Mus musculus

10 known processes

Serpina6

serine (or cysteine) peptidase inhibitor, clade A, member 6

(Aliases: AV104445,AI265318,Cbg)

Serpina6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.932
Mouse
vitamin d3 metabolic process GO:0070640 3 0.594
small molecule biosynthetic process GO:0044283 132 0.581
Mouse
fat soluble vitamin biosynthetic process GO:0042362 4 0.544
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.526
Mouse
regulation of hormone levels GO:0010817 211 0.512
Mouse
fatty acid metabolic process GO:0006631 121 0.483
Mouse
oxidative demethylation GO:0070989 1 0.481
cellular ketone metabolic process GO:0042180 84 0.463
Mouse
naphthalene metabolic process GO:0018931 1 0.403
regulation of secretion GO:0051046 274 0.396
Mouse
cellular lipid metabolic process GO:0044255 323 0.379
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.369
Mouse
cellular amino acid metabolic process GO:0006520 103 0.369
alcohol metabolic process GO:0006066 116 0.369
Mouse
cellular amine metabolic process GO:0044106 44 0.362
response to organic cyclic compound GO:0014070 198 0.354
monocarboxylic acid metabolic process GO:0032787 191 0.351
Mouse
regulation of tube size GO:0035150 57 0.339
Mouse
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.326
Mouse
regulation of system process GO:0044057 200 0.323
cellular alcohol metabolic process GO:0044107 3 0.318
protein maturation GO:0051604 176 0.309
Mouse
steroid metabolic process GO:0008202 119 0.307
response to phenylpropanoid GO:0080184 22 0.293
hormone metabolic process GO:0042445 86 0.285
Mouse
organic hydroxy compound biosynthetic process GO:1901617 77 0.275
vitamin d biosynthetic process GO:0042368 3 0.262
neutral lipid metabolic process GO:0006638 57 0.254
Mouse
carboxylic acid biosynthetic process GO:0046394 86 0.254
Mouse
response to stilbenoid GO:0035634 22 0.252
regulation of secretion by cell GO:1903530 249 0.244
Mouse
cofactor metabolic process GO:0051186 80 0.243
regulation of lipid metabolic process GO:0019216 118 0.235
Mouse
unsaturated fatty acid metabolic process GO:0033559 31 0.235
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.228
Mouse
cellular response to inorganic substance GO:0071241 37 0.225
amine metabolic process GO:0009308 45 0.222
circulatory system process GO:0003013 197 0.205
Mouse
positive regulation of steroid hormone secretion GO:2000833 2 0.202
organic acid biosynthetic process GO:0016053 86 0.200
Mouse
vitamin metabolic process GO:0006766 23 0.198
regulation of cellular ketone metabolic process GO:0010565 66 0.188
Mouse
metal ion homeostasis GO:0055065 189 0.187
response to inorganic substance GO:0010035 96 0.179
organic cyclic compound catabolic process GO:1901361 295 0.177
glycerolipid metabolic process GO:0046486 122 0.176
Mouse
lipid biosynthetic process GO:0008610 179 0.176
Mouse
hemostasis GO:0007599 78 0.175
positive regulation of secretion by cell GO:1903532 114 0.174
Mouse
cytokine production GO:0001816 319 0.173
Mouse
renal tubular secretion GO:0097254 2 0.172
regulation of cellular amine metabolic process GO:0033238 20 0.168
negative regulation of iron ion transport GO:0034757 1 0.164
hormone secretion GO:0046879 128 0.159
progesterone metabolic process GO:0042448 4 0.159
secondary alcohol metabolic process GO:1902652 3 0.156
lipid localization GO:0010876 126 0.154
regulation of systemic arterial blood pressure GO:0003073 61 0.154
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.153
Mouse
oxidation reduction process GO:0055114 342 0.151
fatty acid derivative metabolic process GO:1901568 33 0.151
blood coagulation GO:0007596 76 0.146
cellular homeostasis GO:0019725 240 0.145
cellular response to cadmium ion GO:0071276 3 0.144
cellular alcohol biosynthetic process GO:0044108 3 0.142
coagulation GO:0050817 78 0.142
regulation of protein localization GO:0032880 231 0.139
Mouse
response to insulin GO:0032868 100 0.138
Mouse
vasoconstriction GO:0042310 27 0.137
Mouse
steroid biosynthetic process GO:0006694 47 0.136
porphyrin containing compound metabolic process GO:0006778 22 0.135
negative regulation of cellular protein metabolic process GO:0032269 247 0.134
Mouse
positive regulation of estrogen secretion GO:2000863 1 0.131
regulation of blood vessel size GO:0050880 56 0.129
Mouse
fibrinolysis GO:0042730 3 0.128
cellular chemical homeostasis GO:0055082 215 0.127
blood circulation GO:0008015 195 0.124
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.123
epithelial cell proliferation GO:0050673 174 0.122
cellular response to hormone stimulus GO:0032870 150 0.122
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.122
regulation of blood vessel size by renin angiotensin GO:0002034 5 0.120
Mouse
cholesterol homeostasis GO:0042632 44 0.119
response to peptide hormone GO:0043434 127 0.119
Mouse
regulation of mapk cascade GO:0043408 248 0.117
Mouse
icosanoid metabolic process GO:0006690 33 0.116
naphthalene containing compound metabolic process GO:0090420 1 0.116
regulation of blood pressure GO:0008217 93 0.116
Mouse
arachidonic acid metabolic process GO:0019369 14 0.115
negative regulation of fibrinolysis GO:0051918 1 0.115
regulation of anatomical structure size GO:0090066 178 0.115
Mouse
regulation of hemostasis GO:1900046 28 0.107
negative regulation of protein metabolic process GO:0051248 282 0.106
Mouse
regulation of establishment of protein localization GO:0070201 181 0.105
Mouse
regulation of kinase activity GO:0043549 249 0.104
Mouse
negative regulation of response to wounding GO:1903035 77 0.104
muscle tissue development GO:0060537 308 0.103
response to cadmium ion GO:0046686 8 0.102
calcitriol biosynthetic process from calciol GO:0036378 3 0.102
carbohydrate metabolic process GO:0005975 230 0.101
Mouse
negative regulation of molecular function GO:0044092 258 0.100
Mouse
positive regulation of protein modification process GO:0031401 299 0.099
Mouse
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.099
Mouse
cellular response to metal ion GO:0071248 31 0.099
morphogenesis of a branching epithelium GO:0061138 193 0.099
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.098
response to organonitrogen compound GO:0010243 246 0.096
Mouse
fat soluble vitamin metabolic process GO:0006775 11 0.095
organonitrogen compound catabolic process GO:1901565 264 0.093
positive regulation of transferase activity GO:0051347 167 0.092
Mouse
regulation of estrogen secretion GO:2000861 1 0.092
alcohol biosynthetic process GO:0046165 43 0.090
long chain fatty acid metabolic process GO:0001676 26 0.089
protein secretion GO:0009306 111 0.086
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.085
renal system process GO:0003014 48 0.084
Mouse
cation transport GO:0006812 399 0.084
calcium ion homeostasis GO:0055074 127 0.082
estrogen secretion GO:0035937 1 0.082
cellular divalent inorganic cation homeostasis GO:0072503 127 0.082
monocarboxylic acid biosynthetic process GO:0072330 61 0.081
Mouse
regulation of cytokine production GO:0001817 266 0.081
Mouse
cation homeostasis GO:0055080 212 0.079
response to drug GO:0042493 75 0.079
protein processing GO:0016485 163 0.079
Mouse
multicellular organismal homeostasis GO:0048871 164 0.079
small gtpase mediated signal transduction GO:0007264 97 0.076
wound healing GO:0042060 157 0.076
gland development GO:0048732 330 0.076
lipid homeostasis GO:0055088 63 0.075
negative regulation of proteolysis GO:0045861 74 0.074
Mouse
response to nutrient levels GO:0031667 109 0.074
anion transport GO:0006820 177 0.074
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.074
regulation of protein secretion GO:0050708 82 0.073
Mouse
regulation of protein transport GO:0051223 163 0.072
Mouse
lipid transport GO:0006869 98 0.071
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.071
Mouse
negative regulation of growth GO:0045926 99 0.071
hematopoietic progenitor cell differentiation GO:0002244 143 0.070
negative regulation of endothelial cell migration GO:0010596 4 0.069
sterol metabolic process GO:0016125 58 0.068
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.066
regulation of epithelial cell proliferation GO:0050678 141 0.065
small molecule catabolic process GO:0044282 71 0.065
regulation of response to wounding GO:1903034 189 0.065
Mouse
folic acid containing compound metabolic process GO:0006760 3 0.064
positive regulation of kinase activity GO:0033674 155 0.063
Mouse
fat cell differentiation GO:0045444 160 0.063
response to extracellular stimulus GO:0009991 127 0.063
terpenoid metabolic process GO:0006721 25 0.062
energy reserve metabolic process GO:0006112 39 0.062
regulation of hormone secretion GO:0046883 88 0.060
lipid catabolic process GO:0016042 69 0.059
cellular nitrogen compound catabolic process GO:0044270 280 0.059
heme metabolic process GO:0042168 16 0.059
apoptotic signaling pathway GO:0097190 306 0.059
ameboidal type cell migration GO:0001667 128 0.059
cellular response to lipid GO:0071396 145 0.059
positive regulation of lipid metabolic process GO:0045834 40 0.058
Mouse
transmembrane transport GO:0055085 412 0.058
anatomical structure homeostasis GO:0060249 145 0.058
alpha amino acid metabolic process GO:1901605 59 0.058
myeloid cell differentiation GO:0030099 233 0.058
vascular process in circulatory system GO:0003018 62 0.057
Mouse
rhythmic process GO:0048511 174 0.057
Mouse
sequestering of calcium ion GO:0051208 18 0.056
defense response to other organism GO:0098542 197 0.056
ion transmembrane transport GO:0034220 361 0.056
negative regulation of protein processing GO:0010955 79 0.056
Mouse
response to organophosphorus GO:0046683 22 0.055
development of primary female sexual characteristics GO:0046545 73 0.055
Mouse
positive regulation of hormone secretion GO:0046887 38 0.055
chondrocyte differentiation GO:0002062 72 0.055
one carbon metabolic process GO:0006730 1 0.055
mapk cascade GO:0000165 281 0.055
Mouse
diterpenoid metabolic process GO:0016101 24 0.055
regulation of wound healing GO:0061041 40 0.054
cellular biogenic amine metabolic process GO:0006576 28 0.053
regulation of proteolysis GO:0030162 164 0.053
Mouse
regulation of protein processing GO:0070613 96 0.052
Mouse
cytoplasmic transport GO:0016482 234 0.052
purine nucleotide catabolic process GO:0006195 211 0.051
negative regulation of cell proliferation GO:0008285 296 0.051
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.050
Mouse
anion transmembrane transport GO:0098656 71 0.048
regulation of transferase activity GO:0051338 263 0.048
Mouse
respiratory system development GO:0060541 190 0.047
nucleotide metabolic process GO:0009117 332 0.047
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.047
regulation of blood coagulation GO:0030193 28 0.047
sulfur compound metabolic process GO:0006790 100 0.046
organic anion transport GO:0015711 137 0.045
tetrapyrrole metabolic process GO:0033013 22 0.045
response to molecule of bacterial origin GO:0002237 143 0.045
striated muscle tissue development GO:0014706 293 0.045
response to metal ion GO:0010038 47 0.045
ovulation GO:0030728 15 0.044
Mouse
male gamete generation GO:0048232 285 0.044
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.044
Mouse
regulation of protein kinase activity GO:0045859 232 0.044
Mouse
response to alkaloid GO:0043279 34 0.044
cartilage development GO:0051216 140 0.044
monosaccharide metabolic process GO:0005996 106 0.043
Mouse
negative regulation of homeostatic process GO:0032845 71 0.042
male gonad development GO:0008584 88 0.042
positive regulation of cytokine production GO:0001819 174 0.042
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.041
cellular response to external stimulus GO:0071496 88 0.041
cellular response to peptide hormone stimulus GO:0071375 92 0.041
Mouse
regulation of body fluid levels GO:0050878 162 0.041
positive regulation of secretion GO:0051047 130 0.041
Mouse
carbohydrate biosynthetic process GO:0016051 74 0.040
Mouse
liver development GO:0001889 66 0.040
heterocycle catabolic process GO:0046700 280 0.040
cellular ion homeostasis GO:0006873 165 0.040
response to peptide GO:1901652 136 0.040
Mouse
response to steroid hormone GO:0048545 56 0.040
cell substrate adhesion GO:0031589 130 0.040
Mouse
regulation of carbohydrate metabolic process GO:0006109 75 0.039
Mouse
striated muscle cell development GO:0055002 125 0.039
pigment metabolic process GO:0042440 32 0.039
endocrine process GO:0050886 39 0.039
Mouse
male sex differentiation GO:0046661 109 0.039
cellular metal ion homeostasis GO:0006875 151 0.039
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
sensory perception GO:0007600 245 0.038
establishment of blood nerve barrier GO:0008065 3 0.038
Mouse
leukocyte differentiation GO:0002521 342 0.038
regulation of phospholipase c activity GO:1900274 3 0.038
positive regulation of mapk cascade GO:0043410 170 0.037
Mouse
testosterone biosynthetic process GO:0061370 2 0.037
morphogenesis of a branching structure GO:0001763 203 0.037
Mouse
maternal process involved in female pregnancy GO:0060135 32 0.037
positive regulation of protein transport GO:0051222 93 0.037
Mouse
cytokine secretion GO:0050663 72 0.036
Mouse
benzene containing compound metabolic process GO:0042537 5 0.036
regulation of cell activation GO:0050865 289 0.036
response to lipopolysaccharide GO:0032496 128 0.036
cellular response to extracellular stimulus GO:0031668 81 0.036
kidney epithelium development GO:0072073 121 0.036
Mouse
muscle cell differentiation GO:0042692 261 0.036
Mouse
angiogenesis GO:0001525 201 0.036
divalent inorganic cation homeostasis GO:0072507 138 0.036
myosin filament organization GO:0031033 3 0.035
glucose homeostasis GO:0042593 128 0.035
acylglycerol metabolic process GO:0006639 55 0.035
Mouse
gonad development GO:0008406 141 0.035
Mouse
regulation of glucose metabolic process GO:0010906 60 0.035
Mouse
isoprenoid metabolic process GO:0006720 29 0.035
female sex differentiation GO:0046660 84 0.035
Mouse
regulation of homeostatic process GO:0032844 182 0.035
extrinsic apoptotic signaling pathway GO:0097191 126 0.034
regulation of coagulation GO:0050818 31 0.034
peptidyl amino acid modification GO:0018193 336 0.034
Mouse
organic acid transport GO:0015849 101 0.034
very long chain fatty acid metabolic process GO:0000038 8 0.034
amino acid transmembrane transport GO:0003333 37 0.034
positive regulation of programmed cell death GO:0043068 218 0.034
endothelial cell differentiation GO:0045446 41 0.034
Mouse
glial cell differentiation GO:0010001 131 0.034
Mouse
renal system development GO:0072001 225 0.034
Mouse
androgen biosynthetic process GO:0006702 4 0.033
nitrogen compound transport GO:0071705 271 0.033
nucleoside phosphate metabolic process GO:0006753 338 0.033
regulation of protein kinase c activity GO:1900019 1 0.033
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.033
extracellular structure organization GO:0043062 148 0.033
Mouse
energy derivation by oxidation of organic compounds GO:0015980 77 0.033
regulation of lipid biosynthetic process GO:0046890 54 0.033
Mouse
secondary metabolic process GO:0019748 18 0.032
forebrain development GO:0030900 302 0.032
blood vessel morphogenesis GO:0048514 285 0.032
cellular macromolecule catabolic process GO:0044265 206 0.032
regulation of erk1 and erk2 cascade GO:0070372 71 0.032
cellular calcium ion homeostasis GO:0006874 119 0.032
progesterone biosynthetic process GO:0006701 1 0.031
carbohydrate derivative biosynthetic process GO:1901137 183 0.031
Mouse
positive regulation of systemic arterial blood pressure GO:0003084 9 0.031
Mouse
regulation of membrane potential GO:0042391 192 0.031
connective tissue development GO:0061448 179 0.031
regulation of cytoplasmic transport GO:1903649 112 0.031
divalent metal ion transport GO:0070838 172 0.031
aromatic compound catabolic process GO:0019439 286 0.031
positive regulation of blood pressure GO:0045777 21 0.031
Mouse
regulation of interleukin 8 production GO:0032677 3 0.031
carbohydrate derivative catabolic process GO:1901136 231 0.030
epidermis development GO:0008544 187 0.030
cellular protein catabolic process GO:0044257 155 0.030
positive regulation of apoptotic process GO:0043065 217 0.030
regulation of ossification GO:0030278 112 0.030
dibenzo p dioxin metabolic process GO:0018894 1 0.030
macromolecule catabolic process GO:0009057 281 0.030
maintenance of location GO:0051235 89 0.030
organ regeneration GO:0031100 2 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.029
regulation of cellular catabolic process GO:0031329 242 0.029
regulation of hydrolase activity GO:0051336 246 0.029
Mouse
spermatogenesis GO:0007283 284 0.029
Mouse
regulation of peptide secretion GO:0002791 77 0.028
saturated monocarboxylic acid metabolic process GO:0032788 2 0.028
female gonad development GO:0008585 71 0.028
Mouse
vitamin biosynthetic process GO:0009110 7 0.028
regulation of wnt signaling pathway GO:0030111 123 0.028
cellular response to insulin stimulus GO:0032869 78 0.028
Mouse
interleukin 8 production GO:0032637 4 0.028
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.028
linoleic acid metabolic process GO:0043651 6 0.028
embryonic placenta development GO:0001892 98 0.028
regulation of lipid transport GO:0032368 36 0.027
skeletal system development GO:0001501 356 0.027
posttranscriptional regulation of gene expression GO:0010608 155 0.027
heart process GO:0003015 94 0.027
multicellular organism growth GO:0035264 161 0.027
Mouse
negative regulation of immune system process GO:0002683 209 0.027
response to testosterone GO:0033574 3 0.027
peptide hormone secretion GO:0030072 109 0.027
cholesterol metabolic process GO:0008203 56 0.027
Mouse
regulation of peptidyl serine phosphorylation GO:0033135 39 0.026
Mouse
regulation of ion transport GO:0043269 215 0.026
cell type specific apoptotic process GO:0097285 268 0.026
Mouse
development of primary male sexual characteristics GO:0046546 88 0.026
protein localization to organelle GO:0033365 185 0.026
cell adhesion GO:0007155 329 0.026
Mouse
ribose phosphate metabolic process GO:0019693 291 0.026
placenta development GO:0001890 140 0.026
positive regulation of wound healing GO:0090303 17 0.026
phospholipid metabolic process GO:0006644 87 0.026
cytosolic calcium ion homeostasis GO:0051480 70 0.025
hexose metabolic process GO:0019318 98 0.025
Mouse
cellular response to peptide GO:1901653 92 0.025
Mouse
regulation of steroid biosynthetic process GO:0050810 26 0.025
carbohydrate homeostasis GO:0033500 128 0.025
peptidyl serine phosphorylation GO:0018105 74 0.025
Mouse
cell growth GO:0016049 130 0.025
muscle cell development GO:0055001 133 0.025
cell cell junction organization GO:0045216 72 0.025
defense response to bacterium GO:0042742 119 0.025
inter male aggressive behavior GO:0002121 3 0.024
positive regulation of coagulation GO:0050820 13 0.024
regulation of intracellular transport GO:0032386 159 0.024
striated muscle myosin thick filament assembly GO:0071688 1 0.024
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.024
Mouse
positive regulation of angiogenesis GO:0045766 46 0.024
inositol lipid mediated signaling GO:0048017 41 0.024
Mouse
organelle assembly GO:0070925 177 0.024
generation of precursor metabolites and energy GO:0006091 103 0.024
labyrinthine layer development GO:0060711 49 0.024
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 4 0.024
regulation of microvillus assembly GO:0032534 3 0.024
female gamete generation GO:0007292 74 0.024
Mouse
negative regulation of protein maturation GO:1903318 79 0.024
Mouse
regulation of cytokine secretion GO:0050707 61 0.024
Mouse
polyol biosynthetic process GO:0046173 13 0.024
organic hydroxy compound transport GO:0015850 93 0.023
regulation of inflammatory response GO:0050727 147 0.023
Mouse
cofactor transport GO:0051181 4 0.023
regulation of peptide transport GO:0090087 91 0.023
regulation of ion homeostasis GO:2000021 64 0.023
regulation of adaptive immune response GO:0002819 90 0.023
response to acid chemical GO:0001101 111 0.023
nucleoside metabolic process GO:0009116 246 0.023
multicellular organismal signaling GO:0035637 91 0.023
erk1 and erk2 cascade GO:0070371 77 0.023
regulation of reactive oxygen species metabolic process GO:2000377 40 0.023
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.023
polyol metabolic process GO:0019751 26 0.022
skeletal muscle organ development GO:0060538 163 0.022
nuclear transport GO:0051169 139 0.022
sterol homeostasis GO:0055092 45 0.022
transmission of nerve impulse GO:0019226 76 0.022
multi multicellular organism process GO:0044706 109 0.022
inorganic ion transmembrane transport GO:0098660 234 0.022
purine containing compound catabolic process GO:0072523 213 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
negative regulation of coagulation GO:0050819 11 0.022
epithelial cell migration GO:0010631 63 0.022
cholesterol transport GO:0030301 38 0.022
activation of adenylate cyclase activity GO:0007190 4 0.022
protein catabolic process GO:0030163 221 0.022
coenzyme metabolic process GO:0006732 52 0.022
negative regulation of hemostasis GO:1900047 11 0.022
response to estrogen GO:0043627 24 0.021
organelle fission GO:0048285 170 0.021
muscle cell proliferation GO:0033002 52 0.021
Mouse
cellular response to biotic stimulus GO:0071216 92 0.021
stem cell differentiation GO:0048863 268 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
cellular modified amino acid metabolic process GO:0006575 63 0.021
cognition GO:0050890 149 0.021
reactive nitrogen species metabolic process GO:2001057 0 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
response to starvation GO:0042594 65 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
Mouse
retinal blood vessel morphogenesis GO:0061304 3 0.020
regulation of complement activation classical pathway GO:0030450 1 0.020
action potential GO:0001508 78 0.020
regulation of fatty acid biosynthetic process GO:0042304 12 0.020
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.020
xenobiotic catabolic process GO:0042178 1 0.020
ketone body metabolic process GO:1902224 3 0.020
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 15 0.020
Mouse
urogenital system development GO:0001655 261 0.020
Mouse
thermosensory behavior GO:0040040 1 0.020
single organism nuclear import GO:1902593 95 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
regulation of intestinal cholesterol absorption GO:0030300 4 0.020
cellular response to gonadotropin stimulus GO:0071371 4 0.020
cytokine mediated signaling pathway GO:0019221 115 0.019
positive regulation of nervous system development GO:0051962 221 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
ensheathment of neurons GO:0007272 76 0.019
astrocyte activation GO:0048143 2 0.019
Mouse
intracellular receptor signaling pathway GO:0030522 74 0.019
locomotory behavior GO:0007626 195 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
cellular protein complex assembly GO:0043623 116 0.019
protein import into nucleus GO:0006606 95 0.019
nephron development GO:0072006 109 0.019
Mouse
leukocyte mediated immunity GO:0002443 174 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
positive regulation of map kinase activity GO:0043406 84 0.019
response to oxidative stress GO:0006979 123 0.019
medium chain fatty acid metabolic process GO:0051791 1 0.019
hormone biosynthetic process GO:0042446 16 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
regulation of carbohydrate biosynthetic process GO:0043255 40 0.018
Mouse
divalent inorganic cation transport GO:0072511 178 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
sequestering of metal ion GO:0051238 19 0.018
toxin metabolic process GO:0009404 5 0.018
monosaccharide biosynthetic process GO:0046364 44 0.018
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.018
endothelial cell migration GO:0043542 44 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.018
negative regulation of peptidase activity GO:0010466 46 0.018
Mouse
extracellular matrix organization GO:0030198 147 0.018
Mouse
heart morphogenesis GO:0003007 178 0.018
lymphocyte mediated immunity GO:0002449 139 0.018
response to transition metal nanoparticle GO:1990267 11 0.018
c21 steroid hormone biosynthetic process GO:0006700 3 0.018
endocrine system development GO:0035270 98 0.018
regulation of stress activated mapk cascade GO:0032872 69 0.018
lung development GO:0030324 164 0.017
phenol containing compound metabolic process GO:0018958 60 0.017
negative regulation of lipid metabolic process GO:0045833 30 0.017
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
c21 steroid hormone metabolic process GO:0008207 7 0.017
regulation of metal ion transport GO:0010959 106 0.017
skin development GO:0043588 220 0.017
peptide secretion GO:0002790 114 0.017
digestive system development GO:0055123 200 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
Mouse
nephron epithelium development GO:0072009 92 0.017
Mouse
transition metal ion transport GO:0000041 38 0.017
steroid hormone secretion GO:0035929 9 0.017
bone development GO:0060348 120 0.017
endothelium development GO:0003158 45 0.017
Mouse
muscle contraction GO:0006936 101 0.017
Mouse
negative regulation of cytokine production GO:0001818 84 0.017
astrocyte differentiation GO:0048708 43 0.017
Mouse
intracellular protein transport GO:0006886 204 0.017
protein ubiquitination GO:0016567 171 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.017
negative regulation of t cell activation GO:0050868 65 0.017
regulation of neurotransmitter levels GO:0001505 87 0.017
rho protein signal transduction GO:0007266 32 0.017
protein import GO:0017038 101 0.017
cytokine production involved in immune response GO:0002367 34 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.017
hexose biosynthetic process GO:0019319 39 0.017
Mouse
cell division GO:0051301 120 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017
ribonucleotide metabolic process GO:0009259 291 0.016
regulation of muscle tissue development GO:1901861 97 0.016
cellular response to glucose stimulus GO:0071333 45 0.016
learning GO:0007612 98 0.016
negative regulation of protein modification process GO:0031400 163 0.016

Serpina6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.617
inherited metabolic disorder DOID:655 0 0.222
lipid metabolism disorder DOID:3146 0 0.162
steroid inherited metabolic disorder DOID:1701 0 0.162
disease of anatomical entity DOID:7 0 0.023
vascular disease DOID:178 0 0.023
cardiovascular system disease DOID:1287 0 0.023
congenital adrenal hyperplasia DOID:0050811 0 0.020
immune system disease DOID:2914 0 0.019
blood coagulation disease DOID:1247 0 0.019
hematopoietic system disease DOID:74 0 0.019
nervous system disease DOID:863 0 0.017