|
|
regionalization
|
GO:0003002 |
337 |
0.988
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.982
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.981
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.981
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.970
|
Fly |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.970
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
68 |
0.962
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.961
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.958
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.950
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.947
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
18 |
0.945
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.943
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.943
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.939
|
Zebrafish Fly |
|
|
cartilage development
|
GO:0051216 |
140 |
0.931
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.927
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.927
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.926
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.926
|
Mouse Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.925
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.922
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.918
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.910
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.908
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.907
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.906
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.901
|
Fly |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.900
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.897
|
Fly |
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.897
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
68 |
0.889
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.885
|
Mouse |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.881
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.879
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.876
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.868
|
Zebrafish Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.867
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.865
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
22 |
0.862
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.859
|
Mouse Fly |
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
23 |
0.854
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
44 |
0.854
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.852
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.852
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.850
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.848
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.840
|
Mouse Fly |
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.839
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.837
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.836
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.835
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
49 |
0.828
|
Fly |
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.827
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.827
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.826
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.826
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.825
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.825
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.823
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.822
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.817
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.812
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.811
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.807
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.807
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.802
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.801
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.790
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.789
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.788
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.785
|
Mouse Fly |
|
|
pallium development
|
GO:0021543 |
120 |
0.784
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.780
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.778
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.778
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.775
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.769
|
Mouse |
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.768
|
Fly |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.768
|
|
|
|
heart valve morphogenesis
|
GO:0003179 |
21 |
0.768
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.767
|
|
|
|
diencephalon development
|
GO:0021536 |
63 |
0.767
|
|
|
|
astrocyte fate commitment
|
GO:0060018 |
4 |
0.757
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.753
|
|
|
|
regulation of chondrocyte differentiation
|
GO:0032330 |
33 |
0.744
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.743
|
|
|
|
trophoblast giant cell differentiation
|
GO:0060707 |
15 |
0.742
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.742
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.740
|
|
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.733
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.733
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.732
|
|
|
|
cell migration involved in heart development
|
GO:0060973 |
8 |
0.732
|
Mouse |
|
|
connective tissue development
|
GO:0061448 |
179 |
0.731
|
|
|
|
cardiac septum development
|
GO:0003279 |
59 |
0.725
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.723
|
|
|
|
somite development
|
GO:0061053 |
81 |
0.717
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.716
|
Fly |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.714
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
13 |
0.711
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.709
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.702
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.701
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.699
|
|
|
|
cell proliferation involved in outflow tract morphogenesis
|
GO:0061325 |
4 |
0.698
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.695
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
13 |
0.694
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.691
|
Fly |
|
|
tube formation
|
GO:0035148 |
140 |
0.688
|
|
|
|
endocardial cushion morphogenesis
|
GO:0003203 |
18 |
0.679
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.679
|
|
|
|
positive regulation of secondary heart field cardioblast proliferation
|
GO:0072513 |
4 |
0.667
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
54 |
0.666
|
|
|
|
endocardial cushion to mesenchymal transition involved in heart valve formation
|
GO:0003199 |
4 |
0.664
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.661
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.655
|
Fly |
|
|
ureteric bud morphogenesis
|
GO:0060675 |
62 |
0.653
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.651
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.647
|
|
|
|
ventricular septum development
|
GO:0003281 |
42 |
0.647
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
46 |
0.647
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
63 |
0.646
|
|
|
|
endoderm formation
|
GO:0001706 |
20 |
0.645
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.644
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.642
|
|
|
|
head morphogenesis
|
GO:0060323 |
34 |
0.641
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.636
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.634
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.632
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.626
|
Mouse |
|
|
lung development
|
GO:0030324 |
164 |
0.625
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.624
|
Zebrafish Mouse |
|
|
negative regulation of fat cell differentiation
|
GO:0045599 |
36 |
0.621
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.601
|
|
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.594
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.594
|
|
|
|
cell fate determination
|
GO:0001709 |
32 |
0.592
|
Fly |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.591
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.590
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.587
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.586
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.586
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.580
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.579
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.579
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.574
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.570
|
Mouse |
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.570
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
83 |
0.568
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.567
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.565
|
|
|
|
neural crest cell development
|
GO:0014032 |
48 |
0.565
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.561
|
Mouse Fly |
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.558
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.557
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.554
|
|
|
|
cartilage morphogenesis
|
GO:0060536 |
11 |
0.546
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.546
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
59 |
0.546
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
33 |
0.543
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.543
|
|
|
|
heart valve development
|
GO:0003170 |
23 |
0.539
|
|
|
|
aortic valve morphogenesis
|
GO:0003180 |
4 |
0.538
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.532
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.528
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.528
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.526
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.525
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.525
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
45 |
0.519
|
Zebrafish Mouse |
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.517
|
|
|
|
mitral valve development
|
GO:0003174 |
4 |
0.517
|
|
|
|
cell proliferation involved in heart morphogenesis
|
GO:0061323 |
15 |
0.516
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.514
|
|
|
|
positive regulation of ureteric bud formation
|
GO:0072107 |
3 |
0.511
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.498
|
Fly |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.495
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.489
|
Human Mouse |
|
|
regulation of stem cell differentiation
|
GO:2000736 |
50 |
0.488
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.488
|
Human Mouse |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.488
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.487
|
|
|
|
positive regulation of kidney development
|
GO:0090184 |
28 |
0.486
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.483
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
83 |
0.480
|
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
53 |
0.476
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.466
|
Human Mouse |
|
|
endoderm development
|
GO:0007492 |
45 |
0.463
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.459
|
|
|
|
autonomic nervous system development
|
GO:0048483 |
43 |
0.455
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.454
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
22 |
0.448
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.445
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
26 |
0.438
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.437
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
15 |
0.437
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.437
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.433
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.430
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.427
|
Fly |
|
|
appendage development
|
GO:0048736 |
166 |
0.425
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.421
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
65 |
0.418
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.417
|
|
|
|
mesenchyme morphogenesis
|
GO:0072132 |
32 |
0.417
|
|
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.414
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.409
|
Mouse |
|
|
mesonephros development
|
GO:0001823 |
97 |
0.407
|
|
|
|
endocardial cushion development
|
GO:0003197 |
26 |
0.405
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.404
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.404
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.403
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
72 |
0.402
|
Fly |
|
|
limb development
|
GO:0060173 |
166 |
0.400
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.399
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.398
|
|
|
|
positive regulation of branching involved in ureteric bud morphogenesis
|
GO:0090190 |
18 |
0.395
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.394
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.391
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.389
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.389
|
|
|
|
regulation of stem cell maintenance
|
GO:2000036 |
17 |
0.387
|
|
|
|
branching involved in ureteric bud morphogenesis
|
GO:0001658 |
56 |
0.387
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.384
|
Zebrafish Fly |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.383
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
63 |
0.382
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.382
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.382
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.381
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.380
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.379
|
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.379
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
51 |
0.378
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.376
|
|
|
|
pyramidal neuron migration
|
GO:0021852 |
1 |
0.372
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
47 |
0.371
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.369
|
|
|
|
lung morphogenesis
|
GO:0060425 |
50 |
0.368
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.368
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.367
|
|
|
|
midbrain development
|
GO:0030901 |
35 |
0.366
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.362
|
|
|
|
collagen fibril organization
|
GO:0030199 |
32 |
0.362
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
12 |
0.361
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.360
|
|
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
2 |
0.359
|
|
|
|
central nervous system vasculogenesis
|
GO:0022009 |
3 |
0.358
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.355
|
Human |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.355
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
52 |
0.355
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.353
|
|
|
|
transdifferentiation
|
GO:0060290 |
1 |
0.352
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
31 |
0.349
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.348
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.347
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.346
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.345
|
|
|
|
nephron tubule formation
|
GO:0072079 |
20 |
0.345
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.344
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.343
|
Mouse |
|
|
myoblast differentiation
|
GO:0045445 |
52 |
0.341
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.340
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.338
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.336
|
Mouse |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.333
|
|
|
|
embryonic digit morphogenesis
|
GO:0042733 |
56 |
0.333
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.329
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.327
|
|
|
|
mesoderm formation
|
GO:0001707 |
62 |
0.326
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.325
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
27 |
0.324
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.322
|
Mouse |
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.322
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.322
|
|
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
22 |
0.321
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
44 |
0.320
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.320
|
Human |
|
|
metanephros development
|
GO:0001656 |
79 |
0.319
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.319
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.319
|
Fly |
|
|
mesenchymal cell proliferation
|
GO:0010463 |
44 |
0.316
|
|
|
|
definitive hemopoiesis
|
GO:0060216 |
20 |
0.314
|
|
|
|
spinal cord development
|
GO:0021510 |
81 |
0.313
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.313
|
|
|
|
neural crest cell migration
|
GO:0001755 |
32 |
0.313
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.311
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.307
|
|
|
|
glomerular mesangial cell development
|
GO:0072144 |
3 |
0.307
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.306
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.303
|
|
|
|
heart valve formation
|
GO:0003188 |
10 |
0.302
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.301
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
14 |
0.300
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.298
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
25 |
0.298
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.294
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.292
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.292
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.291
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
50 |
0.289
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.285
|
|
|
|
tendon cell differentiation
|
GO:0035990 |
4 |
0.285
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.279
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.278
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.277
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.277
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.276
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.274
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.274
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.274
|
Human |
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.273
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.272
|
|
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.269
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.269
|
|
|
|
regulation of organ formation
|
GO:0003156 |
34 |
0.268
|
|
|
|
thymus development
|
GO:0048538 |
41 |
0.267
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.265
|
|
|
|
cardiac right atrium morphogenesis
|
GO:0003213 |
3 |
0.264
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.263
|
Mouse |
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.262
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
18 |
0.262
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.262
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.261
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.261
|
|
|
|
cell differentiation involved in embryonic placenta development
|
GO:0060706 |
26 |
0.260
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.260
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.260
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.257
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.257
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.256
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
53 |
0.255
|
|
|
|
epithelial to mesenchymal transition involved in endocardial cushion formation
|
GO:0003198 |
10 |
0.254
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.252
|
|
|
|
hindbrain formation
|
GO:0021576 |
1 |
0.252
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.251
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.251
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.251
|
Mouse |
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.250
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.249
|
|
|
|
keratinocyte proliferation
|
GO:0043616 |
21 |
0.249
|
|
|
|
skin morphogenesis
|
GO:0043589 |
38 |
0.249
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
23 |
0.249
|
|
|
|
mesangial cell differentiation
|
GO:0072007 |
4 |
0.248
|
|
|
|
regulation of auditory receptor cell differentiation
|
GO:0045607 |
4 |
0.245
|
|
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.244
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.244
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.243
|
Mouse |
|
|
ventral spinal cord development
|
GO:0021517 |
48 |
0.242
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
4 |
0.240
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.240
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.238
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.238
|
Fly |
|
|
respiratory system development
|
GO:0060541 |
190 |
0.234
|
Fly |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.233
|
|
|
|
nerve development
|
GO:0021675 |
67 |
0.233
|
|
|
|
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
|
GO:2000802 |
1 |
0.231
|
|
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.231
|
|
|
|
artery development
|
GO:0060840 |
53 |
0.229
|
|
|
|
palate development
|
GO:0060021 |
76 |
0.229
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.229
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.229
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
35 |
0.228
|
|
|
|
renal vesicle induction
|
GO:0072034 |
3 |
0.228
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
53 |
0.228
|
|
|
|
paraxial mesoderm development
|
GO:0048339 |
18 |
0.228
|
|
|
|
endocardial cushion formation
|
GO:0003272 |
13 |
0.228
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.224
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.224
|
Human |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.223
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
31 |
0.222
|
|
|
|
positive regulation of inner ear receptor cell differentiation
|
GO:2000982 |
1 |
0.222
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.221
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.220
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.218
|
|
|
|
mammary gland duct morphogenesis
|
GO:0060603 |
38 |
0.218
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.217
|
|
|
|
cartilage condensation
|
GO:0001502 |
18 |
0.215
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.214
|
Mouse |
|
|
positive regulation of keratinocyte proliferation
|
GO:0010838 |
4 |
0.214
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.212
|
|
|
|
glial cell fate commitment
|
GO:0021781 |
14 |
0.211
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.211
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.207
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
13 |
0.206
|
Zebrafish |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.205
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.205
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.203
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.202
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.202
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.202
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.201
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.201
|
Mouse Fly |
|
|
synapse assembly
|
GO:0007416 |
56 |
0.200
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.200
|
|
|
|
midbrain hindbrain boundary maturation
|
GO:0021732 |
1 |
0.199
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.199
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.198
|
Mouse |
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.198
|
Fly |
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.197
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
33 |
0.196
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.195
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.195
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.194
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.194
|
|
|
|
positive regulation of mesonephros development
|
GO:0061213 |
20 |
0.191
|
|
|
|
regulation of cardioblast proliferation
|
GO:0003264 |
9 |
0.191
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.188
|
|
|
|
endocrine pancreas development
|
GO:0031018 |
29 |
0.186
|
|
|
|
positive regulation of cardiac muscle tissue development
|
GO:0055025 |
19 |
0.185
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
35 |
0.184
|
|
|
|
face development
|
GO:0060324 |
38 |
0.184
|
|
|
|
regulation of mesenchymal cell proliferation involved in ureter development
|
GO:0072199 |
3 |
0.184
|
|
|
|
regulation of kidney development
|
GO:0090183 |
40 |
0.183
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.183
|
|
|
|
embryonic heart tube formation
|
GO:0003144 |
1 |
0.181
|
|
|
|
cranial nerve development
|
GO:0021545 |
41 |
0.180
|
|
|
|
cellular response to bmp stimulus
|
GO:0071773 |
14 |
0.180
|
|
|
|
tendon formation
|
GO:0035992 |
4 |
0.180
|
|
|
|
regulation of ureteric bud formation
|
GO:0072106 |
3 |
0.179
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.178
|
|
|
|
positive regulation of cartilage development
|
GO:0061036 |
18 |
0.178
|
|
|
|
positive regulation of striated muscle tissue development
|
GO:0045844 |
31 |
0.178
|
|
|
|
positive regulation of neuroblast proliferation
|
GO:0002052 |
19 |
0.178
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.177
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.177
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
17 |
0.175
|
|
|
|
planar cell polarity pathway involved in outflow tract morphogenesis
|
GO:0061347 |
2 |
0.175
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.174
|
|
|
|
negative regulation of cartilage development
|
GO:0061037 |
17 |
0.174
|
|
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
37 |
0.173
|
|
|
|
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
|
GO:2000800 |
1 |
0.171
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.171
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.171
|
|
|
|
oviduct development
|
GO:0060066 |
3 |
0.171
|
|
|
|
regulation of vascular endothelial growth factor production
|
GO:0010574 |
13 |
0.169
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.168
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.168
|
Mouse |
|
|
developmental induction
|
GO:0031128 |
34 |
0.168
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.168
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.166
|
|
|
|
positive regulation of epithelial cell proliferation involved in lung morphogenesis
|
GO:0060501 |
3 |
0.166
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.166
|
|
|
|
somite rostral caudal axis specification
|
GO:0032525 |
13 |
0.165
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.165
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.165
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.164
|
|
|
|
aortic valve development
|
GO:0003176 |
5 |
0.164
|
|
|
|
regulation of morphogenesis of a branching structure
|
GO:0060688 |
53 |
0.163
|
Mouse |
|
|
hair follicle development
|
GO:0001942 |
85 |
0.163
|
|
|
|
positive regulation of mechanoreceptor differentiation
|
GO:0045633 |
1 |
0.163
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.163
|
|
|
|
cardiac atrium morphogenesis
|
GO:0003209 |
23 |
0.162
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.161
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.161
|
|
|
|
trachea cartilage morphogenesis
|
GO:0060535 |
4 |
0.161
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.160
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
26 |
0.159
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.159
|
|
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
21 |
0.159
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
47 |
0.158
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.158
|
|
|
|
auditory receptor cell fate determination
|
GO:0042668 |
3 |
0.158
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.158
|
Fly |
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.158
|
|
|
|
positive regulation of muscle tissue development
|
GO:1901863 |
32 |
0.157
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.156
|
|
|
|
endocardial cushion to mesenchymal transition
|
GO:0090500 |
5 |
0.156
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
40 |
0.156
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
26 |
0.156
|
|
|
|
auditory receptor cell fate specification
|
GO:0042667 |
1 |
0.156
|
|
|
|
positive regulation of cardiac muscle tissue growth
|
GO:0055023 |
15 |
0.155
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.155
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.155
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.155
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process
|
GO:2000763 |
1 |
0.154
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.154
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.154
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.153
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
23 |
0.153
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.153
|
|
|
|
positive regulation of auditory receptor cell differentiation
|
GO:0045609 |
1 |
0.153
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
27 |
0.151
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.151
|
|
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
15 |
0.151
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.150
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.149
|
Fly |
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.148
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.148
|
|
|
|
positive regulation of synaptic plasticity
|
GO:0031915 |
4 |
0.148
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.148
|
|
|
|
neuron fate specification
|
GO:0048665 |
30 |
0.147
|
|
|
|
negative regulation of myoblast differentiation
|
GO:0045662 |
18 |
0.147
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation
|
GO:0003257 |
3 |
0.146
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.146
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.145
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.145
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.144
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.143
|
|
|
|
nephric duct formation
|
GO:0072179 |
4 |
0.143
|
|
