Mus musculus

50 known processes

Sf1

splicing factor 1

(Aliases: Zfp162,MZFM,WBP4,CW17R,BB094781)

Sf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
covalent chromatin modification GO:0016569 163 0.392
male gamete generation GO:0048232 285 0.233
spermatogenesis GO:0007283 284 0.230
chromatin modification GO:0016568 187 0.217
rna splicing GO:0008380 54 0.208
oocyte axis specification GO:0007309 2 0.201
rna processing GO:0006396 105 0.182
histone h3 acetylation GO:0043966 14 0.159
cell fate commitment GO:0045165 210 0.144
histone lysine methylation GO:0034968 50 0.135
mrna splicing via spliceosome GO:0000398 43 0.123
histone methylation GO:0016571 71 0.114
embryonic organ morphogenesis GO:0048562 276 0.090
histone modification GO:0016570 159 0.088
peptidyl lysine modification GO:0018205 77 0.087
protein methylation GO:0006479 81 0.085
regionalization GO:0003002 337 0.084
mrna processing GO:0006397 63 0.083
regulation of transcription during meiosis GO:0051037 1 0.081
chromatin organization GO:0006325 206 0.078
regulation of mrna metabolic process GO:1903311 43 0.077
histone h4 k12 acetylation GO:0043983 2 0.070
blastocyst development GO:0001824 80 0.069
macromolecule methylation GO:0043414 120 0.067
regulation of cellular response to stress GO:0080135 159 0.066
oocyte construction GO:0007308 2 0.065
mrna metabolic process GO:0016071 84 0.064
axonogenesis GO:0007409 274 0.064
regulation of mrna processing GO:0050684 41 0.063
wnt signaling pathway GO:0016055 188 0.063
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.062
histone h3 k4 methylation GO:0051568 23 0.062
stem cell differentiation GO:0048863 268 0.062
development of primary sexual characteristics GO:0045137 143 0.060
rna interference GO:0016246 2 0.058
stem cell development GO:0048864 219 0.057
peptidyl amino acid modification GO:0018193 336 0.057
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.055
rna splicing via transesterification reactions GO:0000375 43 0.053
nuclear division GO:0000280 158 0.051
Worm
intracellular mrna localization GO:0008298 4 0.051
pole plasm assembly GO:0007315 2 0.050
histone h4 k16 acetylation GO:0043984 3 0.047
germ cell development GO:0007281 185 0.047
Worm
posttranscriptional regulation of gene expression GO:0010608 155 0.047
protein alkylation GO:0008213 81 0.046
myeloid cell differentiation GO:0030099 233 0.046
leukocyte mediated immunity GO:0002443 174 0.046
internal protein amino acid acetylation GO:0006475 42 0.046
regulation of cell cycle GO:0051726 281 0.046
Worm
epithelial tube morphogenesis GO:0060562 303 0.045
somatic cell dna recombination GO:0016444 51 0.040
regulation of rna splicing GO:0043484 37 0.040
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.039
neural precursor cell proliferation GO:0061351 121 0.038
cellular response to dna damage stimulus GO:0006974 207 0.038
dna metabolic process GO:0006259 303 0.038
negative regulation of cellular protein metabolic process GO:0032269 247 0.037
dephosphorylation GO:0016311 129 0.037
histone acetylation GO:0016573 41 0.037
regulation of translation GO:0006417 71 0.037
lung development GO:0030324 164 0.036
regulation of mrna splicing via spliceosome GO:0048024 32 0.036
oogenesis GO:0048477 56 0.036
stem cell maintenance GO:0019827 130 0.036
cytoplasmic transport GO:0016482 234 0.035
gene silencing GO:0016458 38 0.035
internal peptidyl lysine acetylation GO:0018393 42 0.035
negative regulation of protein metabolic process GO:0051248 282 0.035
translation GO:0006412 93 0.034
blastocyst growth GO:0001832 23 0.033
regulation of wnt signaling pathway GO:0030111 123 0.033
histone h4 acetylation GO:0043967 10 0.033
nucleocytoplasmic transport GO:0006913 139 0.033
oocyte anterior posterior axis specification GO:0007314 2 0.033
meiotic cell cycle GO:0051321 122 0.033
Worm
muscle tissue development GO:0060537 308 0.033
gland development GO:0048732 330 0.033
response to organonitrogen compound GO:0010243 246 0.033
regulation of cellular component biogenesis GO:0044087 181 0.033
lymphocyte mediated immunity GO:0002449 139 0.032
nucleoside catabolic process GO:0009164 206 0.032
embryonic skeletal system development GO:0048706 120 0.032
heterocycle catabolic process GO:0046700 280 0.032
maternal determination of anterior posterior axis embryo GO:0008358 2 0.032
respiratory tube development GO:0030323 167 0.031
cellular response to organonitrogen compound GO:0071417 145 0.031
meiotic nuclear division GO:0007126 115 0.031
Worm
respiratory system development GO:0060541 190 0.031
cell fate specification GO:0001708 72 0.031
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.031
mitotic cell cycle process GO:1903047 159 0.031
genitalia development GO:0048806 37 0.030
Worm
bone development GO:0060348 120 0.030
adaptive immune response GO:0002250 155 0.029
protein catabolic process GO:0030163 221 0.029
organelle fission GO:0048285 170 0.029
Worm
hormone secretion GO:0046879 128 0.029
methylation GO:0032259 134 0.029
positive regulation of nervous system development GO:0051962 221 0.028
positive regulation of dna templated transcription elongation GO:0032786 2 0.028
regulation of binding GO:0051098 111 0.028
rna localization GO:0006403 23 0.028
regulation of lymphocyte activation GO:0051249 240 0.027
regulation of establishment of protein localization GO:0070201 181 0.027
rhythmic process GO:0048511 174 0.027
protein acylation GO:0043543 64 0.027
regulation of membrane potential GO:0042391 192 0.027
intracellular protein transport GO:0006886 204 0.027
male meiosis i GO:0007141 16 0.027
chemotaxis GO:0006935 247 0.027
cellular macromolecule catabolic process GO:0044265 206 0.027
protein localization to nucleus GO:0034504 121 0.026
placenta development GO:0001890 140 0.026
lateral inhibition GO:0046331 1 0.026
peptidyl lysine acetylation GO:0018394 45 0.026
septum primum development GO:0003284 4 0.026
kidney development GO:0001822 213 0.026
stem cell fate specification GO:0048866 3 0.026
primary neural tube formation GO:0014020 95 0.026
modification dependent protein catabolic process GO:0019941 133 0.026
protein localization to organelle GO:0033365 185 0.026
epithelial cell development GO:0002064 159 0.026
synaptic transmission GO:0007268 329 0.025
regulation of cell activation GO:0050865 289 0.025
epithelial tube formation GO:0072175 130 0.025
t cell activation GO:0042110 289 0.025
neural tube development GO:0021915 160 0.025
single organism cell adhesion GO:0098602 156 0.025
gonad development GO:0008406 141 0.025
neuroblast differentiation GO:0014016 2 0.025
regulation of hormone levels GO:0010817 211 0.025
negative regulation of cell proliferation GO:0008285 296 0.025
nitrogen compound transport GO:0071705 271 0.025
negative regulation of molecular function GO:0044092 258 0.024
mesenchyme development GO:0060485 152 0.024
modification dependent macromolecule catabolic process GO:0043632 133 0.024
stem cell proliferation GO:0072089 117 0.024
immune effector process GO:0002252 321 0.024
regulation of cell cycle process GO:0010564 160 0.024
Worm
leukocyte differentiation GO:0002521 342 0.023
urogenital system development GO:0001655 261 0.023
circadian rhythm GO:0007623 114 0.023
cellular protein catabolic process GO:0044257 155 0.023
nuclear transport GO:0051169 139 0.023
forebrain development GO:0030900 302 0.023
peptidyl lysine methylation GO:0018022 29 0.023
response to organic cyclic compound GO:0014070 198 0.023
embryonic epithelial tube formation GO:0001838 130 0.023
apoptotic signaling pathway GO:0097190 306 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.022
response to peptide hormone GO:0043434 127 0.022
canonical wnt signaling pathway GO:0060070 130 0.022
regulation of chromatin modification GO:1903308 57 0.022
digestive system development GO:0055123 200 0.022
oocyte differentiation GO:0009994 35 0.022
regulation of inflammatory response GO:0050727 147 0.022
negative regulation of protein modification process GO:0031400 163 0.022
regulation of neuron death GO:1901214 134 0.022
sensory organ morphogenesis GO:0090596 242 0.021
digestive tract morphogenesis GO:0048546 147 0.021
cell adhesion GO:0007155 329 0.021
skeletal system development GO:0001501 356 0.021
microtubule based process GO:0007017 236 0.021
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.021
negative regulation of multi organism process GO:0043901 68 0.021
somatic diversification of immune receptors GO:0002200 53 0.021
regulation of histone methylation GO:0031060 30 0.021
regulation of neuron apoptotic process GO:0043523 122 0.021
muscle cell differentiation GO:0042692 261 0.021
carboxylic acid biosynthetic process GO:0046394 86 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
spermatid differentiation GO:0048515 115 0.020
alternative mrna splicing via spliceosome GO:0000380 12 0.020
positive regulation of protein modification process GO:0031401 299 0.020
cell maturation GO:0048469 127 0.020
nuclear import GO:0051170 95 0.020
lymphocyte differentiation GO:0030098 242 0.020
inner cell mass cell proliferation GO:0001833 15 0.020
morphogenesis of a branching structure GO:0001763 203 0.020
cell division GO:0051301 120 0.020
Worm
regulation of b cell mediated immunity GO:0002712 37 0.020
connective tissue development GO:0061448 179 0.020
blood vessel morphogenesis GO:0048514 285 0.020
body morphogenesis GO:0010171 45 0.020
Worm
positive regulation of lymphocyte activation GO:0051251 140 0.019
cell junction organization GO:0034330 77 0.019
striated muscle tissue development GO:0014706 293 0.019
meiosis i GO:0007127 60 0.019
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
regulation of intracellular transport GO:0032386 159 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.019
digestive tract development GO:0048565 190 0.019
b cell activation GO:0042113 161 0.019
regulation of b cell activation GO:0050864 81 0.019
heart morphogenesis GO:0003007 178 0.019
spermatid development GO:0007286 108 0.019
aromatic compound catabolic process GO:0019439 286 0.019
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
neuron projection guidance GO:0097485 141 0.019
cardiac chamber development GO:0003205 108 0.019
neural tube formation GO:0001841 108 0.019
regulation of protein localization GO:0032880 231 0.018
transmission of nerve impulse GO:0019226 76 0.018
proteasomal protein catabolic process GO:0010498 98 0.018
cardiac muscle cell differentiation GO:0055007 69 0.018
regulation of ossification GO:0030278 112 0.018
cellular lipid metabolic process GO:0044255 323 0.018
lymphocyte activation involved in immune response GO:0002285 93 0.018
immunoglobulin production GO:0002377 73 0.018
posttranscriptional gene silencing GO:0016441 10 0.018
oligodendrocyte differentiation GO:0048709 53 0.018
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
ventricular septum development GO:0003281 42 0.018
t cell differentiation GO:0030217 174 0.018
cartilage development GO:0051216 140 0.017
single organismal cell cell adhesion GO:0016337 131 0.017
triglyceride biosynthetic process GO:0019432 17 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
posttranscriptional gene silencing by rna GO:0035194 10 0.017
embryonic genitalia morphogenesis GO:0030538 4 0.017
adult behavior GO:0030534 135 0.017
regulation of adaptive immune response GO:0002819 90 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
amide transport GO:0042886 138 0.017
developmental maturation GO:0021700 193 0.017
regulation of leukocyte mediated immunity GO:0002703 104 0.017
female gamete generation GO:0007292 74 0.017
membrane organization GO:0061024 245 0.017
inflammatory response GO:0006954 244 0.017
neuroblast fate commitment GO:0014017 1 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
establishment of organelle localization GO:0051656 122 0.016
gene silencing by rna GO:0031047 19 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
sensory perception GO:0007600 245 0.016
regulation of response to wounding GO:1903034 189 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
regulation of cellular protein catabolic process GO:1903362 61 0.016
locomotory behavior GO:0007626 195 0.016
regulation of chromosome organization GO:0033044 83 0.016
anatomical structure homeostasis GO:0060249 145 0.016
mrna transcription GO:0009299 4 0.016
dna recombination GO:0006310 92 0.016
cellularization GO:0007349 1 0.016
histone h3 k14 acetylation GO:0044154 3 0.016
gliogenesis GO:0042063 141 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
hindbrain development GO:0030902 128 0.015
neuronal action potential GO:0019228 54 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
regulation of lymphocyte mediated immunity GO:0002706 84 0.015
cell type specific apoptotic process GO:0097285 268 0.015
regulation of transferase activity GO:0051338 263 0.015
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.015
nucleobase containing compound transport GO:0015931 27 0.015
regulation of stem cell proliferation GO:0072091 78 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
regulation of system process GO:0044057 200 0.015
organic acid biosynthetic process GO:0016053 86 0.015
cellular amino acid metabolic process GO:0006520 103 0.015
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.015
tube formation GO:0035148 140 0.015
regulation of multi organism process GO:0043900 111 0.015
negative regulation of immune system process GO:0002683 209 0.015
negative regulation of cell development GO:0010721 169 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.015
gastrulation GO:0007369 116 0.015
mapk cascade GO:0000165 281 0.015
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.015
regulation of secretion by cell GO:1903530 249 0.015
leukocyte activation involved in immune response GO:0002366 126 0.014
cellular protein complex assembly GO:0043623 116 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
regulation of stem cell maintenance GO:2000036 17 0.014
regulation of chromatin organization GO:1902275 57 0.014
response to acid chemical GO:0001101 111 0.014
chromatin remodeling GO:0006338 32 0.014
receptor mediated endocytosis GO:0006898 51 0.014
Worm
regulation of immunoglobulin mediated immune response GO:0002889 37 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
cardiocyte differentiation GO:0035051 87 0.014
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 1 0.014
compound eye development GO:0048749 1 0.014
regulation of nucleocytoplasmic transport GO:0046822 73 0.014
regulation of hormone secretion GO:0046883 88 0.014
nuclear export GO:0051168 34 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
response to growth factor GO:0070848 198 0.014
negative regulation of cell cycle process GO:0010948 69 0.014
mitotic cell cycle GO:0000278 195 0.014
angiogenesis GO:0001525 201 0.014
hepaticobiliary system development GO:0061008 67 0.014
liver development GO:0001889 66 0.014
regulation of proteasomal protein catabolic process GO:0061136 46 0.014
immunoglobulin mediated immune response GO:0016064 69 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
regulation of histone h3 k4 methylation GO:0051569 12 0.014
regulation of stem cell differentiation GO:2000736 50 0.014
peptide hormone secretion GO:0030072 109 0.013
regulation of mapk cascade GO:0043408 248 0.013
nucleic acid transport GO:0050657 18 0.013
single fertilization GO:0007338 82 0.013
regulation of dna binding GO:0051101 39 0.013
multi multicellular organism process GO:0044706 109 0.013
meiotic cell cycle process GO:1903046 77 0.013
mitotic cytokinesis GO:0000281 4 0.013
glucose homeostasis GO:0042593 128 0.013
carbohydrate metabolic process GO:0005975 230 0.013
sensory perception of sound GO:0007605 97 0.013
cardiac cell fate specification GO:0060912 2 0.013
mesenchymal cell development GO:0014031 93 0.013
histone h4 k20 methylation GO:0034770 8 0.013
neutral lipid biosynthetic process GO:0046460 18 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
macromolecule catabolic process GO:0009057 281 0.013
regulation of immunoglobulin production GO:0002637 42 0.013
regulation of secretion GO:0051046 274 0.013
skeletal system morphogenesis GO:0048705 203 0.013
cell activation involved in immune response GO:0002263 126 0.013
anterior posterior axis specification embryo GO:0008595 9 0.013
peptide transport GO:0015833 133 0.013
interspecies interaction between organisms GO:0044419 83 0.013
circadian regulation of gene expression GO:0032922 48 0.013
acylglycerol biosynthetic process GO:0046463 18 0.013
negative regulation of translation GO:0017148 22 0.013
sensory system development GO:0048880 3 0.013
positive regulation of mrna processing GO:0050685 16 0.012
regulation of protein stability GO:0031647 52 0.012
negative regulation of nervous system development GO:0051961 156 0.012
regulation of cellular ketone metabolic process GO:0010565 66 0.012
cellular homeostasis GO:0019725 240 0.012
ossification GO:0001503 216 0.012
muscle system process GO:0003012 141 0.012
response to radiation GO:0009314 165 0.012
glial cell differentiation GO:0010001 131 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
regulation of protein complex assembly GO:0043254 83 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
regulation of hippo signaling GO:0035330 1 0.012
fertilization GO:0009566 127 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
positive regulation of growth GO:0045927 104 0.012
regulation of canonical wnt signaling pathway GO:0060828 82 0.012
regulation of map kinase activity GO:0043405 120 0.012
nucleotide catabolic process GO:0009166 217 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
positive regulation of transcription via serum response element binding GO:0010735 1 0.012
blastocyst formation GO:0001825 33 0.011
lipid biosynthetic process GO:0008610 179 0.011
regulation of triglyceride biosynthetic process GO:0010866 10 0.011
response to oxidative stress GO:0006979 123 0.011
response to insulin GO:0032868 100 0.011
cardiac muscle tissue development GO:0048738 130 0.011
spleen development GO:0048536 39 0.011
establishment of synaptic vesicle localization GO:0097480 57 0.011
isotype switching GO:0045190 36 0.011
neuron apoptotic process GO:0051402 142 0.011
skeletal muscle organ development GO:0060538 163 0.011
action potential GO:0001508 78 0.011
heterochromatin assembly GO:0031507 2 0.011
multi organism behavior GO:0051705 62 0.011
renal system development GO:0072001 225 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.011
b cell activation involved in immune response GO:0002312 50 0.011
camera type eye development GO:0043010 266 0.011
Zebrafish
multicellular organismal signaling GO:0035637 91 0.011
axon guidance GO:0007411 141 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
mesoderm development GO:0007498 100 0.011
skin development GO:0043588 220 0.011
embryonic placenta development GO:0001892 98 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
positive regulation of wnt signaling pathway GO:0030177 45 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
regulation of rna export from nucleus GO:0046831 4 0.011
positive regulation of cell development GO:0010720 237 0.011
regulation of peptide secretion GO:0002791 77 0.011
actin filament organization GO:0007015 113 0.011
blood circulation GO:0008015 195 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 8 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
small molecule biosynthetic process GO:0044283 132 0.011
nucleotide metabolic process GO:0009117 332 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
male meiosis GO:0007140 37 0.011
double strand break repair GO:0006302 48 0.011
regulation of neuron projection development GO:0010975 169 0.011
erythrocyte differentiation GO:0030218 88 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
positive regulation of cellular amine metabolic process GO:0033240 5 0.011
atrial septum primum morphogenesis GO:0003289 3 0.010
branching morphogenesis of an epithelial tube GO:0048754 159 0.010
glycerolipid metabolic process GO:0046486 122 0.010
protein targeting GO:0006605 143 0.010
organelle localization GO:0051640 179 0.010
endocrine system development GO:0035270 98 0.010
pharynx development GO:0060465 1 0.010
endomembrane system organization GO:0010256 147 0.010
response to light stimulus GO:0009416 135 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
endocytosis GO:0006897 168 0.010
Worm
triglyceride metabolic process GO:0006641 51 0.010
tissue homeostasis GO:0001894 115 0.010
cell junction assembly GO:0034329 52 0.010
cellular response to oxidative stress GO:0034599 76 0.010
regulation of lipid biosynthetic process GO:0046890 54 0.010
acylglycerol metabolic process GO:0006639 55 0.010
regulation of protein kinase activity GO:0045859 232 0.010
negative regulation of protein maturation GO:1903318 79 0.010

Sf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.015
nervous system disease DOID:863 0 0.015
hematologic cancer DOID:2531 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
immune system cancer DOID:0060083 0 0.013
organ system cancer DOID:0050686 0 0.013
cancer DOID:162 0 0.013
disease of metabolism DOID:0014667 0 0.011