Mus musculus

76 known processes

Selp

selectin, platelet

(Aliases: PADGEM,MGC129336,MGC129337,CD62P,Grmp,GMP-140,LECAM3)

Selp biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
granulocyte chemotaxis GO:0071621 39 0.994
immune effector process GO:0002252 321 0.990
inflammatory response GO:0006954 244 0.987
neutrophil migration GO:1990266 37 0.983
leukocyte migration GO:0050900 124 0.979
granulocyte migration GO:0097530 43 0.978
myeloid leukocyte migration GO:0097529 57 0.977
positive regulation of neutrophil chemotaxis GO:0090023 12 0.974
neutrophil chemotaxis GO:0030593 36 0.971
regulation of neutrophil chemotaxis GO:0090022 14 0.962
regulation of response to wounding GO:1903034 189 0.956
leukocyte chemotaxis GO:0030595 69 0.956
positive regulation of defense response GO:0031349 124 0.953
positive regulation of monocyte chemotaxis GO:0090026 2 0.950
cell chemotaxis GO:0060326 81 0.946
positive regulation of neutrophil migration GO:1902624 12 0.927
negative regulation of macrophage apoptotic process GO:2000110 3 0.926
regulation of blood coagulation GO:0030193 28 0.919
positive regulation of granulocyte chemotaxis GO:0071624 12 0.916
defense response to other organism GO:0098542 197 0.906
regulation of cell activation GO:0050865 289 0.895
positive regulation of cytokine production GO:0001819 174 0.888
positive regulation of response to wounding GO:1903036 66 0.882
cellular extravasation GO:0045123 17 0.868
t cell proliferation GO:0042098 120 0.865
t cell extravasation GO:0072683 4 0.854
eosinophil activation involved in immune response GO:0002278 1 0.853
g protein coupled receptor signaling pathway GO:0007186 243 0.852
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.848
positive regulation of immunological synapse formation GO:2000522 1 0.840
regulation of neutrophil migration GO:1902622 14 0.835
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 20 0.830
single organismal cell cell adhesion GO:0016337 131 0.811
vascular endothelial growth factor production GO:0010573 13 0.809
blood vessel morphogenesis GO:0048514 285 0.804
Rat
cellular response to cytokine stimulus GO:0071345 189 0.793
blood coagulation GO:0007596 76 0.790
positive regulation of chemotaxis GO:0050921 38 0.789
positive regulation of endocytosis GO:0045807 42 0.774
chemotaxis GO:0006935 247 0.772
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.770
leukocyte cell cell adhesion GO:0007159 14 0.767
regulation of inflammatory response GO:0050727 147 0.764
regulation of granulocyte chemotaxis GO:0071622 17 0.761
regulation of monocyte chemotaxis GO:0090025 3 0.757
regulation of angiogenesis GO:0045765 81 0.757
defense response to bacterium GO:0042742 119 0.748
immune complex clearance GO:0002434 2 0.745
positive regulation of cell motility GO:2000147 116 0.743
positive regulation of angiogenesis GO:0045766 46 0.740
positive regulation of inflammatory response GO:0050729 47 0.733
extrinsic apoptotic signaling pathway GO:0097191 126 0.731
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.721
cytokine secretion GO:0050663 72 0.720
positive regulation of t cell costimulation GO:2000525 2 0.719
t cell activation GO:0042110 289 0.718
cytokine mediated signaling pathway GO:0019221 115 0.712
regulation of leukocyte mediated immunity GO:0002703 104 0.710
regulation of vesicle mediated transport GO:0060627 139 0.692
myeloid leukocyte activation GO:0002274 83 0.691
regulation of dendritic cell chemotaxis GO:2000508 1 0.665
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.664
regulation of cell motility GO:2000145 236 0.659
positive regulation of hemostasis GO:1900048 10 0.652
regulation of chemokine production GO:0032642 30 0.647
cytokine production GO:0001816 319 0.642
leukocyte activation involved in immune response GO:0002366 126 0.639
regulation of adaptive immune response GO:0002819 90 0.633
helper t cell chemotaxis GO:0035704 1 0.626
myotube differentiation GO:0014902 105 0.605
positive regulation of coagulation GO:0050820 13 0.600
interleukin 18 mediated signaling pathway GO:0035655 2 0.598
positive regulation of t cell extravasation GO:2000409 2 0.595
interleukin 12 secretion GO:0072610 3 0.595
regulation of defense response GO:0031347 233 0.591
regulation of platelet activation GO:0010543 17 0.579
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.573
positive regulation of wound healing GO:0090303 17 0.566
negative regulation of immune system process GO:0002683 209 0.558
regulation of endocytosis GO:0030100 69 0.550
positive regulation of cell migration GO:0030335 109 0.548
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.533
regulation of t helper 1 type immune response GO:0002825 17 0.532
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.532
acute inflammatory response GO:0002526 41 0.532
ameboidal type cell migration GO:0001667 128 0.531
carbohydrate derivative biosynthetic process GO:1901137 183 0.525
negative regulation of intracellular signal transduction GO:1902532 167 0.523
positive regulation of behavior GO:0048520 40 0.519
angiogenesis GO:0001525 201 0.515
sphingolipid metabolic process GO:0006665 45 0.513
regulation of rho protein signal transduction GO:0035023 71 0.510
cell activation involved in immune response GO:0002263 126 0.506
positive regulation of cell activation GO:0050867 158 0.505
positive regulation of platelet activation GO:0010572 5 0.501
regulation of t cell extravasation GO:2000407 3 0.496
response to organic cyclic compound GO:0014070 198 0.496
Mouse Rat
inflammatory response to wounding GO:0090594 4 0.494
regulation of vasculature development GO:1901342 88 0.491
regulation of homeostatic process GO:0032844 182 0.472
macrophage chemotaxis GO:0048246 14 0.469
regulation of t cell costimulation GO:2000523 2 0.465
positive regulation of macrophage activation GO:0043032 10 0.465
positive regulation of apoptotic process GO:0043065 217 0.462
keratinocyte migration GO:0051546 3 0.457
skeletal muscle organ development GO:0060538 163 0.450
negative regulation of cell activation GO:0050866 111 0.449
antibacterial peptide biosynthetic process GO:0002780 2 0.447
regulation of lymphocyte activation GO:0051249 240 0.444
myeloid cell differentiation GO:0030099 233 0.444
response to hyperoxia GO:0055093 2 0.444
regulation of monocyte extravasation GO:2000437 2 0.444
t helper 2 cell cytokine production GO:0035745 4 0.438
regulation of cytokine production GO:0001817 266 0.437
lymphocyte mediated immunity GO:0002449 139 0.428
regulation of leukocyte proliferation GO:0070663 121 0.427
regulation of body fluid levels GO:0050878 162 0.426
wound healing GO:0042060 157 0.425
membrane organization GO:0061024 245 0.424
t helper cell differentiation GO:0042093 28 0.414
lymphocyte migration GO:0072676 26 0.413
regulation of coagulation GO:0050818 31 0.412
muscle cell differentiation GO:0042692 261 0.411
negative regulation of adaptive immune response GO:0002820 25 0.410
t helper 17 cell chemotaxis GO:0035705 1 0.409
cytokine biosynthetic process GO:0042089 68 0.407
regulation of secretion GO:0051046 274 0.405
sequestering of metal ion GO:0051238 19 0.403
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.395
epithelial cell proliferation GO:0050673 174 0.390
regulation of type 2 immune response GO:0002828 18 0.390
cell cell adhesion GO:0098609 41 0.389
amine metabolic process GO:0009308 45 0.389
regulation of cytokine secretion GO:0050707 61 0.387
leukocyte differentiation GO:0002521 342 0.387
negative regulation of eosinophil degranulation GO:0043310 1 0.385
immune complex clearance by monocytes and macrophages GO:0002436 2 0.383
leukocyte mediated immunity GO:0002443 174 0.382
adaptive immune response GO:0002250 155 0.381
t cell migration GO:0072678 19 0.381
positive regulation of monocyte extravasation GO:2000439 1 0.381
b cell mediated immunity GO:0019724 71 0.379
apoptotic signaling pathway GO:0097190 306 0.375
lymphocyte proliferation GO:0046651 164 0.373
regulation of b cell mediated immunity GO:0002712 37 0.372
mature dendritic cell differentiation GO:0097029 3 0.368
microglial cell activation involved in immune response GO:0002282 1 0.368
eosinophil degranulation GO:0043308 1 0.359
humoral immune response GO:0006959 57 0.356
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.355
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.351
positive regulation of phagocytosis GO:0050766 26 0.350
regulation of chemotaxis GO:0050920 53 0.350
cholesterol metabolic process GO:0008203 56 0.350
regulation of chemokine secretion GO:0090196 4 0.347
cell killing GO:0001906 67 0.346
regulation of protein localization GO:0032880 231 0.346
immune response activating signal transduction GO:0002757 116 0.344
regulation of vascular endothelial growth factor production GO:0010574 13 0.343
regulation of phospholipase c activity GO:1900274 3 0.342
cellular calcium ion homeostasis GO:0006874 119 0.340
eosinophil activation GO:0043307 1 0.339
rho protein signal transduction GO:0007266 32 0.336
antibacterial peptide secretion GO:0002779 1 0.336
leukocyte proliferation GO:0070661 172 0.333
regulation of hematopoietic stem cell migration GO:2000471 1 0.331
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.319
positive regulation of hydrolase activity GO:0051345 148 0.316
regulation of acute inflammatory response GO:0002673 27 0.316
cellular response to growth factor stimulus GO:0071363 197 0.314
eosinophil mediated immunity GO:0002447 1 0.314
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.313
alpha beta t cell proliferation GO:0046633 21 0.311
regulation of lymphocyte proliferation GO:0050670 117 0.311
second messenger mediated signaling GO:0019932 73 0.306
cellular response to interleukin 18 GO:0071351 3 0.305
cellular amine metabolic process GO:0044106 44 0.301
regulation of cell migration GO:0030334 219 0.299
regulation of antigen processing and presentation GO:0002577 10 0.298
response to growth factor GO:0070848 198 0.297
gliogenesis GO:0042063 141 0.297
signal transduction in absence of ligand GO:0038034 55 0.296
regulation of epithelial cell proliferation GO:0050678 141 0.295
organ or tissue specific immune response GO:0002251 13 0.294
response to oxygen levels GO:0070482 62 0.291
positive regulation of acute inflammatory response GO:0002675 16 0.289
response to organonitrogen compound GO:0010243 246 0.288
Mouse
leukocyte homeostasis GO:0001776 79 0.288
regulation of phagocytosis GO:0050764 33 0.284
release of sequestered calcium ion into cytosol GO:0051209 42 0.283
positive regulation of secretion GO:0051047 130 0.282
positive regulation of leukocyte proliferation GO:0070665 73 0.282
syncytium formation by plasma membrane fusion GO:0000768 42 0.281
cellular ketone metabolic process GO:0042180 84 0.281
ras protein signal transduction GO:0007265 77 0.277
chemokine mediated signaling pathway GO:0070098 17 0.276
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.274
nitrogen compound transport GO:0071705 271 0.270
response to interleukin 1 GO:0070555 11 0.268
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.265
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.262
fat cell differentiation GO:0045444 160 0.262
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.261
regulation of cellular ketone metabolic process GO:0010565 66 0.260
organonitrogen compound biosynthetic process GO:1901566 192 0.256
cd4 positive alpha beta t cell activation GO:0035710 45 0.252
regulation of cellular amino acid metabolic process GO:0006521 5 0.248
positive regulation of immune effector process GO:0002699 107 0.246
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.245
positive regulation of macrophage chemotaxis GO:0010759 5 0.244
response to molecule of bacterial origin GO:0002237 143 0.236
Rat
regulation of interleukin 12 production GO:0032655 30 0.236
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.236
regulation of regulated secretory pathway GO:1903305 20 0.235
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.235
positive regulation of nervous system development GO:0051962 221 0.235
interleukin 1 secretion GO:0050701 16 0.234
ribonucleotide metabolic process GO:0009259 291 0.234
monocyte extravasation GO:0035696 2 0.230
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.228
kidney development GO:0001822 213 0.227
positive regulation of type 2 immune response GO:0002830 9 0.227
ribose phosphate metabolic process GO:0019693 291 0.226
homeostasis of number of cells GO:0048872 210 0.225
innate immune response GO:0045087 157 0.223
jnk cascade GO:0007254 72 0.220
positive regulation of tumor necrosis factor production GO:0032760 30 0.219
inflammatory response to antigenic stimulus GO:0002437 30 0.218
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.217
response to decreased oxygen levels GO:0036293 59 0.216
cytosolic calcium ion transport GO:0060401 48 0.214
muscle tissue development GO:0060537 308 0.214
leukocyte mediated cytotoxicity GO:0001909 62 0.212
interleukin 12 production GO:0032615 32 0.211
negative regulation of phagocytosis GO:0050765 4 0.208
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.206
cell adhesion GO:0007155 329 0.204
leukocyte apoptotic process GO:0071887 71 0.203
negative regulation of inflammatory response GO:0050728 61 0.203
regulation of protein secretion GO:0050708 82 0.202
interspecies interaction between organisms GO:0044419 83 0.200
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.199
response to organophosphorus GO:0046683 22 0.199
Mouse
positive regulation of cytokine secretion GO:0050715 41 0.198
response to atp GO:0033198 8 0.198
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.197
regulation of interleukin 1 production GO:0032652 26 0.194
defense response to gram positive bacterium GO:0050830 50 0.192
dendritic cell chemotaxis GO:0002407 7 0.192
positive regulation of b cell chemotaxis GO:2000538 2 0.191
negative regulation of rho protein signal transduction GO:0035024 7 0.190
cellular amino acid metabolic process GO:0006520 103 0.190
microglial cell activation GO:0001774 3 0.189
wound healing involved in inflammatory response GO:0002246 4 0.189
regulation of hypersensitivity GO:0002883 10 0.186
nucleoside phosphate metabolic process GO:0006753 338 0.186
neutrophil mediated killing of fungus GO:0070947 3 0.185
purine containing compound metabolic process GO:0072521 311 0.184
regulation of hydrolase activity GO:0051336 246 0.184
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.182
striated muscle cell development GO:0055002 125 0.182
single organism cell adhesion GO:0098602 156 0.181
lymphocyte differentiation GO:0030098 242 0.181
myeloid cell activation involved in immune response GO:0002275 34 0.181
ceramide metabolic process GO:0006672 31 0.180
myeloid leukocyte mediated immunity GO:0002444 42 0.179
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.178
positive regulation of protein modification process GO:0031401 299 0.176
chemokine production GO:0032602 34 0.176
immunoglobulin mediated immune response GO:0016064 69 0.175
lymphocyte activation involved in immune response GO:0002285 93 0.175
regulation of cellular amine metabolic process GO:0033238 20 0.174
hemostasis GO:0007599 78 0.174
neuronal action potential GO:0019228 54 0.174
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.171
t helper 1 type immune response GO:0042088 25 0.170
interleukin 1 production GO:0032612 31 0.170
regulation of organelle organization GO:0033043 289 0.169
germ cell development GO:0007281 185 0.168
production of molecular mediator of immune response GO:0002440 103 0.167
regulation of transferase activity GO:0051338 263 0.167
t cell differentiation GO:0030217 174 0.165
response to acid chemical GO:0001101 111 0.165
interleukin 1 beta production GO:0032611 30 0.164
sequestering of calcium ion GO:0051208 18 0.163
positive regulation of intracellular transport GO:0032388 70 0.162
t cell mediated immunity GO:0002456 50 0.162
regulation of actin cytoskeleton organization GO:0032956 84 0.161
positive regulation of leukocyte differentiation GO:1902107 86 0.161
response to endoplasmic reticulum stress GO:0034976 53 0.160
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.160
acute inflammatory response to antigenic stimulus GO:0002438 12 0.160
positive regulation of protein transport GO:0051222 93 0.159
negative regulation of cell proliferation GO:0008285 296 0.159
regulation of hemostasis GO:1900046 28 0.159
response to purine containing compound GO:0014074 28 0.159
Mouse
protein secretion GO:0009306 111 0.159
aromatic compound catabolic process GO:0019439 286 0.158
reactive oxygen species metabolic process GO:0072593 84 0.157
response to increased oxygen levels GO:0036296 2 0.157
regulation of interleukin 1 secretion GO:0050704 15 0.157
inflammatory cell apoptotic process GO:0006925 11 0.157
regulation of secretion by cell GO:1903530 249 0.157
calcium ion transport into cytosol GO:0060402 48 0.155
cellular response to tumor necrosis factor GO:0071356 21 0.155
negative regulation of protein metabolic process GO:0051248 282 0.154
regulation of reactive oxygen species metabolic process GO:2000377 40 0.153
divalent inorganic cation homeostasis GO:0072507 138 0.153
dna metabolic process GO:0006259 303 0.153
regulation of cellular component biogenesis GO:0044087 181 0.153
Human
endocytosis GO:0006897 168 0.152
stress activated mapk cascade GO:0051403 80 0.152
positive regulation of epithelial cell proliferation GO:0050679 68 0.152
cellular lipid metabolic process GO:0044255 323 0.151
hematopoietic stem cell migration GO:0035701 1 0.151
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.151
immunoglobulin production GO:0002377 73 0.150
regulation of natural killer cell chemotaxis GO:2000501 1 0.150
innate immune response in mucosa GO:0002227 3 0.150
positive regulation of protein secretion GO:0050714 52 0.150
regulation of peptidase activity GO:0052547 96 0.149
alpha beta t cell activation GO:0046631 91 0.149
response to hypoxia GO:0001666 58 0.148
positive regulation of myotube differentiation GO:0010831 24 0.148
regulation of eosinophil degranulation GO:0043309 1 0.147
t helper 1 cell differentiation GO:0045063 13 0.146
negative regulation of cytokine production GO:0001818 84 0.146
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.146
response to lipopolysaccharide GO:0032496 128 0.145
Rat
regulation of protein transport GO:0051223 163 0.145
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.145
gland development GO:0048732 330 0.145
cytoplasmic transport GO:0016482 234 0.144
positive regulation of leukocyte mediated immunity GO:0002705 70 0.144
glial cell differentiation GO:0010001 131 0.144
cdc42 protein signal transduction GO:0032488 0 0.143
myeloid cell apoptotic process GO:0033028 22 0.143
negative regulation of response to wounding GO:1903035 77 0.143
regulation of establishment of protein localization GO:0070201 181 0.142
axon guidance GO:0007411 141 0.142
regulation of wound healing GO:0061041 40 0.139
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.139
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.137
dendritic cell dendrite assembly GO:0097026 2 0.136
cytokine production involved in immune response GO:0002367 34 0.136
negative regulation of defense response GO:0031348 77 0.135
stress activated protein kinase signaling cascade GO:0031098 81 0.134
eosinophil migration GO:0072677 3 0.134
regulation of interleukin 1 beta secretion GO:0050706 15 0.133
response to tumor necrosis factor GO:0034612 26 0.133
cytokine metabolic process GO:0042107 71 0.132
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.132
negative regulation of cell migration GO:0030336 59 0.132
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.131
cellular defense response GO:0006968 6 0.131
cell type specific apoptotic process GO:0097285 268 0.130
purine ribonucleoside metabolic process GO:0046128 241 0.130
negative regulation of angiogenesis GO:0016525 25 0.129
regulation of immunoglobulin mediated immune response GO:0002889 37 0.129
positive regulation of cellular amine metabolic process GO:0033240 5 0.129
regulation of macrophage activation GO:0043030 17 0.128
negative regulation of cellular component organization GO:0051129 194 0.128
b cell chemotaxis GO:0035754 3 0.126
positive regulation of lymphocyte proliferation GO:0050671 70 0.125
regulation of cellular response to stress GO:0080135 159 0.125
negative regulation of lymphocyte activation GO:0051250 91 0.125
nucleotide metabolic process GO:0009117 332 0.124
regulation of immunological synapse formation GO:2000520 2 0.124
purine nucleoside catabolic process GO:0006152 205 0.124
glycoprotein biosynthetic process GO:0009101 89 0.124
peptidyl amino acid modification GO:0018193 336 0.124
muscle cell development GO:0055001 133 0.123
positive regulation of secretion by cell GO:1903532 114 0.121
response to fatty acid GO:0070542 8 0.120
calcium ion homeostasis GO:0055074 127 0.120
regulation of leukocyte apoptotic process GO:2000106 56 0.120
purine ribonucleotide metabolic process GO:0009150 290 0.120
cytosolic calcium ion homeostasis GO:0051480 70 0.120
regulation of chemokine biosynthetic process GO:0045073 8 0.119
positive regulation of b cell mediated immunity GO:0002714 26 0.118
regulation of macrophage chemotaxis GO:0010758 8 0.118
response to extracellular stimulus GO:0009991 127 0.118
tumor necrosis factor production GO:0032640 50 0.116
regulation of interleukin 8 production GO:0032677 3 0.116
glycosyl compound catabolic process GO:1901658 206 0.115
positive regulation of t helper 1 type immune response GO:0002827 12 0.115
regulation of b cell chemotaxis GO:2000537 2 0.115
positive regulation of cytokine biosynthetic process GO:0042108 40 0.114
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.114
positive regulation of lymphocyte activation GO:0051251 140 0.113
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.113
defense response to gram negative bacterium GO:0050829 28 0.112
muscle fiber development GO:0048747 76 0.111
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.111
regulation of cell cycle GO:0051726 281 0.111
purine nucleoside metabolic process GO:0042278 241 0.111
striated muscle tissue development GO:0014706 293 0.111
regulation of nucleotide metabolic process GO:0006140 169 0.110
negative regulation of vasculature development GO:1901343 26 0.109
macromolecule catabolic process GO:0009057 281 0.109
cellular homeostasis GO:0019725 240 0.108
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.108
regulation of cytoskeleton organization GO:0051493 122 0.106
regulation of lymphocyte differentiation GO:0045619 107 0.106
regulation of ras protein signal transduction GO:0046578 114 0.106
positive regulation of programmed cell death GO:0043068 218 0.106
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.105
cognition GO:0050890 149 0.104
epithelium migration GO:0090132 63 0.104
nucleobase containing small molecule metabolic process GO:0055086 352 0.104
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.103
interleukin 1 beta secretion GO:0050702 16 0.103
telencephalon development GO:0021537 186 0.103
positive regulation of phospholipase activity GO:0010518 3 0.102
glycosyl compound metabolic process GO:1901657 246 0.102
regulation of lymphocyte mediated immunity GO:0002706 84 0.102
response to radiation GO:0009314 165 0.101
regulation of alpha beta t cell activation GO:0046634 53 0.101
positive regulation of blood coagulation GO:0030194 10 0.100
regulation of t helper 1 cell cytokine production GO:2000554 1 0.100
regulation of protein complex assembly GO:0043254 83 0.100
Human
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.100
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.099
antibacterial peptide production GO:0002778 2 0.099
positive regulation of ras gtpase activity GO:0032320 65 0.099
alpha beta t cell activation involved in immune response GO:0002287 31 0.097
fatty acid metabolic process GO:0006631 121 0.097
regulation of t helper 2 cell cytokine production GO:2000551 3 0.097
hypersensitivity GO:0002524 10 0.097
negative regulation of apoptotic signaling pathway GO:2001234 104 0.096
organic hydroxy compound metabolic process GO:1901615 203 0.096
i kappab kinase nf kappab signaling GO:0007249 85 0.096
regulation of t cell activation GO:0050863 170 0.096
immunoglobulin production in mucosal tissue GO:0002426 3 0.096
developmental growth involved in morphogenesis GO:0060560 138 0.096
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.096
regulation of exocytosis GO:0017157 61 0.095
negative regulation of secretion GO:0051048 61 0.095
positive regulation of hypersensitivity GO:0002885 7 0.095
response to transforming growth factor beta GO:0071559 88 0.095
activation of mapk activity GO:0000187 59 0.094
tissue migration GO:0090130 68 0.094
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.093
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.093
positive regulation of chemokine production GO:0032722 22 0.093
cellular response to oxidative stress GO:0034599 76 0.092
regulation of fat cell differentiation GO:0045598 81 0.092
epithelial cell migration GO:0010631 63 0.092
macrophage activation GO:0042116 27 0.092
protein import into nucleus GO:0006606 95 0.092
regulation of jnk cascade GO:0046328 62 0.092
peptide transport GO:0015833 133 0.091
purine nucleotide metabolic process GO:0006163 302 0.091
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.091
response to interleukin 18 GO:0070673 4 0.090
regulation of leukocyte differentiation GO:1902105 159 0.090
platelet activation GO:0030168 40 0.089
regulation of alpha beta t cell proliferation GO:0046640 18 0.089
dendritic cell migration GO:0036336 12 0.089
neutrophil mediated immunity GO:0002446 19 0.088
cellular divalent inorganic cation homeostasis GO:0072503 127 0.088
oxidation reduction process GO:0055114 342 0.088
purine nucleoside triphosphate catabolic process GO:0009146 203 0.088
cellular response to lipid GO:0071396 145 0.087
cellular ion homeostasis GO:0006873 165 0.087
positive regulation of protein phosphorylation GO:0001934 242 0.087
t cell differentiation involved in immune response GO:0002292 30 0.087
muscle system process GO:0003012 141 0.086
negative regulation of myoblast differentiation GO:0045662 18 0.086
positive regulation of neuron apoptotic process GO:0043525 25 0.085
icosanoid metabolic process GO:0006690 33 0.084
amide transport GO:0042886 138 0.084
regulation of production of molecular mediator of immune response GO:0002700 65 0.084
membrane lipid metabolic process GO:0006643 53 0.084
antigen processing and presentation GO:0019882 47 0.084
positive regulation of muscle cell differentiation GO:0051149 39 0.083
calcium ion transport GO:0006816 159 0.083
detection of fungus GO:0016046 2 0.082
regulation of interleukin 1 beta production GO:0032651 25 0.082
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.082
peptidyl tyrosine phosphorylation GO:0018108 143 0.082
superoxide metabolic process GO:0006801 27 0.082
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.082
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.080
modification of morphology or physiology of other organism GO:0035821 18 0.080
negative regulation of leukocyte degranulation GO:0043301 7 0.080
small gtpase mediated signal transduction GO:0007264 97 0.079
mapk cascade GO:0000165 281 0.079
regulation of purine nucleotide metabolic process GO:1900542 169 0.079

Selp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.372
disease of anatomical entity DOID:7 0 0.372
disease of cellular proliferation DOID:14566 0 0.224
cancer DOID:162 0 0.151
organ system cancer DOID:0050686 0 0.147
blood coagulation disease DOID:1247 0 0.081
inherited blood coagulation disease DOID:2214 0 0.081
hematopoietic system disease DOID:74 0 0.081