|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.997
|
|
|
|
keratinocyte proliferation
|
GO:0043616 |
21 |
0.860
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.802
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.743
|
Worm |
|
|
t cell activation
|
GO:0042110 |
289 |
0.714
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.703
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.672
|
|
|
|
keratinocyte development
|
GO:0003334 |
10 |
0.650
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.635
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.626
|
|
|
|
water homeostasis
|
GO:0030104 |
27 |
0.608
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.595
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.587
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.584
|
|
|
|
positive regulation of immature t cell proliferation
|
GO:0033091 |
4 |
0.543
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.542
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.526
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.504
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.494
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.493
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.482
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.479
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.475
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.461
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.431
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
3 |
0.404
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.401
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.388
|
Human |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.370
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.348
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.333
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.317
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.306
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.302
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.301
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.288
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.285
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
3 |
0.281
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.278
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
29 |
0.277
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.277
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.275
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.269
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.268
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.267
|
Fly |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.263
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.254
|
|
|
|
epidermal cell division
|
GO:0010481 |
3 |
0.251
|
|
|
|
intermediate filament organization
|
GO:0045109 |
15 |
0.245
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.243
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.242
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.240
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.237
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.237
|
|
|
|
female genitalia morphogenesis
|
GO:0048807 |
3 |
0.230
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.230
|
Human Yeast Mouse |
|
|
intermediate filament based process
|
GO:0045103 |
27 |
0.230
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.229
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.228
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
3 |
0.226
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.223
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.222
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.222
|
Fly |
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.221
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.219
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.212
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.212
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.204
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.201
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.199
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.198
|
Worm Fly |
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.195
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
33 |
0.191
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.188
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.188
|
|
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
26 |
0.185
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.185
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.184
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.184
|
Fly |
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.183
|
|
|
|
hepatocyte apoptotic process
|
GO:0097284 |
11 |
0.183
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.183
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.183
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.181
|
Yeast |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.179
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.176
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.174
|
|
|
|
satellite cell activation involved in skeletal muscle regeneration
|
GO:0014901 |
3 |
0.174
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.172
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.172
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.172
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.170
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.170
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.169
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.168
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.166
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.165
|
Human |
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.163
|
|
|
|
regulation of keratinocyte differentiation
|
GO:0045616 |
11 |
0.162
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.162
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.157
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.155
|
Fly |
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.148
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.148
|
|
|
|
tissue regeneration
|
GO:0042246 |
22 |
0.147
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.144
|
|
|
|
skin morphogenesis
|
GO:0043589 |
38 |
0.143
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.142
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.140
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.139
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
25 |
0.139
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.137
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.137
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.137
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.135
|
Yeast |
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
3 |
0.135
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.135
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.134
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.133
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.133
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.132
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.131
|
Fly |
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.130
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.129
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.128
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.127
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.127
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
4 |
0.127
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.125
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.125
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
3 |
0.124
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.123
|
|
|
|
cellular response to x ray
|
GO:0071481 |
2 |
0.122
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.122
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.121
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
3 |
0.121
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.120
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.119
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.119
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.118
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.118
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.117
|
Worm |
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.115
|
|
|
|
positive regulation of epidermal cell differentiation
|
GO:0045606 |
6 |
0.115
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.114
|
|
|
|
myoblast differentiation involved in skeletal muscle regeneration
|
GO:0014835 |
3 |
0.113
|
|
|
|
regulation of hippo signaling
|
GO:0035330 |
1 |
0.113
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.113
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.112
|
Human |
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.112
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.111
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.111
|
Yeast |
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.111
|
|
|
|
keratinization
|
GO:0031424 |
9 |
0.110
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.110
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.110
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
24 |
0.109
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.109
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.107
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.107
|
Human |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.107
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.106
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.106
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.105
|
Human |
|
|
muscle cell development
|
GO:0055001 |
133 |
0.105
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.105
|
Mouse |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.105
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.104
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.104
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.104
|
Yeast |
|
|
germ cell development
|
GO:0007281 |
185 |
0.104
|
Fly |
|
|
histone modification
|
GO:0016570 |
159 |
0.104
|
|
|
|
multicellular organismal water homeostasis
|
GO:0050891 |
23 |
0.103
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.103
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
23 |
0.102
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.101
|
Yeast |
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.101
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.100
|
Worm |
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.100
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.100
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.099
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.099
|
|
|
|
protein deacetylation
|
GO:0006476 |
32 |
0.098
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.098
|
|
|
|
negative regulation of keratinocyte differentiation
|
GO:0045617 |
4 |
0.098
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.097
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.097
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.096
|
|
|
|
renal vesicle induction
|
GO:0072034 |
3 |
0.096
|
|
|
|
establishment of skin barrier
|
GO:0061436 |
14 |
0.096
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.095
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.095
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.094
|
Fly |
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
21 |
0.093
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.093
|
Yeast |
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.093
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.093
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.093
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.093
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.092
|
|
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
3 |
0.092
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.092
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.092
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.092
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.092
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.091
|
|
|
|
response to interleukin 12
|
GO:0070671 |
2 |
0.091
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.089
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.088
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.088
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.087
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.087
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.087
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.085
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.085
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.084
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.084
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.083
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.083
|
Yeast Mouse |
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.082
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.082
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.082
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
8 |
0.082
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
3 |
0.082
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.082
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.082
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.080
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.080
|
|
|
|
positive regulation of epidermis development
|
GO:0045684 |
13 |
0.080
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.079
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.078
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.078
|
Worm |
|
|
cell killing
|
GO:0001906 |
67 |
0.078
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.077
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.077
|
Worm Fly |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.077
|
Human Yeast Mouse |
|
|
regulation of epidermis development
|
GO:0045682 |
33 |
0.076
|
|
|
|
positive regulation of keratinocyte proliferation
|
GO:0010838 |
4 |
0.076
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.076
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.075
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.074
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.074
|
Fly |
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
5 |
0.074
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.074
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.074
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.073
|
|
|
|
microglia development
|
GO:0014005 |
2 |
0.073
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
3 |
0.073
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.072
|
Worm Fly |
|
|
cell differentiation involved in embryonic placenta development
|
GO:0060706 |
26 |
0.072
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.071
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.071
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.071
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.071
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.071
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.071
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.070
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.070
|
|
|
|
positive regulation of cardiac muscle cell apoptotic process
|
GO:0010666 |
3 |
0.069
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.069
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.068
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.068
|
|
|
|
regeneration
|
GO:0031099 |
38 |
0.068
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.067
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.067
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.067
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.067
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.066
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.065
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.065
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.065
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.065
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.065
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.064
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.064
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.064
|
Worm |
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.064
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.064
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.063
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.063
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.063
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.062
|
Yeast Worm |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.062
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.062
|
|
|
|
cellular response to calcium ion
|
GO:0071277 |
14 |
0.062
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.062
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.062
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.062
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.062
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.061
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.061
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.061
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.061
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.061
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.060
|
Yeast |
|
|
response to dsrna
|
GO:0043331 |
30 |
0.060
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.060
|
|
|
|
positive regulation of striated muscle cell apoptotic process
|
GO:0010663 |
3 |
0.060
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.060
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.060
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.059
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.059
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.059
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.059
|
|
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
3 |
0.059
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.059
|
|
|
|
closure of optic fissure
|
GO:0061386 |
2 |
0.058
|
|
|
|
desmosome assembly
|
GO:0002159 |
1 |
0.058
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.058
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.058
|
Human |
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.058
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.057
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.057
|
Yeast |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.057
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.057
|
|
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
26 |
0.057
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.057
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator
|
GO:0006978 |
2 |
0.056
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.056
|
|
|
|
positive regulation of fibroblast growth factor receptor signaling pathway
|
GO:0045743 |
3 |
0.056
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
8 |
0.056
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.056
|
Yeast Fly |
|
|
negative regulation of phosphatidylinositol 3 kinase activity
|
GO:0043553 |
1 |
0.055
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.055
|
|
|
|
cellular response to gamma radiation
|
GO:0071480 |
4 |
0.055
|
|
|
|
regulation of protein deacetylation
|
GO:0090311 |
17 |
0.055
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.055
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.055
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.054
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.054
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.053
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.053
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.053
|
Human Yeast |
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.053
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.052
|
|
|
|
regulation of satellite cell activation involved in skeletal muscle regeneration
|
GO:0014717 |
3 |
0.052
|
|
|
|
embryonic neurocranium morphogenesis
|
GO:0048702 |
3 |
0.052
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.052
|
Yeast Worm |
|
|
mitochondrion degradation
|
GO:0000422 |
3 |
0.052
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.052
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.051
|
Fly |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.051
|
Human Yeast |
|
|
regulation of axon extension
|
GO:0030516 |
43 |
0.051
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.051
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.051
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.050
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.050
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
10 |
0.050
|
|
|
|
negative regulation of keratinocyte proliferation
|
GO:0010839 |
7 |
0.050
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.050
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.050
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
9 |
0.050
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.049
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.049
|
|
|
|
g0 to g1 transition
|
GO:0045023 |
3 |
0.049
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.049
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.049
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.049
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.048
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.048
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.047
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.047
|
Yeast |
|
|
negative regulation of stem cell proliferation
|
GO:2000647 |
12 |
0.047
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.047
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.047
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
28 |
0.047
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.047
|
|
|
|
endocrine process
|
GO:0050886 |
39 |
0.047
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.046
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.046
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.046
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
31 |
0.045
|
Yeast |
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.045
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.045
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.045
|
Human |
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.045
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.045
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.044
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.044
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.044
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.044
|
Mouse |
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
34 |
0.044
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.044
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.044
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.044
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.044
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.044
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.043
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.043
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.043
|
|
|
|
primary prostatic bud elongation
|
GO:0060516 |
2 |
0.042
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.042
|
Yeast Worm |
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.042
|
Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.042
|
Yeast Worm |
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.042
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.042
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:1902255 |
2 |
0.042
|
|
|
|
regulation of dna replication
|
GO:0006275 |
17 |
0.042
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.042
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.042
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.042
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.042
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.042
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.042
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.042
|
Yeast |
|
|
nuclear transport
|
GO:0051169 |
139 |
0.041
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
35 |
0.041
|
|
|
|
sensory system development
|
GO:0048880 |
3 |
0.041
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.041
|
|
|
|
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
|
GO:0061350 |
2 |
0.040
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.040
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.040
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.040
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.040
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.040
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.040
|
|
|
|
ureter morphogenesis
|
GO:0072197 |
4 |
0.040
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.039
|
Human |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.039
|
|
|
|
regulation of dna binding
|
GO:0051101 |
39 |
0.039
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.039
|
|
|
|
genitalia development
|
GO:0048806 |
37 |
0.038
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.038
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.038
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.038
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.038
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.038
|
|
|
|
regulation of systemic arterial blood pressure mediated by a chemical signal
|
GO:0003044 |
33 |
0.038
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.038
|
Yeast |
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.038
|
|
|
|
germ line stem cell division
|
GO:0042078 |
2 |
0.038
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.038
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.038
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.038
|
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
11 |
0.038
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
1 |
0.038
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.037
|
Human |
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.037
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
27 |
0.037
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.037
|
Yeast |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.037
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.037
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
35 |
0.036
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.036
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.036
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.036
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.036
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.036
|
|
|
|
chondrocyte hypertrophy
|
GO:0003415 |
4 |
0.036
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.036
|
Worm Fly |
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.036
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.036
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.036
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.036
|
|
|
|
positive regulation of lens epithelial cell proliferation
|
GO:2001111 |
1 |
0.036
|
|
|
|
rrna transcription
|
GO:0009303 |
9 |
0.036
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.036
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.035
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.035
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.035
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.035
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.035
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.035
|
|
|
|
desmosome organization
|
GO:0002934 |
5 |
0.035
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.035
|
|
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
37 |
0.035
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.035
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.035
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.035
|
|
|
|
mitochondrial dna repair
|
GO:0043504 |
3 |
0.035
|
|
|
|
regulation of cd8 positive alpha beta cytotoxic t cell extravasation
|
GO:2000452 |
2 |
0.035
|
|
|
|
renal system process
|
GO:0003014 |
48 |
0.035
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.034
|
|
|
|
cloacal septation
|
GO:0060197 |
2 |
0.034
|
|
|
|
negative regulation of cellular senescence
|
GO:2000773 |
3 |
0.034
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.034
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.034
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.034
|
|
|
|
detection of mechanical stimulus involved in equilibrioception
|
GO:0050973 |
2 |
0.034
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.034
|
|
|
|
intrahepatic bile duct development
|
GO:0035622 |
2 |
0.034
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.034
|
Yeast Worm Fly |
|
|
gliogenesis
|
GO:0042063 |
141 |
0.034
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.034
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.033
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.033
|
|
|
|
positive regulation of skeletal muscle tissue regeneration
|
GO:0043415 |
4 |
0.033
|
|
