Mus musculus

46 known processes

Sdhd

succinate dehydrogenase complex, subunit D, integral membrane protein

(Aliases: 3110001M13Rik,PRO19626,C78570,AVLL5809)

Sdhd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
energy derivation by oxidation of organic compounds GO:0015980 77 0.737
Human
citrate metabolic process GO:0006101 3 0.561
oxidation reduction process GO:0055114 342 0.475
4 hydroxyproline metabolic process GO:0019471 5 0.471
cofactor metabolic process GO:0051186 80 0.411
coenzyme biosynthetic process GO:0009108 23 0.360
mitochondrial transport GO:0006839 36 0.242
sulfur compound metabolic process GO:0006790 100 0.202
mitochondrion organization GO:0007005 134 0.201
monocarboxylic acid metabolic process GO:0032787 191 0.191
cofactor biosynthetic process GO:0051188 41 0.156
generation of precursor metabolites and energy GO:0006091 103 0.152
Human
acyl coa metabolic process GO:0006637 19 0.137
cellular respiration GO:0045333 38 0.128
Human
sulfur compound biosynthetic process GO:0044272 37 0.115
nitrogen compound transport GO:0071705 271 0.110
coenzyme metabolic process GO:0006732 52 0.106
purine containing compound metabolic process GO:0072521 311 0.104
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.099
nucleoside phosphate metabolic process GO:0006753 338 0.095
ribonucleotide biosynthetic process GO:0009260 59 0.088
organonitrogen compound biosynthetic process GO:1901566 192 0.085
succinyl coa metabolic process GO:0006104 1 0.080
tricarboxylic acid metabolic process GO:0072350 5 0.076
dicarboxylic acid metabolic process GO:0043648 18 0.076
purine ribonucleoside metabolic process GO:0046128 241 0.075
ribonucleotide metabolic process GO:0009259 291 0.074
nucleobase containing small molecule metabolic process GO:0055086 352 0.073
cytoplasmic transport GO:0016482 234 0.071
purine nucleoside monophosphate metabolic process GO:0009126 81 0.071
atp metabolic process GO:0046034 75 0.066
cellular amino acid metabolic process GO:0006520 103 0.063
small molecule biosynthetic process GO:0044283 132 0.062
amine metabolic process GO:0009308 45 0.058
nucleoside triphosphate metabolic process GO:0009141 230 0.058
cellular ketone metabolic process GO:0042180 84 0.058
response to oxygen levels GO:0070482 62 0.056
cellular homeostasis GO:0019725 240 0.056
cellular modified amino acid metabolic process GO:0006575 63 0.055
glycosyl compound metabolic process GO:1901657 246 0.053
iron sulfur cluster assembly GO:0016226 3 0.052
nucleoside metabolic process GO:0009116 246 0.050
intrinsic apoptotic signaling pathway GO:0097193 132 0.049
regulation of neuron death GO:1901214 134 0.048
myeloid cell homeostasis GO:0002262 114 0.048
placenta development GO:0001890 140 0.046
purine nucleotide metabolic process GO:0006163 302 0.046
carbohydrate metabolic process GO:0005975 230 0.046
nucleoside monophosphate metabolic process GO:0009123 85 0.045
cell type specific apoptotic process GO:0097285 268 0.045
alpha amino acid metabolic process GO:1901605 59 0.044
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.042
myeloid cell differentiation GO:0030099 233 0.042
neuron apoptotic process GO:0051402 142 0.042
homeostasis of number of cells GO:0048872 210 0.040
cellular amine metabolic process GO:0044106 44 0.039
purine nucleoside metabolic process GO:0042278 241 0.038
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.037
positive regulation of growth GO:0045927 104 0.036
mitochondrial membrane organization GO:0007006 26 0.036
ion transmembrane transport GO:0034220 361 0.036
transmembrane transport GO:0055085 412 0.036
neuron death GO:0070997 154 0.035
neural tube formation GO:0001841 108 0.034
intracellular protein transport GO:0006886 204 0.034
muscle tissue development GO:0060537 308 0.033
anion transport GO:0006820 177 0.033
regulation of membrane potential GO:0042391 192 0.033
quinone metabolic process GO:1901661 7 0.033
membrane organization GO:0061024 245 0.032
regulation of cytoplasmic transport GO:1903649 112 0.031
peptidyl amino acid modification GO:0018193 336 0.030
negative regulation of cell proliferation GO:0008285 296 0.030
cellular lipid metabolic process GO:0044255 323 0.030
nucleotide metabolic process GO:0009117 332 0.030
acetyl coa biosynthetic process GO:0006085 5 0.029
nucleocytoplasmic transport GO:0006913 139 0.029
ribonucleotide catabolic process GO:0009261 208 0.029
response to molecule of bacterial origin GO:0002237 143 0.028
metallo sulfur cluster assembly GO:0031163 3 0.028
thioester metabolic process GO:0035383 19 0.028
ribonucleoside monophosphate metabolic process GO:0009161 80 0.027
striated muscle tissue development GO:0014706 293 0.027
heart morphogenesis GO:0003007 178 0.027
apoptotic signaling pathway GO:0097190 306 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
response to decreased oxygen levels GO:0036293 59 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
ubiquinone biosynthetic process GO:0006744 4 0.026
regulation of neuron apoptotic process GO:0043523 122 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
organic anion transport GO:0015711 137 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
nuclear transport GO:0051169 139 0.026
negative regulation of cellular component organization GO:0051129 194 0.025
acyl coa biosynthetic process GO:0071616 7 0.025
action potential GO:0001508 78 0.024
positive regulation of coagulation GO:0050820 13 0.024
leukocyte differentiation GO:0002521 342 0.024
regulation of cellular amino acid metabolic process GO:0006521 5 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.024
regulation of protein localization GO:0032880 231 0.024
organic acid biosynthetic process GO:0016053 86 0.024
endocytosis GO:0006897 168 0.024
succinate metabolic process GO:0006105 4 0.023
protein targeting GO:0006605 143 0.023
regulation of protein transport GO:0051223 163 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
quinone biosynthetic process GO:1901663 4 0.023
cellular ion homeostasis GO:0006873 165 0.023
gland development GO:0048732 330 0.022
response to oxygen radical GO:0000305 16 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
cation transmembrane transport GO:0098655 266 0.021
regulation of atp biosynthetic process GO:2001169 3 0.021
neural tube development GO:0021915 160 0.021
cellular response to oxygen radical GO:0071450 14 0.021
cardiac chamber development GO:0003205 108 0.021
response to superoxide GO:0000303 16 0.021
regulation of cell activation GO:0050865 289 0.021
regulation of intracellular transport GO:0032386 159 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
nucleobase containing compound transport GO:0015931 27 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
oxidative phosphorylation GO:0006119 14 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
metal ion homeostasis GO:0055065 189 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
embryonic epithelial tube formation GO:0001838 130 0.019
regulation of hormone levels GO:0010817 211 0.019
protein maturation GO:0051604 176 0.019
cofactor transport GO:0051181 4 0.019
positive regulation of protein modification process GO:0031401 299 0.019
age dependent general metabolic decline GO:0007571 3 0.019
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
anatomical structure homeostasis GO:0060249 145 0.019
pigment biosynthetic process GO:0046148 26 0.018
leukocyte proliferation GO:0070661 172 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
apoptotic mitochondrial changes GO:0008637 48 0.018
epithelial tube formation GO:0072175 130 0.018
nucleotide biosynthetic process GO:0009165 78 0.018
water soluble vitamin metabolic process GO:0006767 10 0.017
liver development GO:0001889 66 0.017
inflammatory response GO:0006954 244 0.017
lymphocyte differentiation GO:0030098 242 0.017
regulation of organelle organization GO:0033043 289 0.017
lymphocyte proliferation GO:0046651 164 0.017
age dependent response to oxidative stress GO:0001306 3 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
tetrapyrrole metabolic process GO:0033013 22 0.017
regulation of lymphocyte differentiation GO:0045619 107 0.016
regulation of response to wounding GO:1903034 189 0.016
peptidyl proline hydroxylation GO:0019511 3 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
regulation of protein localization to nucleus GO:1900180 60 0.016
natural killer cell mediated cytotoxicity GO:0042267 29 0.016
water soluble vitamin biosynthetic process GO:0042364 3 0.015
calcium ion homeostasis GO:0055074 127 0.015
response to lipopolysaccharide GO:0032496 128 0.015
substantia nigra development GO:0021762 2 0.015
t cell differentiation GO:0030217 174 0.015
aromatic compound catabolic process GO:0019439 286 0.015
negative regulation of immune system process GO:0002683 209 0.015
regulation of ion transport GO:0043269 215 0.015
regulation of t cell activation GO:0050863 170 0.015
cellular chemical homeostasis GO:0055082 215 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
cardiac muscle tissue development GO:0048738 130 0.015
purine nucleotide biosynthetic process GO:0006164 65 0.015
extracellular matrix organization GO:0030198 147 0.015
removal of superoxide radicals GO:0019430 12 0.015
negative regulation of t cell activation GO:0050868 65 0.015
regulation of angiogenesis GO:0045765 81 0.015
regulation of protein kinase activity GO:0045859 232 0.015
regulation of protein targeting GO:1903533 61 0.014
blood vessel morphogenesis GO:0048514 285 0.014
monocarboxylic acid biosynthetic process GO:0072330 61 0.014
cellular amide metabolic process GO:0043603 58 0.014
ribose phosphate biosynthetic process GO:0046390 59 0.014
cytokine production GO:0001816 319 0.014
purine containing compound biosynthetic process GO:0072522 70 0.014
negative regulation of cell activation GO:0050866 111 0.014
epithelial cell proliferation GO:0050673 174 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.014
purine ribonucleoside biosynthetic process GO:0046129 19 0.014
t cell activation GO:0042110 289 0.014
positive regulation of kinase activity GO:0033674 155 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
extracellular structure organization GO:0043062 148 0.014
determination of adult lifespan GO:0008340 11 0.014
Worm
cellular metal ion homeostasis GO:0006875 151 0.014
alcohol metabolic process GO:0006066 116 0.014
male sex differentiation GO:0046661 109 0.014
pyruvate metabolic process GO:0006090 28 0.014
angiogenesis GO:0001525 201 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
dna catabolic process endonucleolytic GO:0000737 15 0.013
trabecula morphogenesis GO:0061383 40 0.013
cellular response to extracellular stimulus GO:0031668 81 0.013
response to oxidative stress GO:0006979 123 0.013
tissue homeostasis GO:0001894 115 0.013
tetrapyrrole biosynthetic process GO:0033014 16 0.013
leukocyte mediated immunity GO:0002443 174 0.013
regulation of transmembrane transport GO:0034762 128 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
regulation of kinase activity GO:0043549 249 0.013
cardiac chamber morphogenesis GO:0003206 93 0.013
regulation of cell growth GO:0001558 91 0.013
cardiac ventricle development GO:0003231 83 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
cardiac septum development GO:0003279 59 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
synaptic transmission GO:0007268 329 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
response to inorganic substance GO:0010035 96 0.013
protein localization to organelle GO:0033365 185 0.012
cellular response to lipid GO:0071396 145 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
blood coagulation GO:0007596 76 0.012
divalent metal ion transport GO:0070838 172 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
fatty acid metabolic process GO:0006631 121 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
hydrogen ion transmembrane transport GO:1902600 25 0.012
skeletal system development GO:0001501 356 0.012
cation homeostasis GO:0055080 212 0.012
regulation of vasculature development GO:1901342 88 0.012
multi multicellular organism process GO:0044706 109 0.012
adult behavior GO:0030534 135 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
aerobic respiration GO:0009060 7 0.012
Human
cellular response to molecule of bacterial origin GO:0071219 83 0.012
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.012
tube formation GO:0035148 140 0.012
signal transduction in absence of ligand GO:0038034 55 0.012
regulation of map kinase activity GO:0043405 120 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
sequestering of metal ion GO:0051238 19 0.012
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
negative regulation of cell development GO:0010721 169 0.011
heme metabolic process GO:0042168 16 0.011
sensory perception GO:0007600 245 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
cation transport GO:0006812 399 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
regulation of mapk cascade GO:0043408 248 0.011
wound healing GO:0042060 157 0.011
glycosyl compound biosynthetic process GO:1901659 21 0.011
glucose homeostasis GO:0042593 128 0.011
thioester biosynthetic process GO:0035384 7 0.011
divalent inorganic cation transport GO:0072511 178 0.011
lipid localization GO:0010876 126 0.011
regulation of blood coagulation GO:0030193 28 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
atp synthesis coupled electron transport GO:0042773 8 0.011
negative regulation of organelle organization GO:0010639 90 0.011
lipid biosynthetic process GO:0008610 179 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
regulation of cytokine production GO:0001817 266 0.011
protein export from nucleus GO:0006611 20 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
forebrain development GO:0030900 302 0.011
ventricular septum development GO:0003281 42 0.011
vitamin metabolic process GO:0006766 23 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
respiratory system development GO:0060541 190 0.010
nadh metabolic process GO:0006734 1 0.010
protein oxidation GO:0018158 2 0.010
negative regulation of nervous system development GO:0051961 156 0.010
mapk cascade GO:0000165 281 0.010
organelle localization GO:0051640 179 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
regulation of male germ cell proliferation GO:2000254 3 0.010
oxidoreduction coenzyme metabolic process GO:0006733 16 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010

Sdhd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.161
Human
disease of metabolism DOID:0014667 0 0.056
gastrointestinal system cancer DOID:3119 0 0.040
cancer DOID:162 0 0.040
Human
organ system cancer DOID:0050686 0 0.040
Human
inherited metabolic disorder DOID:655 0 0.040
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
endocrine gland cancer DOID:170 0 0.012
Human
phaeochromocytoma DOID:0050771 0 0.011
Human
cell type benign neoplasm DOID:0060084 0 0.011
Human
benign neoplasm DOID:0060072 0 0.011
Human