Mus musculus

256 known processes

Shox2

short stature homeobox 2

(Aliases: 6330543G17Rik,Og12x,OG12,SHOT,Prx3)

Shox2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal system development GO:0001501 356 0.889
neural tube development GO:0021915 160 0.812
embryonic skeletal system development GO:0048706 120 0.809
muscle tissue development GO:0060537 308 0.807
embryonic organ morphogenesis GO:0048562 276 0.794
skeletal system morphogenesis GO:0048705 203 0.767
skeletal muscle organ development GO:0060538 163 0.748
striated muscle tissue development GO:0014706 293 0.730
connective tissue development GO:0061448 179 0.723
neural tube formation GO:0001841 108 0.675
appendage morphogenesis GO:0035107 149 0.670
forebrain development GO:0030900 302 0.661
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.639
skeletal muscle cell differentiation GO:0035914 66 0.623
tube closure GO:0060606 91 0.619
stem cell differentiation GO:0048863 268 0.609
cerebellum development GO:0021549 77 0.603
embryonic appendage morphogenesis GO:0035113 126 0.594
hindbrain development GO:0030902 128 0.586
cartilage development GO:0051216 140 0.575
primary neural tube formation GO:0014020 95 0.571
neural tube closure GO:0001843 90 0.551
spinal cord development GO:0021510 81 0.537
tube formation GO:0035148 140 0.537
muscle cell differentiation GO:0042692 261 0.523
embryonic epithelial tube formation GO:0001838 130 0.522
central nervous system neuron differentiation GO:0021953 162 0.521
embryonic skeletal system morphogenesis GO:0048704 91 0.516
bone development GO:0060348 120 0.492
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.481
epithelial tube morphogenesis GO:0060562 303 0.479
regulation of cell projection organization GO:0031344 206 0.470
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.464
regionalization GO:0003002 337 0.453
myeloid cell homeostasis GO:0002262 114 0.439
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.437
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.435
bmp signaling pathway GO:0030509 93 0.432
endocrine system development GO:0035270 98 0.409
regulation of wnt signaling pathway GO:0030111 123 0.409
regulation of myeloid cell differentiation GO:0045637 96 0.409
myeloid cell differentiation GO:0030099 233 0.399
regulation of neuron projection development GO:0010975 169 0.398
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.393
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.389
mesoderm development GO:0007498 100 0.381
morphogenesis of embryonic epithelium GO:0016331 159 0.369
regulation of cellular ketone metabolic process GO:0010565 66 0.363
neuron migration GO:0001764 122 0.354
regulation of organ morphogenesis GO:2000027 144 0.352
axon guidance GO:0007411 141 0.347
epithelial tube formation GO:0072175 130 0.346
gastrulation GO:0007369 116 0.345
positive regulation of cell development GO:0010720 237 0.344
cardiac chamber development GO:0003205 108 0.344
blood vessel morphogenesis GO:0048514 285 0.339
appendage development GO:0048736 166 0.337
cellular response to growth factor stimulus GO:0071363 197 0.335
heart morphogenesis GO:0003007 178 0.330
regulation of embryonic development GO:0045995 71 0.327
muscle cell development GO:0055001 133 0.326
axonogenesis GO:0007409 274 0.324
auditory receptor cell fate determination GO:0042668 3 0.324
digestive tract development GO:0048565 190 0.322
gland development GO:0048732 330 0.322
palate development GO:0060021 76 0.319
somitogenesis GO:0001756 69 0.319
regulation of mast cell differentiation GO:0060375 3 0.318
embryonic placenta development GO:0001892 98 0.312
mesenchyme development GO:0060485 152 0.305
developmental maturation GO:0021700 193 0.299
limb development GO:0060173 166 0.299
striated muscle cell development GO:0055002 125 0.298
aortic valve morphogenesis GO:0003180 4 0.294
regulation of cellular amino acid metabolic process GO:0006521 5 0.294
erythrocyte differentiation GO:0030218 88 0.291
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.290
stem cell development GO:0048864 219 0.290
wnt signaling pathway GO:0016055 188 0.289
chemotaxis GO:0006935 247 0.288
positive regulation of stem cell proliferation GO:2000648 59 0.288
cellular amino acid metabolic process GO:0006520 103 0.287
peptidyl amino acid modification GO:0018193 336 0.286
tendon formation GO:0035992 4 0.282
cell differentiation in spinal cord GO:0021515 53 0.282
cell fate specification GO:0001708 72 0.280
respiratory system development GO:0060541 190 0.277
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.275
regulation of muscle tissue development GO:1901861 97 0.275
organ growth GO:0035265 117 0.272
regulation of cell motility GO:2000145 236 0.271
spinal cord motor neuron differentiation GO:0021522 35 0.271
leukocyte differentiation GO:0002521 342 0.269
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.269
cell type specific apoptotic process GO:0097285 268 0.268
lung development GO:0030324 164 0.265
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.264
stem cell proliferation GO:0072089 117 0.260
cellular amine metabolic process GO:0044106 44 0.259
embryonic digit morphogenesis GO:0042733 56 0.259
pallium development GO:0021543 120 0.254
immune effector process GO:0002252 321 0.252
head morphogenesis GO:0060323 34 0.251
regulation of stem cell proliferation GO:0072091 78 0.251
cell fate commitment GO:0045165 210 0.250
positive regulation of epithelial cell proliferation GO:0050679 68 0.250
limb morphogenesis GO:0035108 149 0.248
cellular ketone metabolic process GO:0042180 84 0.246
hemangioblast cell differentiation GO:0060217 1 0.245
ossification GO:0001503 216 0.244
neuron projection guidance GO:0097485 141 0.241
cardiac chamber morphogenesis GO:0003206 93 0.241
pancreatic pp cell fate commitment GO:0003329 2 0.241
formation of primary germ layer GO:0001704 77 0.241
placenta development GO:0001890 140 0.241
digestive tract morphogenesis GO:0048546 147 0.238
camera type eye development GO:0043010 266 0.235
cardiac muscle tissue development GO:0048738 130 0.234
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.234
dorsal spinal cord development GO:0021516 20 0.230
regulation of cellular amine metabolic process GO:0033238 20 0.230
metencephalon development GO:0022037 89 0.230
cell adhesion GO:0007155 329 0.229
olfactory bulb development GO:0021772 30 0.227
cardiac septum morphogenesis GO:0060411 46 0.225
limbic system development GO:0021761 72 0.225
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.225
positive regulation of programmed cell death GO:0043068 218 0.221
astrocyte fate commitment GO:0060018 4 0.221
heart formation GO:0060914 16 0.221
cardiocyte differentiation GO:0035051 87 0.220
response to growth factor GO:0070848 198 0.220
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.219
regulation of neuron apoptotic process GO:0043523 122 0.219
anatomical structure homeostasis GO:0060249 145 0.219
muscle tissue morphogenesis GO:0060415 53 0.217
diencephalon development GO:0021536 63 0.217
positive regulation of apoptotic process GO:0043065 217 0.215
cartilage morphogenesis GO:0060536 11 0.211
negative regulation of wnt signaling pathway GO:0030178 73 0.209
negative regulation of cell development GO:0010721 169 0.209
peripheral nervous system neuron axonogenesis GO:0048936 3 0.207
trachea cartilage morphogenesis GO:0060535 4 0.206
cerebral cortex development GO:0021987 86 0.206
actin cytoskeleton organization GO:0030036 220 0.206
ear morphogenesis GO:0042471 118 0.205
epithelial cell proliferation GO:0050673 174 0.203
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.202
auditory receptor cell fate specification GO:0042667 1 0.200
mesenchymal cell proliferation GO:0010463 44 0.196
regulation of neuron differentiation GO:0045664 281 0.192
mitral valve morphogenesis GO:0003183 4 0.191
visceral motor neuron differentiation GO:0021524 3 0.190
negative regulation of cell proliferation GO:0008285 296 0.190
regulation of myotube differentiation GO:0010830 62 0.189
pituitary gland development GO:0021983 38 0.188
regulation of organelle organization GO:0033043 289 0.187
epidermis development GO:0008544 187 0.186
midbrain development GO:0030901 35 0.186
neural crest cell migration GO:0001755 32 0.186
canonical wnt signaling pathway GO:0060070 130 0.186
hippocampus development GO:0021766 52 0.185
telencephalon development GO:0021537 186 0.184
endocardial cushion morphogenesis GO:0003203 18 0.184
chondrocyte differentiation GO:0002062 72 0.182
renal system development GO:0072001 225 0.182
tongue development GO:0043586 18 0.181
cytokine production GO:0001816 319 0.181
segmentation GO:0035282 93 0.180
forebrain regionalization GO:0021871 25 0.179
cardiac muscle cell differentiation GO:0055007 69 0.177
myoblast differentiation GO:0045445 52 0.176
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.176
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.174
locomotory behavior GO:0007626 195 0.174
cerebral cortex neuron differentiation GO:0021895 19 0.173
negative regulation of epithelial cell proliferation GO:0050680 64 0.169
positive regulation of cell adhesion GO:0045785 80 0.169
apoptotic process involved in morphogenesis GO:0060561 25 0.169
positive regulation of protein modification process GO:0031401 299 0.168
neural crest cell differentiation GO:0014033 54 0.167
positive regulation of protein phosphorylation GO:0001934 242 0.167
morphogenesis of a branching epithelium GO:0061138 193 0.167
regulation of epithelial cell proliferation GO:0050678 141 0.166
mesenchymal cell differentiation GO:0048762 107 0.164
tendon cell differentiation GO:0035990 4 0.164
positive regulation of nervous system development GO:0051962 221 0.164
innate immune response GO:0045087 157 0.163
determination of left right symmetry GO:0007368 80 0.162
positive regulation of cellular amine metabolic process GO:0033240 5 0.162
somite development GO:0061053 81 0.160
forebrain neuron fate commitment GO:0021877 13 0.160
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.160
negative regulation of nervous system development GO:0051961 156 0.159
negative regulation of neuron death GO:1901215 98 0.158
pancreatic a cell fate commitment GO:0003326 2 0.156
mesoderm morphogenesis GO:0048332 64 0.156
regulation of neuron death GO:1901214 134 0.155
response to organic cyclic compound GO:0014070 198 0.154
digestive system development GO:0055123 200 0.154
gonad development GO:0008406 141 0.154
hair cycle GO:0042633 90 0.153
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.152
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.152
negative regulation of growth GO:0045926 99 0.150
forebrain generation of neurons GO:0021872 63 0.149
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.148
mitral valve development GO:0003174 4 0.148
sensory organ morphogenesis GO:0090596 242 0.148
female gonad development GO:0008585 71 0.148
positive regulation of skeletal muscle fiber development GO:0048743 3 0.147
cerebellar cortex development GO:0021695 48 0.147
negative regulation of cellular amine metabolic process GO:0033239 1 0.147
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.147
extracellular structure organization GO:0043062 148 0.146
cardiac ventricle morphogenesis GO:0003208 50 0.146
endodermal cell fate specification GO:0001714 4 0.146
oxidation reduction process GO:0055114 342 0.145
lateral line system development GO:0048925 1 0.145
epithelial to mesenchymal transition GO:0001837 47 0.144
negative regulation of synapse maturation GO:2000297 2 0.143
myeloid leukocyte differentiation GO:0002573 119 0.143
forebrain neuron differentiation GO:0021879 52 0.143
regulation of ossification GO:0030278 112 0.142
glucose homeostasis GO:0042593 128 0.141
regulation of canonical wnt signaling pathway GO:0060828 82 0.140
ameboidal type cell migration GO:0001667 128 0.140
cardiac epithelial to mesenchymal transition GO:0060317 18 0.140
cell differentiation in hindbrain GO:0021533 24 0.139
transdifferentiation GO:0060290 1 0.139
mesenchymal cell development GO:0014031 93 0.138
bronchiole development GO:0060435 3 0.136
embryonic limb morphogenesis GO:0030326 126 0.136
ear development GO:0043583 200 0.136
face morphogenesis GO:0060325 29 0.136
cardiac muscle tissue morphogenesis GO:0055008 44 0.135
axis elongation involved in somitogenesis GO:0090245 4 0.135
positive regulation of mapk cascade GO:0043410 170 0.134
cell proliferation involved in heart valve development GO:2000793 2 0.134
embryonic heart tube formation GO:0003144 1 0.134
homeostasis of number of cells GO:0048872 210 0.133
regulation of lymphocyte activation GO:0051249 240 0.132
regulation of cellular catabolic process GO:0031329 242 0.132
synaptic transmission GO:0007268 329 0.131
regulation of organ formation GO:0003156 34 0.130
negative regulation of cell cycle GO:0045786 123 0.129
regulation of homeostatic process GO:0032844 182 0.129
rhythmic process GO:0048511 174 0.129
positive regulation of neuron differentiation GO:0045666 141 0.129
cardiac ventricle development GO:0003231 83 0.128
determination of heart left right asymmetry GO:0061371 48 0.128
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.126
development of primary sexual characteristics GO:0045137 143 0.126
cell proliferation in hindbrain GO:0021534 10 0.125
cell maturation GO:0048469 127 0.125
myotube differentiation GO:0014902 105 0.124
neuron projection extension GO:1990138 64 0.124
urogenital system development GO:0001655 261 0.124
tissue remodeling GO:0048771 102 0.124
visceral serous pericardium development GO:0061032 2 0.123
motor neuron migration GO:0097475 4 0.122
odontogenesis GO:0042476 78 0.122
positive regulation of cell death GO:0010942 224 0.121
regulation of auditory receptor cell differentiation GO:0045607 4 0.121
glial cell development GO:0021782 54 0.120
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.120
neuromuscular process GO:0050905 99 0.119
dorsal ventral axon guidance GO:0033563 3 0.119
regulation of erythrocyte differentiation GO:0045646 23 0.119
regulation of bmp signaling pathway GO:0030510 60 0.118
embryonic hindlimb morphogenesis GO:0035116 32 0.118
heart valve morphogenesis GO:0003179 21 0.117
negative regulation of neuron projection development GO:0010977 50 0.117
pericardium development GO:0060039 16 0.116
angiogenesis GO:0001525 201 0.116
b cell activation GO:0042113 161 0.116
sensory system development GO:0048880 3 0.116
cell differentiation involved in embryonic placenta development GO:0060706 26 0.116
morphogenesis of a polarized epithelium GO:0001738 37 0.115
body morphogenesis GO:0010171 45 0.115
pancreatic pp cell differentiation GO:0003312 2 0.115
developmental growth involved in morphogenesis GO:0060560 138 0.113
mammary gland epithelium development GO:0061180 65 0.113
regulation of mapk cascade GO:0043408 248 0.113
negative regulation of cellular component organization GO:0051129 194 0.112
spinal cord motor neuron cell fate specification GO:0021520 13 0.112
nerve development GO:0021675 67 0.112
glial cell differentiation GO:0010001 131 0.112
neuroblast proliferation GO:0007405 49 0.111
atrioventricular valve morphogenesis GO:0003181 13 0.111
extracellular matrix organization GO:0030198 147 0.111
skin development GO:0043588 220 0.111
spleen development GO:0048536 39 0.110
cellular response to calcium ion GO:0071277 14 0.110
embryonic heart tube development GO:0035050 65 0.110
cardiac right ventricle formation GO:0003219 3 0.110
lymphocyte differentiation GO:0030098 242 0.109
histone acetylation GO:0016573 41 0.109
cellular response to external stimulus GO:0071496 88 0.109
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.109
branching morphogenesis of an epithelial tube GO:0048754 159 0.109
regulation of osteoblast differentiation GO:0045667 67 0.109
respiratory tube development GO:0030323 167 0.109
regulation of retina development in camera type eye GO:1902866 3 0.107
nephron tubule morphogenesis GO:0072078 68 0.106
inner ear morphogenesis GO:0042472 101 0.106
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.106
positive regulation of keratinocyte proliferation GO:0010838 4 0.105
epithelial cell morphogenesis GO:0003382 41 0.105
muscle fiber development GO:0048747 76 0.104
ventricular septum morphogenesis GO:0060412 27 0.104
adult locomotory behavior GO:0008344 91 0.104
neuron apoptotic process GO:0051402 142 0.104
multi multicellular organism process GO:0044706 109 0.103
deltoid tuberosity development GO:0035993 3 0.103
specification of organ identity GO:0010092 30 0.102
adult behavior GO:0030534 135 0.102
cerebellum morphogenesis GO:0021587 42 0.102
protein modification by small protein conjugation GO:0032446 187 0.102
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.102
nephron development GO:0072006 109 0.101
epithelial cell development GO:0002064 159 0.100
kidney epithelium development GO:0072073 121 0.100
olfactory lobe development GO:0021988 32 0.100
regulation of secretion by cell GO:1903530 249 0.100
cell growth GO:0016049 130 0.099
regulation of cell activation GO:0050865 289 0.099
regulation of cell cycle GO:0051726 281 0.098
sensory perception GO:0007600 245 0.098
regulation of cardiac muscle cell proliferation GO:0060043 23 0.098
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.098
dopaminergic neuron differentiation GO:0071542 14 0.098
regulation of binding GO:0051098 111 0.097
negative regulation of myeloid cell differentiation GO:0045638 38 0.097
muscle cell fate commitment GO:0042693 11 0.097
heart valve development GO:0003170 23 0.097
positive regulation of protein kinase activity GO:0045860 144 0.096
trophectodermal cell differentiation GO:0001829 21 0.096
mechanoreceptor differentiation GO:0042490 67 0.096
regulation of neural retina development GO:0061074 3 0.096
b cell differentiation GO:0030183 78 0.095
mesoderm formation GO:0001707 62 0.094
morphogenesis of a branching structure GO:0001763 203 0.094
fat cell differentiation GO:0045444 160 0.094
ureteric bud development GO:0001657 94 0.093
ras protein signal transduction GO:0007265 77 0.093
apoptotic signaling pathway GO:0097190 306 0.093
pharyngeal system development GO:0060037 17 0.093
negative regulation of cell projection organization GO:0031345 56 0.092
histone modification GO:0016570 159 0.092
regulation of mesenchymal cell proliferation GO:0010464 37 0.092
ventricular septum development GO:0003281 42 0.091
retina development in camera type eye GO:0060041 119 0.091
regulation of apoptotic signaling pathway GO:2001233 197 0.091
amine metabolic process GO:0009308 45 0.091
outflow tract morphogenesis GO:0003151 53 0.091
adaptive immune response GO:0002250 155 0.090
embryonic forelimb morphogenesis GO:0035115 32 0.090
neural precursor cell proliferation GO:0061351 121 0.090
heart valve formation GO:0003188 10 0.089
peptidyl tyrosine modification GO:0018212 145 0.089
positive regulation of skeletal muscle cell differentiation GO:2001016 4 0.089
mesonephros development GO:0001823 97 0.088
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.087
intracellular distribution of mitochondria GO:0048312 1 0.087
mapk cascade GO:0000165 281 0.087
forelimb morphogenesis GO:0035136 40 0.087
pancreas development GO:0031016 57 0.087
cellular response to extracellular stimulus GO:0031668 81 0.086
neural crest cell development GO:0014032 48 0.085
inner ear receptor cell differentiation GO:0060113 61 0.085
t cell activation GO:0042110 289 0.084
aortic valve development GO:0003176 5 0.084
embryonic heart tube morphogenesis GO:0003143 51 0.084
branching involved in ureteric bud morphogenesis GO:0001658 56 0.083
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.083
bundle of his development GO:0003166 4 0.083
multicellular organismal homeostasis GO:0048871 164 0.083
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.082
sclerotome development GO:0061056 4 0.082
cardioblast proliferation GO:0003263 8 0.082
hormone secretion GO:0046879 128 0.081
hindbrain morphogenesis GO:0021575 46 0.081
spinal cord motor neuron migration GO:0097476 4 0.081
adult walking behavior GO:0007628 41 0.081
regulation of cytoskeleton organization GO:0051493 122 0.081
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.081
kidney development GO:0001822 213 0.080
somatotropin secreting cell differentiation GO:0060126 4 0.080
regulation of cardioblast proliferation GO:0003264 9 0.080
positive regulation of striated muscle tissue development GO:0045844 31 0.080
neuron death GO:0070997 154 0.079
negative regulation of peroxisome proliferator activated receptor signaling pathway GO:0035359 3 0.079
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.079
fourth ventricle development GO:0021592 2 0.078
central nervous system neuron development GO:0021954 67 0.078
mesenchyme morphogenesis GO:0072132 32 0.078
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.078
protein ubiquitination GO:0016567 171 0.078
negative regulation of neuron differentiation GO:0045665 101 0.078
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.078
mitochondrion distribution GO:0048311 4 0.077
developmental cell growth GO:0048588 84 0.077
positive regulation of cell activation GO:0050867 158 0.077
protein modification by small protein conjugation or removal GO:0070647 207 0.077
carbohydrate homeostasis GO:0033500 128 0.077
intestinal epithelial cell maturation GO:0060574 2 0.076
myotube cell development GO:0014904 60 0.076
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.076
single organism cell adhesion GO:0098602 156 0.076
vagus nerve development GO:0021564 3 0.075
artery development GO:0060840 53 0.075
bone morphogenesis GO:0060349 78 0.075
hindlimb morphogenesis GO:0035137 42 0.075
regulation of cardiac chamber morphogenesis GO:1901219 2 0.075
embryonic camera type eye development GO:0031076 36 0.075
hair follicle development GO:0001942 85 0.074
regulation of exit from mitosis GO:0007096 1 0.074
response to molecule of bacterial origin GO:0002237 143 0.074
mammary gland duct morphogenesis GO:0060603 38 0.074
neural tube patterning GO:0021532 43 0.074
dorsal ventral neural tube patterning GO:0021904 28 0.073
positive regulation of osteoblast differentiation GO:0045669 34 0.073
notch signaling pathway GO:0007219 71 0.072
regulation of cell adhesion GO:0030155 154 0.072
positive regulation of glial cell proliferation GO:0060252 4 0.071
cardiac septum development GO:0003279 59 0.071
regulation of secretion GO:0051046 274 0.070
regulation of cellular component size GO:0032535 121 0.070
neuron fate specification GO:0048665 30 0.070
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.070
negative regulation of protein metabolic process GO:0051248 282 0.070
regulation of leukocyte differentiation GO:1902105 159 0.070
regulation of epithelial to mesenchymal transition GO:0010717 22 0.069
cellular response to organonitrogen compound GO:0071417 145 0.069
multicellular organismal response to stress GO:0033555 62 0.069
biomineral tissue development GO:0031214 64 0.068
cochlea development GO:0090102 35 0.068
positive regulation of cell cycle GO:0045787 92 0.068
mesonephric tubule morphogenesis GO:0072171 63 0.068
endomembrane system organization GO:0010256 147 0.067
positive regulation of synaptic plasticity GO:0031915 4 0.067
female sex differentiation GO:0046660 84 0.067
development of primary male sexual characteristics GO:0046546 88 0.067
ectoderm formation GO:0001705 3 0.066
alpha beta t cell differentiation GO:0046632 69 0.066
sensory perception of mechanical stimulus GO:0050954 107 0.066
negative regulation of cellular protein metabolic process GO:0032269 247 0.065
sensory perception of sound GO:0007605 97 0.065
positive regulation of lymphocyte activation GO:0051251 140 0.064
erythrocyte maturation GO:0043249 6 0.064
endochondral bone morphogenesis GO:0060350 50 0.064
positive regulation of neuron projection development GO:0010976 79 0.063
cerebellar granule cell precursor proliferation GO:0021930 10 0.063
ventricular cardiac muscle tissue development GO:0003229 38 0.063
cardiac atrium morphogenesis GO:0003209 23 0.063
developmental programmed cell death GO:0010623 41 0.062
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.062
motor neuron axon guidance GO:0008045 26 0.062
regulation of protein complex assembly GO:0043254 83 0.062
mammary gland morphogenesis GO:0060443 54 0.062
ribonucleoside triphosphate catabolic process GO:0009203 199 0.061
cochlea morphogenesis GO:0090103 22 0.061
response to acid chemical GO:0001101 111 0.061
gliogenesis GO:0042063 141 0.061
response to organonitrogen compound GO:0010243 246 0.061
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.061
regulation of heart growth GO:0060420 31 0.061
innervation GO:0060384 22 0.060
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.060
chromatin modification GO:0016568 187 0.060
regulation of kinase activity GO:0043549 249 0.060
regulation of neural precursor cell proliferation GO:2000177 70 0.060
regulation of cellular response to growth factor stimulus GO:0090287 82 0.060
mesenchymal epithelial cell signaling involved in lung development GO:0060496 1 0.060
leukocyte mediated immunity GO:0002443 174 0.060
organic hydroxy compound biosynthetic process GO:1901617 77 0.060
regulation of transferase activity GO:0051338 263 0.060
striated muscle cell proliferation GO:0014855 39 0.059
paraxial mesodermal cell fate commitment GO:0048343 2 0.059
endocardial cushion to mesenchymal transition GO:0090500 5 0.059
gtp metabolic process GO:0046039 144 0.059
negative regulation of intracellular signal transduction GO:1902532 167 0.059
cell cell signaling involved in mammary gland development GO:0060764 2 0.059
paraxial mesodermal cell differentiation GO:0048342 2 0.059
regulation of protein kinase activity GO:0045859 232 0.059
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.059
hematopoietic progenitor cell differentiation GO:0002244 143 0.059
ureteric bud morphogenesis GO:0060675 62 0.059
odontogenesis of dentin containing tooth GO:0042475 66 0.058
covalent chromatin modification GO:0016569 163 0.058
columnar cuboidal epithelial cell maturation GO:0002069 4 0.058
renal tubule morphogenesis GO:0061333 72 0.058
regulation of cartilage development GO:0061035 44 0.057
intracellular receptor signaling pathway GO:0030522 74 0.057
his purkinje system cell differentiation GO:0060932 2 0.057

Shox2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.086
musculoskeletal system disease DOID:17 0 0.086
connective tissue disease DOID:65 0 0.086