Mus musculus

11 known processes

Slfn2

schlafen 2

(Aliases: Shlf2)

Slfn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune effector process GO:0002252 321 0.536
innate immune response GO:0045087 157 0.528
defense response to other organism GO:0098542 197 0.505
defense response to virus GO:0051607 68 0.501
positive regulation of defense response GO:0031349 124 0.359
t cell differentiation GO:0030217 174 0.327
t cell proliferation GO:0042098 120 0.314
regulation of defense response GO:0031347 233 0.297
positive regulation of innate immune response GO:0045089 80 0.296
negative regulation of cell proliferation GO:0008285 296 0.283
cellular response to biotic stimulus GO:0071216 92 0.279
cytokine production GO:0001816 319 0.278
interspecies interaction between organisms GO:0044419 83 0.262
regulation of cell motility GO:2000145 236 0.257
leukocyte differentiation GO:0002521 342 0.253
reactive oxygen species metabolic process GO:0072593 84 0.239
lymphocyte differentiation GO:0030098 242 0.235
innate immune response activating signal transduction GO:0002758 50 0.230
positive regulation of apoptotic process GO:0043065 217 0.229
myeloid leukocyte differentiation GO:0002573 119 0.222
myeloid cell differentiation GO:0030099 233 0.219
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.196
t cell activation GO:0042110 289 0.193
leukocyte proliferation GO:0070661 172 0.193
myeloid cell homeostasis GO:0002262 114 0.168
toll like receptor signaling pathway GO:0002224 38 0.156
protein catabolic process GO:0030163 221 0.156
cellular homeostasis GO:0019725 240 0.151
apoptotic signaling pathway GO:0097190 306 0.149
regulation of cell migration GO:0030334 219 0.146
cellular response to cytokine stimulus GO:0071345 189 0.145
i kappab kinase nf kappab signaling GO:0007249 85 0.142
positive regulation of cellular amine metabolic process GO:0033240 5 0.139
regulation of cell activation GO:0050865 289 0.138
immune response regulating signaling pathway GO:0002764 125 0.138
actin cytoskeleton organization GO:0030036 220 0.126
regulation of leukocyte differentiation GO:1902105 159 0.124
positive regulation of cell death GO:0010942 224 0.124
sequestering of metal ion GO:0051238 19 0.124
glycosyl compound metabolic process GO:1901657 246 0.122
regulation of actin filament length GO:0030832 45 0.122
activation of innate immune response GO:0002218 56 0.120
regulation of tumor necrosis factor production GO:0032680 49 0.120
regulation of lymphocyte activation GO:0051249 240 0.119
macromolecule catabolic process GO:0009057 281 0.116
regulation of homeostatic process GO:0032844 182 0.115
positive regulation of cell activation GO:0050867 158 0.114
cell adhesion GO:0007155 329 0.112
positive regulation of programmed cell death GO:0043068 218 0.112
muscle cell differentiation GO:0042692 261 0.110
leukocyte activation involved in immune response GO:0002366 126 0.109
cellular amino acid metabolic process GO:0006520 103 0.107
activation of immune response GO:0002253 138 0.106
regulation of innate immune response GO:0045088 91 0.105
negative regulation of molecular function GO:0044092 258 0.101
adaptive immune response GO:0002250 155 0.100
viral transcription GO:0019083 3 0.096
regulation of cytokine production GO:0001817 266 0.095
regulation of protein localization GO:0032880 231 0.093
membrane organization GO:0061024 245 0.090
cellular ketone metabolic process GO:0042180 84 0.090
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.090
regulation of cellular amine metabolic process GO:0033238 20 0.089
cellular response to lipopolysaccharide GO:0071222 77 0.089
lymphocyte proliferation GO:0046651 164 0.088
regulation of t cell activation GO:0050863 170 0.088
t cell activation involved in immune response GO:0002286 43 0.087
regulation of reactive oxygen species metabolic process GO:2000377 40 0.085
positive regulation of protein modification process GO:0031401 299 0.085
neutrophil migration GO:1990266 37 0.085
calcium ion transport GO:0006816 159 0.083
regulation of cytoskeleton organization GO:0051493 122 0.083
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.082
regulation of actin filament based process GO:0032970 99 0.081
negative regulation of protein metabolic process GO:0051248 282 0.081
heterocycle catabolic process GO:0046700 280 0.078
cellular response to lipid GO:0071396 145 0.078
pattern recognition receptor signaling pathway GO:0002221 47 0.077
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.077
cytokine mediated signaling pathway GO:0019221 115 0.077
positive regulation of t cell differentiation GO:0045582 52 0.075
regulation of cellular component biogenesis GO:0044087 181 0.074
negative regulation of immune system process GO:0002683 209 0.073
regulation of secretion GO:0051046 274 0.073
positive regulation of cellular component biogenesis GO:0044089 94 0.073
amine metabolic process GO:0009308 45 0.072
cellular nitrogen compound catabolic process GO:0044270 280 0.072
gland development GO:0048732 330 0.071
positive regulation of cytokine production GO:0001819 174 0.070
cation transport GO:0006812 399 0.070
positive regulation of mapk cascade GO:0043410 170 0.069
purine ribonucleotide metabolic process GO:0009150 290 0.069
divalent metal ion transport GO:0070838 172 0.069
negative regulation of multi organism process GO:0043901 68 0.068
rho protein signal transduction GO:0007266 32 0.067
regulation of cellular catabolic process GO:0031329 242 0.067
ribonucleoside catabolic process GO:0042454 206 0.066
nucleoside catabolic process GO:0009164 206 0.065
negative regulation of viral genome replication GO:0045071 10 0.065
cytosolic calcium ion homeostasis GO:0051480 70 0.064
purine containing compound metabolic process GO:0072521 311 0.064
cellular response to molecule of bacterial origin GO:0071219 83 0.064
nucleobase containing small molecule metabolic process GO:0055086 352 0.064
regulation of cell adhesion GO:0030155 154 0.063
regulation of alpha beta t cell activation GO:0046634 53 0.063
positive regulation of lymphocyte activation GO:0051251 140 0.063
maintenance of location GO:0051235 89 0.063
glycosyl compound catabolic process GO:1901658 206 0.062
response to molecule of bacterial origin GO:0002237 143 0.062
regulation of lymphocyte differentiation GO:0045619 107 0.061
regulation of cellular ketone metabolic process GO:0010565 66 0.061
cellular amine metabolic process GO:0044106 44 0.060
inflammatory response GO:0006954 244 0.059
small gtpase mediated signal transduction GO:0007264 97 0.058
cation homeostasis GO:0055080 212 0.058
purine ribonucleoside metabolic process GO:0046128 241 0.058
nucleoside triphosphate metabolic process GO:0009141 230 0.058
positive regulation of lymphocyte proliferation GO:0050671 70 0.056
alpha beta t cell activation GO:0046631 91 0.056
guanosine containing compound metabolic process GO:1901068 144 0.056
alpha beta t cell proliferation GO:0046633 21 0.055
g protein coupled receptor signaling pathway GO:0007186 243 0.055
regulation of transferase activity GO:0051338 263 0.055
ear development GO:0043583 200 0.055
ribonucleoside triphosphate metabolic process GO:0009199 220 0.054
positive regulation of nucleotide catabolic process GO:0030813 88 0.053
cell activation involved in immune response GO:0002263 126 0.053
negative regulation of cellular protein metabolic process GO:0032269 247 0.052
negative regulation of cell migration GO:0030336 59 0.052
regulation of mapk cascade GO:0043408 248 0.052
endocytosis GO:0006897 168 0.052
negative regulation of defense response GO:0031348 77 0.052
regulation of establishment of protein localization GO:0070201 181 0.052
muscle tissue development GO:0060537 308 0.051
regulation of t helper 2 cell cytokine production GO:2000551 3 0.051
engulfment of apoptotic cell GO:0043652 3 0.051
b cell activation GO:0042113 161 0.051
positive regulation of cell motility GO:2000147 116 0.050
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.050
regulation of actin cytoskeleton organization GO:0032956 84 0.050
regulation of leukocyte proliferation GO:0070663 121 0.050
positive regulation of t cell activation GO:0050870 101 0.049
regulation of protein transport GO:0051223 163 0.049
negative regulation of immune effector process GO:0002698 55 0.049
nucleotide catabolic process GO:0009166 217 0.049
regulation of secretion by cell GO:1903530 249 0.049
regulation of t cell differentiation GO:0045580 83 0.049
cellular macromolecule catabolic process GO:0044265 206 0.049
regulation of protein complex assembly GO:0043254 83 0.048
negative regulation of viral process GO:0048525 23 0.048
cellular ion homeostasis GO:0006873 165 0.048
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.048
cellular metal ion homeostasis GO:0006875 151 0.048
regulation of organelle organization GO:0033043 289 0.047
t helper 2 cell cytokine production GO:0035745 4 0.047
response to organic cyclic compound GO:0014070 198 0.047
actin polymerization or depolymerization GO:0008154 54 0.047
regulation of inflammatory response GO:0050727 147 0.046
positive regulation of leukocyte differentiation GO:1902107 86 0.046
negative regulation of viral transcription GO:0032897 3 0.046
ribonucleoside metabolic process GO:0009119 245 0.046
regulation of ion transport GO:0043269 215 0.046
viral life cycle GO:0019058 36 0.045
purine containing compound catabolic process GO:0072523 213 0.045
positive regulation of organelle organization GO:0010638 128 0.045
purine nucleotide catabolic process GO:0006195 211 0.045
toll like receptor 7 signaling pathway GO:0034154 4 0.045
positive regulation of cellular catabolic process GO:0031331 148 0.044
positive regulation of t cell proliferation GO:0042102 52 0.044
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.043
peptidyl amino acid modification GO:0018193 336 0.043
cellular calcium ion homeostasis GO:0006874 119 0.043
regulation of cellular component size GO:0032535 121 0.043
carbohydrate derivative catabolic process GO:1901136 231 0.042
cytokine secretion GO:0050663 72 0.042
epithelial cell proliferation GO:0050673 174 0.042
cellular response to interferon alpha GO:0035457 4 0.042
regulation of multi organism process GO:0043900 111 0.042
positive regulation of apoptotic signaling pathway GO:2001235 95 0.042
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.042
negative regulation of cell motility GO:2000146 61 0.042
regulation of leukocyte mediated immunity GO:0002703 104 0.041
leukocyte migration GO:0050900 124 0.041
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.041
positive regulation of cell migration GO:0030335 109 0.040
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.040
posttranscriptional regulation of gene expression GO:0010608 155 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.040
divalent inorganic cation transport GO:0072511 178 0.040
regulation of apoptotic signaling pathway GO:2001233 197 0.039
interleukin 1 production GO:0032612 31 0.039
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.039
immune response activating signal transduction GO:0002757 116 0.039
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.039
organonitrogen compound catabolic process GO:1901565 264 0.039
thymocyte migration GO:0072679 2 0.039
cellular protein complex assembly GO:0043623 116 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
regulation of myeloid cell differentiation GO:0045637 96 0.038
cellular response to organonitrogen compound GO:0071417 145 0.038
cellular response to dna damage stimulus GO:0006974 207 0.038
regulation of toll like receptor signaling pathway GO:0034121 20 0.038
mapk cascade GO:0000165 281 0.038
cytoplasmic transport GO:0016482 234 0.038
regulation of ion homeostasis GO:2000021 64 0.038
viral genome replication GO:0019079 17 0.038
positive regulation of actin filament polymerization GO:0030838 26 0.037
actin filament polymerization GO:0030041 44 0.037
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.037
blood vessel morphogenesis GO:0048514 285 0.037
dendritic cell differentiation GO:0097028 26 0.036
peptidyl serine phosphorylation GO:0018105 74 0.036
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.036
nucleoside phosphate catabolic process GO:1901292 222 0.035
organophosphate catabolic process GO:0046434 232 0.035
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.035
calcium ion homeostasis GO:0055074 127 0.034
organelle assembly GO:0070925 177 0.034
intrinsic apoptotic signaling pathway GO:0097193 132 0.034
regulation of hormone levels GO:0010817 211 0.034
response to peptide GO:1901652 136 0.034
single organismal cell cell adhesion GO:0016337 131 0.034
positive regulation of cytokine biosynthetic process GO:0042108 40 0.033
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.033
t cell mediated immunity GO:0002456 50 0.033
positive regulation of kinase activity GO:0033674 155 0.033
ossification GO:0001503 216 0.033
negative regulation of intracellular signal transduction GO:1902532 167 0.033
regulation of protein kinase activity GO:0045859 232 0.033
regulation of alpha beta t cell proliferation GO:0046640 18 0.033
regulation of cell projection assembly GO:0060491 38 0.032
nucleoside metabolic process GO:0009116 246 0.032
antigen receptor mediated signaling pathway GO:0050851 64 0.032
cellular response to growth factor stimulus GO:0071363 197 0.032
positive regulation of protein kinase activity GO:0045860 144 0.032
regulation of leukocyte apoptotic process GO:2000106 56 0.032
regulation of viral transcription GO:0046782 3 0.032
regulation of binding GO:0051098 111 0.032
organic cyclic compound catabolic process GO:1901361 295 0.032
response to lipopolysaccharide GO:0032496 128 0.032
positive regulation of secretion by cell GO:1903532 114 0.032
interleukin 12 secretion GO:0072610 3 0.032
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.031
leukocyte homeostasis GO:0001776 79 0.031
protein polymerization GO:0051258 57 0.031
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.031
glucose transport GO:0015758 56 0.031
developmental maturation GO:0021700 193 0.031
regulation of kinase activity GO:0043549 249 0.031
aromatic compound catabolic process GO:0019439 286 0.030
positive regulation of immune effector process GO:0002699 107 0.030
regulation of actin filament polymerization GO:0030833 38 0.030
regulation of cytokine biosynthetic process GO:0042035 59 0.030
regulation of t cell receptor signaling pathway GO:0050856 21 0.030
calcium ion transport into cytosol GO:0060402 48 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.030
ripoptosome assembly involved in necroptotic process GO:1901026 6 0.030
leukocyte cell cell adhesion GO:0007159 14 0.030
interferon beta biosynthetic process GO:0045350 4 0.030
organonitrogen compound biosynthetic process GO:1901566 192 0.030
cellular protein catabolic process GO:0044257 155 0.030
neutrophil chemotaxis GO:0030593 36 0.030
purine nucleoside metabolic process GO:0042278 241 0.030
positive regulation of secretion GO:0051047 130 0.030
positive regulation of protein phosphorylation GO:0001934 242 0.030
regulation of hydrolase activity GO:0051336 246 0.030
purine ribonucleotide catabolic process GO:0009154 208 0.029
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.029
negative regulation of protein modification process GO:0031400 163 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
erk1 and erk2 cascade GO:0070371 77 0.029
regulation of lymphocyte proliferation GO:0050670 117 0.029
chemotaxis GO:0006935 247 0.028
negative regulation of lymphocyte activation GO:0051250 91 0.028
regulation of osteoblast differentiation GO:0045667 67 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
regulation of nitric oxide biosynthetic process GO:0045428 18 0.028
purine nucleoside triphosphate metabolic process GO:0009144 226 0.028
regulation of cellular response to stress GO:0080135 159 0.028
regulation of epithelial cell proliferation GO:0050678 141 0.028
jnk cascade GO:0007254 72 0.027
skeletal system development GO:0001501 356 0.027
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.027
viral gene expression GO:0019080 3 0.027
protein processing GO:0016485 163 0.027
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
regulation of immunological synapse formation GO:2000520 2 0.027
leukocyte chemotaxis GO:0030595 69 0.027
sensory organ morphogenesis GO:0090596 242 0.027
intracellular protein transport GO:0006886 204 0.027
glucose homeostasis GO:0042593 128 0.026
t cell receptor signaling pathway GO:0050852 46 0.026
negative regulation of kinase activity GO:0033673 81 0.026
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.026
viral process GO:0016032 41 0.026
extrinsic apoptotic signaling pathway GO:0097191 126 0.026
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.026
cellular response to type i interferon GO:0071357 10 0.026
negative regulation of apoptotic signaling pathway GO:2001234 104 0.026
lymphocyte activation involved in immune response GO:0002285 93 0.025
production of molecular mediator of immune response GO:0002440 103 0.025
exocytosis GO:0006887 121 0.025
ribonucleotide catabolic process GO:0009261 208 0.025
regulation of vesicle mediated transport GO:0060627 139 0.025
regulation of cell cycle process GO:0010564 160 0.025
angiogenesis GO:0001525 201 0.025
protein kinase b signaling GO:0043491 74 0.025
regulation of rho gtpase activity GO:0032319 58 0.025
macrophage differentiation GO:0030225 20 0.025
protein secretion GO:0009306 111 0.025
sequestering of calcium ion GO:0051208 18 0.025
positive regulation of inflammatory response GO:0050729 47 0.025
regulation of cytokine secretion GO:0050707 61 0.025
homotypic cell cell adhesion GO:0034109 28 0.025
leukocyte mediated immunity GO:0002443 174 0.025
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.024
granulocyte migration GO:0097530 43 0.024
regulation of purine nucleotide catabolic process GO:0033121 122 0.024
regulation of protein binding GO:0043393 60 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.024
syncytium formation by plasma membrane fusion GO:0000768 42 0.024
ras protein signal transduction GO:0007265 77 0.024
regulation of response to wounding GO:1903034 189 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
response to radiation GO:0009314 165 0.024
negative regulation of homeostatic process GO:0032845 71 0.024
cytosolic calcium ion transport GO:0060401 48 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.024
positive regulation of neutrophil migration GO:1902624 12 0.024
response to organonitrogen compound GO:0010243 246 0.024
cell substrate adhesion GO:0031589 130 0.024
divalent inorganic cation homeostasis GO:0072507 138 0.024
regulation of t cell proliferation GO:0042129 92 0.024
mammary gland epithelium development GO:0061180 65 0.024
lipid localization GO:0010876 126 0.024
glycoprotein metabolic process GO:0009100 116 0.023
positive regulation of gtpase activity GO:0043547 85 0.023
nucleotide metabolic process GO:0009117 332 0.023
regulation of ossification GO:0030278 112 0.023
alpha beta t cell activation involved in immune response GO:0002287 31 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
protein oligomerization GO:0051259 67 0.023
homeostasis of number of cells GO:0048872 210 0.023
b cell activation involved in immune response GO:0002312 50 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
regulation of map kinase activity GO:0043405 120 0.022
germ cell development GO:0007281 185 0.022
positive regulation of nucleoside metabolic process GO:0045979 91 0.022
telencephalon development GO:0021537 186 0.022
regulation of cell cycle GO:0051726 281 0.022
mitotic cell cycle process GO:1903047 159 0.022
positive regulation of monocyte chemotaxis GO:0090026 2 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
positive regulation of response to cytokine stimulus GO:0060760 11 0.022
regulation of protein secretion GO:0050708 82 0.022
regulation of nucleoside metabolic process GO:0009118 130 0.022
tumor necrosis factor production GO:0032640 50 0.022
granulocyte chemotaxis GO:0071621 39 0.022
myeloid leukocyte activation GO:0002274 83 0.022
leukocyte apoptotic process GO:0071887 71 0.022
t helper 17 cell lineage commitment GO:0072540 4 0.022
positive regulation of hydrolase activity GO:0051345 148 0.021
positive regulation of transferase activity GO:0051347 167 0.021
pallium development GO:0021543 120 0.021
digestive system development GO:0055123 200 0.021
positive regulation of cell development GO:0010720 237 0.021
lymphocyte migration GO:0072676 26 0.021
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
response to acid chemical GO:0001101 111 0.021
erythrocyte differentiation GO:0030218 88 0.021
response to type i interferon GO:0034340 12 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.021
molting cycle GO:0042303 90 0.020
immunoglobulin mediated immune response GO:0016064 69 0.020
extracellular structure organization GO:0043062 148 0.020
cell type specific apoptotic process GO:0097285 268 0.020
regulation of lipid metabolic process GO:0019216 118 0.020
cellular chemical homeostasis GO:0055082 215 0.020
carbohydrate metabolic process GO:0005975 230 0.020
interferon gamma production GO:0032609 67 0.020
cerebral cortex development GO:0021987 86 0.020
regulation of actin polymerization or depolymerization GO:0008064 45 0.020
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.020
regulation of striated muscle cell differentiation GO:0051153 81 0.020
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.020
protein ubiquitination GO:0016567 171 0.020
fat cell differentiation GO:0045444 160 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.020
t cell migration GO:0072678 19 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
positive regulation of response to wounding GO:1903036 66 0.020
protein localization to organelle GO:0033365 185 0.019
muscle cell development GO:0055001 133 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.019
regulation of protein catabolic process GO:0042176 108 0.019
substrate dependent cell migration cell extension GO:0006930 4 0.019
neuron projection guidance GO:0097485 141 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
negative regulation of cytokine production GO:0001818 84 0.019
hormone secretion GO:0046879 128 0.019
regulation of defense response to virus by host GO:0050691 8 0.019
peptidyl serine modification GO:0018209 83 0.019
cell recognition GO:0008037 83 0.019
regulation of membrane potential GO:0042391 192 0.019
regulation of proteolysis GO:0030162 164 0.019
cerebral cortex cell migration GO:0021795 44 0.019
membrane fusion GO:0061025 38 0.019
response to transforming growth factor beta GO:0071559 88 0.019
type i interferon signaling pathway GO:0060337 10 0.019
microglia development GO:0014005 2 0.019
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.019
single organism cell adhesion GO:0098602 156 0.019
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
monosaccharide transport GO:0015749 58 0.018
cellular extravasation GO:0045123 17 0.018
negative regulation of macrophage apoptotic process GO:2000110 3 0.018
skin development GO:0043588 220 0.018
cellular lipid metabolic process GO:0044255 323 0.018
positive regulation of leukocyte proliferation GO:0070665 73 0.018
carbohydrate transport GO:0008643 62 0.018
regulation of metal ion transport GO:0010959 106 0.018
negative regulation of cell activation GO:0050866 111 0.018
regulation of rho protein signal transduction GO:0035023 71 0.018
negative regulation of binding GO:0051100 39 0.018
mitotic cell cycle GO:0000278 195 0.018
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
t helper cell differentiation GO:0042093 28 0.018
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.018
t cell differentiation in thymus GO:0033077 77 0.017
extracellular matrix organization GO:0030198 147 0.017
organ growth GO:0035265 117 0.017
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.017
myeloid dendritic cell activation GO:0001773 25 0.017
regulation of t cell mediated immunity GO:0002709 34 0.017
positive regulation of gtp catabolic process GO:0033126 85 0.017
negative regulation of interferon beta biosynthetic process GO:0045358 1 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
positive regulation of neutrophil chemotaxis GO:0090023 12 0.017
reactive nitrogen species metabolic process GO:2001057 0 0.017
positive regulation of rho gtpase activity GO:0032321 41 0.017
cd4 positive alpha beta t cell activation GO:0035710 45 0.017
cellular divalent inorganic cation homeostasis GO:0072503 127 0.017
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.017
peptide secretion GO:0002790 114 0.017
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
regulation of intracellular transport GO:0032386 159 0.017
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
cytokine biosynthetic process GO:0042089 68 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
release of sequestered calcium ion into cytosol GO:0051209 42 0.016
negative regulation of secretion by cell GO:1903531 54 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
gliogenesis GO:0042063 141 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
positive regulation of cell projection organization GO:0031346 95 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
cytokine metabolic process GO:0042107 71 0.016
gtp catabolic process GO:0006184 143 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
actin filament organization GO:0007015 113 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.016
multi multicellular organism process GO:0044706 109 0.016
type i interferon production GO:0032606 29 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.016
negative regulation of protein transport GO:0051224 46 0.016
cytokine production involved in immune response GO:0002367 34 0.016
protein maturation GO:0051604 176 0.016
response to growth factor GO:0070848 198 0.015
cell adhesion mediated by integrin GO:0033627 18 0.015
pole plasm assembly GO:0007315 2 0.015
antigen processing and presentation of peptide antigen GO:0048002 29 0.015
negative regulation of secretion GO:0051048 61 0.015
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.015
positive regulation of homeostatic process GO:0032846 64 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.015
skeletal muscle organ development GO:0060538 163 0.015
stress activated protein kinase signaling cascade GO:0031098 81 0.015
positive regulation of chemotaxis GO:0050921 38 0.015
regulation of system process GO:0044057 200 0.015
positive regulation of nervous system development GO:0051962 221 0.015

Slfn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.021
disease of anatomical entity DOID:7 0 0.021
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016