|
|
positive regulation of cell proliferation involved in heart valve morphogenesis
|
GO:0003251 |
1 |
1.000
|
Mouse |
|
|
cell proliferation involved in heart valve morphogenesis
|
GO:0003249 |
1 |
0.999
|
Mouse |
|
|
kidney mesenchyme morphogenesis
|
GO:0072131 |
4 |
0.998
|
Mouse |
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
7 |
0.997
|
|
|
|
metanephric mesenchyme morphogenesis
|
GO:0072133 |
4 |
0.997
|
Mouse |
|
|
brainstem development
|
GO:0003360 |
3 |
0.990
|
Mouse |
|
|
endothelial cell activation
|
GO:0042118 |
1 |
0.989
|
Mouse |
|
|
nephrogenic mesenchyme development
|
GO:0072076 |
3 |
0.989
|
Mouse |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.984
|
Mouse |
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
2 |
0.979
|
Mouse |
|
|
negative regulation of osteoblast proliferation
|
GO:0033689 |
4 |
0.972
|
Mouse |
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.970
|
Fly |
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.966
|
Mouse |
|
|
negative regulation of peptidyl threonine phosphorylation
|
GO:0010801 |
6 |
0.965
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.958
|
Mouse |
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.956
|
Mouse |
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
2 |
0.948
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.940
|
Zebrafish Mouse |
|
|
digestive tract development
|
GO:0048565 |
190 |
0.938
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.936
|
Mouse |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.935
|
Mouse |
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.934
|
Mouse |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.931
|
|
|
|
germline cell cycle switching mitotic to meiotic cell cycle
|
GO:0051729 |
1 |
0.928
|
Worm |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.928
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.927
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.926
|
Mouse |
|
|
nephrogenic mesenchyme morphogenesis
|
GO:0072134 |
2 |
0.922
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.921
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.916
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.899
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.898
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
68 |
0.898
|
Mouse |
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
23 |
0.898
|
Mouse |
|
|
digestive system development
|
GO:0055123 |
200 |
0.867
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.864
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.863
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.855
|
|
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
4 |
0.851
|
Mouse |
|
|
negative regulation of peptidyl serine phosphorylation
|
GO:0033137 |
10 |
0.850
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.846
|
Mouse |
|
|
wound healing
|
GO:0042060 |
157 |
0.844
|
Mouse |
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.842
|
Mouse |
|
|
smad protein signal transduction
|
GO:0060395 |
21 |
0.833
|
Mouse |
|
|
regulation of cell proliferation involved in heart valve morphogenesis
|
GO:0003250 |
1 |
0.831
|
Mouse |
|
|
neural tube development
|
GO:0021915 |
160 |
0.828
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
12 |
0.823
|
Fly |
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.820
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.809
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.809
|
Mouse |
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.803
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.801
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.796
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.794
|
Mouse |
|
|
segmentation
|
GO:0035282 |
93 |
0.793
|
Mouse Fly |
|
|
epithelial to mesenchymal transition involved in endocardial cushion formation
|
GO:0003198 |
10 |
0.791
|
Mouse |
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.789
|
Mouse |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.787
|
Mouse Fly |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.783
|
Mouse Fly |
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.783
|
Mouse |
|
|
regulation of osteoblast proliferation
|
GO:0033688 |
15 |
0.782
|
Mouse |
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.780
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.777
|
Mouse |
|
|
cell cycle switching mitotic to meiotic cell cycle
|
GO:0051728 |
1 |
0.766
|
Worm |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.758
|
Mouse |
|
|
regulation of peptidyl threonine phosphorylation
|
GO:0010799 |
12 |
0.758
|
Mouse |
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.752
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.751
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.749
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.748
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.745
|
Mouse |
|
|
neural tube closure
|
GO:0001843 |
90 |
0.738
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.734
|
Mouse Fly |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.734
|
Mouse Fly |
|
|
neural tube formation
|
GO:0001841 |
108 |
0.729
|
|
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
2 |
0.723
|
|
|
|
osteoblast fate commitment
|
GO:0002051 |
4 |
0.718
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.716
|
Mouse |
|
|
somite rostral caudal axis specification
|
GO:0032525 |
13 |
0.714
|
Mouse |
|
|
paraxial mesoderm morphogenesis
|
GO:0048340 |
10 |
0.713
|
Mouse |
|
|
gastrulation
|
GO:0007369 |
116 |
0.710
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.710
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
50 |
0.709
|
Mouse |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.708
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.707
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
93 |
0.705
|
Mouse |
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.704
|
Mouse |
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.702
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.700
|
Mouse |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.697
|
|
|
|
negative regulation of osteoblast differentiation
|
GO:0045668 |
30 |
0.696
|
Mouse |
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.691
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.683
|
Mouse |
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.679
|
Mouse |
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.676
|
Mouse |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.673
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.670
|
Mouse |
|
|
heart valve development
|
GO:0003170 |
23 |
0.668
|
Mouse |
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.667
|
|
|
|
osteoblast development
|
GO:0002076 |
17 |
0.666
|
Mouse |
|
|
endoderm formation
|
GO:0001706 |
20 |
0.665
|
Mouse Fly |
|
|
rhythmic process
|
GO:0048511 |
174 |
0.663
|
|
|
|
embryonic axis specification
|
GO:0000578 |
30 |
0.660
|
Mouse |
|
|
synapse organization
|
GO:0050808 |
125 |
0.655
|
Fly |
|
|
ossification
|
GO:0001503 |
216 |
0.654
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.652
|
Mouse |
|
|
nephron tubule morphogenesis
|
GO:0072078 |
68 |
0.652
|
Mouse |
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
26 |
0.648
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.644
|
Fly |
|
|
negative regulation of wound healing
|
GO:0061045 |
14 |
0.641
|
Mouse |
|
|
skin development
|
GO:0043588 |
220 |
0.634
|
Mouse |
|
|
respiratory system development
|
GO:0060541 |
190 |
0.634
|
Mouse |
|
|
epidermis development
|
GO:0008544 |
187 |
0.630
|
Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.630
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.627
|
Mouse |
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
18 |
0.621
|
Mouse |
|
|
dendrite development
|
GO:0016358 |
115 |
0.621
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.617
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.616
|
|
|
|
sebaceous gland development
|
GO:0048733 |
7 |
0.614
|
Mouse |
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
13 |
0.608
|
Mouse |
|
|
oocyte construction
|
GO:0007308 |
2 |
0.605
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
35 |
0.605
|
Mouse |
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
21 |
0.602
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.601
|
|
|
|
somite development
|
GO:0061053 |
81 |
0.593
|
Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.585
|
Mouse |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.580
|
Fly |
|
|
endocardial cushion morphogenesis
|
GO:0003203 |
18 |
0.571
|
Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.569
|
Mouse |
|
|
endocardial cushion formation
|
GO:0003272 |
13 |
0.568
|
Mouse |
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.567
|
Fly |
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.565
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.562
|
Mouse |
|
|
oogenesis
|
GO:0048477 |
56 |
0.557
|
Fly |
|
|
kidney development
|
GO:0001822 |
213 |
0.555
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.553
|
Mouse |
|
|
germ line stem cell division
|
GO:0042078 |
2 |
0.538
|
Fly |
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
10 |
0.538
|
Mouse |
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.525
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.521
|
Mouse |
|
|
smad protein complex assembly
|
GO:0007183 |
1 |
0.520
|
Human |
|
|
renal system development
|
GO:0072001 |
225 |
0.520
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.518
|
Mouse |
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.516
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.514
|
|
|
|
regulation of hair cycle
|
GO:0042634 |
11 |
0.514
|
Mouse |
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.512
|
Worm Fly |
|
|
mesonephros development
|
GO:0001823 |
97 |
0.511
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.508
|
Mouse |
|
|
tube formation
|
GO:0035148 |
140 |
0.508
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.507
|
|
|
|
atrioventricular canal development
|
GO:0036302 |
5 |
0.502
|
Mouse |
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.496
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.493
|
Zebrafish Mouse Fly |
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.493
|
Mouse |
|
|
palate development
|
GO:0060021 |
76 |
0.493
|
Mouse |
|
|
tube closure
|
GO:0060606 |
91 |
0.479
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.478
|
Mouse |
|
|
kidney morphogenesis
|
GO:0060993 |
83 |
0.475
|
Mouse |
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.473
|
Mouse |
|
|
blood coagulation
|
GO:0007596 |
76 |
0.472
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
22 |
0.461
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.450
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
22 |
0.450
|
Mouse |
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.447
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.443
|
Mouse |
|
|
blastoderm segmentation
|
GO:0007350 |
13 |
0.441
|
Fly |
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.440
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.439
|
Mouse Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.433
|
|
|
|
endocardial cushion development
|
GO:0003197 |
26 |
0.431
|
Mouse |
|
|
cell migration involved in gastrulation
|
GO:0042074 |
13 |
0.430
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.426
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.424
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.423
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.421
|
Mouse |
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.419
|
Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.415
|
Mouse |
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.413
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.412
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.409
|
Mouse |
|
|
learning
|
GO:0007612 |
98 |
0.408
|
|
|
|
cardiac muscle cell proliferation
|
GO:0060038 |
31 |
0.406
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.403
|
Worm Fly |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.401
|
|
|
|
stem cell division
|
GO:0017145 |
30 |
0.400
|
Fly |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.399
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
44 |
0.399
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.399
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
62 |
0.398
|
Mouse |
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.395
|
Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.394
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.391
|
Mouse |
|
|
positive regulation of chondrocyte differentiation
|
GO:0032332 |
13 |
0.386
|
Mouse |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.381
|
Mouse Fly |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.381
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.379
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
34 |
0.379
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.378
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.375
|
Fly |
|
|
urogenital system development
|
GO:0001655 |
261 |
0.374
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.373
|
Mouse |
|
|
cartilage development
|
GO:0051216 |
140 |
0.373
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.370
|
Mouse |
|
|
ventricular septum development
|
GO:0003281 |
42 |
0.370
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.368
|
Mouse |
|
|
mesenchyme morphogenesis
|
GO:0072132 |
32 |
0.366
|
Mouse |
|
|
transforming growth factor beta2 production
|
GO:0032906 |
2 |
0.366
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.366
|
Mouse |
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.365
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.362
|
Mouse |
|
|
response to bmp
|
GO:0071772 |
14 |
0.360
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.360
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.358
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.358
|
Mouse |
|
|
stem cell development
|
GO:0048864 |
219 |
0.358
|
Mouse Fly |
|
|
cellular response to bmp stimulus
|
GO:0071773 |
14 |
0.357
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
28 |
0.357
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.355
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.352
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.351
|
Mouse |
|
|
cardiac septum morphogenesis
|
GO:0060411 |
46 |
0.347
|
Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.345
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
47 |
0.344
|
Fly |
|
|
organ growth
|
GO:0035265 |
117 |
0.344
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.343
|
|
|
|
habituation
|
GO:0046959 |
3 |
0.343
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.343
|
Fly |
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.342
|
Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.340
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.338
|
Mouse |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.336
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.336
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.335
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.334
|
Mouse |
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.332
|
Mouse |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.328
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.327
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
6 |
0.327
|
Mouse |
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.324
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.324
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.324
|
|
|
|
metanephric mesenchyme development
|
GO:0072075 |
10 |
0.321
|
Mouse |
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.320
|
Mouse |
|
|
endocrine system development
|
GO:0035270 |
98 |
0.317
|
Mouse |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.316
|
Mouse |
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.312
|
Mouse |
|
|
molting cycle
|
GO:0042303 |
90 |
0.311
|
Mouse |
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.308
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.304
|
Mouse |
|
|
endocardial cell differentiation
|
GO:0060956 |
4 |
0.304
|
Mouse |
|
|
forebrain development
|
GO:0030900 |
302 |
0.303
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.301
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.296
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.294
|
|
|
|
endoderm development
|
GO:0007492 |
45 |
0.294
|
Mouse Fly |
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.292
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.291
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
22 |
0.290
|
Mouse |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
34 |
0.289
|
Worm |
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.289
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.288
|
Mouse |
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.287
|
Mouse |
|
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
4 |
0.286
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.286
|
Mouse |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.286
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.284
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.283
|
Mouse Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.282
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.277
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.277
|
|
|
|
mesoderm formation
|
GO:0001707 |
62 |
0.277
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.275
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.275
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.270
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
53 |
0.270
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.269
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.268
|
Mouse |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.268
|
Mouse |
|
|
embryonic heart tube development
|
GO:0035050 |
65 |
0.265
|
Mouse |
|
|
oocyte development
|
GO:0048599 |
33 |
0.262
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.261
|
Mouse |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.260
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
27 |
0.258
|
Mouse |
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.258
|
Mouse |
|
|
cell fate determination
|
GO:0001709 |
32 |
0.257
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
26 |
0.255
|
Mouse |
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.252
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.252
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.246
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.246
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.246
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.245
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.244
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.241
|
Mouse |
|
|
cell division
|
GO:0051301 |
120 |
0.241
|
Fly |
|
|
protein acylation
|
GO:0043543 |
64 |
0.239
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.236
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.235
|
Mouse |
|
|
cell growth
|
GO:0016049 |
130 |
0.234
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.232
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.231
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.230
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.230
|
Mouse |
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.230
|
Mouse |
|
|
regulation of hair follicle development
|
GO:0051797 |
9 |
0.230
|
Mouse |
|
|
hormone secretion
|
GO:0046879 |
128 |
0.228
|
Mouse |
|
|
heart valve morphogenesis
|
GO:0003179 |
21 |
0.224
|
Mouse |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.223
|
Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.222
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.222
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.221
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.220
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.220
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.220
|
Mouse |
|
|
endodermal cell differentiation
|
GO:0035987 |
14 |
0.218
|
Fly |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.216
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.215
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.213
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.212
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.212
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.212
|
Mouse |
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.209
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.209
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.208
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
29 |
0.207
|
Mouse |
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.207
|
Worm Fly |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.206
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
51 |
0.206
|
Mouse |
|
|
positive regulation of cartilage development
|
GO:0061036 |
18 |
0.206
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
83 |
0.205
|
Mouse |
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
6 |
0.204
|
Fly |
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.204
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.202
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.202
|
Mouse |
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
61 |
0.202
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.202
|
Mouse |
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.202
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.201
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.200
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.199
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.199
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.199
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.198
|
Mouse |
|
|
hemostasis
|
GO:0007599 |
78 |
0.197
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.196
|
Mouse |
|
|
cell cycle switching
|
GO:0060184 |
1 |
0.196
|
Worm |
|
|
bone development
|
GO:0060348 |
120 |
0.195
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.194
|
Mouse |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.193
|
|
|
|
negative regulation of ripoptosome assembly involved in necroptotic process
|
GO:1902443 |
3 |
0.191
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.191
|
|
|
|
convergent extension
|
GO:0060026 |
14 |
0.190
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.190
|
Mouse |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.188
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.187
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.187
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.187
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.186
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.185
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.185
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.185
|
Fly |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.184
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.184
|
|
|
|
mechanoreceptor differentiation
|
GO:0042490 |
67 |
0.182
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.182
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.181
|
Fly |
|
|
muscle cell development
|
GO:0055001 |
133 |
0.180
|
|
|
|
ventricular cardiac muscle tissue development
|
GO:0003229 |
38 |
0.177
|
Mouse |
|
|
axon target recognition
|
GO:0007412 |
4 |
0.175
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.174
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.174
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.174
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.171
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.171
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.170
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.170
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
33 |
0.169
|
Mouse |
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
13 |
0.169
|
Mouse |
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
63 |
0.169
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.169
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.168
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.167
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.167
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.164
|
Mouse |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.164
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
39 |
0.163
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
4 |
0.162
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.161
|
|
|
|
mesenchymal cell proliferation
|
GO:0010463 |
44 |
0.160
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.158
|
Mouse |
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.157
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.156
|
Mouse |
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
23 |
0.156
|
|
|
|
pericardium development
|
GO:0060039 |
16 |
0.156
|
Mouse |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.156
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.155
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.155
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.154
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.153
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.152
|
Mouse |
|
|
endothelium development
|
GO:0003158 |
45 |
0.152
|
Mouse |
|
|
cardiac septum development
|
GO:0003279 |
59 |
0.151
|
Mouse |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.150
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.148
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
50 |
0.147
|
Mouse |
|
|
regulation of cell proliferation involved in heart morphogenesis
|
GO:2000136 |
15 |
0.147
|
Mouse |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.147
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.146
|
|
|
|
cardiac muscle tissue growth
|
GO:0055017 |
37 |
0.145
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.144
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.143
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.143
|
|
|
|
smooth muscle tissue development
|
GO:0048745 |
22 |
0.143
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.142
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.142
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.142
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.141
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.140
|
Mouse |
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
8 |
0.140
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.140
|
|
|
|
osteoblast proliferation
|
GO:0033687 |
18 |
0.140
|
Mouse |
|
|
midbrain development
|
GO:0030901 |
35 |
0.139
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.137
|
|
|
|
maintenance of apical basal cell polarity
|
GO:0035090 |
3 |
0.137
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
29 |
0.134
|
Fly |
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.134
|
Mouse |
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.133
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.133
|
Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.133
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.132
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.132
|
Mouse |
|
|
determination of heart left right asymmetry
|
GO:0061371 |
48 |
0.131
|
Mouse |
|
|
peptide secretion
|
GO:0002790 |
114 |
0.131
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.130
|
Mouse |
|
|
insulin secretion
|
GO:0030073 |
89 |
0.130
|
Mouse |
|
|
heart valve formation
|
GO:0003188 |
10 |
0.130
|
Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.130
|
|
|
|
regulation of cardiac cell fate specification
|
GO:2000043 |
1 |
0.128
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.128
|
Mouse |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.127
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.127
|
Worm Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.125
|
|
|
|
positive regulation of synapse assembly
|
GO:0051965 |
18 |
0.125
|
Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.125
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.124
|
Mouse |
|
|
artery development
|
GO:0060840 |
53 |
0.124
|
Mouse |
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.123
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.123
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.122
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.122
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.121
|
|
|
|
response to cholesterol
|
GO:0070723 |
4 |
0.121
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.120
|
Mouse |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.119
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.118
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
15 |
0.117
|
Worm |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.117
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.115
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.115
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
45 |
0.114
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.114
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.114
|
Mouse |
|
|
neural crest cell differentiation
|
GO:0014033 |
54 |
0.114
|
Mouse |
|
|
appendage development
|
GO:0048736 |
166 |
0.113
|
Fly |
|
|
regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0000083 |
3 |
0.113
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.113
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.112
|
Fly |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.112
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.112
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.112
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.111
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.111
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.110
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.110
|
Mouse |
|
|
endocardium development
|
GO:0003157 |
10 |
0.110
|
Mouse |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.110
|
Mouse |
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.109
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.109
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.108
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.108
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.108
|
Mouse |
|
|
connective tissue development
|
GO:0061448 |
179 |
0.106
|
|
|
|
trunk segmentation
|
GO:0035290 |
4 |
0.106
|
Fly |
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.106
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.106
|
Fly |
|
|
inner ear receptor stereocilium organization
|
GO:0060122 |
23 |
0.105
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.103
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.103
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.102
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.102
|
Mouse |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.102
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.101
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.101
|
|
