Mus musculus

0 known processes

Sdha

succinate dehydrogenase complex, subunit A, flavoprotein (Fp)

(Aliases: FP,1500032O14Rik,SDH2,2310034D06Rik,4921513A11,C81073,SDHF)

Sdha biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.943
Yeast
energy derivation by oxidation of organic compounds GO:0015980 77 0.783
Yeast
generation of precursor metabolites and energy GO:0006091 103 0.701
Yeast
coenzyme metabolic process GO:0006732 52 0.627
fatty acid oxidation GO:0019395 28 0.355
small molecule catabolic process GO:0044282 71 0.320
cellular respiration GO:0045333 38 0.235
Yeast
mitochondrion organization GO:0007005 134 0.195
nadh metabolic process GO:0006734 1 0.195
monocarboxylic acid metabolic process GO:0032787 191 0.191
lipid oxidation GO:0034440 29 0.183
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.182
coenzyme biosynthetic process GO:0009108 23 0.170
thioester metabolic process GO:0035383 19 0.167
transmembrane transport GO:0055085 412 0.164
cellular amino acid metabolic process GO:0006520 103 0.151
acetyl coa biosynthetic process GO:0006085 5 0.125
mitochondrial translation GO:0032543 4 0.124
cellular ketone metabolic process GO:0042180 84 0.113
nucleotide metabolic process GO:0009117 332 0.112
Yeast
organic cyclic compound catabolic process GO:1901361 295 0.091
fatty acid catabolic process GO:0009062 25 0.086
carboxylic acid catabolic process GO:0046395 51 0.081
protein targeting GO:0006605 143 0.079
acyl coa metabolic process GO:0006637 19 0.079
organic acid catabolic process GO:0016054 51 0.073
nucleoside phosphate metabolic process GO:0006753 338 0.071
Yeast
cellular nitrogen compound catabolic process GO:0044270 280 0.070
citrate metabolic process GO:0006101 3 0.068
nucleobase containing small molecule metabolic process GO:0055086 352 0.068
Yeast
heterocycle catabolic process GO:0046700 280 0.067
sulfur compound metabolic process GO:0006790 100 0.066
thioester biosynthetic process GO:0035384 7 0.065
regulation of cellular ketone metabolic process GO:0010565 66 0.064
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.064
Yeast
organonitrogen compound catabolic process GO:1901565 264 0.059
lipid catabolic process GO:0016042 69 0.058
glycosyl compound metabolic process GO:1901657 246 0.057
Yeast
cellular lipid metabolic process GO:0044255 323 0.057
tricarboxylic acid metabolic process GO:0072350 5 0.057
organic hydroxy compound metabolic process GO:1901615 203 0.053
ribonucleoside triphosphate metabolic process GO:0009199 220 0.052
Yeast
mitochondrial membrane organization GO:0007006 26 0.051
purine nucleoside triphosphate catabolic process GO:0009146 203 0.051
aromatic compound catabolic process GO:0019439 286 0.050
protein localization to organelle GO:0033365 185 0.049
alpha amino acid metabolic process GO:1901605 59 0.047
cellular macromolecule catabolic process GO:0044265 206 0.046
intracellular protein transport GO:0006886 204 0.044
succinyl coa metabolic process GO:0006104 1 0.043
organophosphate catabolic process GO:0046434 232 0.041
translation GO:0006412 93 0.040
carnitine metabolic process GO:0009437 7 0.040
inorganic ion transmembrane transport GO:0098660 234 0.039
regulation of mitochondrion organization GO:0010821 27 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.039
Yeast
ether metabolic process GO:0018904 2 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
neuron apoptotic process GO:0051402 142 0.038
mitochondrial transport GO:0006839 36 0.038
purine nucleoside metabolic process GO:0042278 241 0.037
Yeast
cell type specific apoptotic process GO:0097285 268 0.037
negative regulation of cell proliferation GO:0008285 296 0.036
regulation of membrane potential GO:0042391 192 0.036
protein oxidation GO:0018158 2 0.035
cellular modified amino acid metabolic process GO:0006575 63 0.035
cellular amino acid catabolic process GO:0009063 25 0.035
negative regulation of phosphorus metabolic process GO:0010563 184 0.034
intrinsic apoptotic signaling pathway GO:0097193 132 0.034
hepaticobiliary system development GO:0061008 67 0.034
neuron death GO:0070997 154 0.034
apoptotic signaling pathway GO:0097190 306 0.034
response to oxidative stress GO:0006979 123 0.033
ribonucleoside catabolic process GO:0042454 206 0.033
purine containing compound catabolic process GO:0072523 213 0.033
endocytosis GO:0006897 168 0.033
cellular lipid catabolic process GO:0044242 52 0.033
sulfur compound biosynthetic process GO:0044272 37 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.032
Yeast
dicarboxylic acid metabolic process GO:0043648 18 0.032
cellular amine metabolic process GO:0044106 44 0.032
purine nucleotide catabolic process GO:0006195 211 0.031
establishment of protein localization to peroxisome GO:0072663 4 0.031
amine metabolic process GO:0009308 45 0.031
nitrogen compound transport GO:0071705 271 0.031
ribonucleotide metabolic process GO:0009259 291 0.030
Yeast
ribose phosphate metabolic process GO:0019693 291 0.030
Yeast
cation transport GO:0006812 399 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.029
Yeast
homeostasis of number of cells GO:0048872 210 0.029
atp metabolic process GO:0046034 75 0.029
Yeast
microtubule based process GO:0007017 236 0.029
establishment of protein localization to organelle GO:0072594 118 0.029
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.028
medium chain fatty acid metabolic process GO:0051791 1 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
Yeast
monocarboxylic acid biosynthetic process GO:0072330 61 0.027
macromolecule catabolic process GO:0009057 281 0.027
fatty acid beta oxidation GO:0006635 16 0.027
lipid localization GO:0010876 126 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
regulation of neuron death GO:1901214 134 0.026
lipid biosynthetic process GO:0008610 179 0.026
microtubule cytoskeleton organization GO:0000226 157 0.026
regulation of mitochondrial fission GO:0090140 3 0.025
fatty acid metabolic process GO:0006631 121 0.025
atp catabolic process GO:0006200 55 0.025
nucleoside metabolic process GO:0009116 246 0.025
Yeast
cation transmembrane transport GO:0098655 266 0.025
carbohydrate derivative catabolic process GO:1901136 231 0.025
negative regulation of phosphorylation GO:0042326 166 0.025
peptidyl amino acid modification GO:0018193 336 0.024
positive regulation of protein modification process GO:0031401 299 0.024
carboxylic acid biosynthetic process GO:0046394 86 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
positive regulation of mapk cascade GO:0043410 170 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
Yeast
regulation of cellular amine metabolic process GO:0033238 20 0.024
ribonucleotide catabolic process GO:0009261 208 0.023
protein import GO:0017038 101 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
regulation of cellular catabolic process GO:0031329 242 0.023
small molecule biosynthetic process GO:0044283 132 0.022
nuclear transport GO:0051169 139 0.022
nicotinamide nucleotide metabolic process GO:0046496 12 0.022
male gamete generation GO:0048232 285 0.022
energy reserve metabolic process GO:0006112 39 0.022
organic acid biosynthetic process GO:0016053 86 0.021
cellular homeostasis GO:0019725 240 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
protein oligomerization GO:0051259 67 0.021
cellular carbohydrate metabolic process GO:0044262 119 0.021
nucleotide catabolic process GO:0009166 217 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
cellular alcohol metabolic process GO:0044107 3 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.020
response to oxygen radical GO:0000305 16 0.020
cytoplasmic transport GO:0016482 234 0.020
response to inorganic substance GO:0010035 96 0.020
alpha amino acid catabolic process GO:1901606 18 0.020
epithelial cell proliferation GO:0050673 174 0.020
purine nucleoside monophosphate catabolic process GO:0009128 58 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
gland development GO:0048732 330 0.019
glycerol ether metabolic process GO:0006662 2 0.019
establishment of protein localization to membrane GO:0090150 54 0.019
regulation of transferase activity GO:0051338 263 0.019
myeloid cell differentiation GO:0030099 233 0.019
action potential GO:0001508 78 0.019
regulation of organelle organization GO:0033043 289 0.019
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
regulation of cellular response to stress GO:0080135 159 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
response to molecule of bacterial origin GO:0002237 143 0.018
fatty acid alpha oxidation GO:0001561 2 0.018
glycogen biosynthetic process GO:0005978 14 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
aldehyde catabolic process GO:0046185 4 0.018
mitochondrion degradation GO:0000422 3 0.018
glycogen metabolic process GO:0005977 32 0.018
response to organonitrogen compound GO:0010243 246 0.018
regulation of peptide transport GO:0090087 91 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
protein localization to membrane GO:0072657 108 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.017
regulation of kinase activity GO:0043549 249 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
ion transmembrane transport GO:0034220 361 0.017
germ cell development GO:0007281 185 0.017
glucose homeostasis GO:0042593 128 0.017
response to organic cyclic compound GO:0014070 198 0.017
transmission of nerve impulse GO:0019226 76 0.017
membrane organization GO:0061024 245 0.017
ribonucleoside monophosphate catabolic process GO:0009158 57 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
cellular polysaccharide metabolic process GO:0044264 38 0.017
anion transport GO:0006820 177 0.017
lymphocyte proliferation GO:0046651 164 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
hydrogen ion transmembrane transport GO:1902600 25 0.016
cytokine production GO:0001816 319 0.016
liver development GO:0001889 66 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
amino acid betaine metabolic process GO:0006577 7 0.016
regulation of cell activation GO:0050865 289 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.016
neuronal action potential GO:0019228 54 0.016
ossification GO:0001503 216 0.016
nucleoside catabolic process GO:0009164 206 0.016
lipid modification GO:0030258 65 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
peptide transport GO:0015833 133 0.016
pyridine containing compound metabolic process GO:0072524 14 0.016
regulation of secretion by cell GO:1903530 249 0.016
amide transport GO:0042886 138 0.016
leukocyte differentiation GO:0002521 342 0.015
regulation of cytokine production GO:0001817 266 0.015
regulation of protein kinase activity GO:0045859 232 0.015
maintenance of location GO:0051235 89 0.015
forebrain development GO:0030900 302 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
cell maturation GO:0048469 127 0.015
nucleoside monophosphate catabolic process GO:0009125 59 0.015
regulation of neuron apoptotic process GO:0043523 122 0.015
telencephalon development GO:0021537 186 0.015
response to testosterone GO:0033574 3 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
Yeast
fat cell differentiation GO:0045444 160 0.014
protein homooligomerization GO:0051260 43 0.014
carbohydrate metabolic process GO:0005975 230 0.014
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.014
cellular response to oxidative stress GO:0034599 76 0.014
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.014
response to peptide GO:1901652 136 0.013
oxidoreduction coenzyme metabolic process GO:0006733 16 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
cerebellum development GO:0021549 77 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
metencephalon development GO:0022037 89 0.013
glucan metabolic process GO:0044042 32 0.013
protein maturation GO:0051604 176 0.013
response to oxygen levels GO:0070482 62 0.013
cofactor biosynthetic process GO:0051188 41 0.013
positive regulation of cell death GO:0010942 224 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
Yeast
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
response to reactive oxygen species GO:0000302 56 0.013
response to starvation GO:0042594 65 0.013
pyridine nucleotide metabolic process GO:0019362 12 0.013
positive regulation of mitochondrion organization GO:0010822 17 0.013
negative regulation of cell development GO:0010721 169 0.013
spermatogenesis GO:0007283 284 0.013
negative regulation of molecular function GO:0044092 258 0.013
positive regulation of transferase activity GO:0051347 167 0.013
cellular glucan metabolic process GO:0006073 32 0.013
phagocytosis GO:0006909 66 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
protein transmembrane transport GO:0071806 8 0.012
response to lipopolysaccharide GO:0032496 128 0.012
muscle tissue development GO:0060537 308 0.012
regulation of glucose metabolic process GO:0010906 60 0.012
negative regulation of neuron apoptotic process GO:0043524 92 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
regulation of protein transport GO:0051223 163 0.012
nad metabolic process GO:0019674 7 0.012
protein localization to nucleus GO:0034504 121 0.012
protein processing GO:0016485 163 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
immune effector process GO:0002252 321 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
Yeast
striated muscle tissue development GO:0014706 293 0.012
regulation of cell cycle process GO:0010564 160 0.012
regulation of protein localization GO:0032880 231 0.012
protein catabolic process GO:0030163 221 0.012
myeloid cell homeostasis GO:0002262 114 0.012
anatomical structure homeostasis GO:0060249 145 0.012
leukocyte proliferation GO:0070661 172 0.012
adult behavior GO:0030534 135 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
Yeast
dna metabolic process GO:0006259 303 0.012
ensheathment of neurons GO:0007272 76 0.012
cellular response to lipid GO:0071396 145 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
axon ensheathment GO:0008366 76 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
positive regulation of organelle organization GO:0010638 128 0.011
monocarboxylic acid catabolic process GO:0072329 27 0.011
lymphocyte differentiation GO:0030098 242 0.011
mapk cascade GO:0000165 281 0.011
extracellular matrix organization GO:0030198 147 0.011
endomembrane system organization GO:0010256 147 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
dna catabolic process endonucleolytic GO:0000737 15 0.011
tissue homeostasis GO:0001894 115 0.011
hydrogen transport GO:0006818 35 0.011
t cell differentiation GO:0030217 174 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
aerobic respiration GO:0009060 7 0.011
cell adhesion GO:0007155 329 0.011
dephosphorylation GO:0016311 129 0.011
sensory perception GO:0007600 245 0.011
cellular ion homeostasis GO:0006873 165 0.011
histone modification GO:0016570 159 0.011
regulation of hydrolase activity GO:0051336 246 0.011
cation homeostasis GO:0055080 212 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
locomotory behavior GO:0007626 195 0.011
sensory organ morphogenesis GO:0090596 242 0.011
regulation of mitochondrial membrane potential GO:0051881 17 0.011
positive regulation of growth GO:0045927 104 0.011
t cell activation GO:0042110 289 0.011
negative regulation of neuron death GO:1901215 98 0.011
epithelial cell development GO:0002064 159 0.011
rna processing GO:0006396 105 0.011
iron sulfur cluster assembly GO:0016226 3 0.010
negative regulation of transferase activity GO:0051348 85 0.010
gonad development GO:0008406 141 0.010
neural precursor cell proliferation GO:0061351 121 0.010
negative regulation of protein modification process GO:0031400 163 0.010
response to nutrient levels GO:0031667 109 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
embryonic epithelial tube formation GO:0001838 130 0.010
urogenital system development GO:0001655 261 0.010
regulation of interleukin 8 production GO:0032677 3 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.010
response to endoplasmic reticulum stress GO:0034976 53 0.010
purine containing compound metabolic process GO:0072521 311 0.010
Yeast
protein import into nucleus GO:0006606 95 0.010
regulation of t cell activation GO:0050863 170 0.010
negative regulation of kinase activity GO:0033673 81 0.010
neuron migration GO:0001764 122 0.010
i kappab kinase nf kappab signaling GO:0007249 85 0.010
isoprenoid metabolic process GO:0006720 29 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
Yeast
multicellular organism growth GO:0035264 161 0.010
inflammatory response GO:0006954 244 0.010
cellular response to biotic stimulus GO:0071216 92 0.010

Sdha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.682
inherited metabolic disorder DOID:655 0 0.359
amino acid metabolic disorder DOID:9252 0 0.119
cancer DOID:162 0 0.101
disease of cellular proliferation DOID:14566 0 0.101
organ system cancer DOID:0050686 0 0.061
organic acidemia DOID:0060159 0 0.052
endocrine gland cancer DOID:170 0 0.051
disease of anatomical entity DOID:7 0 0.048
nervous system disease DOID:863 0 0.048
gastrointestinal system cancer DOID:3119 0 0.030
central nervous system disease DOID:331 0 0.023
neurodegenerative disease DOID:1289 0 0.023
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011