Mus musculus

0 known processes

Smurf2

SMAD specific E3 ubiquitin protein ligase 2

(Aliases: 2810411E22Rik,AI558114,AI649275)

Smurf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.829
proteasomal protein catabolic process GO:0010498 98 0.748
Mouse
non canonical wnt signaling pathway GO:0035567 33 0.661
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.650
Mouse
establishment of planar polarity GO:0001736 28 0.646
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.629
ubiquitin dependent protein catabolic process GO:0006511 129 0.604
Human Mouse Fly
modification dependent protein catabolic process GO:0019941 133 0.554
Human Mouse Fly
cell junction maintenance GO:0034331 4 0.549
morphogenesis of a polarized epithelium GO:0001738 37 0.530
modification dependent macromolecule catabolic process GO:0043632 133 0.489
Human Mouse Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.471
establishment of tissue polarity GO:0007164 28 0.448
regulation of establishment of planar polarity GO:0090175 28 0.424
regulation of transferase activity GO:0051338 263 0.422
cellular amino acid metabolic process GO:0006520 103 0.418
macromolecule catabolic process GO:0009057 281 0.413
Human Mouse Fly
regulation of cellular amine metabolic process GO:0033238 20 0.410
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.378
Human Mouse Fly
regulation of kinase activity GO:0043549 249 0.373
positive regulation of cellular catabolic process GO:0031331 148 0.368
amine metabolic process GO:0009308 45 0.362
positive regulation of cellular amine metabolic process GO:0033240 5 0.353
negative regulation of protein modification process GO:0031400 163 0.340
lamellipodium organization GO:0097581 29 0.340
negative regulation of kinase activity GO:0033673 81 0.338
synapse organization GO:0050808 125 0.333
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.331
regulation of actin filament bundle assembly GO:0032231 18 0.321
regulation of lamellipodium assembly GO:0010591 3 0.319
regulation of cellular component biogenesis GO:0044087 181 0.295
Mouse
negative regulation of phosphorylation GO:0042326 166 0.288
Mouse
response to osmotic stress GO:0006970 21 0.286
Mouse
convergent extension GO:0060026 14 0.285
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.264
negative regulation of phosphorus metabolic process GO:0010563 184 0.259
Mouse
actin filament organization GO:0007015 113 0.258
regulation of cell projection organization GO:0031344 206 0.257
Mouse
cellular ketone metabolic process GO:0042180 84 0.256
regulation of cellular ketone metabolic process GO:0010565 66 0.256
negative regulation of phosphate metabolic process GO:0045936 184 0.254
Mouse
cellular amine metabolic process GO:0044106 44 0.254
cellular protein catabolic process GO:0044257 155 0.242
Human Mouse Fly
regulation of protein catabolic process GO:0042176 108 0.237
Mouse
epithelial tube morphogenesis GO:0060562 303 0.234
regulation of organ morphogenesis GO:2000027 144 0.231
ras protein signal transduction GO:0007265 77 0.231
cell junction organization GO:0034330 77 0.224
Mouse
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.223
canonical wnt signaling pathway GO:0060070 130 0.223
actin filament bundle assembly GO:0051017 40 0.218
dna metabolic process GO:0006259 303 0.218
cellular response to dna damage stimulus GO:0006974 207 0.213
cellular macromolecule catabolic process GO:0044265 206 0.204
Human Mouse Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.203
cerebral cortex radially oriented cell migration GO:0021799 31 0.201
regulation of protein kinase activity GO:0045859 232 0.200
lateral inhibition GO:0046331 1 0.196
negative regulation of transferase activity GO:0051348 85 0.195
membrane organization GO:0061024 245 0.185
negative regulation of protein metabolic process GO:0051248 282 0.175
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.172
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.172
regulation of peptidyl serine phosphorylation GO:0033135 39 0.172
regulation of neuron projection development GO:0010975 169 0.170
Mouse
regulation of protein localization GO:0032880 231 0.167
negative regulation of molecular function GO:0044092 258 0.164
Mouse
cell fate commitment GO:0045165 210 0.162
positive regulation of protein phosphorylation GO:0001934 242 0.161
gland development GO:0048732 330 0.159
positive regulation of cellular protein catabolic process GO:1903364 34 0.158
neural precursor cell proliferation GO:0061351 121 0.156
wnt signaling pathway GO:0016055 188 0.155
regulation of neuron differentiation GO:0045664 281 0.153
Mouse
positive regulation of cell projection organization GO:0031346 95 0.150
cell cell junction organization GO:0045216 72 0.150
Mouse
regulation of actin cytoskeleton organization GO:0032956 84 0.150
protein modification by small protein conjugation GO:0032446 187 0.146
Human Mouse Fly
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.146
developmental growth involved in morphogenesis GO:0060560 138 0.145
positive regulation of lamellipodium organization GO:1902745 3 0.144
positive regulation of proteolysis GO:0045862 85 0.144
purine ribonucleotide metabolic process GO:0009150 290 0.144
filopodium assembly GO:0046847 19 0.133
negative regulation of cellular protein metabolic process GO:0032269 247 0.133
determination of left right symmetry GO:0007368 80 0.127
regulation of mapk cascade GO:0043408 248 0.123
Mouse
regulation of cell cycle GO:0051726 281 0.122
morphogenesis of embryonic epithelium GO:0016331 159 0.122
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.122
germ cell development GO:0007281 185 0.121
Fly
positive regulation of protein catabolic process GO:0045732 60 0.118
Mouse
wound healing GO:0042060 157 0.117
regulation of gtp catabolic process GO:0033124 113 0.116
regulation of cytoskeleton organization GO:0051493 122 0.114
guanosine containing compound catabolic process GO:1901069 144 0.114
stress activated mapk cascade GO:0051403 80 0.110
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.109
development of primary sexual characteristics GO:0045137 143 0.108
circulatory system process GO:0003013 197 0.108
Mouse
actin cytoskeleton organization GO:0030036 220 0.108
endomembrane system organization GO:0010256 147 0.108
stress activated protein kinase signaling cascade GO:0031098 81 0.106
Mouse
regulation of binding GO:0051098 111 0.106
epidermis development GO:0008544 187 0.105
telencephalon development GO:0021537 186 0.105
pallium development GO:0021543 120 0.105
regulation of proteasomal protein catabolic process GO:0061136 46 0.105
regulation of cellular response to stress GO:0080135 159 0.104
Mouse
regulation of cell cycle process GO:0010564 160 0.103
protein localization to membrane GO:0072657 108 0.102
tube formation GO:0035148 140 0.101
plasma membrane organization GO:0007009 90 0.101
cerebral cortex development GO:0021987 86 0.100
cerebral cortex cell migration GO:0021795 44 0.100
negative chemotaxis GO:0050919 14 0.100
ear development GO:0043583 200 0.100
cell substrate adhesion GO:0031589 130 0.099
regulation of canonical wnt signaling pathway GO:0060828 82 0.098
regulation of stress activated mapk cascade GO:0032872 69 0.098
Mouse
ribose phosphate metabolic process GO:0019693 291 0.098
gonad development GO:0008406 141 0.097
negative regulation of cell fate specification GO:0009996 4 0.096
oocyte axis specification GO:0007309 2 0.095
heterocycle catabolic process GO:0046700 280 0.094
regulation of actin filament based process GO:0032970 99 0.093
purine nucleotide catabolic process GO:0006195 211 0.093
regulation of response to wounding GO:1903034 189 0.093
immune effector process GO:0002252 321 0.090
Mouse
positive regulation of transferase activity GO:0051347 167 0.090
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.090
asymmetric neuroblast division GO:0055059 1 0.089
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.089
Fly
epidermis morphogenesis GO:0048730 33 0.089
bone development GO:0060348 120 0.088
neuron projection guidance GO:0097485 141 0.088
regulation of cell adhesion GO:0030155 154 0.088
axonogenesis GO:0007409 274 0.086
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.086
regulation of protein binding GO:0043393 60 0.086
regulation of cellular protein catabolic process GO:1903362 61 0.086
endodermal cell fate specification GO:0001714 4 0.085
heart morphogenesis GO:0003007 178 0.084
Mouse
digestive system development GO:0055123 200 0.084
Fly
mitotic cell cycle process GO:1903047 159 0.084
cellular lipid metabolic process GO:0044255 323 0.084
positive regulation of protein modification process GO:0031401 299 0.083
positive regulation of lamellipodium assembly GO:0010592 2 0.082
cellular nitrogen compound catabolic process GO:0044270 280 0.082
sensory organ morphogenesis GO:0090596 242 0.081
blood circulation GO:0008015 195 0.080
Mouse
determination of digestive tract left right asymmetry GO:0071907 1 0.079
organic cyclic compound catabolic process GO:1901361 295 0.079
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.078
exocrine system development GO:0035272 45 0.078
positive regulation of cell development GO:0010720 237 0.078
organonitrogen compound catabolic process GO:1901565 264 0.078
positive regulation of wnt signaling pathway GO:0030177 45 0.077
embryonic organ morphogenesis GO:0048562 276 0.077
guanosine containing compound metabolic process GO:1901068 144 0.076
regulation of proteolysis GO:0030162 164 0.075
intracellular mrna localization GO:0008298 4 0.075
forebrain cell migration GO:0021885 58 0.075
organelle localization GO:0051640 179 0.075
purine nucleotide metabolic process GO:0006163 302 0.074
intracellular protein transport GO:0006886 204 0.074
cell adhesion GO:0007155 329 0.072
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.072
regulation of actin filament polymerization GO:0030833 38 0.072
microtubule based process GO:0007017 236 0.071
retina development in camera type eye GO:0060041 119 0.071
cellular response to growth factor stimulus GO:0071363 197 0.071
Mouse Fly
regulation of wnt signaling pathway GO:0030111 123 0.071
nucleotide metabolic process GO:0009117 332 0.071
neural tube development GO:0021915 160 0.070
protein localization to microtubule cytoskeleton GO:0072698 8 0.070
regulation of respiratory burst GO:0060263 2 0.069
purine nucleoside catabolic process GO:0006152 205 0.068
inner ear morphogenesis GO:0042472 101 0.068
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.068
Mouse
stem cell development GO:0048864 219 0.068
protein catabolic process GO:0030163 221 0.067
Human Mouse Fly
axon guidance GO:0007411 141 0.067
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.066
regulation of jnk cascade GO:0046328 62 0.066
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.066
skin development GO:0043588 220 0.065
microtubule cytoskeleton organization GO:0000226 157 0.065
regionalization GO:0003002 337 0.064
aromatic compound catabolic process GO:0019439 286 0.064
forebrain development GO:0030900 302 0.063
ectodermal digestive tract development GO:0007439 1 0.063
gtp metabolic process GO:0046039 144 0.063
regulation of lymphocyte activation GO:0051249 240 0.063
Mouse
immune response regulating cell surface receptor signaling pathway involved in phagocytosis GO:0002433 1 0.062
homeostasis of number of cells GO:0048872 210 0.062
striated muscle tissue development GO:0014706 293 0.062
positive regulation of neuron projection development GO:0010976 79 0.061
cell cell signaling involved in cell fate commitment GO:0045168 35 0.061
cell junction assembly GO:0034329 52 0.061
Mouse
telencephalon cell migration GO:0022029 55 0.060
skin morphogenesis GO:0043589 38 0.060
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.060
Fly
organophosphate catabolic process GO:0046434 232 0.060
purine containing compound metabolic process GO:0072521 311 0.060
regulation of nucleotide metabolic process GO:0006140 169 0.060
regulation of cardiac cell fate specification GO:2000043 1 0.060
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.060
Human Fly
positive regulation of mapk cascade GO:0043410 170 0.059
cell division GO:0051301 120 0.059
regulation of cell substrate adhesion GO:0010810 73 0.059
protein localization to nucleus GO:0034504 121 0.059
hair follicle cell proliferation GO:0071335 3 0.059
nucleobase containing small molecule metabolic process GO:0055086 352 0.059
regulation of ras gtpase activity GO:0032318 88 0.058
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.058
convergent extension involved in axis elongation GO:0060028 7 0.058
positive regulation of kinase activity GO:0033674 155 0.057
mitotic cell cycle GO:0000278 195 0.057
genitalia development GO:0048806 37 0.057
purine containing compound catabolic process GO:0072523 213 0.057
positive regulation of protein kinase activity GO:0045860 144 0.057
digestive tract development GO:0048565 190 0.057
Fly
olfactory bulb development GO:0021772 30 0.057
regulation of purine nucleotide metabolic process GO:1900542 169 0.056
carbohydrate derivative catabolic process GO:1901136 231 0.056
salivary gland development GO:0007431 37 0.055
defense response to other organism GO:0098542 197 0.055
Mouse
positive regulation of stress fiber assembly GO:0051496 9 0.055
asymmetric stem cell division GO:0098722 3 0.055
positive regulation of actin filament bundle assembly GO:0032233 11 0.054
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.054
nucleoside phosphate metabolic process GO:0006753 338 0.054
negative regulation of wnt signaling pathway GO:0030178 73 0.054
regulation of protein serine threonine kinase activity GO:0071900 157 0.054
chemotaxis GO:0006935 247 0.053
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.052
somatic stem cell maintenance GO:0035019 47 0.052
ear morphogenesis GO:0042471 118 0.052
positive regulation of lipid kinase activity GO:0090218 11 0.052
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.052
camera type eye development GO:0043010 266 0.052
maintenance of location GO:0051235 89 0.051
regulation of jun kinase activity GO:0043506 40 0.051
regulation of cytokine production GO:0001817 266 0.051
ribonucleoside triphosphate catabolic process GO:0009203 199 0.051
positive regulation of gtp catabolic process GO:0033126 85 0.051
dorsal ventral axon guidance GO:0033563 3 0.050
salivary gland morphogenesis GO:0007435 33 0.050
protein localization to organelle GO:0033365 185 0.050
pole plasm assembly GO:0007315 2 0.050
cardiac cell fate specification GO:0060912 2 0.049
apical junction assembly GO:0043297 15 0.049
Mouse
heart induction GO:0003129 2 0.049
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.049
defense response to bacterium GO:0042742 119 0.049
oocyte construction GO:0007308 2 0.049
peptidyl serine phosphorylation GO:0018105 74 0.048
negative regulation of cellular component organization GO:0051129 194 0.048
dna repair GO:0006281 107 0.048
cytoplasmic transport GO:0016482 234 0.048
dendrite development GO:0016358 115 0.047
Mouse
ribonucleotide metabolic process GO:0009259 291 0.047
regulation of nucleotide catabolic process GO:0030811 122 0.047
nucleotide catabolic process GO:0009166 217 0.047
regulation of cell projection assembly GO:0060491 38 0.047
regulation of stress fiber assembly GO:0051492 15 0.047
ribonucleoside catabolic process GO:0042454 206 0.047
adherens junction maintenance GO:0034334 1 0.047
tube closure GO:0060606 91 0.046
single organism nuclear import GO:1902593 95 0.046
positive regulation of filopodium assembly GO:0051491 10 0.045
rho protein signal transduction GO:0007266 32 0.045
ribonucleoside metabolic process GO:0009119 245 0.045
protein modification by small protein conjugation or removal GO:0070647 207 0.045
Human Mouse Fly
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.045
positive regulation of cell adhesion GO:0045785 80 0.045
single organism cell adhesion GO:0098602 156 0.044
regulation of protein complex assembly GO:0043254 83 0.044
regulation of stem cell differentiation GO:2000736 50 0.044
cell growth GO:0016049 130 0.044
nucleoside metabolic process GO:0009116 246 0.043
nucleoside triphosphate metabolic process GO:0009141 230 0.043
establishment of organelle localization GO:0051656 122 0.043
positive regulation of nervous system development GO:0051962 221 0.043
purine nucleoside metabolic process GO:0042278 241 0.043
nucleoside catabolic process GO:0009164 206 0.042
purine ribonucleotide catabolic process GO:0009154 208 0.042
positive regulation of substrate adhesion dependent cell spreading GO:1900026 8 0.042
engulfment of apoptotic cell GO:0043652 3 0.042
regulation of cardioblast differentiation GO:0051890 3 0.042
substrate adhesion dependent cell spreading GO:0034446 30 0.042
female sex differentiation GO:0046660 84 0.042
positive regulation of non canonical wnt signaling pathway GO:2000052 6 0.041
embryonic epithelial tube formation GO:0001838 130 0.041
regulation of establishment of protein localization GO:0070201 181 0.041
ribonucleoside triphosphate metabolic process GO:0009199 220 0.041
endoderm development GO:0007492 45 0.041
neuron projection extension GO:1990138 64 0.041
glycosyl compound metabolic process GO:1901657 246 0.041
negative regulation of neuron differentiation GO:0045665 101 0.041
neural plate elongation GO:0014022 4 0.041
neuromuscular process GO:0050905 99 0.041
neuron migration GO:0001764 122 0.040
cell proliferation in forebrain GO:0021846 30 0.040
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.040
Fly
negative regulation of synapse assembly GO:0051964 3 0.040
skeletal system development GO:0001501 356 0.040
ribonucleotide catabolic process GO:0009261 208 0.039
regulation of purine nucleotide catabolic process GO:0033121 122 0.039
regulation of endocytosis GO:0030100 69 0.039
primary neural tube formation GO:0014020 95 0.039
leukocyte chemotaxis GO:0030595 69 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.039
respiratory system development GO:0060541 190 0.038
positive regulation of gtpase activity GO:0043547 85 0.038
ossification GO:0001503 216 0.038
Mouse
neural tube formation GO:0001841 108 0.038
cytoplasmic microtubule organization GO:0031122 14 0.038
leukocyte migration GO:0050900 124 0.037
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.037
Mouse
positive regulation of jun kinase activity GO:0043507 30 0.037
neutrophil chemotaxis GO:0030593 36 0.037
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.037
Fly
multicellular organism growth GO:0035264 161 0.037
t cell anergy GO:0002870 4 0.036
Mouse
ameboidal type cell migration GO:0001667 128 0.036
endocytosis GO:0006897 168 0.036
muscle tissue development GO:0060537 308 0.036
jnk cascade GO:0007254 72 0.036
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.036
Mouse
negative regulation of nervous system development GO:0051961 156 0.035
hindbrain development GO:0030902 128 0.035
nephrogenic mesenchyme development GO:0072076 3 0.035
purine nucleoside triphosphate metabolic process GO:0009144 226 0.035
mapk cascade GO:0000165 281 0.035
Mouse
negative regulation of growth GO:0045926 99 0.035
regulation of cellular catabolic process GO:0031329 242 0.035
peptidyl amino acid modification GO:0018193 336 0.035
heart contraction GO:0060047 93 0.035
developmental cell growth GO:0048588 84 0.035
regulation of cell activation GO:0050865 289 0.034
Mouse
actin cytoskeleton reorganization GO:0031532 21 0.034
endodermal cell fate commitment GO:0001711 12 0.034
positive regulation of stress activated mapk cascade GO:0032874 48 0.034
developmental induction GO:0031128 34 0.034
purine ribonucleoside catabolic process GO:0046130 205 0.034
heart field specification GO:0003128 6 0.034
epithelial cell development GO:0002064 159 0.034
cardiac endothelial cell differentiation GO:0003348 4 0.034
adherens junction assembly GO:0034333 22 0.034
regulation of microtubule cytoskeleton organization GO:0070507 37 0.034
t cell proliferation GO:0042098 120 0.033
Mouse
regulation of actin polymerization or depolymerization GO:0008064 45 0.033
establishment or maintenance of cell polarity GO:0007163 86 0.033
posttranscriptional regulation of gene expression GO:0010608 155 0.033
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.033
regulation of protein heterodimerization activity GO:0043497 2 0.033
erythrocyte differentiation GO:0030218 88 0.033
epithelial cell morphogenesis GO:0003382 41 0.033
hyperosmotic response GO:0006972 4 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.033
gtp catabolic process GO:0006184 143 0.033
organelle fission GO:0048285 170 0.032
regulation of rho protein signal transduction GO:0035023 71 0.032
segmentation GO:0035282 93 0.032
regulation of membrane potential GO:0042391 192 0.032
maternal determination of anterior posterior axis embryo GO:0008358 2 0.032
regulation of bmp signaling pathway GO:0030510 60 0.032
Fly
positive regulation of neuron differentiation GO:0045666 141 0.032
cell recognition GO:0008037 83 0.032
negative regulation of lymphocyte activation GO:0051250 91 0.032
Mouse
muscle fiber development GO:0048747 76 0.032
cellular component assembly involved in morphogenesis GO:0010927 139 0.032
cell type specific apoptotic process GO:0097285 268 0.032
skeletal system morphogenesis GO:0048705 203 0.031
lymphocyte homeostasis GO:0002260 64 0.031
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.031
positive regulation of organelle organization GO:0010638 128 0.031
myotube differentiation GO:0014902 105 0.031
protein ubiquitination GO:0016567 171 0.031
Human Mouse Fly
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.031
nuclear division GO:0000280 158 0.031
oocyte anterior posterior axis specification GO:0007314 2 0.030
regulation of hydrolase activity GO:0051336 246 0.030
actin polymerization or depolymerization GO:0008154 54 0.030
action potential GO:0001508 78 0.030
regulation of intracellular transport GO:0032386 159 0.030
peptidyl tyrosine modification GO:0018212 145 0.030
cardiocyte differentiation GO:0035051 87 0.030
regulation of protein transport GO:0051223 163 0.030
negative regulation of cell activation GO:0050866 111 0.030
Mouse
regulation of anatomical structure size GO:0090066 178 0.030
protein polymerization GO:0051258 57 0.029
regulation of non canonical wnt signaling pathway GO:2000050 12 0.029
lipid localization GO:0010876 126 0.029
regulation of ion transport GO:0043269 215 0.029
Mouse
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.029
Human
regulation of t cell activation GO:0050863 170 0.029
Mouse
protein targeting GO:0006605 143 0.029
regulation of cytoplasmic transport GO:1903649 112 0.029
motor neuron axon guidance GO:0008045 26 0.029
neurotransmitter secretion GO:0007269 62 0.028
semaphorin plexin signaling pathway GO:0071526 21 0.028
regulation of heart induction GO:0090381 2 0.028
protein localization to microtubule GO:0035372 3 0.028
positive regulation of cellular component biogenesis GO:0044089 94 0.028
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.027
establishment of monopolar cell polarity GO:0061162 8 0.027
midbrain development GO:0030901 35 0.027
regulation of defense response GO:0031347 233 0.027
Mouse
cardiac muscle tissue development GO:0048738 130 0.027
actin mediated cell contraction GO:0070252 15 0.027
cardiac septum development GO:0003279 59 0.027
myeloid cell homeostasis GO:0002262 114 0.027
postsynaptic membrane organization GO:0001941 18 0.027
positive regulation of jnk cascade GO:0046330 46 0.027
glycosyl compound catabolic process GO:1901658 206 0.027
cardiac chamber development GO:0003205 108 0.026
striated muscle cell development GO:0055002 125 0.026
protein maturation GO:0051604 176 0.026
myeloid cell differentiation GO:0030099 233 0.026
epithelial tube formation GO:0072175 130 0.026
negative regulation of ossification GO:0030279 49 0.026
Mouse
neuron death GO:0070997 154 0.026
regulation of substrate adhesion dependent cell spreading GO:1900024 12 0.026
regulation of smad protein import into nucleus GO:0060390 3 0.026
keratinocyte development GO:0003334 10 0.026
stem cell proliferation GO:0072089 117 0.026
positive regulation of ras gtpase activity GO:0032320 65 0.026
multi multicellular organism process GO:0044706 109 0.026
convergent extension involved in neural plate elongation GO:0022007 4 0.026
tissue remodeling GO:0048771 102 0.026
regulation of muscle system process GO:0090257 80 0.025
response to growth factor GO:0070848 198 0.025
Mouse Fly
regulation of cellular response to growth factor stimulus GO:0090287 82 0.025
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.025
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.025
neutrophil migration GO:1990266 37 0.025
muscle system process GO:0003012 141 0.025
embryonic limb morphogenesis GO:0030326 126 0.025
organic hydroxy compound metabolic process GO:1901615 203 0.025
female gonad development GO:0008585 71 0.025
regulation of actin filament length GO:0030832 45 0.025
regulation of lymphocyte proliferation GO:0050670 117 0.025
Mouse
positive regulation of nucleoside metabolic process GO:0045979 91 0.025
regulation of vacuole organization GO:0044088 4 0.025
regulation of vesicle mediated transport GO:0060627 139 0.025
regulation of organelle organization GO:0033043 289 0.024
cardiac chamber morphogenesis GO:0003206 93 0.024
leukocyte differentiation GO:0002521 342 0.024
negative regulation of cell cycle GO:0045786 123 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.024
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.024
b cell activation GO:0042113 161 0.024
positive regulation of map kinase activity GO:0043406 84 0.024
regulation of t cell anergy GO:0002667 4 0.024
Mouse
regulation of protein tyrosine kinase activity GO:0061097 17 0.024
cochlea development GO:0090102 35 0.024
leukocyte homeostasis GO:0001776 79 0.024
regulation of nucleocytoplasmic transport GO:0046822 73 0.024
single organismal cell cell adhesion GO:0016337 131 0.024
neuron recognition GO:0008038 25 0.024
regulation of tight junction assembly GO:2000810 2 0.023
Mouse
stem cell maintenance GO:0019827 130 0.023
lymphocyte anergy GO:0002249 4 0.023
Mouse
positive regulation of t cell anergy GO:0002669 4 0.023
Mouse
bmp signaling pathway GO:0030509 93 0.023
Fly
positive regulation of intracellular transport GO:0032388 70 0.023
cytokine production GO:0001816 319 0.023
sensory perception of mechanical stimulus GO:0050954 107 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
regulation of neuron death GO:1901214 134 0.023
positive regulation of response to wounding GO:1903036 66 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
blastocyst development GO:0001824 80 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
Mouse
adherens junction organization GO:0034332 28 0.022
regulation of hair follicle cell proliferation GO:0071336 2 0.022
positive regulation of cell proliferation involved in heart valve morphogenesis GO:0003251 1 0.022
regulation of synapse assembly GO:0051963 29 0.022
sensory perception GO:0007600 245 0.022
multi organism behavior GO:0051705 62 0.022
regulation of map kinase activity GO:0043405 120 0.022
syncytium formation GO:0006949 43 0.022
negative regulation of cytokine production GO:0001818 84 0.022
inflammatory response GO:0006954 244 0.022
cellular homeostasis GO:0019725 240 0.022
organ induction GO:0001759 21 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
regulation of ras protein signal transduction GO:0046578 114 0.021
regulation of protein maturation GO:1903317 96 0.021
peripheral nervous system development GO:0007422 53 0.021

Smurf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.074
disease of cellular proliferation DOID:14566 0 0.074