muscle contraction GO:0006940 22 0.036
protein autoprocessing GO:0016540 2 0.035
peptidyl tyrosine phosphorylation GO:0018108 143 0.035
regulation of intracellular transport GO:0032386 159 0.035
cellular response to abiotic stimulus GO:0071214 56 0.035
Mouse
positive regulation of transferase activity GO:0051347 167 0.035
calcium ion homeostasis GO:0055074 127 0.035
receptor mediated endocytosis GO:0006898 51 0.035
glomerulus development GO:0032835 40 0.034
negative regulation of protein metabolic process GO:0051248 282 0.034
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.034
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.033
detection of external stimulus GO:0009581 61 0.033
skeletal system development GO:0001501 356 0.033
regulation of epithelial cell proliferation GO:0050678 141 0.033
regulation of metal ion transport GO:0010959 106 0.033
ribose phosphate metabolic process GO:0019693 291 0.033
protein import into nucleus GO:0006606 95 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
negative regulation of angiogenesis GO:0016525 25 0.032
neural tube formation GO:0001841 108 0.032
cell type specific apoptotic process GO:0097285 268 0.032
Mouse
learning or memory GO:0007611 148 0.032
divalent inorganic cation transport GO:0072511 178 0.032
regulation of protein kinase b signaling GO:0051896 56 0.032
negative regulation of hydrolase activity GO:0051346 71 0.031
purine nucleotide metabolic process GO:0006163 302 0.031
response to hypoxia GO:0001666 58 0.031
lipid localization GO:0010876 126 0.031
response to acid chemical GO:0001101 111 0.031
protein secretion GO:0009306 111 0.031
epithelial cell migration GO:0010631 63 0.031
single organism cell adhesion GO:0098602 156 0.031
heart contraction GO:0060047 93 0.031
Mouse
negative regulation of vasculature development GO:1901343 26 0.031
cellular response to hormone stimulus GO:0032870 150 0.031
ensheathment of neurons GO:0007272 76 0.030
response to oxidative stress GO:0006979 123 0.030
organophosphate biosynthetic process GO:0090407 122 0.030
inorganic ion transmembrane transport GO:0098660 234 0.030
inorganic cation transmembrane transport GO:0098662 207 0.030
response to growth factor GO:0070848 198 0.030
bronchiole morphogenesis GO:0060436 1 0.030
carbohydrate homeostasis GO:0033500 128 0.030
neuron projection guidance GO:0097485 141 0.030
t cell mediated immunity GO:0002456 50 0.030
positive regulation of protein kinase activity GO:0045860 144 0.030
positive regulation of nucleotide metabolic process GO:0045981 114 0.030
multi multicellular organism process GO:0044706 109 0.030
neurotransmitter catabolic process GO:0042135 3 0.029
negative regulation of phospholipase activity GO:0010519 4 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.029
myeloid cell differentiation GO:0030099 233 0.029
regulation of b cell activation GO:0050864 81 0.029
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.029
compound eye development GO:0048749 1 0.029
organic anion transport GO:0015711 137 0.029
negative regulation of blood vessel morphogenesis GO:2000181 25 0.029
nucleoside phosphate metabolic process GO:0006753 338 0.029
negative regulation of nervous system development GO:0051961 156 0.029
cartilage development GO:0051216 140 0.029
urogenital system development GO:0001655 261 0.028
positive regulation of lymphocyte activation GO:0051251 140 0.028
cytokine secretion GO:0050663 72 0.028
response to light stimulus GO:0009416 135 0.028
fatty acid metabolic process GO:0006631 121 0.028
multicellular organism growth GO:0035264 161 0.028
locomotory behavior GO:0007626 195 0.028
Zebrafish Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.028
endomembrane system organization GO:0010256 147 0.027
membrane depolarization GO:0051899 64 0.027
Mouse
positive regulation of kinase activity GO:0033674 155 0.027
glycosyl compound catabolic process GO:1901658 206 0.027
neuron apoptotic process GO:0051402 142 0.027
Mouse
carbohydrate metabolic process GO:0005975 230 0.027
cardiac muscle cell development GO:0055013 39 0.027
membrane organization GO:0061024 245 0.027
positive regulation of angiogenesis GO:0045766 46 0.027
regulation of protein serine threonine kinase activity GO:0071900 157 0.027
cytokine production involved in immune response GO:0002367 34 0.027
cellular response to acid chemical GO:0071229 68 0.027
negative regulation of apoptotic signaling pathway GO:2001234 104 0.027
lipid storage GO:0019915 36 0.027
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.027
regulation of cell size GO:0008361 72 0.027
epithelial cell proliferation GO:0050673 174 0.027
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.026
lung alveolus development GO:0048286 45 0.026
mucopolysaccharide metabolic process GO:1903510 25 0.026
positive regulation of ion transport GO:0043270 65 0.026
trunk segmentation GO:0035290 4 0.026
organelle assembly GO:0070925 177 0.026
establishment of neuroblast polarity GO:0045200 1 0.026
ovulation cycle GO:0042698 59 0.026
submandibular salivary gland formation GO:0060661 1 0.026
homeostasis of number of cells GO:0048872 210 0.026
neurotransmitter transport GO:0006836 76 0.026
multicellular organismal signaling GO:0035637 91 0.026
Zebrafish Mouse
protein ubiquitination GO:0016567 171 0.026
embryonic organ morphogenesis GO:0048562 276 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
positive regulation of growth GO:0045927 104 0.025
nitrogen compound transport GO:0071705 271 0.025
macrophage migration inhibitory factor signaling pathway GO:0035691 2 0.025
reactive oxygen species metabolic process GO:0072593 84 0.025
positive regulation of camp mediated signaling GO:0043950 3 0.025
relaxation of smooth muscle GO:0044557 8 0.025
blastocyst development GO:0001824 80 0.025
regulation of neuron projection development GO:0010975 169 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
cardiac muscle cell differentiation GO:0055007 69 0.025
positive regulation of protein kinase b signaling GO:0051897 32 0.025
transmission of nerve impulse GO:0019226 76 0.025
Zebrafish Mouse
immune response regulating signaling pathway GO:0002764 125 0.024
protein homooligomerization GO:0051260 43 0.024
tube closure GO:0060606 91 0.024
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.024
heparin biosynthetic process GO:0030210 2 0.024
aromatic compound catabolic process GO:0019439 286 0.024
regulation of cell cycle GO:0051726 281 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
regulation of macrophage migration inhibitory factor signaling pathway GO:2000446 1 0.024
cerebral cortex development GO:0021987 86 0.024
heart morphogenesis GO:0003007 178 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.024
spermatid differentiation GO:0048515 115 0.024
regulation of cell substrate adhesion GO:0010810 73 0.024
forebrain development GO:0030900 302 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
extracellular structure organization GO:0043062 148 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.023
telencephalon development GO:0021537 186 0.023
negative regulation of muscle contraction GO:0045932 12 0.023
regulation of cardiac muscle hypertrophy GO:0010611 13 0.023
positive regulation of cell activation GO:0050867 158 0.023
bone development GO:0060348 120 0.023
positive regulation of neuron differentiation GO:0045666 141 0.023
male gamete generation GO:0048232 285 0.023
notch signaling pathway GO:0007219 71 0.023
leukocyte mediated immunity GO:0002443 174 0.023
cellular protein complex assembly GO:0043623 116 0.023
directional locomotion GO:0033058 3 0.023
nuclear import GO:0051170 95 0.023
t helper cell differentiation GO:0042093 28 0.023
regulation of reproductive process GO:2000241 66 0.023
sequestering of metal ion GO:0051238 19 0.023
extrinsic apoptotic signaling pathway GO:0097191 126 0.023
mesenchyme development GO:0060485 152 0.023
lymphocyte homeostasis GO:0002260 64 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
cell fate commitment GO:0045165 210 0.022
lymphocyte activation involved in immune response GO:0002285 93 0.022
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.022
regulation of osteoblast differentiation GO:0045667 67 0.022
myeloid cell homeostasis GO:0002262 114 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
sensory perception of light stimulus GO:0050953 54 0.022
nuclear transport GO:0051169 139 0.022
sequestering of calcium ion GO:0051208 18 0.022
glycosyl compound metabolic process GO:1901657 246 0.022
heart trabecula morphogenesis GO:0061384 26 0.022
sensory organ morphogenesis GO:0090596 242 0.022
b cell activation GO:0042113 161 0.022
smooth muscle cell chemotaxis GO:0071670 2 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
b cell proliferation GO:0042100 53 0.022
positive regulation of cytokine production GO:0001819 174 0.022
regulation of ion homeostasis GO:2000021 64 0.021
Mouse
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.021
nucleocytoplasmic transport GO:0006913 139 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.021
cardiac muscle cell contraction GO:0086003 7 0.021
Mouse
regulation of cellular component size GO:0032535 121 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
tube formation GO:0035148 140 0.021
regulation of multi organism process GO:0043900 111 0.021
regulation of cell migration GO:0030334 219 0.021
peptide metabolic process GO:0006518 46 0.021
cranial nerve development GO:0021545 41 0.021
mesoderm development GO:0007498 100 0.021
nucleoside metabolic process GO:0009116 246 0.021
response to decreased oxygen levels GO:0036293 59 0.021
response to inorganic substance GO:0010035 96 0.021
female sex differentiation GO:0046660 84 0.021
regulation of ossification GO:0030278 112 0.021
nucleotide metabolic process GO:0009117 332 0.021
muscle cell fate specification GO:0042694 1 0.020
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.020
Mouse
protein modification by small protein conjugation GO:0032446 187 0.020
regulation of calcium ion transport GO:0051924 69 0.020
regulation of organ morphogenesis GO:2000027 144 0.020
retina development in camera type eye GO:0060041 119 0.020
regulation of renal sodium excretion GO:0035813 3 0.020
developmental cell growth GO:0048588 84 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
regulation of muscle hypertrophy GO:0014743 13 0.020
positive regulation of defense response GO:0031349 124 0.020
negative regulation of protein modification process GO:0031400 163 0.020
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.020
female genitalia morphogenesis GO:0048807 3 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.020
cardiac chamber development GO:0003205 108 0.020
Mouse
regulation of fibroblast proliferation GO:0048145 34 0.019
neuron death GO:0070997 154 0.019
Mouse
regulation of erk1 and erk2 cascade GO:0070372 71 0.019
positive regulation of vasoconstriction GO:0045907 4 0.019
cell recognition GO:0008037 83 0.019
embryonic placenta development GO:0001892 98 0.019
regulation of white fat cell proliferation GO:0070350 2 0.019
protein processing GO:0016485 163 0.019
organ growth GO:0035265 117 0.019
striated muscle hypertrophy GO:0014897 24 0.019
hormone secretion GO:0046879 128 0.019
regulation of cytoskeleton organization GO:0051493 122 0.019
connective tissue development GO:0061448 179 0.019
calcium ion transmembrane transport GO:0070588 85 0.019
regulation of aldosterone metabolic process GO:0032344 1 0.019
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.019
development of primary female sexual characteristics GO:0046545 73 0.019
alcohol metabolic process GO:0006066 116 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
anion transport GO:0006820 177 0.019
regulation of morphogenesis of a branching structure GO:0060688 53 0.019
epidermis development GO:0008544 187 0.019
glial cell differentiation GO:0010001 131 0.019
regulation of cytokine production GO:0001817 266 0.019
purine nucleotide biosynthetic process GO:0006164 65 0.019
protein maturation GO:0051604 176 0.019
positive regulation of cell development GO:0010720 237 0.018
negative regulation of organelle organization GO:0010639 90 0.018
regulation of protein targeting GO:1903533 61 0.018
regulation of muscle adaptation GO:0043502 31 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
cardiac muscle fiber development GO:0048739 4 0.018
cellular calcium ion homeostasis GO:0006874 119 0.018
myelination GO:0042552 74 0.018
interleukin 6 production GO:0032635 58 0.018
purine containing compound metabolic process GO:0072521 311 0.018
response to symbiont GO:0009608 2 0.018
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.018
negative regulation of defense response GO:0031348 77 0.018
learning GO:0007612 98 0.018
stem cell proliferation GO:0072089 117 0.018
negative regulation of response to wounding GO:1903035 77 0.018
regulation of high voltage gated calcium channel activity GO:1901841 2 0.018
single organism nuclear import GO:1902593 95 0.018
positive regulation of endocytosis GO:0045807 42 0.018
organelle localization GO:0051640 179 0.018
placenta development GO:0001890 140 0.018
stem cell maintenance GO:0019827 130 0.018
positive regulation of high voltage gated calcium channel activity GO:1901843 1 0.018
regulation of muscle contraction GO:0006937 49 0.018
Mouse
fibroblast proliferation GO:0048144 35 0.018
plasma membrane organization GO:0007009 90 0.018
metencephalon development GO:0022037 89 0.018
leukocyte mediated cytotoxicity GO:0001909 62 0.018
harderian gland development GO:0070384 2 0.018
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.018

Scn7a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 0 0.109
disease of anatomical entity DOID:7 0 0.109
muscle tissue disease DOID:66 0 0.053
cardiomyopathy DOID:0050700 0 0.053
dilated cardiomyopathy DOID:12930 0 0.053
heart disease DOID:114 0 0.053
muscular disease DOID:0080000 0 0.053
intrinsic cardiomyopathy DOID:0060036 0 0.053
myopathy DOID:423 0 0.053
musculoskeletal system disease DOID:17 0 0.053
nervous system disease DOID:863 0 0.039
sensory system disease DOID:0050155 0 0.020