Mus musculus

62 known processes

Slit3

slit homolog 3 (Drosophila)

(Aliases: Slil2)

Slit3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
roundabout signaling pathway GO:0035385 0 1.000
Human Fly
dorsal ventral axon guidance GO:0033563 3 1.000
Mouse Worm
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.999
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.995
regulation of negative chemotaxis GO:0050923 1 0.995
Fly
cardioblast migration GO:0003260 1 0.995
cell migration to the midline involved in heart development GO:0003318 1 0.991
formation of organ boundary GO:0010160 1 0.962
Fly
negative regulation of chemotaxis GO:0050922 11 0.959
Worm
olfactory bulb interneuron differentiation GO:0021889 12 0.951
mesodermal cell migration GO:0008078 4 0.943
Fly
negative regulation of behavior GO:0048521 14 0.943
Worm
chemokine mediated signaling pathway GO:0070098 17 0.938
Human
negative chemotaxis GO:0050919 14 0.930
Human Mouse Fly
cell cell adhesion GO:0098609 41 0.918
mammary duct terminal end bud growth GO:0060763 5 0.913
Mouse
heart morphogenesis GO:0003007 178 0.913
Fly
olfactory bulb development GO:0021772 30 0.909
Mouse
epithelial tube morphogenesis GO:0060562 303 0.906
Mouse
negative regulation of endothelial cell migration GO:0010596 4 0.896
olfactory bulb interneuron development GO:0021891 7 0.887
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.860
cell migration involved in heart formation GO:0060974 1 0.849
smooth muscle cell chemotaxis GO:0071670 2 0.841
substrate dependent cell migration GO:0006929 18 0.829
central nervous system projection neuron axonogenesis GO:0021952 21 0.818
Zebrafish
olfactory lobe development GO:0021988 32 0.817
Mouse
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.813
Zebrafish Mouse Worm
negative regulation of axon guidance GO:1902668 8 0.811
Worm
development of primary female sexual characteristics GO:0046545 73 0.789
Human
mammary gland duct morphogenesis GO:0060603 38 0.769
Mouse
negative regulation of axon extension GO:0030517 19 0.759
Zebrafish Mouse Worm
cell adhesion GO:0007155 329 0.758
Mouse Fly
regulation of chemotaxis GO:0050920 53 0.753
Worm Fly
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.743
retinal ganglion cell axon guidance GO:0031290 18 0.731
Mouse
neuron projection guidance GO:0097485 141 0.728
regulation of monocyte chemotaxis GO:0090025 3 0.723
regulation of cell migration GO:0030334 219 0.716
Fly
tissue migration GO:0090130 68 0.715
Fly
nucleus localization GO:0051647 20 0.705
Mouse
regulation of axon extension GO:0030516 43 0.702
Zebrafish Mouse Worm
developmental growth involved in morphogenesis GO:0060560 138 0.701
Human Zebrafish Mouse Worm
formation of anatomical boundary GO:0048859 6 0.684
Fly
anterior posterior axon guidance GO:0033564 5 0.673
negative regulation of leukocyte differentiation GO:1902106 51 0.668
Mouse
negative regulation of synapse assembly GO:0051964 3 0.664
regulation of neuron projection development GO:0010975 169 0.662
Zebrafish Mouse Worm
cerebral cortex tangential migration GO:0021800 7 0.654
mesonephros development GO:0001823 97 0.651
negative regulation of cell growth GO:0030308 44 0.649
Human Zebrafish Mouse Worm
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.637
cell recognition GO:0008037 83 0.634
Fly
commissural neuron axon guidance GO:0071679 8 0.631
response to growth factor GO:0070848 198 0.625
positive regulation of chemotaxis GO:0050921 38 0.624
Fly
single organism cell adhesion GO:0098602 156 0.617
Mouse Fly
kidney development GO:0001822 213 0.616
Mouse
mesonephric tubule development GO:0072164 94 0.615
axon guidance GO:0007411 141 0.610
forebrain development GO:0030900 302 0.594
Mouse
urogenital system development GO:0001655 261 0.590
Mouse
positive chemotaxis GO:0050918 18 0.567
cell fate commitment GO:0045165 210 0.562
Fly
mammary gland morphogenesis GO:0060443 54 0.551
Mouse
regulation of cell adhesion GO:0030155 154 0.545
Fly
neuron projection extension GO:1990138 64 0.545
Human Zebrafish Mouse Worm
negative regulation of cell migration GO:0030336 59 0.537
female gonad development GO:0008585 71 0.533
Human
digestive tract morphogenesis GO:0048546 147 0.532
Fly
embryonic heart tube development GO:0035050 65 0.531
Fly
regulation of cell size GO:0008361 72 0.529
Zebrafish Mouse Worm
osteoclast differentiation GO:0030316 62 0.522
Mouse
cell migration involved in heart development GO:0060973 8 0.521
regulation of cell projection organization GO:0031344 206 0.520
Zebrafish Mouse Worm
skeletal system development GO:0001501 356 0.516
Mouse
ovulation cycle GO:0042698 59 0.514
Human
ameboidal type cell migration GO:0001667 128 0.506
Fly
glial cell migration GO:0008347 7 0.505
Fly
exocrine system development GO:0035272 45 0.503
Fly
negative regulation of mammary gland epithelial cell proliferation GO:0033600 3 0.496
cell migration involved in gastrulation GO:0042074 13 0.495
Fly
cytokine mediated signaling pathway GO:0019221 115 0.494
Human
axonogenesis GO:0007409 274 0.493
endothelial cell migration GO:0043542 44 0.491
actin filament polymerization GO:0030041 44 0.489
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.488
Human Worm
forebrain cell migration GO:0021885 58 0.481
Mouse
motor neuron axon guidance GO:0008045 26 0.476
positive regulation of cell adhesion GO:0045785 80 0.473
Fly
cell migration involved in sprouting angiogenesis GO:0002042 9 0.472
regionalization GO:0003002 337 0.471
Fly
morphogenesis of a branching structure GO:0001763 203 0.469
regulation of extent of cell growth GO:0061387 52 0.460
Zebrafish Mouse Worm
regulation of myeloid leukocyte differentiation GO:0002761 58 0.459
Mouse
regulation of neuron differentiation GO:0045664 281 0.459
Zebrafish Mouse Worm
cerebral cortex cell migration GO:0021795 44 0.457
rhythmic process GO:0048511 174 0.450
Human
sprouting angiogenesis GO:0002040 26 0.450
smooth muscle cell migration GO:0014909 10 0.444
gastrulation GO:0007369 116 0.437
Fly
small gtpase mediated signal transduction GO:0007264 97 0.433
leukocyte chemotaxis GO:0030595 69 0.432
negative regulation of neuron projection development GO:0010977 50 0.428
Zebrafish Mouse Worm
spinal cord development GO:0021510 81 0.426
Rat
mononuclear cell migration GO:0071674 8 0.420
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.413
Zebrafish Mouse Worm
telencephalon cell migration GO:0022029 55 0.413
Mouse
mesoderm development GO:0007498 100 0.409
Fly
negative regulation of neuron differentiation GO:0045665 101 0.406
Zebrafish Mouse Worm
developmental cell growth GO:0048588 84 0.404
Human Zebrafish Mouse Worm
outflow tract morphogenesis GO:0003151 53 0.401
Fly
neuron recognition GO:0008038 25 0.398
Fly
regulation of cell motility GO:2000145 236 0.388
Fly
cerebral cortex development GO:0021987 86 0.387
heart formation GO:0060914 16 0.384
stem cell differentiation GO:0048863 268 0.383
salivary gland development GO:0007431 37 0.378
Fly
gland development GO:0048732 330 0.377
Mouse Fly
positive regulation of cell projection organization GO:0031346 95 0.373
neuron migration GO:0001764 122 0.369
Worm Fly
mesonephric epithelium development GO:0072163 94 0.366
cell chemotaxis GO:0060326 81 0.366
regulation of anatomical structure size GO:0090066 178 0.366
Zebrafish Mouse Worm
convergent extension GO:0060026 14 0.366
ureteric bud development GO:0001657 94 0.365
regulation of actin filament length GO:0030832 45 0.360
cellular response to hormone stimulus GO:0032870 150 0.355
Human
lateral inhibition GO:0046331 1 0.355
Fly
regulation of circadian rhythm GO:0042752 58 0.343
apoptotic process involved in development GO:1902742 28 0.341
Human
telencephalon development GO:0021537 186 0.340
Mouse
digestive tract development GO:0048565 190 0.340
Fly
positive regulation of peptidase activity GO:0010952 49 0.338
metanephros development GO:0001656 79 0.336
Mouse
blood vessel morphogenesis GO:0048514 285 0.335
positive regulation of neuron differentiation GO:0045666 141 0.330
chemotaxis GO:0006935 247 0.327
mesoderm morphogenesis GO:0048332 64 0.325
Fly
vascular process in circulatory system GO:0003018 62 0.323
positive regulation of behavior GO:0048520 40 0.321
Fly
renal system development GO:0072001 225 0.320
Mouse
neuromuscular process GO:0050905 99 0.310
regulation of actin filament polymerization GO:0030833 38 0.308
axon extension involved in axon guidance GO:0048846 14 0.307
Human Worm
cardioblast differentiation GO:0010002 13 0.299
regulation of mononuclear cell migration GO:0071675 6 0.297
kidney epithelium development GO:0072073 121 0.296
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.296
cardiac cell fate specification GO:0060912 2 0.295
negative regulation of response to cytokine stimulus GO:0060761 9 0.295
Human
negative regulation of cell motility GO:2000146 61 0.292
gonad development GO:0008406 141 0.287
Human Fly
forebrain generation of neurons GO:0021872 63 0.284
central nervous system neuron axonogenesis GO:0021955 28 0.284
Zebrafish
cellular response to growth factor stimulus GO:0071363 197 0.283
blood vessel endothelial cell migration GO:0043534 23 0.283
positive regulation of neuron projection development GO:0010976 79 0.275
central nervous system neuron development GO:0021954 67 0.271
Zebrafish
forebrain neuron differentiation GO:0021879 52 0.267
mammary gland epithelium development GO:0061180 65 0.265
Mouse
regulation of peptidase activity GO:0052547 96 0.264
branching morphogenesis of an epithelial tube GO:0048754 159 0.253
regulation of cell growth GO:0001558 91 0.250
Human Zebrafish Mouse Worm
forebrain neuron development GO:0021884 30 0.247
regulation of lamellipodium assembly GO:0010591 3 0.244
positive regulation of apoptotic process GO:0043065 217 0.243
positive regulation of programmed cell death GO:0043068 218 0.234
regulation of cellular component size GO:0032535 121 0.234
Zebrafish Mouse Worm
digestive system development GO:0055123 200 0.230
Fly
regulation of actin polymerization or depolymerization GO:0008064 45 0.223
negative regulation of smooth muscle cell migration GO:0014912 2 0.221
myeloid leukocyte differentiation GO:0002573 119 0.216
Mouse
epithelium migration GO:0090132 63 0.212
Fly
lamellipodium organization GO:0097581 29 0.212
pallium development GO:0021543 120 0.211
circadian rhythm GO:0007623 114 0.210
regulation of osteoclast differentiation GO:0045670 36 0.210
Mouse
cell substrate adhesion GO:0031589 130 0.202
convergent extension involved in organogenesis GO:0060029 7 0.200
epithelial cell migration GO:0010631 63 0.200
Fly
negative regulation of cell proliferation GO:0008285 296 0.198
positive regulation of axon extension GO:0045773 20 0.191
positive regulation of cell development GO:0010720 237 0.189
protein processing GO:0016485 163 0.189
negative regulation of epithelial cell proliferation GO:0050680 64 0.188
locomotion involved in locomotory behavior GO:0031987 8 0.183
single organismal cell cell adhesion GO:0016337 131 0.182
Mouse Fly
angiogenesis GO:0001525 201 0.179
development of primary sexual characteristics GO:0045137 143 0.177
Human Fly
regulation of axon guidance GO:1902667 13 0.172
Worm
gliogenesis GO:0042063 141 0.170
Fly
morphogenesis of a branching epithelium GO:0061138 193 0.170
anatomical structure homeostasis GO:0060249 145 0.164
actin polymerization or depolymerization GO:0008154 54 0.164
negative regulation of immune system process GO:0002683 209 0.157
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.157
cellular homeostasis GO:0019725 240 0.156
regulation of cellular component biogenesis GO:0044087 181 0.155
cell fate specification GO:0001708 72 0.147
cellular response to heparin GO:0071504 1 0.144
central nervous system neuron differentiation GO:0021953 162 0.140
Zebrafish
negative regulation of molecular function GO:0044092 258 0.139
zymogen activation GO:0031638 41 0.138
positive regulation of nervous system development GO:0051962 221 0.137
cardiocyte differentiation GO:0035051 87 0.137
muscle cell cellular homeostasis GO:0046716 12 0.133
synapse assembly GO:0007416 56 0.131
myeloid leukocyte migration GO:0097529 57 0.131
axonal fasciculation GO:0007413 15 0.129
negative regulation of phosphorylation GO:0042326 166 0.127
regulation of smooth muscle cell migration GO:0014910 6 0.124
regulation of epithelial cell proliferation GO:0050678 141 0.124
granulocyte chemotaxis GO:0071621 39 0.121
granulocyte migration GO:0097530 43 0.118
regulation of response to wounding GO:1903034 189 0.116
regulation of proteolysis GO:0030162 164 0.116
regulation of protein complex assembly GO:0043254 83 0.115
monocyte chemotaxis GO:0002548 5 0.106
protein maturation GO:0051604 176 0.105
response to alcohol GO:0097305 48 0.103
Human
regulation of retinal ganglion cell axon guidance GO:0090259 2 0.102
regulation of hydrolase activity GO:0051336 246 0.100
positive regulation of cellular amine metabolic process GO:0033240 5 0.100
response to nutrient levels GO:0031667 109 0.098
dendrite development GO:0016358 115 0.097
Fly
brain morphogenesis GO:0048854 32 0.096
regulation of leukocyte differentiation GO:1902105 159 0.092
Mouse
formation of primary germ layer GO:0001704 77 0.090
Fly
regulation of neutrophil chemotaxis GO:0090022 14 0.090
positive regulation of proteolysis GO:0045862 85 0.090
extracellular structure organization GO:0043062 148 0.085
negative regulation of epithelial cell migration GO:0010633 9 0.085
amine metabolic process GO:0009308 45 0.085
neutrophil chemotaxis GO:0030593 36 0.081
cellular amino acid metabolic process GO:0006520 103 0.080
regulation of neutrophil migration GO:1902622 14 0.080
negative regulation of response to wounding GO:1903035 77 0.080
negative regulation of cytoskeleton organization GO:0051494 36 0.079
establishment of organelle localization GO:0051656 122 0.079
Mouse
actin filament organization GO:0007015 113 0.078
locomotory behavior GO:0007626 195 0.078
bmp signaling pathway GO:0030509 93 0.076
leukocyte migration GO:0050900 124 0.076
regulation of granulocyte chemotaxis GO:0071622 17 0.074
regulation of hormone levels GO:0010817 211 0.073
regulation of cysteine type endopeptidase activity GO:2000116 65 0.073
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.073
ossification GO:0001503 216 0.072
regulation of response to cytokine stimulus GO:0060759 23 0.070
Human
positive regulation of endopeptidase activity GO:0010950 43 0.070
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.069
regulation of endothelial cell migration GO:0010594 22 0.068
elastic fiber assembly GO:0048251 4 0.068
female sex differentiation GO:0046660 84 0.066
Human
regulation of cellular amine metabolic process GO:0033238 20 0.065
bone marrow development GO:0048539 3 0.064
Mouse
activation of cysteine type endopeptidase activity GO:0097202 27 0.064
negative regulation of cellular component organization GO:0051129 194 0.064
Zebrafish Mouse Worm
appendage development GO:0048736 166 0.064
cellular response to lipid GO:0071396 145 0.061
response to steroid hormone GO:0048545 56 0.059
Human
response to organonitrogen compound GO:0010243 246 0.058
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.056
neutrophil migration GO:1990266 37 0.056
negative regulation of phosphorus metabolic process GO:0010563 184 0.055
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.053
negative regulation of organelle organization GO:0010639 90 0.052
regulation of cellular response to growth factor stimulus GO:0090287 82 0.052
cell matrix adhesion GO:0007160 68 0.052
compound eye development GO:0048749 1 0.051
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.050
regulation of cytoskeleton organization GO:0051493 122 0.050
carbohydrate metabolic process GO:0005975 230 0.050
nitrogen compound transport GO:0071705 271 0.050
regulation of epithelial cell migration GO:0010632 35 0.049
Fly
regulation of system process GO:0044057 200 0.049
cellular response to organonitrogen compound GO:0071417 145 0.049
extracellular matrix organization GO:0030198 147 0.048
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.047
regulation of endopeptidase activity GO:0052548 89 0.047
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.045
Mouse
palate development GO:0060021 76 0.045
regulation of wnt signaling pathway GO:0030111 123 0.045
respiratory tube development GO:0030323 167 0.043
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.043
epithelial cell proliferation GO:0050673 174 0.042
limb development GO:0060173 166 0.041
regulation of mapk cascade GO:0043408 248 0.041
canonical wnt signaling pathway GO:0060070 130 0.040
organonitrogen compound catabolic process GO:1901565 264 0.039
positive regulation of cell death GO:0010942 224 0.039
kidney morphogenesis GO:0060993 83 0.039
respiratory system development GO:0060541 190 0.039
Fly
negative regulation of actin filament polymerization GO:0030837 11 0.038
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.038
insulin processing GO:0030070 2 0.037
sulfur compound metabolic process GO:0006790 100 0.037
peptide hormone secretion GO:0030072 109 0.037
positive regulation of smooth muscle cell migration GO:0014911 4 0.036
skeletal muscle organ development GO:0060538 163 0.035
transmission of nerve impulse GO:0019226 76 0.034
response to heparin GO:0071503 1 0.034
cellular carbohydrate metabolic process GO:0044262 119 0.033
negative regulation of cell projection organization GO:0031345 56 0.033
Zebrafish Mouse Worm
regulation of cell substrate adhesion GO:0010810 73 0.033
positive regulation of apoptotic signaling pathway GO:2001235 95 0.032
regulation of actin filament based process GO:0032970 99 0.032
purine nucleoside catabolic process GO:0006152 205 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
cardiac cell fate commitment GO:0060911 10 0.031
myeloid cell differentiation GO:0030099 233 0.031
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.031
hormone secretion GO:0046879 128 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
regulation of apoptotic signaling pathway GO:2001233 197 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
bone development GO:0060348 120 0.031
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.031
organic hydroxy compound metabolic process GO:1901615 203 0.030
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.030
regulation of removal of superoxide radicals GO:2000121 4 0.030
negative regulation of protein complex assembly GO:0031333 25 0.030
cellular lipid metabolic process GO:0044255 323 0.030
nucleotide metabolic process GO:0009117 332 0.029
regulation of blood pressure GO:0008217 93 0.029
response to organic cyclic compound GO:0014070 198 0.029
Human
aromatic compound catabolic process GO:0019439 286 0.029
ras protein signal transduction GO:0007265 77 0.028
positive regulation of growth GO:0045927 104 0.028
cell growth GO:0016049 130 0.028
Human Zebrafish Mouse Worm
negative regulation of bmp signaling pathway GO:0030514 35 0.028
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.027
Mouse
protein polymerization GO:0051258 57 0.027
inositol phosphate mediated signaling GO:0048016 13 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
carbohydrate biosynthetic process GO:0016051 74 0.027
regulation of actin cytoskeleton organization GO:0032956 84 0.026
regulation of organelle organization GO:0033043 289 0.026
negative regulation of growth GO:0045926 99 0.026
Human Zebrafish Mouse Worm
cellular protein complex assembly GO:0043623 116 0.026
striated muscle tissue development GO:0014706 293 0.026
transmembrane transport GO:0055085 412 0.026
amide transport GO:0042886 138 0.025
corticospinal tract morphogenesis GO:0021957 6 0.025
skeletal system morphogenesis GO:0048705 203 0.024
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.024
cellular polysaccharide metabolic process GO:0044264 38 0.024
regulation of organ morphogenesis GO:2000027 144 0.024
embryonic organ morphogenesis GO:0048562 276 0.024
regulation of inflammatory response GO:0050727 147 0.023
negative regulation of osteoclast differentiation GO:0045671 12 0.023
Mouse
sensory organ morphogenesis GO:0090596 242 0.023
muscle system process GO:0003012 141 0.023
peptide transport GO:0015833 133 0.023
regulation of reactive oxygen species metabolic process GO:2000377 40 0.023
oxidation reduction process GO:0055114 342 0.023
heart trabecula morphogenesis GO:0061384 26 0.022
peptide secretion GO:0002790 114 0.022
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.022
protein catabolic process GO:0030163 221 0.022
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.022
mesoderm formation GO:0001707 62 0.022
Fly
purine ribonucleoside metabolic process GO:0046128 241 0.022
purine containing compound metabolic process GO:0072521 311 0.022
regulation of fat cell differentiation GO:0045598 81 0.022
mesonephric tubule morphogenesis GO:0072171 63 0.022
response to peptide hormone GO:0043434 127 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
response to oxidative stress GO:0006979 123 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
endochondral bone morphogenesis GO:0060350 50 0.020
regulation of homeostatic process GO:0032844 182 0.020
regulation of osteoblast differentiation GO:0045667 67 0.020
wnt signaling pathway GO:0016055 188 0.020
cellular ketone metabolic process GO:0042180 84 0.020
embryonic placenta development GO:0001892 98 0.020
reactive oxygen species metabolic process GO:0072593 84 0.019
neuron apoptotic process GO:0051402 142 0.019
negative regulation of ossification GO:0030279 49 0.019
lung development GO:0030324 164 0.019
cellular amine metabolic process GO:0044106 44 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
mammary gland epithelial cell proliferation GO:0033598 24 0.019
fat cell differentiation GO:0045444 160 0.019
regulation of bmp signaling pathway GO:0030510 60 0.018
cellular response to acid chemical GO:0071229 68 0.018
protein oligomerization GO:0051259 67 0.018
retinal blood vessel morphogenesis GO:0061304 3 0.018
removal of superoxide radicals GO:0019430 12 0.018
regulation of lamellipodium organization GO:1902743 5 0.018
regulation of striated muscle cell differentiation GO:0051153 81 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
developmental maturation GO:0021700 193 0.018
muscle hypertrophy GO:0014896 24 0.018
response to amino acid GO:0043200 37 0.018
cellular response to extracellular stimulus GO:0031668 81 0.017
protein targeting GO:0006605 143 0.017
regulation of cell shape GO:0008360 39 0.017
purine containing compound catabolic process GO:0072523 213 0.017
negative regulation of cell development GO:0010721 169 0.017
Zebrafish Mouse Worm
regulation of angiotensin metabolic process GO:0060177 4 0.017
mesenchyme development GO:0060485 152 0.017
intracellular protein transport GO:0006886 204 0.017
regulation of angiogenesis GO:0045765 81 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
regulation of blood vessel remodeling GO:0060312 3 0.017
organelle localization GO:0051640 179 0.017
Mouse
embryonic limb morphogenesis GO:0030326 126 0.017
peptidyl tyrosine phosphorylation GO:0018108 143 0.017
cellular response to amino acid stimulus GO:0071230 29 0.017
glycoprotein metabolic process GO:0009100 116 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
innate immune response GO:0045087 157 0.017
response to oxygen levels GO:0070482 62 0.017
embryonic appendage morphogenesis GO:0035113 126 0.017
epithelial tube formation GO:0072175 130 0.017
trabecula morphogenesis GO:0061383 40 0.017
erythrocyte differentiation GO:0030218 88 0.017
cardiac muscle tissue development GO:0048738 130 0.016
regulation of morphogenesis of a branching structure GO:0060688 53 0.016
negative regulation of nervous system development GO:0051961 156 0.016
Zebrafish Mouse Worm
circulatory system process GO:0003013 197 0.016
response to radiation GO:0009314 165 0.016
endochondral bone growth GO:0003416 19 0.016
neuron death GO:0070997 154 0.016
rac protein signal transduction GO:0016601 13 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
muscle tissue development GO:0060537 308 0.016
cell cell signaling involved in cell fate commitment GO:0045168 35 0.016
Fly
nucleoside catabolic process GO:0009164 206 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
peptidyl tyrosine modification GO:0018212 145 0.015
cellular response to oxygen radical GO:0071450 14 0.015
lipid biosynthetic process GO:0008610 179 0.015
negative regulation of cell adhesion GO:0007162 45 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
establishment of vesicle localization GO:0051650 81 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
apoptotic signaling pathway GO:0097190 306 0.015
multicellular organismal signaling GO:0035637 91 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
heterocycle catabolic process GO:0046700 280 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
placenta development GO:0001890 140 0.015
actin cytoskeleton organization GO:0030036 220 0.015
labyrinthine layer development GO:0060711 49 0.015
inflammatory response GO:0006954 244 0.015
response to extracellular stimulus GO:0009991 127 0.015
leukocyte differentiation GO:0002521 342 0.014
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.014
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
cardiac septum development GO:0003279 59 0.014
regulation of ketone biosynthetic process GO:0010566 2 0.014
regulation of defense response GO:0031347 233 0.014
regulation of protein kinase b signaling GO:0051896 56 0.014
tissue remodeling GO:0048771 102 0.014
sulfur compound biosynthetic process GO:0044272 37 0.014
notch signaling pathway GO:0007219 71 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
Human
regulation of peptide secretion GO:0002791 77 0.014
heart trabecula formation GO:0060347 14 0.014
response to vitamin d GO:0033280 3 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
antibacterial peptide production GO:0002778 2 0.014
sensory perception of mechanical stimulus GO:0050954 107 0.014
mitotic cell cycle process GO:1903047 159 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
cytoplasmic transport GO:0016482 234 0.013
trabecula formation GO:0060343 24 0.013
muscle cell development GO:0055001 133 0.013
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.013
odontogenesis GO:0042476 78 0.013
embryonic skeletal system morphogenesis GO:0048704 91 0.013
response to inorganic substance GO:0010035 96 0.013
gtp metabolic process GO:0046039 144 0.013
cytokine production GO:0001816 319 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
mesendoderm development GO:0048382 3 0.013
cation transport GO:0006812 399 0.013
cell cell junction organization GO:0045216 72 0.013
mapk cascade GO:0000165 281 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
positive regulation of cell substrate adhesion GO:0010811 47 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
cation transmembrane transport GO:0098655 266 0.013
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.013

Slit3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
urinary system disease DOID:18 0 0.050
nervous system disease DOID:863 0 0.031
muscular disease DOID:0080000 0 0.013
musculoskeletal system disease DOID:17 0 0.013
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013