|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.998
|
Mouse |
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.998
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.996
|
Mouse |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.996
|
Mouse |
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.993
|
Mouse |
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.989
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.988
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.988
|
Mouse |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.984
|
Mouse |
|
|
t cell activation
|
GO:0042110 |
289 |
0.982
|
Mouse |
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.979
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.979
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.977
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.974
|
Mouse |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.971
|
Mouse |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.968
|
Mouse |
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.966
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.966
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.963
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.961
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.960
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.959
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.954
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.950
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.948
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.947
|
Mouse |
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.939
|
Mouse |
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.938
|
Mouse |
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.937
|
Mouse |
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.928
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.927
|
Mouse |
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.921
|
Mouse |
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.919
|
Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.917
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.916
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.914
|
Mouse |
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.913
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.913
|
Mouse |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.909
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.909
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.905
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.898
|
Mouse |
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.897
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.893
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.875
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.870
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.869
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.865
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.864
|
Mouse |
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.860
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.857
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.857
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.855
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.853
|
Mouse |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.846
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.845
|
Mouse |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.844
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.842
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.842
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.838
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.836
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.834
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.832
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.832
|
|
|
|
negative regulation of t helper 1 cell differentiation
|
GO:0045626 |
3 |
0.830
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.824
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.818
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.817
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.817
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.815
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.814
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.810
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.805
|
Mouse |
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.802
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.801
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.794
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.791
|
|
|
|
spinal cord development
|
GO:0021510 |
81 |
0.790
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.789
|
Mouse |
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
14 |
0.789
|
Mouse |
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.784
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.783
|
Mouse |
|
|
skin development
|
GO:0043588 |
220 |
0.783
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.780
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.778
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.775
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.774
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.773
|
|
|
|
positive regulation of epithelial cell proliferation involved in lung morphogenesis
|
GO:0060501 |
3 |
0.768
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.765
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.765
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.765
|
Zebrafish |
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.763
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.762
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.762
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.759
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.757
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.750
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.747
|
Mouse |
|
|
stem cell development
|
GO:0048864 |
219 |
0.738
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.736
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.735
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.732
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.732
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.723
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.719
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.716
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.716
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.714
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.713
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.712
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.709
|
Mouse |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.706
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.704
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.704
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.702
|
Mouse |
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.698
|
Mouse |
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.694
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.693
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.693
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.692
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.689
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.688
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.687
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.681
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.678
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.678
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.678
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.674
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.673
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.669
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.668
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.667
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.663
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.660
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.653
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.651
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.647
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.642
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.637
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
18 |
0.631
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.630
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.626
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.621
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.620
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.619
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.617
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.617
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.613
|
Zebrafish Mouse |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.609
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.609
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.608
|
|
|
|
mammary gland duct morphogenesis
|
GO:0060603 |
38 |
0.604
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.604
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.598
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.597
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.597
|
Mouse |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.595
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.592
|
Mouse |
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.586
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.583
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.581
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.580
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.577
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.576
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.576
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.570
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.568
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.568
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.566
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.564
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.563
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.563
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.561
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.560
|
Mouse |
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.559
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.559
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.556
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.555
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.553
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.552
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.552
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.551
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.544
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.541
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.540
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.540
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.539
|
Mouse |
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.539
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.538
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.537
|
Mouse |
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.535
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.534
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.528
|
|
|
|
positive regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000563 |
1 |
0.526
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.526
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.525
|
Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.522
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.520
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.516
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.516
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.515
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.513
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.513
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.513
|
Mouse |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.511
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.511
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.509
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.507
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.505
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.504
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.503
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.503
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.502
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.499
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.498
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.497
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.496
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:0097296 |
2 |
0.495
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.493
|
Rat |
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.493
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.490
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.490
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.490
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.489
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.489
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.489
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.489
|
Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.488
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.487
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.487
|
|
|
|
t helper 1 cell cytokine production
|
GO:0035744 |
1 |
0.487
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.485
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.484
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.482
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.480
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.480
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.478
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.474
|
Mouse |
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.464
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.460
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.459
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.459
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.458
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.453
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.452
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.449
|
Mouse |
|
|
regulation of t cell apoptotic process
|
GO:0070232 |
28 |
0.449
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.449
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.448
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.448
|
Zebrafish |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.445
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.445
|
|
|
|
thymocyte apoptotic process
|
GO:0070242 |
19 |
0.444
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.444
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.442
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.442
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.441
|
|
|
|
regulation of t helper 1 cell cytokine production
|
GO:2000554 |
1 |
0.438
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.438
|
|
|
|
negative regulation of carbohydrate metabolic process
|
GO:0045912 |
19 |
0.434
|
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
24 |
0.433
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.429
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.428
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
111 |
0.426
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.426
|
Mouse |
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.424
|
|
|
|
positive regulation of growth hormone receptor signaling pathway
|
GO:0060399 |
3 |
0.423
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.422
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.422
|
|
|
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
14 |
0.418
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.416
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.413
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.411
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.410
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.409
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.408
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.408
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.408
|
Mouse |
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.405
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.405
|
Mouse |
|
|
hair cycle
|
GO:0042633 |
90 |
0.405
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.404
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.403
|
|
|
|
regulation of asymmetric cell division
|
GO:0009786 |
4 |
0.402
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.401
|
|
|
|
positive regulation of interleukin 1 beta production
|
GO:0032731 |
16 |
0.400
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.399
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.390
|
Rat |
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.389
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.386
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
24 |
0.386
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.384
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.382
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.381
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.381
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.381
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.381
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
3 |
0.381
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.380
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.380
|
|
|
|
astrocyte cell migration
|
GO:0043615 |
3 |
0.380
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.380
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.379
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.379
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.377
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.375
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.374
|
Mouse |
|
|
protein processing
|
GO:0016485 |
163 |
0.374
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.368
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.366
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.365
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.363
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.362
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
15 |
0.361
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.361
|
|
|
|
positive regulation of syncytium formation by plasma membrane fusion
|
GO:0060143 |
17 |
0.361
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.360
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.360
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.359
|
Mouse |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.358
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.357
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.356
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.349
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.349
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.347
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.347
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.346
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.345
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.345
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.345
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.344
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.343
|
Mouse |
|
|
interleukin 1 secretion
|
GO:0050701 |
16 |
0.343
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.343
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.342
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.342
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.341
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.340
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.339
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.339
|
Zebrafish |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.339
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.339
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.337
|
|
|
|
positive regulation of interleukin 1 production
|
GO:0032732 |
17 |
0.337
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.337
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.334
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.334
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.332
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.332
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.332
|
Mouse |
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.331
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.331
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.331
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.331
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.330
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
39 |
0.329
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.328
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.328
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.324
|
|
|
|
negative regulation of glycogen metabolic process
|
GO:0070874 |
2 |
0.321
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.319
|
Mouse |
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.318
|
|
|
|
myoblast differentiation
|
GO:0045445 |
52 |
0.317
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.317
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.316
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.316
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.314
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.312
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.310
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.309
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.308
|
|
|
|
regulation of polysaccharide metabolic process
|
GO:0032881 |
13 |
0.308
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.307
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.306
|
|
|
|
myoblast differentiation involved in skeletal muscle regeneration
|
GO:0014835 |
3 |
0.305
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.304
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.304
|
|
|
|
positive regulation of dna templated transcription initiation
|
GO:2000144 |
5 |
0.303
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.303
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.303
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.303
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.302
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.302
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.301
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.301
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.301
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.300
|
Mouse |
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.299
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.297
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.296
|
|
|
|
regulation of dendritic cell cytokine production
|
GO:0002730 |
2 |
0.296
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.295
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.295
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.294
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.293
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.292
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.292
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.291
|
Mouse |
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.290
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.290
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.290
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.290
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.290
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.289
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.289
|
Zebrafish |
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.287
|
|
|
|
negative regulation of cellular carbohydrate metabolic process
|
GO:0010677 |
19 |
0.287
|
|
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.285
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.284
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.284
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.283
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.282
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.280
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.279
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.279
|
Mouse |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.278
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
59 |
0.278
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.277
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.277
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.275
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.275
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.274
|
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
5 |
0.273
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.272
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.272
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.271
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.270
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.270
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.267
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.266
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.266
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.265
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.265
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.264
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.259
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.259
|
Zebrafish |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.259
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.257
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.254
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.253
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.252
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.251
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.250
|
|
|
|
response to interleukin 12
|
GO:0070671 |
2 |
0.250
|
|
|
|
regulation of cardiac muscle cell apoptotic process
|
GO:0010665 |
9 |
0.248
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.248
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.248
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.248
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.247
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.246
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.246
|
|
|
|
regulation of interleukin 1 secretion
|
GO:0050704 |
15 |
0.245
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.245
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.244
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.242
|
|
|
|
negative regulation of alpha beta t cell differentiation
|
GO:0046639 |
12 |
0.242
|
Mouse |
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.240
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.240
|
Zebrafish Mouse |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.239
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.238
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.238
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.237
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.236
|
|
|
|
regulation of heart growth
|
GO:0060420 |
31 |
0.235
|
|
|
|
regulation of dna binding
|
GO:0051101 |
39 |
0.234
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.234
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.234
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.232
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.228
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.226
|
|
|
|
hindbrain formation
|
GO:0021576 |
1 |
0.226
|
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
8 |
0.225
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.225
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.223
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.221
|
|
|
|
cellular response to interleukin 4
|
GO:0071353 |
21 |
0.221
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.221
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.221
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.220
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.219
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.219
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.219
|
Mouse |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.218
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.218
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.217
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.215
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.215
|
Mouse |
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.213
|
Mouse |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.213
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.212
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.211
|
|
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.211
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.210
|
Mouse |
|
|
renal tubule development
|
GO:0061326 |
87 |
0.210
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.209
|
|
