Mus musculus

18 known processes

Smc1b

structural maintenance of chromosomes 1B

(Aliases: SMC1beta,Smc1l2,SMC-1B)

Smc1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synapsis GO:0007129 34 0.879
pirna metabolic process GO:0034587 12 0.820
male meiosis GO:0007140 37 0.578
meiosis i GO:0007127 60 0.549
meiotic cell cycle process GO:1903046 77 0.402
dna methylation involved in gamete generation GO:0043046 15 0.330
meiotic cell cycle GO:0051321 122 0.279
meiotic nuclear division GO:0007126 115 0.275
chromosome organization involved in meiosis GO:0070192 39 0.274
fertilization GO:0009566 127 0.264
dna recombination GO:0006310 92 0.238
organelle fission GO:0048285 170 0.173
male gamete generation GO:0048232 285 0.166
nuclear division GO:0000280 158 0.154
spermatogenesis GO:0007283 284 0.138
cellular response to dna damage stimulus GO:0006974 207 0.122
cellular lipid metabolic process GO:0044255 323 0.122
dna metabolic process GO:0006259 303 0.114
response to radiation GO:0009314 165 0.093
transmembrane transport GO:0055085 412 0.089
nitrogen compound transport GO:0071705 271 0.075
regulation of transferase activity GO:0051338 263 0.071
methylation GO:0032259 134 0.070
response to light stimulus GO:0009416 135 0.070
dna repair GO:0006281 107 0.067
regulation of cellular amine metabolic process GO:0033238 20 0.066
detection of abiotic stimulus GO:0009582 60 0.062
ion transmembrane transport GO:0034220 361 0.062
regulation of membrane potential GO:0042391 192 0.060
cell maturation GO:0048469 127 0.056
muscle contraction GO:0006936 101 0.056
double strand break repair GO:0006302 48 0.055
macromolecule methylation GO:0043414 120 0.055
amine metabolic process GO:0009308 45 0.054
placenta development GO:0001890 140 0.054
detection of external stimulus GO:0009581 61 0.053
cofactor transport GO:0051181 4 0.052
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
regulation of system process GO:0044057 200 0.050
cation transmembrane transport GO:0098655 266 0.050
cellular amino acid metabolic process GO:0006520 103 0.048
cellular amine metabolic process GO:0044106 44 0.046
inflammatory response GO:0006954 244 0.045
muscle system process GO:0003012 141 0.044
cellular ketone metabolic process GO:0042180 84 0.044
regionalization GO:0003002 337 0.042
multicellular organismal signaling GO:0035637 91 0.041
mapk cascade GO:0000165 281 0.040
sulfur compound metabolic process GO:0006790 100 0.040
germ cell development GO:0007281 185 0.039
dna modification GO:0006304 50 0.039
stem cell differentiation GO:0048863 268 0.039
Mouse
t cell activation GO:0042110 289 0.039
inorganic ion transmembrane transport GO:0098660 234 0.038
inorganic cation transmembrane transport GO:0098662 207 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
stem cell development GO:0048864 219 0.038
Mouse
dna alkylation GO:0006305 43 0.037
regulation of protein kinase activity GO:0045859 232 0.037
gonad development GO:0008406 141 0.037
oocyte maturation GO:0001556 18 0.036
vitamin a metabolic process GO:0006776 2 0.035
positive regulation of protein modification process GO:0031401 299 0.035
rhythmic process GO:0048511 174 0.035
dna methylation GO:0006306 43 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.035
peptidyl amino acid modification GO:0018193 336 0.034
sensory perception GO:0007600 245 0.034
exocytosis GO:0006887 121 0.034
skin development GO:0043588 220 0.033
developmental maturation GO:0021700 193 0.033
carbohydrate metabolic process GO:0005975 230 0.033
epidermis development GO:0008544 187 0.033
carbohydrate biosynthetic process GO:0016051 74 0.033
embryonic organ morphogenesis GO:0048562 276 0.033
diterpenoid metabolic process GO:0016101 24 0.032
recombinational repair GO:0000725 21 0.031
cellular chemical homeostasis GO:0055082 215 0.031
positive regulation of protein phosphorylation GO:0001934 242 0.030
regulation of ion transport GO:0043269 215 0.030
mitotic cell cycle process GO:1903047 159 0.030
cell type specific apoptotic process GO:0097285 268 0.030
regulation of kinase activity GO:0043549 249 0.029
regulation of defense response GO:0031347 233 0.028
synaptonemal complex organization GO:0070193 15 0.028
oogenesis GO:0048477 56 0.028
reciprocal dna recombination GO:0035825 16 0.028
negative regulation of molecular function GO:0044092 258 0.028
gene silencing by rna GO:0031047 19 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
regulation of interleukin 1 alpha production GO:0032650 4 0.027
blood circulation GO:0008015 195 0.027
protein maturation GO:0051604 176 0.027
reactive oxygen species metabolic process GO:0072593 84 0.027
nucleotide metabolic process GO:0009117 332 0.027
chromosome segregation GO:0007059 48 0.027
circulatory system process GO:0003013 197 0.026
maintenance of location GO:0051235 89 0.026
regulation of cell cycle GO:0051726 281 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
cation transport GO:0006812 399 0.025
cation homeostasis GO:0055080 212 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
organelle localization GO:0051640 179 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
response to lipopolysaccharide GO:0032496 128 0.025
regulation of ion transmembrane transport GO:0034765 119 0.025
striated muscle contraction GO:0006941 45 0.025
regulation of mapk cascade GO:0043408 248 0.025
chromatin modification GO:0016568 187 0.024
response to inorganic substance GO:0010035 96 0.024
oocyte differentiation GO:0009994 35 0.024
muscle cell differentiation GO:0042692 261 0.024
camera type eye development GO:0043010 266 0.024
regulation of mitotic cell cycle GO:0007346 126 0.023
sequestering of metal ion GO:0051238 19 0.023
female gamete generation GO:0007292 74 0.023
protein processing GO:0016485 163 0.023
blood vessel morphogenesis GO:0048514 285 0.023
regulation of cell projection organization GO:0031344 206 0.022
transmission of nerve impulse GO:0019226 76 0.022
neuronal action potential GO:0019228 54 0.022
action potential GO:0001508 78 0.022
sensory perception of mechanical stimulus GO:0050954 107 0.022
regulation of homeostatic process GO:0032844 182 0.022
male sex differentiation GO:0046661 109 0.022
dendrite development GO:0016358 115 0.022
cellularization GO:0007349 1 0.022
response to acid chemical GO:0001101 111 0.022
adult behavior GO:0030534 135 0.022
positive regulation of thymocyte migration GO:2000412 2 0.022
immune effector process GO:0002252 321 0.022
positive regulation of kinase activity GO:0033674 155 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
heterocycle catabolic process GO:0046700 280 0.021
regulation of cell cycle process GO:0010564 160 0.021
cell adhesion GO:0007155 329 0.021
intracellular protein transport GO:0006886 204 0.021
ribonucleoside metabolic process GO:0009119 245 0.020
mitotic nuclear division GO:0007067 48 0.020
stem cell maintenance GO:0019827 130 0.020
Mouse
multicellular organismal homeostasis GO:0048871 164 0.020
carboxylic acid transport GO:0046942 100 0.020
retinoid metabolic process GO:0001523 24 0.020
anion transport GO:0006820 177 0.020
reciprocal meiotic recombination GO:0007131 16 0.020
memory GO:0007613 58 0.020
chromatin organization GO:0006325 206 0.019
microtubule based process GO:0007017 236 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
glucose homeostasis GO:0042593 128 0.019
aromatic compound catabolic process GO:0019439 286 0.019
neuron death GO:0070997 154 0.019
apoptotic signaling pathway GO:0097190 306 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
macromolecule catabolic process GO:0009057 281 0.019
ribonucleoside monophosphate metabolic process GO:0009161 80 0.018
synaptonemal complex assembly GO:0007130 13 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
protein kinase b signaling GO:0043491 74 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
regulation of inflammatory response GO:0050727 147 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
sensory organ morphogenesis GO:0090596 242 0.018
regulation of response to wounding GO:1903034 189 0.018
positive regulation of cell development GO:0010720 237 0.018
mitochondrion organization GO:0007005 134 0.018
response to peptide GO:1901652 136 0.018
signal transduction by p53 class mediator GO:0072331 51 0.018
oxidation reduction process GO:0055114 342 0.018
organic acid transport GO:0015849 101 0.017
cognition GO:0050890 149 0.017
protein localization to organelle GO:0033365 185 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
regulation of muscle system process GO:0090257 80 0.017
nucleocytoplasmic transport GO:0006913 139 0.016
adult locomotory behavior GO:0008344 91 0.016
gland development GO:0048732 330 0.016
protein catabolic process GO:0030163 221 0.016
oocyte axis specification GO:0007309 2 0.016
development of primary sexual characteristics GO:0045137 143 0.016
positive regulation of transferase activity GO:0051347 167 0.016
regulation of cell migration GO:0030334 219 0.016
vascular process in circulatory system GO:0003018 62 0.016
divalent inorganic cation transport GO:0072511 178 0.016
organic anion transport GO:0015711 137 0.016
regulation of transmembrane transport GO:0034762 128 0.016
positive regulation of interleukin 1 alpha production GO:0032730 4 0.016
olfactory learning GO:0008355 2 0.016
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.016
negative regulation of cell cycle process GO:0010948 69 0.016
regulation of thymocyte migration GO:2000410 2 0.016
regulation of secretion by cell GO:1903530 249 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.015
locomotory behavior GO:0007626 195 0.015
purine containing compound catabolic process GO:0072523 213 0.015
activation of mapk activity involved in innate immune response GO:0035419 2 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
leukocyte apoptotic process GO:0071887 71 0.015
positive regulation of mapk cascade GO:0043410 170 0.015
amino acid transport GO:0006865 61 0.015
mitotic cell cycle GO:0000278 195 0.015
response to oxidative stress GO:0006979 123 0.015
positive regulation of glutamate secretion GO:0014049 2 0.015
organelle assembly GO:0070925 177 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.015
rna interference GO:0016246 2 0.015
negative regulation of transposition GO:0010529 2 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
divalent metal ion transport GO:0070838 172 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
epithelial cell development GO:0002064 159 0.014
organophosphate catabolic process GO:0046434 232 0.014
development of primary male sexual characteristics GO:0046546 88 0.014
regulation of hormone levels GO:0010817 211 0.014
regulation of cellular response to stress GO:0080135 159 0.014
protein acylation GO:0043543 64 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
cytoplasmic transport GO:0016482 234 0.014
male meiosis i GO:0007141 16 0.014
glycerolipid metabolic process GO:0046486 122 0.014
negative regulation of protein modification process GO:0031400 163 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
sequestering of calcium ion GO:0051208 18 0.014
sensory perception of light stimulus GO:0050953 54 0.014
intracellular mrna localization GO:0008298 4 0.014
cardiac muscle cell contraction GO:0086003 7 0.014
negative regulation of cell cycle phase transition GO:1901988 48 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.014
mitotic cytokinesis GO:0000281 4 0.014
regulation of dna endoreduplication GO:0032875 3 0.014
negative regulation of endothelial cell migration GO:0010596 4 0.013
multi multicellular organism process GO:0044706 109 0.013
gene silencing GO:0016458 38 0.013
meiotic sister chromatid segregation GO:0045144 6 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
muscle tissue development GO:0060537 308 0.013
regulation of proteolysis GO:0030162 164 0.013
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.013
calcium ion transmembrane transport GO:0070588 85 0.013
meiosis ii GO:0007135 7 0.013
regulation of organelle organization GO:0033043 289 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
regulation of eosinophil migration GO:2000416 2 0.013
eosinophil migration GO:0072677 3 0.013
muscle cell development GO:0055001 133 0.013
oocyte construction GO:0007308 2 0.013
purine containing compound metabolic process GO:0072521 311 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
regulation of tube size GO:0035150 57 0.013
negative regulation of cell cycle GO:0045786 123 0.013
urogenital system development GO:0001655 261 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
neuromuscular process GO:0050905 99 0.013
skeletal system development GO:0001501 356 0.013
oocyte development GO:0048599 33 0.013
single fertilization GO:0007338 82 0.013
synaptic transmission GO:0007268 329 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
myelination GO:0042552 74 0.013
male germ line stem cell asymmetric division GO:0048133 2 0.013
activation of immune response GO:0002253 138 0.013
terpenoid metabolic process GO:0006721 25 0.013
regulation of secretion GO:0051046 274 0.013
carbohydrate homeostasis GO:0033500 128 0.012
leukocyte migration GO:0050900 124 0.012
cellular response to lipid GO:0071396 145 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
retina morphogenesis in camera type eye GO:0060042 45 0.012
metal ion homeostasis GO:0055065 189 0.012
learning or memory GO:0007611 148 0.012
regulation of protein kinase b signaling GO:0051896 56 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
negative regulation of mitotic cell cycle GO:0045930 58 0.012
regulation of neuron projection development GO:0010975 169 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
hepaticobiliary system development GO:0061008 67 0.011
glycosylation GO:0070085 62 0.011
regulation of binding GO:0051098 111 0.011
cytokine production GO:0001816 319 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
membrane depolarization GO:0051899 64 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
rna processing GO:0006396 105 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
adaptive immune response GO:0002250 155 0.011
positive regulation of meiosis i GO:0060903 5 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
nucleoside metabolic process GO:0009116 246 0.011
macromolecule glycosylation GO:0043413 55 0.011
regulation of reproductive process GO:2000241 66 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
positive regulation of nervous system development GO:0051962 221 0.011
double strand break repair via homologous recombination GO:0000724 21 0.011
glycoprotein metabolic process GO:0009100 116 0.011
protein glycosylation GO:0006486 55 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
regulation of cell motility GO:2000145 236 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
thymocyte migration GO:0072679 2 0.011
cofactor metabolic process GO:0051186 80 0.011
detection of light stimulus GO:0009583 25 0.011
regulation of muscle contraction GO:0006937 49 0.011
positive regulation of t cell activation GO:0050870 101 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.011
ear development GO:0043583 200 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
organic cyclic compound catabolic process GO:1901361 295 0.011
regulation of transcription by chromatin organization GO:0034401 0 0.011
neural tube development GO:0021915 160 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
peptide metabolic process GO:0006518 46 0.010
triglyceride metabolic process GO:0006641 51 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
positive regulation of leukocyte differentiation GO:1902107 86 0.010
actin filament based movement GO:0030048 23 0.010
regulation of interleukin 1 alpha secretion GO:0050705 3 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
negative regulation of dna dependent dna replication GO:2000104 1 0.010
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.010
nucleotide catabolic process GO:0009166 217 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
negative regulation of gene silencing GO:0060969 2 0.010
axonogenesis GO:0007409 274 0.010
nucleoside monophosphate metabolic process GO:0009123 85 0.010
compound eye development GO:0048749 1 0.010

Smc1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.054
disease of anatomical entity DOID:7 0 0.054
sensory system disease DOID:0050155 0 0.054
eye and adnexa disease DOID:1492 0 0.041
eye disease DOID:5614 0 0.022
retinal disease DOID:5679 0 0.019
disease of cellular proliferation DOID:14566 0 0.017
disease of metabolism DOID:0014667 0 0.013
cancer DOID:162 0 0.011