Mus musculus

12 known processes

Serpina3k

serine (or cysteine) peptidase inhibitor, clade A, member 3K

(Aliases: Spi2,contrapsin,1300001I07Rik,RP54,Spi-2,MMSpi2,D12Rp54,MMCM2)

Serpina3k biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sterol metabolic process GO:0016125 58 0.892
Mouse
regulation of cholesterol metabolic process GO:0090181 14 0.765
Mouse
acylglycerol metabolic process GO:0006639 55 0.675
Mouse
cholesterol metabolic process GO:0008203 56 0.600
Mouse
steroid metabolic process GO:0008202 119 0.599
Mouse
negative regulation of gluconeogenesis GO:0045721 9 0.547
Mouse
macromolecule glycosylation GO:0043413 55 0.538
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.530
Mouse
triglyceride metabolic process GO:0006641 51 0.493
Mouse
hexose biosynthetic process GO:0019319 39 0.466
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.452
Mouse
cellular ketone metabolic process GO:0042180 84 0.448
Mouse
lipid biosynthetic process GO:0008610 179 0.431
Mouse
fatty acid metabolic process GO:0006631 121 0.412
Mouse
cellular lipid metabolic process GO:0044255 323 0.393
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.289
Mouse
regulation of lipid metabolic process GO:0019216 118 0.279
Mouse
alcohol metabolic process GO:0006066 116 0.269
Mouse
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.266
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.264
Mouse
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.260
Mouse
hexose metabolic process GO:0019318 98 0.250
Mouse
glucose metabolic process GO:0006006 92 0.236
Mouse
neutral lipid metabolic process GO:0006638 57 0.232
Mouse
activation of membrane attack complex GO:0001905 4 0.231
oxidation reduction process GO:0055114 342 0.227
regulation of glucose metabolic process GO:0010906 60 0.220
Mouse
response to organonitrogen compound GO:0010243 246 0.216
positive regulation of lipid metabolic process GO:0045834 40 0.215
Mouse
amine metabolic process GO:0009308 45 0.201
negative regulation of carbohydrate metabolic process GO:0045912 19 0.201
Mouse
inflammatory response GO:0006954 244 0.191
Mouse
regulation of protein maturation GO:1903317 96 0.191
Mouse
regulation of insulin receptor signaling pathway GO:0046626 21 0.188
Mouse
glycosylation GO:0070085 62 0.173
Mouse
negative regulation of hydrolase activity GO:0051346 71 0.168
Mouse
regulation of protein processing GO:0070613 96 0.157
Mouse
regulation of hormone levels GO:0010817 211 0.150
Mouse
regulation of carbohydrate biosynthetic process GO:0043255 40 0.150
Mouse
protein processing GO:0016485 163 0.149
Mouse
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.144
Mouse
regulation of gluconeogenesis GO:0006111 30 0.143
Mouse
negative regulation of molecular function GO:0044092 258 0.140
Mouse
glycerolipid metabolic process GO:0046486 122 0.137
Mouse
monocarboxylic acid biosynthetic process GO:0072330 61 0.134
Mouse
negative regulation of endopeptidase activity GO:0010951 44 0.131
Mouse
regulation of complement activation GO:0030449 7 0.129
regulation of cellular amine metabolic process GO:0033238 20 0.125
regulation of secretion GO:0051046 274 0.123
Mouse
protein activation cascade GO:0072376 19 0.120
negative regulation of protein processing GO:0010955 79 0.117
Mouse
carbohydrate biosynthetic process GO:0016051 74 0.116
Mouse
carbohydrate metabolic process GO:0005975 230 0.115
Mouse
negative regulation of peptidase activity GO:0010466 46 0.113
Mouse
response to organic cyclic compound GO:0014070 198 0.111
lipid transport GO:0006869 98 0.108
nitrogen compound transport GO:0071705 271 0.108
regulation of defense response GO:0031347 233 0.107
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.106
Mouse
regulation of triglyceride metabolic process GO:0090207 17 0.105
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.105
cellular amino acid metabolic process GO:0006520 103 0.103
regulation of carbohydrate metabolic process GO:0006109 75 0.099
Mouse
negative regulation of protein maturation GO:1903318 79 0.097
Mouse
complement activation GO:0006956 16 0.097
glucocorticoid metabolic process GO:0008211 9 0.096
Mouse
angiogenesis GO:0001525 201 0.095
Rat
regulation of steroid metabolic process GO:0019218 39 0.094
Mouse
regulation of hydrolase activity GO:0051336 246 0.090
Mouse
regulation of response to wounding GO:1903034 189 0.090
Mouse
response to peptide hormone GO:0043434 127 0.088
glycoprotein metabolic process GO:0009100 116 0.087
Mouse
regulation of feeding behavior GO:0060259 3 0.086
regulation of protein kinase c activity GO:1900019 1 0.084
Mouse
renal system development GO:0072001 225 0.082
Mouse
organic acid biosynthetic process GO:0016053 86 0.082
Mouse
immune effector process GO:0002252 321 0.081
cellular carbohydrate metabolic process GO:0044262 119 0.077
Mouse
negative regulation of proteolysis GO:0045861 74 0.077
Mouse
cellular lipid catabolic process GO:0044242 52 0.075
gland development GO:0048732 330 0.075
protein maturation GO:0051604 176 0.073
Mouse
activation of immune response GO:0002253 138 0.072
response to stilbenoid GO:0035634 22 0.071
regulation of proteolysis GO:0030162 164 0.070
Mouse
monosaccharide metabolic process GO:0005996 106 0.070
Mouse
negative regulation of cell proliferation GO:0008285 296 0.068
Mouse Rat
organonitrogen compound catabolic process GO:1901565 264 0.066
positive regulation of activation of membrane attack complex GO:0001970 2 0.066
peptidyl amino acid modification GO:0018193 336 0.066
Mouse
regulation of body fluid levels GO:0050878 162 0.065
regulation of fatty acid metabolic process GO:0019217 28 0.064
Mouse
protein glycosylation GO:0006486 55 0.063
Mouse
positive regulation of protein kinase c activity GO:1900020 1 0.063
Mouse
regulation of endopeptidase activity GO:0052548 89 0.063
Mouse
gluconeogenesis GO:0006094 39 0.059
Mouse
regulation of lipid biosynthetic process GO:0046890 54 0.058
Mouse
glycoprotein biosynthetic process GO:0009101 89 0.058
Mouse
response to peptide GO:1901652 136 0.057
morphogenesis of a branching epithelium GO:0061138 193 0.057
Mouse
organic hydroxy compound transport GO:0015850 93 0.056
rhythmic process GO:0048511 174 0.056
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.055
Mouse
cellular response to hormone stimulus GO:0032870 150 0.055
Mouse
camera type eye development GO:0043010 266 0.053
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.053
Mouse
regulation of renal output by angiotensin GO:0002019 2 0.052
Mouse
muscle cell differentiation GO:0042692 261 0.051
Mouse
protein oligomerization GO:0051259 67 0.051
positive regulation of protein activation cascade GO:2000259 2 0.050
regulation of blood vessel size GO:0050880 56 0.050
Mouse
insulin receptor signaling pathway GO:0008286 49 0.049
Mouse
carboxylic acid biosynthetic process GO:0046394 86 0.049
Mouse
lipid catabolic process GO:0016042 69 0.048
organic cyclic compound catabolic process GO:1901361 295 0.046
monosaccharide biosynthetic process GO:0046364 44 0.046
Mouse
cellular chemical homeostasis GO:0055082 215 0.046
sensory perception GO:0007600 245 0.045
male gamete generation GO:0048232 285 0.045
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.045
fat cell differentiation GO:0045444 160 0.045
positive regulation of apoptotic process GO:0043065 217 0.045
Rat
progesterone metabolic process GO:0042448 4 0.044
regulation of kinase activity GO:0043549 249 0.044
Mouse
cholesterol homeostasis GO:0042632 44 0.044
protein n linked glycosylation GO:0006487 12 0.043
Mouse
kidney epithelium development GO:0072073 121 0.043
Mouse
renal tubular secretion GO:0097254 2 0.043
reactive nitrogen species metabolic process GO:2001057 0 0.043
cellular response to peptide hormone stimulus GO:0071375 92 0.043
Mouse
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.043
Mouse
cellular response to insulin stimulus GO:0032869 78 0.042
Mouse
lipid homeostasis GO:0055088 63 0.042
cellular response to organonitrogen compound GO:0071417 145 0.042
Mouse
response to inorganic substance GO:0010035 96 0.041
small molecule biosynthetic process GO:0044283 132 0.041
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.040
generation of precursor metabolites and energy GO:0006091 103 0.040
small molecule catabolic process GO:0044282 71 0.040
regulation of blood vessel size by renin angiotensin GO:0002034 5 0.040
Mouse
regulation of peptidase activity GO:0052547 96 0.039
Mouse
regulation of mapk cascade GO:0043408 248 0.039
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.039
negative regulation of lipid metabolic process GO:0045833 30 0.038
Mouse
organic acid catabolic process GO:0016054 51 0.038
regulation of system process GO:0044057 200 0.038
positive regulation of cell death GO:0010942 224 0.038
Rat
nucleoside triphosphate metabolic process GO:0009141 230 0.037
regulation of transferase activity GO:0051338 263 0.037
Mouse
blood vessel morphogenesis GO:0048514 285 0.037
Rat
cellular amine metabolic process GO:0044106 44 0.037
regulation of protein activation cascade GO:2000257 7 0.036
mapk cascade GO:0000165 281 0.036
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.036
phagocytosis GO:0006909 66 0.036
spermatogenesis GO:0007283 284 0.036
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.036
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.035
Mouse
macromolecule catabolic process GO:0009057 281 0.035
smoothened signaling pathway GO:0007224 105 0.034
gliogenesis GO:0042063 141 0.034
Mouse
protein homooligomerization GO:0051260 43 0.034
response to steroid hormone GO:0048545 56 0.034
fibrinolysis GO:0042730 3 0.034
regulation of cell activation GO:0050865 289 0.034
hormone metabolic process GO:0042445 86 0.033
Mouse
retinoid metabolic process GO:0001523 24 0.033
lymphocyte mediated immunity GO:0002449 139 0.033
positive regulation of mapk cascade GO:0043410 170 0.033
Mouse
terpenoid metabolic process GO:0006721 25 0.032
cellular response to lipid GO:0071396 145 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.032
locomotory behavior GO:0007626 195 0.032
innate immune response GO:0045087 157 0.032
leukocyte mediated immunity GO:0002443 174 0.032
purine containing compound metabolic process GO:0072521 311 0.032
adaptive immune response GO:0002250 155 0.032
hormone secretion GO:0046879 128 0.031
positive regulation of kinase activity GO:0033674 155 0.031
Mouse
regulation of secretion by cell GO:1903530 249 0.031
Mouse
forebrain development GO:0030900 302 0.031
hemostasis GO:0007599 78 0.031
response to phenylpropanoid GO:0080184 22 0.031
cation transport GO:0006812 399 0.031
translation GO:0006412 93 0.031
glucose homeostasis GO:0042593 128 0.031
glycosyl compound catabolic process GO:1901658 206 0.031
regulation of multi organism process GO:0043900 111 0.031
fatty acid biosynthetic process GO:0006633 41 0.030
Mouse
cell type specific apoptotic process GO:0097285 268 0.030
Mouse
vascular process in circulatory system GO:0003018 62 0.030
Mouse
epidermis development GO:0008544 187 0.030
cytokine production GO:0001816 319 0.030
Mouse
humoral immune response GO:0006959 57 0.029
anion transport GO:0006820 177 0.029
aromatic compound catabolic process GO:0019439 286 0.029
regulation of lipoprotein lipase activity GO:0051004 4 0.029
response to acid chemical GO:0001101 111 0.029
cellular response to food GO:0071240 1 0.029
lipid localization GO:0010876 126 0.029
renal system process GO:0003014 48 0.028
Mouse
ovarian follicle rupture GO:0001543 2 0.028
Mouse
epithelial tube morphogenesis GO:0060562 303 0.028
Mouse
regulation of neurotransmitter levels GO:0001505 87 0.028
nucleotide metabolic process GO:0009117 332 0.028
regulation of fat cell differentiation GO:0045598 81 0.027
regulation of inflammatory response GO:0050727 147 0.027
Mouse
regulation of cellular response to insulin stimulus GO:1900076 30 0.027
Mouse
positive regulation of protein modification process GO:0031401 299 0.027
Mouse
energy derivation by oxidation of organic compounds GO:0015980 77 0.027
leukocyte activation involved in immune response GO:0002366 126 0.027
response to extracellular stimulus GO:0009991 127 0.027
cellular response to peptide GO:1901653 92 0.026
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.025
endocytosis GO:0006897 168 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
divalent inorganic cation homeostasis GO:0072507 138 0.025
negative regulation of multi organism process GO:0043901 68 0.025
positive regulation of transferase activity GO:0051347 167 0.025
Mouse
acute inflammatory response GO:0002526 41 0.025
cell matrix adhesion GO:0007160 68 0.025
Mouse
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.025
Mouse
positive regulation of fatty acid oxidation GO:0046321 4 0.025
regulation of establishment of protein localization GO:0070201 181 0.024
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.024
amide transport GO:0042886 138 0.024
transmembrane transport GO:0055085 412 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
cellular homeostasis GO:0019725 240 0.023
liver development GO:0001889 66 0.023
organic anion transport GO:0015711 137 0.023
cytokine mediated signaling pathway GO:0019221 115 0.023
muscle system process GO:0003012 141 0.023
Mouse
carbohydrate homeostasis GO:0033500 128 0.023
ribonucleotide catabolic process GO:0009261 208 0.023
regulation of protein serine threonine kinase activity GO:0071900 157 0.022
Mouse
organelle localization GO:0051640 179 0.022
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.022
branching morphogenesis of an epithelial tube GO:0048754 159 0.022
Mouse
regulation of cell adhesion GO:0030155 154 0.022
energy reserve metabolic process GO:0006112 39 0.022
negative regulation of epithelial cell proliferation GO:0050680 64 0.022
Rat
purine nucleoside metabolic process GO:0042278 241 0.022
isoprenoid metabolic process GO:0006720 29 0.022
sterol homeostasis GO:0055092 45 0.022
sensory organ morphogenesis GO:0090596 242 0.022
sensory perception of mechanical stimulus GO:0050954 107 0.022
cell adhesion GO:0007155 329 0.022
Mouse
peptide secretion GO:0002790 114 0.022
cellular divalent inorganic cation homeostasis GO:0072503 127 0.022
acetylcholine catabolic process GO:0006581 1 0.022
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.022
Mouse
response to oxidative stress GO:0006979 123 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
establishment of blood nerve barrier GO:0008065 3 0.021
Mouse
response to drug GO:0042493 75 0.021
negative regulation of complement activation GO:0045916 3 0.021
regulation of protein kinase activity GO:0045859 232 0.021
Mouse
interspecies interaction between organisms GO:0044419 83 0.021
blood circulation GO:0008015 195 0.021
Mouse
regulation of vasculature development GO:1901342 88 0.021
Rat
fertilization GO:0009566 127 0.021
cofactor metabolic process GO:0051186 80 0.021
response to nutrient levels GO:0031667 109 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.021
regulation of anatomical structure size GO:0090066 178 0.021
Mouse
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 15 0.020
Mouse
circulatory system process GO:0003013 197 0.020
Mouse
nucleoside monophosphate metabolic process GO:0009123 85 0.020
chemotaxis GO:0006935 247 0.020
cellular response to cadmium ion GO:0071276 3 0.020
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.020
smad protein signal transduction GO:0060395 21 0.020
regulation of cell cycle GO:0051726 281 0.020
peptide transport GO:0015833 133 0.020
positive regulation of plasminogen activation GO:0010756 2 0.020
regulation of protein transport GO:0051223 163 0.020
Mouse
positive regulation of steroid hormone secretion GO:2000833 2 0.020
lipid storage GO:0019915 36 0.020
regulation of translation GO:0006417 71 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
ion transmembrane transport GO:0034220 361 0.019
response to monosaccharide GO:0034284 67 0.019
regulation of adaptive immune response GO:0002819 90 0.019
porphyrin containing compound metabolic process GO:0006778 22 0.019
protein catabolic process GO:0030163 221 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
skin development GO:0043588 220 0.018
negative regulation of protein activation cascade GO:2000258 3 0.018
lymphocyte differentiation GO:0030098 242 0.018
negative regulation of serine type endopeptidase activity GO:1900004 2 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
regulation of plasminogen activation GO:0010755 4 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
positive regulation of protein maturation GO:1903319 7 0.018
nucleotide catabolic process GO:0009166 217 0.018
positive regulation of complement activation GO:0045917 2 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.018
protein secretion GO:0009306 111 0.018
Mouse
heme metabolic process GO:0042168 16 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
coagulation GO:0050817 78 0.017
regulation of leukocyte mediated immunity GO:0002703 104 0.017
regulation of tube size GO:0035150 57 0.017
Mouse
peptide hormone secretion GO:0030072 109 0.017
regulation of intracellular transport GO:0032386 159 0.017
regulation of blood pressure GO:0008217 93 0.017
Mouse
positive regulation of secretion GO:0051047 130 0.017
Mouse
muscle contraction GO:0006936 101 0.017
Mouse
medium chain fatty acid metabolic process GO:0051791 1 0.017
regulation of fatty acid oxidation GO:0046320 10 0.017
organ growth GO:0035265 117 0.017
Mouse
cellular ion homeostasis GO:0006873 165 0.017
regulation of blood coagulation GO:0030193 28 0.017
hepaticobiliary system development GO:0061008 67 0.017
inositol lipid mediated signaling GO:0048017 41 0.017
Mouse
alpha amino acid metabolic process GO:1901605 59 0.017
defense response to other organism GO:0098542 197 0.017
blood coagulation GO:0007596 76 0.017
response to radiation GO:0009314 165 0.017
purine nucleotide metabolic process GO:0006163 302 0.016
heterocycle catabolic process GO:0046700 280 0.016
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 4 0.016
regulation of lymphocyte mediated immunity GO:0002706 84 0.016
female sex differentiation GO:0046660 84 0.016
Mouse
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.016
Mouse
glial cell differentiation GO:0010001 131 0.016
Mouse
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.016
renin angiotensin regulation of aldosterone production GO:0002018 3 0.016
Mouse
t cell activation GO:0042110 289 0.016
lipoprotein metabolic process GO:0042157 43 0.016
fatty acid catabolic process GO:0009062 25 0.016
regulation of cell growth GO:0001558 91 0.016
epithelial cell proliferation GO:0050673 174 0.016
Rat
maintenance of location GO:0051235 89 0.016
regulation of neuron projection development GO:0010975 169 0.016
positive regulation of growth GO:0045927 104 0.016
Mouse
neuron death GO:0070997 154 0.016
Mouse
short chain fatty acid catabolic process GO:0019626 2 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
activation of nf kappab inducing kinase activity GO:0007250 4 0.016
Mouse
carboxylic acid catabolic process GO:0046395 51 0.016
cation homeostasis GO:0055080 212 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
Mouse
negative regulation of response to wounding GO:1903035 77 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
Mouse
sterol transport GO:0015918 38 0.015
response to insulin GO:0032868 100 0.015
Mouse
regulation of immunoglobulin mediated immune response GO:0002889 37 0.015
purine containing compound catabolic process GO:0072523 213 0.015
positive regulation of angiogenesis GO:0045766 46 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
protein lipid complex subunit organization GO:0071825 12 0.015
nucleoside metabolic process GO:0009116 246 0.015
epithelial cell development GO:0002064 159 0.015
Mouse
negative regulation of endothelial cell proliferation GO:0001937 8 0.015
Rat
immunoglobulin mediated immune response GO:0016064 69 0.015
regulation of hormone secretion GO:0046883 88 0.015
interaction with symbiont GO:0051702 14 0.015
establishment of organelle localization GO:0051656 122 0.015
regulation of t cell activation GO:0050863 170 0.015
insulin secretion GO:0030073 89 0.015
endocrine hormone secretion GO:0060986 15 0.015
regulation of cytokine secretion GO:0050707 61 0.015
Mouse
negative regulation of cellular component organization GO:0051129 194 0.015
regulation of systemic arterial blood pressure GO:0003073 61 0.014
Mouse
nephron development GO:0072006 109 0.014
Mouse
ear development GO:0043583 200 0.014
regulation of serine type endopeptidase activity GO:1900003 2 0.014
retinal blood vessel morphogenesis GO:0061304 3 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
fatty acid oxidation GO:0019395 28 0.014
regulation of map kinase activity GO:0043405 120 0.014
wound healing GO:0042060 157 0.014
apoptotic signaling pathway GO:0097190 306 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
regulation of wound healing GO:0061041 40 0.014
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.014
Mouse
female gonad development GO:0008585 71 0.014
Mouse
purine nucleotide catabolic process GO:0006195 211 0.014
cell activation involved in immune response GO:0002263 126 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.014
cellular response to acid chemical GO:0071229 68 0.014
metal ion homeostasis GO:0055065 189 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
Mouse
limb development GO:0060173 166 0.013
response to testosterone GO:0033574 3 0.013
cellular response to extracellular stimulus GO:0031668 81 0.013
cell cell junction organization GO:0045216 72 0.013
organ regeneration GO:0031100 2 0.013
regulation of binding GO:0051098 111 0.013
protein localization to organelle GO:0033365 185 0.013
lateral line system development GO:0048925 1 0.013
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.013
Mouse
intracellular protein transport GO:0006886 204 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
negative regulation of fibrinolysis GO:0051918 1 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
lipid modification GO:0030258 65 0.013
regulation of glycogen catabolic process GO:0005981 2 0.013
regulation of plasma lipoprotein particle levels GO:0097006 23 0.013
regulation of peptide secretion GO:0002791 77 0.013
anatomical structure homeostasis GO:0060249 145 0.013
activation of mapk activity GO:0000187 59 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
chromatin modification GO:0016568 187 0.013
vitamin d biosynthetic process GO:0042368 3 0.013
multicellular organism growth GO:0035264 161 0.013
Mouse
protein tetramerization GO:0051262 23 0.013
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.013
Mouse
circadian rhythm GO:0007623 114 0.013
regulation of action potential GO:0098900 4 0.013
cell substrate adhesion GO:0031589 130 0.013
Mouse
b cell mediated immunity GO:0019724 71 0.013
oxidative demethylation GO:0070989 1 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
renal tubule development GO:0061326 87 0.013
Mouse
cellular biogenic amine metabolic process GO:0006576 28 0.013
striated muscle tissue development GO:0014706 293 0.013
regulation of circadian rhythm GO:0042752 58 0.013
glucan metabolic process GO:0044042 32 0.013
sulfur compound metabolic process GO:0006790 100 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
monocarboxylic acid catabolic process GO:0072329 27 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
Mouse
regulation of protein localization GO:0032880 231 0.012
Mouse
lipid oxidation GO:0034440 29 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
astrocyte activation GO:0048143 2 0.012
Mouse
binding of sperm to zona pellucida GO:0007339 34 0.012
anion transmembrane transport GO:0098656 71 0.012
covalent chromatin modification GO:0016569 163 0.012
ovulation from ovarian follicle GO:0001542 9 0.012
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
female gamete generation GO:0007292 74 0.012
Mouse
glycogen metabolic process GO:0005977 32 0.012
skeletal system development GO:0001501 356 0.012
vasoconstriction GO:0042310 27 0.012
Mouse
phosphatidylinositol mediated signaling GO:0048015 41 0.012
Mouse
organic hydroxy compound biosynthetic process GO:1901617 77 0.012
mesonephros development GO:0001823 97 0.012
Mouse
respiratory system development GO:0060541 190 0.012
sphingolipid metabolic process GO:0006665 45 0.012
regulation of organ growth GO:0046620 61 0.012
Mouse
actin mediated cell contraction GO:0070252 15 0.012
atp metabolic process GO:0046034 75 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
stem cell differentiation GO:0048863 268 0.012
unsaturated fatty acid metabolic process GO:0033559 31 0.012
sa node cell action potential GO:0086015 4 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
cellular response to carbohydrate stimulus GO:0071322 50 0.012
positive regulation of cytokine production GO:0001819 174 0.012
Mouse
chromatin organization GO:0006325 206 0.012
learning or memory GO:0007611 148 0.011
nucleoside catabolic process GO:0009164 206 0.011
regulation of peptide transport GO:0090087 91 0.011
positive regulation of immune effector process GO:0002699 107 0.011
cholesterol transport GO:0030301 38 0.011
regulation of angiogenesis GO:0045765 81 0.011
Rat
regulation of lymphocyte activation GO:0051249 240 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
Rat
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
Mouse
membrane organization GO:0061024 245 0.011
nucleoside phosphate metabolic process GO:0006753 338 0.011
atrial ventricular junction remodeling GO:0003294 2 0.011
adult behavior GO:0030534 135 0.011
protein import GO:0017038 101 0.011
positive regulation of organ growth GO:0046622 29 0.011
Mouse
kidney development GO:0001822 213 0.011
Mouse
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
positive regulation of cellular response to insulin stimulus GO:1900078 9 0.011
Mouse
gonad development GO:0008406 141 0.011
Mouse
negative regulation of cell development GO:0010721 169 0.011
membrane depolarization GO:0051899 64 0.011
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.011
Mouse
cellular protein complex assembly GO:0043623 116 0.011

Serpina3k disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.100
inherited metabolic disorder DOID:655 0 0.053
immune system disease DOID:2914 0 0.024
disease of anatomical entity DOID:7 0 0.024
blood coagulation disease DOID:1247 0 0.024
inherited blood coagulation disease DOID:2214 0 0.024
hematopoietic system disease DOID:74 0 0.024
cardiovascular system disease DOID:1287 0 0.017
nervous system disease DOID:863 0 0.017