Mus musculus

0 known processes

Slfn4

schlafen 4

(Aliases: AI450778)

Slfn4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
defense response to other organism GO:0098542 197 0.936
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.862
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.841
negative regulation of multi organism process GO:0043901 68 0.790
interspecies interaction between organisms GO:0044419 83 0.751
negative regulation of viral genome replication GO:0045071 10 0.726
immune effector process GO:0002252 321 0.713
response to molecule of bacterial origin GO:0002237 143 0.660
viral process GO:0016032 41 0.655
granulocyte chemotaxis GO:0071621 39 0.607
regulation of multi organism process GO:0043900 111 0.607
keratinocyte migration GO:0051546 3 0.551
positive regulation of defense response GO:0031349 124 0.532
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.530
regulation of cell activation GO:0050865 289 0.469
myeloid leukocyte migration GO:0097529 57 0.469
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.454
positive regulation of apoptotic process GO:0043065 217 0.439
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.437
positive regulation of macrophage chemotaxis GO:0010759 5 0.395
i kappab kinase nf kappab signaling GO:0007249 85 0.392
positive regulation of cytokine production GO:0001819 174 0.383
interaction with symbiont GO:0051702 14 0.374
detection of fungus GO:0016046 2 0.373
regulation of cell motility GO:2000145 236 0.370
neutrophil migration GO:1990266 37 0.364
cytokine production GO:0001816 319 0.354
regulation of cytokine production GO:0001817 266 0.350
innate immune response GO:0045087 157 0.339
activation of innate immune response GO:0002218 56 0.330
defense response to virus GO:0051607 68 0.320
cellular response to molecule of bacterial origin GO:0071219 83 0.316
defense response to bacterium GO:0042742 119 0.315
innate immune response activating signal transduction GO:0002758 50 0.312
cellular response to cytokine stimulus GO:0071345 189 0.308
regulation of defense response GO:0031347 233 0.305
disruption by host of symbiont cells GO:0051852 11 0.291
cellular response to lipopolysaccharide GO:0071222 77 0.290
chemotaxis GO:0006935 247 0.280
negative regulation of cell proliferation GO:0008285 296 0.273
Mouse
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.241
leukocyte chemotaxis GO:0030595 69 0.238
leukocyte migration GO:0050900 124 0.232
granulocyte migration GO:0097530 43 0.231
pattern recognition receptor signaling pathway GO:0002221 47 0.225
regulation of homeostatic process GO:0032844 182 0.222
defense response to gram positive bacterium GO:0050830 50 0.221
neutrophil chemotaxis GO:0030593 36 0.214
negative regulation of immune system process GO:0002683 209 0.213
positive regulation of neutrophil chemotaxis GO:0090023 12 0.212
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.211
viral genome replication GO:0019079 17 0.210
second messenger mediated signaling GO:0019932 73 0.209
positive regulation of cell death GO:0010942 224 0.208
cellular response to biotic stimulus GO:0071216 92 0.196
neutrophil mediated immunity GO:0002446 19 0.196
wound healing GO:0042060 157 0.189
regulation of innate immune response GO:0045088 91 0.188
immune response regulating signaling pathway GO:0002764 125 0.183
negative regulation of viral process GO:0048525 23 0.181
regulation of chemokine secretion GO:0090196 4 0.171
negative regulation of molecular function GO:0044092 258 0.171
macromolecule catabolic process GO:0009057 281 0.171
myeloid leukocyte differentiation GO:0002573 119 0.170
activation of immune response GO:0002253 138 0.165
reactive oxygen species metabolic process GO:0072593 84 0.165
myeloid leukocyte mediated immunity GO:0002444 42 0.155
leukocyte mediated immunity GO:0002443 174 0.151
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.150
immune response activating signal transduction GO:0002757 116 0.150
regulation of response to wounding GO:1903034 189 0.148
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.147
leukocyte activation involved in immune response GO:0002366 126 0.145
killing by host of symbiont cells GO:0051873 11 0.144
regulation of lymphocyte activation GO:0051249 240 0.143
neutrophil mediated killing of symbiont cell GO:0070943 8 0.139
inflammatory response GO:0006954 244 0.136
ossification GO:0001503 216 0.135
cell chemotaxis GO:0060326 81 0.135
regulation of chemokine production GO:0032642 30 0.133
detection of biotic stimulus GO:0009595 10 0.131
organonitrogen compound biosynthetic process GO:1901566 192 0.129
positive regulation of macrophage activation GO:0043032 10 0.129
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.128
negative regulation of cellular component organization GO:0051129 194 0.122
cytokine mediated signaling pathway GO:0019221 115 0.120
regulation of lymphocyte differentiation GO:0045619 107 0.119
cellular response to lipid GO:0071396 145 0.118
eosinophil activation involved in immune response GO:0002278 1 0.118
t helper 17 cell chemotaxis GO:0035705 1 0.117
negative regulation of lymphocyte activation GO:0051250 91 0.115
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.114
cytokine secretion GO:0050663 72 0.114
positive regulation of immunological synapse formation GO:2000522 1 0.110
neutrophil mediated killing of fungus GO:0070947 3 0.109
positive regulation of granulocyte chemotaxis GO:0071624 12 0.108
t cell proliferation GO:0042098 120 0.107
regulation of cell migration GO:0030334 219 0.106
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.104
cell activation involved in immune response GO:0002263 126 0.103
regulation of apoptotic signaling pathway GO:2001233 197 0.102
myeloid cell differentiation GO:0030099 233 0.102
regulation of protein transport GO:0051223 163 0.102
regulation of leukocyte mediated immunity GO:0002703 104 0.101
regulation of viral genome replication GO:0045069 13 0.101
viral life cycle GO:0019058 36 0.100
apoptotic signaling pathway GO:0097190 306 0.099
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.098
leukocyte cell cell adhesion GO:0007159 14 0.098
regulation of hematopoietic stem cell proliferation GO:1902033 3 0.093
modification of morphology or physiology of other organism GO:0035821 18 0.091
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.091
positive regulation of protein phosphorylation GO:0001934 242 0.089
nucleoside phosphate metabolic process GO:0006753 338 0.089
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.088
regulation of cellular response to stress GO:0080135 159 0.088
regulation of map kinase activity GO:0043405 120 0.088
regulation of macrophage chemotaxis GO:0010758 8 0.087
positive regulation of chemokine secretion GO:0090197 4 0.085
adaptive immune response GO:0002250 155 0.085
positive regulation of monocyte chemotaxis GO:0090026 2 0.084
positive regulation of immune effector process GO:0002699 107 0.084
positive regulation of chemokine production GO:0032722 22 0.083
fat cell differentiation GO:0045444 160 0.083
positive regulation of programmed cell death GO:0043068 218 0.082
positive regulation of apoptotic signaling pathway GO:2001235 95 0.081
positive regulation of chemotaxis GO:0050921 38 0.081
cell killing GO:0001906 67 0.081
t cell activation GO:0042110 289 0.080
homeostasis of number of cells GO:0048872 210 0.080
regulation of leukocyte proliferation GO:0070663 121 0.080
regulation of ion homeostasis GO:2000021 64 0.079
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.078
neutrophil mediated cytotoxicity GO:0070942 8 0.078
regulation of t cell activation GO:0050863 170 0.078
positive regulation of cell migration GO:0030335 109 0.077
leukocyte proliferation GO:0070661 172 0.077
cytosolic calcium ion transport GO:0060401 48 0.076
positive regulation of cellular amine metabolic process GO:0033240 5 0.075
regulation of reactive oxygen species metabolic process GO:2000377 40 0.074
regulation of toll like receptor signaling pathway GO:0034121 20 0.073
positive regulation of innate immune response GO:0045089 80 0.073
regulation of t helper 2 cell cytokine production GO:2000551 3 0.073
tissue remodeling GO:0048771 102 0.072
negative regulation of cytokine production GO:0001818 84 0.072
negative regulation of cellular protein metabolic process GO:0032269 247 0.071
protein secretion GO:0009306 111 0.071
endocytosis GO:0006897 168 0.070
negative regulation of protein metabolic process GO:0051248 282 0.070
regulation of establishment of protein localization GO:0070201 181 0.069
response to acid chemical GO:0001101 111 0.069
reactive nitrogen species metabolic process GO:2001057 0 0.069
calcium mediated signaling GO:0019722 46 0.068
inflammatory response to wounding GO:0090594 4 0.068
peptidyl amino acid modification GO:0018193 336 0.067
dna metabolic process GO:0006259 303 0.067
amide transport GO:0042886 138 0.067
positive regulation of cell motility GO:2000147 116 0.066
lymphocyte proliferation GO:0046651 164 0.066
regulation of secretion GO:0051046 274 0.065
positive regulation of t cell extravasation GO:2000409 2 0.065
regulation of protein localization GO:0032880 231 0.064
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.064
leukocyte migration involved in inflammatory response GO:0002523 7 0.063
interferon gamma production GO:0032609 67 0.063
regulation of proteolysis GO:0030162 164 0.063
negative regulation of chemokine production GO:0032682 4 0.063
protein catabolic process GO:0030163 221 0.062
regulation of stress activated mapk cascade GO:0032872 69 0.062
macrophage chemotaxis GO:0048246 14 0.061
leukocyte homeostasis GO:0001776 79 0.060
antimicrobial peptide secretion GO:0002776 1 0.060
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.060
regulation of neutrophil mediated killing of bacterium GO:0070950 1 0.060
leukocyte differentiation GO:0002521 342 0.059
jnk cascade GO:0007254 72 0.059
release of sequestered calcium ion into cytosol GO:0051209 42 0.058
regulation of neutrophil mediated killing of fungus GO:0070953 1 0.058
antibacterial peptide biosynthetic process GO:0002780 2 0.058
t cell extravasation GO:0072683 4 0.057
glycosyl compound metabolic process GO:1901657 246 0.057
myeloid cell activation involved in immune response GO:0002275 34 0.056
amino sugar catabolic process GO:0046348 1 0.056
lymphocyte activation involved in immune response GO:0002285 93 0.055
wound healing involved in inflammatory response GO:0002246 4 0.055
carbohydrate derivative biosynthetic process GO:1901137 183 0.055
positive regulation of secretion by cell GO:1903532 114 0.055
interaction with host GO:0051701 22 0.055
cellular amino acid metabolic process GO:0006520 103 0.055
cytokine biosynthetic process GO:0042089 68 0.054
ameboidal type cell migration GO:0001667 128 0.054
organophosphate biosynthetic process GO:0090407 122 0.054
positive regulation of protein kinase activity GO:0045860 144 0.053
negative regulation of synapse assembly GO:0051964 3 0.053
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.053
leukocyte mediated cytotoxicity GO:0001909 62 0.053
cellular amine metabolic process GO:0044106 44 0.053
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.053
b cell homeostasis GO:0001782 34 0.052
myeloid cell homeostasis GO:0002262 114 0.052
positive regulation of inflammatory response GO:0050729 47 0.052
mapk cascade GO:0000165 281 0.052
regulation of intracellular transport GO:0032386 159 0.052
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.052
regulation of type 2 immune response GO:0002828 18 0.051
regulation of defense response to bacterium GO:1900424 3 0.051
regulation of exocytosis GO:0017157 61 0.051
organic cyclic compound catabolic process GO:1901361 295 0.050
germ cell development GO:0007281 185 0.050
membrane organization GO:0061024 245 0.050
regulation of interferon gamma production GO:0032649 57 0.050
acute inflammatory response GO:0002526 41 0.050
regulation of t cell differentiation GO:0045580 83 0.050
regulation of jnk cascade GO:0046328 62 0.049
phagocytosis GO:0006909 66 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
divalent inorganic cation homeostasis GO:0072507 138 0.048
positive regulation of response to wounding GO:1903036 66 0.048
positive regulation of leukocyte differentiation GO:1902107 86 0.047
regulation of cytokine biosynthetic process GO:0042035 59 0.047
negative regulation of toll like receptor 2 signaling pathway GO:0034136 3 0.047
regulation of ossification GO:0030278 112 0.047
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.046
positive regulation of homeostatic process GO:0032846 64 0.046
leukocyte aggregation GO:0070486 1 0.046
response to radiation GO:0009314 165 0.046
zymogen activation GO:0031638 41 0.045
positive regulation of cell activation GO:0050867 158 0.045
response to molecule of fungal origin GO:0002238 4 0.045
regulation of regulated secretory pathway GO:1903305 20 0.045
purine containing compound metabolic process GO:0072521 311 0.045
amine metabolic process GO:0009308 45 0.045
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.045
cell adhesion GO:0007155 329 0.044
positive regulation of lymphocyte activation GO:0051251 140 0.044
nucleocytoplasmic transport GO:0006913 139 0.044
lysosome localization GO:0032418 20 0.043
cellular nitrogen compound catabolic process GO:0044270 280 0.043
eosinophil degranulation GO:0043308 1 0.043
interleukin 18 mediated signaling pathway GO:0035655 2 0.043
negative regulation of growth GO:0045926 99 0.043
negative regulation of cell activation GO:0050866 111 0.043
detection of yeast GO:0001879 2 0.043
regulated secretory pathway GO:0045055 32 0.043
cellular extravasation GO:0045123 17 0.043
cytoplasmic transport GO:0016482 234 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.042
response to lipopolysaccharide GO:0032496 128 0.042
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.042
cellular response to molecule of fungal origin GO:0071226 2 0.042
regulation of mapk cascade GO:0043408 248 0.042
regulation of cytokine secretion GO:0050707 61 0.042
chemokine secretion GO:0090195 5 0.041
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.041
myeloid leukocyte activation GO:0002274 83 0.041
t cell differentiation GO:0030217 174 0.040
chemokine production GO:0032602 34 0.040
regulation of neutrophil chemotaxis GO:0090022 14 0.040
extrinsic apoptotic signaling pathway GO:0097191 126 0.040
antimicrobial peptide biosynthetic process GO:0002777 2 0.040
positive regulation of t cell activation GO:0050870 101 0.040
sequestering of metal ion GO:0051238 19 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.040
positive regulation of map kinase activity GO:0043406 84 0.039
regulation of neutrophil migration GO:1902622 14 0.039
nitrogen compound transport GO:0071705 271 0.039
regulation of wound healing GO:0061041 40 0.039
response to transforming growth factor beta GO:0071559 88 0.039
protein processing GO:0016485 163 0.039
cation homeostasis GO:0055080 212 0.038
natural killer cell activation GO:0030101 44 0.038
positive regulation of intracellular transport GO:0032388 70 0.038
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.038
regulation of osteoblast differentiation GO:0045667 67 0.038
regulation of neuron death GO:1901214 134 0.038
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.037
t cell activation involved in immune response GO:0002286 43 0.037
g protein coupled receptor signaling pathway GO:0007186 243 0.037
killing of cells of other organism GO:0031640 13 0.037
regulation of t cell costimulation GO:2000523 2 0.037
positive regulation of interferon gamma production GO:0032729 39 0.037
cytokine metabolic process GO:0042107 71 0.037
stress activated protein kinase signaling cascade GO:0031098 81 0.037
detection of stimulus GO:0051606 84 0.037
response to organic cyclic compound GO:0014070 198 0.037
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.036
connective tissue development GO:0061448 179 0.036
microglial cell activation involved in immune response GO:0002282 1 0.036
cellular calcium ion homeostasis GO:0006874 119 0.036
regulation of ion transport GO:0043269 215 0.036
reactive oxygen species biosynthetic process GO:1903409 8 0.035
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.035
peptide transport GO:0015833 133 0.035
t helper 2 cell cytokine production GO:0035745 4 0.035
chromatin modification GO:0016568 187 0.035
muscle cell differentiation GO:0042692 261 0.035
engulfment of apoptotic cell GO:0043652 3 0.035
positive regulation of lymphocyte proliferation GO:0050671 70 0.035
regulation of hemostasis GO:1900046 28 0.035
regulation of granulocyte chemotaxis GO:0071622 17 0.035
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.034
transmission of nerve impulse GO:0019226 76 0.034
regulation of t cell extravasation GO:2000407 3 0.034
protein import into nucleus GO:0006606 95 0.034
stem cell development GO:0048864 219 0.034
protein localization to organelle GO:0033365 185 0.034
regulation of vascular endothelial growth factor production GO:0010574 13 0.034
positive regulation of proteolysis GO:0045862 85 0.034
exocytosis GO:0006887 121 0.034
protein kinase b signaling GO:0043491 74 0.034
nucleoside phosphate biosynthetic process GO:1901293 79 0.034
negative regulation of phosphate metabolic process GO:0045936 184 0.034
response to organonitrogen compound GO:0010243 246 0.034
dendritic cell differentiation GO:0097028 26 0.034
forebrain development GO:0030900 302 0.034
interleukin 33 mediated signaling pathway GO:0038172 1 0.034
nucleotide biosynthetic process GO:0009165 78 0.033
fertilization GO:0009566 127 0.033
activation of mapk activity GO:0000187 59 0.033
regulation of cellular component biogenesis GO:0044087 181 0.033
glial cell differentiation GO:0010001 131 0.033
positive regulation of hydrolase activity GO:0051345 148 0.033
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.033
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.033
regulation of alpha beta t cell activation GO:0046634 53 0.033
establishment of protein localization to organelle GO:0072594 118 0.033
cytosolic calcium ion homeostasis GO:0051480 70 0.033
regulation of lymphocyte proliferation GO:0050670 117 0.032
b cell mediated immunity GO:0019724 71 0.032
cellular ion homeostasis GO:0006873 165 0.032
response to oxidative stress GO:0006979 123 0.032
activation of jun kinase activity GO:0007257 15 0.032
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.032
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.032
regulation of secretion by cell GO:1903530 249 0.032
mature dendritic cell differentiation GO:0097029 3 0.032
single organismal cell cell adhesion GO:0016337 131 0.032
neutrophil mediated killing of bacterium GO:0070944 6 0.032
cellular homeostasis GO:0019725 240 0.032
regulation of cysteine type endopeptidase activity GO:2000116 65 0.032
gland development GO:0048732 330 0.032
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.032
striated muscle tissue development GO:0014706 293 0.032
positive regulation of neutrophil mediated killing of fungus GO:0070965 1 0.031
production of molecular mediator of immune response GO:0002440 103 0.031
epithelial tube morphogenesis GO:0060562 303 0.031
lymphocyte differentiation GO:0030098 242 0.031
leukocyte apoptotic process GO:0071887 71 0.031
response to hyperoxia GO:0055093 2 0.031
regulation of macrophage activation GO:0043030 17 0.031
helper t cell chemotaxis GO:0035704 1 0.030
regulation of protein serine threonine kinase activity GO:0071900 157 0.030
regulation of endopeptidase activity GO:0052548 89 0.030
regulation of chemotaxis GO:0050920 53 0.030
regulation of neutrophil mediated cytotoxicity GO:0070948 2 0.030
regulation of fat cell differentiation GO:0045598 81 0.030
intrinsic apoptotic signaling pathway GO:0097193 132 0.030
alpha beta t cell differentiation GO:0046632 69 0.030
digestive tract development GO:0048565 190 0.029
regulation of leukocyte apoptotic process GO:2000106 56 0.029
intracellular protein transport GO:0006886 204 0.029
activation of mapk activity involved in innate immune response GO:0035419 2 0.029
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.029
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.029
leukocyte degranulation GO:0043299 27 0.029
regulation of tumor necrosis factor production GO:0032680 49 0.029
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.029
macrophage differentiation GO:0030225 20 0.029
maintenance of location GO:0051235 89 0.029
regulation of dendritic cell chemotaxis GO:2000508 1 0.029
cellular macromolecule catabolic process GO:0044265 206 0.029
positive regulation of protein transport GO:0051222 93 0.029
positive regulation of behavior GO:0048520 40 0.028
calcium ion homeostasis GO:0055074 127 0.028
aromatic compound catabolic process GO:0019439 286 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
regulation of glial cell differentiation GO:0045685 41 0.028
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.028
positive regulation of ossification GO:0045778 47 0.028
divalent inorganic cation transport GO:0072511 178 0.027
negative regulation of t cell activation GO:0050868 65 0.027
regulation of binding GO:0051098 111 0.027
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.027
carbohydrate metabolic process GO:0005975 230 0.027
lymphocyte mediated immunity GO:0002449 139 0.027
epithelial cell proliferation GO:0050673 174 0.027
cellular divalent inorganic cation homeostasis GO:0072503 127 0.027
nuclear import GO:0051170 95 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.027
antibacterial humoral response GO:0019731 8 0.027
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.027
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.027
divalent metal ion transport GO:0070838 172 0.027
negative regulation of eosinophil degranulation GO:0043310 1 0.027
regulation of membrane potential GO:0042391 192 0.027
negative regulation of macrophage chemotaxis GO:0010760 1 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.026
protein import GO:0017038 101 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
skeletal muscle organ development GO:0060538 163 0.026
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.026
regulation of protein secretion GO:0050708 82 0.026
negative regulation of protein processing GO:0010955 79 0.026
signal transduction in absence of ligand GO:0038034 55 0.026
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.026
growth involved in symbiotic interaction GO:0044110 23 0.026
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.026
positive regulation of lymphocyte differentiation GO:0045621 61 0.026
neuron death GO:0070997 154 0.025
calcium ion transport GO:0006816 159 0.025
positive regulation of transferase activity GO:0051347 167 0.025
negative regulation of nervous system development GO:0051961 156 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
negative regulation of homeostatic process GO:0032845 71 0.025
carbohydrate derivative catabolic process GO:1901136 231 0.025
regulation of adaptive immune response GO:0002819 90 0.025
positive regulation of fat cell differentiation GO:0045600 32 0.025
purine containing compound biosynthetic process GO:0072522 70 0.025
regulation of translation GO:0006417 71 0.025
sequestering of calcium ion GO:0051208 18 0.025
protein targeting GO:0006605 143 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
single organism nuclear import GO:1902593 95 0.024
complement receptor mediated signaling pathway GO:0002430 1 0.024
alpha beta t cell proliferation GO:0046633 21 0.024
regulation of chromosome organization GO:0033044 83 0.024
cation transport GO:0006812 399 0.024
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.024
regulation of protein complex assembly GO:0043254 83 0.024
regulation of response to biotic stimulus GO:0002831 38 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
myeloid cell apoptotic process GO:0033028 22 0.024
antimicrobial peptide production GO:0002775 2 0.024
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.024
circulatory system process GO:0003013 197 0.024
regulation of t cell proliferation GO:0042129 92 0.024
nuclear transport GO:0051169 139 0.023
metal ion homeostasis GO:0055065 189 0.023
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.023
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
regulation of jun kinase activity GO:0043506 40 0.023
female gamete generation GO:0007292 74 0.023
positive regulation of phagocytosis GO:0050766 26 0.023
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.023
positive regulation of kinase activity GO:0033674 155 0.023
extracellular structure organization GO:0043062 148 0.023
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 3 0.023
detection of molecule of bacterial origin GO:0032490 2 0.023
positive regulation of secretion GO:0051047 130 0.023
negative regulation of kinase activity GO:0033673 81 0.023
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.023
blood vessel morphogenesis GO:0048514 285 0.023
regulation of cytoplasmic transport GO:1903649 112 0.022
cell maturation GO:0048469 127 0.022
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.022
positive regulation of type 2 immune response GO:0002830 9 0.022
positive regulation of endopeptidase activity GO:0010950 43 0.022
detection of other organism GO:0098543 8 0.022
carbohydrate transport GO:0008643 62 0.022
regulation of protein catabolic process GO:0042176 108 0.022
response to ionizing radiation GO:0010212 42 0.022
positive regulation of monocyte extravasation GO:2000439 1 0.022
positive regulation of neutrophil migration GO:1902624 12 0.022
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.022
regulation of t helper 1 type immune response GO:0002825 17 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
stem cell differentiation GO:0048863 268 0.022
superoxide metabolic process GO:0006801 27 0.022
regulation of homotypic cell cell adhesion GO:0034110 13 0.022
heterocycle catabolic process GO:0046700 280 0.022
nucleotide metabolic process GO:0009117 332 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
pallium development GO:0021543 120 0.021
digestive system development GO:0055123 200 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
glucose transport GO:0015758 56 0.021
positive regulation of cytoplasmic transport GO:1903651 40 0.021
cell recognition GO:0008037 83 0.021
placenta development GO:0001890 140 0.021
activation of cysteine type endopeptidase activity GO:0097202 27 0.021
negative regulation of leukocyte degranulation GO:0043301 7 0.021
vascular endothelial growth factor production GO:0010573 13 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
negative regulation of macrophage apoptotic process GO:2000110 3 0.021
positive regulation of t cell differentiation GO:0045582 52 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
stress activated mapk cascade GO:0051403 80 0.021

Slfn4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.130
cancer DOID:162 0 0.117
organ system cancer DOID:0050686 0 0.117
respiratory system disease DOID:1579 0 0.079
disease of anatomical entity DOID:7 0 0.079
immune system disease DOID:2914 0 0.030