Mus musculus

48 known processes

Serping1

serine (or cysteine) peptidase inhibitor, clade G, member 1

(Aliases: C1INH,C1nh)

Serping1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of proteolysis GO:0045861 74 0.718
complement activation GO:0006956 16 0.698
Human
regulation of peptidase activity GO:0052547 96 0.585
protein activation cascade GO:0072376 19 0.479
Human
angiogenesis GO:0001525 201 0.460
Mouse
protein processing GO:0016485 163 0.456
positive regulation of activation of membrane attack complex GO:0001970 2 0.418
amine metabolic process GO:0009308 45 0.401
protein maturation GO:0051604 176 0.386
negative regulation of protein metabolic process GO:0051248 282 0.385
regulation of endopeptidase activity GO:0052548 89 0.354
response to organic cyclic compound GO:0014070 198 0.338
regulation of proteolysis GO:0030162 164 0.319
immune effector process GO:0002252 321 0.283
Human
positive regulation of protein phosphorylation GO:0001934 242 0.278
establishment of blood nerve barrier GO:0008065 3 0.274
negative regulation of hydrolase activity GO:0051346 71 0.274
innate immune response GO:0045087 157 0.268
Human
carbohydrate metabolic process GO:0005975 230 0.264
response to lipopolysaccharide GO:0032496 128 0.263
negative regulation of endopeptidase activity GO:0010951 44 0.257
regulation of cellular ketone metabolic process GO:0010565 66 0.245
humoral immune response GO:0006959 57 0.244
Human
mapk cascade GO:0000165 281 0.244
regulation of cellular amine metabolic process GO:0033238 20 0.234
cellular ketone metabolic process GO:0042180 84 0.227
extracellular matrix organization GO:0030198 147 0.219
Mouse
ossification GO:0001503 216 0.215
monosaccharide metabolic process GO:0005996 106 0.215
cellular lipid metabolic process GO:0044255 323 0.214
glucose metabolic process GO:0006006 92 0.213
response to steroid hormone GO:0048545 56 0.207
response to molecule of bacterial origin GO:0002237 143 0.200
kidney development GO:0001822 213 0.199
regulation of blood pressure GO:0008217 93 0.198
Mouse
regulation of cell motility GO:2000145 236 0.192
negative regulation of tooth mineralization GO:0070171 1 0.190
regulation of angiogenesis GO:0045765 81 0.188
Mouse
type b pancreatic cell proliferation GO:0044342 10 0.183
regulation of cellular amino acid metabolic process GO:0006521 5 0.180
cell adhesion GO:0007155 329 0.178
negative regulation of cell migration GO:0030336 59 0.177
response to peptide GO:1901652 136 0.177
oxidation reduction process GO:0055114 342 0.166
regulation of epithelial cell proliferation GO:0050678 141 0.164
Mouse
cellular amine metabolic process GO:0044106 44 0.163
endothelium development GO:0003158 45 0.160
negative regulation of peptidase activity GO:0010466 46 0.159
carbohydrate homeostasis GO:0033500 128 0.157
regulation of cytokine production GO:0001817 266 0.156
Mouse
positive regulation of protein kinase b signaling GO:0051897 32 0.154
regulation of defense response GO:0031347 233 0.154
Human
triglyceride metabolic process GO:0006641 51 0.150
cellular response to growth factor stimulus GO:0071363 197 0.149
myeloid cell differentiation GO:0030099 233 0.144
peptidyl amino acid modification GO:0018193 336 0.143
response to organonitrogen compound GO:0010243 246 0.142
epithelial tube morphogenesis GO:0060562 303 0.141
blood vessel morphogenesis GO:0048514 285 0.141
Mouse
regulation of glucose metabolic process GO:0010906 60 0.140
glycerolipid metabolic process GO:0046486 122 0.139
regulation of vasculature development GO:1901342 88 0.132
Mouse
chondroitin sulfate proteoglycan metabolic process GO:0050654 20 0.129
cellular response to peptide GO:1901653 92 0.127
positive regulation of behavior GO:0048520 40 0.126
glucose homeostasis GO:0042593 128 0.125
negative regulation of cellular protein metabolic process GO:0032269 247 0.125
cell substrate adhesion GO:0031589 130 0.124
regulation of cell migration GO:0030334 219 0.121
macromolecule glycosylation GO:0043413 55 0.119
response to interferon gamma GO:0034341 34 0.118
positive regulation of cytokine production GO:0001819 174 0.117
Mouse
positive regulation of mapk cascade GO:0043410 170 0.117
cellular response to cytokine stimulus GO:0071345 189 0.116
regulation of tooth mineralization GO:0070170 2 0.114
positive regulation of protein kinase c activity GO:1900020 1 0.113
cell matrix adhesion GO:0007160 68 0.112
positive regulation of nervous system development GO:0051962 221 0.112
peptidyl serine modification GO:0018209 83 0.110
astrocyte activation GO:0048143 2 0.109
regulation of hydrolase activity GO:0051336 246 0.108
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.108
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.106
negative regulation of protein maturation GO:1903318 79 0.106
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.103
positive regulation of chemotaxis GO:0050921 38 0.100
ovarian follicle rupture GO:0001543 2 0.100
regulation of transferase activity GO:0051338 263 0.098
hexose metabolic process GO:0019318 98 0.098
morphogenesis of a branching epithelium GO:0061138 193 0.098
inflammatory response GO:0006954 244 0.097
Human
regulation of protein processing GO:0070613 96 0.097
lymphocyte mediated immunity GO:0002449 139 0.096
peptide cross linking GO:0018149 10 0.094
negative regulation of odontogenesis GO:0042483 3 0.094
organic hydroxy compound metabolic process GO:1901615 203 0.094
blood circulation GO:0008015 195 0.093
Mouse
lipid biosynthetic process GO:0008610 179 0.093
response to peptide hormone GO:0043434 127 0.091
chemotaxis GO:0006935 247 0.091
negative regulation of phosphorus metabolic process GO:0010563 184 0.089
gluconeogenesis GO:0006094 39 0.089
regulation of fatty acid metabolic process GO:0019217 28 0.088
cellular response to organonitrogen compound GO:0071417 145 0.088
cellular response to hormone stimulus GO:0032870 150 0.086
glycoprotein metabolic process GO:0009100 116 0.086
production of molecular mediator of immune response GO:0002440 103 0.085
lung development GO:0030324 164 0.085
negative regulation of molecular function GO:0044092 258 0.085
endocrine process GO:0050886 39 0.083
Mouse
regulation of lipid metabolic process GO:0019216 118 0.082
cytokine production GO:0001816 319 0.082
Mouse
regulation of hormone levels GO:0010817 211 0.082
negative regulation of cell proliferation GO:0008285 296 0.081
Mouse
regulation of carbohydrate metabolic process GO:0006109 75 0.080
negative regulation of protein processing GO:0010955 79 0.080
regulation of protein kinase activity GO:0045859 232 0.079
epithelial cell proliferation GO:0050673 174 0.079
Mouse
regulation of kinase activity GO:0043549 249 0.079
cholesterol metabolic process GO:0008203 56 0.078
regulation of inflammatory response GO:0050727 147 0.078
Human
gland development GO:0048732 330 0.078
Mouse
positive regulation of angiogenesis GO:0045766 46 0.076
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.073
neutral lipid metabolic process GO:0006638 57 0.072
camera type eye development GO:0043010 266 0.072
positive regulation of transferase activity GO:0051347 167 0.072
sulfur compound metabolic process GO:0006790 100 0.072
positive regulation of protein modification process GO:0031401 299 0.070
response to insulin GO:0032868 100 0.070
regulation of cell growth GO:0001558 91 0.070
positive regulation of neutrophil migration GO:1902624 12 0.070
terpenoid metabolic process GO:0006721 25 0.069
female sex differentiation GO:0046660 84 0.069
positive regulation of inflammatory response GO:0050729 47 0.069
muscle tissue development GO:0060537 308 0.068
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.067
chondroitin sulfate metabolic process GO:0030204 17 0.066
urogenital system development GO:0001655 261 0.066
Mouse
mucopolysaccharide metabolic process GO:1903510 25 0.066
acylglycerol metabolic process GO:0006639 55 0.065
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.065
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.065
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.064
small molecule biosynthetic process GO:0044283 132 0.064
lateral line system development GO:0048925 1 0.063
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.063
renal system development GO:0072001 225 0.063
response to growth factor GO:0070848 198 0.062
morphogenesis of a branching structure GO:0001763 203 0.062
response to inorganic substance GO:0010035 96 0.062
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.062
regulation of mapk cascade GO:0043408 248 0.061
regulation of apoptotic signaling pathway GO:2001233 197 0.061
glial cell differentiation GO:0010001 131 0.059
embryonic organ morphogenesis GO:0048562 276 0.059
response to oxidative stress GO:0006979 123 0.058
positive regulation of cellular amine metabolic process GO:0033240 5 0.058
respiratory tube development GO:0030323 167 0.057
response to acid chemical GO:0001101 111 0.057
cellular response to insulin stimulus GO:0032869 78 0.056
multicellular organism growth GO:0035264 161 0.056
respiratory system development GO:0060541 190 0.056
cellular amino acid metabolic process GO:0006520 103 0.056
negative regulation of cell motility GO:2000146 61 0.055
cellular response to peptide hormone stimulus GO:0071375 92 0.055
endothelial cell development GO:0001885 20 0.054
long chain fatty acid import GO:0044539 2 0.054
epidermis development GO:0008544 187 0.054
circulatory system process GO:0003013 197 0.053
Mouse
nephron development GO:0072006 109 0.053
peptidyl tyrosine modification GO:0018212 145 0.052
skin development GO:0043588 220 0.052
adaptive immune response GO:0002250 155 0.052
fatty acid metabolic process GO:0006631 121 0.052
negative regulation of protein phosphorylation GO:0001933 126 0.052
wound healing GO:0042060 157 0.051
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.050
negative regulation of phosphorylation GO:0042326 166 0.050
hexose transport GO:0008645 56 0.049
proteoglycan metabolic process GO:0006029 38 0.049
brown fat cell differentiation GO:0050873 36 0.049
regulation of protein maturation GO:1903317 96 0.049
peptidyl tyrosine phosphorylation GO:0018108 143 0.048
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.047
protein kinase b signaling GO:0043491 74 0.047
epithelial cell development GO:0002064 159 0.047
developmental growth involved in morphogenesis GO:0060560 138 0.047
fat cell differentiation GO:0045444 160 0.047
kidney epithelium development GO:0072073 121 0.046
response to corticosteroid GO:0031960 20 0.046
response to osmotic stress GO:0006970 21 0.045
regulation of cellular response to growth factor stimulus GO:0090287 82 0.045
regulation of gluconeogenesis GO:0006111 30 0.045
response to monosaccharide GO:0034284 67 0.044
regulation of anatomical structure size GO:0090066 178 0.044
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.044
sensory system development GO:0048880 3 0.044
connective tissue development GO:0061448 179 0.043
glycosaminoglycan metabolic process GO:0030203 34 0.043
activation of immune response GO:0002253 138 0.043
Human
cell chemotaxis GO:0060326 81 0.043
diterpenoid metabolic process GO:0016101 24 0.043
cell cell adhesion GO:0098609 41 0.042
negative regulation of protein modification process GO:0031400 163 0.042
intrinsic apoptotic signaling pathway GO:0097193 132 0.042
positive regulation of glucose transport GO:0010828 16 0.042
regulation of cellular response to insulin stimulus GO:1900076 30 0.041
nucleoside phosphate metabolic process GO:0006753 338 0.041
gliogenesis GO:0042063 141 0.041
cytokine mediated signaling pathway GO:0019221 115 0.040
activation of nf kappab inducing kinase activity GO:0007250 4 0.040
positive regulation of growth GO:0045927 104 0.040
small gtpase mediated signal transduction GO:0007264 97 0.040
positive regulation of kinase activity GO:0033674 155 0.040
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.040
peptide cross linking via chondroitin 4 sulfate glycosaminoglycan GO:0019800 8 0.039
sensory organ morphogenesis GO:0090596 242 0.039
branching morphogenesis of an epithelial tube GO:0048754 159 0.038
negative regulation of intracellular signal transduction GO:1902532 167 0.038
spermatogenesis GO:0007283 284 0.038
defense response to other organism GO:0098542 197 0.038
female gonad development GO:0008585 71 0.037
positive regulation of protein activation cascade GO:2000259 2 0.037
regulation of secretion GO:0051046 274 0.036
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.036
entry into other organism involved in symbiotic interaction GO:0051828 15 0.036
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.036
negative regulation of epithelial cell proliferation GO:0050680 64 0.035
Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.035
homeostasis of number of cells GO:0048872 210 0.035
hormone metabolic process GO:0042445 86 0.035
negative regulation of phosphate metabolic process GO:0045936 184 0.035
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.035
regulation of protein secretion GO:0050708 82 0.035
glucocorticoid metabolic process GO:0008211 9 0.034
striated muscle tissue development GO:0014706 293 0.034
regulation of complement activation GO:0030449 7 0.034
Human
monosaccharide biosynthetic process GO:0046364 44 0.034
response to alcohol GO:0097305 48 0.034
response to nutrient levels GO:0031667 109 0.034
neuron death GO:0070997 154 0.034
positive regulation of proteolysis GO:0045862 85 0.033
nucleotide metabolic process GO:0009117 332 0.033
regulation of organ morphogenesis GO:2000027 144 0.033
positive regulation of cell development GO:0010720 237 0.033
hexose biosynthetic process GO:0019319 39 0.033
response to transforming growth factor beta GO:0071559 88 0.033
positive regulation of apoptotic process GO:0043065 217 0.033
ovulation cycle GO:0042698 59 0.033
response to extracellular stimulus GO:0009991 127 0.032
cellular response to organic cyclic compound GO:0071407 87 0.032
negative regulation of immune system process GO:0002683 209 0.032
Human
astrocyte differentiation GO:0048708 43 0.032
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.032
regulation of fat cell differentiation GO:0045598 81 0.032
regulation of osteoblast differentiation GO:0045667 67 0.031
cartilage development GO:0051216 140 0.031
extracellular structure organization GO:0043062 148 0.031
Mouse
renal system process GO:0003014 48 0.030
Mouse
nephron epithelium development GO:0072009 92 0.030
apoptotic signaling pathway GO:0097190 306 0.030
entry into host GO:0044409 15 0.030
monosaccharide transport GO:0015749 58 0.029
regulation of protein stability GO:0031647 52 0.029
negative regulation of platelet derived growth factor receptor alpha signaling pathway GO:2000584 2 0.029
regulation of protein kinase b signaling GO:0051896 56 0.029
glucose transport GO:0015758 56 0.028
regulation of ras protein signal transduction GO:0046578 114 0.028
isoprenoid metabolic process GO:0006720 29 0.028
response to radiation GO:0009314 165 0.028
negative regulation of carbohydrate metabolic process GO:0045912 19 0.028
muscle cell differentiation GO:0042692 261 0.028
regulation of cholesterol metabolic process GO:0090181 14 0.028
positive regulation of cell projection organization GO:0031346 95 0.028
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.028
positive regulation of apoptotic cell clearance GO:2000427 3 0.027
tooth mineralization GO:0034505 9 0.027
cellular response to steroid hormone stimulus GO:0071383 33 0.027
negative regulation of blood vessel morphogenesis GO:2000181 25 0.027
Mouse
regulation of response to wounding GO:1903034 189 0.027
Human
macromolecule catabolic process GO:0009057 281 0.027
positive regulation of endopeptidase activity GO:0010950 43 0.027
nitrogen compound transport GO:0071705 271 0.027
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.026
Mouse
leukocyte tethering or rolling GO:0050901 3 0.026
insulin receptor signaling pathway GO:0008286 49 0.026
muscle cell proliferation GO:0033002 52 0.026
Mouse
cellular protein catabolic process GO:0044257 155 0.026
development of primary sexual characteristics GO:0045137 143 0.026
response to metal ion GO:0010038 47 0.026
anatomical structure homeostasis GO:0060249 145 0.026
cell growth GO:0016049 130 0.025
alcohol metabolic process GO:0006066 116 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
retinoid metabolic process GO:0001523 24 0.025
positive regulation of protein kinase activity GO:0045860 144 0.025
neutrophil migration GO:1990266 37 0.025
protein glycosylation GO:0006486 55 0.025
skeletal system morphogenesis GO:0048705 203 0.025
nephron tubule development GO:0072080 84 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.024
regulation of renal output by angiotensin GO:0002019 2 0.024
negative regulation of gluconeogenesis GO:0045721 9 0.024
regulation of glucose transport GO:0010827 32 0.024
metanephric glomerular visceral epithelial cell development GO:0072249 2 0.024
adiponectin secretion GO:0070162 2 0.024
skin morphogenesis GO:0043589 38 0.024
entry into host cell GO:0030260 15 0.024
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.024
defense response to gram positive bacterium GO:0050830 50 0.024
regulation of platelet derived growth factor receptor alpha signaling pathway GO:2000583 2 0.024
regulation of cell projection organization GO:0031344 206 0.024
transmembrane transport GO:0055085 412 0.024
heart morphogenesis GO:0003007 178 0.023
negative regulation of apoptotic signaling pathway GO:2001234 104 0.023
hormone secretion GO:0046879 128 0.023
carbohydrate transport GO:0008643 62 0.023
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.023
cellular homeostasis GO:0019725 240 0.023
glycosylation GO:0070085 62 0.023
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.023
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.023
regulation of lymphocyte mediated immunity GO:0002706 84 0.022
regulation of tube size GO:0035150 57 0.022
Mouse
regulation of cell size GO:0008361 72 0.022
carbohydrate biosynthetic process GO:0016051 74 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
regulation of protein activation cascade GO:2000257 7 0.022
Human
aminoglycan metabolic process GO:0006022 34 0.022
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.022
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.022
phagocytosis GO:0006909 66 0.022
cell type specific apoptotic process GO:0097285 268 0.021
male gamete generation GO:0048232 285 0.021
immunoglobulin mediated immune response GO:0016064 69 0.021
engulfment of apoptotic cell GO:0043652 3 0.021
cellular response to molecule of bacterial origin GO:0071219 83 0.021
cellular response to monosaccharide stimulus GO:0071326 47 0.021
regulation of cell adhesion GO:0030155 154 0.021
regulation of acute inflammatory response GO:0002673 27 0.021
Human
regulation of secretion by cell GO:1903530 249 0.021
regulation of neuron projection development GO:0010975 169 0.020
interleukin 27 mediated signaling pathway GO:0070106 1 0.020
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.020
aromatic compound catabolic process GO:0019439 286 0.020
peptidyl serine phosphorylation GO:0018105 74 0.020
regulation of neutrophil chemotaxis GO:0090022 14 0.020
metanephric glomerular epithelium development GO:0072244 3 0.019
nuclear import GO:0051170 95 0.019
cerebellum development GO:0021549 77 0.019
movement in host environment GO:0052126 15 0.019
cellular response to glucocorticoid stimulus GO:0071385 13 0.019
mitochondrion organization GO:0007005 134 0.019
epithelium migration GO:0090132 63 0.019
glycoprotein biosynthetic process GO:0009101 89 0.019
regulation of neuron death GO:1901214 134 0.019
nephron morphogenesis GO:0072028 69 0.018
stem cell differentiation GO:0048863 268 0.018
regulation of neuron differentiation GO:0045664 281 0.018
epithelial cell migration GO:0010631 63 0.018
lipid catabolic process GO:0016042 69 0.018
fat soluble vitamin biosynthetic process GO:0042362 4 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
complement activation lectin pathway GO:0001867 5 0.018
Human
peptide secretion GO:0002790 114 0.018
neuron apoptotic process GO:0051402 142 0.018
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.018
positive regulation of complement activation GO:0045917 2 0.018
formation of primary germ layer GO:0001704 77 0.018
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.018
Mouse
tissue homeostasis GO:0001894 115 0.018
fatty acid oxidation GO:0019395 28 0.017
metencephalon development GO:0022037 89 0.017
negative regulation of viral entry into host cell GO:0046597 10 0.017
regulation of transmission of nerve impulse GO:0051969 1 0.017
regulation of adaptive immune response GO:0002819 90 0.017
positive regulation of peptidase activity GO:0010952 49 0.017
hindbrain morphogenesis GO:0021575 46 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
limb development GO:0060173 166 0.017
protein localization to organelle GO:0033365 185 0.017
positive regulation of cytokine secretion GO:0050715 41 0.017
response to decreased oxygen levels GO:0036293 59 0.017
response to purine containing compound GO:0014074 28 0.017
negative regulation of ossification GO:0030279 49 0.017
mineralocorticoid biosynthetic process GO:0006705 1 0.017
ear development GO:0043583 200 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.016
response to reactive oxygen species GO:0000302 56 0.016
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
sterol metabolic process GO:0016125 58 0.016
positive regulation of glucose import GO:0046326 14 0.016
actin cytoskeleton organization GO:0030036 220 0.016
response to nutrient GO:0007584 12 0.016
positive regulation of endocytosis GO:0045807 42 0.016
regulation of cysteine type endopeptidase activity GO:2000116 65 0.016
regulation of lipid biosynthetic process GO:0046890 54 0.016
skeletal system development GO:0001501 356 0.016
b cell mediated immunity GO:0019724 71 0.016
establishment or maintenance of cell polarity GO:0007163 86 0.016
negative regulation of kinase activity GO:0033673 81 0.016
odontogenesis GO:0042476 78 0.016
interleukin 8 production GO:0032637 4 0.016
cellular response to interferon gamma GO:0071346 25 0.016
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
defense response to virus GO:0051607 68 0.016
immunoglobulin production GO:0002377 73 0.015
regulation of phospholipid biosynthetic process GO:0071071 3 0.015
establishment of tissue polarity GO:0007164 28 0.015
lipid modification GO:0030258 65 0.015
regulation of cellular response to stress GO:0080135 159 0.015
transition metal ion transport GO:0000041 38 0.015
heterocycle catabolic process GO:0046700 280 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
negative regulation of biomineral tissue development GO:0070168 11 0.015
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.015
response to glucocorticoid GO:0051384 20 0.015
regulation of striated muscle cell differentiation GO:0051153 81 0.015
kidney morphogenesis GO:0060993 83 0.015
cardiac muscle tissue development GO:0048738 130 0.015
morphogenesis of a polarized epithelium GO:0001738 37 0.015
regulation of erk1 and erk2 cascade GO:0070372 71 0.015
cellular response to lipid GO:0071396 145 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
positive regulation of lipid metabolic process GO:0045834 40 0.015
metanephric glomerular epithelial cell development GO:0072313 2 0.015
regulation of carbohydrate biosynthetic process GO:0043255 40 0.015
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.015
positive regulation of defense response GO:0031349 124 0.015
neuromuscular process GO:0050905 99 0.015
tissue migration GO:0090130 68 0.015
iron ion homeostasis GO:0055072 36 0.015
neutrophil chemotaxis GO:0030593 36 0.015
cellular response to dna damage stimulus GO:0006974 207 0.014
import into cell GO:0098657 8 0.014
peptide transport GO:0015833 133 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
leukocyte migration GO:0050900 124 0.014
negative regulation of leukocyte differentiation GO:1902106 51 0.014
regulation of fatty acid biosynthetic process GO:0042304 12 0.014
lipid oxidation GO:0034440 29 0.014
renal tubule development GO:0061326 87 0.014
neuron projection extension GO:1990138 64 0.014
nucleotide catabolic process GO:0009166 217 0.014
negative regulation of response to oxidative stress GO:1902883 10 0.014
cellular chemical homeostasis GO:0055082 215 0.014
positive regulation of granulocyte chemotaxis GO:0071624 12 0.014
skeletal muscle organ development GO:0060538 163 0.014
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.014
acute inflammatory response GO:0002526 41 0.014
Human
neural tube formation GO:0001841 108 0.014
regulation of viral entry into host cell GO:0046596 12 0.014
axonogenesis GO:0007409 274 0.014
regionalization GO:0003002 337 0.013
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.013
regulation of protein localization GO:0032880 231 0.013
limb morphogenesis GO:0035108 149 0.013
cardiac chamber morphogenesis GO:0003206 93 0.013
positive regulation of camp dependent protein kinase activity GO:2000481 3 0.013
cellular biogenic amine metabolic process GO:0006576 28 0.013
hair cycle GO:0042633 90 0.013
astrocyte development GO:0014002 12 0.013
bmp signaling pathway GO:0030509 93 0.013
metanephric glomerular epithelial cell differentiation GO:0072312 2 0.013
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.013
regulation of phospholipase a2 activity GO:0032429 3 0.013
nucleobase containing small molecule metabolic process GO:0055086 352 0.013
interleukin 12 secretion GO:0072610 3 0.013

Serping1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
hemolytic anemia DOID:583 0 0.686
disease of anatomical entity DOID:7 0 0.686
Human
anemia DOID:2355 0 0.686
normocytic anemia DOID:720 0 0.686
hematopoietic system disease DOID:74 0 0.686
immune system disease DOID:2914 0 0.686
hemolytic uremic syndrome DOID:12554 0 0.686
nervous system disease DOID:863 0 0.110
disease of metabolism DOID:0014667 0 0.086
inherited metabolic disorder DOID:655 0 0.086
eye disease DOID:5614 0 0.053
retinal disease DOID:5679 0 0.053
sensory system disease DOID:0050155 0 0.053
retinal degeneration DOID:8466 0 0.053
eye and adnexa disease DOID:1492 0 0.053
lipid metabolism disorder DOID:3146 0 0.026
connective tissue disease DOID:65 0 0.024
musculoskeletal system disease DOID:17 0 0.024
bone disease DOID:0080001 0 0.022
bone development disease DOID:0080006 0 0.022
age related macular degeneration DOID:10871 0 0.017
degeneration of macula and posterior pole DOID:2007 0 0.017
macular degeneration DOID:4448 0 0.017
acquired metabolic disease DOID:0060158 0 0.016
osteochondrodysplasia DOID:2256 0 0.014