|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.834
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.578
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.573
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.565
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.535
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.535
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.497
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.475
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.433
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.432
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.410
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.386
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.355
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.336
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.335
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.335
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.332
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.332
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.325
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.316
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.311
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.300
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.294
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.282
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.267
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.262
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.262
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.260
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.257
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.255
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.253
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.242
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.231
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.225
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.225
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.220
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.219
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.218
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.215
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.214
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.207
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.205
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.202
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.194
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.193
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.192
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.189
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.188
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.186
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.186
|
|
|
|
regulation of cardiac cell fate specification
|
GO:2000043 |
1 |
0.185
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.184
|
|
|
|
stem cell fate specification
|
GO:0048866 |
3 |
0.183
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.181
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.179
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.179
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.177
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.176
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.176
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.174
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.170
|
|
|
|
regulation of protein deacetylation
|
GO:0090311 |
17 |
0.168
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.164
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.162
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.160
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.156
|
|
|
|
cerebellar granule cell precursor tangential migration
|
GO:0021935 |
1 |
0.154
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.154
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.152
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.150
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.145
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.144
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.144
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.140
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.139
|
|
|
|
endocardial cell differentiation
|
GO:0060956 |
4 |
0.137
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.133
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.133
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.127
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.126
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.125
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.124
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.124
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.124
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.124
|
|
|
|
rhombomere morphogenesis
|
GO:0021593 |
2 |
0.124
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.123
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.122
|
Zebrafish |
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
4 |
0.121
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.120
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.119
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.118
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.118
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.118
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.117
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.116
|
Human |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.115
|
|
|
|
compartment pattern specification
|
GO:0007386 |
4 |
0.115
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.113
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.113
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.113
|
Human |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.112
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.112
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.112
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.112
|
Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.111
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.109
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.109
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.108
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.103
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.103
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.102
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.102
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.101
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.100
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.099
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.098
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.096
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.096
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.096
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.095
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.094
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.094
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.094
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.093
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.092
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.091
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.091
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.090
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.088
|
|
|
|
regulation of skeletal muscle adaptation
|
GO:0014733 |
12 |
0.087
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.087
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
72 |
0.086
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.086
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.085
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.084
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.084
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.084
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.084
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.084
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.083
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.083
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.083
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.082
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.082
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.082
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.082
|
|
|
|
positive regulation of mesoderm development
|
GO:2000382 |
2 |
0.082
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.081
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.081
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.080
|
Mouse |
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.079
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.079
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.078
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.078
|
Zebrafish |
|
|
bone development
|
GO:0060348 |
120 |
0.078
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.078
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.078
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.077
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.077
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.076
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.076
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.075
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.075
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.075
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.074
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.074
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.074
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.073
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.073
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.073
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.072
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.072
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.072
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.072
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.072
|
|
|
|
forebrain radial glial cell differentiation
|
GO:0021861 |
4 |
0.072
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.071
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.071
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.071
|
|
|
|
cellular response to fluid shear stress
|
GO:0071498 |
4 |
0.070
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.070
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.069
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.069
|
|
|
|
regulation of muscle adaptation
|
GO:0043502 |
31 |
0.068
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.068
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.068
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.067
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.066
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.066
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.066
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.065
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.065
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.062
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.062
|
|
|
|
clara cell differentiation
|
GO:0060486 |
4 |
0.062
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.062
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.061
|
Mouse |
|
|
lung cell differentiation
|
GO:0060479 |
30 |
0.061
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.061
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.061
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
30 |
0.061
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.060
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.060
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.060
|
|
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.060
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.058
|
|
|
|
cardiac right atrium morphogenesis
|
GO:0003213 |
3 |
0.058
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.058
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.058
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.058
|
Zebrafish |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.058
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.057
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.057
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.057
|
|
|
|
striated muscle adaptation
|
GO:0014888 |
26 |
0.057
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.056
|
Zebrafish |
|
|
myelination in peripheral nervous system
|
GO:0022011 |
19 |
0.056
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
52 |
0.055
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.055
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.055
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.055
|
Human |
|
|
apical constriction
|
GO:0003383 |
4 |
0.055
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.055
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.055
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.054
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.054
|
Human |
|
|
negative regulation of osteoblast differentiation
|
GO:0045668 |
30 |
0.053
|
Human |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.053
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.053
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.053
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.052
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.052
|
|
|
|
response to inactivity
|
GO:0014854 |
4 |
0.051
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.051
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.051
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.051
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.051
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.051
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.051
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.051
|
|
|
|
response to fluid shear stress
|
GO:0034405 |
7 |
0.051
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.051
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.050
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.050
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.050
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.050
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.050
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.050
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.049
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.049
|
|
|
|
pigment accumulation
|
GO:0043476 |
1 |
0.049
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.049
|
|
|
|
somite development
|
GO:0061053 |
81 |
0.049
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.049
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.049
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.049
|
Mouse |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.049
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.049
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.049
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.049
|
|
|
|
palate development
|
GO:0060021 |
76 |
0.049
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.048
|
Mouse |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.048
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.048
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.048
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.047
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.047
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.047
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.047
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.047
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.047
|
|
|
|
protein localization to cell junction
|
GO:1902414 |
3 |
0.047
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.047
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.047
|
Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.047
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.046
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.046
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.046
|
|
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.045
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.045
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.045
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.045
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.045
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.045
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.044
|
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
53 |
0.044
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.044
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
41 |
0.044
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
3 |
0.044
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.044
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.044
|
|
|
|
neuroblast fate commitment
|
GO:0014017 |
1 |
0.044
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.044
|
|
|
|
negative regulation of fat cell differentiation
|
GO:0045599 |
36 |
0.043
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.043
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.043
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.043
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.043
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.043
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.042
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.042
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.042
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.042
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.042
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.042
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.041
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.041
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.041
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.041
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
46 |
0.041
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.040
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.040
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.040
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.040
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
62 |
0.040
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.040
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.040
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.040
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.040
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.040
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.039
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.039
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.039
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.039
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.039
|
|
|
|
protein deacetylation
|
GO:0006476 |
32 |
0.039
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.039
|
|
|
|
mesoderm formation
|
GO:0001707 |
62 |
0.039
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.038
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.038
|
|
|
|
endoderm development
|
GO:0007492 |
45 |
0.038
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.038
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.038
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.038
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.038
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.038
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.038
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.038
|
|
|
|
endothelium development
|
GO:0003158 |
45 |
0.037
|
|
|
|
sulfur compound biosynthetic process
|
GO:0044272 |
37 |
0.037
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.037
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.037
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.037
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
50 |
0.037
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.036
|
Zebrafish |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.036
|
Zebrafish |
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.036
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.036
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.036
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.036
|
Zebrafish |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.036
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.036
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
13 |
0.035
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.035
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.035
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.035
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.035
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.035
|
|
|
|
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis
|
GO:2000148 |
1 |
0.035
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.035
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.035
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.035
|
Human |
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
30 |
0.035
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.035
|
|
|
|
regulation of cell migration involved in sprouting angiogenesis
|
GO:0090049 |
4 |
0.035
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.034
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.034
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.034
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.034
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.034
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.034
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.034
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.034
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.033
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.033
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.033
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.033
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.033
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.033
|
|
|
|
regulation of hippo signaling
|
GO:0035330 |
1 |
0.033
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.033
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.032
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.032
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.032
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.032
|
Mouse |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.032
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.031
|
|
|
|
schwann cell differentiation
|
GO:0014037 |
26 |
0.031
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.031
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.031
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.031
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.031
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.031
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.031
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.031
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.031
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.031
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.031
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.031
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.030
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.030
|
|
|
|
metanephric loop of henle development
|
GO:0072236 |
4 |
0.030
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.030
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.030
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.030
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.030
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.030
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.030
|
|
|
|
positive regulation of receptor activity
|
GO:2000273 |
17 |
0.030
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.030
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.030
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.030
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.030
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.030
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.029
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.029
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.029
|
|
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.029
|
|
|
|
neuroblast fate determination
|
GO:0007400 |
1 |
0.029
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.029
|
|
|
|
regulation of chondrocyte differentiation
|
GO:0032330 |
33 |
0.029
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.029
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.029
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
47 |
0.029
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
29 |
0.029
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.029
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.028
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.028
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.028
|
|
|
|
chemorepulsion of branchiomotor axon
|
GO:0021793 |
1 |
0.028
|
|
|
|
neural tube patterning
|
GO:0021532 |
43 |
0.028
|
|
|
|
positive regulation of cell proliferation involved in heart valve morphogenesis
|
GO:0003251 |
1 |
0.028
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.028
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.028
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
21 |
0.028
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.028
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.028
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.028
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.028
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.028
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.028
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.028
|
|
|
|
cellular response to acidic ph
|
GO:0071468 |
4 |
0.027
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
29 |
0.027
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.027
|
|
|
|
negative regulation of osteoblast proliferation
|
GO:0033689 |
4 |
0.027
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.027
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.027
|
|
|
|
metanephric mesenchyme morphogenesis
|
GO:0072133 |
4 |
0.027
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.027
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.027
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.027
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
68 |
0.027
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.027
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.027
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.026
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.026
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.026
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.026
|
|
|
|
growth involved in heart morphogenesis
|
GO:0003241 |
4 |
0.026
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.026
|
|
|
|
detection of chemical stimulus involved in sensory perception of taste
|
GO:0050912 |
3 |
0.026
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.026
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.026
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.026
|
|
|
|
anatomical structure maturation
|
GO:0071695 |
49 |
0.026
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.026
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.026
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.025
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.025
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.025
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
22 |
0.025
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.025
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.025
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.025
|
|
|
|
foregut morphogenesis
|
GO:0007440 |
12 |
0.025
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.025
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.025
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.025
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.025
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.025
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.025
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.025
|
|
|
|
pigment cell differentiation
|
GO:0050931 |
27 |
0.025
|
|
|
|
neuroblast differentiation
|
GO:0014016 |
2 |
0.025
|
|
|
|
response to ph
|
GO:0009268 |
14 |
0.025
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.025
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.025
|
|
