|
|
protein deacetylation
|
GO:0006476 |
32 |
1.000
|
Human Yeast Worm |
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.999
|
Human Yeast Worm |
|
|
histone modification
|
GO:0016570 |
159 |
0.999
|
Human Yeast Worm |
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.996
|
Human Yeast Worm |
|
|
chromatin organization
|
GO:0006325 |
206 |
0.993
|
Human Yeast Worm |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.989
|
|
|
|
histone h4 deacetylation
|
GO:0070933 |
4 |
0.988
|
|
|
|
histone deacetylation
|
GO:0016575 |
26 |
0.987
|
Yeast Worm |
|
|
regulation of protein deacetylation
|
GO:0090311 |
17 |
0.984
|
|
|
|
histone h3 deacetylation
|
GO:0070932 |
8 |
0.974
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.966
|
Human Yeast Worm |
|
|
protein deacylation
|
GO:0035601 |
36 |
0.954
|
Human Yeast Worm |
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.947
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
14 |
0.914
|
Human |
|
|
histone methylation
|
GO:0016571 |
71 |
0.906
|
|
|
|
nucleosome disassembly
|
GO:0006337 |
1 |
0.892
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.883
|
Human |
|
|
regulation of histone methylation
|
GO:0031060 |
30 |
0.882
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.878
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.867
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.846
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.834
|
Human |
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.808
|
Human |
|
|
histone h3 k9 methylation
|
GO:0051567 |
17 |
0.804
|
|
|
|
regulation of transcription during meiosis
|
GO:0051037 |
1 |
0.797
|
Yeast |
|
|
maintenance of chromatin silencing
|
GO:0006344 |
2 |
0.754
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.734
|
Human Yeast Worm |
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.725
|
Human |
|
|
rhythmic process
|
GO:0048511 |
174 |
0.715
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.695
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.670
|
|
|
|
regulation of sarcomere organization
|
GO:0060297 |
4 |
0.653
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.650
|
Human |
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.643
|
Human |
|
|
protein methylation
|
GO:0006479 |
81 |
0.640
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.616
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.591
|
|
|
|
double strand break repair
|
GO:0006302 |
48 |
0.569
|
Yeast |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.568
|
|
|
|
exocrine pancreas development
|
GO:0031017 |
7 |
0.567
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.555
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.551
|
|
|
|
gene silencing by rna
|
GO:0031047 |
19 |
0.535
|
Worm |
|
|
dna modification
|
GO:0006304 |
50 |
0.533
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.522
|
|
|
|
chromatin silencing at rdna
|
GO:0000183 |
3 |
0.487
|
Yeast |
|
|
blastocyst growth
|
GO:0001832 |
23 |
0.466
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.460
|
|
|
|
histone demethylation
|
GO:0016577 |
13 |
0.451
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.444
|
|
|
|
eyelid development in camera type eye
|
GO:0061029 |
9 |
0.433
|
|
|
|
demethylation
|
GO:0070988 |
23 |
0.433
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.430
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.410
|
|
|
|
chromatin disassembly
|
GO:0031498 |
1 |
0.408
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.406
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.402
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.398
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.394
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.381
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.375
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.362
|
Yeast |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.358
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.355
|
Human |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.352
|
|
|
|
regulation of histone deacetylation
|
GO:0031063 |
12 |
0.352
|
|
|
|
histone h3 k9 acetylation
|
GO:0043970 |
5 |
0.345
|
|
|
|
viral gene expression
|
GO:0019080 |
3 |
0.344
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.341
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.338
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.337
|
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
2 |
0.334
|
Human Yeast |
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.329
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
3 |
0.326
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.325
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.315
|
|
|
|
histone h4 k16 acetylation
|
GO:0043984 |
3 |
0.311
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.311
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.311
|
|
|
|
protein demethylation
|
GO:0006482 |
13 |
0.307
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.304
|
Human |
|
|
blastocyst formation
|
GO:0001825 |
33 |
0.302
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.296
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.293
|
Human |
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.290
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.289
|
Human |
|
|
histone lysine demethylation
|
GO:0070076 |
13 |
0.289
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.283
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.273
|
|
|
|
dna alkylation
|
GO:0006305 |
43 |
0.269
|
|
|
|
negative regulation of androgen receptor signaling pathway
|
GO:0060766 |
3 |
0.258
|
|
|
|
male meiosis
|
GO:0007140 |
37 |
0.256
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
15 |
0.256
|
Human Yeast |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.249
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
10 |
0.248
|
Worm |
|
|
receptor biosynthetic process
|
GO:0032800 |
3 |
0.246
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.244
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.243
|
Fly |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.239
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.237
|
|
|
|
toxin transport
|
GO:1901998 |
38 |
0.236
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.235
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.233
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.230
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.222
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.221
|
|
|
|
dna conformation change
|
GO:0071103 |
37 |
0.220
|
|
|
|
dna dealkylation
|
GO:0035510 |
11 |
0.216
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.213
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.212
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.208
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.207
|
Human |
|
|
forebrain development
|
GO:0030900 |
302 |
0.207
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.207
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.206
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.204
|
|
|
|
chromatin silencing
|
GO:0006342 |
15 |
0.202
|
Human Yeast |
|
|
diencephalon development
|
GO:0021536 |
63 |
0.200
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.197
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.196
|
Yeast |
|
|
metencephalon development
|
GO:0022037 |
89 |
0.192
|
|
|
|
citrate metabolic process
|
GO:0006101 |
3 |
0.188
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.188
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.187
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
55 |
0.187
|
|
|
|
regulation of histone h3 k4 methylation
|
GO:0051569 |
12 |
0.186
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.184
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.184
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
19 |
0.183
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.182
|
Human |
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.179
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.178
|
|
|
|
negative regulation of histone modification
|
GO:0031057 |
18 |
0.175
|
Human |
|
|
appendage development
|
GO:0048736 |
166 |
0.174
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.172
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.171
|
|
|
|
regulation of cell cycle g2 m phase transition
|
GO:1902749 |
10 |
0.171
|
|
|
|
peptidyl lysine methylation
|
GO:0018022 |
29 |
0.169
|
|
|
|
rna interference
|
GO:0016246 |
2 |
0.169
|
Worm |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.167
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
28 |
0.165
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.163
|
|
|
|
interaction with symbiont
|
GO:0051702 |
14 |
0.163
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.162
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
3 |
0.160
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
28 |
0.150
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.148
|
Fly |
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.145
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.143
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.141
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.139
|
|
|
|
inner cell mass cell differentiation
|
GO:0001826 |
7 |
0.136
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
10 |
0.134
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.133
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.132
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.129
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.126
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.124
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.124
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.121
|
|
|
|
neural nucleus development
|
GO:0048857 |
22 |
0.121
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.121
|
|
|
|
negative regulation of histone methylation
|
GO:0031061 |
10 |
0.121
|
|
|
|
positive regulation of receptor biosynthetic process
|
GO:0010870 |
1 |
0.116
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.115
|
|
|
|
protein dna complex disassembly
|
GO:0032986 |
1 |
0.113
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.112
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.111
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
30 |
0.110
|
Human |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.110
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.109
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.109
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.108
|
Human |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.108
|
Human |
|
|
hair cycle
|
GO:0042633 |
90 |
0.107
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.107
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.106
|
Human |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.106
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.106
|
|
|
|
fungiform papilla morphogenesis
|
GO:0061197 |
5 |
0.104
|
|
|
|
definitive erythrocyte differentiation
|
GO:0060318 |
7 |
0.103
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.103
|
|
|
|
definitive hemopoiesis
|
GO:0060216 |
20 |
0.103
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.103
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.103
|
Yeast |
|
|
negative regulation of fat cell differentiation
|
GO:0045599 |
36 |
0.102
|
|
|
|
protein dealkylation
|
GO:0008214 |
13 |
0.102
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.102
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.101
|
|
|
|
substantia nigra development
|
GO:0021762 |
2 |
0.100
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.099
|
Mouse |
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.098
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.098
|
Mouse |
|
|
peptidyl lysine trimethylation
|
GO:0018023 |
12 |
0.098
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.097
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.096
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.096
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.096
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.095
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.095
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.094
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.093
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.093
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.093
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.090
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.089
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.089
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.089
|
|
|
|
viral transcription
|
GO:0019083 |
3 |
0.087
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.086
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.086
|
|
|
|
regulation of receptor biosynthetic process
|
GO:0010869 |
2 |
0.086
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.085
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.085
|
Worm |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.084
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.084
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
34 |
0.083
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.083
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.083
|
|
|
|
regulation of androgen receptor signaling pathway
|
GO:0060765 |
3 |
0.083
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.082
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.082
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.081
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
33 |
0.080
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.080
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.079
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.076
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.076
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.076
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.075
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.074
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.074
|
Fly |
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.073
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.072
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
29 |
0.072
|
|
|
|
hair follicle placode formation
|
GO:0060789 |
5 |
0.071
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.070
|
|
|
|
male germ line sex determination
|
GO:0019100 |
2 |
0.070
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.069
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.069
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.068
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.067
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.066
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.066
|
|
|
|
bone mineralization
|
GO:0030282 |
54 |
0.066
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.065
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.064
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.064
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.064
|
|
|
|
proprioception
|
GO:0019230 |
4 |
0.063
|
|
|
|
sterol homeostasis
|
GO:0055092 |
45 |
0.063
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.063
|
Human |
|
|
circadian behavior
|
GO:0048512 |
13 |
0.062
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.062
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.062
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.061
|
|
|
|
ectodermal cell fate commitment
|
GO:0001712 |
1 |
0.060
|
|
|
|
dna demethylation
|
GO:0080111 |
10 |
0.060
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.059
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.059
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
8 |
0.059
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
16 |
0.059
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.058
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.057
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.057
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.056
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.056
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.055
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.055
|
|
|
|
cellular respiration
|
GO:0045333 |
38 |
0.055
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.054
|
|
|
|
negative regulation of heart growth
|
GO:0061117 |
7 |
0.054
|
|
|
|
atp dependent chromatin remodeling
|
GO:0043044 |
9 |
0.054
|
|
|
|
regulation of heart growth
|
GO:0060420 |
31 |
0.054
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.053
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.053
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.053
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.053
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.053
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.052
|
Worm |
|
|
positive regulation of oligodendrocyte differentiation
|
GO:0048714 |
9 |
0.052
|
|
|
|
chromatin mediated maintenance of transcription
|
GO:0048096 |
2 |
0.052
|
|
|
|
dna replication
|
GO:0006260 |
52 |
0.052
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
3 |
0.052
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.052
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.052
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.050
|
Fly |
|
|
negative regulation of cardiac muscle tissue development
|
GO:0055026 |
8 |
0.050
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.050
|
|
|
|
regulation of asymmetric cell division
|
GO:0009786 |
4 |
0.049
|
|
|
|
transcription from rna polymerase iii promoter
|
GO:0006383 |
3 |
0.049
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.049
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.047
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.047
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.047
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.047
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.046
|
|
|
|
ectodermal placode formation
|
GO:0060788 |
16 |
0.046
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.046
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.046
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.046
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
21 |
0.045
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.045
|
|
|
|
granulocyte differentiation
|
GO:0030851 |
17 |
0.045
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.044
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
3 |
0.044
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.044
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.044
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
28 |
0.044
|
|
|
|
endoderm development
|
GO:0007492 |
45 |
0.044
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.043
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.043
|
Human |
|
|
multi organism metabolic process
|
GO:0044033 |
7 |
0.043
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.043
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.042
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.042
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.042
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.042
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.042
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.042
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.042
|
|
|
|
negative regulation of chromatin modification
|
GO:1903309 |
19 |
0.041
|
Human |
|
|
synapse organization
|
GO:0050808 |
125 |
0.041
|
|
|
|
modification by host of symbiont morphology or physiology
|
GO:0051851 |
12 |
0.041
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.041
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.041
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.040
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.040
|
|
|
|
telomere capping
|
GO:0016233 |
4 |
0.040
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.040
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.040
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.039
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.039
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.038
|
|
|
|
tricarboxylic acid metabolic process
|
GO:0072350 |
5 |
0.038
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.038
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.038
|
Human |
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.038
|
|
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
8 |
0.038
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.038
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.037
|
|
|
|
locomotor rhythm
|
GO:0045475 |
8 |
0.037
|
|
|
|
negative regulation of histone h3 k9 methylation
|
GO:0051573 |
4 |
0.037
|
|
|
|
fungiform papilla development
|
GO:0061196 |
6 |
0.037
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.037
|
|
|
|
transdifferentiation
|
GO:0060290 |
1 |
0.037
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.037
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.037
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.036
|
|
|
|
chromatin remodeling
|
GO:0006338 |
32 |
0.036
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.036
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.036
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.036
|
|
|
|
protein o linked glycosylation
|
GO:0006493 |
16 |
0.036
|
|
|
|
regulation of dna methylation
|
GO:0044030 |
12 |
0.035
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.035
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.035
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.035
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.034
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
18 |
0.034
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.033
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.033
|
Yeast |
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.033
|
|
|
|
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
|
GO:0014834 |
3 |
0.033
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.033
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.033
|
Human |
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.033
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.033
|
|
|
|
nucleosome positioning
|
GO:0016584 |
4 |
0.033
|
|
|
|
pons development
|
GO:0021548 |
13 |
0.032
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.032
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
3 |
0.032
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.032
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.032
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.031
|
|
|
|
spinal cord development
|
GO:0021510 |
81 |
0.031
|
|
|
|
embryonic digestive tract development
|
GO:0048566 |
27 |
0.031
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.031
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.031
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.031
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.031
|
Worm Fly |
|
|
epithalamus development
|
GO:0021538 |
2 |
0.031
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.031
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.031
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.031
|
|
|
|
facial nucleus development
|
GO:0021754 |
2 |
0.031
|
|
|
|
sarcomere organization
|
GO:0045214 |
24 |
0.030
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.030
|
|
|
|
regulation of histone h3 k9 methylation
|
GO:0051570 |
8 |
0.030
|
|
|
|
lung cell differentiation
|
GO:0060479 |
30 |
0.030
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.029
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.029
|
Human |
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.029
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.029
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.029
|
|
|
|
negative regulation of histone deacetylation
|
GO:0031064 |
2 |
0.029
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.029
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.029
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.029
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.029
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.029
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.029
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.028
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.028
|
|
|
|
pancreas development
|
GO:0031016 |
57 |
0.028
|
|
|
|
response to gamma radiation
|
GO:0010332 |
22 |
0.028
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.028
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.028
|
|
|
|
dna templated transcriptional preinitiation complex assembly
|
GO:0070897 |
4 |
0.028
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
28 |
0.028
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.028
|
|
|
|
lung epithelium development
|
GO:0060428 |
37 |
0.028
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.027
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.027
|
|
|
|
cardiac muscle cell development
|
GO:0055013 |
39 |
0.027
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.027
|
|
|
|
ectodermal placode development
|
GO:0071696 |
16 |
0.027
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.027
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.027
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.027
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
33 |
0.027
|
|
|
|
stem cell fate specification
|
GO:0048866 |
3 |
0.026
|
|
|
|
cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0002361 |
4 |
0.026
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.026
|
|
|
|
schwann cell development
|
GO:0014044 |
22 |
0.026
|
|
|
|
negative regulation of circadian rhythm
|
GO:0042754 |
8 |
0.026
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.026
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.026
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.026
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.026
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.026
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.025
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.025
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.025
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
21 |
0.025
|
|
|
|
germ line stem cell division
|
GO:0042078 |
2 |
0.025
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.025
|
|
|
|
negative regulation of hormone secretion
|
GO:0046888 |
20 |
0.025
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
35 |
0.024
|
|
|
|
negative regulation of cardiac muscle cell proliferation
|
GO:0060044 |
5 |
0.024
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.024
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.024
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.024
|
Mouse |
|
|
pyruvate metabolic process
|
GO:0006090 |
28 |
0.024
|
|
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
3 |
0.024
|
|
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
3 |
0.024
|
|
|
|
cardiac muscle cell proliferation
|
GO:0060038 |
31 |
0.024
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.024
|
|
|
|
chemokine c x c motif ligand 2 production
|
GO:0072567 |
3 |
0.024
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.024
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.024
|
|
|
|
negative regulation of viral transcription
|
GO:0032897 |
3 |
0.023
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.023
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.023
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.023
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.023
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.023
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
23 |
0.023
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.023
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
4 |
0.023
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.022
|
|
|
|
neural tube patterning
|
GO:0021532 |
43 |
0.022
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.022
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.022
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.022
|
Mouse |
|
|
gliogenesis
|
GO:0042063 |
141 |
0.022
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.022
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
39 |
0.022
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.022
|
|
|
|
ventricular compact myocardium morphogenesis
|
GO:0003223 |
2 |
0.022
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.022
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.021
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.021
|
|
|
|
histone h3 k9 dimethylation
|
GO:0036123 |
4 |
0.021
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.021
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.021
|
|
|
|
histone h3 k4 trimethylation
|
GO:0080182 |
5 |
0.021
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.021
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.021
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
29 |
0.020
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.020
|
|
|
|
mesoderm formation
|
GO:0001707 |
62 |
0.020
|
|
|
|
mrna transcription from rna polymerase ii promoter
|
GO:0042789 |
4 |
0.020
|
|
|
|
protein autoprocessing
|
GO:0016540 |
2 |
0.020
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
10 |
0.020
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.020
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.020
|
|
