Mus musculus

47 known processes

Smn1

survival motor neuron 1

(Aliases: Smn,Gemin1,AI849087)

Smn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.579
release of cytochrome c from mitochondria GO:0001836 23 0.495
amine metabolic process GO:0009308 45 0.484
negative regulation of release of cytochrome c from mitochondria GO:0090201 6 0.475
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.434
Zebrafish
cell adhesion GO:0007155 329 0.399
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.396
rna splicing GO:0008380 54 0.386
Zebrafish
regulation of cellular amine metabolic process GO:0033238 20 0.352
regulation of cellular ketone metabolic process GO:0010565 66 0.318
regulation of mitochondrion organization GO:0010821 27 0.293
cation homeostasis GO:0055080 212 0.282
oocyte axis specification GO:0007309 2 0.281
regulation of apoptotic signaling pathway GO:2001233 197 0.276
apoptotic signaling pathway GO:0097190 306 0.275
protein catabolic process GO:0030163 221 0.258
microtubule based process GO:0007017 236 0.256
negative regulation of apoptotic signaling pathway GO:2001234 104 0.254
peptidyl amino acid modification GO:0018193 336 0.253
rna processing GO:0006396 105 0.251
Zebrafish
positive regulation of growth GO:0045927 104 0.246
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.229
oxidation reduction process GO:0055114 342 0.214
jak stat cascade GO:0007259 42 0.213
muscle tissue development GO:0060537 308 0.212
regulation of organelle organization GO:0033043 289 0.204
regulation of cell cycle process GO:0010564 160 0.203
regulation of cell cycle GO:0051726 281 0.203
Worm
atp metabolic process GO:0046034 75 0.198
cellular amine metabolic process GO:0044106 44 0.196
histone modification GO:0016570 159 0.195
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.191
cellular ketone metabolic process GO:0042180 84 0.184
stem cell differentiation GO:0048863 268 0.183
nuclear membrane organization GO:0071763 4 0.179
protein alkylation GO:0008213 81 0.175
digestive system development GO:0055123 200 0.169
cellular response to gamma radiation GO:0071480 4 0.168
chromatin modification GO:0016568 187 0.163
camera type eye development GO:0043010 266 0.162
mrna processing GO:0006397 63 0.162
Zebrafish
macromolecule catabolic process GO:0009057 281 0.159
locomotory behavior GO:0007626 195 0.154
positive regulation of cellular amine metabolic process GO:0033240 5 0.154
regulation of cell adhesion GO:0030155 154 0.150
cajal body organization GO:0030576 1 0.149
cellular metal ion homeostasis GO:0006875 151 0.146
action potential GO:0001508 78 0.137
stem cell development GO:0048864 219 0.135
axonogenesis GO:0007409 274 0.135
methylation GO:0032259 134 0.132
germ cell development GO:0007281 185 0.131
Worm
regulation of cellular amino acid metabolic process GO:0006521 5 0.130
central nervous system neuron differentiation GO:0021953 162 0.129
negative regulation of cellular amine metabolic process GO:0033239 1 0.128
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.126
cellular response to radiation GO:0071478 28 0.126
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.125
negative regulation of cell cycle GO:0045786 123 0.124
Worm
cellular response to oxidative stress GO:0034599 76 0.123
maturation of 5 8s rrna GO:0000460 1 0.120
cellular ion homeostasis GO:0006873 165 0.118
milk ejection GO:0060156 1 0.118
adult behavior GO:0030534 135 0.117
gonad development GO:0008406 141 0.117
striated muscle tissue development GO:0014706 293 0.116
metal ion homeostasis GO:0055065 189 0.116
signal transduction by p53 class mediator GO:0072331 51 0.114
cytoplasmic transport GO:0016482 234 0.113
meiotic cell cycle GO:0051321 122 0.111
Worm
g1 s transition of mitotic cell cycle GO:0000082 57 0.110
anatomical structure homeostasis GO:0060249 145 0.109
macromolecule methylation GO:0043414 120 0.109
protein processing GO:0016485 163 0.107
signal transduction in absence of ligand GO:0038034 55 0.103
regulation of cell growth GO:0001558 91 0.101
apoptotic mitochondrial changes GO:0008637 48 0.101
regulation of mitotic cell cycle GO:0007346 126 0.101
Worm
metencephalon development GO:0022037 89 0.099
cell substrate adhesion GO:0031589 130 0.098
regulation of release of cytochrome c from mitochondria GO:0090199 11 0.098
mrna metabolic process GO:0016071 84 0.097
Zebrafish
regulation of binding GO:0051098 111 0.096
cell cycle g1 s phase transition GO:0044843 57 0.095
gliogenesis GO:0042063 141 0.094
digestive tract development GO:0048565 190 0.093
ribonucleoprotein complex subunit organization GO:0071826 28 0.092
regulation of transferase activity GO:0051338 263 0.091
regulation of fibroblast proliferation GO:0048145 34 0.090
covalent chromatin modification GO:0016569 163 0.090
dephosphorylation GO:0016311 129 0.089
transmission of nerve impulse GO:0019226 76 0.088
retina development in camera type eye GO:0060041 119 0.088
protein methylation GO:0006479 81 0.087
rna splicing via transesterification reactions GO:0000375 43 0.087
Zebrafish
extrinsic apoptotic signaling pathway GO:0097191 126 0.087
organ growth GO:0035265 117 0.087
adult locomotory behavior GO:0008344 91 0.086
generation of precursor metabolites and energy GO:0006091 103 0.086
cell cycle checkpoint GO:0000075 47 0.086
cellular response to sterol depletion GO:0071501 4 0.085
regulation of protein localization GO:0032880 231 0.085
peptidyl tyrosine modification GO:0018212 145 0.084
wound healing GO:0042060 157 0.084
stem cell maintenance GO:0019827 130 0.082
positive regulation of programmed cell death GO:0043068 218 0.082
body morphogenesis GO:0010171 45 0.080
skeletal muscle organ development GO:0060538 163 0.080
cellular response to dna damage stimulus GO:0006974 207 0.080
sequestering of calcium ion GO:0051208 18 0.080
negative regulation of mitotic cell cycle GO:0045930 58 0.079
Worm
cell fate commitment GO:0045165 210 0.079
chromatin organization GO:0006325 206 0.078
purine ribonucleotide metabolic process GO:0009150 290 0.078
t cell proliferation GO:0042098 120 0.077
positive regulation of protein kinase activity GO:0045860 144 0.075
negative regulation of cellular component organization GO:0051129 194 0.075
regulation of protein catabolic process GO:0042176 108 0.075
myeloid cell differentiation GO:0030099 233 0.075
positive regulation of cell development GO:0010720 237 0.074
cation transport GO:0006812 399 0.073
protein import into nucleus GO:0006606 95 0.073
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.072
spinal cord motor neuron differentiation GO:0021522 35 0.072
rna dependent dna replication GO:0006278 3 0.071
telomere maintenance via telomerase GO:0007004 1 0.071
establishment of glial blood brain barrier GO:0060857 2 0.070
negative regulation of organelle organization GO:0010639 90 0.070
fibroblast proliferation GO:0048144 35 0.070
leukocyte differentiation GO:0002521 342 0.069
development of primary sexual characteristics GO:0045137 143 0.068
negative regulation of cell proliferation GO:0008285 296 0.068
gene silencing GO:0016458 38 0.068
nuclear division GO:0000280 158 0.067
protein localization to organelle GO:0033365 185 0.067
negative regulation of dna replication GO:0008156 4 0.067
axon guidance GO:0007411 141 0.067
Zebrafish
nucleoside monophosphate metabolic process GO:0009123 85 0.067
negative regulation of protein metabolic process GO:0051248 282 0.066
cellular calcium ion homeostasis GO:0006874 119 0.066
regulation of cellular component biogenesis GO:0044087 181 0.066
regulation of jak stat cascade GO:0046425 34 0.065
mitochondrion organization GO:0007005 134 0.064
positive regulation of fibroblast proliferation GO:0048146 20 0.064
mitotic cell cycle GO:0000278 195 0.063
Worm
pole plasm assembly GO:0007315 2 0.063
oocyte construction GO:0007308 2 0.063
leukocyte proliferation GO:0070661 172 0.063
response to organic cyclic compound GO:0014070 198 0.063
regulation of cellular catabolic process GO:0031329 242 0.062
regulation of erk1 and erk2 cascade GO:0070372 71 0.062
histone methylation GO:0016571 71 0.062
telomere maintenance GO:0000723 19 0.061
positive regulation of cell growth GO:0030307 33 0.061
regulation of ion homeostasis GO:2000021 64 0.061
multicellular organism growth GO:0035264 161 0.060
nucleocytoplasmic transport GO:0006913 139 0.059
ras protein signal transduction GO:0007265 77 0.059
response to superoxide GO:0000303 16 0.059
ameboidal type cell migration GO:0001667 128 0.058
female gamete generation GO:0007292 74 0.058
regulation of cardiac muscle cell proliferation GO:0060043 23 0.058
positive regulation of kinase activity GO:0033674 155 0.057
regulation of cellular response to stress GO:0080135 159 0.057
negative regulation of growth GO:0045926 99 0.057
mitotic cell cycle process GO:1903047 159 0.057
lymphocyte differentiation GO:0030098 242 0.056
macromolecular complex disassembly GO:0032984 43 0.056
oocyte differentiation GO:0009994 35 0.056
divalent inorganic cation transport GO:0072511 178 0.055
t cell activation GO:0042110 289 0.055
organonitrogen compound catabolic process GO:1901565 264 0.055
nucleoside phosphate metabolic process GO:0006753 338 0.055
mesoderm development GO:0007498 100 0.055
regulation of leukocyte differentiation GO:1902105 159 0.055
rhythmic process GO:0048511 174 0.054
ossification GO:0001503 216 0.054
microtubule cytoskeleton organization GO:0000226 157 0.053
mapk cascade GO:0000165 281 0.053
regulation of proteasomal protein catabolic process GO:0061136 46 0.053
protein maturation GO:0051604 176 0.052
sensory organ morphogenesis GO:0090596 242 0.052
forebrain development GO:0030900 302 0.052
axon ensheathment GO:0008366 76 0.052
regulation of cell cycle g1 s phase transition GO:1902806 35 0.052
srebp signaling pathway GO:0032933 4 0.052
hindbrain development GO:0030902 128 0.051
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.051
compound eye development GO:0048749 1 0.051
skeletal system morphogenesis GO:0048705 203 0.051
regulation of mitotic cell cycle phase transition GO:1901990 73 0.050
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.050
negative regulation of phosphate metabolic process GO:0045936 184 0.049
cellular respiration GO:0045333 38 0.049
small gtpase mediated signal transduction GO:0007264 97 0.049
purine nucleotide metabolic process GO:0006163 302 0.049
iron sulfur cluster assembly GO:0016226 3 0.049
telomere capping GO:0016233 4 0.049
axon target recognition GO:0007412 4 0.049
membrane organization GO:0061024 245 0.048
regulation of anatomical structure size GO:0090066 178 0.048
mesenchyme development GO:0060485 152 0.048
neuronal action potential GO:0019228 54 0.048
sensory perception GO:0007600 245 0.048
purine nucleoside metabolic process GO:0042278 241 0.048
cardiac muscle cell proliferation GO:0060038 31 0.047
regulation of organ growth GO:0046620 61 0.047
negative regulation of mitochondrion organization GO:0010823 9 0.047
negative regulation of homeostatic process GO:0032845 71 0.047
striated muscle cell proliferation GO:0014855 39 0.046
chemotaxis GO:0006935 247 0.046
Zebrafish
meiotic nuclear division GO:0007126 115 0.046
ventral spinal cord development GO:0021517 48 0.045
oocyte anterior posterior axis specification GO:0007314 2 0.045
response to oxidative stress GO:0006979 123 0.045
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.045
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.045
regulation of cytoplasmic transport GO:1903649 112 0.044
regulation of muscle cell apoptotic process GO:0010660 17 0.044
cellular chemical homeostasis GO:0055082 215 0.044
dendrite development GO:0016358 115 0.044
Zebrafish
ion transmembrane transport GO:0034220 361 0.044
multicellular organismal signaling GO:0035637 91 0.044
calcium ion transport GO:0006816 159 0.044
cellular protein complex assembly GO:0043623 116 0.044
Worm
endothelial cell differentiation GO:0045446 41 0.044
cellular protein catabolic process GO:0044257 155 0.043
ncrna processing GO:0034470 26 0.043
maturation of lsu rrna GO:0000470 1 0.043
response to oxygen levels GO:0070482 62 0.043
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.043
calcium ion transport into cytosol GO:0060402 48 0.043
limb development GO:0060173 166 0.042
spermatogenesis GO:0007283 284 0.042
regulation of cardiac muscle tissue development GO:0055024 31 0.042
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.042
regulation of chromosome organization GO:0033044 83 0.042
reactive oxygen species metabolic process GO:0072593 84 0.042
positive regulation of keratinocyte proliferation GO:0010838 4 0.042
cellular homeostasis GO:0019725 240 0.042
cell cycle arrest GO:0007050 37 0.042
positive regulation of transferase activity GO:0051347 167 0.041
dna biosynthetic process GO:0071897 22 0.041
hematopoietic stem cell differentiation GO:0060218 8 0.041
embryonic placenta development GO:0001892 98 0.041
cellular macromolecule catabolic process GO:0044265 206 0.040
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.040
positive regulation of muscle tissue development GO:1901863 32 0.040
energy derivation by oxidation of organic compounds GO:0015980 77 0.040
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.040
heterocycle catabolic process GO:0046700 280 0.039
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 1 0.039
negative regulation of phosphorus metabolic process GO:0010563 184 0.039
regulation of lymphocyte proliferation GO:0050670 117 0.039
regulation of membrane potential GO:0042391 192 0.038
establishment of protein localization to organelle GO:0072594 118 0.038
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.038
transmembrane transport GO:0055085 412 0.038
positive regulation of hydrolase activity GO:0051345 148 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.038
regulation of neuron differentiation GO:0045664 281 0.038
cell aging GO:0007569 35 0.038
hematopoietic progenitor cell differentiation GO:0002244 143 0.037
regulation of heart growth GO:0060420 31 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.037
regulation of cell activation GO:0050865 289 0.037
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.036
regulation of renin secretion into blood stream GO:1900133 4 0.036
cellular amino acid metabolic process GO:0006520 103 0.036
angiogenesis GO:0001525 201 0.036
protein targeting GO:0006605 143 0.036
single organism nuclear import GO:1902593 95 0.036
negative regulation of cell cycle process GO:0010948 69 0.036
olfactory learning GO:0008355 2 0.036
cardiocyte differentiation GO:0035051 87 0.036
neural crest cell migration GO:0001755 32 0.036
positive regulation of apoptotic signaling pathway GO:2001235 95 0.035
regulation of feeding behavior GO:0060259 3 0.035
myelination GO:0042552 74 0.035
positive regulation of mitochondrion organization GO:0010822 17 0.035
signal transduction involved in cell cycle checkpoint GO:0072395 3 0.035
muscle cell differentiation GO:0042692 261 0.035
Worm
genitalia development GO:0048806 37 0.035
regulation of myeloid cell differentiation GO:0045637 96 0.034
response to hypoxia GO:0001666 58 0.034
chromosome segregation GO:0007059 48 0.034
skeletal system development GO:0001501 356 0.034
cellular divalent inorganic cation homeostasis GO:0072503 127 0.034
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 3 0.033
organelle fission GO:0048285 170 0.033
modification dependent macromolecule catabolic process GO:0043632 133 0.033
positive regulation of cell adhesion GO:0045785 80 0.032
protein import GO:0017038 101 0.032
response to oxygen radical GO:0000305 16 0.032
ribosome biogenesis GO:0042254 20 0.032
protein localization to nucleus GO:0034504 121 0.032
regulation of cell motility GO:2000145 236 0.032
purine nucleoside monophosphate catabolic process GO:0009128 58 0.031
av node cell to bundle of his cell communication GO:0086067 2 0.031
glycosyl compound metabolic process GO:1901657 246 0.031
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.031
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 3 0.031
regionalization GO:0003002 337 0.031
localization within membrane GO:0051668 4 0.031
response to alcohol GO:0097305 48 0.031
regulation of secretion GO:0051046 274 0.030
hexose transport GO:0008645 56 0.030
mitochondrial dna repair GO:0043504 3 0.030
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.030
ensheathment of neurons GO:0007272 76 0.030
cellular protein complex disassembly GO:0043624 36 0.030
proteasomal protein catabolic process GO:0010498 98 0.030
response to light stimulus GO:0009416 135 0.030
regulation of protein transport GO:0051223 163 0.030
regulation of protein kinase activity GO:0045859 232 0.030
protein modification by small protein conjugation GO:0032446 187 0.030
chromosome organization involved in meiosis GO:0070192 39 0.030
sequestering of metal ion GO:0051238 19 0.030
erk1 and erk2 cascade GO:0070371 77 0.030
peptidyl tyrosine phosphorylation GO:0018108 143 0.029
double strand break repair GO:0006302 48 0.029
establishment or maintenance of cell polarity GO:0007163 86 0.029
iron ion homeostasis GO:0055072 36 0.029
dna repair GO:0006281 107 0.029
response to uv GO:0009411 44 0.029
glycosyl compound catabolic process GO:1901658 206 0.029
nucleus organization GO:0006997 45 0.029
embryonic organ morphogenesis GO:0048562 276 0.029
purine containing compound metabolic process GO:0072521 311 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.029
regulation of action potential GO:0098900 4 0.029
regulation of mapk cascade GO:0043408 248 0.029
cardiac muscle tissue growth GO:0055017 37 0.029
mrna splicing via spliceosome GO:0000398 43 0.028
Zebrafish
cell differentiation in spinal cord GO:0021515 53 0.028
regulation of homeostatic process GO:0032844 182 0.028
glial cell differentiation GO:0010001 131 0.028
digestive tract morphogenesis GO:0048546 147 0.028
regulation of intracellular transport GO:0032386 159 0.028
positive regulation of protein oligomerization GO:0032461 4 0.028
negative regulation of protein catabolic process GO:0042177 36 0.028
regulation of ventricular cardiac muscle cell membrane depolarization GO:0060373 2 0.028
nuclear transport GO:0051169 139 0.028
t cell differentiation GO:0030217 174 0.027
neuroblast differentiation GO:0014016 2 0.027
t cell differentiation in thymus GO:0033077 77 0.027
regulation of cell substrate adhesion GO:0010810 73 0.027
response to inorganic substance GO:0010035 96 0.027
intestinal epithelial structure maintenance GO:0060729 4 0.027
epithelial tube morphogenesis GO:0060562 303 0.027
neural tube development GO:0021915 160 0.027
negative regulation of nervous system development GO:0051961 156 0.027
protein localization to membrane GO:0072657 108 0.027
wnt signaling pathway GO:0016055 188 0.027
male gamete generation GO:0048232 285 0.027
lactation GO:0007595 25 0.026
striated muscle myosin thick filament assembly GO:0071688 1 0.026
Worm
myosin filament assembly GO:0031034 2 0.026
Worm
regulation of nucleocytoplasmic transport GO:0046822 73 0.026
response to organonitrogen compound GO:0010243 246 0.026
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.026
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.026
protein localization to nuclear envelope GO:0090435 2 0.026
regulation of striated muscle cell differentiation GO:0051153 81 0.026
negative regulation of protein modification process GO:0031400 163 0.026
dna recombination GO:0006310 92 0.025
regulation of protein secretion GO:0050708 82 0.025
regulation of body fluid levels GO:0050878 162 0.025
molting cycle GO:0042303 90 0.025
Worm
modification dependent protein catabolic process GO:0019941 133 0.025
negative regulation of organ growth GO:0046621 17 0.025
regulation of protein targeting GO:1903533 61 0.025
positive regulation of nervous system development GO:0051962 221 0.025
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.025
neuron apoptotic process GO:0051402 142 0.025
regulation of wound healing GO:0061041 40 0.025
regulation of microtubule based process GO:0032886 52 0.025
response to radiation GO:0009314 165 0.025
positive regulation of vasoconstriction GO:0045907 4 0.025
cell division GO:0051301 120 0.025
heart morphogenesis GO:0003007 178 0.025
dna replication GO:0006260 52 0.025
cellular response to ionizing radiation GO:0071479 11 0.025
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.025
monosaccharide transport GO:0015749 58 0.024
mesoderm formation GO:0001707 62 0.024
metallo sulfur cluster assembly GO:0031163 3 0.024
cell substrate junction assembly GO:0007044 24 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.024
response to drug GO:0042493 75 0.024
kidney development GO:0001822 213 0.024
nucleotide excision repair GO:0006289 13 0.024
ribosomal small subunit biogenesis GO:0042274 4 0.024
negative regulation of cell cycle phase transition GO:1901988 48 0.024
regulation of tissue remodeling GO:0034103 38 0.024
ribosomal large subunit assembly GO:0000027 2 0.024
regulation of kinase activity GO:0043549 249 0.024
cell junction assembly GO:0034329 52 0.024
negative regulation of phosphorylation GO:0042326 166 0.024
lymphocyte proliferation GO:0046651 164 0.023
inflammatory response GO:0006954 244 0.023
foramen ovale closure GO:0035922 1 0.023
organelle assembly GO:0070925 177 0.023
Worm
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.023
cytosolic calcium ion homeostasis GO:0051480 70 0.023
negative regulation of keratinocyte differentiation GO:0045617 4 0.023
blood circulation GO:0008015 195 0.023
body fluid secretion GO:0007589 53 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
positive regulation of b cell apoptotic process GO:0002904 4 0.023
regulation of blood pressure GO:0008217 93 0.022
regulation of cellular component size GO:0032535 121 0.022
regulation of lymphocyte differentiation GO:0045619 107 0.022
oogenesis GO:0048477 56 0.022
multi multicellular organism process GO:0044706 109 0.022
regulation of mrna metabolic process GO:1903311 43 0.022
mitochondrial genome maintenance GO:0000002 15 0.022
formation of primary germ layer GO:0001704 77 0.022
cellular component assembly involved in morphogenesis GO:0010927 139 0.022
Worm
oligodendrocyte differentiation GO:0048709 53 0.022
positive regulation of striated muscle tissue development GO:0045844 31 0.022
negative regulation of neuron death GO:1901215 98 0.022
negative regulation of epithelial cell proliferation GO:0050680 64 0.022
myeloid cell homeostasis GO:0002262 114 0.022
regulation of nuclear division GO:0051783 56 0.022
cardiac chamber development GO:0003205 108 0.022
positive regulation of muscle cell differentiation GO:0051149 39 0.021
meiosis i GO:0007127 60 0.021
neuron migration GO:0001764 122 0.021
positive regulation of protein modification process GO:0031401 299 0.021
muscle contraction GO:0006936 101 0.021
regulation of ras protein signal transduction GO:0046578 114 0.021
negative regulation of leukocyte proliferation GO:0070664 46 0.021
mesonephric tubule development GO:0072164 94 0.021
negative regulation of t cell proliferation GO:0042130 38 0.021
rrna processing GO:0006364 10 0.021
feeding behavior GO:0007631 62 0.021
Worm
positive regulation of epithelial cell proliferation GO:0050679 68 0.021
regulation of myotube differentiation GO:0010830 62 0.020
cellular response to light stimulus GO:0071482 19 0.020
regeneration GO:0031099 38 0.020
astrocyte differentiation GO:0048708 43 0.020
muscle cell development GO:0055001 133 0.020
Worm
regulation of cell aging GO:0090342 9 0.020
atrial ventricular junction remodeling GO:0003294 2 0.020
male sex differentiation GO:0046661 109 0.020
glial cell development GO:0021782 54 0.020
cell communication by chemical coupling GO:0010643 2 0.020
megakaryocyte differentiation GO:0030219 26 0.020
release of sequestered calcium ion into cytosol GO:0051209 42 0.020
intracellular protein transport GO:0006886 204 0.020
transition metal ion homeostasis GO:0055076 54 0.020
cellular response to external stimulus GO:0071496 88 0.020
aromatic compound catabolic process GO:0019439 286 0.020
positive regulation of myeloid cell differentiation GO:0045639 43 0.020
carbohydrate transport GO:0008643 62 0.020
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
leukocyte mediated cytotoxicity GO:0001909 62 0.020
regulation of intracellular protein transport GO:0033157 82 0.019
establishment of protein localization to membrane GO:0090150 54 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.019
glucose transport GO:0015758 56 0.019
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.019
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.019

Smn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscle tissue disease DOID:66 0 0.209
musculoskeletal system disease DOID:17 0 0.209
muscular disease DOID:0080000 0 0.209
myopathy DOID:423 0 0.209
disease of anatomical entity DOID:7 0 0.209
cardiomyopathy DOID:0050700 0 0.173
cardiovascular system disease DOID:1287 0 0.173
heart disease DOID:114 0 0.173
intrinsic cardiomyopathy DOID:0060036 0 0.173
muscular dystrophy DOID:9884 0 0.130
cancer DOID:162 0 0.086
disease of cellular proliferation DOID:14566 0 0.086
organ system cancer DOID:0050686 0 0.077
nervous system disease DOID:863 0 0.071
central nervous system disease DOID:331 0 0.036
immune system cancer DOID:0060083 0 0.036
hematologic cancer DOID:2531 0 0.036
congenital muscular dystrophy DOID:0050557 0 0.033
gastrointestinal system cancer DOID:3119 0 0.032
dilated cardiomyopathy DOID:12930 0 0.026
intestinal cancer DOID:10155 0 0.025
colon cancer DOID:219 0 0.025
colorectal cancer DOID:9256 0 0.025
large intestine cancer DOID:5672 0 0.025
bone marrow cancer DOID:4960 0 0.022
neurodegenerative disease DOID:1289 0 0.020
spinocerebellar ataxia DOID:1441 0 0.020
spinocerebellar degeneration DOID:2478 0 0.020