Mus musculus

27 known processes

Scn8a

sodium channel, voltage-gated, type VIII, alpha

(Aliases: AI853486,C630029C19Rik,mnd2,nur14,Nav1.6,med,mnd-2,nmf2,nmf335,dmu,nmf58,NaCh6,seal)

Scn8a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 329 0.914
inorganic ion transmembrane transport GO:0098660 234 0.763
Zebrafish Mouse Rat
inorganic cation transmembrane transport GO:0098662 207 0.657
Zebrafish Mouse Rat
cation transmembrane transport GO:0098655 266 0.654
Zebrafish Mouse Rat
microtubule based movement GO:0007018 84 0.633
ion transmembrane transport GO:0034220 361 0.609
Zebrafish Mouse Rat
regulation of membrane potential GO:0042391 192 0.570
Mouse Rat
establishment of organelle localization GO:0051656 122 0.549
regulation of neurotransmitter levels GO:0001505 87 0.473
establishment of vesicle localization GO:0051650 81 0.463
neurotransmitter secretion GO:0007269 62 0.455
transmembrane transport GO:0055085 412 0.450
Zebrafish Mouse Rat
vesicle localization GO:0051648 86 0.445
action potential GO:0001508 78 0.426
Mouse Rat
synaptic vesicle localization GO:0097479 59 0.410
synaptic vesicle transport GO:0048489 57 0.403
establishment of synaptic vesicle localization GO:0097480 57 0.394
neurotransmitter transport GO:0006836 76 0.389
locomotory behavior GO:0007626 195 0.370
cation transport GO:0006812 399 0.347
Zebrafish Mouse Rat
regulation of ion transport GO:0043269 215 0.344
Zebrafish Mouse Rat
sensory perception of sound GO:0007605 97 0.331
exocytosis GO:0006887 121 0.326
regulation of neuron projection development GO:0010975 169 0.310
membrane depolarization GO:0051899 64 0.294
Mouse
sensory perception GO:0007600 245 0.242
calcium ion transmembrane transport GO:0070588 85 0.239
calcium ion dependent exocytosis GO:0017156 35 0.234
regulation of neurotransmitter secretion GO:0046928 29 0.231
potassium ion transmembrane transport GO:0071805 43 0.226
adult behavior GO:0030534 135 0.203
divalent inorganic cation transport GO:0072511 178 0.203
cytoskeleton dependent intracellular transport GO:0030705 50 0.202
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.201
regulation of neuron differentiation GO:0045664 281 0.193
regulation of secretion GO:0051046 274 0.188
calcium ion dependent exocytosis of neurotransmitter GO:0048791 7 0.185
cellular potassium ion transport GO:0071804 43 0.179
cell adhesion GO:0007155 329 0.177
synapse organization GO:0050808 125 0.176
regulation of synaptic plasticity GO:0048167 87 0.166
dendrite development GO:0016358 115 0.152
neuron projection guidance GO:0097485 141 0.141
Zebrafish
calcium ion transport GO:0006816 159 0.141
neuron neuron synaptic transmission GO:0007270 69 0.139
microtubule based transport GO:0010970 50 0.139
regulation of metal ion transport GO:0010959 106 0.137
learning GO:0007612 98 0.135
nitrogen compound transport GO:0071705 271 0.135
establishment of mitochondrion localization GO:0051654 4 0.133
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.133
divalent metal ion transport GO:0070838 172 0.129
detection of stimulus GO:0051606 84 0.128
sa node cell action potential GO:0086015 4 0.123
Mouse
developmental maturation GO:0021700 193 0.120
positive regulation of cell development GO:0010720 237 0.119
transmission of nerve impulse GO:0019226 76 0.115
Mouse Rat
adult walking behavior GO:0007628 41 0.113
intracellular protein transport GO:0006886 204 0.112
organelle localization GO:0051640 179 0.111
cellular amino acid metabolic process GO:0006520 103 0.110
acetylcholine transport GO:0015870 2 0.109
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.109
regulation of cellular component biogenesis GO:0044087 181 0.108
hindbrain maturation GO:0021578 6 0.107
synaptic vesicle priming GO:0016082 8 0.104
central nervous system maturation GO:0021626 6 0.104
potassium ion transport GO:0006813 52 0.104
learning or memory GO:0007611 148 0.103
sensory organ morphogenesis GO:0090596 242 0.103
microtubule based process GO:0007017 236 0.101
fast calcium ion dependent exocytosis of neurotransmitter GO:0098746 1 0.100
amine metabolic process GO:0009308 45 0.098
membrane organization GO:0061024 245 0.098
microtubule cytoskeleton organization GO:0000226 157 0.093
multicellular organismal signaling GO:0035637 91 0.091
Mouse Rat
chemotaxis GO:0006935 247 0.089
Zebrafish
regulation of feeding behavior GO:0060259 3 0.089
sensory perception of light stimulus GO:0050953 54 0.086
neuronal action potential GO:0019228 54 0.084
Mouse Rat
macromolecule catabolic process GO:0009057 281 0.084
ensheathment of neurons GO:0007272 76 0.083
Rat
regulation of nucleoside metabolic process GO:0009118 130 0.081
synaptic vesicle recycling GO:0036465 19 0.081
mitochondrion transport along microtubule GO:0047497 3 0.080
photoreceptor cell maintenance GO:0045494 19 0.080
multicellular organism growth GO:0035264 161 0.080
developmental cell growth GO:0048588 84 0.079
acetylcholine secretion neurotransmission GO:0014055 2 0.079
cognition GO:0050890 149 0.079
regulation of cell projection organization GO:0031344 206 0.079
peptide transport GO:0015833 133 0.076
calcium ion homeostasis GO:0055074 127 0.075
defecation GO:0030421 1 0.075
engulfment of apoptotic cell GO:0043652 3 0.073
regulation of secretion by cell GO:1903530 249 0.073
single organism cell adhesion GO:0098602 156 0.073
sodium ion transmembrane transport GO:0035725 49 0.072
Zebrafish Mouse Rat
adult locomotory behavior GO:0008344 91 0.072
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.071
nucleoside phosphate catabolic process GO:1901292 222 0.071
gliogenesis GO:0042063 141 0.071
response to radiation GO:0009314 165 0.070
regulation of cellular amino acid metabolic process GO:0006521 5 0.070
regulation of neurotransmitter transport GO:0051588 35 0.070
positive regulation of neuron projection development GO:0010976 79 0.069
vesicle organization GO:0016050 60 0.068
nucleoside triphosphate metabolic process GO:0009141 230 0.067
regulation of vesicle mediated transport GO:0060627 139 0.067
regulation of transmembrane transport GO:0034762 128 0.066
Zebrafish Mouse Rat
ear development GO:0043583 200 0.066
muscle fiber development GO:0048747 76 0.065
visual perception GO:0007601 52 0.065
regulation of anatomical structure size GO:0090066 178 0.065
regulation of t cell activation GO:0050863 170 0.065
anatomical structure homeostasis GO:0060249 145 0.064
glial cell development GO:0021782 54 0.061
ribose phosphate metabolic process GO:0019693 291 0.061
insulin secretion GO:0030073 89 0.061
fertilization GO:0009566 127 0.061
regulation of ion transmembrane transporter activity GO:0032412 54 0.061
cation homeostasis GO:0055080 212 0.061
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.061
skeletal system development GO:0001501 356 0.059
retina homeostasis GO:0001895 23 0.059
divalent inorganic cation homeostasis GO:0072507 138 0.059
cellular chemical homeostasis GO:0055082 215 0.058
regulation of axon extension GO:0030516 43 0.058
single organismal cell cell adhesion GO:0016337 131 0.058
apoptotic signaling pathway GO:0097190 306 0.058
Mouse
regulation of intracellular transport GO:0032386 159 0.058
maintenance of presynaptic active zone structure GO:0048790 1 0.057
nucleoside catabolic process GO:0009164 206 0.057
regulation of cellular catabolic process GO:0031329 242 0.057
associative learning GO:0008306 61 0.057
regulation of neuronal synaptic plasticity GO:0048168 30 0.056
synaptic vesicle exocytosis GO:0016079 26 0.056
response to light stimulus GO:0009416 135 0.056
positive regulation of necrotic cell death GO:0010940 1 0.056
membrane fusion GO:0061025 38 0.055
synaptic transmission glutamatergic GO:0035249 36 0.055
regulation of ion transmembrane transport GO:0034765 119 0.055
Zebrafish Mouse Rat
cerebellum development GO:0021549 77 0.054
regulation of exocytosis GO:0017157 61 0.054
neuromuscular synaptic transmission GO:0007274 16 0.054
cellular component assembly involved in morphogenesis GO:0010927 139 0.054
synaptic transmission cholinergic GO:0007271 7 0.053
regulation of cytoskeleton organization GO:0051493 122 0.053
multicellular organismal homeostasis GO:0048871 164 0.053
potassium ion homeostasis GO:0055075 4 0.053
single fertilization GO:0007338 82 0.053
purine nucleoside triphosphate metabolic process GO:0009144 226 0.052
myelination GO:0042552 74 0.052
Rat
protein catabolic process GO:0030163 221 0.052
leukocyte differentiation GO:0002521 342 0.052
eye photoreceptor cell differentiation GO:0001754 41 0.051
regulation of cellular ketone metabolic process GO:0010565 66 0.051
glycosyl compound catabolic process GO:1901658 206 0.051
cellular homeostasis GO:0019725 240 0.051
positive regulation of nervous system development GO:0051962 221 0.050
regulation of systemic arterial blood pressure GO:0003073 61 0.049
carbohydrate derivative catabolic process GO:1901136 231 0.049
regulation of protein localization GO:0032880 231 0.049
cell growth GO:0016049 130 0.049
extracellular matrix organization GO:0030198 147 0.049
anion transport GO:0006820 177 0.049
regulation of cellular component size GO:0032535 121 0.048
ribonucleoside triphosphate catabolic process GO:0009203 199 0.048
nucleotide catabolic process GO:0009166 217 0.048
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.048
clathrin coat assembly GO:0048268 2 0.048
synapse assembly GO:0007416 56 0.048
regulation of organelle organization GO:0033043 289 0.048
pole plasm assembly GO:0007315 2 0.047
detection of light stimulus GO:0009583 25 0.047
glial cell differentiation GO:0010001 131 0.047
inorganic anion transport GO:0015698 43 0.046
excretion GO:0007588 22 0.045
cell recognition GO:0008037 83 0.045
peptide secretion GO:0002790 114 0.045
positive regulation of vesicle fusion GO:0031340 2 0.045
positive regulation of growth GO:0045927 104 0.045
regulation of g protein activated inward rectifier potassium channel activity GO:1900128 1 0.045
response to organonitrogen compound GO:0010243 246 0.044
heart process GO:0003015 94 0.044
Mouse
neuron projection extension GO:1990138 64 0.044
regulation of hormone levels GO:0010817 211 0.044
amide transport GO:0042886 138 0.043
establishment of glial blood brain barrier GO:0060857 2 0.043
regulation of protein kinase activity GO:0045859 232 0.042
cellular protein complex assembly GO:0043623 116 0.042
regulation of hormone secretion GO:0046883 88 0.042
organonitrogen compound biosynthetic process GO:1901566 192 0.042
memory GO:0007613 58 0.042
purine nucleoside triphosphate catabolic process GO:0009146 203 0.041
ribonucleotide metabolic process GO:0009259 291 0.041
cellular lipid metabolic process GO:0044255 323 0.040
regulation of cell adhesion GO:0030155 154 0.039
membrane depolarization during sa node cell action potential GO:0086046 2 0.039
Mouse
cell maturation GO:0048469 127 0.039
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
gamma aminobutyric acid transport GO:0015812 7 0.039
axonogenesis GO:0007409 274 0.039
Zebrafish
metal ion homeostasis GO:0055065 189 0.039
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.038
regulation of postsynaptic membrane potential GO:0060078 48 0.038
axon cargo transport GO:0008088 33 0.038
actin filament organization GO:0007015 113 0.038
chloride transport GO:0006821 32 0.038
cellular response to carbohydrate stimulus GO:0071322 50 0.038
actin cytoskeleton organization GO:0030036 220 0.038
positive regulation of secretion by cell GO:1903532 114 0.038
g protein coupled receptor signaling pathway GO:0007186 243 0.038
regulation of body fluid levels GO:0050878 162 0.038
negative regulation of mapk cascade GO:0043409 65 0.037
plus end directed organelle transport along microtubule GO:0072386 2 0.037
positive regulation of nucleoside metabolic process GO:0045979 91 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.037
negative regulation of phosphorylation GO:0042326 166 0.036
regulation of purine nucleotide catabolic process GO:0033121 122 0.036
response to temperature stimulus GO:0009266 55 0.036
olfactory learning GO:0008355 2 0.036
fear response GO:0042596 33 0.036
negative regulation of hormone metabolic process GO:0032351 4 0.035
maternal determination of anterior posterior axis embryo GO:0008358 2 0.035
ossification GO:0001503 216 0.035
positive regulation of protein modification process GO:0031401 299 0.034
mating GO:0007618 27 0.034
immune effector process GO:0002252 321 0.034
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.034
cellular metal ion homeostasis GO:0006875 151 0.034
protein localization to juxtaparanode region of axon GO:0071205 4 0.033
purine containing compound metabolic process GO:0072521 311 0.033
cytoplasmic transport GO:0016482 234 0.033
protein localization to membrane GO:0072657 108 0.033
cellular response to monosaccharide stimulus GO:0071326 47 0.033
hormone secretion GO:0046879 128 0.033
regulation of cell motility GO:2000145 236 0.033
endocytosis GO:0006897 168 0.032
regulation of lipid metabolic process GO:0019216 118 0.032
purine containing compound catabolic process GO:0072523 213 0.032
central nervous system projection neuron axonogenesis GO:0021952 21 0.032
ras protein signal transduction GO:0007265 77 0.032
regulation of multi organism process GO:0043900 111 0.032
dephosphorylation GO:0016311 129 0.031
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.031
Mouse
cellular ketone metabolic process GO:0042180 84 0.031
negative regulation of phosphorus metabolic process GO:0010563 184 0.031
positive regulation of protein kinase activity GO:0045860 144 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.031
canonical wnt signaling pathway GO:0060070 130 0.031
acrosome reaction GO:0007340 19 0.031
neuron death GO:0070997 154 0.031
Mouse
medulla oblongata development GO:0021550 3 0.031
regulation of hydrolase activity GO:0051336 246 0.030
reflex GO:0060004 22 0.030
detection of abiotic stimulus GO:0009582 60 0.030
ribonucleotide catabolic process GO:0009261 208 0.030
regulation of calcium ion transport GO:0051924 69 0.030
regulation of mapk cascade GO:0043408 248 0.029
male courtship behavior GO:0008049 2 0.029
cellular calcium ion homeostasis GO:0006874 119 0.029
axon ensheathment GO:0008366 76 0.029
Rat
regulation of nucleotide metabolic process GO:0006140 169 0.029
circulatory system process GO:0003013 197 0.029
Mouse
lipid biosynthetic process GO:0008610 179 0.028
regulation of homeostatic process GO:0032844 182 0.028
Mouse
t cell activation GO:0042110 289 0.028
axonal fasciculation GO:0007413 15 0.028
cell junction organization GO:0034330 77 0.028
determination of left right asymmetry in nervous system GO:0035545 1 0.028
organ growth GO:0035265 117 0.028
protein autophosphorylation GO:0046777 61 0.028
long term synaptic potentiation GO:0060291 25 0.028
sperm motility GO:0030317 47 0.028
oocyte axis specification GO:0007309 2 0.028
cell junction assembly GO:0034329 52 0.027
central nervous system neuron differentiation GO:0021953 162 0.027
regulation of endocytosis GO:0030100 69 0.027
small gtpase mediated signal transduction GO:0007264 97 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.027
peptidyl serine phosphorylation GO:0018105 74 0.027
hindbrain development GO:0030902 128 0.027
establishment of blood brain barrier GO:0060856 8 0.027
regulation of defense response GO:0031347 233 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.027
regulation of cellular response to growth factor stimulus GO:0090287 82 0.027
regulation of gtp catabolic process GO:0033124 113 0.027
nucleoside triphosphate catabolic process GO:0009143 205 0.027
response to transforming growth factor beta GO:0071559 88 0.026
peptide hormone secretion GO:0030072 109 0.026
regulation of calcium ion dependent exocytosis GO:0017158 16 0.026
gland development GO:0048732 330 0.026
organophosphate catabolic process GO:0046434 232 0.026
positive regulation of excitatory postsynaptic membrane potential GO:2000463 14 0.026
regulation of neuron death GO:1901214 134 0.026
negative regulation of neuron death GO:1901215 98 0.026
response to endoplasmic reticulum stress GO:0034976 53 0.026
gamma aminobutyric acid secretion GO:0014051 6 0.026
regulation of potassium ion transmembrane transporter activity GO:1901016 7 0.026
positive regulation of map kinase activity GO:0043406 84 0.026
sodium ion transport GO:0006814 73 0.026
Zebrafish Mouse Rat
protein localization to organelle GO:0033365 185 0.026
membrane hyperpolarization GO:0060081 21 0.026
regulation of voltage gated calcium channel activity GO:1901385 4 0.026
organelle fusion GO:0048284 28 0.025
endoplasmic reticulum organization GO:0007029 10 0.025
positive regulation of cellular catabolic process GO:0031331 148 0.025
mapk cascade GO:0000165 281 0.025
axon guidance GO:0007411 141 0.025
Zebrafish
protein polymerization GO:0051258 57 0.025
positive regulation of transferase activity GO:0051347 167 0.025
regulation of cell cycle GO:0051726 281 0.025
renal system development GO:0072001 225 0.025
multi organism reproductive behavior GO:0044705 29 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
blood circulation GO:0008015 195 0.024
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.024
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.024
negative regulation of multi organism process GO:0043901 68 0.024
acetate ester transport GO:1901374 2 0.024
carbohydrate homeostasis GO:0033500 128 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
muscle cell differentiation GO:0042692 261 0.024
heterocycle catabolic process GO:0046700 280 0.024
oocyte anterior posterior axis specification GO:0007314 2 0.024
regulation of purine nucleotide metabolic process GO:1900542 169 0.024
regulation of synaptic vesicle transport GO:1902803 13 0.024
respiratory tube development GO:0030323 167 0.024
photoreceptor cell differentiation GO:0046530 52 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
plasma membrane organization GO:0007009 90 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
central nervous system neuron development GO:0021954 67 0.024
negative regulation of neuron differentiation GO:0045665 101 0.024
phagocytosis GO:0006909 66 0.024
regulation of organ growth GO:0046620 61 0.024
maintenance of location GO:0051235 89 0.024
inorganic anion transmembrane transport GO:0098661 29 0.024
regulation of glial cell differentiation GO:0045685 41 0.023
cerebellum morphogenesis GO:0021587 42 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
vestibular nucleus development GO:0021750 2 0.023
phospholipid metabolic process GO:0006644 87 0.023
smooth muscle contraction involved in micturition GO:0060083 3 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
establishment of protein localization to organelle GO:0072594 118 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
neuromuscular process controlling balance GO:0050885 59 0.022
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
negative regulation of phosphate metabolic process GO:0045936 184 0.022
response to growth factor GO:0070848 198 0.022
regulation of proteolysis GO:0030162 164 0.022
cerebellar purkinje cell layer development GO:0021680 26 0.022
amino acid transport GO:0006865 61 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
peptidyl amino acid modification GO:0018193 336 0.022
regulation of protein maturation GO:1903317 96 0.022
regulation of nucleotide catabolic process GO:0030811 122 0.022
protein import into nucleus GO:0006606 95 0.022
protein autoprocessing GO:0016540 2 0.021
response to monosaccharide GO:0034284 67 0.021
mating behavior sex discrimination GO:0048047 1 0.021
regulation of cell growth GO:0001558 91 0.021
multi organism behavior GO:0051705 62 0.021
cellular response to hexose stimulus GO:0071331 47 0.021
phototransduction GO:0007602 17 0.021
regulation of astrocyte differentiation GO:0048710 20 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
oocyte construction GO:0007308 2 0.021
sulfur compound metabolic process GO:0006790 100 0.021
oligodendrocyte development GO:0014003 20 0.021
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.020
regulation of cell size GO:0008361 72 0.020
regulation of cell migration GO:0030334 219 0.020
calcium mediated signaling using intracellular calcium source GO:0035584 3 0.020
sensory perception of mechanical stimulus GO:0050954 107 0.020
synaptic vesicle fusion to presynaptic membrane GO:0031629 3 0.020
germ cell development GO:0007281 185 0.020
regulation of protein catabolic process GO:0042176 108 0.020
sensory system development GO:0048880 3 0.020
muscle cell development GO:0055001 133 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
regulation of system process GO:0044057 200 0.020
Mouse
regulation of synaptic vesicle priming GO:0010807 4 0.019
male gamete generation GO:0048232 285 0.019
establishment of blood nerve barrier GO:0008065 3 0.019
metencephalon development GO:0022037 89 0.019
skin development GO:0043588 220 0.019
hormone metabolic process GO:0042445 86 0.019
positive regulation of nucleotide metabolic process GO:0045981 114 0.019
cell division GO:0051301 120 0.019
regulation of cellular amine metabolic process GO:0033238 20 0.019
detection of stimulus involved in sensory perception GO:0050906 44 0.019
tissue homeostasis GO:0001894 115 0.019
positive regulation of membrane potential GO:0045838 15 0.019
mitotic cytokinesis GO:0000281 4 0.019
negative regulation of cell development GO:0010721 169 0.019
erk1 and erk2 cascade GO:0070371 77 0.019
regulation of synaptic transmission glutamatergic GO:0051966 19 0.019
positive regulation of nucleotide catabolic process GO:0030813 88 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
response to organic cyclic compound GO:0014070 198 0.019
Mouse
cell cell junction organization GO:0045216 72 0.019
ephrin receptor signaling pathway GO:0048013 20 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
positive regulation of secretion GO:0051047 130 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
regulation of synapse assembly GO:0051963 29 0.018
multi multicellular organism process GO:0044706 109 0.018
cytosolic calcium ion homeostasis GO:0051480 70 0.018
endomembrane system organization GO:0010256 147 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.018
cellular amine metabolic process GO:0044106 44 0.018
cardiac muscle cell action potential GO:0086001 11 0.018
Mouse
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.018
regulation of blood circulation GO:1903522 93 0.018
Mouse
negative regulation of cellular component organization GO:0051129 194 0.018
female gamete generation GO:0007292 74 0.018
positive regulation of neuron differentiation GO:0045666 141 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
optic nerve structural organization GO:0021633 2 0.018
nucleotide metabolic process GO:0009117 332 0.018
negative regulation of neuron apoptotic process GO:0043524 92 0.018
somatostatin receptor signaling pathway GO:0038169 2 0.018
regulation of peptide transport GO:0090087 91 0.018
regulation of cellular response to stress GO:0080135 159 0.018
reproductive behavior GO:0019098 32 0.018
positive regulation of cell adhesion GO:0045785 80 0.017
negative regulation of neuron projection development GO:0010977 50 0.017
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
acid secretion GO:0046717 33 0.017
regulation of potassium ion transmembrane transport GO:1901379 11 0.017
establishment or maintenance of cell polarity GO:0007163 86 0.017
terminal button organization GO:0072553 3 0.017
peptide metabolic process GO:0006518 46 0.017
regulation of clathrin mediated endocytosis GO:2000369 4 0.017
neural nucleus development GO:0048857 22 0.017
sensory perception of pain GO:0019233 47 0.017
Mouse
regulation of transferase activity GO:0051338 263 0.017
vesicle fusion GO:0006906 16 0.017
compound eye development GO:0048749 1 0.017
synaptic vesicle endocytosis GO:0048488 19 0.017
female gonad development GO:0008585 71 0.017
positive regulation of apoptotic signaling pathway GO:2001235 95 0.017
regulation of neuron apoptotic process GO:0043523 122 0.017
striated muscle contraction GO:0006941 45 0.017
Mouse
purine nucleotide catabolic process GO:0006195 211 0.017
mesenchyme development GO:0060485 152 0.017
pons development GO:0021548 13 0.017
protein processing GO:0016485 163 0.017
gtp metabolic process GO:0046039 144 0.016
detection of external stimulus GO:0009581 61 0.016
protein maturation GO:0051604 176 0.016
negative regulation of cell projection organization GO:0031345 56 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
regulation of extent of cell growth GO:0061387 52 0.016
cellular response to organic cyclic compound GO:0071407 87 0.016
organelle transport along microtubule GO:0072384 14 0.016
response to histamine GO:0034776 1 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
regulation of ras gtpase activity GO:0032318 88 0.016
membrane tubulation GO:0097320 4 0.016
regulation of kinase activity GO:0043549 249 0.016
amino acid import into cell GO:1902837 4 0.016
striated muscle cell development GO:0055002 125 0.016
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.016
cellular monovalent inorganic anion homeostasis GO:0030320 4 0.016
regulation of reproductive process GO:2000241 66 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.016
regulation of phagocytosis GO:0050764 33 0.016
neuron migration GO:0001764 122 0.015
response to osmotic stress GO:0006970 21 0.015
Mouse
regulation of map kinase activity GO:0043405 120 0.015
protein targeting GO:0006605 143 0.015
regulation of peptide hormone secretion GO:0090276 75 0.015
cerebellar purkinje cell differentiation GO:0021702 13 0.015
regulation of engulfment of apoptotic cell GO:1901074 2 0.015
stress activated protein kinase signaling cascade GO:0031098 81 0.015
cell substrate adhesion GO:0031589 130 0.015
intracellular mrna localization GO:0008298 4 0.015
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.015
golgi to endosome transport GO:0006895 3 0.015
negative regulation of immune system process GO:0002683 209 0.015
regulation of axon diameter GO:0031133 6 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
retina development in camera type eye GO:0060041 119 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015

Scn8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.045
central nervous system disease DOID:331 0 0.023