Mus musculus

31 known processes

Slc9a3

solute carrier family 9 (sodium/hydrogen exchanger), member 3

(Aliases: 9030624O13Rik,NHE-3,NHE3,AI930210)

Slc9a3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chloride transport GO:0006821 32 0.678
sodium ion transmembrane transport GO:0035725 49 0.640
regulation of ph GO:0006885 26 0.552
anion transport GO:0006820 177 0.532
Zebrafish Worm
inorganic anion transport GO:0015698 43 0.497
Zebrafish
transmembrane transport GO:0055085 412 0.441
regulation of chloride transport GO:2001225 2 0.305
ion transmembrane transport GO:0034220 361 0.302
hydrogen ion transmembrane transport GO:1902600 25 0.298
inorganic ion transmembrane transport GO:0098660 234 0.282
cation transmembrane transport GO:0098655 266 0.255
regulation of cellular ph GO:0030641 12 0.237
Worm
inorganic anion transmembrane transport GO:0098661 29 0.230
Zebrafish
organic anion transport GO:0015711 137 0.225
Worm
camera type eye development GO:0043010 266 0.198
hypotonic response GO:0006971 3 0.184
sodium ion transport GO:0006814 73 0.151
monovalent inorganic cation homeostasis GO:0055067 33 0.135
chloride transmembrane transport GO:1902476 24 0.128
inorganic cation transmembrane transport GO:0098662 207 0.127
anion transmembrane transport GO:0098656 71 0.125
Zebrafish
cation transport GO:0006812 399 0.125
synaptic transmission GO:0007268 329 0.117
g protein coupled receptor signaling pathway GO:0007186 243 0.111
nitrogen compound transport GO:0071705 271 0.105
Zebrafish Worm
carboxylic acid transport GO:0046942 100 0.103
Worm
cellular ion homeostasis GO:0006873 165 0.097
Worm
inner ear receptor cell development GO:0060119 39 0.093
regulation of synaptic transmission gabaergic GO:0032228 17 0.091
response to radiation GO:0009314 165 0.080
cation homeostasis GO:0055080 212 0.079
cellular amine metabolic process GO:0044106 44 0.079
cellular chemical homeostasis GO:0055082 215 0.073
Worm
regulation of intracellular ph GO:0051453 11 0.065
regulation of anion transport GO:0044070 27 0.062
Worm
purine nucleotide metabolic process GO:0006163 302 0.062
organic acid transport GO:0015849 101 0.062
Worm
peptide transport GO:0015833 133 0.061
Worm
sensory perception of light stimulus GO:0050953 54 0.060
neuron neuron synaptic transmission GO:0007270 69 0.057
eye photoreceptor cell differentiation GO:0001754 41 0.056
nucleotide metabolic process GO:0009117 332 0.055
positive regulation of cellular ph reduction GO:0032849 2 0.053
lipid biosynthetic process GO:0008610 179 0.052
hydrogen transport GO:0006818 35 0.051
nucleoside metabolic process GO:0009116 246 0.051
purine nucleoside metabolic process GO:0042278 241 0.051
multicellular organism growth GO:0035264 161 0.050
Worm
cellular homeostasis GO:0019725 240 0.049
Worm
lipid transport GO:0006869 98 0.048
Worm
sodium ion import GO:0097369 1 0.046
Zebrafish
proton transport GO:0015992 35 0.046
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.046
steroid metabolic process GO:0008202 119 0.046
sensory organ morphogenesis GO:0090596 242 0.045
cellular lipid metabolic process GO:0044255 323 0.044
skin development GO:0043588 220 0.044
response to light stimulus GO:0009416 135 0.044
nucleoside phosphate metabolic process GO:0006753 338 0.043
organic hydroxy compound metabolic process GO:1901615 203 0.042
maintenance of location GO:0051235 89 0.041
Worm
positive regulation of growth GO:0045927 104 0.041
Worm
synaptic transmission gabaergic GO:0051932 19 0.041
regulation of cellular ketone metabolic process GO:0010565 66 0.041
regulation of ion transport GO:0043269 215 0.040
Worm
amide transport GO:0042886 138 0.040
Worm
lipid localization GO:0010876 126 0.039
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
organic hydroxy compound transport GO:0015850 93 0.037
cellular nitrogen compound catabolic process GO:0044270 280 0.036
monocarboxylic acid transport GO:0015718 44 0.035
Worm
photoreceptor cell differentiation GO:0046530 52 0.035
small gtpase mediated signal transduction GO:0007264 97 0.034
heterocycle catabolic process GO:0046700 280 0.034
response to lipopolysaccharide GO:0032496 128 0.034
response to molecule of bacterial origin GO:0002237 143 0.034
carbohydrate derivative biosynthetic process GO:1901137 183 0.033
organonitrogen compound biosynthetic process GO:1901566 192 0.033
regulation of neuron differentiation GO:0045664 281 0.033
regulation of cell motility GO:2000145 236 0.033
retina development in camera type eye GO:0060041 119 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
nucleoside triphosphate metabolic process GO:0009141 230 0.032
ribose phosphate metabolic process GO:0019693 291 0.032
monocarboxylic acid metabolic process GO:0032787 191 0.032
cochlear nucleus development GO:0021747 4 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
regulation of hormone levels GO:0010817 211 0.030
ear development GO:0043583 200 0.030
aromatic compound catabolic process GO:0019439 286 0.030
organonitrogen compound catabolic process GO:1901565 264 0.030
mechanoreceptor differentiation GO:0042490 67 0.030
visual perception GO:0007601 52 0.030
purine containing compound metabolic process GO:0072521 311 0.029
regulation of cell projection organization GO:0031344 206 0.029
bicarbonate transport GO:0015701 7 0.029
sensory perception GO:0007600 245 0.029
locomotory behavior GO:0007626 195 0.029
oligopeptide transmembrane transport GO:0035672 4 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
fat soluble vitamin biosynthetic process GO:0042362 4 0.028
regulation of cell migration GO:0030334 219 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
gonad development GO:0008406 141 0.027
nucleotide catabolic process GO:0009166 217 0.027
nucleoside catabolic process GO:0009164 206 0.027
organic cyclic compound catabolic process GO:1901361 295 0.026
organophosphate biosynthetic process GO:0090407 122 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.026
cellular amino acid metabolic process GO:0006520 103 0.026
cellular response to lipid GO:0071396 145 0.026
carbohydrate metabolic process GO:0005975 230 0.025
positive regulation of cell death GO:0010942 224 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
purine nucleotide catabolic process GO:0006195 211 0.025
purine containing compound catabolic process GO:0072523 213 0.025
inner ear receptor cell differentiation GO:0060113 61 0.024
epidermis development GO:0008544 187 0.024
cellular ketone metabolic process GO:0042180 84 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
calcitriol biosynthetic process from calciol GO:0036378 3 0.023
nucleotide biosynthetic process GO:0009165 78 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
organophosphate catabolic process GO:0046434 232 0.023
regulation of body fluid levels GO:0050878 162 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
amino acid transport GO:0006865 61 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
regulation of protein kinase activity GO:0045859 232 0.022
blood circulation GO:0008015 195 0.022
organic hydroxy compound biosynthetic process GO:1901617 77 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
retina morphogenesis in camera type eye GO:0060042 45 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
ribonucleoside monophosphate metabolic process GO:0009161 80 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
ribonucleotide catabolic process GO:0009261 208 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
monosaccharide metabolic process GO:0005996 106 0.020
response to acid chemical GO:0001101 111 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
protein maturation GO:0051604 176 0.019
dipeptide transport GO:0042938 2 0.019
transepithelial chloride transport GO:0030321 4 0.019
divalent inorganic cation homeostasis GO:0072507 138 0.019
fluid transport GO:0042044 14 0.019
small molecule biosynthetic process GO:0044283 132 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
auditory receptor cell differentiation GO:0042491 37 0.019
male gamete generation GO:0048232 285 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
protein processing GO:0016485 163 0.019
macromolecule catabolic process GO:0009057 281 0.018
Worm
ras protein signal transduction GO:0007265 77 0.018
cytokine production GO:0001816 319 0.018
positive regulation of cell development GO:0010720 237 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
regulation of anatomical structure size GO:0090066 178 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
cellular response to lipopolysaccharide GO:0071222 77 0.018
vitamin d3 metabolic process GO:0070640 3 0.018
regulation of secretion GO:0051046 274 0.018
regulation of cellular component size GO:0032535 121 0.017
response to organonitrogen compound GO:0010243 246 0.017
positive regulation of homeostatic process GO:0032846 64 0.017
intracellular protein transport GO:0006886 204 0.017
reactive nitrogen species metabolic process GO:2001057 0 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
myeloid cell differentiation GO:0030099 233 0.017
response to inorganic substance GO:0010035 96 0.017
negative regulation of immune system process GO:0002683 209 0.017
carbohydrate homeostasis GO:0033500 128 0.017
atp metabolic process GO:0046034 75 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
vesicle organization GO:0016050 60 0.016
blood vessel morphogenesis GO:0048514 285 0.016
regulation of organelle organization GO:0033043 289 0.016
regulation of homeostatic process GO:0032844 182 0.016
hindbrain development GO:0030902 128 0.016
epithelial cell development GO:0002064 159 0.016
Mouse
pons development GO:0021548 13 0.016
metencephalon development GO:0022037 89 0.016
negative regulation of cell cycle GO:0045786 123 0.016
cellular response to external stimulus GO:0071496 88 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
response to nutrient levels GO:0031667 109 0.015
glucose homeostasis GO:0042593 128 0.015
endocytosis GO:0006897 168 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
hair cell differentiation GO:0035315 40 0.015
muscle tissue development GO:0060537 308 0.015
Mouse
mitotic cell cycle GO:0000278 195 0.015
oxidation reduction process GO:0055114 342 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
amine metabolic process GO:0009308 45 0.015
leukocyte migration GO:0050900 124 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
auditory receptor cell development GO:0060117 20 0.015
negative regulation of cell development GO:0010721 169 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
sulfur compound metabolic process GO:0006790 100 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
cellular response to cytokine stimulus GO:0071345 189 0.014
membrane organization GO:0061024 245 0.014
photoreceptor cell development GO:0042461 40 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of cytokine production GO:0001817 266 0.014
regulation of cell cycle GO:0051726 281 0.014
response to extracellular stimulus GO:0009991 127 0.014
nuclear division GO:0000280 158 0.014
pyramidal neuron development GO:0021860 8 0.014
neural retina development GO:0003407 41 0.014
c4 dicarboxylate transport GO:0015740 3 0.014
response to organic cyclic compound GO:0014070 198 0.014
regulation of hydrolase activity GO:0051336 246 0.014
striated muscle tissue development GO:0014706 293 0.014
Mouse
regulation of cellular ph reduction GO:0032847 2 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
apoptotic signaling pathway GO:0097190 306 0.014
defense response to other organism GO:0098542 197 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
cell chemotaxis GO:0060326 81 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
hexose metabolic process GO:0019318 98 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
response to pain GO:0048265 26 0.013
atp catabolic process GO:0006200 55 0.013
cell adhesion GO:0007155 329 0.013
rhythmic process GO:0048511 174 0.013
multi multicellular organism process GO:0044706 109 0.013
inflammatory response GO:0006954 244 0.013
regulation of cellular amine metabolic process GO:0033238 20 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
respiratory system development GO:0060541 190 0.013
positive regulation of nervous system development GO:0051962 221 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
glucose transport GO:0015758 56 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
rho protein signal transduction GO:0007266 32 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
endomembrane system organization GO:0010256 147 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
digestive tract development GO:0048565 190 0.012
peptide secretion GO:0002790 114 0.012
protein polymerization GO:0051258 57 0.012
defense response to bacterium GO:0042742 119 0.012
protein localization to membrane GO:0072657 108 0.012
compound eye development GO:0048749 1 0.012
ossification GO:0001503 216 0.012
lung development GO:0030324 164 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
protein catabolic process GO:0030163 221 0.012
Worm
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
acid secretion GO:0046717 33 0.012
Mouse
response to peptide hormone GO:0043434 127 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
purine ribonucleotide biosynthetic process GO:0009152 59 0.012
regulation of cell growth GO:0001558 91 0.012
regulation of neuron death GO:1901214 134 0.012
nucleoside monophosphate catabolic process GO:0009125 59 0.012
response to drug GO:0042493 75 0.012
mitochondrion organization GO:0007005 134 0.012
protein oligomerization GO:0051259 67 0.012
muscle cell differentiation GO:0042692 261 0.012
Mouse
response to oxidative stress GO:0006979 123 0.011
positive regulation of organelle organization GO:0010638 128 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
developmental maturation GO:0021700 193 0.011
calcium ion homeostasis GO:0055074 127 0.011
skeletal system development GO:0001501 356 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
amino acid transmembrane transport GO:0003333 37 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
regulation of mapk cascade GO:0043408 248 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
organelle assembly GO:0070925 177 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
transmission of nerve impulse GO:0019226 76 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
regulation of dipeptide transmembrane transport GO:2001148 2 0.011
immune effector process GO:0002252 321 0.011
forebrain development GO:0030900 302 0.011
steroid biosynthetic process GO:0006694 47 0.011
positive regulation of dipeptide transmembrane transport GO:2001150 2 0.011
monosaccharide transport GO:0015749 58 0.011
regulation of cell size GO:0008361 72 0.011
developmental programmed cell death GO:0010623 41 0.011
body fluid secretion GO:0007589 53 0.011
positive regulation of cytokine production GO:0001819 174 0.011
negative regulation of cell motility GO:2000146 61 0.011
multicellular organismal response to stress GO:0033555 62 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
dicarboxylic acid transport GO:0006835 29 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
innate immune response GO:0045087 157 0.011
tissue homeostasis GO:0001894 115 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
regulation of neuron projection development GO:0010975 169 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
muscle system process GO:0003012 141 0.010
Worm
regulation of peptide transport GO:0090087 91 0.010
Worm
positive regulation of map kinase activity GO:0043406 84 0.010
tube formation GO:0035148 140 0.010
second messenger mediated signaling GO:0019932 73 0.010
peptidyl amino acid modification GO:0018193 336 0.010
cell substrate adhesion GO:0031589 130 0.010
regulation of transferase activity GO:0051338 263 0.010
negative regulation of multi organism process GO:0043901 68 0.010
spermatid development GO:0007286 108 0.010
cellular response to nutrient levels GO:0031669 64 0.010
regulation of cellular response to stress GO:0080135 159 0.010
carbohydrate transport GO:0008643 62 0.010
organelle fission GO:0048285 170 0.010
camera type eye photoreceptor cell differentiation GO:0060219 15 0.010
glycerolipid metabolic process GO:0046486 122 0.010
lipid storage GO:0019915 36 0.010
Worm
purine nucleotide biosynthetic process GO:0006164 65 0.010
cellular lipid catabolic process GO:0044242 52 0.010
metal ion homeostasis GO:0055065 189 0.010
alpha amino acid metabolic process GO:1901605 59 0.010

Slc9a3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
musculoskeletal system disease DOID:17 0 0.025
inherited metabolic disorder DOID:655 0 0.020
disease of metabolism DOID:0014667 0 0.020
connective tissue disease DOID:65 0 0.020
bone disease DOID:0080001 0 0.020
central nervous system disease DOID:331 0 0.017
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.015