|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.640
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.626
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.585
|
Mouse |
|
|
regionalization
|
GO:0003002 |
337 |
0.527
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.456
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.421
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.420
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.418
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.399
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.390
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.388
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.368
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.354
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.350
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.341
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.320
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.319
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.315
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.312
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.309
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.309
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.305
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.299
|
Mouse Fly |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.296
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.294
|
Mouse |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.288
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.281
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.277
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.277
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.276
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.273
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.271
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.267
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.264
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.263
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.255
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.254
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.254
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.251
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.251
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.245
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.243
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.242
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.238
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.235
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.233
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.227
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.226
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.217
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.213
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.213
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.212
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.211
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.211
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.209
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.205
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.205
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.202
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.201
|
|
|
|
definitive hemopoiesis
|
GO:0060216 |
20 |
0.196
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.194
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.193
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.193
|
Mouse Fly |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.192
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.192
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.192
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.191
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.189
|
Mouse Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.186
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.182
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.177
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.170
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.170
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.169
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.169
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.169
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.167
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.166
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.160
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.159
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.159
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.156
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.153
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.150
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.149
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.148
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.147
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.147
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.146
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.146
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.146
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.145
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.143
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.141
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.141
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.141
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.139
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.135
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.135
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.135
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.134
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.133
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.132
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.130
|
Mouse Fly |
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.130
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.128
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.126
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.126
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.122
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.120
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.120
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.120
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.119
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.118
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.117
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.117
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.117
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.116
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.114
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.113
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.112
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.112
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.111
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.111
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.111
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.110
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.110
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.110
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.109
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.109
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.109
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.108
|
Mouse |
|
|
germ cell development
|
GO:0007281 |
185 |
0.108
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.108
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.108
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.107
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.107
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.106
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.106
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.106
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.105
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.105
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.105
|
|
|
|
male gonad development
|
GO:0008584 |
88 |
0.105
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.104
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.103
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.103
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.103
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.103
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.101
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.101
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.100
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.100
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.099
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.097
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.097
|
Mouse Fly |
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.097
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.097
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.097
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.096
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.096
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.095
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.095
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.095
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.094
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.093
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.093
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.093
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.092
|
Mouse |
|
|
tube formation
|
GO:0035148 |
140 |
0.091
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.090
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.090
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.090
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.090
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.089
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.089
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.089
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.089
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.088
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.088
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.088
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.087
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.087
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.086
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.086
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.086
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.085
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.084
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.083
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.083
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.083
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.083
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.082
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.082
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.082
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.082
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.081
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.081
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.080
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.080
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.079
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.078
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.078
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.078
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.078
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.078
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.078
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.078
|
Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.077
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.077
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.076
|
Mouse Fly |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.076
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.075
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.075
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.075
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.074
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.074
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.074
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.074
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.072
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.072
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.071
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.071
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.071
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.070
|
|
|
|
glycosylation
|
GO:0070085 |
62 |
0.069
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.069
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.069
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.069
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.069
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.069
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.069
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.068
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.068
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.068
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.068
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.068
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.067
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.067
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.067
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.066
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.066
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.066
|
Mouse Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.066
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.066
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.066
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.066
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.066
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.066
|
Mouse |
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.066
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.065
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.065
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.065
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.064
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.063
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.063
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.063
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.063
|
Mouse |
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.063
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.063
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.062
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.062
|
Mouse |
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.062
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.061
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.061
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.061
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.060
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.060
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.060
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.060
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.060
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.059
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.059
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.059
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.059
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.059
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.059
|
|
|
|
cardiac septum development
|
GO:0003279 |
59 |
0.059
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.059
|
Mouse |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.059
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.059
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.058
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.058
|
Mouse |
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.058
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.058
|
Mouse |
|
|
muscle cell development
|
GO:0055001 |
133 |
0.058
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.058
|
|
|
|
protein glycosylation
|
GO:0006486 |
55 |
0.058
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.057
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.057
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.057
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.057
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.056
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.055
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.055
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
65 |
0.055
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.055
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.054
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.054
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.054
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.053
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.053
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.053
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.053
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.053
|
Mouse |
|
|
negative regulation of fat cell differentiation
|
GO:0045599 |
36 |
0.053
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.052
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.052
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.052
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.052
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.051
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.050
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.050
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.050
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.050
|
|
|
|
cerebellar granule cell precursor tangential migration
|
GO:0021935 |
1 |
0.050
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.050
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.050
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.050
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.049
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.049
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.049
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.049
|
|
|
|
lung cell differentiation
|
GO:0060479 |
30 |
0.049
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.049
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.048
|
|
|
|
mitral valve development
|
GO:0003174 |
4 |
0.048
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.047
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.047
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.047
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.047
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.047
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.047
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.047
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.047
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.046
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.046
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.046
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.046
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.046
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.046
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.046
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.046
|
Mouse |
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.046
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.045
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.045
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.045
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.045
|
Mouse |
|
|
placenta development
|
GO:0001890 |
140 |
0.045
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.045
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.045
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.044
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.044
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.044
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.044
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.044
|
Mouse |
|
|
cell division
|
GO:0051301 |
120 |
0.044
|
Mouse |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.044
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.044
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.044
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.044
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.044
|
Mouse |
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.043
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.043
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.043
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.043
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.043
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
47 |
0.043
|
|
|
|
response to fluid shear stress
|
GO:0034405 |
7 |
0.043
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.043
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.043
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.043
|
Fly |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.043
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.042
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.042
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.042
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.042
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.042
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.041
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.041
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.041
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.041
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
71 |
0.041
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.041
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.041
|
|
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.041
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.041
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.041
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.040
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.040
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.040
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.039
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.039
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.039
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.039
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.039
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.039
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.039
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.039
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.039
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.039
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.039
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.039
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.038
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.038
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.038
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.038
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.038
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.038
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.038
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.038
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.038
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.037
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.037
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.037
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.037
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.037
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.037
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.037
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.036
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.036
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.036
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.036
|
Mouse |
|
|
coagulation
|
GO:0050817 |
78 |
0.036
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.036
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.036
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.035
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.035
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.035
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.035
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.035
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.035
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.034
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.034
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.034
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.034
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.034
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.034
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.034
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.034
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.033
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.033
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.033
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.033
|
|
|
|
mesoderm formation
|
GO:0001707 |
62 |
0.033
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.033
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.033
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.033
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.033
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.033
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.033
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.032
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
55 |
0.032
|
|
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.032
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.032
|
Mouse Fly |
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.032
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.032
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.032
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.031
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.031
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.031
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.031
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.031
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
44 |
0.031
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.031
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.030
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.030
|
|
|
|
cellular response to epidermal growth factor stimulus
|
GO:0071364 |
4 |
0.030
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.030
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.030
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.030
|
|
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.030
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.030
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.030
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.030
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.030
|
|
|
|
memory
|
GO:0007613 |
58 |
0.030
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.030
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.030
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.030
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.030
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.030
|
|
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.030
|
|
|
|
negative regulation of osteoblast proliferation
|
GO:0033689 |
4 |
0.029
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.029
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.029
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.029
|
Mouse |
|
|
polysaccharide biosynthetic process
|
GO:0000271 |
20 |
0.029
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.029
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.029
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.029
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.029
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.029
|
|
