Mus musculus

0 known processes

Sec61a1

Sec61 alpha 1 subunit (S. cerevisiae)

(Aliases: AA410007,AA408394,Sec61a)

Sec61a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glycoprotein metabolic process GO:0009100 116 0.559
protein glycosylation GO:0006486 55 0.423
protein n linked glycosylation GO:0006487 12 0.374
glycosylation GO:0070085 62 0.332
glycoprotein biosynthetic process GO:0009101 89 0.261
endoplasmic reticulum unfolded protein response GO:0030968 19 0.181
carbohydrate metabolic process GO:0005975 230 0.154
response to unfolded protein GO:0006986 21 0.144
carbohydrate derivative biosynthetic process GO:1901137 183 0.133
macromolecule glycosylation GO:0043413 55 0.122
peptidyl proline hydroxylation GO:0019511 3 0.117
cellular amine metabolic process GO:0044106 44 0.106
cation transport GO:0006812 399 0.099
Fly
copii coated vesicle budding GO:0090114 2 0.099
response to endoplasmic reticulum stress GO:0034976 53 0.088
er nucleus signaling pathway GO:0006984 27 0.085
cellular response to topologically incorrect protein GO:0035967 25 0.084
positive regulation of endocytosis GO:0045807 42 0.073
gland development GO:0048732 330 0.071
ion transmembrane transport GO:0034220 361 0.070
Fly
skeletal system development GO:0001501 356 0.070
regulation of cellular amine metabolic process GO:0033238 20 0.066
hepaticobiliary system development GO:0061008 67 0.062
response to topologically incorrect protein GO:0035966 25 0.061
proteasomal protein catabolic process GO:0010498 98 0.061
protein hydroxylation GO:0018126 4 0.060
leukocyte differentiation GO:0002521 342 0.060
endomembrane system organization GO:0010256 147 0.055
Human
male gamete generation GO:0048232 285 0.053
regulation of phagocytosis GO:0050764 33 0.047
transmembrane transport GO:0055085 412 0.046
Fly
cation transmembrane transport GO:0098655 266 0.045
Fly
localization within membrane GO:0051668 4 0.043
liver development GO:0001889 66 0.043
maintenance of location GO:0051235 89 0.043
cellular chemical homeostasis GO:0055082 215 0.043
intra golgi vesicle mediated transport GO:0006891 1 0.042
inorganic ion transmembrane transport GO:0098660 234 0.040
Fly
cellular macromolecule catabolic process GO:0044265 206 0.040
translation GO:0006412 93 0.039
response to hypoxia GO:0001666 58 0.039
nucleotide sugar metabolic process GO:0009225 4 0.038
cytoplasmic transport GO:0016482 234 0.038
Human Yeast
cellular response to zinc ion starvation GO:0034224 2 0.038
membrane organization GO:0061024 245 0.037
Human Yeast
positive regulation of apoptotic cell clearance GO:2000427 3 0.037
regulation of translation GO:0006417 71 0.036
peptidyl asparagine modification GO:0018196 1 0.036
spermatogenesis GO:0007283 284 0.036
peptidyl proline hydroxylation to 4 hydroxy l proline GO:0018401 2 0.035
response to oxygen levels GO:0070482 62 0.035
cellular amino acid metabolic process GO:0006520 103 0.034
lateral inhibition GO:0046331 1 0.032
t cell activation GO:0042110 289 0.032
cellular response to lipid GO:0071396 145 0.031
peptidyl proline modification GO:0018208 6 0.031
cellular response to molecule of bacterial origin GO:0071219 83 0.031
amine metabolic process GO:0009308 45 0.031
cellular transition metal ion homeostasis GO:0046916 32 0.030
regulation of vesicle mediated transport GO:0060627 139 0.030
lymphocyte differentiation GO:0030098 242 0.029
t cell differentiation GO:0030217 174 0.028
stem cell differentiation GO:0048863 268 0.028
regulation of t cell activation GO:0050863 170 0.028
nucleotide transmembrane transport GO:1901679 2 0.027
glucose homeostasis GO:0042593 128 0.026
regulation of lymphocyte differentiation GO:0045619 107 0.026
body morphogenesis GO:0010171 45 0.026
connective tissue development GO:0061448 179 0.025
macromolecule catabolic process GO:0009057 281 0.024
cellular response to misfolded protein GO:0071218 5 0.024
positive regulation of interleukin 6 secretion GO:2000778 1 0.024
endocytosis GO:0006897 168 0.023
cation homeostasis GO:0055080 212 0.023
multicellular organism growth GO:0035264 161 0.023
spermatid differentiation GO:0048515 115 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
phagocytosis GO:0006909 66 0.022
immune effector process GO:0002252 321 0.021
regulation of t cell differentiation GO:0045580 83 0.021
regulation of cell activation GO:0050865 289 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
cartilage development GO:0051216 140 0.021
divalent inorganic cation transport GO:0072511 178 0.021
oxidation reduction process GO:0055114 342 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.021
rna processing GO:0006396 105 0.020
mrna processing GO:0006397 63 0.020
interleukin 6 secretion GO:0072604 3 0.020
vascular process in circulatory system GO:0003018 62 0.020
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.020
germ cell development GO:0007281 185 0.019
cellular response to biotic stimulus GO:0071216 92 0.019
renal system development GO:0072001 225 0.019
regulation of actin nucleation GO:0051125 4 0.019
muscle cell differentiation GO:0042692 261 0.019
dephosphorylation GO:0016311 129 0.019
positive regulation of lymphocyte activation GO:0051251 140 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
regulation of cytokine production GO:0001817 266 0.018
protein localization to organelle GO:0033365 185 0.018
Human Yeast
inter male aggressive behavior GO:0002121 3 0.018
positive regulation of phagocytosis GO:0050766 26 0.018
organism emergence from protective structure GO:0071684 4 0.018
negative regulation of nervous system development GO:0051961 156 0.017
regulation of cytokine secretion GO:0050707 61 0.017
positive regulation of cell activation GO:0050867 158 0.017
protein n linked glycosylation via asparagine GO:0018279 1 0.017
stem cell development GO:0048864 219 0.017
acetylcholine transport GO:0015870 2 0.017
compound eye development GO:0048749 1 0.017
steroid metabolic process GO:0008202 119 0.017
regulation of double strand break repair via nonhomologous end joining GO:2001032 2 0.017
transition metal ion homeostasis GO:0055076 54 0.017
protein folding GO:0006457 28 0.016
lymphocyte activation involved in immune response GO:0002285 93 0.016
bone development GO:0060348 120 0.016
golgi vesicle transport GO:0048193 30 0.016
dna metabolic process GO:0006259 303 0.016
response to acid chemical GO:0001101 111 0.016
regulation of cellular ketone metabolic process GO:0010565 66 0.016
protein catabolic process GO:0030163 221 0.016
response to lipopolysaccharide GO:0032496 128 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
cellular lipid metabolic process GO:0044255 323 0.015
peptidyl amino acid modification GO:0018193 336 0.015
regulation of endocytosis GO:0030100 69 0.015
circulatory system process GO:0003013 197 0.015
cellular ion homeostasis GO:0006873 165 0.015
digestive system development GO:0055123 200 0.015
regulation of cell projection organization GO:0031344 206 0.015
response to organic cyclic compound GO:0014070 198 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
regulation of secretion by cell GO:1903530 249 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
b cell activation GO:0042113 161 0.015
cellular protein complex assembly GO:0043623 116 0.014
regulation of lipid storage GO:0010883 20 0.014
regulation of mrna metabolic process GO:1903311 43 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
metal ion homeostasis GO:0055065 189 0.014
regulation of interleukin 8 production GO:0032677 3 0.014
chromatin organization GO:0006325 206 0.014
regulation of tube size GO:0035150 57 0.014
protein ubiquitination GO:0016567 171 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
regulation of neuron differentiation GO:0045664 281 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
Fly
mrna metabolic process GO:0016071 84 0.014
organic anion transport GO:0015711 137 0.014
cellular response to external stimulus GO:0071496 88 0.014
meiotic cell cycle GO:0051321 122 0.013
neural crest cell development GO:0014032 48 0.013
carbohydrate homeostasis GO:0033500 128 0.013
arp2 3 complex mediated actin nucleation GO:0034314 3 0.013
urogenital system development GO:0001655 261 0.013
cell activation involved in immune response GO:0002263 126 0.013
regulation of mrna splicing via spliceosome GO:0048024 32 0.013
positive regulation of vasoconstriction GO:0045907 4 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
er to golgi vesicle mediated transport GO:0006888 11 0.013
heart morphogenesis GO:0003007 178 0.013
catecholamine metabolic process GO:0006584 30 0.013
hatching GO:0035188 4 0.013
positive regulation of cellular protein catabolic process GO:1903364 34 0.013
cytokine production GO:0001816 319 0.013
embryonic skeletal system development GO:0048706 120 0.013
t helper 2 cell cytokine production GO:0035745 4 0.013
mitotic cytokinesis GO:0000281 4 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
cell adhesion GO:0007155 329 0.012
actin cytoskeleton organization GO:0030036 220 0.012
positive regulation of growth GO:0045927 104 0.012
mitotic cell cycle GO:0000278 195 0.012
response to radiation GO:0009314 165 0.012
blood circulation GO:0008015 195 0.012
dna recombination GO:0006310 92 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
cytokine secretion GO:0050663 72 0.012
nuclear membrane organization GO:0071763 4 0.012
multi multicellular organism process GO:0044706 109 0.012
lipid localization GO:0010876 126 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
Fly
reactive oxygen species metabolic process GO:0072593 84 0.012
regulation of anatomical structure size GO:0090066 178 0.012
rho protein signal transduction GO:0007266 32 0.012
adult behavior GO:0030534 135 0.012
response to estrogen GO:0043627 24 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
regulation of hormone levels GO:0010817 211 0.011
regulation of notch signaling pathway GO:0008593 35 0.011
neural tube development GO:0021915 160 0.011
negative regulation of cell projection organization GO:0031345 56 0.011
t cell differentiation in thymus GO:0033077 77 0.011
negative regulation of cell cycle GO:0045786 123 0.011
vesicle organization GO:0016050 60 0.011
protein secretion GO:0009306 111 0.011
regulation of cell adhesion GO:0030155 154 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
regulation of heart contraction GO:0008016 77 0.011
regulation of stem cell differentiation GO:2000736 50 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
midgut development GO:0007494 4 0.011
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.011
rna splicing GO:0008380 54 0.011
lipid biosynthetic process GO:0008610 179 0.011
meiotic nuclear division GO:0007126 115 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
spermatid development GO:0007286 108 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.010
lateral line system development GO:0048925 1 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
regulation of mrna processing GO:0050684 41 0.010
skeletal system morphogenesis GO:0048705 203 0.010
positive regulation of blood circulation GO:1903524 22 0.010
negative regulation of organelle organization GO:0010639 90 0.010
positive regulation of immune effector process GO:0002699 107 0.010
extracellular matrix organization GO:0030198 147 0.010
regulation of cell cycle GO:0051726 281 0.010
immunoglobulin production GO:0002377 73 0.010

Sec61a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
nervous system disease DOID:863 0 0.051
neuropathy DOID:870 0 0.051
musculoskeletal system disease DOID:17 0 0.029
bone development disease DOID:0080006 0 0.029
bone disease DOID:0080001 0 0.029
connective tissue disease DOID:65 0 0.029
osteochondrodysplasia DOID:2256 0 0.029
muscle tissue disease DOID:66 0 0.027
myopathy DOID:423 0 0.027
limb girdle muscular dystrophy DOID:11724 0 0.027
muscular dystrophy DOID:9884 0 0.027
muscular disease DOID:0080000 0 0.027
organ system cancer DOID:0050686 0 0.024
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
immune system cancer DOID:0060083 0 0.021
central nervous system disease DOID:331 0 0.012
osteogenesis imperfecta DOID:12347 0 0.011
neurodegenerative disease DOID:1289 0 0.011