Mus musculus

50 known processes

Siglec1

sialic acid binding Ig-like lectin 1, sialoadhesin

(Aliases: Cd169,Siglec-1,Sn)

Siglec1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytokine production GO:0001816 319 0.970
defense response to other organism GO:0098542 197 0.946
cytokine secretion GO:0050663 72 0.913
regulation of cytokine production GO:0001817 266 0.880
cation homeostasis GO:0055080 212 0.851
leukocyte activation involved in immune response GO:0002366 126 0.850
regulation of cell activation GO:0050865 289 0.836
regulation of inflammatory response GO:0050727 147 0.816
regulation of secretion GO:0051046 274 0.813
immune effector process GO:0002252 321 0.810
regulation of secretion by cell GO:1903530 249 0.796
leukocyte mediated immunity GO:0002443 174 0.755
defense response to bacterium GO:0042742 119 0.748
regulation of lymphocyte proliferation GO:0050670 117 0.735
sequestering of metal ion GO:0051238 19 0.732
defense response to gram positive bacterium GO:0050830 50 0.679
keratinocyte migration GO:0051546 3 0.676
positive regulation of leukocyte mediated immunity GO:0002705 70 0.630
regulation of leukocyte mediated immunity GO:0002703 104 0.629
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.603
release of sequestered calcium ion into cytosol GO:0051209 42 0.593
lymphocyte proliferation GO:0046651 164 0.586
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.570
positive regulation of cytokine production GO:0001819 174 0.558
chemotaxis GO:0006935 247 0.556
cation transport GO:0006812 399 0.534
amine metabolic process GO:0009308 45 0.521
positive regulation of macrophage chemotaxis GO:0010759 5 0.516
leukocyte proliferation GO:0070661 172 0.501
regulation of lymphocyte activation GO:0051249 240 0.489
cellular calcium ion homeostasis GO:0006874 119 0.488
regulation of defense response GO:0031347 233 0.481
calcium ion homeostasis GO:0055074 127 0.477
regulation of leukocyte proliferation GO:0070663 121 0.468
adaptive immune response GO:0002250 155 0.462
cellular ion homeostasis GO:0006873 165 0.439
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.433
cytosolic calcium ion transport GO:0060401 48 0.430
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.428
cellular metal ion homeostasis GO:0006875 151 0.418
regulation of system process GO:0044057 200 0.415
regulation of map kinase activity GO:0043405 120 0.415
regulation of lymphocyte mediated immunity GO:0002706 84 0.410
positive regulation of cytokine secretion GO:0050715 41 0.408
cytosolic calcium ion homeostasis GO:0051480 70 0.407
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.404
regulation of mapk cascade GO:0043408 248 0.402
maintenance of location GO:0051235 89 0.399
divalent inorganic cation transport GO:0072511 178 0.398
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.395
regulation of cytokine secretion GO:0050707 61 0.392
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.387
endocytosis GO:0006897 168 0.385
sequestering of calcium ion GO:0051208 18 0.380
regulation of innate immune response GO:0045088 91 0.376
positive regulation of monocyte chemotaxis GO:0090026 2 0.374
mononuclear cell migration GO:0071674 8 0.368
blood vessel morphogenesis GO:0048514 285 0.367
divalent metal ion transport GO:0070838 172 0.366
cytokine metabolic process GO:0042107 71 0.364
regulation of protein transport GO:0051223 163 0.364
lymphocyte mediated immunity GO:0002449 139 0.356
positive regulation of tumor necrosis factor production GO:0032760 30 0.355
cellular homeostasis GO:0019725 240 0.346
regulation of monocyte chemotaxis GO:0090025 3 0.344
membrane organization GO:0061024 245 0.339
positive regulation of cell migration GO:0030335 109 0.337
regulation of ion homeostasis GO:2000021 64 0.337
positive regulation of apoptotic process GO:0043065 217 0.336
mapk cascade GO:0000165 281 0.332
positive regulation of protein phosphorylation GO:0001934 242 0.331
positive regulation of immune effector process GO:0002699 107 0.328
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.324
innate immune response GO:0045087 157 0.323
regulation of protein secretion GO:0050708 82 0.320
production of molecular mediator of immune response GO:0002440 103 0.315
cellular divalent inorganic cation homeostasis GO:0072503 127 0.313
inflammatory response GO:0006954 244 0.311
organic anion transport GO:0015711 137 0.309
organic hydroxy compound transport GO:0015850 93 0.304
nucleobase containing small molecule metabolic process GO:0055086 352 0.303
b cell activation GO:0042113 161 0.302
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.300
activation of immune response GO:0002253 138 0.299
neutrophil chemotaxis GO:0030593 36 0.297
carbohydrate derivative biosynthetic process GO:1901137 183 0.287
metal ion homeostasis GO:0055065 189 0.284
negative regulation of immune system process GO:0002683 209 0.283
calcium ion transport into cytosol GO:0060402 48 0.283
divalent inorganic cation homeostasis GO:0072507 138 0.282
t cell proliferation GO:0042098 120 0.275
regulation of protein localization GO:0032880 231 0.275
cell activation involved in immune response GO:0002263 126 0.274
immune response activating signal transduction GO:0002757 116 0.272
positive regulation of defense response GO:0031349 124 0.271
tumor necrosis factor production GO:0032640 50 0.269
negative regulation of lymphocyte activation GO:0051250 91 0.267
ras protein signal transduction GO:0007265 77 0.264
regulation of ion transport GO:0043269 215 0.262
leukocyte differentiation GO:0002521 342 0.261
calcium ion transport GO:0006816 159 0.259
response to molecule of bacterial origin GO:0002237 143 0.259
positive regulation of secretion GO:0051047 130 0.257
positive regulation of protein modification process GO:0031401 299 0.257
positive regulation of cellular amine metabolic process GO:0033240 5 0.255
regulation of vesicle mediated transport GO:0060627 139 0.251
negative regulation of homeostatic process GO:0032845 71 0.249
cytokine biosynthetic process GO:0042089 68 0.249
blood circulation GO:0008015 195 0.248
positive regulation of thymocyte migration GO:2000412 2 0.248
regulation of cell motility GO:2000145 236 0.248
regulation of cellular amine metabolic process GO:0033238 20 0.242
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.242
positive regulation of adaptive immune response GO:0002821 61 0.242
cellular chemical homeostasis GO:0055082 215 0.240
organic cyclic compound catabolic process GO:1901361 295 0.240
carboxylic acid transport GO:0046942 100 0.235
regulation of cytokine biosynthetic process GO:0042035 59 0.233
positive regulation of transferase activity GO:0051347 167 0.231
regulation of b cell mediated immunity GO:0002712 37 0.230
positive regulation of cytokine biosynthetic process GO:0042108 40 0.229
rho protein signal transduction GO:0007266 32 0.228
regulation of kinase activity GO:0043549 249 0.228
regulation of exocytosis GO:0017157 61 0.226
immunoglobulin mediated immune response GO:0016064 69 0.226
positive regulation of protein transport GO:0051222 93 0.223
regulation of nucleotide metabolic process GO:0006140 169 0.220
cell recognition GO:0008037 83 0.218
immune response regulating signaling pathway GO:0002764 125 0.218
cellular amino acid metabolic process GO:0006520 103 0.216
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.214
phagocytosis GO:0006909 66 0.214
positive regulation of leukocyte proliferation GO:0070665 73 0.213
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.211
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.206
leukocyte migration GO:0050900 124 0.205
multicellular organismal signaling GO:0035637 91 0.204
positive regulation of mapk cascade GO:0043410 170 0.203
positive regulation of cell activation GO:0050867 158 0.202
cellular amine metabolic process GO:0044106 44 0.200
myeloid leukocyte differentiation GO:0002573 119 0.193
sodium ion transport GO:0006814 73 0.193
positive regulation of map kinase activity GO:0043406 84 0.193
positive regulation of lymphocyte proliferation GO:0050671 70 0.188
regulation of adaptive immune response GO:0002819 90 0.185
mature dendritic cell differentiation GO:0097029 3 0.182
myeloid cell differentiation GO:0030099 233 0.182
neutrophil migration GO:1990266 37 0.179
myeloid cell activation involved in immune response GO:0002275 34 0.177
regulation of stress activated mapk cascade GO:0032872 69 0.176
regulation of jnk cascade GO:0046328 62 0.172
angiogenesis GO:0001525 201 0.168
cellular response to lipopolysaccharide GO:0071222 77 0.167
regulation of mast cell activation GO:0033003 21 0.167
second messenger mediated signaling GO:0019932 73 0.167
positive regulation of secretion by cell GO:1903532 114 0.164
regulation of establishment of protein localization GO:0070201 181 0.163
positive regulation of angiogenesis GO:0045766 46 0.163
negative regulation of leukocyte mediated immunity GO:0002704 29 0.160
regulation of angiogenesis GO:0045765 81 0.160
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.160
protein secretion GO:0009306 111 0.160
positive regulation of kinase activity GO:0033674 155 0.159
regulation of cellular response to stress GO:0080135 159 0.158
regulation of cell migration GO:0030334 219 0.158
regulation of metal ion transport GO:0010959 106 0.155
organonitrogen compound biosynthetic process GO:1901566 192 0.153
cell killing GO:0001906 67 0.147
positive regulation of b cell mediated immunity GO:0002714 26 0.147
striated muscle contraction GO:0006941 45 0.147
regulation of endocytosis GO:0030100 69 0.147
interleukin 12 production GO:0032615 32 0.146
response to lipopolysaccharide GO:0032496 128 0.145
purine nucleotide biosynthetic process GO:0006164 65 0.144
regulation of wnt signaling pathway GO:0030111 123 0.144
negative regulation of cytokine production GO:0001818 84 0.142
small gtpase mediated signal transduction GO:0007264 97 0.140
myeloid leukocyte migration GO:0097529 57 0.140
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.140
leukocyte chemotaxis GO:0030595 69 0.139
cytoplasmic transport GO:0016482 234 0.138
morphogenesis of a branching epithelium GO:0061138 193 0.137
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.136
muscle cell differentiation GO:0042692 261 0.136
muscle system process GO:0003012 141 0.136
negative regulation of phagocytosis GO:0050765 4 0.135
ribonucleotide metabolic process GO:0009259 291 0.135
t cell activation GO:0042110 289 0.134
positive regulation of neutrophil chemotaxis GO:0090023 12 0.130
positive regulation of protein kinase activity GO:0045860 144 0.129
negative regulation of leukocyte proliferation GO:0070664 46 0.128
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.127
regulation of tumor necrosis factor production GO:0032680 49 0.126
reactive oxygen species metabolic process GO:0072593 84 0.125
regulation of epithelial cell proliferation GO:0050678 141 0.124
leukocyte mediated cytotoxicity GO:0001909 62 0.124
granulocyte chemotaxis GO:0071621 39 0.121
cytokine production involved in immune response GO:0002367 34 0.120
positive regulation of granulocyte chemotaxis GO:0071624 12 0.119
granulocyte migration GO:0097530 43 0.118
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.118
regulation of purine nucleotide metabolic process GO:1900542 169 0.118
macrophage chemotaxis GO:0048246 14 0.118
peptidyl amino acid modification GO:0018193 336 0.117
positive regulation of inflammatory response GO:0050729 47 0.117
glycoprotein biosynthetic process GO:0009101 89 0.116
regulation of t cell proliferation GO:0042129 92 0.115
positive regulation of calcium ion transport GO:0051928 27 0.115
mast cell activation involved in immune response GO:0002279 20 0.114
toll like receptor signaling pathway GO:0002224 38 0.114
regulation of chemotaxis GO:0050920 53 0.114
regulation of homeostatic process GO:0032844 182 0.113
glycoprotein metabolic process GO:0009100 116 0.113
positive regulation of interleukin 12 production GO:0032735 21 0.113
regulation of multi organism process GO:0043900 111 0.113
ameboidal type cell migration GO:0001667 128 0.112
nucleoside phosphate metabolic process GO:0006753 338 0.112
regulation of cellular amino acid metabolic process GO:0006521 5 0.111
lipid transport GO:0006869 98 0.111
positive regulation of behavior GO:0048520 40 0.111
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.109
receptor mediated endocytosis GO:0006898 51 0.108
circulatory system process GO:0003013 197 0.108
g protein coupled receptor signaling pathway GO:0007186 243 0.108
regulation of vasculature development GO:1901342 88 0.106
regulation of transferase activity GO:0051338 263 0.105
negative regulation of secretion GO:0051048 61 0.105
stress activated mapk cascade GO:0051403 80 0.105
positive regulation of eosinophil migration GO:2000418 2 0.105
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.102
mast cell activation GO:0045576 27 0.102
positive regulation of neutrophil migration GO:1902624 12 0.101
positive regulation of endocytosis GO:0045807 42 0.101
purine containing compound catabolic process GO:0072523 213 0.101
positive regulation of interleukin 8 production GO:0032757 2 0.100
nucleotide metabolic process GO:0009117 332 0.098
nucleoside metabolic process GO:0009116 246 0.098
positive regulation of camp mediated signaling GO:0043950 3 0.098
regulation of muscle tissue development GO:1901861 97 0.097
immunoglobulin production GO:0002377 73 0.096
positive regulation of jnk cascade GO:0046330 46 0.096
pattern recognition receptor signaling pathway GO:0002221 47 0.095
transmission of nerve impulse GO:0019226 76 0.095
regulation of interleukin 12 production GO:0032655 30 0.095
ribose phosphate metabolic process GO:0019693 291 0.095
positive regulation of nervous system development GO:0051962 221 0.094
inflammatory response to antigenic stimulus GO:0002437 30 0.092
positive regulation of response to wounding GO:1903036 66 0.092
exocytosis GO:0006887 121 0.092
positive regulation of chemotaxis GO:0050921 38 0.092
activation of mapk activity GO:0000187 59 0.092
positive regulation of phagocytosis GO:0050766 26 0.091
regulation of glial cell differentiation GO:0045685 41 0.090
lymphocyte activation involved in immune response GO:0002285 93 0.090
cellular response to growth factor stimulus GO:0071363 197 0.089
purine nucleotide metabolic process GO:0006163 302 0.089
epithelial tube morphogenesis GO:0060562 303 0.089
regulation of t cell activation GO:0050863 170 0.089
regulation of vascular endothelial growth factor production GO:0010574 13 0.087
regulation of neuron death GO:1901214 134 0.087
negative regulation of t cell activation GO:0050868 65 0.087
cellular response to biotic stimulus GO:0071216 92 0.087
heart contraction GO:0060047 93 0.086
neuron apoptotic process GO:0051402 142 0.086
organophosphate biosynthetic process GO:0090407 122 0.086
antigen processing and presentation GO:0019882 47 0.086
positive regulation of nucleotide metabolic process GO:0045981 114 0.086
defense response to virus GO:0051607 68 0.085
activation of jun kinase activity GO:0007257 15 0.085
regulation of muscle system process GO:0090257 80 0.085
t cell differentiation GO:0030217 174 0.084
purine ribonucleotide metabolic process GO:0009150 290 0.084
response to organic cyclic compound GO:0014070 198 0.084
regulation of t cell mediated immunity GO:0002709 34 0.084
glycosyl compound metabolic process GO:1901657 246 0.084
regulation of interleukin 8 production GO:0032677 3 0.083
negative regulation of lymphocyte proliferation GO:0050672 45 0.083
regulation of calcium ion transport into cytosol GO:0010522 31 0.083
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.082
ribonucleoside triphosphate catabolic process GO:0009203 199 0.082
gliogenesis GO:0042063 141 0.082
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.081
peptidyl tyrosine modification GO:0018212 145 0.081
aromatic compound catabolic process GO:0019439 286 0.081
striated muscle cell development GO:0055002 125 0.081
negative regulation of serotonin secretion GO:0014063 2 0.080
regulation of neutrophil chemotaxis GO:0090022 14 0.080
positive regulation of ion transport GO:0043270 65 0.080
cell chemotaxis GO:0060326 81 0.080
regulation of b cell proliferation GO:0030888 39 0.079
cellular response to molecule of bacterial origin GO:0071219 83 0.079
macromolecule catabolic process GO:0009057 281 0.078
neuron death GO:0070997 154 0.078
regulation of protein serine threonine kinase activity GO:0071900 157 0.077
regulation of protein kinase activity GO:0045859 232 0.077
forebrain development GO:0030900 302 0.076
epithelial cell proliferation GO:0050673 174 0.076
regulation of cellular ketone metabolic process GO:0010565 66 0.076
innate immune response activating signal transduction GO:0002758 50 0.075
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.075
fat cell differentiation GO:0045444 160 0.075
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.074
b cell mediated immunity GO:0019724 71 0.074
response to growth factor GO:0070848 198 0.073
vascular endothelial growth factor production GO:0010573 13 0.073
nitrogen compound transport GO:0071705 271 0.073
positive regulation of intracellular transport GO:0032388 70 0.072
neuronal action potential GO:0019228 54 0.072
carbohydrate metabolic process GO:0005975 230 0.072
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.072
cell type specific apoptotic process GO:0097285 268 0.072
erk1 and erk2 cascade GO:0070371 77 0.071
regulation of thymocyte migration GO:2000410 2 0.071
muscle cell proliferation GO:0033002 52 0.071
sensory perception GO:0007600 245 0.070
morphogenesis of a branching structure GO:0001763 203 0.070
gland development GO:0048732 330 0.070
positive regulation of ras gtpase activity GO:0032320 65 0.070
innate immune response in mucosa GO:0002227 3 0.070
protein catabolic process GO:0030163 221 0.069
jnk cascade GO:0007254 72 0.069
interspecies interaction between organisms GO:0044419 83 0.069
regulation of calcium ion transport GO:0051924 69 0.069
skeletal system morphogenesis GO:0048705 203 0.069
serotonin transport GO:0006837 11 0.069
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.068
t helper 2 cell cytokine production GO:0035745 4 0.067
coagulation GO:0050817 78 0.067
modification of morphology or physiology of other organism GO:0035821 18 0.066
purine containing compound metabolic process GO:0072521 311 0.066
organic acid transport GO:0015849 101 0.066
muscle contraction GO:0006936 101 0.066
negative regulation of cell activation GO:0050866 111 0.066
negative regulation of phosphorylation GO:0042326 166 0.066
negative regulation of t cell proliferation GO:0042130 38 0.065
cellular ketone metabolic process GO:0042180 84 0.065
eosinophil migration GO:0072677 3 0.065
regulation of response to wounding GO:1903034 189 0.064
response to organonitrogen compound GO:0010243 246 0.064
regulation of production of molecular mediator of immune response GO:0002700 65 0.063
regulation of intracellular transport GO:0032386 159 0.063
myeloid dendritic cell differentiation GO:0043011 16 0.063
action potential GO:0001508 78 0.062
ribonucleoside metabolic process GO:0009119 245 0.062
defense response to gram negative bacterium GO:0050829 28 0.062
positive regulation of innate immune response GO:0045089 80 0.062
regulation of reactive oxygen species metabolic process GO:2000377 40 0.062
cellular polysaccharide metabolic process GO:0044264 38 0.061
thymocyte migration GO:0072679 2 0.060
regulation of mononuclear cell migration GO:0071675 6 0.059
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.059
regulation of immunoglobulin mediated immune response GO:0002889 37 0.059
positive regulation of chemokine biosynthetic process GO:0045080 6 0.059
positive regulation of protein secretion GO:0050714 52 0.058
positive regulation of interferon gamma production GO:0032729 39 0.058
stress activated protein kinase signaling cascade GO:0031098 81 0.058
positive regulation of homeostatic process GO:0032846 64 0.058
dendritic cell differentiation GO:0097028 26 0.058
regulation of neurotransmitter levels GO:0001505 87 0.058
anatomical structure homeostasis GO:0060249 145 0.057
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.057
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.057
positive regulation of stress activated mapk cascade GO:0032874 48 0.057
cytokine mediated signaling pathway GO:0019221 115 0.057
regulation of granulocyte chemotaxis GO:0071622 17 0.056
glycosyl compound catabolic process GO:1901658 206 0.056
peptidyl tyrosine phosphorylation GO:0018108 143 0.056
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.056
negative regulation of immune effector process GO:0002698 55 0.055
regulation of striated muscle cell differentiation GO:0051153 81 0.055
lymphocyte differentiation GO:0030098 242 0.055
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.055
extracellular matrix organization GO:0030198 147 0.055
reactive oxygen species biosynthetic process GO:1903409 8 0.054
regulation of eosinophil migration GO:2000416 2 0.054
myeloid leukocyte activation GO:0002274 83 0.054
cellular nitrogen compound catabolic process GO:0044270 280 0.054
t cell mediated immunity GO:0002456 50 0.053
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.053
skeletal system development GO:0001501 356 0.053
muscle tissue development GO:0060537 308 0.053
striated muscle tissue development GO:0014706 293 0.053
acid secretion GO:0046717 33 0.052
regulation of t helper 2 cell cytokine production GO:2000551 3 0.052
cyclic nucleotide metabolic process GO:0009187 59 0.052
interferon gamma production GO:0032609 67 0.052
camp metabolic process GO:0046058 40 0.052
cardiac muscle tissue development GO:0048738 130 0.051
detection of stimulus GO:0051606 84 0.051
t cell extravasation GO:0072683 4 0.051
adult behavior GO:0030534 135 0.051
regulation of rho protein signal transduction GO:0035023 71 0.051
regulation of cellular component biogenesis GO:0044087 181 0.051
regulation of peptide secretion GO:0002791 77 0.051
response to peptidoglycan GO:0032494 9 0.050
regulation of protein kinase b signaling GO:0051896 56 0.049
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.049
regulation of calcium mediated signaling GO:0050848 19 0.049
inorganic cation transmembrane transport GO:0098662 207 0.049
regulation of blood pressure GO:0008217 93 0.049
sensory perception of pain GO:0019233 47 0.049
regulation of t cell costimulation GO:2000523 2 0.048
blood coagulation GO:0007596 76 0.048
interleukin 18 production GO:0032621 4 0.048
anion transport GO:0006820 177 0.048
transmembrane transport GO:0055085 412 0.048
carbohydrate derivative catabolic process GO:1901136 231 0.047
b cell proliferation GO:0042100 53 0.047
negative regulation of secretion by cell GO:1903531 54 0.047
lysosome localization GO:0032418 20 0.046
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.046
positive regulation of lymphocyte activation GO:0051251 140 0.046
negative regulation of growth of symbiont in host GO:0044130 19 0.046
cellular response to cytokine stimulus GO:0071345 189 0.046
regulation of myoblast differentiation GO:0045661 29 0.046
locomotory behavior GO:0007626 195 0.045
macromolecule glycosylation GO:0043413 55 0.045
leukocyte degranulation GO:0043299 27 0.045
mast cell degranulation GO:0043303 19 0.045
axonogenesis GO:0007409 274 0.045
antibacterial peptide secretion GO:0002779 1 0.044
positive regulation of lymphocyte migration GO:2000403 11 0.044
organelle localization GO:0051640 179 0.044
regulation of phagocytosis GO:0050764 33 0.044
negative regulation of exocytosis GO:0045920 12 0.044
positive regulation of interferon gamma biosynthetic process GO:0045078 4 0.044
positive regulation of leukocyte differentiation GO:1902107 86 0.044
ribonucleoside triphosphate metabolic process GO:0009199 220 0.044
regulation of t helper 1 cell cytokine production GO:2000554 1 0.044
purine ribonucleoside metabolic process GO:0046128 241 0.043
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.043
telencephalon cell migration GO:0022029 55 0.043
positive regulation of granulocyte macrophage colony stimulating factor production GO:0032725 3 0.043
osteoclast differentiation GO:0030316 62 0.042
negative regulation of adaptive immune response GO:0002820 25 0.042
regulation of muscle contraction GO:0006937 49 0.042
nucleoside phosphate catabolic process GO:1901292 222 0.042
synaptic transmission GO:0007268 329 0.042
fatty acid transport GO:0015908 28 0.042
regulation of b cell activation GO:0050864 81 0.042
cerebral cortex cell migration GO:0021795 44 0.042
ion transmembrane transport GO:0034220 361 0.042
purine nucleoside metabolic process GO:0042278 241 0.041
alpha beta t cell activation GO:0046631 91 0.041
cell cycle g1 s phase transition GO:0044843 57 0.041
cell adhesion GO:0007155 329 0.041
cellular response to lipid GO:0071396 145 0.041
negative regulation of cellular component organization GO:0051129 194 0.041
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.041
positive regulation of acute inflammatory response GO:0002675 16 0.041
regulation of camp metabolic process GO:0030814 30 0.041
regulation of apoptotic signaling pathway GO:2001233 197 0.040
regulation of fat cell differentiation GO:0045598 81 0.040
purine nucleoside triphosphate metabolic process GO:0009144 226 0.040
odontogenesis of dentin containing tooth GO:0042475 66 0.040
calcium mediated signaling GO:0019722 46 0.040
negative regulation of growth GO:0045926 99 0.040
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.040
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.040
leukocyte apoptotic process GO:0071887 71 0.040
cellular lipid metabolic process GO:0044255 323 0.040
ensheathment of neurons GO:0007272 76 0.039
intracellular protein transport GO:0006886 204 0.039
nucleoside phosphate biosynthetic process GO:1901293 79 0.039
regulation of interferon gamma production GO:0032649 57 0.039
regulation of natural killer cell chemotaxis GO:2000501 1 0.039
negative regulation of interleukin 13 secretion GO:2000666 1 0.039
regulation of cell projection organization GO:0031344 206 0.039
regulation of purine nucleotide catabolic process GO:0033121 122 0.039
glycosylation GO:0070085 62 0.039
axon guidance GO:0007411 141 0.039
peptide secretion GO:0002790 114 0.039
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.038
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.038
lipid localization GO:0010876 126 0.038
inorganic ion transmembrane transport GO:0098660 234 0.038
positive regulation of nucleoside metabolic process GO:0045979 91 0.038
regulation of blood circulation GO:1903522 93 0.038
myotube differentiation GO:0014902 105 0.038
b cell chemotaxis GO:0035754 3 0.038
protein localization to nucleus GO:0034504 121 0.037
b cell activation involved in immune response GO:0002312 50 0.037
negative regulation of eosinophil degranulation GO:0043310 1 0.037
learning or memory GO:0007611 148 0.037
growth of symbiont in host GO:0044117 23 0.037
purine nucleoside catabolic process GO:0006152 205 0.037
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.037
oligodendrocyte differentiation GO:0048709 53 0.037
membrane invagination GO:0010324 17 0.037
detection of yeast GO:0001879 2 0.037
regulation of monocyte extravasation GO:2000437 2 0.036
response to pain GO:0048265 26 0.036
protein glycosylation GO:0006486 55 0.036
regulation of heart contraction GO:0008016 77 0.036
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.036
nucleoside catabolic process GO:0009164 206 0.036
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.036
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.035

Siglec1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.058