Mus musculus

98 known processes

Sepn1

selenoprotein N, 1

(Aliases: AI414492,1110019I12Rik)

Sepn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein hydroxylation GO:0018126 4 0.402
cellular modified amino acid metabolic process GO:0006575 63 0.281
nucleotide metabolic process GO:0009117 332 0.217
nucleoside phosphate metabolic process GO:0006753 338 0.181
extracellular structure organization GO:0043062 148 0.180
ras protein signal transduction GO:0007265 77 0.171
small gtpase mediated signal transduction GO:0007264 97 0.155
oxidation reduction process GO:0055114 342 0.148
cellular amino acid metabolic process GO:0006520 103 0.145
positive regulation of cell death GO:0010942 224 0.127
positive regulation of apoptotic process GO:0043065 217 0.119
membrane organization GO:0061024 245 0.113
glucose catabolic process GO:0006007 3 0.106
carbohydrate metabolic process GO:0005975 230 0.101
positive regulation of programmed cell death GO:0043068 218 0.100
hexose catabolic process GO:0019320 3 0.097
extracellular matrix organization GO:0030198 147 0.094
regulation of cell motility GO:2000145 236 0.091
peptidyl proline hydroxylation GO:0019511 3 0.081
organelle assembly GO:0070925 177 0.079
nucleobase containing small molecule metabolic process GO:0055086 352 0.077
monocarboxylic acid metabolic process GO:0032787 191 0.072
plasma membrane organization GO:0007009 90 0.068
rho protein signal transduction GO:0007266 32 0.066
epithelial tube morphogenesis GO:0060562 303 0.065
intracellular protein transport GO:0006886 204 0.063
striated muscle cell development GO:0055002 125 0.060
response to oxidative stress GO:0006979 123 0.059
ossification GO:0001503 216 0.059
nadph regeneration GO:0006740 2 0.054
glycoprotein metabolic process GO:0009100 116 0.054
g1 s transition of mitotic cell cycle GO:0000082 57 0.051
respiratory system development GO:0060541 190 0.051
energy derivation by oxidation of organic compounds GO:0015980 77 0.050
anatomical structure homeostasis GO:0060249 145 0.050
pentose phosphate shunt GO:0006098 2 0.049
endomembrane system organization GO:0010256 147 0.048
regulation of protein localization GO:0032880 231 0.047
response to inorganic substance GO:0010035 96 0.045
morphogenesis of a branching structure GO:0001763 203 0.045
myeloid leukocyte differentiation GO:0002573 119 0.044
positive regulation of protein export from nucleus GO:0046827 4 0.044
skeletal system development GO:0001501 356 0.043
positive regulation of dendrite development GO:1900006 21 0.043
carbohydrate derivative biosynthetic process GO:1901137 183 0.042
mesenchymal cell differentiation GO:0048762 107 0.042
aromatic compound catabolic process GO:0019439 286 0.041
muscle cell differentiation GO:0042692 261 0.041
hexose metabolic process GO:0019318 98 0.041
cellular response to dna damage stimulus GO:0006974 207 0.040
positive regulation of protein modification process GO:0031401 299 0.039
mitotic cell cycle process GO:1903047 159 0.039
positive regulation of apoptotic signaling pathway GO:2001235 95 0.039
regulation of establishment of protein localization GO:0070201 181 0.038
posttranscriptional regulation of gene expression GO:0010608 155 0.038
regulation of purine nucleotide metabolic process GO:1900542 169 0.038
carbohydrate catabolic process GO:0016052 32 0.038
sulfur compound metabolic process GO:0006790 100 0.038
regulation of protein serine threonine kinase activity GO:0071900 157 0.037
peptidyl amino acid modification GO:0018193 336 0.037
synapse organization GO:0050808 125 0.037
establishment of vesicle localization GO:0051650 81 0.037
cation transport GO:0006812 399 0.036
cytoplasmic transport GO:0016482 234 0.036
muscle fiber development GO:0048747 76 0.036
coenzyme metabolic process GO:0006732 52 0.036
ensheathment of neurons GO:0007272 76 0.036
male gamete generation GO:0048232 285 0.036
generation of precursor metabolites and energy GO:0006091 103 0.035
meiotic cell cycle GO:0051321 122 0.035
regulation of neuron differentiation GO:0045664 281 0.035
response to organic cyclic compound GO:0014070 198 0.035
peptidyl proline modification GO:0018208 6 0.034
embryonic organ morphogenesis GO:0048562 276 0.034
mesenchymal cell development GO:0014031 93 0.034
response to organonitrogen compound GO:0010243 246 0.034
regulation of membrane potential GO:0042391 192 0.034
digestive system development GO:0055123 200 0.034
regulation of system process GO:0044057 200 0.033
collagen fibril organization GO:0030199 32 0.033
appendage morphogenesis GO:0035107 149 0.033
multicellular organismal homeostasis GO:0048871 164 0.033
basement membrane assembly GO:0070831 2 0.033
glycoprotein biosynthetic process GO:0009101 89 0.032
regulation of ras protein signal transduction GO:0046578 114 0.032
ribonucleoside metabolic process GO:0009119 245 0.032
apoptotic signaling pathway GO:0097190 306 0.031
multicellular organismal signaling GO:0035637 91 0.031
cellular response to organonitrogen compound GO:0071417 145 0.031
regulation of cell migration GO:0030334 219 0.031
stem cell differentiation GO:0048863 268 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.031
cellular response to lipid GO:0071396 145 0.030
regulation of ossification GO:0030278 112 0.030
bone development GO:0060348 120 0.030
regulation of cellular catabolic process GO:0031329 242 0.029
muscle cell development GO:0055001 133 0.029
regulation of organelle organization GO:0033043 289 0.029
regulation of protein transport GO:0051223 163 0.029
positive regulation of cell development GO:0010720 237 0.029
chemotaxis GO:0006935 247 0.028
nicotinamide nucleotide metabolic process GO:0046496 12 0.028
action potential GO:0001508 78 0.028
vesicle localization GO:0051648 86 0.028
cellular response to oxidative stress GO:0034599 76 0.028
cellular response to abiotic stimulus GO:0071214 56 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
mitotic cell cycle GO:0000278 195 0.028
tissue homeostasis GO:0001894 115 0.028
blood circulation GO:0008015 195 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
cofactor metabolic process GO:0051186 80 0.027
cellular response to organic cyclic compound GO:0071407 87 0.027
kidney development GO:0001822 213 0.027
wnt signaling pathway GO:0016055 188 0.027
nadp metabolic process GO:0006739 6 0.027
protein localization to membrane GO:0072657 108 0.026
organophosphate biosynthetic process GO:0090407 122 0.026
regulation of neuron death GO:1901214 134 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
regulation of hormone levels GO:0010817 211 0.026
protein targeting GO:0006605 143 0.025
positive regulation of protein kinase activity GO:0045860 144 0.025
macromolecule glycosylation GO:0043413 55 0.025
neuronal action potential GO:0019228 54 0.025
myelination GO:0042552 74 0.025
cellular response to hormone stimulus GO:0032870 150 0.025
transmission of nerve impulse GO:0019226 76 0.025
regulation of transferase activity GO:0051338 263 0.025
cartilage development GO:0051216 140 0.025
oxidoreduction coenzyme metabolic process GO:0006733 16 0.024
neural tube development GO:0021915 160 0.024
regulation of vacuole organization GO:0044088 4 0.024
ear development GO:0043583 200 0.024
cellular component assembly involved in morphogenesis GO:0010927 139 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
cell type specific apoptotic process GO:0097285 268 0.024
negative regulation of dna replication GO:0008156 4 0.023
glucose metabolic process GO:0006006 92 0.023
protein maturation GO:0051604 176 0.023
positive regulation of muscle cell differentiation GO:0051149 39 0.023
establishment of synaptic vesicle localization GO:0097480 57 0.023
regulation of secretion GO:0051046 274 0.023
ameboidal type cell migration GO:0001667 128 0.023
regulation of neuron apoptotic process GO:0043523 122 0.022
negative regulation of ras protein signal transduction GO:0046580 18 0.022
production of molecular mediator of immune response GO:0002440 103 0.022
response to lipopolysaccharide GO:0032496 128 0.022
muscle tissue development GO:0060537 308 0.022
epidermis development GO:0008544 187 0.022
cell adhesion GO:0007155 329 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
neural precursor cell proliferation GO:0061351 121 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
protein glycosylation GO:0006486 55 0.021
regulation of vesicle mediated transport GO:0060627 139 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
cell cycle g1 s phase transition GO:0044843 57 0.021
response to superoxide GO:0000303 16 0.021
establishment of protein localization to membrane GO:0090150 54 0.021
cellular homeostasis GO:0019725 240 0.021
amine metabolic process GO:0009308 45 0.021
regulation of protein stability GO:0031647 52 0.021
chondrocyte differentiation GO:0002062 72 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.020
regulation of cell cycle process GO:0010564 160 0.020
positive regulation of cell motility GO:2000147 116 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
nucleoside metabolic process GO:0009116 246 0.020
vasodilation GO:0042311 28 0.020
mesenchyme development GO:0060485 152 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
spermatogenesis GO:0007283 284 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
response to osmotic stress GO:0006970 21 0.019
positive regulation of intracellular transport GO:0032388 70 0.019
epithelial to mesenchymal transition GO:0001837 47 0.019
purine containing compound metabolic process GO:0072521 311 0.019
protein processing GO:0016485 163 0.019
nuclear division GO:0000280 158 0.019
superoxide metabolic process GO:0006801 27 0.019
cation transmembrane transport GO:0098655 266 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.019
regulation of cellular response to stress GO:0080135 159 0.019
skin development GO:0043588 220 0.019
regulation of hydrolase activity GO:0051336 246 0.019
blood vessel morphogenesis GO:0048514 285 0.019
regulation of tube size GO:0035150 57 0.019
negative regulation of cell cycle GO:0045786 123 0.019
neurotransmitter secretion GO:0007269 62 0.018
skeletal system morphogenesis GO:0048705 203 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
ear morphogenesis GO:0042471 118 0.018
regulation of protein binding GO:0043393 60 0.018
cardiac chamber development GO:0003205 108 0.018
regulation of protein catabolic process GO:0042176 108 0.018
regulation of myotube differentiation GO:0010830 62 0.018
response to acid chemical GO:0001101 111 0.018
macromolecule catabolic process GO:0009057 281 0.018
response to nutrient levels GO:0031667 109 0.018
rhythmic process GO:0048511 174 0.018
positive regulation of secretion GO:0051047 130 0.017
sensory organ morphogenesis GO:0090596 242 0.017
response to radiation GO:0009314 165 0.017
cellular amide metabolic process GO:0043603 58 0.017
circulatory system process GO:0003013 197 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
response to oxygen levels GO:0070482 62 0.017
glycerophospholipid metabolic process GO:0006650 71 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
cellular amine metabolic process GO:0044106 44 0.017
calcium ion transport GO:0006816 159 0.017
regulation of muscle tissue development GO:1901861 97 0.017
alpha amino acid metabolic process GO:1901605 59 0.017
axonogenesis GO:0007409 274 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
cellular response to salt stress GO:0071472 1 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
ion transmembrane transport GO:0034220 361 0.017
positive regulation of gene silencing by mirna GO:2000637 1 0.017
glycosylation GO:0070085 62 0.017
regulation of proteolysis GO:0030162 164 0.017
positive regulation of protein transport GO:0051222 93 0.016
glycerolipid metabolic process GO:0046486 122 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
rac protein signal transduction GO:0016601 13 0.016
glial cell differentiation GO:0010001 131 0.016
pyridine nucleotide metabolic process GO:0019362 12 0.016
synaptic vesicle localization GO:0097479 59 0.016
gtp metabolic process GO:0046039 144 0.016
locomotory behavior GO:0007626 195 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
stem cell development GO:0048864 219 0.016
regulation of binding GO:0051098 111 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
gastrulation GO:0007369 116 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
sulfur compound biosynthetic process GO:0044272 37 0.016
endocytosis GO:0006897 168 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
cardiac ventricle development GO:0003231 83 0.015
regulation of organ morphogenesis GO:2000027 144 0.015
cellular response to acid chemical GO:0071229 68 0.015
protein localization to plasma membrane GO:0072659 57 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
regulation of map kinase activity GO:0043405 120 0.015
exocytosis GO:0006887 121 0.015
glucose transport GO:0015758 56 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
positive regulation of proteolysis GO:0045862 85 0.015
regulation of gtp catabolic process GO:0033124 113 0.015
schwann cell differentiation GO:0014037 26 0.015
vascular process in circulatory system GO:0003018 62 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
ribonucleotide catabolic process GO:0009261 208 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.014
branching morphogenesis of an epithelial tube GO:0048754 159 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
regulation of intracellular protein transport GO:0033157 82 0.014
mucopolysaccharide metabolic process GO:1903510 25 0.014
lipid biosynthetic process GO:0008610 179 0.014
regulation of protein kinase activity GO:0045859 232 0.014
organophosphate catabolic process GO:0046434 232 0.014
regulation of cell cycle GO:0051726 281 0.014
pyridine containing compound metabolic process GO:0072524 14 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.014
positive regulation of transferase activity GO:0051347 167 0.014
renal system development GO:0072001 225 0.014
monosaccharide metabolic process GO:0005996 106 0.014
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.014
regulation of cellular amine metabolic process GO:0033238 20 0.014
negative regulation of protein modification process GO:0031400 163 0.014
positive regulation of fatty acid oxidation GO:0046321 4 0.013
lipid localization GO:0010876 126 0.013
body morphogenesis GO:0010171 45 0.013
embryonic skeletal system morphogenesis GO:0048704 91 0.013
digestive tract morphogenesis GO:0048546 147 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
cellular ketone metabolic process GO:0042180 84 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
single organism nuclear import GO:1902593 95 0.013
positive regulation of innate immune response GO:0045089 80 0.013
negative regulation of neuron death GO:1901215 98 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
synaptic vesicle transport GO:0048489 57 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
response to extracellular stimulus GO:0009991 127 0.013
cerebellar granule cell precursor tangential migration GO:0021935 1 0.013
cellular chemical homeostasis GO:0055082 215 0.013
regulation of synaptic vesicle transport GO:1902803 13 0.013
peptide metabolic process GO:0006518 46 0.013
digestive tract development GO:0048565 190 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
organelle fission GO:0048285 170 0.013
nucleotide catabolic process GO:0009166 217 0.013
cell growth GO:0016049 130 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
striated muscle tissue development GO:0014706 293 0.013
protein catabolic process GO:0030163 221 0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.012
response to growth factor GO:0070848 198 0.012
regulation of vasculature development GO:1901342 88 0.012
skeletal muscle organ development GO:0060538 163 0.012
positive regulation of kinase activity GO:0033674 155 0.012
gtp catabolic process GO:0006184 143 0.012
response to light stimulus GO:0009416 135 0.012
protein secretion GO:0009306 111 0.012
axon ensheathment GO:0008366 76 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
positive regulation of defense response GO:0031349 124 0.012
regulation of innate immune response GO:0045088 91 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
regulation of nucleocytoplasmic transport GO:0046822 73 0.012
sensory perception GO:0007600 245 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
mitochondrion distribution GO:0048311 4 0.012
synaptic transmission GO:0007268 329 0.012
lipid transport GO:0006869 98 0.012
regulation of endocytosis GO:0030100 69 0.012
connective tissue development GO:0061448 179 0.012
heart morphogenesis GO:0003007 178 0.012
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.012
regulation of osteoclast differentiation GO:0045670 36 0.012
embryonic skeletal system development GO:0048706 120 0.012
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.012
divalent inorganic cation transport GO:0072511 178 0.012
cell division GO:0051301 120 0.012
establishment of glial blood brain barrier GO:0060857 2 0.012
gene silencing GO:0016458 38 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
removal of superoxide radicals GO:0019430 12 0.012
nuclear transport GO:0051169 139 0.012
mapk cascade GO:0000165 281 0.012
regulation of ral gtpase activity GO:0032315 4 0.012
phosphatidylserine exposure on apoptotic cell surface GO:0070782 2 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
anion transport GO:0006820 177 0.012
regulation of leukocyte differentiation GO:1902105 159 0.011
blastocyst development GO:0001824 80 0.011
negative regulation of nervous system development GO:0051961 156 0.011
negative regulation of molecular function GO:0044092 258 0.011
gland development GO:0048732 330 0.011
osteoclast differentiation GO:0030316 62 0.011
skin morphogenesis GO:0043589 38 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
regulation of blood vessel size GO:0050880 56 0.011
dephosphorylation GO:0016311 129 0.011
multicellular organismal aging GO:0010259 24 0.011
ribose phosphate biosynthetic process GO:0046390 59 0.011
glycosaminoglycan metabolic process GO:0030203 34 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
inner ear morphogenesis GO:0042472 101 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
establishment of protein localization to plasma membrane GO:0090002 34 0.011
positive regulation of cell migration GO:0030335 109 0.011
multi multicellular organism process GO:0044706 109 0.011
schwann cell development GO:0014044 22 0.011
trabecula morphogenesis GO:0061383 40 0.011
peptide secretion GO:0002790 114 0.011
chromatin organization GO:0006325 206 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.011
asymmetric neuroblast division GO:0055059 1 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
regulation of generation of precursor metabolites and energy GO:0043467 38 0.011
protein stabilization GO:0050821 25 0.011
gene silencing by mirna GO:0035195 10 0.011
response to amino acid GO:0043200 37 0.011
skeletal muscle fiber development GO:0048741 58 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
organic hydroxy compound transport GO:0015850 93 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
regulation of secretion by cell GO:1903530 249 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
fat cell differentiation GO:0045444 160 0.011
cell fate commitment GO:0045165 210 0.011
smoothened signaling pathway GO:0007224 105 0.011
regulation of muscle adaptation GO:0043502 31 0.011
cytokine production GO:0001816 319 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
regionalization GO:0003002 337 0.011
organic acid biosynthetic process GO:0016053 86 0.010
regulation of protein targeting GO:1903533 61 0.010
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.010
tube formation GO:0035148 140 0.010
regulation of defense response GO:0031347 233 0.010
regulation of autophagy GO:0010506 30 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
organic cyclic compound catabolic process GO:1901361 295 0.010
cellular response to inorganic substance GO:0071241 37 0.010
epithelial cell morphogenesis GO:0003382 41 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
myeloid cell differentiation GO:0030099 233 0.010
establishment of organelle localization GO:0051656 122 0.010
cellular response to estrogen stimulus GO:0071391 12 0.010
cyclic nucleotide metabolic process GO:0009187 59 0.010
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.010
regulation of synaptic vesicle exocytosis GO:2000300 11 0.010
epithelial cell development GO:0002064 159 0.010
positive regulation of neuron differentiation GO:0045666 141 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.010

Sepn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.301
disease of anatomical entity DOID:7 0 0.301
connective tissue disease DOID:65 0 0.251
bone disease DOID:0080001 0 0.064
osteochondrodysplasia DOID:2256 0 0.064
bone development disease DOID:0080006 0 0.064
osteogenesis imperfecta DOID:12347 0 0.024
physical disorder DOID:0080015 0 0.024
congenital nervous system abnormality DOID:2490 0 0.017
muscle tissue disease DOID:66 0 0.017
muscular disease DOID:0080000 0 0.017